University Contacts University of Illinois at Urbana-Champaign Nathan Hoffmann, Director Office of Technology Management [email protected] otm.illinois.edu Laura Frerichs, Director University of Illinois Research Park [email protected] researchpark.illinois.edu University Breakthroughs Northwestern University Powering Change Alicia Loffler, Associate Vice President Research/Associate Provost for Innovation and New Ventures Innovation and New Ventures Office [email protected] invo.northwestern.edu University of Chicago Eric Ginsburg, Associate Director, Technology Commercialization Polsky Center for Innovation and Entrepreneurship [email protected] polsky.uchicago.edu University of Illinois at Chicago Suseelan Pookote, Director Office of Technology Management [email protected] otm.uic.edu Illinois Institute of Technology Catherine E. Vorwald, Associate Vice Provost Office of Technology Development [email protected] research.iit.edu/technology-development Hosted by AGENDAMORNING 8:30 Check-In Check-In Welcome & Opening Remarks: Mark Harris, President Welcome & Opening Remarks: Mark Harris, President 9:00 & CEO Illinois Science & Technology Coalition & CEO Illinois Science & Technology Coalition Network Security, Mobile Computing Breakthroughs in Oncology & Artificial Intelligence Wen-Mei Hwu (University of Illinois at Urbana-Champaign): Game Changing AI 9:20 - Jeffrey Hubbell (University of Chicago): Tumor-targeting Immunotherapies to 9:20 - and Block Chain Systems at the IBM-Illinois Center for Cognitive Computing Systems 9:40 Enhance Antitumor Efficacy and Reduce Adverse Events 9:40 Research (C3SR) 9:40 - Arnon Lavie (University of Illinois at Chicago): Structure-Based Design of Novel 9:40 - Aleksandar Kuzmanovic (Northwestern University): bloXroute: Scaling Blockchains 10:00 Therapeutic Agents by Prodrug Development and Enzyme Modification 10:00 by 1000X and Beyond 10:00 - Stephen Boppart (University of Illinois at Urbana-Champaign): Stain-Free Slide-Free 10:00 - Brighten Godfrey (University of Illinois at Urbana-Champaign): Continuous Network 10:20 Histopathology Platform with Biomarkers of Cancer 10:20 Verification and Congestion Control 10:20 - Vadim Backman (Northwestern University): Chromatin Regulation to Fight Resistance 10:20 - Heather Zheng (University of Chicago): Vulnerabilities in Social and Mobile Networks 10:40 in Cancer Chemotherapy 10:40 10:40 - Melody Swartz (University of Chicago): Lymphangiogenesis for Immunomodulation in 10:40 - Romit Roy Choudhury (University of Illinois at Urbana-Champaign): New Techniques 11:00 Cancer Therapy 11:00 in Mobile Computing and Their Applications 11:00 - Break 11:20 Break Frontiers in Neuroscience Materials by Design 11:20 - 11:20 - Mark Hersam (Northwestern University): Introducing the Memtransistor: John Rogers (Northwestern University): Skin-Interfaced Wearables for Clinical Health 11:40 11:40 A Potential Foundational Circuit Element for Neuromorphic Computing 11:40 - Richard Kraig (University of Chicago): Intranasal IGF-1 for the Treatment 11:40 - Paul Braun (University of Illinois at Urbana-Champaign): Paradigm Changing Materials 12:00 of Migraine 12:00 for Energy Storage 12:00 - Rashid Bashir (University of Illinois at Urbana-Champaign): Analysis of Blood and 12:00 - Dmitri Talapin (University of Chicago): Direct Optical Patterning of Inorganic Materials 12:20 Tissue Using Chip Scale Sensors 12:20 12:20 - 12:20 - Vikas Berry (University of Illinois at Chicago): Graphene and Other Nanostructures for Terry Vanden Hoek (University of Illinois at Chicago): Peptide Memetics of Cooling 12:40 12:40 Applications from Energy to Medicine AFTERNOON 12:40AGENDA - Lunch Lunch 1:40 Breakthroughs in Oncology Data Analytics & Robotics John Katzenellenbogen (University of Illinois at Urbana-Champaign): Inhibitors 1:40 - 1:40 - Michael Franklin (University of Chicago): Data Science, Systems, Distributed of FOXM1, a Key Driver of Many Cancers, and Orally Active Antiestrogens Effective in 2:00 2:00 Computing, and Big Data Recurrent, Endocrine-Resistant Breast Cancers 2:00 - Jennifer Wu (Northwestern University): Restoring Anti-Tumor Immunity: Targeting the 2:00 - Matthew Spenko (Illinois Institute of Technology): Robots That Climb 2:20 Immunosuppressive Molecule sMIC 2:20 and Perch 2:20 - Lev Becker (University of Chicago): A Novel Biologic for the Treatment of Many 2:20 - Kaiyu Guan (University of Illinois at Urbana-Champaign): Ecohydrology 2:40 Types of Cancer 2:40 and Remote Sensing 2:40 - Gregory Thatcher (University of Illinois at Chicago): Synthesis of Novel Compounds 2:40 - Kris Hammond (Northwestern University): Humanizing Data Through Natural 3:00 and Biomimetics for Probing of Biological Systems 3:00 Language Generation 3:00 - Ernst Lengyel (University