Products and Services New Dietary Supplements Reference Standards Below is a list of newly released Reference Standards. Herbal Medicines/ Botanical Dietary Supplements Negundoside Vitex negundo Leaf Dry Extract Baicalein Baicalein 7-O-Glucuronide Scutellaria Baicalensis Root Dry Extract Non-Botanicals Dietary Supplements Compendium 2019 Edition Conjugated Linoleic Acids – Triglycerides (100 mg) In response to customer feedback, coupled with the evolving information needs in our digital world, we have moved Docosahexaenoic Acid the USP Dietary Supplements Compendium (DSC) to an online platform for the 2019 edition. It continues to provide Eicosapentaenoic Acid in-depth, comprehensive information for all phases of development and manufacturing of quality dietary Omega-3 Free Fatty Acids supplements including quality control, quality assurance, and regulatory/compendial affairs. L-alpha- Glycerophosphorylethanolamine Some of the advantages that come with the new, online platform include: L-alpha- Glycerylphosphorylcholine More frequent updates to ensure that you have access to the most current information Customizable alerts to notify you when selected documents are changed beta-Glycerylphosphorylcholine Creatine An intuitive interface to quickly and easily navigate to the information you need Creatinine A customizable workspace with bookmarks, alerts and a viewing history to help streamline your Reference Standards in development: online experience Botanicals Convenient, anytime, anywhere access with most, commonly used browsers Bitter Orange Fruit In addition to selected new and revised monographs and General Chapters from the USP-NF and Flavonoid Dry Extract Coptis chinensis Rhizome Food Chemicals Codex issued over the last three years, the DSC 2019 features: Dry Extract 24 new General Chapters Coptisine Chloride 72 new dietary ingredient and dietary supplement monographs Epicatechin 27 sets of supplementary information for botanical and nonbotanical dietary supplements Guarana Seed Dry Extract 59 updated botanical HPTLC plates Procyanidin B2 Revised and updated dietary intake comparison tables Non-Botanicals Updated Dietary Supplement Verification Program manual Annatto Seed Tocotrienols View this page for more information or to subscribe to the 2019 online DSC. Extract Hydroxocobalamin Chloride Pyrroloquinoline quinone Upcoming Events and Meetings Monographs Activity on Probiotics Standards Open for Public Comment until September 30, The probiotics Expert Panel, which reports to the Non-Botanicals Dietary Supplement Expert Committee, published 2019 an article entitled “Improving end-user trust in the quality of commercial probiotic products” in Frontiers in The standards below were Microbiology in April. qNMR Summit Returns to Rockville published in PF 45(4) for public comment on July 1, 2019 and will accept public feedback until September 30, 2019. To comment, please visit: To comment, please visit: USP- NF Pharmacopeial Forum New Monographs/General Chapters Calcium Magnesium Citrate Please join us on October 2-3 as the Fifth International Quantitative NMR Summit is returning to USP in Rockville, D-chiro-Inositol MD, three years after the highly acclaimed inaugural 2016 event. This summit will be open to everyone so that you Fish Oil Omega-3 Acid can prepare for the paradigm-shifting update to compendial analysis. The summit will assemble the leading-edge Ethyl Esters Concentrate qNMR practitioners from around the world. In the tradition of the original event, this summit will be co-organized Pummelo Peel with Center for Natural Product Technologies (CeNaPT) from the University of Illinois in Chicago (UIC). Further Pummelo Peel Powder details will appear shortly at the USP Research and Innovation and the UIC/CeNaPT websites. A free NMR Pummelo Peel Flavonoids Validation Workshop will be held at the conclusion of the qNMR Summit on October 4, hosted by Steelyard Dry Extract Analytics. USP offers discounted pricing for governmental and academic attendees. Registration is now open. Register Today! Revised Monographs/General Chapters For questions related to the qNMR Summit, please contact Anton Bzhelyansky, [email protected]. Asian Ginseng Root and Rhizome Past Events Asian Ginseng Root and Rhizome Powder Asian Ginseng Root and CPhI-China and HNC 2019 Rhizome Dry Extract June 2019 | Shanghai, China American Ginseng Root and Rhizome In June 2019, staff from USP participated in the Convention on Pharmaceutical Ingredients (CPhI) in China exhibiting, speaking and hosting workshops, namely the Sino-US Symposium on Natural Health Products cohosted American Ginseng Root with ChP. Presentations and discussions centered on dietary supplement, health food and herbal medicine and Rhizome Powder regulations, standards and quality