France-Berkeley Fund Annual Report 2019-20 EXECUTIVE DIRECTORS EXECUTIVE COMMITTEE Randy Katz (2019-20) Vice Chancellor for Research; Larry M. Hyman Professor of Computer Science, UC Professor of Linguistics Jean-Baptiste Bordes Berkeley UC Berkeley Science & Technology Attaché, Consulate General of France in San Emmanuel Lebrun-Damiens Clément Sanchez Francisco Consul General of France in San Professor of Chemistry Francisco Collège de France Gaëtan Bruel Cultural Counselor, French Embassy Algance Mahdjoub in the United States Higher Education Communications PROGRAM MANAGER and Promotion Officer, Campus Denis Despréaux France Julia Nelsen, PhD Head of Mission, Délégation Institute of European Studies aux affaires européennes et Carlton R. Pennypacker UC Berkeley internationales, MESRI Guest Scientist, Lawrence Berkeley National Laboratory Jeroen Dewulf Professor of Dutch and German Robert Price Studies; Director, Institute of Professor Emeritus of Political European Studies, UC Berkeley Science; Former Associate Vice Chancellor for Research, UC Berkeley Juliette Donadieu Cultural Attachée, Consulate General Linda H. Rugg of France in San Francisco Associate Vice Chancellor for Research; Professor of Swedish Yves Frénot Literature, UC Berkeley Counselor for Science and Technology, French Embassy in the Jean Walrand United States Professor Emeritus of Computer Science, UC Berkeley Britt Glaunsinger Professor of Plant & Microbial Ting Xu Biology, UC Berkeley Professor of Chemistry and Materials Science and Engineering, UC Berkeley Julien Guy Project Scientist, Lawrence Berkeley National Laboratory

FRANCE-BERKELEY FUND 203 Moses Hall #2316 University of California, Berkeley Berkeley, CA 94720

+1 510 643 5799 [email protected] fbf.berkeley.edu FROM THE DIRECTORS

s the France-Berkeley Fund wraps up its twenty- The FBF acknowledges the many partners that make fifth year of supporting innovative research, we our work possible. We are grateful to the French Afind ourselves in a starkly different world than Ministry of Foreign Affairs, and the UC Berkeley Office the one we inhabited at our anniversary celebration last of the Vice Chancellor for Research, for their continued September. Since then, COVID-19 has rocked the globe, subsidies to the program. Sincere thanks go to the many overseas travel has been interrupted, and in-person reviewers at Berkeley and in France without whom the exchanges have given way to virtual encounters through annual evaluation process would not happen, and to our computer screens. At the same time, the killing of George dedicated Executive Committee. We also extend a warm Floyd and countless other Black Americans at the hands welcome to our newest member Jean-Baptiste Bordes of police has led to mass protests against systemic racial (Attaché for Science and Technology at the French discrimination, violence, and division, with calls for justice Consulate), and to Dr. Natalie Roe, Associate Director and reform echoing throughout the United States and of the Physical Sciences at Lawrence Berkeley National abroad. Laboratory, who joins the Committee in 2020-21.

While the unrest continues and the form of our During his visit to the Berkeley campus in January transatlantic interactions may be altered for some time, 2020—just a few months before the world turned upside what hasn't changed is the FBF's commitment to fostering down—French Ambassador Philippe Étienne called for collaborative networks across the disciplines. In spite of collective action and civic engagement among scientists the pandemic, we are pleased to support 15 new projects and scholars to address today's global challenges. Amid in 2020-21. As in years past, these collaborations span the upheavals we are facing, this need for cooperation is a broad range of topics and fields, including molecular felt more urgently than ever. The France-Berkeley Fund genetics, translation studies, robotics, sociology, remains steadfast in its mission to invest in collaboration linguistics, and more. and partnership, as France and the U.S. continue to work together and learn from each other. Our new cohort of grantees brings the total number of FBF-sponsored projects to nearly 500. Since its inception, Established in 1993 as a partnership with the French Ministry of Foreign Affairs, the the Fund has provided over $4.7 million in seed funding Sincerely, France-Berkeley Fund (FBF) promotes and supports scholarly exchange between for joint projects between Berkeley researchers and their colleagues at over 150 French institutions, while allowing Larry M. Hyman faculty and research scientists at the University of California and their counterparts scores of graduate students and post-docs to expand their Clément Sanchez in France. international connections. Supported teams have co- Executive Directors authored hundreds of publications and even launched new joint structures; the newest of these, CNRS Centre Pierre Julia Nelsen Through its annual grant competition, the France-Berkeley Fund provides seed Binétruy, builds on more than 20 years of Paris-Berkeley Program Manager money for innovative, bi-national collaborations in all disciplines. The Fund's core collaboration in cosmological physics. The results of a recent grantee survey in France reveal that 83% of FBF mission is to advance research of the highest caliber, to foster interdisciplinary projects have led to ongoing partnerships that continue inquiry, to encourage new partnerships, and to promote lasting institutional and well past the initial grant year, attesting to the enormous impact of the Fund over the last 25 years. A full summary intellectual cooperation between France and the United States. of the survey may be found in this report.

To further strengthen these ties, we are thrilled to announce that the Lawrence Berkeley National Laboratory has renewed its partnership with the FBF in 2020-21, with a contribution of $50,000 towards collaborative projects in the sciences. We are confident that the Lab's support will provide a strong foundation for continued growth, as we further develop the capacity to fund more groundbreaking research in the sciences.

4 | France-Berkeley Fund Annual Report 2019-20 NEWS CENTRE PIERRE BINÉTRUY

Dr. Alain Schuhl (Director general délégué à la science, CNRS) and Prof. Paul Alivisatos (UC Berkeley Exec. Vice Chancellor and Provost) sign the agreement establishing the Centre Pierre Binétruy on September 27, 2019. January 1, 2020 marked the official launch of the Pierre Binétruy International Research Laboratory, established jointly by UC Berkeley and the CNRS. The Center, named for the late Université Paris Diderot professor (1955-2017), builds on decades of successful collaborations in the areas of astroparticle and cosmological physics. Headed by Dr. RADEK From left: FBF Executive Committee members Emmanuel Lebrun-Damiens, Jeroen Dewulf, Julia Nelsen, Larry Hyman, Randy Katz, Juliette STOMPOR of the CNRS and Nobel Laureate SAUL PERLMUTTER—whose FBF collaborator Dr. REYNALD PAIN laid the Donadieu, and Jean-Baptiste Bordes (photo by Maxime Benallaoua) groundwork for this initiative in 2016—the Center will facilitate joint research between the Berkeley Department of Physics and IN2P3 (Institut National de physique nucléaire et de physique des particules). On September 5, 2019, the France-Berkeley Fund celebrated its 25th Anniversary. To mark the FBF@25 occasion, members of the FBF Executive Committee, UC Berkeley Deans, and new and former grantees convened for a festive gathering in the Durant Hall Atrium. French Consul General EMMANUEL LEBRUN-DAMIENS and UC Berkeley Vice Chancellor of Research RANDY KATZ made official remarks on the Fund's history and impact, emphasizing the importance of continued collaboration between France and the Berkeley campus. FRENCH AMBASSADOR VISITS To kick off 2020, the FBF was pleased to welcome PHILIPPE ÉTIENNE, the French Ambassador to the United States, on his first official visit to California. In his lecture to the campus community, organized by LBNL PARTNERSHIP the UC Berkeley Institute of Transportation Studies, Étienne called for French-American cooperation in the context of the 21st century We are thrilled to announce a new partnership in 2020- “fourth industrial revolution.” 21 between the France-Berkeley Fund and the Lawrence Berkeley National Laboratory. Joining the FBF Executive Committee to represent the Lab is Dr. NATALIE ROE, an internationally known physicist and observational cosmologist, and Associate Director of the Physical Sciences at LBNL. Roe joined Berkeley Lab in 1989 as a postdoctoral fellow and became Director of its Physics Division in 2012, overseeing a broad portfolio of projects including the Dark Energy Spectroscopic Instrument (DESI) at Kitt Peak, Arizona, and the dark matter experiment LUX-ZEPLIN in South Dakota. She has served on the DOE/NSF High Energy Physics Advisory Panel, the Fermilab Physics Advisory Council, and the National Science Foundation MPS Committee of Visitors. Roe is currently a Fellow of the American Association for the Advancement of Science and the American Physical Society, and was previously a member of the CERN Science Policy Committee and Chair of the APS Division of Particles and Fields. A champion of diversity and inclusion and career advancement opportunities, Roe is a founding member of Berkeley Lab’s Women Scientists and Engineers Council (WSEC) and an executive sponsor of the Lab’s Early Career From top: Ambassador Philippe Étienne addresses the UC Berkeley community in Sibley Auditorium (photo by Tom Lee/Berkeley Engineering); the Employee Resource Group. Dr. Natalie Roe Ambassador and representatives from the French Consulate in San Francisco with Berkeley faculty and researchers

6 | France-Berkeley Fund Annual Report 2019-20 Annual Report 2019-20 France-Berkeley Fund | 7 RECENT PROJECTS

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1 + 2 ANNA SERRA-LLOBET (Institute of International Studies, UC Berkeley) and JOHNNY DOUVINET (Université d'Avignon) convened a workshop on flood risk management at UC Berkeley in February 2020. The workshop included Prof. Renaud Vidal (Université Aix-Marseille) along with Berkeley co-PI John Radke, Berkeley faculty and researchers from the natural and social sciences, engineering, and the UC Berkeley Center for for Catastrophic Risk Management, as well as graduate students, postdoctoral scholars, and practitioners involved in land-use and flood management. 3 ELIZABETH ABEL (Department of English, UC Berkeley) and CLAIRE DAVISON (Université 4 Sorbonne Nouvelle - Paris 3) (FBF '19) organized a colloquium on “Sound Waves: Resonances of 4 MAGALI BARBIERI (Department of Demography, UC Berkeley) and HIPPOLYTE D'ALBIS (Paris School of Virginia Woolf” at UC Berkeley in Economics) have constructed two comparable databases of mortality indicators at the local level for France October 2019, with scholars and and for the United States. The goal of their project is to investigate the contribution of geographic variations students from the fields of English in mortality in diverging life expectancy trends between the two countries. The top image shows the U.S. literature, romance languages, and Human Mortality Database, available at usa.mortality.org. The bottom image is a screenshot of the Shiny App 3 sound studies. prototype built to visualize mortality information in the French database.

8 | France-Berkeley Fund Annual Report 2019-20 Annual Report 2019-20 France-Berkeley Fund | 9 5

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5 + 6 TRUMAN YOUNG (Department of Plant Sciences, UC Davis) and ELISE BUISSON (Avignon Université) Alpes) tested natural sandy shoal deposits and hydraulic fill material, in order to study the depositional organized a workshop on priority effects in restoration and invasive species control field experiments at the structure, strength, and stress-strain behavior of these materials. 9 PhD student GUILLAUME CHESNEAU Society for Ecological Restoration World Conference in September 2019. (Also pictured are collaborators (INRAe - Beaucouzé) and postdoctoral fellow LAUREN LUI (UC Berkeley/LBNL) helped make mutant libraries Manon Hess, Cara Nelson, Judith Sarneel, And Renaud Jaunatre.) Hess presented a session on ecological of bacterial isolates during a visit to Berkeley in spring 2019. With PIs ADAM ARKIN (QB3, UC Berkeley) and theory and invasive species management at the 13th Annual UC Davis Graduate Student Symposium in MATTHIEU BARRET (INRAe - Beaucouzé), the team has developed a synthetic community to reduce the Ecology in February 2020. 7 A recent paper co-authored by BENJAMIN WANDELT (Institut Lagrange de growth and transmission of bacterial pathogen Xanthomonas campestris in radish seeds. 10 The labs of TODD Paris) shows simulated data and mask choices used in the search for primordial gravitational waves in the DAWSON (Integrative Biology, UC Berkeley) and SYLVAIN DELZON (Université Bordeaux) seek to reconcile an Cosmic Microwave Background (CMB). 8 Using the 3-D X-Ray Computed Tomography device, collaborators ongoing debate about plant vulnerability to xylem embolism, examining the relationship between leaf or stem NICHOLAS SITAR (Civil & Environmental Engineering, UC Berkeley) and CINO VIGGIANI (Université Grenoble specific hydraulic conductivity and species distributions.

10 | France-Berkeley Fund Annual Report 2019-20 Annual Report 2019-20 France-Berkeley Fund | 11 UNCONVENTIONAL STEROID SIGNALING IN THE CHOROID PLEXUS: NEW COLLABORATIONS IMPLICATION IN TRAUMATIC BRAIN INJURY Polina LISHKO, Department of Molecular & Cellular Biology, UC Berkeley Dimitra GKIKA, Laboratoire de Physiologie celulaire, Université de Lille - Sciences et Technologies

Robotics Choroid plexus (CP) epithelia main function consists in producing and regulating cerebrospinal fluid (CSF). Such regulation is achieved through transepithelial The FBF is pleased to sponsor solute transport via plasma membrane ion channels and transporters. 15 projects in 2020-21, Interestingly, steroids and specially progesterone has been shown to exert potent Nutrition Data neuroprotective action. Since fluid secretion in CP is under control of ion channels with awards totaling $163,300 and transporters, we aim to explore whether progesterone can modulate Transient Receptor Potential channel activity directly in an unconventional manner meaning Poetry Ethics a rapid non genomic way. The outcome of this research may be of interest for treatment of CSF malfunctions such as traumatic brain injury. Transportation Engineering Mathematics Translation Studies Sociology Magnetics Law Integrative Biology ANALYSIS OF THE IMPACTS OF INFORMATION-BASED ROUTING ON CITY Psychology CONGESTION AND OPTIMAL REMEDIATIONS Linguistics Alexandre BAYEN, Institute of Transportation Studies / Department of Electrical Engineering and Computer Sciences, UC Berkeley Molecular & Cellular Biology Eric GOUBAULT, Informatique, École Polytechnique The goal of this project is to co-develop joint methods in the field of control/ Computer Science optimization and systems verification in the context of large-scale networks. The Physics project will apply the results to a specific problem in transportation engineering: the impact of traffic information on large scale mobility patterns in urban Evolutionary Biology environments. Specifically, it will analyze the recent impacts of routing apps such as Waze, Google maps, Apple traffic etc. on residential street congestion. Finally it will apply the findings to two cities, one in the US, Fremont, CA (in a joint partnership with UC Berkeley), and Neuilly sur Seine in France (through a Ministère de la Funded projects by area of research (2020-21 grant cycle) Transition écologique et Solidaire connection via École Polytechnique).

