PROCEEDINGS OF TIIE ROYAL SOCIETY OF LONDON S e r ie s B CONTAINING PAPERS OF A BIOLOGICAL CHARACTER VOL. XCIX. LONDON: P rinted for THE ROYAL SOCIETY and S old by HARRISON AND SONS, LTD., ST. MARTIN’S LANE, PRINTERS IN ORDINARY TO HIS MAJESTY May, 1926. LONDON: HARRISON AND SONS, LTD., PRINTERS IN ORDINARY TO FTIS MAJESTY ST. MARTIN'S TANE. CONTENTS --------------- SERIES B. VOL. XCIX. PAOE No. B 694.—December 1, 1925. On the Supposed Pluri-segmental Innervation of Muscle Fibres. By L. N. Katz. Communicated by Prof. A. V. Hill, F.R S.............................................. ................ 1 Lactic Acid in Mammalian Cardiac Muscle.—Part I. The Stimulation Maximum. By L. N. Katz and C. N. H. Long. Communicated by Prof. A. V. Hill, F.R.S................................................................................................................ 8 Lactic Acid in Mammalian Cardiac Muscle.—Part II. The Rigor Mortis Maximum and the Normal Glycogen Content. By H. J. G. Hines, L. N. Katz, and C. N. H. Long. Communicated by Prof. A. V. Hill, F.R.S................................ 20 Lactic Acid in Mammalian Cardiac Muscle.—Part III. Changes in Hydrogen-ion Concentration. (Preliminary Note.) By L. N. Katz, Phyllis Tookey Kerridge, and C. N. H. Long. Communicated by Prof. A. V. Hill, F.R.S. ... 26 The Effect of Light on the Circulation. By D. T. Harris. Communicated by Prof. E. H. Starling, F.R.S......................................................................................... 28 The Mechanism of Muscular Contraction. By W. E. Garner, Reader in Physical Chemistry at University College, London. Communicated by Prof. A. V. Hill, F.R.S............................................................................................................................. 40 The Effects of Calcium and Potassium Ions on Urine Secretion, as Studied in the whole Animal. By L. Brull and F. Eichholtz. Communicated by Prof. E. H. Starling, Foulerton Professor of the Royal Society...................... 57 The Secretion of Inorganic Phosphate by the Kidney.—II. Influence of the Pituitary Gland and of the Wall of the Third Ventricle. By L. Brull and F. Eichholtz. Communicated by E. H. Starling, F.R.S., Foulerton Professor of the Royal Society ...................................................................................................... 70 Hydrolysis of Phosphoric Esters by the Kidney Vivo. By F. Eichholtz (Rock- feller Travelling Fellow), Robert Robison and L. Brull. Communicated by E. H. Starling, F.R.S., Foulerton Professor of the Royal Society ...................... 91 No. B 695.—January 1, 1926. Address of the President, Sir Charles Sherrington, O.M., at the Anniversary Meeting, November 30, 1925 ................................................................................... 107 A Critical Statistical Study of Experimental Data on the Effect of Minute Electric Currents on the Growth Rate of the Coleoptile of Barley. By F. G. Gregory and L. Batten. Communicated by Prof. V. H. Blackman, F.R.S....................... 122 IV PAG® Measurements of the Reversing Spiral in Cotton Hairs. By W. Lawrence Balls, F.R.S., and H. A. Hancock...................................................................................... 130 A Spirometer Method of Studying Continuously the Gaseous Metabolism of Man during and after Exercise. By K. Furusawa. Communicated by Prof. A. V. Hill, F.R.S........................................................................................................ 148 Muscular Exercise, Lactic Acid, and the Supply and Utilisation of Oxygen.— Part X III. The Gaseous Exchanges of Restricted Muscular Exercise in Man. By K. Furusawa. Communicated by Prof. A. Y. Hill, F.R.S............................. 155 Muscular Exercise, Lactic Acid, and the Supply and Utilisation of Oxygen.— Part XIV. The Relation in Man between the Oxygen Intake during Exercise and the Lactic Acid Content of the Muscles. By C. N. H. Long. Com­ municated by Prof. A. V. Hill, F.R.S..................................................................... 167 The Hydrogen-Ion Concentration and Oxidation-Reduction Potential of the Cell- Interior before and after Fertilisation and Cleavage : A Micro-Injection Study on Marine Eggs. By Joseph Needham, M.A., Ph.D., Fellow of Caius College, Cambridge, and Dorothy Moyle Needham, Girton College, Cambridge, Beit Memorial Research Fellow. Communicated by Sir Frederick Hopkins, F.R.S. ................................................................... 173 No. B 696.—February 1, 1926. Chlorocruorin : A Pigment allied to Haemoglobin. By H. Munro Fox, Fellow of Gonville and Caius College, Cambridge, and Balfour Student in the University. Communicated by Prof. J. Stanley Gardiner, F.R.S. (Plate 1)......................... 