Proceeding Book The 18th National Congress & Annual Scientific Meeting Indonesian Association of Pathologist 2015 Diagnostic Challenges and Updates in Gastrointestinal & Liver Pathology in conjunction with APSMI Annual Meeting 2015 Molecular Pathology & Clinical Updates Hotel Tentrem, 20-22 November 2015 UGM Press 2015 Proceeding Book The 18th National Congress & Annual Scientific Meeting Indonesian Association of Pathologist 2015 Diagnostic Challenges and Updates in Gastrointestinal & Liver Pathology in conjunction with APSMI Annual Meeting 2015 Molecular Pathology & Clinical Updates Hotel Tentrem, 20-22 November 2015 Editors dr. Harijadi, Sp.PA (K) dr, Irianiwati, Sp.PA (K) dr. Hanggoro Tri Rinonce, Sp.PA, PhD dr. Brian Wasita, PhD dr. Novan Adi Setiawan dr. Intannuary Paringga Copyright ©2015 UGM Press Perpustakaan Nasional: Katalog Dalam Terbitan (KDT) ISBN 978-602-386-023-4 First edition, 2015 Publisher: UGM Press Jl. 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This work may not be translated or copied in whole or in part without the written permission of the publisher TABLE OF CONTENT Cover .................................................................................................................................................... 1 Table of Content .............................................................................................................................................. 3 Welcome Remarks by the Chairman of the 18th National Congress and Annual Scientific Meeting (ASM) of Indonesian Association of Pathologists 2015 ........................................................ 9 Wellcome Remarks by the Chairman of APSMI 2015 ...................................................................... 10 Programme ........................................................................................................................................... 11 Short Biography and Abstract and of the 18th National Congress and Annual Scientific Meeting (ASM) of Indonesian Association of Pathologists 2015 Speakers S1. Mesenchymal Tumors of the Gastrointestinal Tract (Samir S Amr) ........................................... 16 S2. Gastrointestinal Stromal Tumor (J. Bras) .................................................................................... 21 S3. Malignant Pediatric Liver Tumors of Hepatocellular Origin (J. Bras) .......................................... 22 S4. New Classification of Liver Neoplasm (Swan Tung) ................................................................... 29 S5. Recent Advances in Liver Disease: Pathology Aspect (Swan Thung) ....................................... 31 S6. Liver Transplantation: Histopathology of Late Allograft Rejection (Hironori Haga) .................... 35 S7. Clinical Aspects of Liver Diseases in Children (Nenny Sri Mulyani) ........................................... 36 S8. Pathological Aspect of Liver Biopsy (Ening Krisnuhoni) ............................................................. 38 S9. Pathological Aspect of Liver Neoplasia (Shinichi Aishima) ......................................................... 41 S10. Molecular Update in Liver Disease (Shinichi Aishima) ............................................................... 42 S11. Cytological Aspect of Liver Neoplasia (Aileen Wee) ................................................................... 47 S12. Cytology of nonneoplastic lesions in the liver (Aileen Wee) ....................................................... 48 S13. Epithelial Neoplasms of the GI Tract (Marian Priyanthi Kumarasinghe) .................................... 51 S14. Molecular Pathology of Epithelial Tumors of the GI Tract (Marian Priyanthi Kumarasinghe) .... 52 S15. The Clinical Aspects of Gastrointestinal Biopsy (Putut Bayupurnama) ...................................... 55 S16. HER2 Testing in Gastric Cancer (Ahmad Ghozali) ..................................................................... 58 S17. Integrating Biomarkers into Pathological Aspect in Gastrointestinal Tumor: Focusing on Molecular Pathology Experienced in Yogyakarta (Didik Setyo Heriyanto) ................................. 60 S18. Extended RAS Testing in Metastatic Colorectal Cancer Patients: RSCM’s Experiences (Nur Rahadiani) ................................................................................................................................... 62 S19. Polyp Lesions of the GI Tract: The Role of Pathologist in Risk Assessment of Precursor Malignant Polyps (Diah Rini Handjari) ........................................................................................ 64 Short Biography of Moderators Harijadi .................................................................................................................................................. 