Gezondheidsraad Voorzitter Health Council of the Netherlands Aan de Staatssecretaris van Sociale Zaken en Werkgelegenheid Onderwerp : Aanbieding adviezen herevaluatie bestuurlijke MAC-waarden Uw kenmerk : ARBO/AMIL/97/00648 Ons kenmerk : U 2204/CB/mj/563-B5 Bijlagen : 1 Datum : 13 november 2001 Mijnheer de staatssecretaris, Op verzoek van uw ambtsvoorganger bied ik u hierbij 12 adviezen aan van een reeks over de gezondheidskundige basis van uit het buitenland overgenomen grenswaarden voor beroepsmatige blootstelling aan stoffen. Het verzoek om deze adviezen is in algemene zin vervat in brief nr ARBO/AMIL/97/00648 en in latere stadia door uw departement toegespitst op afzonderlijke stoffen. De adviezen zijn opgesteld door een daartoe door mij geformeerde internationale commissie van de Gezondheidsraad en beoordeeld door de Beraadsgroep Gezondheid en Omgeving. De beoogde reeks van in het Engels gestelde adviezen zal losbladig worden gepubliceerd onder ons publicatienummer 2000/15OSH en, conform de aan de Gezondheidsraad voorgelegde toespitsingen van de adviesaanvraag, betrekking hebben op 168 stoffen. Het u thans aangeboden tweede pakket bestaat uit de adviezen genummerd 2000/15OSH/018 tot en met 2000/15OSH/029, respectievelijk betrekking hebbend op: bornanon-2 (kamfer, synthetisch), chloortrifluoride, o-chloorstyreen, cyclohexylamine, dizwaveldecafluoride, hexafluoroaceton, keteen, pentachloornaftaleen, perchlorylfluoride, m-ftalodinitril, thionylchloride en trichloornaftaleen. Bij afronding van de werkzaamheden van de hierboven bedoelde commissie ontvangt u een Nederlandstalige samenvatting van de in de gehele reeks van adviezen neergelegde bevindingen. Bezoekadres Postadres Parnassusplein 5 Postbus 16052 2511 VX Den Haag 2500 BB Den Haag Telefoon (070) 340 75 20/6779 Telefax (070) 340 75 23 Gezondheidsraad Voorzitter Health Council of the Netherlands Onderwerp : Herevaluatie uit het buitenland overgenomen grenswaarden Ons kenmerk : U 2204/CB/mj/563-B5 Pagina : 2 Datum : 13 november 2001 De u thans aangeboden adviezen heb ik vandaag ter informatie doen toekomen aan de Minister van Volksgezondheid, Welzijn en Sport en aan de Minister van Volkshuisvesting, Ruimtelijke Ordening en Milieubeheer. Hoogachtend, prof. dr JA Knottnerus Bezoekadres Postadres Parnassusplein 5 Postbus 16052 2511 VX Den Haag 2500 BB Den Haag Telefoon (070) 340 75 20/6779 Telefax (070) 340 75 23 Health-based Reassessment of Administrative Occupational Exposure Limits Health-based Reassessment of Administrative Occupational Exposure Limits Committee on Updating of Occupational Exposure Limits, a committee of the Health Council of the Netherlands No. 2000/15OSH, The Hague, 14 December 2000 \ The Health Council of the Netherlands, established in 1902, is an independent scientific advisory body. Its remit is “to advise the government and Parliament on the current level of knowledge with respect to public health issues...” (Section 21, Health Act). The Health Council receives most requests for advice from the Ministers of Health, Welfare & Sport, Housing, Spatial Planning & the Environment, Social Affairs & Employment, and Agriculture, Nature Preservation & Fisheries. The Council