ACCP Toolkit The 2016 ACCP Pharmacotherapy Didactic Curriculum Toolkit 2016 Educational Afairs Committee, American College of Clinical Pharmacy Terry L. Schwinghammer (Chair), Andrew J. Crannage (Vice Chair), Eric G. Boyce, Bridget Bradley, Alyssa Christensen, Henry M. Dunnenberger, Michelle Fravel, Holly Gurgle, Drayton A. Hammond, Jennifer Kwon, Douglas Slain, and Kurt A. Wargo. Approved by the American College of Clinical Pharmacy Board of Regents on July 18, 2016. The purpose of the 2009 and 2016 ACCP Pharmacother- ORGAN SYSTEMS AND DISEASE STATE TOPICS apy Didactic Curriculum Toolkits is to provide guid- ance to schools and colleges of pharmacy in developing, Cardiovascular Disorders maintaining, and modifying their curricula.1,2 The 2016 1 Acute coronary syndromes (STEMI, NSTEMI, unstable ACCP Educational Affairs Committee reviewed recent angina) medical literature and other documents to identify dis- 1 Atherosclerotic cardiovascular disease, primary ease states that are responsive to drug therapy. Disease prevention frequency, socioeconomic burden to society, and impact 1 Atherosclerotic cardiovascular disease, secondary of pharmacist involvement in medication therapy were prevention considered in determining which topics to include in the updated pharmacotherapy toolkit. This updated toolkit 1 Arrhythmias, atrial (e.g., atrial fbrillation) is intended to provide valuable guidance to schools and 1 Basic life support (BLS) colleges of pharmacy as they develop, maintain, and 1 Dyslipidemia modify their curricula to keep pace with major scientific 1 Heart failure, chronic advances and practice changes. 1 Hypertension In the 2016 toolkit, diseases and content topics are 1 Ischemic heart disease, stable organized by organ system, when feasible, and grouped 1 Venous thromboembolism into tiers defined by practice competency. Within each organ system, topics are listed by tier level and then al- 2 Advanced cardiac life support (ACLS) phabetically within tiers. The tier levels assigned by the 2 Arrhythmias, ventricular 2016 Educational Affairs Committee differ from those 2 Drug-induced cardiac disease of the 2009 toolkit. Tier assignments are intended for use only as a guide within the context of individual col- 2 Heart failure, acute decompensated lege or school priorities. 2 Hypertensive crises 2 Peripheral arterial disease Competency-Based Tier Defnitions: 2 Pulmonary arterial hypertension 2 Stroke (ischemic, hemorrhagic, and transient ischemic 1. Students receive education and training on this attack) topic to prepare them to provide collaborative, pa- tient-centered care on graduation and licensure. 2 Valvular heart diseases 3 Aneurysm 2. Students receive education and training on this topic, but additional knowledge or skills may be re- 3 Aortic dissection quired after graduation (e.g., residency training) to 3 Cardiomyopathies prepare them to provide collaborative, direct patient 3 Pericarditis care. Dermatologic Disorders 3. Students and residents may not receive education 1 Acne vulgaris and training on this topic; rather, they will be ex- 1 Burn injuries, minor (e.g., sunburn, self-treated burns) pected to obtain the required knowledge and skills 1 Dermatitis (e.g., atopic, contact, diaper) on their own to provide collaborative, direct patient care if required in their practice. 2 Dermatologic Disorders (continued) Gastrointestinal Disorders (continued) 1 Drug-induced dermatologic disorders (e.g., drug reaction 2 Peptic ulcer disease (including stress-related mucosal with eosinophilia and systemic symptoms [DRESS], injury, gastrointestinal bleeding) Stevens-Johnson syndrome, toxic epidermal necrolysis) 2 Pancreatitis (acute, chronic, and drug-induced) 1 Wounds, minor (e.g., lacerations, punctures, bites, 3 Celiac disease incisions, abrasions, avulsions) 3 Liver diseases, metabolic (e.g., hemochromatosis, Wilson 2 Alopecia disease) 2 Photoaging (e.g., actinic keratosis, solar lentigines) Gynecologic and Obstetrical Disorders 2 Psoriasis 1 Contraception 2 Wounds, major (e.g., pressure ulcers) 1 Lactation (e.g., drugs and breastfeeding) 3 Burn injuries, major 1 Menopausal symptoms (e.g., hot fashes, vaginal dryness, Ear, Nose, and Troat Disorders vulvovaginal atrophy) 1 Allergic rhinitis 1 Pregnancy (e.g., pregnancy testing, nutrition & 1 Cerumen impaction supplementation, drug dosing, teratogenicity, nausea/ vomiting) 1 Cough 2 Diabetes mellitus, gestational 1 Otitis externa (swimmer’s ear) 2 Endometriosis and uterine fbroids 1 Rhinorrhea 2 Female sexual dysfunction 1 Sore throat 2 Infertility 3 Ménière disease 2 Labor and delivery (e.g., labor induction, preterm labor) Endocrine Disorders 2 Menstrual cycle disorders (e.g., dysmenorrhea, 1 Diabetes, type 1 menorrhagia) 1 Diabetes, type 2 2 Pregnancy-induced