Anti-Parkinsonian APIs and impurities Code Product CAS No. CS Price Unit Amantadine Hydrochloride NH 2 MM0564.00 Amantadine Hydrochloride 665-66-7 A 500mg HCl Apomorphine Hydrochloride OH H O MM0562.00 Apomorphine Hydrochloride Hemihydrate 41372-20-7 A 250mg HCl H2O 2 N H 2 Imp. B (EP) as Hydrochloride Trihydrate: Morphine N MM0037.00 6055-06-7 CS A 250mg H HCl H2O Hydrochloride Trihydrate 3 H O O O H Benserazide Hydrochloride N H H 2 N OH N HCl H MM1282.00 Benserazide Hydrochloride 14919-77-8 A 250mg O H O OH OH Benztropine Mesilate H O O H S MM1227.00 Benztropine Mesilate 132-17-2 A 250mg N O H O H Bromocriptine Mesilate Br H N O H O H N N N H N MM1159.00 Bromocriptine Mesilate 22260-51-1 A 100mg O O OH O O S OH Caramiphen Hydrochloride O N MM1585.00 Caramiphen Hydrochloride 125-85-9 A 50mg O HCl Carbidopa O OH H2 O MM1501.00 Carbidopa 38821-49-7 A 250mg H N H O N H2 OH Cycrimine Hydrochloride N HCl MM3046.00 Cycrimine Hydrochloride 126-02-3 A 100mg HO Diethazine Hydrochloride N N HCl MM1593.00 Diethazine Hydrochloride 341-70-8 A 50mg S Visit us at www.lgcstandards.com Anti-Parkinsonian APIs and impurities Code Product CAS No. CS Price Unit Entacapone O O N + MM1221.00 Entacapone 130929-57-6 A 250mg O N H O N OH N H O Imp. A (EP): (2Z)-2-Cyano-3-(3,4-dihydroxy- MM1221.02 145195-63-7 A 50mg H O O N 5-nitrophenyl)-N,N-diethylprop-2-enamide + N O O O O N + Imp. B (EP): Ethyl (2E)-2-Cyano-3-(3,4- O O MM1221.04 n/a A 50mg H O dihydroxy-5-nitrophenyl)prop-2-enoate N OH O H O MM1221.01 Imp. C (EP): 3,4-Dihydroxy-5-nitrobenzaldehyde 116313-85-0 A 100mg H O + N O O O O N+ Imp. D (EP): (2E)-2-Cyano-3-(3-ethoxy-4- O N MM1221.05 hydroxy-5-nitrophenyl)-N,N-diethylprop-2- 857629-79-9 A 50mg H O N enamide O O O + + N N MM1221.06 Imp. E (EP): 3,5-Dinitrobenzene-1,2-diol 7659-29-2 A 50mg O O H O OH O O N + Imp. F (EP): (2E)-2-Cyano-3-(3,4-dihydroxy- O OH MM1221.07 160391-70-8 A 50mg 5-nitrophenyl)prop-2-enoic Acid H O N OH O O N + Imp. G (EP): (2E)-2-Cyano-3-(3,4-dihydroxy- O N MM1221.08 n/a A 50mg H 5-nitrophenyl)-N-methylprop-2-enamide H O N OH O O Imp. H (EP): (2E)-3-(3,4-Dihydroxy-5-nitro- + N MM1221.03 phenyl)-2-(piperidin-1-ylcarbonyl)prop-2- 1150310-15-8 A 50mg O N H O N ennitrile OH O O + Imp. I (EP): Propyl (2E)-2-Cyano-3-(3,4- N MM1221.09 n/a A 50mg O O H O dihydroxy-5-nitrophenyl)prop-2-enoate N OH Levodopa O MM0262.00 Levodopa 59-92-7 A 500mg OH N H2 H O OH H O Imp. B (EP): (2S)-2-Amino-3-(4-hydroxyphenyl)propanoic N H2 MM0634.00 60-18-4 A 100mg OH Acid (Tyrosine) O O Imp. C (EP): (2RS)-2-Amino-3-(4-hydroxy-3- OH MM0262.05 methoxyphenyl)propanoic Acid (3-Methoxy- 7636-26-2 A 100mg N H 2 H O DL-tyrosine; (DL)-3-O-Methyldopa) O OH OH