can publish advisory reports on its own initiative. It usually does this in order to ask attention for developments or trends that are thought to be relevant to government policy. Most Health Council reports are prepared by multidisciplinary committees of Dutch or, sometimes, foreign experts, appointed in a personal capacity. The reports are available to the public. Preferred citation: Health Council of the Netherlands: Committee on Updating of Occupational Exposure Limits. Health-based Reassessment of Administrative Occupational Exposure Limits; The Hague: Health Council of the Netherlands, 2000; publication no. 2000/15OSH. all rights reserved ISBN: 90-5549-350-3 Contents page 2000/15OSH General remarks 000-1 General introduction 000-3 The committee 000-7 Default values 000-9 Abbreviations 000-11 Name of substance [CAS reg. nr] acetic acid [64-19-7] aluminium alkyl compounds [96-10-6; 97-93-8;100-99-2; 563-43-9] aluminium pyro powder 2-aminopyridine [504-29-0] ammonium chloride (fume) [12125-02-9] benomyl [17804-35-2] benzenethiol (phenyl mercaptan) [108-98-5] biphenyl/diphenyl ether mixture [92-52-4; 101-84-8; 8004-13-5] bismuth telluride [1304-82-1] bornan-2-one (camphor, synthetic) [76-22-2] 018-1 boron oxide [1303-86-2] 5 Contents boron trifluoride [7637-07-2] bromine [7726-95-6] n-butane [106-97-8] butanethiol (butyl mercaptan) [109-79-5] n-butylamine [109-73-9] o-sec-butylphenol [89-72-5] p-tert-butyltoluene [98-51-1] calcium carbonate [1317-65-3] calcium hydroxide [1305-62-0] calcium oxide [1305-78-8] calcium sulphate [7778-18-9; 10101-41-4] carbon tetrabromide [558-13-4] cellulose [9004-34-6] cesium hydroxide [21351-79-1] 001-1 chlorine trifluoride [7790-91-2] 019-1 2-chloroacetophenone [532-27-4] o-chlorobenzylidene malonitrile [2698-41-1] 1-chloro-1-nitropropane [600-25-9] o-chlorostyrene [2039-87-4] 020-1 o-chlorotoluene [95-49-8] chlorpyrifos [2921-88-2] chlorinated diphenyl oxides clopidol [2971-90-6] cyanamide and calcium cyanamide [420-04-2; 156-62-7] cyanogen chloride [506-77-4] cyclohexene [110-83-8] cyclohexylamine [108-91-8] 021-1 cyclopentane [287-92-3] 002-1 demeton [8065-48-3] diborane [19287-45-7] 003-1 dibutyl phosphate [107-66-4] 1,3-dichloro-5,5-dimethyl hydantoin [118-52-5] 1,1-dichloro-1-nitroethane [594-72-9] dicrotophos [141-66-2] diethylene triamine (DETA) [111-40-0] diethyl ketone [96-22-0] 6 Health-based Reassessment of Administrative Occupational Exposure Limits diisopropylamine [108-18-9] dimethoxymethane (methylal) [109-87-5] 004-1 N,N-dimethylethylamine [598-56-31] dioxathion [78-34-2] dipropyl ketone [123-19-3] disodium tetraborates and boric acid [1303-96-4; 1330-43-4; 11130-12-4; 10043-35-3] disulfoton [298-04-4] disulfur dichloride (sulfur monochloride) [10025-67-9] disulfur decafluoride (sulfur pentachloride) [5714-22-7] 022-1 2,6-di-tert-butyl-4-methoxyphenol (2,6-di-tert-butyl-p-cresol) [128-37-0] divinyl benzene [91-14-5; 105-06-6; 108-57-6; 1321-74-0] ethanethiol (ethyl mercaptan) [75-08-1] ethylene glycol dinitrate (EGDN) [628-96-6] ethyl formate [109-94-4] N-ethylmorpholine [100-74-3] ferric oxide (rouge) [1309-37-1] formic acid [64-18-6] germanium tetrahydride [7782-65-2] 006-1 glycerol