requirements. American Ginseng Root and Rhizome Dry Extract L-alpha- Glycerylphosphorylcholine Cod Liver Oil Cod Liver Oil Capsules Standards Open for Public Comment until November 30, 2019 The standards below will be published in PF 45(5) for public comment on September 1, 2019 and will accept public feedback until November 30, 2019. To comment, please visit: http://www.usp.org/usp- nf/pharmacopeial-forum New Monographs/General In this same month, USP also exhibited at the Healthplex Expo and Natural & Nutraceutical Products China 2019 Chapters (HNC) where staff members were able to meet with stakeholders in the nutraceutical, health food, and dietary supplement industry providing information and education on relevant standards and quality verification programs. Bifidobacterium bifidium Bifidobacterium longum 2019 Dietary Supplements Stakeholder Forum subsp longum May 15, 2019 | Rockville, MD Lactobacillus reuteri Water-Soluble Vitamins Over 200 stakeholders participated in the USP Dietary Supplements Stakeholder Forum at the USP Headquarters in Rockville, MD. Gisele Atkinson, B.S., and Jim Griffiths, Ph.D., Council for Responsible Nutrition chaired the Preparation meeting on behalf of the stakeholder panel. Participants representing manufacturers, trade associations, service providers, and other interested parties who work with dietary supplements shared perspectives and provided direct Revised Monographs/General feedback on priority standards issues. USP staff provided updates about recently proposed new monographs, Chapters revisions and omissions in Pharmacopeial Forum. Aztec Marigold Zeaxanthin Several high-impact topics including label claim and overages, standards for hemp, limits for pesticide residues, Extract testing for food allergens, and probiotics were discussed. Stakeholders provided feedback on the role USP public Lactobacillus rhamnosus standards in the light of the FDA initiatives to modernize the dietary supplement regulations. HN001 Stakeholders were also encouraged to apply as expert volunteers through USP’s Call for Candidates process for Standards Open for Public the 2020-2025 cycle of USP Council of Experts. Detailed notes from the meeting and the speaker presentations are available here. Comment until January 31, 2020 The standards below will be published in PF 45(6) for public comment on November 1, 2019 and will accept public feedback until January 31, 2020. To comment, please visit: http://www.usp.org/usp- nf/pharmacopeial-forum New Monographs/General Chapters Sour Jujube Seed Sour Jujube Seed Powder Sour Jujube Seed Dry Extract Cranberry Fruit Juice Dry Extract Cranberry Fruit Juice Concentrate Pomegranate Fruit Dry Image 1: Gabriel Giancaspro, Vice President, Science-DS & Herbal Medicines, presenting a gift to thank Gisele Atkinson, B.S., and Extract Jim Griffiths, Ph.D., with Council for Responsible Nutrition for their role as chairs of the 2019 DS Stakeholder Forum Broccoli Seed Dry Extract Revised Monographs/General Chapters Cranberry Liquid Preparation 2750 MANUFACTURING PRACTICES FOR DIETARY SUPPLEMENTS New Monographs under Development Botanicals Ajowan Fruit Ajowan Fruit Powder Ajowan Fruit Dry Extract Cranberry Fruit Dry Juice Feverfew Leaf Extract Red Clover Tablets Image 2: Panel discussion held during the DS Stakeholder Forum White Peony Root White Peony Root Powder Participation in the International Conference on the Science of Botanicals (ICSB) 2019 White Peony Root Dry April 8-11, 2019 | Oxford, MS Extract Gastrodia elata Rhizome Staff from the Dietary Supplements and Herbal Medicines at USP participated in the International Conference on Gastrodia elata Rhizome the Science of Botanicals (ICSB) held in Oxford, Mississippi. The discussion at the conference focused on 25th Anniversary of DSHEA (The Dietary Supplement Health and Education Act of 1994) including reviewing the history, Powder confronting the issues, and discussing future aspects Gastrodia elata Rhizome Dry extract Our staff participated in the following sessions: Saposhnikovia divaricata Root Expert Panel Saposhnikovia divaricata Root Powder Pharmacopeial Standards as Tools to Assure Botanical Quality Saposhnikovia divaricata Root Dry Extract Nandu Sarma, Ph.D. and Gabriel Giancaspro, PhD, US Pharmacopeia (USP) Ulrich Rose, PhD, European Pharmacopeia (EP) Non-Botanicals Roy Upton, RH, American Herbal Pharmacopeia (AHP) Astaxanthin ester capsules beta-hydroxy-beta- G N Singh, PhD, and Vivekanandan Kalaiselvan, PhD, Indian Pharmacopeia (IP) methylbutyric acid (HMB) Calcium 3-hydroxy-3- De-an Guo, PhD, member, Chinese Pharmacopeia (ChP) methylbutyrate Choline Citrate The global supply chain and the adoption of several botanicals that were traditionally used as medicine, foods or dietary supplements around the world