2021-09-06 CURRICULUM VITAE Karl W. Broman Department of Biostatistics and Medical Informatics School of Medicine and Public Health niversit" of Wisconsin$Madison 2126 %enetics-Biotechnolo&" 'enter (2) Henr" Mall Madison* #isconsin )+,06 Phone- 60.-262-(6++ /mail- [email protected] Web: https://kbroman.org 01'ID- 0000-0002-(91(-66,1 EDUCATION 199, $ 1999 Postdoctoral 2ello3* 'enter for Medical %enetics* Marsh4eld Medical 1esearch 2oundation* Marsh4eld* Wisconsin 56d!isor- 7ames 89 Weber: 199, PhD* Statistics* niversit" of 'alifornia* Ber;ele" 56dvisor- Terr" Speed= thesis- Identifying quantitative trait loci in experimental crosses: 1991 BS* Summa Cum Laude* Mathematics* niversit" of Wisconsin$Mil3au;ee PROFESSIONAL POSITIONS 2009 $ present Professor* Department of Biostatistics and Medical Informatics* School of Medicine and Public Health* niversit" of Wisconsin$Madison 200, $ 2009 6ssociate Professor* Department of Biostatistics and Medical Informatics* School of Medicine and Public Health* niversit" of Wisconsin$Madison 2002 $ 200, 6ssociate Professor* Department of Biostatistics* Bloomber& School of Public Health* The 7ohns Hopkins niversit"* Baltimore* Mar"land 1999 $ 2002 6ssistant Professor* Department of Biostatistics* Bloomber& School of Public Health* The 7ohns Hopkins niversit"* Baltimore* Mar"land 1999 6ssociate 1esearch Scientist* 'enter for Medical %enetics* Marsh4eld Medical 1esearch 2oundation* Marsh4eld* Wisconsin ADDITIONAL PROFESSIONAL APPOINTMENTS 6>liate facult" member* Department of Statistics* ni!ersit" of Wisconsin$Madison 2acult" trainer* Biostatistics <rainin& Pro&ram* 'ellular and Molecular Patholo&" %raduate Pro&ram* 'omputation and Informatics in Biolo&" and Medicine Trainin& Pro&ram* %enetics PhD Pro&ram* %enomic Sciences Trainin& Pro&ram* Master of Public Health Pro&ram* Plant Breedin& and Plant %enetics Pro&ram* and Population Health %raduate Pro&ram* niversit" of Wisconsin$Madison 2 RESEARCH INTERESTS M" research concerns statistical issues arisin& in problems in &enetics and &enomics9 I focus particularl" on the characteri?ation of meiotic recombination and the de!elopment of impro!ed methods for detectin& and identif"in& &enes contributin& to variation in comple@ phenot"pes in e@perimental or&anisms9 SCIENTIFIC ADVISORY BOARDS 2009 $ 2016 Nature Source %enetics* Ithaca* Ne3 Bor; 2010 $ 2011 Wisconsin %enomics Initiative HONORS AND AWARDS 2ello3 of the 6merican Statistical 6ssociation 52016: %raduate of the 8ast Decade 63ard* niversit" of Wisconsin$Mil3au;ee 6lumni 6ssociation 52001: Best Paper in Genetic Epidemiology in 1999* International %enetic /pidemiolo&" Societ" 52000: 7ohn Wasmuth 2ello3ship in %enomic 6nal"sis* National Human %enome 1esearch Institute 5199.: /!el"n 2i@ Pri?e for &reat promise in statistical research* niversit" of 'alifornia* Ber;ele" 5199,: 0utstandin& %raduate Student Instructor* niversit" of 'alifornia* Ber;ele" 5199,: niversit" 2ello3ship, ni!ersit" of 'alifornia* Ber;ele" 5199(: Phi Beta Cappa Societ" 51991: %eneral 'hemistr" 63ard* niversit" of Wisconsin$Mil3au;ee 519.9: Wisconsin 6ll-State Scholar 519..: PROFESSIONAL SOCIETY MEMBERSHIPS 6merican 6ssociation of niversit" Professors 