Collagen Peptides – Innovative technologies for innovative ideas! What are Collagen Peptides? Collagen Peptides are functional digested and fully utilized by the body. Collagen Peptides are also non-allergenic short chains of amino acids produced and suitable for clean label products. by the simple hydrolysis of collagen GELITA offers a versatile portfolio of different protein. Depending on the applied Collagen Peptides, including specific Bioactive Collagen Peptides®, which are optimized for enzymatic process, Collagen Peptides targeted health benefits e. g. FORTIBONE® for will deliver excellent solutions for Bone Health or VERISOL® for Beauty from within and TENDOFORTE® for Ligaments & Tendons. food applications and specific health Collagen Peptides are a pure source of protein benefits. that originates from collagen, a mammalian extracellular matrix protein. Collagen Peptides are characterized by their Due to their unique functionality GELITA® particular molecular weight distribution profile Collagen Peptides are ideal protein solutions to and high bioavailability. They are pure sources of combine with other food ingredients for a variety collagen protein amino acids that are rapidly of food and health & nutrition applications. Pretreatment of the Raw Material Enzymatic Process Purification (Hydrolysis of collagen (Filtration, Demineralization) into specific peptides) Enzyme Blend pH Temper- Time ature Separation Thermal/ Specific and Chemical controlled Hydrolysis enzymatic hydrolysis Native collagen Bioactive in raw material Collagen Peptides® [2] GELITA® Collagen Peptide Portfolio Beauty from Within Advantages in food applications Joint Health Human • Excellent solubility Pet • Heat-stability • Stable against food acids Bone Health • Brilliant clarity Ligaments & Tendons • No precipitation or flocculation Body Toning in liquid applications • Low viscosity Endurance • Neutral in taste and odor Protein Enrichment GELITA® Collagen Peptides are tailor made proteins fashioned by a safe and certified production process (ISO 9001, ISO 14001, ISO 50001 & FSSC 22000). GELITA’s portfolio also includes PEPTIPLUS®, a family The key of this technology is the enzymatic step of Collagen Peptide products, specialized for protein cutting the collagen into specific peptides. enrichment and technical food applications. Concentration Sterilization Spray Dryer UHT Flow of raw materials or products Packing, Storage Joints Finished product Automatic packing warehousing Specific and Bones Thermal/ Chemical controlled Hydrolysis enzymatic Muscles hydrolysis Skin Ligaments Native collagen Bioactive in raw material Collagen Peptides® [3] Why to use GELITA® Collagen Peptides? Collagen is a major component of the human Bioactive Collagen Peptides® body – making up about 30 % of our total body stimulate collagen metabolism protein. Collagen is crucial for mobile joints, stable bones, healthy muscles, strong ligaments GELITA Bioactive Collagen Peptides® (BCPs) and tendons, smooth skin, glossy hair and healthy include a range of specific peptides optimized finger nails. It is one of the primary structural for targeted health benefits. They directly stimu- proteins of connective tissues and also abundant late the metabolism of target connective tissue in blood vessels, intervertebral discs, the blood- cells involved in collagen biosynthesis. Further- brain barrier, the cornea, dentin and the intestinal more, as all GELITA® Collagen Peptides they provide wall – a vital component of our whole body. a number of physiological and technical benefits making them the perfect supplement to realize innovative product ideas in the fields of health, beauty and sports nutrition. Bioactive Collagen Peptides® Skin Health Fibroblasts VERISOL® Joint Health Chondrocytes FORTIGEL® Bone Health Osteoblasts/ FORTIBONE® Osteoclasts Ligaments/ Ligamentocytes/ TENDOFORTE® Tendons Tenocytes Osteoporosis Body Toning Muscle cells BODYBALANCE® resistance exercise Endurance Muscle cells PeptENDURE® endurance performance Normal bone matrix [4] Why to use GELITA ® Collagen Peptides? Which benefits provide GELITA ® Collagen Peptides? • Pure Food Protein (up to 98 % protein in dry matter) GELITA ® Collagen Peptides • Safe according to an excellent sensorial profile have Reg. (EC) No 853/2004 • Non Allergenic (Mammalian Source) mouth color • Clean label feeling • Non GMO Products turbidity • FDA GRAS status after (Docket Number 77N-0232) taste • KOSHER/HALAL 0 smell (bovine origin) salty sour GELITA ® Collagen Peptides have a consistent bitter 6 typical amino acid and nutritional profile and sweet are free from fat, sugar, cholesterol, purines and PEPTIPLUS® Soy protein additives. They offer clean-label opportunities. Whey protein Sensorial evaluation of PEPTIPLUS on a