Supplementary Table I YbeA containing organisms with their taxonomy according to the NCBI Entrez Taxonomy Homepage (http://www.ncbi.nlm.nih.gov/sites/entrez?db=taxonomy) as of March 2008 as used in Figure 5 and Supplementary Figure 1. For every organism, its six- letter abbreviation, taxonomy from domain to species and link to protein database entry is listed. Abbreviation Domain Phylum Class Order Family Genus Species Link http://www.ncbi. Escherichia coli nlm.nih.gov/entr Gamma- Esccol Bacteria Proteobacteria Enterobacteriales Enterobacteriaceae Escherichia str. K-12 substr. ez/viewer.fcgi?d proteobacteria MG1655 b=protein&id=161 28619 http://www.ncbi. nlm.nih.gov/entr Gamma- Haemophilus Haeinf Bacteria Proteobacteria Pasteurellales Pasteurellaceae Haemophilus ez/viewer.fcgi?d proteobacteria influenzae Rd KW20 b=protein&id=162 72008 http://www.ncbi. Vibrio cholerae O1 nlm.nih.gov/entr Gamma- Vibcho Bacteria Proteobacteria Vibrionales Vibrionaceae Vibrio biovar eltor str. ez/viewer.fcgi?d proteobacteria N16961 b=protein&id=156 40967 http://www.ncbi. Alteromonas nlm.nih.gov/entr Gamma- Altmac Bacteria Proteobacteria Alteromonadales Alteromonadaceae Alteromonas macleodii 'Deep ez/viewer.fcgi?d proteobacteria ecotype' b=protein&id=887 96842 http://www.ncbi. nlm.nih.gov/entr Gamma- Idiomarina baltica Idibal Bacteria Proteobacteria Alteromonadales Idiomarinaceae Idiomarina ez/viewer.fcgi?d proteobacteria OS145 b=protein&id=857 13006 http://www.ncbi. nlm.nih.gov/entr Gamma- Pseudo- Pseudoalteromonas Psetun Bacteria Proteobacteria Alteromonadales Pseudoalteromonas ez/viewer.fcgi?d proteobacteria alteromonadaceae tunicata D2 b=protein&id=888 60569 http://www.ncbi. nlm.nih.gov/entr Gamma- Psychromonas sp. Psychromonas_sp Bacteria Proteobacteria Alteromonadales Psychromonadaceae Psychromonas ez/viewer.fcgi?d proteobacteria CNPT3 b=protein&id=904 07773 http://www.ncbi. nlm.nih.gov/entr Gamma- Moritella_sp Bacteria Proteobacteria Alteromonadales Moritellaceae Moritella Moritella sp. PE36 ez/viewer.fcgi?d proteobacteria b=protein&id=149 912298 http://www.ncbi. nlm.nih.gov/entr Gamma- Shewanella benthica Sheben Bacteria Proteobacteria Alteromonadales Shewanellaceae Shewanella ez/viewer.fcgi?d proteobacteria KT99 b=protein&id=163 752396 Abbreviation Domain Phylum Class Order Family Genus Species Link http://www.ncbi. nlm.nih.gov/entr Gamma- Acinetobacter Acibau Bacteria Proteobacteria Pseudomonadales Moraxellaceae Acinetobacter ez/viewer.fcgi?d proteobacteria baumannii AYE b=protein&id=169 796774 http://www.ncbi. nlm.nih.gov/entr Gamma- Pseudomonas Pseaer Bacteria Proteobacteria Pseudomonadales Pseudomonadaceae Pseudomonas ez/viewer.fcgi?d proteobacteria aeruginosa PAO1 b=protein&id=155 99199 http://www.ncbi. nlm.nih.gov/entr Gamma- Marinomonas sp. Marinomonas_sp Bacteria Proteobacteria Oceanospirillales Oceanospirillaceae Marinomonas ez/viewer.fcgi?d proteobacteria MED121 b=protein&id=871 19263 http://www.ncbi. nlm.nih.gov/entr Gamma- Hahella chejuensis Hahche Bacteria Proteobacteria Oceanospirillales Hahellaceae Hahella ez/viewer.fcgi?d proteobacteria KCTC 2396 b=protein&id=836 48484 http://www.ncbi. nlm.nih.gov/entr Gamma- Xylella fastidiosa Xylfas Bacteria