SAFETY DATA SHEET Creation Date 09-Apr-2018 Revision Date 27-Dec-2020 Revision Number 3 SECTION 1: IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING 1.1. Product identifier Product Description: (1,3-Dioxolan-2-ylmethyl)zinc bromide, 0.5M in THF Cat No. : H58702 Molecular Formula C4 H7 BrO2 Zn Unique Formula Identifier (UFI) WJHG-P6MS-AX0X-YM3S 1.2. Relevant identified uses of the substance or mixture and uses advised against Recommended Use Laboratory chemicals. Uses advised against No Information available 1.3. Details of the supplier of the safety data sheet Company Thermo Fisher (Kandel) GmbH . Erlenbachweg 2 76870 Kandel Germany Tel: +49 (0) 721 84007 280 Fax: +49 (0) 721 84007 300 E-mail address [email protected] www.alfa.com Product safety Tel + +049 (0) 7275 988687-0 1.4. Emergency telephone number Carechem 24: +44 (0) 1235 239 670 (Multi-language emergency number) Poison Information Center Mainz www.giftinfo.uni-mainz.de Telephone: +49(0)6131/19240 Exclusively for customers in Austria: Poison Information Center (VIZ) Emergency call 0-24 clock: +43 1 406 43 43 Office hours: Monday to Friday, 8am to 4pm, tel: +43 1 406 68 98 Poison Centre - Emergency Ireland : National Poisons Information Centre (NPIC) - information services 01 809 2166 (8am-10pm, 7 days a week) Malta : +356 2395 2000 Cyprus : +357 2240 5611 SECTION 2: HAZARDS IDENTIFICATION 2.1. Classification of the substance or mixture CLP Classification - Regulation (EC) No 1272/2008 ______________________________________________________________________________________________ ALFAAH58702 Page 1 / 13 SAFETY DATA SHEET (1,3-Dioxolan-2-ylmethyl)zinc bromide, 0.5M in THF Revision Date 27-Dec-2020 ______________________________________________________________________________________________ Physical hazards Flammable liquids Category 2 (H225) Health hazards Acute oral toxicity Category 4 (H302) Skin Corrosion/Irritation Category 2 (H315) Serious Eye Damage/Eye Irritation Category 2 (H319) Carcinogenicity Category 2 (H351) Specific target organ toxicity - (single exposure) Category 3 (H335) (H336) Environmental hazards Based on available data, the classification criteria are not met Full text of Hazard Statements: see section 16 2.2. Label elements Signal Word Danger Hazard Statements H225 - Highly flammable liquid and vapor H302 - Harmful if swallowed H315 - Causes skin irritation H319 - Causes serious eye irritation H335 - May cause respiratory irritation H336 - May cause drowsiness or dizziness H351 - Suspected of causing cancer EUH019 - May form explosive peroxides Precautionary Statements P210 - Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking P303 + P361 + P353 - IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower P301 + P330 + P331 - IF SWALLOWED: rinse mouth. Do NOT induce vomiting P312 - Call a POISON CENTER or doctor/physician if you feel unwell P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing P337 + P313 - If eye irritation persists: Get medical advice/attention P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing P280 - Wear protective gloves/protective clothing/eye protection/face protection P332 + P313 - If skin irritation occurs: Get medical advice/attention 2.3. Other hazards Toxic to terrestrial vertebrates ______________________________________________________________________________________________ ALFAAH58702 Page 2 / 13 SAFETY DATA SHEET (1,3-Dioxolan-2-ylmethyl)zinc bromide, 0.5M in THF Revision Date 27-Dec-2020 ______________________________________________________________________________________________ SECTION 3: COMPOSITION/INFORMATION ON INGREDIENTS 3.2. Mixtures Component CAS-No EC-No. Weight % CLP Classification - Regulation (EC) No 1272/2008 Tetrahydrofuran 109-99-9 EEC No. 203-726-8 88.4 Flam. Liq. 2 (H225) Acute Tox. 4 (H302) Eye Irrit. 2 (H319) STOT SE 3 (H335) STOT SE 3 (H336) Carc. 2 (H351) (EUH019) (1,3-Dioxolan-2-ylmethyl)zinc bromide 1135389-59-1 11.6 Flam. Liq. 2 (H225) Skin Irrit. 2 (H315) Eye Irrit. 2 (H319) STOT SE 3 (H335) Acute Tox. 4 (H312) Acute Tox. 4 (H332) Acute Tox. 4 (H302) Component Concentration limits M-Factor Component notes Tetrahydrofuran STOT SE 3 :: C>=25% - - Eye Irrit. 