20% M3: MARVELOUS MICRO-MOTES

Kristofer PISTER, Department of Electrical Engineering and Computer Sciences, Exact Sciences UC Berkeley Applied Sciences Thomas WATTEYNE, EVA Team, INRIA Paris 47% Engineering 13% Micro-motes are a breakthrough technology which offers communication and Humanities computation capabilities in a single-chip design the size of a grain of rice. Our long- term vision is to use micromotes at the heart of micro-robots to form swarms Social Sciences of coordinated ant-sized micro-robots. These swarms can carry out missions in small and hard-to-reach places. One example is exploring and mapping the 13% internal structure of a collapsed building after an earthquake. A micro-mote has no stable crystal oscillator, only an unstable internal oscillating circuit. This requires 7% us to completely re-think time-keeping by using the network as a time source. This research changes the foundations of lowpower wireless and opens up new research domains on micro-motes and micro-robots. 12 | France-Berkeley Fund Annual Report 2019-20 Annual Report 2019-20 France-Berkeley Fund | 13 PHOTO-GENERATED MOLECULE-BASED MAGNETS LANGLANDS DUALITY AND SPECTRA OF QUANTUM INTEGRABLE SYSTEMS

David HARRIS, Chemistry, UC Berkeley Edward FRENKEL, Department of Mathematics, UC Berkeley Rodolphe CLÉRAC, CNRS / Centre de Recherche Paul Pascal, Bordeaux David HERNANDEZ, UFR de Mathématiques/IMJ-PRG, Université de Paris

This project aims to develop molecule-based permanent magnets through a The category of finite-dimensional representations of a quantum affine algebra combination of chemical synthesis and photomagnetism. This work will leverage is one of the most studied objects in quantum groups theory with remarkable and combine the expertise in the synthesis of molecule-based magnets of co-PI applications in various branches of Mathematics and Physics. However many Dr. D. Harris, a project scientist at the University of California, Berkeley (UCB), with important and fundamental questions remain unsolved in this field. The aim of the expertise in photomagnetism of co-PI Dr. R. Clérac, a CNRS researcher at the this research project is to make advances in the understanding of the category as Centre de Recherche Paul Pascal (CRPP) in Bordeaux. In addition to the scientific well as of its applications to quantum integrable systems and in the context of the goals, we expect this project will provide a rich intellectual experience for the Langlands program. involved students, by both affording them expertise in a new area of science and the opportunity to mentor a visiting student, and will bring new knowledge bases to UCB and CRPP in order to broaden the research scopes of the two institutions.

EVOLUTION OF GUSTATORY PREFERENCES IN HERBIVOROUS INSECTS MECHANISM OF HOMOLOGY SEARCH DURING GENETIC RECOMBINATION Noah WHITEMAN, Integrative Biology, UC Berkeley Wolf-Dietrich Heyer, Microbiology and Molecular Genetics, UC Davis Frédéric MARION-POLL, Evolution, Génomes, Comportement, Ecologie (EGCE), Aurèle Piazza, Laboratoire de Biologie et Modélisation de la Cellule (LBMC), AgroParisTech École Normale Supérieure de Lyon Plant-feeding insects are extraordinarily diverse as a result of their co- Homologous recombination is a universal DNA break repair mechanism that diversification with their host plants over 400 million years. One of the major uniquely employs an intact homologous DNA molecule as a template for repair. adaptations necessary for herbivorous feeding is the ability to preferentially feed Despite its importance for genome maintenance, the basic mechanism by which on the appropriate host plants, but how taste evolves in herbivorous insects is not this homologous molecule is identified amidst the genome remains elusive. We well understood at molecular genetic and neurophysiological levels. Our research tackle this fundamental gap in our understanding of homologous recombination, project will closely examine how chemoreceptors expressed in the peripheral as well as the poorly characterized role in this process of conserved protein of nervous system have evolved to change neural responses, and how this ultimately clinical significance. To this end, we combine in vitro protein biochemistry (Heyer shifts behavioral responses to toxic plant compounds from aversion to attraction. lab) and novel physical assays to monitor intermediates and steps of the repair This research takes an integrative approach combining behavioral experimentation, reaction in cells (Piazza lab). comparative genetic analyses, and electrophysiology.

THE EVOLUTION OF SPECIFICITY IN PARALLEL PATHWAYS OF SIGNALING CYLINDRIC PARTITIONS IN ANIMAL CELLS Sylvie CORTEEL, Mathematics, UC Berkeley John KURIYAN, Chemistry / Molecular & Cellular Biology, UC Berkeley Jérémie BOUTTIER, Institut de physique théorique, CEA Saclay / Laboratoire de Jacqueline CHERFILS, Laboratoire de Biologie et Pharmacologie Appliquée, physique, École Normale Supérieure de Lyon CNRS / École Normale Supérieure Paris-Saclay This research project is at the interface between enumerative combinatorics and Small GTPases are small protein switches that cycle between ON states and OFF mathematical physics. It is centered on cylindric partitions, which are combinatorial states and are key stop or go deciders in many important cellular tasks, such as objects that are connected with different fields: hypergeometric identities, string growth or death. There are many distinct versions of these proteins in cells, each theory, probability theory and nonequilibrium statistical physics. with a specific task or pathway. This project will investigate why proteins that interact with a GTPase in one pathway are specifically paired to their distinct GTPase and do not cross talk with GTPases in other pathways. This is a key unanswered question of major biomedical importance.

14 | France-Berkeley Fund Annual Report 2019-20 Annual Report 2019-20 France-Berkeley Fund | 15 A SYSTEM BIOLOGY APPROACH TO UNDERSTAND THE HEALTH BENEFITS THE LEGALIZATION OF ORGANIZATIONAL LIFE IN FRANCE AND THE OF POLYPHENOLS UNITED STATES: TENSIONS BETWEEN INDIVIDUAL RIGHTS AND THE COLLECTIVE GOOD Patricia OTEIZA, Department of Nutrition, UC Davis Dragan MILENKOVIC, Unité de Nutrition Humaine, INRAE, Université de Calvin MORRILL, Department of Sociology / School of Law, UC Berkeley Clermont Auvergne Jérome PÉLISSE, Département de Sociologie / Centre de sociologie des organisations (CSO), Sciences Po Paris This new trans-Atlantic collaborative network will aim to answer questions regarding the health effects of polyphenol consumption on cardiometabolic Project participants will contribute to a grounded theoretical framework along two health. We aim to evaluate the capacity of polyphenols to prevent dysfunctions dimensions: a macro-sociolegal analysis of the relationship between ideas about induced by western-type diet consumption that result in the development of CVD rights and the collective good in two different legal systems (civil law in France and and metabolic diseases. Our project will initiate scientific exchanges aiming to common law in the United States) and systematic analyses of ideas about rights define a new research strategy on polyphenols and human health by performing and the collective good via paired-comparisons of organizations in different sectors integrated system biology analyses of existing knowledge but also by using mutual across the two countries, specifically private corporations, public schools and knowledge more integrated analyses of results that are being obtained in ongoing urban housing agencies, and non-profit religious organizations. projects in both laboratories.

THE FUNCTION AND HISTORICAL EVOLUTION OF AUGMENTS IN THE THE EMERGENCE OF PUBLIC CONTROVERSIES IN SCIENCE, TECHNOLOGY & BANTU LANGUAGES MEDICINE: A NEW METHODOLOGICAL PARADIGM

Peter JENKS, Department of Linguistics, UC Berkeley Elena CONIS, Graduate School of Journalism, UC Berkeley Mark VAN DE VELDE, Langage, Langues et Cultures d'Afrique Noir, CNRS / Laura DRAETTA, Télécom Paris Graduate School of Engineering, IP Paris Institut national des langues et civilisations orientales (Inalco) Our project offers an empirical study of public controversies regarding science, This project aims at gaining insight into the augment, a mysterious grammatical technology and medicine. We focus on emblematic case studies in environmental element found in the Bantu languages of Africa. The role of the augment has been ethics (pesticides), bioethics (vaccines), data ethics (facial recognition) and compared to that of a definite article in English or French, but this comparison innovation ethics (smart meters). Our study aims to develop an integrated is at best an approximation. We will approach the topic from the different methodological paradigm for analyzing public controversies regarding science, theoretical and methodological perspectives of synchronic generative grammar technology and medicine and theorizing the role of the the media, scientific and historical linguistics. community and government policy in determining the course and outcome of such controversies.

TRANSLATION OF POETRY: INTERDISCIPLINARY PERSPECTIVES THE EFFECT OF CULTURE ON INDIVIDUAL PERCEPTUAL MECHANISMS

Timothy HAMPTON, Department of Comparative Literature, UC Berkeley David WHITNEY, Department of Psychology, UC Berkeley Daniel HENKEL, Université Paris 8, Vincennes - Saint-Denis Mark WEXLER, Integrative Neuroscience and Cognition Center, CNRS / Université de Paris Long thought as something humanists did in the margins of their other work, it has now become clear that both the practice and the theory of translation The goal of our project is to examine how culture, as represented by language, can are central to the role of the humanities as we move into an increasingly multi- affect low-level perceptual function--in our case hearing. Although studies of low- cultural global culture, and as new technologies reshape how we use language. level perception have assumed that it is largely universal, there have been reports This project involves organizing a workshop to study the intersection of literary that lower-level perceptual function varies between cultures. Here we put forward form and history--manifested in poetry--with the disciplines of linguistics and and test the hypothesis that the effect of language milieu on perception is via a translation studies. We will collaborate on panels and discussions about the process called ensemble perception. linguistic, literary, philosophical, and cultural problems involved in the translation of poetry, and on translation as a conceptual node in the re-imagination of the humanities.

16 | France-Berkeley Fund Annual Report 2019-20 Annual Report 2019-20 France-Berkeley Fund | 17 FBF IMPACT SURVEY Proposals received vs. funded projects, 2008-2012 Social Science

Institut Pasteur Collège de INRIA Engineering From February to May 2020, the INSERM IRD 2% France 2% 2% CIRAD Office for Science and Technology of 1% 1% 2% Exact Science the Embassy of France in the United ENS States conducted a survey among 2% Arts & Humanities past France-based FBF grantees to CEA measure the program's scientific 3% Natural & Applied Sc. impact over the past ten years (2008- INRAE 18). Yves Frénot and Carrina Lacorata 4% 0 50 100 150 200 coordinated the survey, with the ABOUT THE collaboration of Christophe Delacourt Funded Proposals received and Robert Gardette (French Ministry University PROJECTS of Higher Education, Research and Engineering School 35% Innovation) and of FBF Program 6% Proposals received vs. funded projects, 2013-2018 Manager Julia Nelsen. The following are key results presented at the FBF Social Sciences Executive Committee Annual Meeting Physics/Math/CS in June 2020. CNRS Engineering 29% Medicine/Public Health • Target: French Principal 29% Law/Business Investigators of 235* projects Average of projects funded Other Education funded 2008-18 10% vs. proposals received *243 projects in total; 235 Exact Science (2008-18) questionnaires sent Arts & Humanities Natural & Applied Sc.

• Average response rate: 46% (109 Institutions 0 20 40 60 80 100 120 140 of 235 grantees surveyed) Funded Proposals received ABOUT THE FRENCH GRANTEES $10k Previous FBF Average funding per project Chateaubriand 11% Previous collaboration 11% with a US partner? France-Stanford Center 6% Fulbright Yes France-Chicago 11% 46 Masters students 29% Center 6% involved in 32 projects France-MIT Seed NSF 74 PhD students >> Funds 6% 9% involved in 50 projects No 71% 104 Post-docs Other involved in 70 projects 40%

18 | France-Berkeley Fund Annual Report 2019-20 Annual Report 2019-20 France-Berkeley Fund | 19 SCIENTIFIC PRODUCTION (2008-17)* Type of collaboration after initial grant year *Projects begun in 2018 not considered; data based on 95 funded projects 83% 76%

of FBF projects 50% 51% continued past initial grant year 32% 21% 23% 9% 4% 1%

• IRL (ex UMI), Centre Pierre Binétruy, in the area 38.1 62% 3 of cosmological and astroparticle physics Overall average annual of funded projects led to at new joint structures • IRN (ex GDRI) QUADMARTS - Quantitative number of co-publications least one co-publication created through FBF Detection of Molecular And Radical Trace Species collaborations • Inria-EVA (with Prof. Steven Glaser’s team at UC Berkeley) through REALMS associate team Percentage of co-publications per scientific domain (2008–17)

5% 11% 2% 8% Positions for junior researchers secured thanks to FBF projects Mathematics Researcher in a public research Physics 6% institution (permanent 17% Marine / Planetary / Earth Sciences position) 76% 13% Chemistry Teacher/Researcher of respondents believe the 25% (permanent position) FBF had a positive impact Biology / Health on the career paths of 22% Humanities Postdoc/Teacher/Researcher junior researchers Engineering 17% (temporary position) Information Technology Employed in a private Agronomy / Ecology company with links to research field 8% 10% 47% Other 9%

20 | France-Berkeley Fund Annual Report 2019-20 Annual Report 2019-20 France-Berkeley Fund | 21 PROJECT REPORTS FINAL REPORTS 2018-19