Proteobacteria Xanthomonadales Xanthomonadaceae Xylella ez/viewer.fcgi?d proteobacteria 9a5c b=protein&id=158 36940 http://www.ncbi. Francisella nlm.nih.gov/entr Gamma- Fratul Bacteria Proteobacteria Thiotrichales Francisellaceae Francisella tularensis subsp. ez/viewer.fcgi?d proteobacteria holarctica FSC200 b=protein&id=167 009369 http://www.ncbi. nlm.nih.gov/entr Gamma- Ectothio- Nitrococcus mobilis Nitmob Bacteria Proteobacteria Chromatiales Nitrococcus ez/viewer.fcgi?d proteobacteria rhodospiraceae Nb-231 b=protein&id=888 11886 http://www.ncbi. nlm.nih.gov/entr Gamma- Reinekea_sp Bacteria Proteobacteria unclassified unclassified Reinekea Reinekea sp. MED297 ez/viewer.fcgi?d proteobacteria b=protein&id=888 01226 http://www.ncbi. nlm.nih.gov/entr Alpha- Roseobacter Roslit Bacteria Proteobacteria Rhodobacterales Rhodobacteracea Roseobacter ez/viewer.fcgi?d proteobacteria litoralis Och 149 b=protein&id=163 732522 Abbreviation Domain Phylum Class Order Family Genus Species Link http://www.ncbi. nlm.nih.gov/entr Alpha- Oceanicaulis Oceale Bacteria Proteobacteria Rhodobacterales Hyphomonadaceae Oceanicaulis ez/viewer.fcgi?d proteobacteria alexandrii HTCC2633 b=protein&id=839 44749 http://www.ncbi. nlm.nih.gov/entr Alpha- Agrobacterium Agrtum Bacteria Proteobacteria Rhizobiales Rhizobiaceae Agrobacterium ez/viewer.fcgi?d proteobacteria tumefaciens str. C58 b=protein&id=158 90025 http://www.ncbi. nlm.nih.gov/entr Alpha- Brucella melitensis Brumel Bacteria Proteobacteria Rhizobiales Brucellaceae Brucella ez/viewer.fcgi?d proteobacteria 16M b=protein&id=179 86495 http://www.ncbi. Methylobacterium nlm.nih.gov/entr Alpha- Methylo- Metrad Bacteria Proteobacteria Rhizobiales Methylobacterium radiotolerans JCM ez/viewer.fcgi?d proteobacteria bacteriaceae 2831 b=protein&id=170 746550 http://www.ncbi. nlm.nih.gov/entr Alpha- Rhodopseudomonas Rhopal Bacteria Proteobacteria Rhizobiales Bradyrhizobiaceae Rhodopseudomonas ez/viewer.fcgi?d proteobacteria palustris CGA009 b=protein&id=399 33244 http://www.ncbi. nlm.nih.gov/entr Alpha- Mesorhizobium loti Meslot Bacteria Proteobacteria Rhizobiales Phyllobacteriaceae Mesorhizobium ez/viewer.fcgi?d proteobacteria MAFF303099 b=protein&id=134 73414 http://www.ncbi. nlm.nih.gov/entr Alpha- Azorhizobium Azocau Bacteria Proteobacteria Rhizobiales Xanthobacteraceae Azorhizobium ez/viewer.fcgi?d proteobacteria caulinodans ORS 571 b=protein&id=158 425759 http://www.ncbi. nlm.nih.gov/entr Alpha- Aurantimonas sp. Aurantimonas_sp Bacteria Proteobacteria Rhizobiales Aurantimonadaceae Aurantimonas ez/viewer.fcgi?d proteobacteria SI85-9A1 b=protein&id=904 18829 http://www.ncbi. nlm.nih.gov/entr Alpha- Bartonella Barbac Bacteria Proteobacteria Rhizobiales Bartonellaceae Bartonella ez/viewer.fcgi?d proteobacteria bacilliformis KC583 b=protein&id=121 601669 Abbreviation Domain Phylum Class Order Family Genus Species Link http://www.ncbi. nlm.nih.gov/entr Alpha- Sphingopyxis Sphala Bacteria Proteobacteria Sphingomonadales Sphingomonadaceae Sphingopyxis ez/viewer.fcgi?d proteobacteria alaskensis RB2256 b=protein&id=103 486069 http://www.ncbi. nlm.nih.gov/entr Alpha- Erythrobacter Erylit Bacteria Proteobacteria Sphingomonadales