2 :: C>=25% Acute Tox. 4 :: C>82.5% Full text of Hazard Statements: see section 16 SECTION 4: FIRST AID MEASURES 4.1. Description of first aid measures General Advice If symptoms persist, call a physician. Eye Contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Get medical attention. Skin Contact Wash off immediately with plenty of water for at least 15 minutes. If skin irritation persists, call a physician. Ingestion Clean mouth with water and drink afterwards plenty of water. Inhalation Remove to fresh air. If not breathing, give artificial respiration. Get medical attention if symptoms occur. Self-Protection of the First Aider Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and prevent spread of contamination. 4.2. Most important symptoms and effects, both acute and delayed None reasonably foreseeable. Inhalation of high vapor concentrations may cause symptoms like headache, dizziness, tiredness, nausea and vomiting 4.3. Indication of any immediate medical attention and special treatment needed Notes to Physician Treat symptomatically. Symptoms may be delayed. ______________________________________________________________________________________________ ALFAAH58702 Page 3 / 13 SAFETY DATA SHEET (1,3-Dioxolan-2-ylmethyl)zinc bromide, 0.5M in THF Revision Date 27-Dec-2020 ______________________________________________________________________________________________ SECTION 5: FIREFIGHTING MEASURES 5.1. Extinguishing media Suitable Extinguishing Media Dry sand. Carbon dioxide (CO 2). Powder. Do not use water or foam. Water mist may be used to cool closed containers. Extinguishing media which must not be used for safety reasons No information available. 5.2. Special hazards arising from the substance or mixture Flammable. Containers may explode when heated. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Hazardous Combustion Products Carbon monoxide (CO), Carbon dioxide (CO2), Hydrogen bromide, Metal oxides. 5.3. Advice for firefighters As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear. SECTION 6: ACCIDENTAL RELEASE MEASURES 6.1. Personal precautions, protective equipment and emergency procedures Ensure adequate ventilation. Use personal protective equipment as required. Remove all sources of ignition. Take precautionary measures against static discharges. 6.2. Environmental precautions Should not be released into the environment. Do not allow material to contaminate ground water system. Do not flush into surface water or sanitary sewer system. 6.3. Methods and material for containment and cleaning up Soak up with inert absorbent material. Keep in suitable, closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. 6.4. Reference to other sections Refer to protective measures listed in Sections 8 and 13. SECTION 7: HANDLING AND STORAGE 7.1. Precautions for safe handling Wear personal protective equipment/face protection. Ensure adequate ventilation. Do not get in eyes, on skin, or on clothing. Avoid ingestion and inhalation. If peroxide formation is suspected, do not open or move container. Keep away from open flames, hot surfaces and sources of ignition. Use only non-sparking tools. To avoid ignition of vapors by static electricity discharge, all metal parts of the equipment must be grounded. Take precautionary measures against static discharges. Hygiene Measures Handle in accordance with good industrial hygiene and safety practice. Keep away from food, drink and animal feeding stuffs. Do ______________________________________________________________________________________________ ALFAAH58702 Page 4 / 13 SAFETY DATA SHEET (1,3-Dioxolan-2-ylmethyl)zinc bromide, 0.5M in THF Revision Date 27-Dec-2020 ______________________________________________________________________________________________ not eat, drink or smoke when using this product. Remove and wash contaminated clothing and gloves, including the inside, before re-use. Wash hands before breaks and after work. 7.2. Conditions for safe storage, including any incompatibilities Keep refrigerated. Keep container tightly closed in a dry and well-ventilated place. Containers should be dated when opened and tested periodically for the presence of peroxides. Should crystals form in a peroxidizable liquid, peroxidation may have occurred and the product should be considered extremely dangerous. In this instance, the container should only be opened remotely by professionals. Keep away from heat, sparks and flame. Technical Rules for Hazardous Substances (TRGS) 510 Storage Class (LGK) Storage Class/LGK 3 (Germany) 7.3. Specific end use(s) Use in laboratories SECTION 8: EXPOSURE CONTROLS/PERSONAL PROTECTION 8.1. Control parameters Exposure limits UK - EH40/2005 Work Exposure Limits, Third edition. Published 2018. IRE - 2010 Code of Practice for the Safety, Health and Welfare at Work (Chemical Agents) Regulations 2001. Published by the Health