OBESITY2012 30th Annual Scientific Meeting San Antonio, Texas | Sept. 20–24 Abstract Book Platinum Plus Sponsorship About The Obesity Society The Obesity Society (www.obesity.org) is the leading professional society dedicated to the study, prevention and treatment of obesity. Since 1982, the society has been committed to encouraging research on the causes, treatment, and prevention of obesity as well as keeping the scientific community and public informed of new advances in the field. Gold About the Meeting Sponsorship Obesity 2012, the 30th Annual Scientific Meeting of The Obesity Society, brings together the most prestigious professionals in the field of obesity, from world-renowned basic and clinical researchers to educators, advocates and practitioners. Through its scientific, educational, mentoring and networking events, Obesity 2012 is dedicated to increasing knowledge, stimulating research, furthering careers, and promoting prevention and better treatment for those affected by obesity. Attendees will take part in scientific and education sessions, oral and poster presentations, and other programs covering the full interdisciplinary regimen of obesity research, education, Silver advocacy and development, including key lectures from the top professionals in each field. Sponsorship » Metabolism and Integrative Physiology » Neuroscience » Intervention and Clinical Studies » Population Health » Clinical and Professional Practice – Policy All Attendees Have Access to Obesity Online! Audio Recordings of Obesity Continuing Education Credits for 2012 Sessions Obesity 2012 » Listen to recordings of and view slides for annual » Attendees may complete session evaluations, claim scientific meeting sessions that you couldn’t credits and print certificates online attend onsite » Attendees may choose from CME, CNE, CPE, ACPE, » Replay meeting highlights all year or CEU credit types » Download audio synchronized-to-PowerPoint slide presentations anytime, anywhere! All of this is included with your Obesity 2012 registration » Access to online sessions will be available starting Simply visit Obesity Online at in mid-November www.softconference.com/obesity » Colleagues who did not attend the Annual Meeting but wish to view content may purchase individual Learn more about Obesity Online by visiting the sessions or the entire set of conference recordings! Education Booth in the Exhibit Hall 01_TOS12_Frontmatter-2 9/4/12 3:16 PM Page i Obesity 2012 Abstracts September 20 – 24, 2012 San Antonio, TX 01_TOS12_Frontmatter-2 9/4/12 3:16 PM Page ii ANNUAL PROGRAM Obesity 2012 Abstract Reviewers COMMITTEE CHAIR Sean Adams, PhD Marie-France Hivert, MD Carey Lumeng, MD, PhD Sandra Albrecht, PhD Frank Hu, MD CO-CHAIR Zane Andrews, PhD Matthew Hulver, PhD Alison E. Field, ScD David Arterburn, MD, MPH Thomas Inge, MD CLINICAL AND PROFESSIONAL PRACTICE Prabhakaran Balagopal, PhD Lisa Jahns, PhD, RD Rita Basu, MD Jill Kanaley, PhD Jamy Ard, MD Cathy Nonas, MS, RD, CDE – Harold Bays, MD Scott Kanoski, PhD Track 5 Chair Nicholas Bello, PhD Peter Katzmarzyk, PhD Lawrence J. Cheskin, MD, FACP Kendra Bence, PhD John Kirwan, PhD Edy Heydinger, APRN, MSN, CPNP Martin Binks, PhD Rohit Kohli, MBBS, MS Carol Motycka, PharmD Sara Bleich, PhD Catherine Kotz, PhD David Sarwer, PhD Dale Bond, PhD Lorraine Lanningham- INTERVENTION AND CLINICAL STUDIES Ingrid Borecki, PhD Foster, MD Jennifer Fisher, PhD – Andrew Bremer, MD, PhD Scott Lear, PhD Track 3 Chair Joshua Brown, PhD Ruth Loos, PhD Kishore Gadde, MD Lora Burke, PhD, MPH Amy Luke, PhD Bret H. Goodpaster, PhD Andrew Butler, PhD Carey Lumeng, MD, PhD Corby Martin, PhD Nancy Butte, PhD Julie Lumeng, MD METABOLISM AND INTEGRATIVE Noel Cameron, PhD Corby Martin, PhD PHYSIOLOGY Sarah Camhi, PhD Megan McCrory, PhD Rosalind Coleman, MD Catherine Champagne, PhD Timothy Moran, PhD Ruth Harris, PhD Jean-Philippe Chaput, PhD Naima Moustaid-Moussa, PhD Mary-Ellen Harper, PhD Lawrence Cheskin, MD Heike Munzberg, PhD Elizabeth Parks, PhD – Rosalind Coleman, MD Barbara Nikolajczyk, PhD Track 1 Chair Anthony Comuzzie, PhD Kari North, PhD Andre Tchernof, PhD Kirsten Davison, PhD Elizabeth Parks, PhD NEUROSCIENCE James DeLany, PhD Mark Pereira, PhD Andrew Butler, PhD – Ellen Demerath, PhD Karen Peterson, ScD Track 2 Chair Gerald Denis, PhD Suzanne Phelan, MD Matthew R. Hayes, PhD Nikhil Dhurandhar, PhD Angelo Pietrobelli, MD Timothy H. Moran, PhD Joseph Donnelly, EdD Paul Poirier, MD Gary Schwartz, PhD Dariush Elahi, PhD Barry Popkin, PhD POPULATION HEALTH AND POLICY Jose Fernandez, PhD Thomas Robinson, MD, MPH Scott Lear, PhD – Track 4 Chair Alison Field, ScD Cheryl Rock, PhD Ingrid Borecki, PhD Eric Finkelstein, PhD Stephanie Rose, MD, MPH Thomas N. Robinson, MD, MPH Jennifer Fisher, PhD Domenica Rubino, MD Meghan