Marc Van Montagu and Jeff

Marc Van Montagu and Jeff

Ghent: The Cradle of Plant Biotechnology – From ’70s-now: UGent: one of the leading research centers in plant science – Early ’80s: Marc Van Montagu and Jeff Schell develop Agrobacterium-mediated transformation – 1982-1983: Marc Van Montagu founded Plant Genetic Systems (“PGS”), one of the agbiotech pioneers PGS: A Strong Track Record of Innovations – 1985: PGS develops the first insect-resistant plant – 1987: PGS develops herbicide-tolerance (“glufosinate-tolerance”) in plants – 1990: PGS develops molecular crop hybridization in canola PGS and VIB: Instrumental for Future Growth of Plant Biotech – 1996: Acquisition of PGS by AgrEvo Hoechst (now Bayer CropScience) – 1997: VIB founds DevGen - IPO in 2005 – 1998: VIB (Dirk Inzé) together with ex-PGS employee found CropDesign – Acquired by BASF in 2006 CropDesign: A Snapshot . Located in Ghent, Belgium; 110 employees . Founded in 1998 as a spin-off from VIB . A BASF Plant Science group company since June 2006 . Specialized in development of crop productivity traits by operating a unique rice-based high throughput trait discovery platform (“TraitMill”) . Focus is on rice as a model plant for corn and other cereals as well as a commercial crop TraitMillTM : Trait Development for Different High-Value Opportunities Productivity traits for Rice with Other BPS crops established field improved yield projects crops BASF BASF Annual Product leads throughput BASF Patent filing >60 validated leads Data mgt & analysis 10s of terabytes Plant phenotyping 150,000 plants Molecular analysis 350,000 PCRs Plant transformation >80,000 transformants Vector construction 1,300 constructs Gene selection 1,000s genes Genes Largest Crop-Based Discovery Platform for Yield Traits Automated Plant Evaluation System Leaf and panicle analysis Seed analysis Root analysis Broad and Diversified Pipeline of Lead Genes Higher seed count Larger seeds Larger panicles Control CD Control CD Control CD Increased green biomass Increased root biomass +20% Control CD Control CD A Growing Cluster CIE1 PIONEER CIE2 SOLUCEL CROPDESIGN BASF MONSANTO MONSANTO FMC DEVGEN BAYER CROPSCIENCE PIONEER SYNGENTA 2010: Major Global Hub for Plant Biotechnology – Together with Research Triangle Park (NC, US) THE major hub for agricultural biotechnology – VIB-PSB: world leading research center in plant science – Unique mix of academia, major players (Bayer, BASF) and start-ups – “Recycling” entrepeneurs – 800 researchers Gent Technology Park Largest European Cluster in Green Biotechnology .

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