trinitrate (nitroglycerin) [55-63-0] hexachlorocyclopentadiene [77-47-4] hexachloronaphthalene [1335-87-1] 007-1 hexafluoroacetone [684-16-2] 023-1 hexogen [121-82-4] sec-hexyl acetate [108-84-9] 2-hydroxypropyl acrylate [999-61-1] 2,2’-iminodiethanol [111-42-2] indene [95-13-6] iron pentacarbonyl [13463-40-6] iron salts, dicyclopentadiene [102-54-5] iron salts, water-soluble [7705-08-0; 7720-78-7; 7758-94-3; 10028-22-5; 10421-48-4] isoamyl alcohol [123-51-3] isooctyl alcohol (mixed isomers) [26952-21-6] isopropylamine [75-31-0] N-isopropylaniline [768-52-5] 7 Contents ketene [463-51-4] 024-1 liquefied petroleum gas (L.P.G.) [68476-85-7] magnesium carbonate [546-93-0] magnesium oxide (fume) [1309-48-4] MAPP gas (methyl acetylene-propadiene mixture) [59355-75-8] mesityl oxide [141-79-7] methanethiol (methyl mercaptan) [74-93-1] 008-1 methyl acetate [79-20-9] methyl acetylene [74-99-7] methylcyclohexane [108-87-2] methylcyclohexanol [25639-42-3] 010-1 o-methylcyclohexanone [583-60-8] methyl demeton [8022-00-2] methyl ethyl ketone peroxide [1338-23-4] methyl isopropyl ketone [563-80-4] 009-1 mica [12001-26-2] 011-1 monocrotophos [6923-22-4] naled [300-76-5] nicotine [54-11-5] nitrapyrin ((2-chloro-6-trichloromethyl)-pyridine) [1929-82-4] nitric oxide [10102-43-9] nitroethane [79-24-3] nitrogen trifluoride [7783-54-2] m-nitrotoluene [99-08-1] nonane [111-84-2] octachloronaphthalene [2234-13-1] 012-1 n-octane [111-65-9] osmium tetraoxide [20816-12-0] oxalic acid [144-62-7] oxalonitrile (cyanogen) [460-19-5] oxygen difluoride [7783-41-7] paraffin wax (fume) [8002-74-2] pentachloronaphthalene [1321-64-8] 025-1 2-pentanone (methyl propyl ketone) [107-87-9] perchloromethyl mercaptan [594-42-3] perchloryl fluoride [7616-94-6] 026-1 8 Health-based Reassessment of Administrative Occupational Exposure Limits perlite [8075-36-3; 93763-70-3] phenothiazine [92-84-2] phenylphosphine [638-21-1] 013-1 2-phenylpropene (a-methyl styrene) [98-83-9] phorate [298-02-2] m-phthalodinitrile [626-17-5] 027-1 pindone (2-pivalyl-1,3-indandione) [83-26-1] potassium hydroxide [1310-58-3] propargyl alcohol [107-19-7] n-propyl nitrate [627-13-4] pyrethrum [8003-34-7] resorcinol [108-46-3] rotenone [83-79-4] saccharose (sucrose) [57-50-1] silane (silicon tetrahydride) [7803-62-5] 014-1 silicon [7440-21-3] slate dust soapstone [14378-12-2] sodium bisulfite [7631-90-5] sodium hydroxide [1310-73-2] 015-1 starch [9005-84-9; 9005-84-9] strychnine [57-24-9] sulfur tetrafluoride [7783-60-0] sulfuryl fluoride [2699-79-8] tantalum [7440-25-7] tellurium and tellurium compounds [13494-80-9] tellurium hexafluoride [7783-80-4] temephos [3383-96-8] o,m,p-terphenyl (mixture) [26140-60-3] tetrachloronaphthalene [1335-88-2] 016-1 tetraethyl orthosilicate (ethyl silicate) [78-10-4] tetramethyl orthosilicate (methyl silicate) [681-84-5] tetramethyl succinonitrile [3333-52-6] tetramethyl thiuram disulfide (thiram) [137-26-8] thallium and water-soluble thallium compounds [7440-28-0] 4,4’-thiobis (6-tert-butyl-m-cresol) [96-69-5] 9 Contents thionyl chloride [7719-09-7] 028-1 tin oxide [18282-10-5; 21651-19-4] titanium dioxide [13463-67-7] tributyl phosphate [126-73-8] tricarbonyl (eta -cyclopentadienyl)