1 2 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Telencephalon Prosencephalon Optic vesicle Diencephalon Mesencephalon Metencephalon Rhombencephalon Myelencephalon Spinal cord (a) 4 weeks (b) 5 weeks Telencephalon Forebrain Diencephalon Mesencephalon Midbrain Pons Metencephalon Cerebellum Hindbrain Myelencephalon (medulla oblongata) Spinal cord (c) Fully developed 3 4 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Cerebral Rostral Caudal hemispheres Central sulcus Gyri Cerebrum Frontal lobe Lateral sulcus Central sulcus Temporal lobe Cerebellum Parietal lobe Brainstem Occipital lobe Spinal cord Longitudinal fissure (a) Superior view (b) Lateral view Precentral gyrus Central sulcus Postcentral gyrus Frontal lobe Parietal lobe Arachnoid mater Insula Temporal lobe Occipital lobe Cerebellum Blood vessels Medulla oblongata (c) Lateral view 5 c: © The McGraw-Hill Companies, Inc./Rebecca Gray, photographer/Don Kincaid, dissections 6 7 8 9 10 11 12 13 14 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Skull Dura mater: Periosteal layer Subdural space Meningeal layer Subarachnoid Arachnoid villus space Arachnoid mater Superior sagittal sinus Blood vessel Falx cerebri Pia mater (in longitudinal fissure only) Brain: Gray matter White matter 15 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Caudal Rostral Lateral ventricles Interventricular foramen Third ventricle Cerebral aqueduct Fourth ventricle Lateral aperture Median aperture Central canal (a) Lateral view 16 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Cerebrum Lateral ventricle Interventricular foramen Third ventricle Cerebral aqueduct Fourth ventricle Lateral aperture Median aperture (b) Anterior view 17 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Arachnoid villus 8 Superior sagittal sinus Arachnoid mater 1 CSF is secreted by choroid plexus in Subarachnoid each lateral ventricle. space Dura mater 1 2 CSF flows through Interventricular foramina into third ventricle. 2 Choroid plexus 3 Third ventricle 3 Choroid plexus in third ventricle adds more CSF. 7 4 Cerebral 4 CSF flows down cerebral aqueduct aqueduct to fourth ventricle. Lateralaper ture 5 Choroid plexus in fourth ventricle adds more CSF. Fourth ventricle 6 5 6 CSF flows out two lateral apertures and one median aperture. Median aperture 7 CSF fills subarachnoid space and bathes external surfaces of brain and spinal cord. 7 8 At arachnoid villi, CSF is reabsorbed into venous blood of dural venous sinuses. Centralcanal of spinal cord Subarachnoid space of spinal cord 18 19 20 21 22 23 24 25 26 27 28 29 30 31 .