6merican Statistical 6ssociation %enetics Societ" of 6merica Institute of Mathematical Statistics International Biometric Societ" 5/A61: EDITORIAL ACTIVITIES Editorial Board Membership 2016 $ 2021 Senior /ditor* Genetics 2016 $ 2021 /ditorial Board* BMC Biology 201, $ 2019 6cademic /ditor* PeerJ 200( $ 2010 6ssociate /ditor* Genetics 2006 2009 6ssociate /ditor* Journal of t!e American Statistical Association* 6pplications and 'ase Studies 200( $ 200, 6ssociate /ditor* Biostatistics Peer Review Activities #eferee for 6merican 7ournal of /pidemiolo&"= 6merican 7ournal of Human %enetics= 6merican + Statistician= 6nnals of 6pplied Statistics= 6nnals of Human %enetics= 6nnals of Statistics= 6rteriosclerosis* <hrombosis* and Vascular Biolo&"= Bioinformatics= Biometrics= Biostatistics= BM' Bioinformatics= BM' Biolo&"= BM' %enetics= BM' %enomics= BM' Medical 1esearch Methodolo&"= BM' Proceedin&s= BM' 1esearch Notes= 'ancer 1esearch= 'irculation 1esearch= 'omputational Statistics E Data 6nal"sis= 'rop Science= e8ife= /uropean 7ournal of Human %enetics= /volution= %+ 5Bethesda:= %ene= %enes* Brain* and Beha!ior= %enes E Immunit"= %enetic /pidemiolo&"= %enetica= %enetical 1esearch= %enetics= %enetics 1esearch= %enetics Selection /volution= %enome= %enome 1esearch= %enomics= %ro3th* Development* E 6&in&= Harvard Data Science 1evie3= Heredit"= Human %enetics= Human Heredit"= Human Molecular %enetics= IE//F6'M Transactions on 'omputational Biolo&" and Bioinformatics= 7ournal of 6&ricultural* Biolo&ical* and /nvironmental Statistics= 7ournal of the 6merican Societ" of Nephrolo&"= 7ournal of the 6merican Statistical 6ssociation= 7ournal of 6pplied %enetics= 7ournal of Bioinformatics and 'omputational Biolo&"= 7ournal of 'omputational and %raphical Statistics= 7ournal of 2ish Biolo&"= 7ournal of Heredit"= 7ournal of Immunolo&"= 7ournal of Neuroscience= 7ournal of 0pen Source Soft3are= 7ournal of Statistical Distributions and 6pplications= 7ournal of Statistical Plannin& and Inference= 7ournal of Statistical Soft3are= Mammalian %enome= Methods in /colo&" and /!olution= Molecular Biolo&" and /!olution= Molecular /colo&" 1esources= Molecular %enetics and %enomics= Molecular Informatics= Nature 'ommunications= Aature %enetics= Aature Methods= Aature Protocols= Nature 1evie3s$%enetics= Nucleic 6cids 1esearch= 0phthalmic /pidemiolo&"= Paci4c S"mposium on Biocomputin&= Ph"sical 1evie3 8etters= Ph"siolo&ical %enomics= Plant 'ell= Plant Ph"siolo&"= P8oS Biolo&"= P8oS 'omputational Biolo&"= P8oS %enetics= P8oS 0A/= Proceedin&s of the National 6cadem" of Sciences S6= 1 7ournal= Scandinavian 7ournal of Immunolo&"= Science= Statistical 6pplications in %enetics and Molecular Biolo&"= Statistics= Theoretical Population Biolo&"= and Trends in %enetics Boo$ reviewer for 6rnold Publishers* 'hapman E HallF'1'* 'olumbia niversit" Press* 0@ford niversit" Press* Princeton niversit" Press* Sprin&er$Verla&* and <a"lor E 2rancis Review Panels 2010 $ 201) 'enter for Inherited Disease 1esearch 5'ID1: 6ccess 'ommittee* Aational Human %enome 1esearch Institute* National Institutes of Health 5C!air* 201( $ 201): 2006 $ 2010 %enomics* 'omputational Biolo&"* and Technolo&" Stud" Section 5%'6<:* 