scale of: 0 = not noticable to® ,6 Whey = strong and Soy The powder and liquid form of Collagen Peptides show an excellent sensorial profile suitable for sophisticated applications like beverages or powder products. Technical Product Data PEPTIPLUS® XB aggl. Comprising PEPTIPLUS® XB aggl., PEPTIPLUS® XB (SA) aggl., PEPTIPLUS® XB (US) aggl., PEPTIPLUS® XB (NL) aggl., Product description: Application and Service: PEPTIPLUS® XB aggl. are highly purified PEPTIPLUS® XB aggl. is suitable for protein enrichment in food such Collagen Peptides from bovine skin. The as bars, gums and beverages. average molecular weight is between 2,500 – 4,000 g/mol. Shelf life: Under dry and odorless conditions PEPTIPLUS® XB aggl. can be Characteristics: stored in the original unopened packaging at ambient temperatures Nutritional profile Light colored, agglomerated powder with a (< 30°C) for 5 years without loss of quality. bulk density between 270 - 400 g/L. Nutrient Specifically neutral in taste and odor and Packages: Energy value (per 100g) excellently soluble in cold and warm water. Multi-ply paper bags with PE-liner containing 15 kg net. (average) PEPTIPLUS® XB aggl. is pure collagen : Fat 2 protein with an extremely low mineral of which Typical value content and is free of fat, cholesterol, Microbiological limits: carbohydrates, and dietary fibers. Chemical/Physical Data: -saturates 1,530 kJ (360 kcal) -trans fat 2 Parameter Parameter Test Method Value Total aerob. micro. count Cholesterol 0 g Protein content Kjeldahl (N x 5.55) 91 – 96 % 5 Carbohydrates Total yeast/mould count Amino acid composition Protein content based on GELITA method ≥ 97 % of which Sulfite re. anaer. spores dry substance 2 0 g Test Method Escherichia coli Amino acid Weight (%) Dry substance (105 °C, 16 h) GME3 91 – 96 % -sugars 0 g Ph. Eur./USP 2 Salmonella 2 Protein Ash (550°C) USP/GME 0.9 % 0 g Ph. Eur./USP Alanine 8.6 ≤ 6 Salt Arginine 7.3 pH (20 %, RT) Potentiometer 5.0 – 6.4 0 g AFNOR NF V59-106 Value Sodium < 1000 cfu/g Aspartic acid 5.8 Viscosity (20 %, 25°C) GELITA method 3.00 – 5.00 mPa s Ph. Eur./USP mod. Allergen information Vitamin D 0 g ISO 6579 < 100 cfu/g Glutamic acid 10.2 ≥ 90% below 425 µm (40 mesh) 90.0 g Particle distribution Sieve Test / DLS Calcium < 10 cfu/g Glycine 22.2 15% below 75 µm Allergens (REG (EU) No 1169/2011) / USDA ≤ 0.5 g negative / 10 g (200Iron mesh) Not a significant source Cereals containing gluten, namely wheat (such as spelt and Histidine 1.0 Khorasan wheat), rye, barley, oats, spelt, kamut or their negative / 25 g Peroxides Ph. Eur./GME ≤ 10Potassium mg/kg Not a significant source0.2 g Isoleucine 1.4 hybridized strains, and products thereof 2 Sulphur dioxide Ph. Eur./GME ≤ 10 mg/kg Not a significant source Crustaceans and products thereof Leucine 2.7 6The protein is calculated from the nitrogen content by Arsenic2 ICP-OPS ≤using 1.0 mg/kgthe factor 5.55 as describedNot a insignificant Jones, D.B. source (1941) Eggs and products thereof Lysine 3.6 US. Dept. Agric. Circ. 183 (revised). Cadmium2 ICP-OPS ≤ 0.1 mg/kg Fish and products thereof Hydroxylysine 1.6 Chromium2 ICP-OPS ≤ 10.0 mg/kg Peanuts and products thereof Methionine 0.9 contains Copper2 ICP-OPS Regulatory≤ 30.0 mg/kg Issues: Soybeans and products thereof Phenylalanine 2.1 2 Milk and products thereof (including lactose) No Mercury AAS PEPTIPLUS≤ 0.1 mg/kg Proline 12.7 Nuts, namely almonds, hazelnuts, walnuts, cashews, pecan 2 extremely low mineral content and is free of fat, Lead ICP-OPS ≤ 0.5 mg/kg® Hydroxyproline 11.9 cholesterol, carbohydrates, XB aggl. is puredietary collagen fibers proteinand GMO. with an nuts, Brazil nuts, pistachio nuts, macadamia or Queensland No 2 nuts, and products thereof Zinc ICP-OPS The product≤ 30.0 is mg/kg in accordance with FDA regulations, No Serine 3.2 HACCP, ISO9001:2015 and FSSC22000:2010. Celery and products thereof No Threonine 1.8 Classified as GRAS (Generally Regarded As Safe). Mustard and products thereof Furthermore, the product is in compliance with 2Reduced frequency testing in accordance to an internal quality program. No Tyrosine 0.8 regulation (EC) No. 852/2004 on the hygiene of Sesame seeds and products thereof The values given are based on average GELITA monitoring foodstuffsdata at the and time with of regulation printing. (EC) No. 853/2004, laying No 2.4 Sulphur dioxide and sulphites (E220 - E228) at concentrations of Valine These values are for information only. down specific hygiene rules for food of animal origin. 3 > 10 No GME, Gelatine Manufactures of Europe According to regulation (EC) No. 1829/2003 and mg/kg or > Lupin and products thereof 4determined due to national regulations and requirements regulation– not standard (EC) No. 1830/2003 the product has not to 10 5Average score for typical collagen