199 Effects of Ultra-Violet Radiation upon Involuntary Muscle, and the Supposed Physiological Interference of Visible Rays. By Y. Azuma and Leonard Hill, F.R.S............................................................................................................................ 221 The Early Development of Cavia : Note on Associated Remains of Previous Placentation. By Norman H. W. Maclaren. Communicated by Prof. T. H. Bryce, F.R.S. (Plate 2) .......................................................................................... 230 Studies on the Relation of Gonadic Structure to Plumage Characterisation in the Domestic Fowl.—I. Henny-Feathering in an Ovariotomised Hen with Active Testis Grafts. By A. W. Greenwood and F. A. E. Crew, Animal Breeding Research Department, University of Edinburgh. Communicated by Prof. R. C. Punnett, F.R.S. (Plates 3 and 4) 232 The Induction of Melanism in the Lepidoptera and its Subsequent Inheritance. By J. W. Heslop Harrison, D.Sc., and F. C. Garrett, D.Sc. Communicated by Prof. E. W. MacBride, F.R.S................................................................................... 241 No. B 697.—March 1, 1926. The Diffraction Method of Measuring the Diameters of Erythrocytes. By W. G. Millar, M.B., Ch.B., F.R.M.S. Communicated by Sir E. Sharpey Schafer, F.R.S............................................................................ 264 V PAGE The Metabolism of the Diabetic Individual during and after Muscular Exercise. By K. S. Hetzel and C. N. H. Long. Communicated by Prof. A. V. Hill, F.R.S............................................................................................................................ 279 A Closed-Circuit Heart-Lung Preparation.—Effect of Alterations in the Peri­ pheral Resistance and in the Capacity of the Circulation. By I. de Burgh Daly. Communicated by Prof. E. H. Starling, F.R.S.......................................... 306 The Heat Liberated by the Beating Heart. By E. Fischer (Rockefeller Fellow). Communicated by Prof. A. V. Hill, F.R.S............................................................... 326 No. B 698.—April 6, 1926. Experimental Studies on the Differentiation of Embryonic Tissues growing in vivo and in vitro.—I. The Development of the LTndifferentiated Limb-Bud (a) when Subcutaneously Grafted into the Post-Embryonic Chick and (b) when Cultivated in vitro. By T. S. P. Strangeways, Lecturer in Special Pathology, University of Cambridge, and Honor B. Fell, Ph.D., Beit Memorial Research Fellow. Communicated by Sir William Hardy, F.R.S. (Plates 5-13) .......... 340 The Meiotic Phase in Certain Mammals. By C. E. Walker, D.Sc., Department of Cytology, LTniversity of Liverpool. Communicated by J. B. Farmer, F.R.S. (Plates 14-16) .......................................................................................................... 366 The Effect of Insulin on the Dextrose Consumption of Perfused Skeletal Muscle. By Charles H. Best. Communicated by Dr. H. H. Dale, Sec. R.S...................... 375 Further Micro-Injection Studies on the Oxidation-Reduction Potential of the Cell- Interior. By Joseph Needham, M.A., Ph.D., Fellow of Cains College, Cambridge, and Dorothy Moyle Needham, Girton College, Cambridge, Beit Memorial Research Fellow. Communicated by Prof. Sir Frederick Hopkins, F.R.S............................................................................................................................ 383 The Mechanism of Ciliary Movement.—V. The Effect of Ions on the Duration of Beat. By J. Gray, King’s College, Cambridge. Communicated by Prof. Stanley Gardiner, F.R.S............................................................................................. 398 No. B 699.—May 1, 1926. Ibe Influence of Muscle Work on Metabolism in Varying Conditions of Diet. By E. P. Cathcart, F.R.S., and W. A. Burnett (late Lawrence Student), Institute of Physiology, Glasgow Universitv ........................................................ 405 The Life-Cycle of the Nodule Organism, Bacillus Radicicola (B e i j .), in Soil and it s Relation to the Infection of the Host Plant. By H. G. Thornton, B A., and N. Gangulee, Ph.D. Communicated by Sir John Russell, F.R.S....................... 427 Ultra-Violet Radiation and Metabolism, with a New Method for Estimating Metabolism. By J. Argyll Campbell. Communicated by Dr. Leonard Hill, F.R.S. (Plate 17) ................................................................................................. 451 A Study of Certain Forms of Inhibition and Acceleration of Haemolysis. By Eric Ponder. Communicated by Sir E. Sharpey Schafer, F.R.S........................ 461 vi PAG-E The Isolation of Some Hitherto Undescribed Products of Hydrolysis of Proteins. —Part II. By S. B. Schryver, Professor