M. Slining, PhD, MPH Caroline Fox, MD, MPH Donna Ryan, MD STAFF LIAISON Simone French, PhD Gary Schwartz, PhD Lauren Maza, Dir., Scientific Mtgs. Kishore Gadde, MD Meghan Slining, PhD, MPH & Education Dympna Gallagher, EdD Jacqueline Stephens, PhD COUNCIL LIAISON Bethany Barone Gibbs, PhD Gladys Strain, PhD Patrick M. O’Neil, PhD, President Matthew Gillman, MD Guang Sun, MD, PhD Bret Goodpaster, PhD Kellie Tamashiro, PhD Paul Gordon, PhD, MPH Andre Tchernof, PhD Penny Gordon-Larsen, PhD Kimberly Truesdale, PhD Frank Greenway, MD Youfa Wang, MD, PhD Mary-Ellen Harper, PhD Dianne Ward, EdD Ruth Harris, PhD Christina Wee, MD, MPH Matthew Hayes, PhD Bruce Wolfe, MD Erin Hennessy, PhD Tongjian You, PhD Steven Heymsfield, MD Lori Zeltser, PhD James Hill, PhD ii www.obesity.org/obesity2012 01_TOS12_Frontmatter-2 9/4/12 3:16 PM Page iii Obesity Society 2012 Council PRESIDENT SECRETARY/TREASURER BASIC/EXPERIMENTAL AT-LARGE CANADA Patrick M. O’Neil, PhD Dale A. Schoeller, PhD Naima Moustaid-Moussa, Diane T. Finegood, PhD Medical University of South Department of Nutritional Sciences, PhD Michael Smith Foundation for Carolina University of Wisconsin-Madison University of Tennessee Health Research Charleston SC Madison, WI Knoxville, TN Vancouver, BC, Canada IMMEDIATE COUNCILORS CLINICAL CARE AT-LARGE MEXICO PAST-PRESIDENT IASO REGIONAL VICE Denise E. Wilfley, PhD Margarita Teran-Garcia, Jennifer C. Lovejoy, PhD PRESIDENT Washington University of St. Louis MD, PhD Alere, Inc. St. Louis, MO University of Illinois Seattle, WA Richard L. Atkinson, MD Urbana-Champaign Virginia Commonwealth University ADVOCACY/PUBLIC AFFAIRS Champaign, IL PRESIDENT-ELECT Richmond, VA Rebecca M. Puhl, PhD EXECUTIVE DIRECTOR Harvey J. Grill, PhD POPULATION/EPIDEMIOLOGY Rudd Center for Food Policy and University of Pennsylvania Obesity, Yale University Francesca M. Dea, Pennsylvania, PA Nancy F. Butte, PhD New Haven, CT CAE, MBA Baylor College of Medicine VICE-PRESIDENT AT-LARGE The Obesity Society Houston, TX Silver Spring, MD Steven R. Smith, MD CLINICAL/TRANSLATIONAL Alison E. Field, ScD Translational Research Institute for Children’s Hospital Metabolism and Diabetes (TRI) David Heber, MD, PhD, Boston, MA Winter Park, FL CNS, FACP, FACN AT-LARGE University of California Los Angeles, CA Melissa N. Laska, PhD, RD University of Minnesota Minneapolis, MN Obesity Society Staff The Obesity Society 8757 Georgia Avenue, Suite 1320 Silver Spring, MD 20910 Tel: 301-563-6526 Fax: 301-563-6595 EXECUTIVE DIRECTOR MEMBERSHIP ASSISTANT EDITORIAL ASSISTANT Francesca M. Dea, Kelly Evans Lorrie Brescia CAE, MBA SENIOR DIRECTOR, DIRECTOR, SCIENTIFIC GOVERNANCE AND PUBLICATIONS, MARKETING MEETINGS AND EDUCATION EXECUTIVE ASSISTANT & COMMUNICATIONS Lauren Maza, CAE, MBA Sadie Campbell Hedy Ross, MBA MANAGER OF EDUCATION SENIOR DIRECTOR, FINANCE MANAGER OF Maya Cunningham AND ADMINISTRATION COMMUNICATIONS Kathie Cleary John-Aaron Blanchette FINANCE ASSISTANT EDITORIAL ASSISTANT Lorna Pool Deborah Rice Obesity 2012, The 30th Annual Scientific Meeting of The Obesity Society iii 01_TOS12_Frontmatter-2 9/4/12 3:16 PM Page iv Learning Objectives, Accreditation and Continuing Education Learning Objectives Accreditation and Continuing At the conclusion of this meeting, Education Credit attendees will be able to: » Analyze results from recent basic Physicians Pharmacists research studies in cell and The Obesity Society is accredited by Accreditation molecular biology (signal transduc- the Accreditation Council for Continu- Statement tion, substrate/fuel metabolism, ing Medical Education (ACCME) to The Minnesota Pharmacists Associa- provide continuing medical education tion is accredited by the Accredita- transcriptional regulation) and for physicians. tion Council for Pharmacy Education assess their potential clinical (ACPE) as a provider of continuing implications on the causes and The Obesity Society designates this education. Successful completion of treatment of obesity and its related live educational activity for a maximum this program qualifies for a maximum comorbidities. of 21.50 AMA PRA Category 1 Cred- of 21.50 contact hours. its™. Physicians should only claim » Analyze results from recent basic credit commensurate with the extent of research studies in integrative their participation in the activity. Nurses biology (CNS and gut regulation Aspen CME Services is an approved of energy balance, animal and International CME provider of continuing nursing educa- human physiology) and assess their tion by the Wisconsin Nurses Associa- International Physicians are potential clinical implications on the tion, an accredited approver by the formally eligible for AMA PRA American Nurses Credentialing causes and treatment of obesity Category 1 Credit™. and its related comorbidities.