Project #1-2018 synthetic community. Before the beginning of the current project, we found that UC PI: Adam Arkin (QB3 - California Institute for exploitative competition (i.e. resource overlap) between Quantitative Biosciences, UC Berkeley) Xcc 8004 and seed-borne bacterial was assessed on seed France pi: Matthieu Barret (IRHS/EMERSYS, INRAe - exudates medium. Under our experimental conditions, Beaucouzé) two strains of the bacterial species Stenotrophomonas PROJECT TITLE: Engineering a pathogen-resistant seed rhizophila significantly decreased Xcc population size, microbiome probably as a result of high overlap in resource use MONTH/YEAR OF AWARD ACTIVATION: November 2018 (Torres-Cortes et al., 2019). However, when these two bacterial strains were inoculated on seed, seed to seedling 1) Describe the work accomplished, in relation to the transmission of Xcc 8004 was limited. In the current original project description. project, we increased the number of bacterial strains in the initial seed inoculum. This synthetic community The original project description was to design a bacterial applied on seedling significantly reduced Xcc population synthetic community to limit the transmission of size on seedling (Figure 1). This phenomenom is partly the bacterial pathogen, Xanthomonas campestris pv. explained by the wider range of resources used by the campestris (Xcc), in radish seeds and to reveal the genetic different strains, which therefore limit Xcc 8004 growth. and ecological mechanisms that confer resistance. We In addition to exploitative competition, we have been successful in designing a synthetic community assessed if interference competition (secondary that reduces the growth of the Xcc 8004 strain and we metabolite production) could also explain the decrease understand some of the ecological mechanisms that of Xcc population size on seedlings. Using a method confer this resistance. The shelter-in-place orders due developed by Dr. Lui, we analyzed the impact of cell- to the COVID-19 pandemic have halted our lab work, but free supernatant of the selected bacterial strains on once we are back in lab we plan to finish investigating the Xcc 8004 growth. The culture-free supernatant of one ecological and genetic mechanisms of how the synthetic bacterial strain of Pseudomonas fluorescens increased community inhibits the growth of Xcc. the generation time of Xcc 8004 by 2-fold. While we are To design the bacterial synthetic community still investigating the exact nature of these compounds that reduces the growth of Xcc 8004, we assessed the through metabolomics, the production of these interactions between Xcc 8004 and 33 bacterial strains compounds is specifically triggered by Xcc and other isolated from radish seeds. These strains were selected Xanthomonadales species. from a collection of approximately 1,000 strains according To study the genetic mechanisms of how the to their abundances in the radish seed microbiota synthetic community inhibits the growth of Xcc, we (Rezki et al., 2018) and their phylogenetic diversity. We used a mutant library of Xcc 8004 created by our other explored using the ecological mechanisms of exploitative collaborators, Dr. Adam Deustchbauer and Dr. Alice competition and interference competition to create the Boulanger. By exposing the mutant library to spent media,

Annual Report 2019-20 France-Berkeley Fund | 23 FINAL REPORTS FINAL REPORTS 2018-19 2018-19

we were able to study which genes confer susceptibility collaborating beyond this project. dimensions of their metabolic diversification. We The award was primarily spent to reimburse travel of Xcc 8004 to compounds produced by members of the This fund allowed us to travel to visit each other expect that our collaborative project, once published, expenses for the American team on two trips to the synthetic community. The mutant library data indicated and learn experimental methods in-person. In 2018, Dr. Lui will constitute a substantial contribution to the rapidly Institut Pasteur, and for one trip by the French team to that likely a siderophore produced by a Pseudomonas visited the Barret Lab at INRAe to start optimizing the use developing field of CPR biology and spur additional Berkeley. Pending the re-opening of UC Berkeley facilities, species in the synthetic community is partially responsible of transposon mutant libraries on seeds and to see how work both in our own groups and also in those of other we will also use a portion of the award to aid with for the inhibition of Xcc. Rescue experiments using iron the Barret lab conducts their bacteria-seed experiments. researchers. generation of data for an additional paper pertaining to and manganese supported these hypotheses. Once we are She also gave a seminar on her research. In late April the collaboration between our groups. We will likely seek back in the lab we will continue with these experiments to / early May 2019, Dr. Barret and his graduate student 2) Give the names and ranks of all project additional funding to support this work from a national or confirm the genes that cause the susceptibility of Xcc to Guillaume Chesneau visited to help make mutant libraries participants. international agency. We greatly appreciate the support of metabolites that the Pseudomonas species is producing. of the bacterial isolates. Dr. Barret also gave a seminar on the FBF in this exciting and productive collaboration. his lab’s research during the visit. We anticipate applying Alexander Jaffe, doctoral student (UCB) 2) Give the names and ranks of all project participants. our findings to other synthetic community studies to Cindy Castelle, senior scientist (UCB) understand microbial interactions and how to apply Paula Matheus Carnevali, postdoc (UCB) Adam Arkin, Professor, UC Berkeley synthetic communities in agriculture. Simonetta Gribaldo, Head of Unit (Pasteur) Lauren Lui, Postdoctoral Fellow, UC Berkeley / Lawrence Jill Banfield, Professor (UCB) Project #5-2018 Berkeley National Lab 5) Give a final accounting of how the France-Berkeley Andrew Hendrickson, Research Associate, Lawrence Fund award was spent. Do you envision soliciting 3) List all publications resulting from this project. UC PI: Louise Berben (Chemistry, UC Davis) Berkeley National Lab additional outside funding for this or related projects Include journal titles and issues/dates. france pi: Marc Robert (Chimie, Univ. Paris Diderot) Trenton Owens, Research Associate, Lawrence Berkeley in the future, and if yes, from where? PROJECT TITLE: Exploring Photocatalytic CO2 Reduction National Lab Jaffe AL, Castelle CJ, Matheus Carnevali PB, Gribaldo S, to Fuels with Small Molecular Iron Clusters Yujia Liu, Undergraduate, UC Berkeley We spent approximately $1900 when Dr. Lui visited Dr. Banfield J. The rise of diversity in metabolic platforms MONTH/YEAR OF AWARD ACTIVATION: December 2018 Matthieu Barret, Scientist, INRAe - Beaucouzé Barret’s lab at INRA in 2018, and another ~$2500 for Dr. across the Candidate Phyla Radiation. In press at BMC Gloria Torres, Postdoctoral Fellow, INRAe – Beaucouzé Barret and Mr. Chesneau’s visit to UC Berkeley in 2019. Biology. 1) Describe the work accomplished, in relation to the Guillaume Chesneau, Graduate student, INRAe - Approximately $4100 has been spent on supplies for original project description. Beaucouzé. sequencing, sending materials between labs, and growing 4) Comment on the collaborative nature of this cultures and plants. We anticipate spending the rest of the project, highlighting aspects that have fostered A student from PI Berben’s lab travelled to Paris Diderot in 3) List all publications resulting from this project. FBF grant money on supplies on mutant library creation, continuing relationships between French institutions February 2019 and during his three week stay he worked Include journal titles and issues/dates. metabolomics analysis, and high-throughput sequencing and UC campuses. Will future collaboration occur as a with a student in PI Robert’s group to investigate the runs. We anticipate applying for other sources of funding result of this project? photocatalytic reactivity of the Berben lab iron cluster After the shelter-in-place orders are lifted and we are able for our collaboration, such as the Thomas Jefferson Fund catalyst and its ability to reduce CO2 or CO into fuel- to resume lab work, we will finish our experiments and and European Research Council grants. The project has been an extremely collaborative effort so type products such as formate or methanol. The catalyst anticipate publications on these topics: far, encompassing the exchange of data, methodological was studied under a variety of reaction conditions 1. Using synthetic communities to reduce the growth of expertise, and advising between the French and American that included variation of the solvent, headspace gas, pathogen Xanthomonas campestris pv. campestris and to Project #2-2018 teams. In particular, the American doctoral student photosensitizer, and reaction time, and those initial discover mechanisms involved in seedling transmission Alexander Jaffe has benefitted immensely from technical experiments point to potentially interesting results using 2. Pyoverdine-like production in Pseudmonas is triggered training in phylogenomics and additional advising from [Ru(bpy)3]2+ as photosensitizer in MeCN solution with by exposure to Xanthomondales species UC PI: Jillian Banfield (Earth & Planetary Science, UC Dr. Simonetta Gribaldo and her laboratory members. As Berkeley) CO gas included to provide extra stabilization for the we have previously reported, Dr. Gribaldo has applied for catalyst. At this point, the project is moving according 4) Comment on the collaborative nature of this france pi: Simonetta Gribaldo (Institut Pasteur, Paris) and received the UC Berkeley Miller Visiting Professorship PROJECT TITLE: Combining genome-resolved to the original timeline and the survey of the catalyst project, highlighting aspects that have fostered during which we she will continue to work closely with reactivity has been almost completed as described in continuing relationships between French institutions metagenomics and phylogenomics approaches to the Banfield Lab on campus. Although delayed due to the unravel the diversity and evolution of the Candidate the proposal. So far, no conclusive results or detailed and UC campuses. Will future collaboration occur as a current pandemic, we anticipate that this visit (when it mechanistic studies have been fully completed. result of this project? Phyla Radiation (CPR) bacteria does occur) will continue to strengthen the connections MONTH/YEAR OF AWARD ACTIVATION: 2018 PI Berben has visited Paris where she attended the Cyclic between our groups and allow us to work together on Voltammetry International School for 1 week at Paris This project allowed our two labs to combine the several additional projects. These projects will build upon Diderot, and she presented invited seminars at four 1) Describe the work accomplished, in relation to the synthetic biology and high-throughput genetics expertise on our already completed BMC Biology study to further universities and participated in Robert group lab meetings. original project description. of the Arkin lab and the plant microbiology and seed explore the evolution and ecology of CPR bacteria. PI Robert visited UC Davis for one week during October microbiota expertise of the Barret lab. Together we have 2019. He presented research seminars at UC Davis, We have accomplished the major aims of our original developed a synthetic community that has promise to 5) Give a final accounting of how the France-Berkeley Department of Chemistry and at the Joint Center for project description as manifested in the below paper, reduce the prevalence of a seed pathogen. Once we are Fund award was spent. Do you envision soliciting Artificial Photosynthesis at Lawrence Berkeley National recently accepted by the peer-reviewed journal BMC back in the lab, we hope to continue to use the mutant additional outside funding for this or related projects Lab. He also presented 2 three hour classes covering Biology. In this work, we successfully resolved the libraries to understand the genetic underpinnings of the in the future, and if yes, from where? homogeneous electrochemistry and electrocatalysis to phylogeny of the CPR and investigated the evolutionary microbial interactions we see. Our labs plan to continue students faculty at UC Davis. 24 | France-Berkeley Fund Annual Report 2019-20 Annual Report 2019-20 France-Berkeley Fund | 25 FINAL REPORTS FINAL REPORTS 2018-19 2018-19