MM0262.06 4-Hydroxy-3-methoxymandelic Acid 55-10-7 A 100mg O H O O O MM0262.16 N,N-Dimethyl-L-phenylalanine 17469-89-5 A 100mg OH N Visit us at www.lgcstandards.com Anti-Parkinsonian APIs and impurities Code Product CAS No. CS Price Unit O O MM0262.17 (2S)-2-Amino-3-(3-methoxyphenyl)propanoic Acid 33879-32-2 A 50mg OH N H 2 Memantine Hydrochloride N H 2 MM1045.00 Memantine Hydrochloride 41100-52-1 A 250mg HCl OH MM1045.01 1-Hydroxy-3,5-dimethyladamantane 707-37-9 A 100mg Cl MM1045.04 1-Chloro-3,5-dimethyladamantane 707-36-8 A 100mg Br MM1045.05 1-Bromo-3,5-dimethyladamantane 941-37-7 A 100mg MM1045.06 1,3-Dimethyladamantane 702-79-4 A 100mg O N H MM1045.07 N-Formylmemantine 351329-88-9 A 100mg Metixene Hydrochloride HCl H O MM0125.00 Metixene Hydrochloride Monohydrate 7081-40-5 A 250mg S 2 N MM0125.01 Imp. A (EP): 9H-Thioxanthene 261-31-4 A 100mg S O Imp. B (EP): 9H-Thioxanthen-9-one MM0125.02 492-22-8 B 100mg (Thioxanthone) S Visit us at www.lgcstandards.com Anti-Parkinsonian APIs and impurities Code Product CAS No. CS Price Unit Orphenadrine Citrate O OH O OH MM3601.00 Orphenadrine Citrate 4682-36-4 A 250mg N O OH OH O Orphenadrine Hydrochloride HCl MM0801.00 Orphenadrine Hydrochloride 341-69-5 A 500mg N O Imp. A (EP): (RS)-(2-Methylphenyl)phenylmethanol MM0801.01 5472-13-9 A 100mg (2-Methylbenzhydrol) OH Imp. B (EP): (2-Methylphenyl)phenylmethanone MM0801.02 131-58-8 A 100mg (2-Methylbenzophenone) O Imp. C (EP) as Hydrochloride: (RS)-2-[(2-Methyl- MM0801.03 17752-32-8 A 50mg HCl N H 2 phenyl)phenylmethoxy]ethanamine Hydrochloride O Imp. D (EP) as Hydrochloride: Diphenhydramine HCl MM0490.00 147-24-0 A 500mg N Hydrochloride O Imp. E (EP) as Hydrochloride: (RS)-N,N-Dimethyl- 2-[(3-methylphenyl)phenylmethoxy]ethanamine MM0801.05 17630-53-4 A 100mg N HCl Hydrochloride (meta-Methylbenzyl Isomer O Hydrochloride) Imp. F (EP) as Hydrochloride: (RS)-N,N-Dimethyl- 2-[(4-methylphenyl)phenylmethoxy]ethanamine HCl MM0490.04 Hydrochloride (para-Methylbenzyl Isomer Hydro- 4024-34-4 A 100mg N chloride; 4-Methyldiphenhydramine Hydrochloride) O H HCl MM0801.07 N-Desmethylorphenadrine Hydrochloride 10488-36-5 A 100mg N O N-Ethyl-N,N-dimethyl-[2-(2-methylbenzhydryloxy)ethyl] + Cl MM0801.08 93940-17-1 A 100mg N ammonium Chloride O Phenglutarimide Hydrochloride H O N O N MM3210.00 Phenglutarimide Hydrochloride 1674-96-0 A 50mg HCl Pimavanserin Hemitartrat O N N H MM3578.01 Pimavanserin 706779-91-1 A 100mg F O N Visit us at www.lgcstandards.com Anti-Parkinsonian APIs and impurities Code Product CAS No. CS Price Unit Pramipexole Dihydrochloride Monohydrate H N S MM0332.01 Pramipexole Dihydrochloride Monohydrate 191217-81-9 A 250mg N H 2 HCl H2O N 