39th Congress of the EAPCCT Naples, 21 – 24 May 2019 Provisional Scientific Programme Current to date: 18 March 2019 1 Provisional Scientific Programme Current to date: 18 March 2019 39th Congress of the EAPCCT Naples, 21 – 24 May 2019 Pre-Congress Symposium Continuing Education in Clinical Toxicology 21 May 2019 2 Provisional Scientific Programme Current to date: 18 March 2019 39th Congress of the EAPCCT Naples, 21 – 24 May 2019 Dioni & Elettra, Tuesday 21 May 2019 (morning) CONTINUING EDUCATION IN CLINICAL TOXICOLOGY Natural Toxin Poisoning in Europe: A Global Interaction Time Title Lecturer 09:00 - 09:30 From abroad to home: PC experience of Andreas Schaper, GIZ-Nord “exotic poisoning” Poisons Centre, University Medical Centre, Göttingen, Germany 09:30 - 10:00 The Red Sea and Mediterranean Sea Régis Bédry, University connection: the toxicological risks Hospital Bordeaux, France associated with the Suez Canal 10:00 - 10:30 Tetrodotoxism vs ciguatera Mark Little, Cairns Hospital, Cairns, Australia At the end of this session the audience should be able to: • explain toxicovigilance aspects of envenomations with exotic pets in Western Europe • know the conditions in which Red Sea's venomous marine animals can become a danger for people living around the Meditterranean Sea • describe the differences between tetrodotoxin and ciguatera syndromes, including mechanism of toxicity, sources of toxin, symptoms and signs and possible treatments 10:30 - 11:00 Coffee 11:00 - 11:30 Dangerous jellyfish in Europe - an Julian White, Women’s & overview for the toxicologist Children’s Hospital, Adelaide, Australia 11:30 - 12:00 Analytical strategies for determination of Carmela Dell’Aversano, palytoxins in the environment and in University of Napoli Federico seafood. Past present and future II, Naples, Italy challenges 12:00 - 12:30 Palytoxin and related compounds: new Luc de Haro, Hopital Sainte toxic guests in Europe Marguerite, Marseille, France 12:30 - 13:00 Snake venoms: actions and neutralization Bruno Lomonte, University of Costa Rica, San Jose At the end of this session the audience should be able to: • understand the relationship of jellyfish stings in European-region waters in comparison to stings in other regions and the potential for changes in risk secondary to climate change and how this might impact approaches to medical management • discuss the regulated and the emerging marine toxins that may affect humans through ingestion, dermal and aerosol contact and on the analytical techniques for their detection • list the different sources of palytoxin and related compounds and to describe the clinical features of exposure • understand the basics of snake venom toxic effects, their targets, and their neutralization by antivenoms 13:00 – 14:00 Lunch 3 Provisional Scientific Programme Current to date: 18 March 2019 39th Congress of the EAPCCT Naples, 21 – 24 May 2019 Dioni & Elettra, Tuesday 21 May 2019 (afternoon) CONTINUING EDUCATION IN CLINICAL TOXICOLOGY Natural Toxin Poisoning in Europe: A Global Interaction Time Title Lecturer 14:00 – 14:30 Toxicological syndromes linked to key Fabio Bucaretchi, State spiders and scorpions from South America University of Campinas, and their management Brazil 14:30 – 15:00 Anti-venom to treat scorpion stings: is it Bruno Mégarbane, Paris- useful? Diderot University, France 15:00 – 15:30 European, African and Middle East Snakes Miran Brvar, University and Snake Bites Medical Centre LjuBljana, Slovenia At the end of this session the audience should be able to: • recognize the main local and systemic features observed in patients bitten by spiders of the genera Phoneutria, Latrodectus and Loxosceles, and stung by Tityus spp. scorpions • understand the advantages versus the inconveniences in administering antivenom to a scorpion- envenomated patient • describe the features and management of snake bites in Europe, Northern Africa and Middle East 15:30 – 16:00 Coffee 16:00 – 16:30 Envenomation with snakes from the Jean-Philippe Chippaux, American continent Institut Pasteur / Center for Translational Science, Paris, France 16:30 – 17:00 Availability of 'exotic' antivenoms in Marieke Dijkman, Dutch Europe: a recurring proBlem Poisons Information Center, Utrecht, Netherlands 17:00 – 17:30 Conclusion and synthesis of the Julian White, Women’s & communications: the world of natural Children’s Hospital, Adelaide, toxin poisoning is moving Australia At the end of this session the audience should be able to: • describe the figure of snakebite incidence and severity in the Americas to improve the management of envenomations • explain causes of unreliable availability of 'exotic' antivenom 4 Provisional Scientific Programme Current to date: 18 March 2019 39th Congress of the EAPCCT Naples, 21 – 24 