Project #6-2018 the wild type optical maps was 4.8 and 5.4Gb in size, 2) Give the names and ranks of all project respectively. By aligning the 2 optical maps against the Peter Stokes: Doctoral Student participants. UC PI: Benjamin Blackman (Plant and Microbial Biology, reference genome, we determined the source of this Melis Akman: Postdoctoral Scholar UC Berkeley) size discrepancy was the high degree of heterozygosity Benjamin Blackman: Assistant Professor - Louise Berben (Professor, UC Davis) france pi: Helene Berges (CNRGV-INRA, Toulouse) in both the landrace and wild samples, as shown by William Marande: Research Assistant (ingénieur de - Marc Robert (Professor, University Paris Diderot) PROJECT TITLE: Examining the history and impact of multiple optical map contigs aligning to one reference recherche) - Cody Carr (Graduate Student, UC Davis) gene content variation in sunflower genome region. This result was not surprising due to the Isabelle Dufaut : Research Assistant (ingénieur de - Martin Kientz (Graduate Student, University Paris MONTH/YEAR OF AWARD ACTIVATION: July 2018 known heterozygosity of these accessions. However, the recherche) Diderot) alignment revealed that only 70 % of the ref genome was Helene Berges: Core Director - PI’s Berben and Robert interacted directly with all 1) Describe the work accomplished, in relation to the present in the landrace optical map and more remarkably, 3) List all publications resulting from this project. graduate students and postdocs in the host institutions original project description. only 12 % of the reference genome aligned to the wild Include journal titles and issues/dates. groups during the exchange visits. sunflower sample’s optical map. This result, which is The aim of our proposal has been to develop genomic often the case in plant genomes with large genome sizes, N/a 3) List all publications resulting from this project. resources that will allow us to examine structural variation revealed the high level of divergence between the wild Include journal titles and issues/dates. in the genomes of wild and domesticated sunflower, with population genome sequence and the domesticated 4) Comment on the collaborative nature of this the ultimate goal of examining how this variation may have genotypes, indicating that high single nucleotide variation project, highlighting aspects that have fostered None yet. been impacted by the domestication process. During our and structural variations leading to presence/absence continuing relationships between French institutions project, we made progress on developing optical maps as of whole genome segments creates a major challenge and UC campuses. Will future collaboration occur as a 4) Comment on the collaborative nature of this well as advancing resources that will improve their utility for finding synteny between genome assemblies by this result of this project? project, highlighting aspects that have fostered and connection to domestication. method. continuing relationships between French institutions Specifically, ultra-high molecular weight DNAs Because heterozygosity is a common problem in To improve the feasibility of the project and to and UC campuses. Will future collaboration occur as a (uHMW DNAs) were extracted and optical maps were assembling and understanding plant genomes, we have characterize copy number and presence/absence variants result of this project? constructed from one landrace (Arikara) and one developed tools in order to understand which optical map in regions that experienced selective sweeps during wild type (NB1/Ann1238) sunflower. In the course of contigs can be combined into the same allelic scaffolds. domestication, it will be important to sequence several Remaining photocatalysis experiments using catalysts analyzing that data, new computational methodologies This approach will help the assembly of heterozygous sunflower genomes. Because the Ann1238 genome prepared at UC Davis will be pursued at University of for distinguishing the two allelic sequences from each genomes in general. During this development we assembly did not yield scaffolds of sufficient lengths Paris Diderot. These remaining experiments include highly heterozygous individual were advanced. The compared the 2 copies of the genomes and we observed and similarity to the XRQ reference genome for robust investigation of water as a solvent system, and the use of sunflower reference genome (XRQ, an elite oilseed line) that the 2 allelic copies had less % of identity than the optical map alignment, long reads will be needed to CO and CO2 gas mixtures in stabilization of the cluster. has had a revision during this period, which facilitated global optical map compared to the reference genome. complete a better assembly. The Blackman lab is currently Development of photosensitizers suitable for use in better comparisons to highlight true structural variants For example, the chromosome 17 of the reference genome writing a proposal to the International Consortium for aqueous media is also ongoing to facilitate the cluster between the reference and these samples as well as other is 80 % similar with the chromosome 17 of the landrace Sunflower Genomics, a public-private partnership of reactivity. optically mapped elite varieties. In addition, we performed genome but only 40 % of the allele 1 is similar with the which the CNRGV is the keystone public partner. Part of additional sequencing of an individual from the same wild allele 2 for the chromosome 17. the proposed work by the consortium will be to advance 5) Give a final accounting of how the France-Berkeley population as the individual we have optically mapped These surprising results represent a new view of a this goal and several other wild reference genomes and Fund award was spent. Do you envision soliciting with the intent to build a better assembly for connecting population at the global genome level and deeper analysis transcriptomes that further improve our understanding additional outside funding for this or related projects structural variation we find with the underlying nucleotide has to be done. We have decided to emphasize on the of the sunflower domestication and genome diversity for in the future, and if yes, from where? sequence. In total with the previous sequencing we had understanding of these 2 complex genomes. The feasibility crop improvement. performed, we now have over 2.14 billion individual reads to add long read sequences to obtain high quality genome Visit to Paris by Cody Carr (3 weeks): $2000 from a single 10x Genomics Chromium library, which will be evaluate by our 2 laboratories. 5) Give a final accounting of how the France-Berkeley Cyclic Voltammetry International School Participation by amounts to ~59x coverage of the genome after correcting An additional aim of our initial proposal was to Fund award was spent. Do you envision soliciting PI Berben: $4000 for duplicate reads. Graduate student Peter Stokes de analyze optical maps constructed from pools of DNAs additional outside funding for this or related projects Research visit to Paris by PI Berben (3 weeks): $3000 novo assembled this using the SUPERNOVA pipeline, and extracted from groups of landrace or wild samples in in the future, and if yes, from where? Research visit to UC Davis by PI Robert (1 week): $1000 this process yielded an assembly of ~78K scaffolds >10kb order to obtain consensus optical map. Because our initial Supplies and Expenses: $1280 long where >50% scaffolds were >58kb long. Although results with single sample optical maps indicated that The Blackman Lab at UCB spent $2615 for additional TOTAL: $11,280 much improved relative to our previous assembly with less we needed to investigate the data produced revealed sequencing of the 10x Genomics Chromium library for the Supporting Funding: PI Robert trip to UC Davis was also data, most of the scaffolds were too short to be aligned greater divergence among the reference and samples than wild sunflower de novo genome assembly. The CNRGV supported by PI Robert (airfare, $1000); and by UC Davis well with the optical map data. Thus, we have primarily anticipated and because we needed to generate more spent $8,685 for the 2 optical maps from the landrace and Department of Chemistry seminar funds: $450 pursued alignment of the 2 optical maps we produced to genomic sequence for a better wild de novo genome the wild type population. Equipment and supplies provided by Air Liquide (grant the sunflower reference genome. assembly, we made the choice to focus our efforts and to PI Robert) and U.S. Department of Energy (grant to PI Comparing the two optical maps to the sunflower expenditures on those goals instead. Berben). reference genome, we observed that both were larger We are considering options for the pursuit of future than the reference genome (3.1Gb): the landrace and 2) Give the names and ranks of all project funding dependent on the outcome of ongoing work. participants. 26 | France-Berkeley Fund Annual Report 2019-20 Annual Report 2019-20 France-Berkeley Fund | 27 FINAL REPORTS FINAL REPORTS 2018-19 2018-19

Project #9-2018 conference brochure with participant list is provided in associate professor, etc.) of all participants in the the Appendix to the report, in addition to photographs 4) Comment on the collaborative nature of this proj- project. UC PI: Jennifer Bussell (Political Science, UC Berkeley) from the Conference). All of the presentations touched ect, highlighting aspects that have fostered continu- FRANCE PI: Christophe Jaffrelot (Sciences Po, Paris) on topics related to our shared research agenda, and the ing relationships between French institutions and UC Rika Ohkubo, graduate student, UC Berkeley PROJECT TITLE: Political Representation in India: The conference succeeded in bringing together scholars at the campuses. Will future collaboration occur as a result Matthew Eldridge, postdoc, Pasteur Institute Berkeley-Sciences Po Indian Legislators Project cutting edge of research on politics and representation in of this project? MONTH/YEAR OF AWARD ACTIVATION: 2018 India. As originally proposed, the additional costs for this 3) List all publications resulting from this project. workshop were paid for by a combination of the France The FBF grant enabled a very collaborative project, Include journal titles and issues/dates. 1) Describe the work accomplished, in relation to the Berkeley Fund and contributions from the Center on the particularly with regard to our ability to bring together a original project description. Politics of Development (CPD) at Berkeley. Specifically, group of similarly interested scholars for a conference. N/A the France Berkeley Fund covered the international travel We expect that further collaborations will be perceived as In our original proposal, the PIs—Jennifer Bussell, Thad costs of the PIs, while the CPD covered the international more feasible, given our positive experience on this grant 4) Comment on the collaborative nature of this Dunning, and Christophe Jaffrelot—applied for $14,500 to travel costs of all additional participants from outside of and the ease with which we were able to work together project, highlighting aspects that have fostered cover the costs of three workshops to support our shared India and domestic travel costs for those based in India. across institutions. continuing relationships between French institutions research agenda. We received a grant of $11,300 from the The total travel costs for the conference were $23,862, of and UC campuses. Will future collaboration occur as a France Berkeley fund for this initiative. On October 16-17, which the France Berkeley Fund covered $6,797 and CPD 5) Give a final accounting of how the France-Berke- result of this project? 2018, Christophe Jaffrelot, along with our collaborator covered $17,065. ley Fund award was spent. Do you envision soliciting Gilles Vernier, visited UC Berkeley to give a talk at the In Fall 2019, Bussell completed a merging of data additional outside funding for this or related projects It brings together researchers from two leading research Institute for South Asian Studies and to meet with Jen- from Bussell’s Politician Field Experiment dataset and the in the future, and if yes, from where? institutions in the world, UC Berkeley and Pasteur Institute nifer Bussell and Thad Dunning to discuss the next steps Trivedi Center’s Indian Assembly Legislators and Can- and facilitate the translation of novel biological pathways for our co-authored paper on political representation in didates Caste Dataset 1952 – Today, for the purpose of The accounting details are provided above in the response discovered at UC Berkeley into the implications for infec- India. During this workshop, we reviewed the status of the conducting analyses related to a possible working paper. to Question 1. In terms of further requests, we anticipate tious diseases at Pasteur Institute. This interaction enhanc- datasets that we were planning to merge to serve as the These proposed analyses were pre-registered with the that additional work can be conducted remotely and will es the research on infectious diseases at UC Berkeley and basis for the paper and discussed potential approaches for Evidence for Governance and Politics (EGAP) group. The not require additional funding. in return strengths cell biology at Institut Pasteur. We look the framing of the paper. We finished the workshop with a merging of the datasets involved a coding of the jatis forward to future interactions and collaborative opportu- set of next steps for each of the team members, to move (sub-castes) of fictitious individuals in the Bussell dataset nities as a result. forward on the project. by Jaffrelot and our colleague Jusmeet Singh Sihra. Bussell While this workshop was proposed as a part of our appli- then worked with a graduate student at the Goldman 5) Give a final accounting of how the France-Berke- cation, it was funded instead by a grant from the Institute School of Public Policy at Berkeley, Sarang Chaudhary, to Project #10-2018 ley Fund award was spent. Do you envision soliciting for South Asian Studies. This additional $4,000 grant crosscheck the name/jati matches in the dataset. These additional outside funding for this or related projects allowed us to make up for the difference in our proposed data have now been merged and the next step is to clean UC PI: Danica Chen (Nutritional Sciences and Toxicolo- in the future, and if yes, from where? costs for three meetings during the grant period and the and match the jati data, so as to finalize the dataset. gy, UC Berkeley) amount we were awarded by the France Berkeley Fund. Bussell and Dunning subsequently completed the pre-reg- FRANCE PI: Mélanie Hamon (Unité des Interactions Bac- The fund was used to support the UC Berkeley PI to visit On November 8, 2018, Jennifer Bussell and Thad istered analyses and Bussell presented the results as a part teries-Cellules, Institut Pasteur) Pasteur Institute to disseminate knowledge, to support Dunning met with Christophe Jaffrelot in Paris, France of presentations at Yale University in November 2019 and PROJECT TITLE: Effects of aging on the immune system the Pasteur Institute PI to visit UC Berkeley to disseminate for a second meeting to review interim progress on the Columbia University in February 2020. and risk of infectious diseases knowledge, to support a UC Berkeley graduate student dataset and make plans for a third workshop/conference MONTH/YEAR OF AWARD ACTIVATION: December 2018 and a postdoc at Pasteur Institute to work on hemato- in India with a larger set of participants. At this meet- 2) Give the names and ranks of all project participants. poietic stem cells and infection, and to purchase research ing we finalized the list of invitees and made additional 1) Describe the work accomplished, in relation to the supplies for the work. preparations for the conference. The costs associated Christophe Jaffrelot, Professor, CERI, Sciences Po original project description. with this meeting were $3,128. On December 21, 2018, we Thad Dunning, Professor, Political Science, UC Berkeley Project #13-2018 held a conference on Political Representation in India at Jennifer Bussell, Associate Professor, Political Science, UC We have uncovered SIRT2 as a key molecular regulator Ashoka University in Sonepat, India. This conference was Berkeley of hematopoietic stem cell aging. We found that SIRT2 Gilles Vernier, Assistant Professor, Ashoka University UC PI: Todd Dawson (Integrative Biology, UC Berkeley) co-sponsored by our collaborator Gilles Vernier and the is specifically required in aged but not young animals to FRANCE PI: Sylvain Delzon (Université Bordeaux) Trivedi Center for Political Data at Ashoka. Specifically, the Jusmeet Singh Sihra, Graduate Student, Sciences Po prevent the deterioration of hematopoietic stem cells. We Sarang Chaudhary, Graduate Student, GSPP, UC Berkeley PROJECT TITLE: Reconciling critical controversies in Trivedi Center covered the costs of the venue, meals, local have also found that pathogens employ the hosts’ cellular Plant Hydraulics transportation, and housing for conference participants. machinery, including SIRT2, to multiply in the hosts. Using MONTH/YEAR OF AWARD ACTIVATION: 2018 The conference included panels on representation, polit- 3) List all publications resulting from this project. bone marrow transplantation technology, we have gen- Include journal titles and issues/dates. ical economy, and fieldwork in India, with presentations erated a mouse model that activates SIRT2 to rejuvenate 1) Describe the work accomplished, in relation to the from 13 scholars, including Jennifer Bussell and Christophe aged hematopoietic stem cells. original project description. Jaffrelot. Individuals representing universities in Canada, We are continuing to work on these analyses to develop France, India, Israel, and the United States participated (a a working paper that can be subsequently submitted to a 2) Give the names and ranks (ex. doctoral student, journal. Our project proposed to develop a novel collaboration 28 | France-Berkeley Fund Annual Report 2019-20 Annual Report 2019-20 France-Berkeley Fund | 29 FINAL REPORTS FINAL REPORTS 2018-19 2018-19