65 Totok Utoro ............................................................................................................................................ 66 Ambar Mudigdo ..................................................................................................................................... 67 FX Ediati Triningsih ............................................................................................................................... 69 Abstract of Oral Presentation O1. The Effects of Red Fruit Extract (Pandanus conoideus lam) on Male White Rats Wistar (Rattus norvegicus) Liver Histopathologic Feature Induced by High Dose of Paracetamol (Eva Pravitasari Nefertiti) ............................................................................................................ 70 O2. Involvement of Nuclear Localization of NFATc1 in Initiation and Maintenance of B-Cell Lymphomas (Krisna Murti) .......................................................................................................... 71 O3. Protein Regenerating Liver-3 (PRL-3) Up Regulated the Expression of MMP2 and Down Regulated the expression of e-cadherin in colorectal cancer (Upik Anderiani Miskad) ............. 72 O4. Detection of Hirschprung’s Disease rrom Rectal Suction Biopsy Specimen with Acetylcholinesterase Enzyme Histochemistry Technique (Willy Sandhika) ............................... 73 O5. Phyllodes Tumour of the Breast: Clinicopathologic and Recurrence Analysis of 63 Patients (Fairuz) ........................................................................................................................................ 74 O6. The Different Expression of Matrix Metalloproteinase-2 in High and Low Grade Malignant Peripheral Nerve Sheath Tumor and Its Correlation with Prognostic Factors (Niniek Hardini) .. 75 O7. Endothelin-1/Endothelin A Receptor Axis Correlates with Heparanase Expression in Ovarian Carcinoma (Nungki Anggorowati) ............................................................................................... 76 O8. Molecular Study of Prognostic Markers of Serous Epithelial Ovarian Carcinoma in Indonesian Woman (Aswiyanti Asri) ........................................................................................... 77 O9. Expression of CXCR4 Gene as Unfavourable Prognosis Markers in Breast Carcinoma (Novan Adi Setyawan) ................................................................................................................ 78 O10. Correlation Between Heparanase Expression and Diffuse Large B Cell Lymphoma (DLBCL) Variant Centroblastic and Immunoblastic (Auliya Suluk Brilliant Sumpono) ............................... 79 3 O11. The Expression of IL-4 and IFN-γ In Aspirate of Tuberculous Lymphadenitis Showing Dark Specks and Dark Oval Bodies (Humairah Medina Liza Lubis) ................................................... 80 O12. The Expresion of Interleukin-10 on Breast Carcinoma: A Histopathological Based Study (Sigit Wijanarko) .......................................................................................................................... 81 O13. Expression of Ezrin and CD 44 in Osteosarcoma (Christian Bambang Sulistio) ........................ 82 O14. Increased EMMPRIN Immunoexpresion in Urothelial Carcinoma Infiltrating and Non Infiltrating of The Bladder (Agus Koesmawan) ........................................................................... 83 O15. The Difference Between p53 and Progesteron Receptor Expression in Meningiomas on Dr. Kariadi Hospital (Edy Prasetyo) .................................................................................................. 84 O16. Analysis Correlations of SOX2 and p63 Expression on Basal-Like and Non Basal-Like Breast Cancer (Reno Keumalazia Kamarlis) .......................................................................................... 85 O17. Association H-Ras Mutation in Exon 2,3 and 4 with Histopathologic Type in Bladder Urothelial Carcinoma (Ris Kristiana) ........................................................................................... 86 O18. The Difference between Progesteron Receptor and Ki-67 Expression in Meningiomas on Dr. Kariadi Hospital (Raudatul Janah) .............................................................................................. 87 O19. The Expression of NFkB/p65 and HIF-1α on Papillary Carcinoma Thyroid and Follicular Carcinoma Thyroid (Dian Eskaningrum) ..................................................................................... 88 O20. Relation of Immunoexpression LGR5 with Chemotherapy Response in Colorectal Adenocarcinoma (Sri Dharmayanti) ...........................................................................................