May 2019 Main Congress 22 to 24 May 2019 § Shortlisted for Taylor & Francis best scientific presentation award 5 Provisional Scientific Programme Current to date: 18 March 2019 39th Congress of the EAPCCT Naples, 21 – 24 May 2019 Galatea, Wednesday 22 May 2019 (morning) Welcome & Plenary Lecture Time Title Lecturer 09:00 – 09:05 Welcome and opening Martin Wilks President EAPCCT 09:05 – 09:55 Envenoming and related issues in Julian White, Women’s & Europe versus the rest of the world - Children’s Hospital, contemplating the future in the Adelaide, Australia context of the present At the end of this lecture the audience should be able to: • understand more fully the extent of envenoming and other toxin-induced diseases (TIDs) in Europe, both endemic and emerging exotic causes, and ways exposure to these TIDs may increase over time Cyanide and Smoke Inhalation Symposium 10:00 – 10:20 Challenges in the diagnosis of acute Christopher Holstege, cyanide poisoning University of Virginia School of Medicine, Charlottesville, United States 10:20 – 10:40 The role of the new cyanide Philippe A Haouzi, Penn antidotes State University College of Medicine, Hershey, United States At the end of this session the audience should be able to: • describe the challenges in the diagnosis of cyanide poisoning and the varied presentations encountered • understand how the different families of cyanide antidotes can be used during cyanide intoxication 10:40 – 11:15 Coffee and Authors with Posters 6 Provisional Scientific Programme Current to date: 18 March 2019 39th Congress of the EAPCCT Naples, 21 – 24 May 2019 Galatea, Wednesday 22 May 2019 (morning) Cyanide and Smoke Inhalation Symposium (continued) Time Title Lecturer 11:15 – 11:20 Analysis of 350 consecutive cases of Anita Ecolini 1, carBon monoxide (CO) poisoning: the Alessandro Zotto 1, Florentine experience (abstract no Angelo Rotulo 1, 001) Alessandra Ieri 2, Emanuela Masini 1, Guido Mannaioni 3, Francesco Gambassi 2 1 Department of NEUROFARBA, University of Florence, Italy; 2 Medical Toxicology Unit and Poison Control Center, Azienda Ospedaliero- Universitaria Careggi, Florence, Italy; 3 Neuroscience, Psychology, Drug Research and Child Health, Università degli Studi di Firenze, Florence, Italy 11:20 – 11:25 Correlation Between clinical signs Hanne Herbots, Greet and/or symptoms and Blood cyanide Dieltiens, kurt Anseeuw concentrations in victims of cyanide Emergency Medicine, poisoning (abstract no 002) ZNA StuivenBerg, Antwerp, Belgium 11:25 – 11:45 Inhalation exposure to toxic chemicals: Bronwen Jugg, Defence mechanisms and medical management Science and Technology Laboratory, SalisBury, United kingdom 11:45 – 12:05 Molecular targets in lung toxicology Dirk Steinritz, Bundeswehr Institute of Pharmacology and Toxicology, Munich, Germany 12:05 – 12:25 Volcano eruptions: what are the Alvin Bronstein, Hawaii consequences for acute and chronic Department of Health, lung injury Honolulu, United States 12:25 – 12:30 Discussion 7 Provisional Scientific Programme Current to date: 18 March 2019 39th Congress of the EAPCCT Naples, 21 – 24 May 2019 At the end of this session the audience should be able to: • describe the effects of toxic chemical inhalation exposure on the lungs and how this could be mitigated • describe emerging mechanistic targets in lung injury induced by inhalation of toxic compounds • describe four types of volcanic emissions that can produce human health effects 12:30 – 13:20 Lunch Authors with Posters and Poster Round 13:20 – 13:50 (poster numBers 013, 015, 051, 055, 063) 8 Provisional Scientific Programme Current to date: 18 March 2019 39th Congress of the EAPCCT Naples, 21 – 24 May 2019 Dioni & Elettra, Wednesday 22 May 2019 (morning) Co-morbidities in the Poisoned Patient Symposium Time Title Lecturer 10:00 – 10:20 The consequences and impact of chronic Darren Roberts, NSW renal impairment on acute poisoning Poisons Information Centre and St Vincent's Hospital, Sydney, Australia 10:20 – 10:40 The consequences and impact of chronic Stephen Krähenbühl, liver impairment on acute poisoning University Hospital Basel, Switzerland At the end of this session the audience should be able to: • understand the impact of chronic kidney disease on risk assessment in poisoned patients • understand the impact of liver cirrhosis on the kinetics and dynamics of toxicants 10:40 – 11:15 Coffee and Authors with Posters 11:15 – 11:35 The consequences and impact of co- Sergej Zacharov, Charles morBidities in the perspective of a toxic University, 1st Faculty of outbreak Medicine, and General University HospitalPrague, Czech RepuBlic 11:35 – 11:50 A consensus statement on the Hossein Hassanian- management of patients in outbreaks of Moghaddam 1, Nasim methanol poisoning (abstract no 003)