GLOBAL FILTER OPTIMIZING THE FERMENTATION PROCESS THROUGH FILTRATION TABLE OF CONTENTS WHAT IS FERMENTATION...................................................01 FERMENTATION PROCESS.................................................02 ROLE OF FILTRATION...........................................................03 PLACEMENT WITHIN THE PROCESS..............................04 01 WHAT IS FERMENTATION WHAT IS FERMENTATION FERMENTATION DEFINED: Fermentation: Industrial Fermenation: The metabolic process (anaerobic The use of fermentation on a very large decomposition) of carbohydrates (sugars scale to produce products ranging from & starches) utilizing bacteria, yeast, or biofuels, citric & acetic acid, vinegar, and other microorganisms to produce acids, food-grade enzymes. gases, or alcohols. PRODUCTS MANUFACTURED BY INDUSTRIAL FERMENTATION: • Alcohols • Industrial Enzymes & Proteins • Polyols • Vitamins • Lactic Acid • Biofuels (ethanol) • Acetic Acid • Acetone • Polysaccharides • Amino acids • Biodegradable Plastics (lysine, MSG, serine, etc) 02 FERMENTATION PROCESS GENERAL FERMENTATION PROCESS In most industrial fermentation processes, the microorganisms are submerged in a liquid medium (usually called a broth). The broth provides nutrients to the microorganism to feed growth. In order to ensure against contamination, the broth, feed air, and all equipment is sterilized. Feed air needs to be free of particulates, outside organisms, and moisture. Ph and temperature are constantly monitored and adjusted. 03 ROLE OF FILTRATION IN THE FERMENTATION PROCESS ROLE OF FILTRAION IN THE FERMENTATION PROCESS The metabolic process (anaerobic Global Filter offers nearly every decomposition) of carbohydrates (sugars & variation of technology used starches) utilizing bacteria, yeast, or other throughout the fermentation microorganisms to produce acids, gases, or processes. alcohols. FILTRATION APPLICATIONS Cooling Water Water removal (if necessary): Bulk solids: Nominally rated pleated polypropylene, string- Air/liquid coalescer wound, or meltblown cartridges (1-5 microns). Changed on DP Final Filtration: Broth (maceration) Prefiltration: Sterilizing grade hydrophobic membrane rated at 0.2 micron Absolute rated pleated polypropylene (PP) or microglass (FG) (BRPTFE or PPTFE). Many users are satisfied with an aerosol depth cartridges (0.45-1.0 microns). Changed on DP. validated cartridge rather than a liquid validated cartridge (significantly less costly). Changed based on PM (usually Final filtration: quarterly or bi-annually). Bacteria-retentive membrane cartridges rated at 0.2 micron (BRPES or PPES). Cartridges are typically changed based on Tank vent pre-set number of batches processed (steam sterilized & integrity Final Filtration: tested between batches). Sterilizing grade hydrophobic membrane rated at 0.2 micron (BRPTFE or PPTFE). Changed based on PM (usually quarterly or Feed Air Prefiltration: bi-annually). Absolute rated polypropylene (PP) or microglass (FG) pleated depth cartridges (0.45-1.0 microns). Cartridges require endcap support ring for steam sterilization. Cartridges are typically changed based on DP or PM. 04 PLACEMENT WITHIN THE FILTRATION PROCESS FILTER PLACEMENT WITHIN THE FERMENTATION PROCESS H2O Gas Duct This schematic should be viewed as a general example of where filtration systems could be located within a fermentation process. These processes will vary Global Global PTFE or PP or MB PSH Elements between companies and facilities. As such, each appli- Elements FILTER cation should be reviewed and considered individually FILTER in order to choose the correct system technology. 2 4 Air 1 FILTER Global Nutrient Fermentation Storage PTFE or PSH Tank Tank Elements Tank 3 FILTER Global PTFE or PSH Elements DE Filter Microfiltration Ultrafiltration DE Trap Prefilters Prefilters Prefilters Filter FILTER FILTER FILTER FILTER FILTER FILTER FILTER 11 10 7 6 5 9 8 Global Global Global Global Global Global Global PES PP or FG PP or FG PES PP or FG PES PP or FG Elements Elements Elements Elements Elements Elements Elements Drums for final product Filter Solutions for Stages of the Fermentation Process Location Global Filter Solutions Filter Purpose Filter Benefit Removal of particulated such as PTFE Hydrophobic Membrane Maintains aeration efficiency for bacterial 1. PS Hydrophobic Membrane sediment, suspended solids, pipe General Grade • Polysulfone - PSH Series growth and production Inlet Air • GGPTFE, BRPTFE, PPTFE Series scale, etc. from process water Removal of particulate and 2. Polypropylene Meltblown Pleated Polypropylene Maintains water quality as an ingredient Inlet H20 • GWTB, GCTB, GATB Series • PP, PPE Series bateria from process air Allows for bacteria free air passage during 3. - 4. PTFE Hydrophobic Membrane filling and evacutaiton, protecting the PS Hydrophobic Membrane Fermentation tank vent filtration Fermentation General Grade • Polysulfone - PSH Series fermentation tank and its contents from Tank • GGPTFE, BRPTFE, PPTFE Series contamination Installed downstream of the Maintains high quality of the process and Diatomaceous Earth (DE) filter to 5. Pleated Microglass Pleated Polypropylene minimized sediment and poor quality DE Trap Filter • FG, FGE Series • PP, PPE Series prevent DE bleed-through fines perception of the final product from entering product Pleated Microglass Pleated Polyethersulfone 6. - 11. • FG, FGE Series • GWPES, WCPES, GGPES, GFPES, Removal of coarse and fine Pre-filtration of finished product before Pre and Post GBPES, BRPES, PPES Series Filtration to Micro particulate micro and ultrafiltration and Ultrafiltration Pleated Polypropylene • PP, PPE Series LET GLOBAL FILTER OPTIMIZE YOUR FERMENTATION PROCESS ADDRESS CONTACT GLOBAL FILTER Phone 7201 Mt. Vernon Rd. SE Phone: + 1 877.603.1003 Cedar Rapids, Iowa 52403 Fax: + 1 319 743 0220 United States of America Online Email: [email protected] Website: www.globalfilter.com.