between the Dawson Lab (UC Berkeley) and the Delzon 3) List all publications resulting from this project. additional outside funding for this or related projects positions. They also confirmed prior findings in rats that Lab (University of Bordeaux) to reconcile the ongoing Include journal titles and issues/dates. in the future, and if yes, from where? neurons are tuned to neighboring whiskers in opposite debate about how vulnerable plants are to xylem phases in the preferred stimulus space. Importantly, this embolism and to exchange ideas and skills specific to Skelton, Anderegg & Lamarque. (2019) Examining variation Currently we have spent $4521 in our travel budget for study yielded a novel framework to understand multi- the field of plant hydraulics. Thus far we have had three in hydraulic and resource acquisition traits along climatic the three visits enumerated above, and intend to spend whisker tuning in S1 that explains the relationship between international exchange meetings: In the spring of 2019, gradients tests our understanding of plant form and the remaining amount in fall of 2020 on final collaborative prior results obtained separately in the two laboratories. Dr. Sylvain Delzon (University of Bordeaux) visited UC function. New Phytologist. 223: 505-507 visits, pending the lifting of travel restrictions. We have This study is under review (Harrell et al., submitted 2019). Berkeley for a two week meeting in Berkeley and Dr. https://doi.org/10.1111/nph.15893 also leveraged the FBF project to secure an additionnal In ongoing experiments, the Shulz lab is examining coding Robert Skelton (UC Berkeley) visited the University of travel grant from the Thomas Jefferson Fund (which differences across cortical layers and fast-spiking vs. Bordeaux for a three week meeting. Then in the fall of Skelton, Dawson, Papper, Kling, Anderegg, Diaz, Lamarque, partially covered the visit of Dr. Anderegg to Bordeaux regular-spiking cell types. 2019, Dr. Leander Anderegg visited the University of Delzon, Ackerly (in submission) Biogeography and and will fund a mini-symposium on oak physiology when The Feldman lab finished one major study on Bordeaux for a three week meeting. These meetings physiology align to support evidence of high xylem travel restrictions ease). This follow up grant proposal multi-whisker tuning in S1, focusing on the subspace of allowed us to exchange ideas and make laboratory capacity to withstand embolism in North American oaks to the Thomas Jefferson Fund also received special 2-whisker combinations and sequences. This revealed measurements at Berkeley, Bordeaux and at the Soleil in review at Proceedings of the National Academy of commendation from the Make the World Great Again that an unexpectedly large fraction of S1 units synthesize Synchrotron, comparing methods developed in the Sciences, USA. initiative. spatiotemporally precise tuning for local motion vectors different labs and learning new techniques. As a result of between neighboring whiskers on the face. This was this collaboration, the junior scientists on the team wrote 4) Comment on the collaborative nature of this published as Laboy-Juarez et al., Nat. Neurosci. 2019. In a synthesis manuscript (Skelton, Anderegg & Lamarque, project, highlighting aspects that have fostered addition, the lab has begun experiments to characterize 2019). continuing relationships between French institutions Project #17-2018 multi-whisker tuning in somatosensory thalamus. The In terms of the technical aims of the project, we and UC campuses. Will future collaboration occur as a design of this experiment was strongly influenced by our have successfully achieved our first aim of using various result of this project? UC PI: Daniel Feldman (Molecular & Cell Biology, UC collaboration discussions, which suggest two different techniques to construct xylem vulnerability curves of Berkeley) streams of multi-whisker input in primary and secondary plants to determine whether newer methods consistently This project has sparked a legacy of collaboration that FRANCE PI: Daniel Shulz (Unité De Neurosciences thalamic relay nuclei for touch. These experiments are yield higher resistance vulnerability curves than traditional extends beyond the scope of the proposal and will Information Et Complexité, CNRS, Gif-sur-Yvette) ongoing. methods. We have obtained curves for sixteen oak species, continue after the end date of the grant. For instance, PROJECT TITLE: Multiwhisker Feature Coding in Mouse and ecologically important genus whose hydraulics are still the collaboration started by this project has already Somatosensory Cortex 2) Give the names and ranks (ex. doctoral student, strongly debated. We have shown that oaks are universally resulted in an additional successful grant proposal to MONTH/YEAR OF AWARD ACTIVATION: October 2018 associate professor, etc.) of all participants in the resistant to embolism, a result that is consistent with the the Thomas Jefferson Fund for future collaborations project. biogeography of various oak species and other elements between the Dawson and Delzon labs about additional 1) Describe the work accomplished, in relation to the of oak physiology. Thus, we have strong evidence that outstanding questions in plant hydraulics. Moreover, the original project description. Shulz laboratory: newer techniques that yield more drought resistant three collaborative visits to date (Dr. Skelton to Bordeaux Daniel Shulz, Director of the Unit of Neurosciences, measurements of xylem vulnerability are physiologically and Dr. Delzon to Berkeley) have revealed unexpected This was a collaborative research project studying Information and Complexity (UNIC) accurate and can resolve the ‘weak vs. strong’ xylem additional areas of overlap between the two labs on the neurobiology of tactile perception by the Shulz Matias Goldin, Postdoctoral researcher debate that plagues the plant hydraulics literature. This the topic of local plant adaptation and its implications and Feldman labs. FBF funding was used to support Evan Harrell, Postdoctoral researcher manuscript is currently under review at the Proceedings for plant responses to climate change. For instance, personnel visits between the two laboratories, with the of the National Academy of Sciences, USA (PNAS). We the collaboration sparked ongoing work exploring goal of discussing research, sharing techniques, and Feldman laboratory: intended two additional site visits to collaboratively the vertical profile of xylem vulnerability in Sequoia developing new lines of research focused on the theme Daniel Feldman, Professor of Neurobiology analyze additional data collected during the previous visits sempervirens (coast redwood, tallest tree on Earth), of multiwhisker sensory coding in mouse somatosensory Keven Laboy-Juarez, PhD student (now graduated) (one to Berkeley in March and one to Bordeaux in April), thanks to serendipitous overlap between ongoing work cortex. We planned four visits, but because of personnel Lucia Rodriguez, PhD student but have had to postpone this exchange due to COVID-19 on conifer xylem in the Delzon lab and existing tree- and schedule constraints only two visits occurred – one and associated travel restrictions. climbing rigs in tall redwoods by Dawson lab. Additionally, by Dr. Matias Goldin, a postdoc in the Shulz laboratory, this collaboration trained junior scientists Skelton and to visit the Feldman lab for a week; and a second by Dr. 3) List all publications resulting from this project. 2) Give the names and ranks of all project participants. Anderegg in new hydraulic methods (the ‘cavitron’ Feldman, to visit the Shulz laboratory for a week. Include journal titles and issues/dates. perfected by the Delzon lab) that they plan to employ as This collaboration resulted in several experiments. • Dr. Sylvain Delzon (Senior Researcher in Forest they set up their own labs (in South African Ecological The Shulz laboratory characterized the whisker movement Harrell et al. 2019 Nature Communications, under review. Ecology, Bordeaux) Observatory Network in fall 2020 and at UC Santa Barbara features that are encoded in the primary somatosensory • Dr. Laurent Lamarque (Postdoctoral Fellow, Bordeaux) in summer 2021). Finally, in addition to travel deferred to (S1) cortex using multi-electrode single unit recordings, Laboy-Juárez KJ, Langberg T, Ahn S, Feldman DE. • Regis Burlett (doctoral student, Bordeaux) COVID, further collaboration is already planned between with a reverse correlation approach that sampled tuning Elementary motion sequence detectors in whisker • Dr. Todd Dawson (Professor, Berkeley) the two labs at a shared session at the MEDICOS scientific in several novel stimulus spaces (Gaussian white noise somatosensory cortex. Nat Neurosci. 2019 Sep;22(9):1438- • Dr. Robert Skelton (Postdoctoral Fellow, Berkeley) conference (September 2020, probably now virtual). in velocity, VELW, and in acceleration, ACCW). They 1449. doi: 10.1038/s41593-019-0448-6. • Dr. Leander Anderegg (Postdoctoral Fellow, Berkeley) discovered novel tuning for combinations of whisker • Jessica Diaz (postbach research technician) 5) Give a final accounting of how the France-Berkeley kinetics and set-point positions, and confirmed this result 4) Comment on the collaborative nature of this Fund award was spent. Do you envision soliciting by applying identical deflections from different starting project, highlighting aspects that have fostered 30 | France-Berkeley Fund Annual Report 2019-20 Annual Report 2019-20 France-Berkeley Fund | 31 FINAL REPORTS FINAL REPORTS 2018-19 2018-19

continuing relationships between French institutions 1) Describe the work accomplished, in relation to the 3) Methane-derived carbon flows through complex from the Joint Genome Institute Community Sequencing and UC campuses. Will future collaboration occur as a original project description. host-virus trophic networks (to be submitted to Nature Program which provided sequence data for all four result of this project? Microbiology) manuscripts (see Section 3). As described in section 4, we The primary objective of this collaboration was to 4) Diversity and composition of host-specific lytic virus have obtained a Department of Energy grant continuing The France-Berkeley Fund funding functioned as seed target and identify viruses associated with specific vary across ecological gradients in soil (to be submitted to the research of this funding, enabling us to launch a fruitful collaboration bacteria and archaea using the bioinformatic analytical FEMS Microbiology Ecology) FBF project. between the Berkeley and CNRS laboratories. We approaches developed at Berkeley in conjunction with undertook the first round of discussions and experiment the experimental systems in use at École Centrale de planning under the FBF funding. Because systems Lyon. This was to be performed in two work packages 4) Comment on the collaborative nature of this neuroscience experiments typically require several years (WP). In WP1, we aimed to used stable-isotope probing to project, highlighting aspects that have fostered Project #23-2018 to complete, it will take time to finish these studies. We link individual hosts (growing nitrifier populations) with continuing relationships between French institutions have enjoyed the collaboration so far, and it is likely to specific viruses by following the transfer of enriched stable and UC campuses. Will future collaboration occur as a UC PI: Teresa Head-Gordon (Departments of extend for several years. isotopes of carbon. In WP2, we aimed to examine how result of this project? Chemistry, Bioengineering, and Chemical and virus community composition varied across an ecological Biomolecular Engineering, Pitzer Center for 5) Give a final accounting of how the France-Berkeley gradient (changing soil pH) to test the hypothesis that The FBF-funded program facilitated two-way exchange Theoretical Chemistry, UC Berkeley) Fund award was spent. Do you envision soliciting despite a potentially broad host range, viral community of technical expertise, with knowledge of virus cultivation FRANCE PI: Jean-Philippe Piquemal (Laboratoire de additional outside funding for this or related projects structures vary in accordance with their prokaryotic host and metagenomics being transferred to the groups of Chimie Théorique, Sorbonne Université, Institut in the future, and if yes, from where? community structures. Berkeley and Lyon, respectively. G. Nicol and M. Firestone Universitaire de France) We were able to successfully perform both have used the FBF-funded research to successfully PROJECT TITLE: Advanced Potential Energy Surfaces for We only spent $6,914.86 of the $11,300 approved budget, WPs as described in the original proposal, with one contribute to applications for performing further Condensed Phase Simulations: Theory and Applica- which funded two collaboration visits. The first visit manuscript being written for each (see Section 3 of this research into host-virus interactions influencing nitrogen tions was by Dr. Matias Goldin from the Shulz laboratory, to report - manuscripts 1 and 2,). In addition, we were able cycling in soil. Specifically, the Department of Energy’s MONTH/YEAR OF AWARD ACTIVATION: November 2018 visit the Feldman laboratory at Berkeley in November to perform two additional WPs. In WP3, we used the Genomic Science Program awarded a consortium grant 2018. This was an 8-day stay that involved presentation same experimental system as WP1 to look at the role of (PI: M. Firestone, international collaborator: G. Nicol) to 1) Describe the work accomplished, in relation to the and discussion of ongoing research, learning recording viruses in influencing microbial communities associated examine ‘Cross Kingdom Interactions in Grassland Soils’ original project description. methods and neurophysiology and data analysis with methane gas fluxes in soil. In WP4, we examined how to quantify the importance of key interactions including techniques, and multiple discussions on aligning research the viruses that infect culturable host bacterial strains predation, competition, and cooperation as controllers Les logiciels de simulation moléculaire font partie in- findings and discussing potential experiments. The second change from soils sampled across an ecological gradient. of mineralization/immobilization, nitrification and N and C tégrante de la chimie et la biologiechimique et ont été visit was by Dr. Feldman to the Shulz laboratory at Gif-sur- Both these additional WPs will produce two further transfer. largement adoptés par les chercheurs universitaires et les Yvette. This was a 6-day visit, that involved presentation manuscripts (see Section 3 - manuscripts 3 and 4). scientifiques de l’industrie. Les prochaines générations de and discussion of research, intensive review of ongoing 5) Give a final accounting of how the France-Berkeley percées scientifiques qui utiliseront des logiciels de chimie studies in the two labs, and advising on the Harrell et al. 2) Give the names and ranks (ex. doctoral student, Fund award was spent. Do you envision soliciting seront rendues possibles par le déploiement de modèles study, which was nearing submission at that point in time. associate professor, etc.) of all participants in the additional outside funding for this or related projects théoriques de pointe et d’algorithmes qui seront sont The remaining funds will be returned to the project. in the future, and if yes, from where? traduits dans un cadre logiciel durable et donc, rapide- France-Berkeley Fund. They were not spent because the ment implémentés sur des plates-formes informatiques other 2 collaboration visits did not happen. We may apply Mia Sungeun Lee – doctoral student Three of the four 1-month exchange visits took place, with haute-performance. À l’heure actuelle, le domaine de la for additional funding for this collaboration, potentially Alexa Nicolas - doctoral student A. Nicolas performing research in Lyon (April 2019) and modélisation et de la simulation moléculaire s’appuie sur within a larger NIH grant. This remains to be determined. Graeme Nicol – professor G. Nicol and M. S. Lee performing research at UC Berkeley une simple représentation de la surface d’énergie po- Mary Firestone - professor (Aug.-Sept. 2019). Unfortunately, $10,657.67 of the original tentielle des molécules et est basée sur ce qu’on appelle budget of $11,400 was spent on these three exchanges les champs de forces « additifs par paires ». Cependant, 3) List all publications resulting from this project. with the Berkeley visits being more expensive than les échecs des modèles additifs se sont, sans ambiguïté, Include journal titles and issues/dates. estimated and M. Firestone therefore did not visit Lyon. accumulés alors que de nouveaux champs de forces, Project #19-2018 Nevertheless, we plus précis, sont développés2 introduisant de nouveaux There are no manuscripts published as of yet, but we have will have further opportunities for bi-lateral research termes à n-corps tels que la polarisation ou des effets non classiques tels que le transfert de charge ou la pénétra- UC PI: Mary Firestone (Environmental Science, Policy & four manuscripts in preparation that will be submitted exchanges as a result of our recently funded DoE in 2020 to high impact general science or top subject- project. tion électrostatique. La plus grande complexité de cette Management, UC Berkeley) physique supplémentaire pose des grands défis pour la FRANCE PI: Graeme Nicol (Laboratoire Ampère, Univ. specific journals. All experimental analyses are complete and analyzed, and all four project participants (see Section A. Nicolas visit to Lyon: $3,448.58 conception rationnelle de champ de forces ainsi que pour de Lyon) la mise au point de nouveaux algorithmes et logiciels et PROJECT TITLE: Determining the interaction of viruses 2 above) will be co-authors on all four publications: G. Nicol visit to Berkeley: $6,709.09 1) Metagenomic analysis of nitrifier-associated viruses in M. S. Lee visit to Berkeley: $500 inhibe leur application aux grands challenges posés par with autotrophic prokaryotic hosts in soil leur application en chimie. MONTH/YEAR OF AWARD ACTIVATION: December 2018 soil (to be submitted to The ISME Journal) Total: $10,657.67 2) Soil pH is a major driver of virome community structure Nous nous proposons d’adresser ces défis à l’aide (to be submitted to Soil Biology and Biochemistry) Additional external competitive funding was obtained du présent projet déposé conjointement par le Prof. 32 | France-Berkeley Fund Annual Report 2019-20 Annual Report 2019-20 France-Berkeley Fund | 33 FINAL REPORTS FINAL REPORTS 2018-19 2018-19