2 Imp. A (EP): (6S)-4,5,6,7-Tetrahydro-1,3- H2 N S MM0332.02 106092-09-5 A 100mg N H 2 benzothiazole-2,6-diamine N Imp. A (EP) as Racemate: (6RS)-4,5,6,7-Tetrahydro-1,3- H2 N S MM0332.09 104617-49-4 A 100mg N H 2 benzothiazole-2,6-diamine N H Imp. D (EP): (6R)-6-N-Propyl-4,5,6,7-tetrahydro-1,3- N MM0332.07 104632-28-2 A 100mg S N H 2 benzothiazole-2,6-diamine N H2 N S MM0332.08 (6R)-4,5,6,7-Tetrahydro-1,3-benzothiazole-2,6-diamine 106092-11-9 A 100mg N H 2 N Pridinol Hydrochloride N HCl MM1177.00 Pridinol Hydrochloride 968-58-1 A 100mg OH N MM3493.01 1,1-Diphenyl-3-(N-piperidino)prop-1-ene Hydrochloride 30778-27-9 A 100mg HCl Procyclidine Hydrochloride H O MM1573.00 Procyclidine Hydrochloride 1508-76-5 A 100mg HCl N Ropinirole Hydrochloride H N Ropinirole Hydrochloride O MM0331.00 91374-20-8 A 250mg HCl available as Quantitative Standard LGCQUANT0331.00 N H N O MM0331.02 4-[2-(Dipropylamino)ethyl]indoline-2,3-dione Hydrochloride 221264-21-7 A 50mg HCl N O H N MM0331.08 4-(2-Hydroxyethyl)indolin-2-one 139122-19-3 A 100mg O H O Rotigotine Hydrochloride OH MM1403.00 Rotigotine 99755-59-6 A 100mg N S OH Despropylrotigotine ((6S)-5,6,7,8-Tetrahydro-6-[[2-(2- MM1403.02 153409-14-4 A 50mg thienyl)ethyl]amino]-1-naphthalenol) N S H O OH MM1403.03 (S)-2-Amino-5-methoxytetralin (S)-Mandelate 439133-67-2 A 100mg OH O N H 2 O MM1403.04 Despropylrotigotine Methyl Ether Hydrochloride 1232344-35-2 A 100mg HCl N S H Visit us at www.lgcstandards.com Anti-Parkinsonian APIs and impurities Code Product CAS No. CS Price Unit OH HCl MM1403.10 Rotigotine N-Oxide Hydrochloride n/a A 50mg + N S O Selegiline Hydrochloride MM0216.00 Selegiline Hydrochloride 14611-52-0 A 100mg N HCl Imp. A (EP) as Hydrochloride: (2RS)-N-Methyl-1- H phenylpropan-2-amine Hydrochloride ((RS)- N MM0964.03 300-42-5 CS A 100mg Metamfetamine Hydrochloride; rac-Methamphetamine HCl Hydrochloride) Imp. B (EP) as Racemate Sulfate:(2RS)-1-Phenylpropan- N H 2 O O MM0741.00 60-13-9 A 100mg S 2-amine Sulfate (rac-Amfetamine Sulfate; Amfetamine CS H O OH Sulfate) 2 Imp. C (EP) as Hydrochloride: (1RS, 2SR)-2- AND Enantiomer OH N H HCl MM0656.00 Amino-1-phenylpropan-1-ol Hydrochloride 154-41-6 A 500mg 2 (Phenylpropanolamine Hydrochloride) Imp. D (EP) as Racemate Hydrochloride: H N-[(1RS)-1-Methyl-2-phenylethyl]prop-2-yn-1- N MM0216.09 2588-96-7 A 100mg amine Hydrochloride (rac-Demethylselegiline HCl Hydrochloride) Tolcapone O MM3329.02 4'-Methyl-3,4-dihydroxybenzophenone 1391053-03-4 A 100mg H O H O O O MM3329.01 4-Hydroxy-3-methoxy-4'-methyl-5-nitrobenzophenone 134612-80-9 A 100mg H O + N O O Trihexyphenidyl Hydrochloride OH MM0237.00 Trihexyphenidyl Hydrochloride 52-49-3 A 500mg HCl N Imp.