Erythrobacteraceae Erythrobacter ez/viewer.fcgi?d proteobacteria litoralis HTCC2594 b=protein&id=853 75474 http://www.ncbi. nlm.nih.gov/entr Alpha- Rhodospirillum Rhorub Bacteria Proteobacteria Rhodospirillales Rhodospirillaceae Rhodospirillum ez/viewer.fcgi?d proteobacteria rubrum ATCC 11170 b=protein&id=835 92571 http://www.ncbi. nlm.nih.gov/entr Alpha- Acidiphilium cryptum Acicry Bacteria Proteobacteria Rhodospirillales Acetobacteraceae Acidiphilium ez/viewer.fcgi?d proteobacteria JF-5 b=protein&id=148 260549 http://www.ncbi. nlm.nih.gov/entr Alpha- Caulobacter Caucre Bacteria Proteobacteria Caulobacterales Caulobacteraceae Caulobacter ez/viewer.fcgi?d proteobacteria crescentus CB15 b=protein&id=161 27663 http://www.ncbi. nlm.nih.gov/entr Alpha- Parvularcula Parber Bacteria Proteobacteria Parvularculales Parvularculaceae Parvularcula ez/viewer.fcgi?d proteobacteria bermudensis HTCC2503 b=protein&id=847 02322 http://www.ncbi. nlm.nih.gov/entr Beta- Burkholderia dolosa Burdol Bacteria Proteobacteria Burkholderiales Burkholderiaceae Burkholderia ez/viewer.fcgi?d proteobacteria AUO158 b=protein&id=843 62417 http://www.ncbi. nlm.nih.gov/entr Beta- Neisseria Neimen Bacteria Proteobacteria Neisseriales Neisseriaceae Neisseria ez/viewer.fcgi?d proteobacteria meningitidis MC58 b=protein&id=156 77847 http://www.ncbi. nlm.nih.gov/entr Beta- Azoarcus_sp Bacteria Proteobacteria Rhodocyclales Rhodocyclaceae Azoarcus Azoarcus sp. BH72 ez/viewer.fcgi?d proteobacteria b=protein&id=119 899898 Abbreviation Domain Phylum Class Order Family Genus Species Link http://www.ncbi. nlm.nih.gov/entr Beta- Methylophilales Metbac Bacteria Proteobacteria Methylophilales unclassified unclassified ez/viewer.fcgi?d proteobacteria bacterium HTCC2181 b=protein&id=118 594491 http://www.ncbi. nlm.nih.gov/entr Beta- Nitrosomonas Niteur Bacteria Proteobacteria Nitrosomonadales Nitrosomonadaceae Nitrosomonas ez/viewer.fcgi?d proteobacteria europaea ATCC 19718 b=protein&id=302 48374 http://www.ncbi. Campylobacter jejuni nlm.nih.gov/entr Epsilon- Camjej Bacteria Proteobacteria Campylobacterales Campylobacteraceae Campylobacter subsp. jejuni NCTC ez/viewer.fcgi?d proteobacteria 11168 b=protein&id=157 91514 http://www.ncbi. nlm.nih.gov/entr Epsilon- Helicobacter pylori Helpyl Bacteria Proteobacteria Campylobacterales Helicobacteraceae Helicobacter ez/viewer.fcgi?d proteobacteria 26695 b=protein&id=156 45565 http://www.ncbi. nlm.nih.gov/entr Epsilon- Caminibacter Cammed Bacteria Proteobacteria Nautiliales Nautiliaceae Caminibacter ez/viewer.fcgi?d proteobacteria mediatlanticus TB-2 b=protein&id=149 194759 http://www.ncbi. nlm.nih.gov/entr Delta- Bdellovibrio Bdebac Bacteria Proteobacteria Bdellovibrionales Bdellovibrionaceae Bdellovibrio ez/viewer.fcgi?d proteobacteria bacteriovorus HD100 b=protein&id=425 25168 http://www.ncbi. nlm.nih.gov/entr Delta- Desulfuro- Geobacter Geoura Bacteria Proteobacteria Geobacteraceae Geobacter ez/viewer.fcgi?d proteobacteria monadales uraniireducens Rf4 b=protein&id=148 266138 http://www.ncbi. nlm.nih.gov/entr Delta- Desulfuro- Pelobacter Pelpro Bacteria Proteobacteria Pelobacteraceae Pelobacter ez/viewer.fcgi?d proteobacteria monadales propionicus DSM 2379