Jean-Philip Piquemal (Sorbonne Université, chimie & Insti- développement de logiciels et des applications chimiques Project #24-2018 tut Universitaire de France) et le Prof. Teresa Head-Gor- ou biochimiques. Les Prof. Piquemal et Prof. Head-Gordon don (University of California, Berkeley) et traitant du planifient un échange de jeunes chercheurs : Dr. Louis UC PI: Rebecca Heald (Molecular & Cell Biology, UC développement et du déploiement de nouvelles méthod- Lagardère (Sorbonne Université) et Dr. Valerie Vaissier Berkeley) 2) Give the names and ranks of all project participants. ologies informatiques dédiées au traitement des surfaces (UC Berkeley). Ces jeunes chercheurs travailleront FRANCE PI: Denis Chrétien (Université de Rennes 1) d’énergie potentielle avancées. La recherche proposée ensemble pour implémenter des approches du type iEL/0- PROJECT TITLE: Understanding the structural basis Rebecca HEALD, UC Berkeley Professor repose sur trois axes. Tout d’abord, afin d’améliorer SCF, de multitimestepping et de QM/MM dans Tinker- regulating the size and architecture of mitotic spindle Denis CHRETIEN, CNRS Research Director l’efficacité des champs de force polarisables, nous nous HP. Sous la direction de l’Université de Berkeley, nous MONTH/YEAR OF AWARD ACTIVATION: December 2018 Romain GIBEAUX, CNRS Researcher proposons de commencer par implémenter l’approche effectuerons de nouveaux calculs de champ électrique sur Maiko KITAOKA, UC Berkeley PhD Student l’iEL/0-SCF élaborée dans le groupe de Teresa Head-Gor- les sites actifs d’enzymes pour éprouver la méthodologie 1) Describe the work accomplished, in relation to the Karel MOCAER, University of Rennes 1 Master Student don qui élimine les itérations SCF habituelles des champs et mesurer les gains enzymatiques sur les mutations original project description. de forces polarisables à faire appel de manière plus expérimentales 3) List all publications resulting from this project. extensive aux méthodes à pas multiples « multi-timesteps The goal of this project was to provide a better under- Include journal titles and issues/dates. » , qu’aussi bien en ce qu’en intégrant des calculs avancés 3) List all publications resulting from this project. standing of spindle size and architecture by examining polarisables dans des méthodes hybrides QM/MM6. Deux- Include journal titles and issues/dates. microtubule subpopulations at the single-microtubule While we still need to perform some Expansion ièmement, ces améliorations algorithmiques doivent être N/a level and comparing them between X. laevis and X. tropi- Microscopy experiments, we expect to submit a paper implémentées dans un logiciel robuste. Pour cela, nous calis. For this, we explored two separate microtubule-orga- about the application of this method to the study of avons l’intention de faire appel au programme Tinker-HP9 4) Comment on the collaborative nature of this nizing sites integral to spindle assembly: the spindle poles structures assembled in Xenopus egg extract in the next mis au point par le groupe de J.P. Piquemal. Enfin, le cou- project, highlighting aspects that have fostered (Aim 1) and chromatin (Aim 2). During the six first months few months. In addition, various biological results obtained plage de ces nouveaux algorithmes et d’un logiciel continuing relationships between French institutions of the FBF project, we focused on resolving microtubule during the course of this FBF project are likely to be efficace vas nous permettre d’effectuer des calculs de and UC campuses. Will future collaboration occur as a organization at spindle poles (Aim 1). Under the supervi- included in future publications of Romain Gibeaux and champ électrique beaucoup plus sophistiqués au sein de result of this project? sion of Romain Gibeaux in the Chrétien Lab, Karel Mocaer, Maiko Kitaoka, but this is expected to be in the longer- site actifs d’enzymes afin de faire des prédictions quant a master’s student, characterized DMSO asters in both X. term. à l’améliorations des étapes catalytiques d’enzymes Les progrès de la recherche proposée auront un grand laevis and X. tropicalis extracts, including their size, micro- artificielles. impact permettant de pouvoir mieux modéliser des tubule density and distribution. To further analyze aster 4) Comment on the collaborative nature of this Les surfaces d’énergie potentielle classiques ont molécules modèles afin d’aider les chimistes de synthèse organization, we set out to develop Expansion Microscopy project, highlighting aspects that have fostered atteint le seuil d’une transition générationnelle, s’éloignant à concevoir de nouveau médicaments, de nouveaux for Xenopus egg extract microtubule structures and thus continuing relationships between French institutions des modèles à charges ponctuels qui, bien qu’établies matériaux fonctionnels ou de créer de nouveaux gain resolution. To do so, Karel joined the Heald Lab for and UC campuses. Will future collaboration occur as a apparaissent intrinsèquement limités, pour aller vers des catalyseurs qui 3 months and worked under the supervision of Maiko result of this project? modèles plus complexes et coûteux en temps de calcul, accélèreront les réactions chimiques sur plusieurs ordres Kitaoka, PhD Student Together, they started to optimize mais qui permettent une reproduction plus exacte d’un de grandeur. Les Prof. Piquemal et Prof. Head-Gordon the method, and Karel reached a final protocol back in This project led us to collaborative work that have ex- plus large éventail de données de référence avec à la sont deux chercheurs internationalement reconnus qui Rennes. We now have acquired both spindles and asters in ceeded beyond expectations. Not only did we exchange clé une meilleure prédictibilité en terme d’applications. conçoivent des méthodes allants au-delà des champs de both extracts at high-resolution. We validated the meth- students, but we also enabled young scientists to work Cependant la plus grande précision introduite par force additifs pour inclure maintenant les effets à Ncorps od and final experiments will be performed within the synergistically together. Moreover, while the methods ces améliorations des forces à courte portée, de la dans ce que nous appellerons des surfaces d’énergie next 6 months between Rennes and Berkeley to examine we originally planned to apply to this project were rather polarisabilité, du transfert de charge, ou des traitements potentielle avancées. La combinaison des points forts des microtubule organization in greater details and prepare classical and wellestablished, the continuous communica- explicites par mécanique quantique ouvrent plusieurs équipes de deux chercheurs apportera une synergie des a manuscript for publication. For the second half of this tion and feedback on results between our two laboratories défis algorithmiques et logiciels au sein des plates-formes algorithmes et logiciels pour la mise au point de champs FBF project, we focused on Investigating chromatin-driven led us to orient our research towards more original and matérielles présentes ou à venir. Ces défis limitent à leur de forces avancés qui seront mis à la disposition de microtubule organization (Aim 2). To do so, Maiko Kita- innovative methods. By the end of this FBF project, the tour la large adoption par la communauté de chimie chaque grande université de recherche, centres de calcul oka joined the Chrétien lab for four weeks to apply with work of Karel Mocaer, Maiko Kitaoka and Romain Gibeaux computationnelle de telles nouvelles approches. Le et qui seront la R & D dans les industries s’étendant Romain Gibeaux an electron microscopy method, led to the successful application of not only Expansion travail proposé permettra de surmonter ces obstacles des produits pharmaceutiques aux technologies de ChromEMT, to study egg extract chromosomes and asso- Microscopy but also ChromEMT to the egg extract system, par l’intermédiaire de multiples travaux intégrés entre les semiconducteurs. ciated microtubules. While, analyzing single chromosomes which would not have been possible by one of our two deux groupes de recherche et seront largement diffusées appeared too challenging, we were able to successfully ap- laboratories alone. It is clear that these approaches will be à la communauté des chercheurs sous la forme de 5) Give a final accounting of how the France-Berkeley ply ChromEMT to whole X tropicalis spindles. We acquired of great advantage to both of our laboratories and lead to publications et de logiciels. Fund award was spent. Do you envision soliciting a large 3D volume of the metaphase plate (3.4 x 2.8 x 1.5 further collaborative research. In particular, we are already additional outside funding for this or related projects μm) and are currently modeling chromatin and microtu- considering on using the development of ChromEMT for 2) Give the names and ranks (ex. doctoral student, in the future, and if yes, from where? bules with the goal to reveal chromatin details at the levels the egg extract to collaborate on a new chromatin biology associate professor, etc.) of all participants in the of centromeres and bulk chromatin, as well as details project. Finally, an additional aspect is that the stimulating project. Le budget prend en compte ces 3 visites (de 10 jours à about associated microtubules. If promising, we will research done during this FBF project was instrumental in 2 semaines) sur la période 2018-2019. Plus précisément, then use this method to analyze X. laevis spindle chromo- allowing Karel Mocaer to join the PhD programme of the La recherche proposée assure la formation idéale pour nous anticipons un montant de $5500 en frais d’avion et somes for comparison. EMBL, the leading European research laboratory. de jeunes chercheurs en chimie théorique à travers le de $6500 pour les dépenses locales. 34 | France-Berkeley Fund Annual Report 2019-20 Annual Report 2019-20 France-Berkeley Fund | 35 FINAL REPORTS FINAL REPORTS 2018-19 2018-19

5) Give a final accounting of how the France-Berkeley mented by Fournet, Hickey, Amory, and Schram (for these 5) Give a final accounting of how the France-Berke- In preparation of the international workshop Fund award was spent. Do you envision soliciting last two collaborators, see next section). Publication in ley Fund award was spent. Do you envision soliciting in 2019, prof. Kondolf organized a smaller one-day additional outside funding for this or related projects the open-access series California Classical Studies is envi- additional outside funding for this or related projects workshop in Lyon in the fall 2018, with funding from the in the future, and if yes, from where? sioned. in the future, and if yes, from where? RFIEA (the French Network of Institutes for Advanced Study). The Lyon workshop was aimed at kick-starting To continue this project, Romain Gibeaux applied and 2) Give the names and ranks (ex. doctoral student, According to Hickey’s personal records (see below), all of the conversation which is at the core of the project by obtained a HFSP Career Development Award of $300,000. associate professor, etc.) of all participants in the our funds were spent in connection with the London con- focusing on three river basins – the Rhone, the Po, and project. ference (travel, accommodation, refreshments, dinner). the Ebro – on which a larger body of research exists and Unfortunately Hickey’s former MSO did not debit all of which pose relatively smaller methodological issues for an Besides the project coordinators (* = participant in Lon- the expenses properly, and a significant F-BF balance is still interdisciplinary analysis. The workshop convened scholars don conference; # = contributor to final publication): showing in PI Portfolio. Hickey’s current MSO is aware of and practitioners from Italy, France and Spain and allowed Project #25-2018 the problem and is attempting to fix the accounting as of us to identify some issues that will guide the discussion in Yasmine Amory*# (post-doctoral scholar, Ghent; 2018 PhD this writing. Berkeley this spring. UC PI: Todd Hickey (Classics/Bancroft Library UC from EPHE) Following the successful workshop in Lyon we Berkeley) Joshua Benjamins (UCB PhD student, Classics) Hickey’s personal records: issued the call for paper on January 2019 (see attached FRANCE PI: Jean-Luc Fournet (Collège de France/École Christopher Blunda (UCB PhD student, History [has since Travel to London: $2,862.32 poster) and circulated it through relevant networks. As Pratique des Hautes Études, Paris) received doctorate]) Accommodation in London: $3,742.62 discussed in our proposal, the call for paper explicitly PROJECT TITLE: Everyday writing in a literary town: Abigail Hoskins (UCB PhD student, AHMA) Conference refreshments: $1,113.50 encouraged Ph.D. students, postdocs and other early Some rediscovered tablets from late antique Panopolis Julia Lougovaya* (affiliated faculty, Heidelberg) Conference meal: $804.72 career scholars to apply. The call closed on January 31. We MONTH/YEAR OF AWARD ACTIVATION: December 2018 Valérie Schram*# (post-doctoral scholar, Collège de Total: $8,523.16 + airfare for Stubblefield (DirectBill to received 35 applications from scholars working in multiple France) wrong fund by MSO but certainly >$749.84) countries and with a background in environmental history, 1) Describe the work accomplished, in relation to the Samuel Stubblefield* (UCB PhD student, History) Small budget overage paid from Hickey’s research funds. historical geography, Science and technology Studies original project description. Mustafa Yildiz (UCB PhD student, History) and fluvial geomorphology. We selected a pool of 13 Michael Zellmann-Rohrer* (post-doctoral scholar, Oxford; participants, including 2 Ph.D. students and 5 early career The plan of work outlined in our project proposal is being 2016 PhD from UCB) scholars. Together with the 13 applicants selected, we fulfilled, though the pace of our progress has been im- invited 3 other scholars to join the discussion. pacted by the Covid-19 pandemic. The Berkeley and Paris 3) List all publications resulting from this project. Project #30-2018 The workshop was very successful. It was teams began independent research on the Panopolite co- Include journal titles and issues/dates. organized in four subsequent panels, some structured dex of wooden tablets in spring 2019. This initial phase of UC PI: G. Mathias Kondolf (Landscape Architecture & geographically, and others thematically in which the work culminated in a one-day conference and workshop Our monograph (text, commentary, synthetic essays) is in Environmental Planning, UC Berkeley) attendees presented their original research (see attached at the British Library that featured the entire Paris team as progress; see (1) above. It is anticipated that a couple of FRANCE PI: Giacomo Parrinello (Centre d’Histoire de programme). The four panels were followed by group well as Hickey and one of the graduate students from his additional publications will result from the London confer- Sciences Po, Paris) discussions aimed at teasing out common themes and papyrology seminar (for details, please see our interim re- ence. PROJECT TITLE: The Social Life of the Sediment questions, which were in turn discussed in the final general port, which included a copy of the program). The London Balance: A Social and Geomorphic Approach to the debate. In the workshop aftermath, professor Parrinello event also furnished an opportunity to examine the codex 4) Comment on the collaborative nature of this proj- Transformation of River Systems and Deltas and Kondolf discussed publication strategies, identifying itself, which enabled us to reconstruct its form in Antiquity ect, highlighting aspects that have fostered continu- MONTH/YEAR OF AWARD ACTIVATION: September 2018 a core group of participants to invite to contribute to a (i.e., the proper order of its constituent boards). During ing relationships between French institutions and UC special issue and the journal Water History as the best this autopsy, the British Library kindly agreed to our campuses. Will future collaboration occur as a result 1) Describe the work accomplished, in relation to the venue for it. The special issue is currently in the making request for multi-spectral imaging of the object, imaging of this project? original project description. (see below). that has since revealed several “hidden” texts from earlier in the codex’s life. As noted in the interim report, our teams have brought The project focuses on the nexus of social and natural 2) Give the names and ranks of all project participants. In the wake of the London meeting, we decided their own approaches and emphases to the material, and processes behind the modification of sediment balance to hold a second, more intensive (text-focused) workshop these are wonderfully complementary. Our final publica- in river systems and deltas. It does so by combining G Mathias Kondolf, full professor, Sciences Po, France in Berkeley on 6-7 April 2020. This event unfortunately tion will be something that none of us could have pre- methodologies and approaches from the social sciences Giacomo Parrinello, assistant professor, Sciences Po, had to be cancelled because of the pandemic (new dates pared on his or her own. and humanities and the natural sciences, namely fluvial France TBD), as did Hickey’s trip to the British Museum (sched- Hickey and Fournet have known each other for geomorphology. It builds on a pre-existing collaboration Joana Guerrin, assistant professor, University of Nimes, uled for the week of 22 March 2020; rescheduled for over twenty years, but this was their first opportunity to between the two coordinators, a fluvial geomorphologist France December 2020) to complete research into the codex’s collaborate. The project has deepened their working rela- (prof. Kondolf) and an environmental historian (prof. Simone Bizzi, assistant professor, University of Padua, Italy provenance. The team’s preliminary work on the codex tionship and also enhanced or established relationships for Parrinello) and was originally aimed at organizing an Nicola Surian, full professor, University of Padua, Italy did feature in Hickey’s presentation at the 29 Congresso all who have participated in it. We are certain that these international, multidisciplinary workshop in Berkeley in Ramon Batalla, full professor, University of Leida, Spain Internazionale di Papirologia in Lecce (29 July 2019). As connections will bear fruit in other contexts in the years the spring 2019. The workshop, as in the original proposal, Damia Vericat, associate professor, University of Lleida, of 7 May 2020, a 39-page (ca. 19,000 word) manuscript ahead. was held on May 29-30, during prof. Parrinello’s visit in Spain. edition of the codex exists. This is currently being aug- Berkeley. Faisal Husain, assistant professor, Penn State University, 36 | France-Berkeley Fund Annual Report 2019-20 Annual Report 2019-20 France-Berkeley Fund | 37 FINAL REPORTS FINAL REPORTS 2018-19 2018-19