hypertension, preeclampsia, 1 Hypothyroidism eclampsia 2 Adrenal gland disorders (e.g., adrenal insufciency, 3 Polycystic ovary syndrome hypercortisolism) 3 Pregnancy termination 2 Drug-induced endocrine disorders Hematologic Disorders 2 Hyperglycemic crises (diabetic ketoacidosis [DKA], 1 Anemias (e.g., iron defciency, vitamin B12 defciency, hyperosmolar hyperglycemic state [HHS]) folic acid defciency, chronic disease/infammation) 2 Hyperthyroidism 1 Drug-induced hematologic disorders 2 Male hypogonadism 2 Aplastic anemia 3 Pituitary gland disorders (e.g., growth hormone 2 Coagulation disorders (e.g., hemophilia, von Willebrand defciency, acromegaly, hyperprolactinemia) disease, antiphospholipid syndrome, clotting factor 3 Transgender health defciencies) Gastrointestinal Disorders 2 Sickle cell disease 1 Constipation 3 Disseminated intravascular coagulation 1 Diarrhea (including traveler’s diarrhea) 3 Platelet disorders (e.g., idiopathic thrombocytopenic 1 Drug-induced hepatic disorders purpura, thrombotic thrombocytopenic purpura) 1 Gastroesophageal refux disease 3 Porphyrias 1 Nausea & vomiting, simple (e.g., acute viral Immunologic Disorders gastroenteritis, overindulgence, motion sickness) 1 Allergies/drug hypersensitivities (e.g., anaphylaxis, 2 Cirrhosis, end-stage liver disease, and complications desensitization) (e.g., portal hypertension, ascites, varices, hepatic 2 Solid organ transplantation (e.g., heart, liver, lung, encephalopathy, hepatorenal syndrome) kidney; including immunosuppressive therapy) 2 Infammatory bowel disease (Crohn disease, ulcerative 2 Systemic lupus erythematosus colitis) 3 Immunodefciency 2 Irritable bowel syndrome Infectious Diseases 2 Nausea & vomiting, complex (e.g., postoperative, 1 Antimicrobial regimen selection chemotherapy-induced) 1 Clostridium difcile infection 2 Nonalcoholic steatohepatitis 3 Infectious Diseases (continued) Infectious Diseases (continued) 1 Fungal infections, superfcial (e.g., vulvovaginal and 3 Bacterial infections, miscellaneous (e.g., nocardiosis, esophageal candidiasis, dermatophytoses) actinomycosis, Tropheryma whipplei [Whipple disease]) 1 Immunization (including vaccines, toxoids, and other 3 Mycobacterial infections, other (leprosy, nontuberculous immunobiologics) mycobacterial infections) 1 Infuenza virus infection 3 Viral infections, miscellaneous (West Nile, Ebola, dengue 1 Lower respiratory tract infections fever) 1 Skin and sof tissue infections Musculoskeletal and Connective Tissue Disorders 1 Upper respiratory tract infections (e.g., otitis media, 1 Gout and hyperuricemia sinusitis, pharyngitis, bronchitis) 1 Osteoarthritis 1 Urinary tract infections, uncomplicated 1 Osteoporosis 2 Antimicrobial prophylaxis in surgery and other 1 Sof tissue injuries (e.g., strains, sprains, tendinitis, procedures bursitis, acute low back pain) 2 Antimicrobial stewardship 2 Rheumatoid arthritis 2 Bacterial resistance 3 Familial Mediterranean fever and other hereditary 2 Bloodstream and catheter infections autoinfammatory diseases 2 Bone and joint infections (e.g., osteomyelitis, prosthetic 3 Mixed connective tissue disease joint infections) 3 Myopathies (e.g., dermatomyositis, polymyositis) 2 Central nervous system (CNS) infections (e.g., 3 Reiter syndrome meningitis, encephalitis, brain abscess) 3 Rhabdomyolysis 2 Fungal infections, invasive (e.g., histoplasmosis, 3 Sjögren syndrome coccidioidomycosis, cryptococcosis, blastomycosis, 3 Spondyloarthritides (e.g., ankylosing spondylitis) hematogenous candidiasis, aspergillosis) 3 Systemic sclerosis 2 Gastrointestinal infections (e.g., infectious diarrhea, enterotoxigenic poisonings) 3 Vasculitides (e.g., polymyalgia rheumatica, temporal arteritis, granulomatosis with polyangiitis [Wegener 2 Health care–acquired infections: preventive measures granulomatosis]) 2 Hepatitis, viral Neurologic Disorders 2 Human immunodefciency virus (HIV) infection 1 Headache (e.g., tension-type, migraine, cluster) 2 Infections in immunocompromised patients (e.g., febrile 1 Pain, neuropathic (e.g., diabetic, postherpetic) neutropenia, opportunistic infections in AIDS) 1 Pain, nociceptive (acute and chronic) 2 Infective endocarditis 2 Epilepsy 2 Intra-abdominal infections (e.g., peritonitis, abscess) 2 Fibromyalgia 2 Microbiologic testing (including rapid diagnostic tests) 2 Multiple sclerosis 2 Parasitic diseases (e.g., protozoans [giardiasis, amebiasis, malaria, trypanosomiasis], helminths [nematodes, 2 Neurocognitive disorders (e.g., Alzheimer disease, schistosomiasis, trematodes, trichinellosis, cestodes], vascular and frontotemporal dementia) ectoparasites [head and body lice, scabies]) 2 Parkinson disease 2 Prostatitis 2 Sleep-wake disorders (e.g., narcolepsy, restless legs 2 Sepsis and septic shock syndrome, circadian