'enter for Scienti4c 1evie3* National Institutes of Health Ad hoc Review of Proposals 'enter for Inherited Disease 1esearch 6ccess 'ommittee= 'linical 1esearch 1evie3 'ommittee* Aational 'enter for 1esearch 1esources= %enomics* 'omputational Biolo&"* and Technolo&" Stud" Section 5AIH:= Hatch &rant competition* 'olle&e of 6&riculture and 8ife Sciences* niversit" of Wisconsin$Madison= 7ohns Hopkins 'enter for 6lternatives to 6nimal Testin&= Mammalian %enetics Stud" Section 5NIH:= Microsoft 1esearch /uropean 2ello3ship Pro&ramme= National 'ancer Institute Special /mphasis Panel 5NIH:= National Institute of /nvironmental Health Sciences Special /mphasis Panel 5AIH:= National Institute on 6&in& Special /mphasis Panel 5NIH:= Aational Science 'ouncil 51epublic of 'hina:= National Science 2oundation= National Sciences and /n&ineerin& 1esearch 'ouncil 5'anada:= 'ouncil for /arth and 8ife Sciences* Netherlands 0r&ani?ation for Scienti4c 1esearch= Neurolo&ical Sciences and Disorders 6 Stud" Section 5AIH:= and Telethon 5Ital": PUBLICATIONS Boo s Broman KW* Sen G 52009: A Guide to &'L Mapping wit! #(qtl) Sprin&er 5ISBA- 9,.-0-+.,-9212(-2: ( !o"rnal Articles 8obo 6C* Trae&er 88* Celler MP* 6ttie 6D* 1e" 2/* Broman KW 52021: Identi4cation of sample mi@-ups and mi@tures in microbiome data in Diversit" 0utbred mice9 G3 +Bet!esda,* to appear <rotter '* Cim H* 2ara&e %* Prins P* Williams 1#* Broman KW* Sen G 52021: Speedin& up eH<8 scans in the BID population usin& %P s9 G3 +Bet!esda,* to appear -.-/ <ran H* Broman KW 52021: <reatment of the I chromosome in mappin& multiple Juantitative trait loci9 G* +Bet!esda, 11-K;ab00) doi-109109+F&+KournalFK;ab00) Hassold <* Ma"lor-Ha&en H* Wood 6* %ruhn 7* HoLmann /* Broman KW* Hunt P 52021: 2ailure to recombine is a common feature of human oo&enesis9 Am J 0um Genet 10.-16$2( doi-10F&m)6 -.-. 8in;e D* 0verm"er C6* Miller IJ* Brademan D1* Hutchins PD* TruKillo /6* 1edd" <1* 1ussell 7D* 'ushin& /M* Schueler D8* Stapleton DS* 1aba&lia M/* Celler MP* %atti DM* Ceele %1* Pham D* Broman KW* 'hurchill %6* 6ttie 6D* 'oon 77 52020: 6 lar&e-scale &enome-lipid association map &uides lipid identi4cation9 1at Meta2 2-11(9$1162 doi-10F&;)cn6 Sch3erbel C* Camit? 6* Crahmer A* Hallahan A* 7Mhnert M* %ottmann P* 8ebe; S* Schallschmidt <* 6rends D* Schumacher 2* Cleuser B* Haltenhof <* He"d 2* %ancheva S* Broman KW* 1oden M* 7oost H%* 'hadt 6* 6l-Hasani H* Vo&el H* 7onas #* SchNrmann 6 52020: Immunit"-related %<Pase induces lipopha&" to prevent e@cess hepatic lipid accumulation9 J 0epatol ,+-,,1$,.2 doi-10F&Kpn?; Broman KW 52020: 1eproducibilit" report- Identif"in& essential &enes by muta&enesis9 #eScience C 651:- O12 doi-109)2.1F?enodo9+9)9)16 1odri&ue?-%il 78* Wat;ins-'ho3 D/* Ba@ter 88* /lliot %* Harper 8* Wincovitch SM* Wedel 7'* Incao 66* Huebec;er M* Boehm 27* %arver WS* Porter 2D* Broman KW* Platt 2M* Pavan B7 52020: %enetic bac;&round modi4es phenot"pic severit" and lon&evit" in a mouse model of Niemann-Pic; Disease <"pe '19 3is Model Mec! 1+-dmm0(261( doi-10912(2Fdmm90(261( -./4 Celler MP* 1aba&lia M/* Schueler C8* Stapleton DS* %atti DM* Vincent M* Mito; C6* Wan& P* Ishimura <* Simonett SP* /m4n&er 'H* Das 1* Bec; <* Cend?iors;i