USA The project is the outcome of an ongoing collaboration MONTH/YEAR OF AWARD ACTIVATION: November 2018 daily basis with Pr. Limmer and his PhD student C. Gao. Dale Stahl, assistant professor, University of Colorado between Prof. Kondolf of UC Berkeley and Prof. Parrinello The next milestone was the joint visits of Pr. Denver, USA of Sciences Po (Paris) on the social dimension of sediment 1) Describe the work accomplished, in relation to the Rotenberg (with FBF support) and Pr. Salanne (with Celine Pierdet, assistant professor, Universite de fluxes alteration in river systems. Every step of the project, original project description. another funding source) to Berkeley in July, during which Technologie Compiègne, France from drafting the proposal to drafting the call for paper, we started to write a publication on the non-equilibrium Chris Hackney, postdoctoral researcher, University of Hull, from evaluating the abstracts to selecting and inviting Once we received the notification of the award, we have sampling of trajectories. This new method allowed us to UK the participants has been done jointly by the two PIs. The agreed to postpone its activation until November, 2018. determine the non-linear response of bulk electrolytes to Rafa Schmitt, postdoctoral researcher, Stanford University, collaboration between Kondolf and Parrinello has already This allowed us to better plan our joint work program an applied electric field. The corresponding publication USA led prof. Kondolf to visiting Sciences Po in the spring and mutual visits supported by the FBF in 2019. However, (Section 3) was finalized in the following months and first Susan Lawrence, full professor, La Trobe University, 2018, in which occasion he intervened in prof. Parrinello’s the collaboration started remotely in 2018 via regular submitted in October. Australia seminar in environmental history and led a field trip. Skype meetings and a visit of a PhD student from the During this visit to Berkeley, we also made James Grove, full professor, University of Melbourne, The France-Berkeley Fund project developed French group, Zhujie Li, in Berkeley in February 2018 (with progress on the use of advanced Statistical Mechanical Australia these exchanges further: the workshop in Berkeley has a different funding source). These exchanges allowed methods to investigate electrochemical interfaces. Carrie Monahan, science director, The Sierra Fund (TSF) been the cornerstone moment of prof. Parrinello’s visit to progress on the first aspect of the project, namely the Analytical calculations during this visit and the numerical Ashley Carse, associate professor, Vanderbilt University Berkeley in May 2019. The workshop, moreover, integrated molecular simulation of “water-in-salts” electrolytes near simulations performed in Paris by L. Scalfi during the Joshua Lewis , research assistant professor, Tulane two other scholars coming from French institutions, the graphite electrodes, in the framework of Z. Li’s PhD (now following months resulted in another article, which was University, USA University of Nimes and Université de Technologie de finished) supervised by Mathieu Salanne. submitted in November and is already accepted for Ramya Swayamprakash, doctoral student, Michigan State Compiègne, who came to Berkeley on May 29-30, 2019. The first visit funded by the FBF took place in publication in Physical Chemistry Chemical Physics (see University, USA The larger collaborations which are part of the project, March 2019, when David Limmer visited Paris. Discussions Section 3). Alejandro Camargo, assistant professor, Universidad del which were consolidated in the preparatory workshop in on this first topic during his visit were also beneficial for A last exchange was planned, with a visit of C. Norte - Barranquilla, Colombia Lyon in the fall 2018, also including scholars from the Ecole the PhD project of Nidhal Ganfoud, related to aqueous Gao in Paris during her stay in the United Kingdom in the Craig Colten , full professor, Lousiana State University, USA Normale Superieure de Lyon. electrolytes at electrochemical interfaces. Furthermore, fall. However such a visit turned out at the last minute to These collaborations will continue for the near a third PhD student, Laura Scalfi (who had done an be impossible for visa reasons, and unfortunately it was 3) List all publications resulting from this project. future within the framework of a new funded project led internship in the Berkeley group in 2018), benchmarked too late for Pr. Limmer to plan a second visit in Paris for Include journal titles and issues/dates. by professor Parrinello and to which professor Kondolf is the code developed in the Paris group for the classical himself during the duration of the FBF grant. Nevertheless, strictly associated, funded by a 4-year grant from the city molecular simulation of constant-potential electrodes the collaboration continued actively with weekly remote The main publication from this project will be the special of Paris and entitled “Shifting Shores: An Environmental (Metalwalls) against the one used in Berkeley (a modified meetings between both groups. In particular, additional issue of the peer-reviewed journal in environmental History of Morphological Changes in Mediterranean version of a generic purpose MD software, Lammps), work is currently being performed to prepare a revised and interdisciplinary water history “Water History”, Deltas”. which uses different periodic boundary conditions for version of the publication on the non-equilibrium sampling edited by Springer, which is currently in the making. electrostatics. of trajectories in bulk electrolytes. The issue, tentatively entitled The Social Life of the 5) Give a final accounting of how the France-Berkeley D. Limmer’s visit in Paris also allowed the start of Sediment Balance, will be published in 2020 and include Fund award was spent. Do you envision soliciting another aspect of the proposal, namely the application of 2) Give the names and ranks of all project participants. an introduction from professor Parrinello and professor additional outside funding for this or related projects the statistical tools developed in the Berkeley group for Kondolf, plus a maximum of 7 articles, pending their in the future, and if yes, from where? the enhanced sampling of relevant trajectories to the case In Berkeley: David Limmer (Prof.), Chloe Gao (PhD successful peer review. Two articles have already been of electric transport in electrolytes. Our collaboration on student) submitted and are currently under review, the others will A final accounting of expenses under the grant is attached. this topic involved a PhD student in Berkeley (Chloe Gao) In Paris: Benjamin Rotenberg (Prof.), Mathieu Salanne be submitted in the coming weeks. There is a balance of $442.06 remaining, which will and a post-doc in Paris (Dominika Lesnicki). The latter (Prof.), Zhujie Li (now Dr), Laura Scalfi (PhD student), In addition, a journal manuscript The Invisibility of be returned to FBF. We have in fact already obtained adapted the tools developed in Berkeley to the case of Dominika Lesnicki (Dr), Nidhal Ganfoud (now Dr) Sediment: a Socio-Geomorphic Perspective On a Great additional outside funding from the City of Paris, as interest for this project. Discussions in Paris also resulted Challenge for Water and Catchment Management is in mentioned above. This project will hopefully lead to in promising directions for a new sampling method, based 3) List all publications resulting from this project. preparation, involving 7 of the workshop participants, further collaboration and funding bids on this exciting on out-of-equilibrium trajectories, which was then further Include journal titles and issues/dates. with expected submission in early February 2020. Prof interdisciplinary topic. investigated in Berkeley. Kondolf presented a paper by this title (co-authored by Since the first aspect of the proposal (molecular L. Scalfi, D.T. Limmer, A. Coretti, S. Bonella, P.A. Madden, Prof Parrinello and Dr Schmitt) to the annual meeting description of electrochemical interfaces) was on M. Salanne, B. Rotenberg, “Charge fluctuations from of the American Geophysical Union in San Francisco in track and could be continued remotely, we have molecular simulations in the constant-potential ensemble”, December 2019. Project #36-2018 decided to focus the remaining efforts on the second To appear in Physical Chemistry Chemical Physics (http:// part (methodological developments for the sampling doi.org/10.1039/C9CP06285H) 4) Comment on the collaborative nature of this UC PI: David Limmer (Chemistry, UC Berkeley) of transport properties), since this was where the project, highlighting aspects that have fostered FRANCE PI: Benjamin Rotenberg (Chimie, Sorbonne collaboration could benefit the most from mutual visits. D. Lesnicki, C.Y. Gao, B. Rotenberg, D.T. Limmer, “Field- continuing relationships between French institutions Université) To that end, it appeared that the most efficient way to dependent conductivities of electrolyte solutions from and UC campuses. Will future collaboration occur as a PROJECT TITLE: Understanding energy storage in highly ensure fast progress in this direction was that the post- generalized fluctuation-dissipation relations”, Submitted result of this project? concentrated aqueous salt mixtures doc working on this aspect in Paris, D. Lesnicki, would visit (https://arxiv.org/abs/1910.10084) the Limmer group in June, where she could interact on a 38 | France-Berkeley Fund Annual Report 2019-20 Annual Report 2019-20 France-Berkeley Fund | 39 FINAL REPORTS FINAL REPORTS 2018-19 2018-19