of Chicago): CT45A Antigens for T-cell-based 3:00 - Mani Golparvar-Fard (University of Illinois at Urbana-Champaign): Visual Progress 3:20 Immunotherapies for Ovarian Cancer 3:20 Monitoring and Risk Management for Construction Projects 3:20 - Break Break 3:40 Frontiers in Neuroscience Social Good & Sustainability Rayid Ghani (University of Chicago) : Using Data Science and AI to Tackle Social 3:40 - Maria Siemionow (University of Illinois at Chicago): Novel Chimeric Cell Technology 3:40 - Issues in Public Health, Education, Criminal Justice, and Public Safety in the US as well 4:00 for Treatment of Rare Diseases 4:00 as Globally 4:00 - Joseph Moskal (Northwestern University): Glycogenes: Novel targets for Brain Tumor 4:00 - Amin Kohjin-Salehi (University of Illinois at Chicago): CO2 Conversion 4:20 Therapeutic Development 4:20 to Energy Rich Chemicals Using Inexpensive and Earth Abundant Catalytic System 4:20 - Euan Parnell (Northwestern University): Targeting Synaptic GEFs in Alzheimer’s 4:20 - Sammy Tin (Illinois Institute of Technology): Design Approaches for Advanced 4:40 Disease and Dementia 4:40 Materials and Processes 4:40 - Mary Jo LaDu (University of Illinois at Chicago): A Novel Alzheimer’s Disease 4:40 - Christopher Wolverton (Northwestern University): The Virtual Materials Laboratory 5:00 Biomarker in Human Plasma 5:00 5:00 - Networking Networking 6:00 Aptinyx Clarix Imaging A clinical-stage biopharmaceutical company A medical device company developing focused on the discovery and development innovative imaging hardware and software of transformative therapies for challenging to provide workflow-friendly solutions for This list includes start-ups affiliated with neurologic disorders. Aptinyx has a proven comprehensive surgical oncology. Clarix Imaging UPSfaculty presenters as well as those that platform for discovering compounds that work enables multidisciplinary clinical teams to will be available during the networking through a novel mechanism: modulation of improve the accuracy and efficiency in surgical reception ( denotes companies with NMDA receptors to enhance communication management of cancer. The company’s first table space). between neural cells. product is a compact, real-time, high-resolution 3D specimen imaging system for intra-operative Northwestern surgical margin assessment and for guiding American BioOptics Founder: Joseph Moskal gross pathologic evaluation. aptinyx.com Revolutionizing cancer screening with the University of Chicago introduction of the InPoint™ System, the first Founder: Xiaochuan Pan personalized cancer risk assessment to provide immediate and accurate results to identify high- bloXroute Labs risk patients that need further evaluation. Resolves the information propagation The first application of use is for colorectal ClostraBio bottleneck, allowing all nodes to maintain the cancer (CRC). consensus over the state of the blockchain, ClostraBio is a preclinical-stage pharmaceutical even when mining thousands of transactions company creating new medicines to prevent Northwestern per second, on-chain. bloXroute is a scalability life-threatening allergic reactions to food Founder: Vadim Backman solution which allows all cryptocurrencies and related diseases resulting from gut americanbiooptics.com and blockchains to scale to thousands of microbiome disruption. The company uses its transactions per second (TPS) on-chain, without capabilities to study the microbiome to identify changing their protocol. metabolites that are missing or depleted Anokion when the gut microbiome is disrupted, then Northwestern replace those metabolites using its propriety Anokion harnesses the power of natural immune Founder: Aleksandar Kuzmanovic polymer delivery platform to restore gut barrier equilibrium to develop solutions for antigen- bloxroute.com function. ClostraBio is applying this strategy to specific immune tolerance. The company develop drug candidates for food allergy and is focused on applying its antigen-specific inflammatory bowel diseases. immune tolerance technology to reduce the immunogenicity of therapeutic proteins and University of Chicago treat autoimmune diseases. Co-Founders: Cathryn Nagler & Jeffrey Hubbell Co-Founders: Melody Swartz & Jeffrey clostrabio.com Hubbell anokion.com START Diagnostic Photonics Dystrogen Therapeutics Enzyme By Design Fertility Basics Diagnostic Photonics provides hand-held, Dystrogen Therapeutics is a clinical stage Enzyme by Design focuses on providing Fertility Basics has developed a user-friendly high resolution optical and computed imaging regenerative medicine company focusing on safer cancer therapeutics for indications in App which accesses a complex algorithm for systems. The Foresee (4C) Imaging System rare diseases.