PRESCRIBING PSYCHOTROPICS: MISUSE, ABUSE, DEPENDENCE, WITHDRAWAL AND ADDICTION EDITED BY : Fabrizio Schifano, Giovanni Martinotti and Stefania Chiappini PUBLISHED IN : Frontiers in Psychiatry Frontiers eBook Copyright Statement About Frontiers The copyright in the text of individual articles in this eBook is the Frontiers is more than just an open-access publisher of scholarly articles: it is a property of their respective authors or their respective institutions or pioneering approach to the world of academia, radically improving the way scholarly funders. The copyright in graphics research is managed. The grand vision of Frontiers is a world where all people have and images within each article may be subject to copyright of other an equal opportunity to seek, share and generate knowledge. Frontiers provides parties. 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Find out more on how ISSN 1664-8714 to host your own Frontiers Research Topic or contribute to one as an author by ISBN 978-2-88966-940-0 DOI 10.3389/978-2-88966-940-0 contacting the Frontiers Editorial Office: frontiersin.org/about/contact Frontiers in Psychiatry 1 June 2021 | Prescribing Psychotropics: Misuse Issues PRESCRIBING PSYCHOTROPICS: MISUSE, ABUSE, DEPENDENCE, WITHDRAWAL AND ADDICTION Topic Editors: Fabrizio Schifano, University of Hertfordshire, United Kingdom Giovanni Martinotti, University of Studies G. d’Annunzio Chieti and Pescara, Italy Stefania Chiappini, University of Hertfordshire, United Kingdom Citation: Schifano, F., Martinotti, G., Chiappini, S., eds. (2021). Prescribing Psychotropics: Misuse, Abuse, Dependence, Withdrawal and Addiction. Lausanne: Frontiers Media SA. doi: 10.3389/978-2-88966-940-0 Frontiers in Psychiatry 2 June 2021 | Prescribing Psychotropics: Misuse Issues Table of Contents 05 Editorial: Prescribing Psychotropics: Misuse, Abuse, Dependence, Withdrawal and Addiction Stefania Chiappini, Fabrizio Schifano and Giovanni Martinotti 08 Ranking the Harm of Psychoactive Drugs Including Prescription Analgesics to Users and Others–A Perspective of German Addiction Medicine Experts Udo Bonnet, Michael Specka, Michael Soyka, Thomas Alberti, Stefan Bender, Torsten Grigoleit, Leopold Hermle, Jörg Hilger, Thomas Hillemacher, Thomas Kuhlmann, Jens Kuhn, Christian Luckhaus, Christel Lüdecke, Jens Reimer, Udo Schneider, Welf Schroeder, Markus Stuppe, Gerhard A. Wiesbeck, Norbert Wodarz, Heath McAnally and Norbert Scherbaum 17 High-Dose Dependence and Cognitive Side Effects to Medical Prescription of Etizolam Stefano Tamburin, Elisa Mantovani, Anna Bertoldi, Angela Federico, Rebecca Casari and Fabio Lugoboni 22 Prescription Drug Misuse in “Clubbers” and Disco Goers in Ibiza Massimo di Giannantonio, Attilio Negri, Stefania Schiavone, Chiara Vannini, Mauro Pettorruso, Fabio De-Giorgio, Valeria Verrastro, Luigia Trabace, Mariangela Corbo, Rossella Gottardo, Cristian Camuto, Monica Mazzarino, Andrea Barra, Domenico De Berardis, Juan Iglesias Lopez, Cristina Merino Del Villar, Fabrizio Schifano and Giovanni Martinotti 31 Psychiatry Trainees’ Attitudes, Knowledge, and Training in Addiction Psychiatry—A European Survey Laura Orsolini, Irena Rojnić Palavra, Gabriele Duccio Papanti, Matej Potočan, Diego Quattrone, Matis Martens, Sandra Sklenářová, Jonna Levola, Leslie Grichy, Sean Naughton, Indre Kotryna Grinevičiene, Jelly Petra Kuiters, Tomasz M. Gondek, Anca-Livia Panfil, Milica M. Borovcanin, Alberto San Roman Uria, Ewelina Biskup, Ekin Sönmez Güngör, Marisa Casanova Dias, Sonila Tomori, Visnja Banjac, Petra Marinova-Djambazova and Mariana Pinto da Costa 43 Gabapentinoid Abuse in France: Evidence on Health Consequences and New Points of Vigilance Marine Tambon, Camille Ponté, Emilie Jouanjus, Nathalie Fouilhé, Joelle Micallef, Maryse Lapeyre-Mestre and the French Addictovigilance Network (FAN) 58 Continuous Infusion of Flumazenil in the Management of Benzodiazepines Detoxification Anna Benini, Rossella Gottardo, Cristiano Chiamulera, Anna Bertoldi, Lorenzo Zamboni and Fabio Lugoboni 65 Case Report: Treatment of Kratom Use Disorder With a Classical Tricyclic Antidepressant Alessandro E. Vento, Simone de Persis, Sergio De Filippis, Fabrizio Schifano, Flavia Napoletano, John M. Corkery and Georgios D. Kotzalidis Frontiers in Psychiatry 3 June 2021 | Prescribing Psychotropics: Misuse Issues 74 The Severity of Dependence Scale (SDS) for Codeine: Preliminary Investigation of the Psychometric Properties of the SDS in an Online Sample of Codeine Users From the UK Paolo Deluca, Michelle Foley, Jacklyn Dunne and Andreas Kimergård 82 Personality to Prescription Drug Misuse in Adolescents: Testing Affect Regulation, Psychological Dysregulation, and Deviance Proneness Pathways Sherry H. Stewart, Annie Chinneck, Kara Thompson, Mohammad H. Afzali, Raquel Nogueira-Arjona, Ioan T. Mahu and Patricia J. Conrod 97 Non-medical Use of Prescription Gabapentinoids (Gabapentin and Pregabalin) in Five European Countries Francina Fonseca, William Lenahan, Richard C. Dart, Esther Papaseit, Paul I. Dargan, David M. Wood, Marilena Guareschi, Icro Maremmani, Marc Auriacombe, Magí Farré, Norbert Scherbaum and Marta Torrens 107 Focus on Over-the-Counter Drugs’ Misuse: A Systematic Review on Antihistamines, Cough Medicines, and Decongestants Fabrizio Schifano, Stefania Chiappini, Andrea Miuli, Alessio Mosca, Maria Chiara Santovito, John M. Corkery, Amira Guirguis, Mauro Pettorruso, Massimo Di Giannantonio and Giovanni Martinotti 120 Early Detection of Prescription Drug Abuse Using Doctor Shopping Monitoring From Claims Databases: Illustration From the Experience of the French Addictovigilance Network Thomas Soeiro, Clémence Lacroix, Vincent Pradel, Maryse Lapeyre-Mestre and Joëlle Micallef 132 Assessment of the Safety Signal for the Abuse Potential of Pregabalin and Gabapentin Using the FAERS Database and Big Data Search Analytics Georgios Papazisis, Dimitrios Spachos, Spyridon Siafis, Niki Pandria, Eleni Deligianni, Ioannis Tsakiridis and Antonios Goulas Frontiers in Psychiatry 4 June 2021 | Prescribing Psychotropics: Misuse Issues EDITORIAL published: 30 April 2021 doi: 10.3389/fpsyt.2021.688434 Editorial: Prescribing Psychotropics: Misuse, Abuse, Dependence, Withdrawal and Addiction Stefania Chiappini 1,2*†, Fabrizio Schifano 1† and Giovanni Martinotti 1,2† 1 Psychopharmacology,