4) Comment on the collaborative nature of this Project #44-2018 Fund award was spent. Do you envision soliciting close to the hole’s horizon. This provides a clear answer project, highlighting aspects that have fostered additional outside funding for this or related projects to a long-standing question. An article is currently under continuing relationships between French institutions UC PI: Todd Olson (History of Art, UC Berkeley) in the future, and if yes, from where? preparation to be submitted by December (see hereafter). and UC campuses. Will future collaboration occur as a FRANCE PI: Anne Lafont (École des Hautes Études en This work also paves the road to result of this project? Sciences Sociales - Paris) Initial funds for the initial technical advice have been spent. ab-initio modeling of synthetic observables for direct PROJECT TITLE: Tabac/Chatbot: Education and Reserved funds will be spent on travel costs for the French comparison with black hole images by the Event Horizon As put forward in our proposal, this collaboration Interaction in the Museum Exhibition collaborator, exchange of research and implementation of Telescope (EHT) and gamma-ray flares routinely observed involves one PI in Berkeley (Pr. Limmer) and two in Paris MONTH/YEAR OF AWARD ACTIVATION: 2018 the project. Mellon Project Grant funds will be solicited for in the GeV and TeV gamma-ray bands by Fermi and atmo- (Pr. Rotenberg and Pr. Salanne), as well as many young publications related to this project. spheric Cherenkov telescopes. researchers: 4 PhD students (Z. Li, L. Scalfi and to a lesser 1) Describe the work accomplished, in relation to the extent N. Ganfoud in Paris; C. Gao in Berkeley) and 1 post- original project description. 2) Give the names and ranks of all project participants. doc who’s main activity is directly related to this project (D. Lesnicki). These young researchers were actively The project had to adapt to some challenges. In response Project #46-2018 • Benjamin Crinquand, doctoral student, Université involved in the exchanges, including a visit of Dr. Lesnicki to a change in the exhibition venue and the initially Grenoble Alpes. will to Berkeley in June, and despite the fact that C. Gao proposed theme (Tobacco in the eighteenth century), we • Benoît Cerutti, Chargé de Recherche CNRS, Université did not manage to come to Paris in September as planned, UC PI: Eliot Quataert (Astronomy, UC Berkeley) Grenoble Alpes. proposed a modest test space at the Institut d’Histoire FRANCE PI: Benoit Cerutti (Institut de Planétologie et due to administrative issues. de l’Art (IHNA, Paris) in order to use of pictures of • Jordy Davelaar, doctoral student, Radboud University. During his visit in Paris, Pr. Limmer gave a seminar d’Astrophysique de Grenoble) • Guillaume Dubus, Directeur de Recherche CNRS, nineteenth-century novelist Alexandre Dumas from the PROJECT TITLE: Where General Relativity, quantum in the PHENIX laboratory and exchanged with other collection of Prof. Darcy Grimaldo Grigsby (who has Université Grenoble Alpes. colleagues at Sorbonne Université. He also joined Pr. electrodynamics, and plasma physics meet: first- • Kyle Parfrey, Associate research scientist, Princeton agreed to provide content for the chatbot). Prof. Lafont’s principles models of emission from astrophysical Rotenberg for the annual meeting of a European Training expertise will be utilized for providing content. We have University. Network (NANOTRANS, on the transport of soft matter black holes • Alexander Philippov, Associate research scientist, also identified a new independent French software MONTH/YEAR OF AWARD ACTIVATION: 2018 at the nanoscale), where he gave an invited lecture and engineer. Covid-19 has delayed the implementation of the Center for Computational Astrophysics, Flatiron had opportunities to exchange with other European Institute. project. Karine Douplitzky, Ph.D. candidate, UC Berkeley, is 1) Describe the work accomplished, in relation to the colleagues, in particular the other French partners of this currently sheltering in France and advancing the project. • Eliot Quataert, Professor UC Berkeley. network (Lydéric Bocquet, Emmanuel Trizac). original project description. • Bart Ripperda, Postdoctoral fellow, Center for Pr. Rotenberg, who has already visited Berkeley in 2) Give the names and ranks of all project participants. Computational Astrophysics, Flatiron Institute. the past, took the opportunity of his visit in July to engage The fully general relativistic particle-in-cell (GRPIC) code is complete and fully operational. To the best of our in further discussions with other groups, in particular that Karine Douplitzky, Ph.D. candidate 3) List all publications resulting from this project. of Phillip Geissler. He will visit again in January 2020 for knowledge this is the only multi-dimensional code in the Include journal titles and issues/dates. Anne Lafont, Professor world of this type with this capability. We performed the the Berkeley Statistical Mechanics Meeting as an invited Todd P. Olson, Professor speaker, and he will take this opportunity to extend first ab-initio simulations of black hole spin extraction by Parfrey, K., Philippov, A., and Cerutti, B., “First-Principles his stay for a few days to work on the revisions of the magnetic fields in the form of a plasma jet (also known as Plasma Simulations of Black-Hole Jet Launching”, Phys. second article, and to plan the next steps of this fruitful the “Blandford-Znajek” process). To our great surprise, we Rev. Lett. 122, 035101 (2019). 3) List all publications resulting from this project. discovered a significant amount of particles with negative collaboration. Include journal titles and issues/dates. This article was selected by the editorial board as a energy as seen by a distant observer swallowed by the research highlight and made the cover page of the journal. 5) Give a final accounting of how the France-Berkeley black hole which are effectively slowing down the hole and This work has been part of a press release at the LBNL and An exhibition pamphlet will accompany the final powering the jet. This process known as the “Penrose” Fund award was spent. Do you envision soliciting implementation of the project. Research will be shared at CCA. Several scientific magazines have also dedicated a additional outside funding for this or related projects mechanism can only be accurately captured with GRPIC special news article to comment on the significance of this through the Department of History of Art website simulations (or with any kinetic approach). Simulations in the future, and if yes, from where? (forthcoming). work, see APS Viewpoint, Nature, La Recherche. have also clearly identified the role of magnetic reconnec- Crinquand, B., Cerutti, B., Philippov, A., Parfrey, K., and tion as a means to - Visit of Pr. Limmer to Paris in March 2019: $4,245.42 4) Comment on the collaborative nature of this Dubus, G. “Ab-initio multi-dimensional simulations of - Visit of Dr. Lesnicki to Berkeley in June 2019: $1,892.50 accelerate particles to high energies within the innermost ergospheric pair discharges around black holes”, under project, highlighting aspects that have fostered parts of black hole magnetospheres. The second stage of - Visit of Pr. Rotenberg to Berkeley in July 2019: $4004.81 continuing relationships between French institutions preparation to be submitted to Phys. Rev. Lett (2019). Total expenses: $10,142.73 this project has begun in early 2019 with the development and UC campuses. Will future collaboration occur as a of the radiative capabilities of the code (GRRPIC) carried Pr. Salanne (Paris) also visited the Limmer group during result of this project? 4) Comment on the collaborative nature of this Pr. Rotenberg’s stay in Berkeley, with a different funding out by PhD student Benjamin Crinquand in Grenoble. project, highlighting aspects that have fostered source. The code models electron-positron pair creation and continuing relationships between French institutions The changing focus of the project has put some strain on gamma-ray production via inverse-Compton scattering Pr. Rotenberg will visit again in January 2020 with different the relationship. We wish to address this with in person and UC campuses. Will future collaboration occur as a funding sources. using realistic cross sections. These new capabilities are result of this project? collaboration once travel embargos have passed. essential to uncovering how plasma is generated at the base of black hole jets. We discovered that pair creation is 5) Give a final accounting of how the France-Berkeley Our collaboration strongly relied on regular Skype tied to a feature, known as the inner light surface, that lies meetings (about 1 per month) and Slack channel for 40 | France-Berkeley Fund Annual Report 2019-20 Annual Report 2019-20 France-Berkeley Fund | 41 FINAL REPORTS FINAL REPORTS 2018-19 2018-19

rapid and interactive discussions. Technical developments role in this cooling. We have used the model framework This project has been very collaborative leading on the code were shared via a common git repository. 1) Describe the work accomplished, in relation to the to test the hypothesis that global cooling over the past 15 to substantial interactions between researchers at As promised, we have also organized two collaboration original project description. million years has been driven by tectonic emergence of Berkeley and Géosciences Environnement Toulouse. meetings, one on each side of the Atlantic. The first the Southeast Asian islands. We find that the majority of These collaborative relationships will be sustained into collaboration meeting was held in New York City in the In summer 2018, Nicholas Swanson-Hysell and Berkeley cooling over the past 15 million years can be explained by the future. Significantly, the project directly led to Pierre Center for Computational Astrophysics, March 27-30 PhD student Yuem Park traveled to Toulouse to conduct emergence of the Southeast Asian islands. These results Maffre beginning a postdoctoral researcher position at UC 2019. This was the most convenient place to meet for all hands-on research with Yves Goddéris and his PhD were presented by Berkeley PhD student Yuem Park Berkeley following completion of his PhD in Toulouse. This of us (Parfrey, Philippov and Quataert were all based in student Pierre Maffre. During this time, Swanson-Hysell at the American Geophysical Union Annual Meeting in postdoc is supported by a National Science Foundation the area at this time of year). The second collaboration and Park gained hands-on experience working with Yves December, 2019. A manuscript describing these results has grant that was funded to continue trajectories associated meeting just ended last week (November 20-22) and to apply the GEOCLIM modeling framework to begin been prepared for submission to the Proceedings of the with project research. A significant part of the success of was organized in Grenoble. These meetings were to constrain the climatic effects of tropical mountain- National Academy of Sciences. the proposal was that it incorporated preliminary model organized in the form of a working group rather than a building. An exciting trajectory of model development results that arose from project research. Goddéris is a standard workshop with a series of talks. Our goal was to that Goddéris and Maffre had pursued prior to our 2) Give the names and ranks of all project participants. named collaborator on the NSF grant. The Berkeley team brainstorm on technical aspects on the code, the physics visit was to implement dynamic development of rock continues to be regularly communicate with Goddéris as of black hole electrodynamics, and the content of our weathering profiles. In seeking to apply this model to Yves Goddéris, Directeur de recherche (Géosciences we continue to write up project results. papers in progress. It was also an opportunity to invite a the past, we realized that it was important to develop an Environnement Toulouse) few external experts to push the discussion further and in implementation of the numerical modeling framework Pierre Maffre, was PhD in Toulouse; now Postdoctoral 5) Give a final accounting of how the France-Berkeley a broader context. that incorporates differences in geology in addition to Researcher at UC Berkeley Fund award was spent. Do you envision soliciting differences in climate (e.g. precipitation and temperature) Nicholas Swanson-Hysell, Assistant Professor (UC additional outside funding for this or related projects 5) Give a final accounting of how the France-Berkeley and in slope. We were able to implement different rock Berkeley) in the future, and if yes, from where? Fund award was spent. Do you envision soliciting types (lithologies) with different carbon sequestration Yuem Park, PhD Student (UC Berkeley) additional outside funding for this or related projects potentials in the model. The implementation and The France-Berkeley Fund award was spent on the in the future, and if yes, from where? calibration of this model occurred both through remote 3) List all publications resulting from this project. following activities: collaboration and in-person meetings. Goddéris invited Include journal titles and issues/dates. • Travel for PI Swanson-Hysell and PhD student Park The airfares of the French team as well as the per diem Swanson-Hysell to give a talk in a Union session he was to Toulouse in summer 2018 to initiate project research were covered by the grant (about $2000). A significant co-convening at the European Geosciences Union annual Nicholas Swanson-Hysell, Francis A. Macdonald, through intensive collaboration with PI Goddéris and PhD fraction of the remaining (about $9000) will cover the meeting in Spring 2019 which gave an opportunity for Yuem Park, Yves Goddéris, Lorraine E. Lisiecki, and student Maffre. travel expanses for the trips to Grenoble but the exact discussions of project research. Collaborative research Oliver Jagoutz (2019) Plate tectonic driven changes in • Travel to the European Geoscience Union meeting accounting is not known yet as the meeting has just accelerated further through a visiting stint in Berkeley weatherability as the long-term control on Earth’s climate for PI Swanson-Hysell to present aspects of project ended. The France-Berkeley Fund has been extremely in June 2019 when Pierre Maffre came for a month of state, Geophysical Research Abstracts. research and have project meeting with PI Goddéris as important for the birth and rise of this project. The team in-person collaboration. Maffre and Park worked in well as his former student Yannick Donnadieu (Directeur is willing to strengthen the links between these institutions close collaboration in consultation with Swanson-Hysell Pierre Maffre, Yuem Park, Nicholas Swanson-Hysell, Yves de Recherche CEREGE, Aix-en-Provence) and pursue our project over the years to come. On the throughout that visit leading to substantial progress. Goddéris (2019). Understanding the interactions between • A collaborative month of research for Maffre at French side, an ERC consolidator grant (SPAWN, PI: B. Following this visit, Swanson-Hysell learned that a major tectonic processes, erosion, weathering and climate. New UC Berkeley to further develop the lithology-dependent Cerutti) has just received a positive recommendation for grant that grew out of these research efforts was funded insights from the DynSoil-GEOCLIM modelling approach, implementation of the GEOCLIM model in collaboration funding to further explore particle acceleration within by the National Science Foundation (more details below). AGU Fall Meeting Abstracts. with Park and Swanson-Hysell. black hole magnetospheres (this information is currently With support from this grant, he hired Pierre Maffre as • Travel for PI Goddéris to Berkeley to present under embargo and should not be published before the a postdoctoral researcher here at Berkeley. In October Yuem Park, Pierre Maffre, Nicholas Swanson-Hysell, research at the American Geophysical Union annual ERC press release scheduled for mid-December). On the 2019, Maffre began this two-year postdoctoral position Francis Macdonald, Yves Goddéris, Eliel Anttila (2019). meeting in December 2019 and collaborate on project US side, Philippov and Parfrey are planning to apply for which is forwarding project research and contributing to Growth of the broader Indonesia archipelago as a driver of research with Swanson-Hysell, Park and Maffre. NASA ATP and NSF grants. a sustained collaboration between Swanson-Hysell and Neogene cooling, AGU Fall Meeting Abstracts. Substantive follow-on funding has been received Goddéris. through the National Science Foundation Collaborative With the progress that we made on the coupled Park, Y., Maffre, P., Goddéris, Y., Macdonald, F.M., Anttila, Proposal: Do arc-continent collisions in the tropics set the weathering-climate model to address the importance of E. and Swanson-Hysell, N.L. (in review, 2020), Emergence Earth’s climate state? (https://www.nsf.gov/awardsearch/ Project #56-2018 rock types with high carbon sequestration potential, we of the Southeast Asian Islands as a driver for Neogene showAward?AWD_ID=1925990). This funding is supporting have used it determine the sensitivity of Earth’s climate cooling, PNAS. Pierre Maffre’s postdoctoral position at UC Berkeley. UC PI: Nicholas Swanson-Hysell (Earth & Planetary state to the presence of specific regions and mountain Science, UC Berkeley) belts. In particular, we pivoted the major focus of our 4) Comment on the collaborative nature of this FRANCE PI: Yves Goddéris (Observatoire Midi- research into seeking to understand cooling on Earth project, highlighting aspects that have fostered Pyrénées, CNRS - Université Toulouse) over the past 15 million years which led to the onset of continuing relationships between French institutions PROJECT TITLE: New paleogeographic models and the glaciation in the Northern hemisphere. We have found and UC campuses. Will future collaboration occur as a onset of a major glacial event in the Ordovician that the emergence of the Southeast Asian islands, a result of this project? MONTH/YEAR OF AWARD ACTIVATION: July 2018 modern-day hotspot of CO2 consumption played a major 42 | France-Berkeley Fund Annual Report 2019-20 Annual Report 2019-20 France-Berkeley Fund | 43 FINAL REPORTS FINAL REPORTS 2018-19 2018-19

Project #61-2018 • Donagh Coleman (Doctoral Student, UCB) corresponding interests was the best way to initiate • Yoshika Crider (Doctoral Student, UCB) substantial scholarly exchange and cooperation. The UC PI: Alexander Von Rospatt (South and Southeast • Jake Dalton (Associate Professor, UCB) workshop was organized in thematic panels that helped Asian Studies, UC Berkeley) • Ryan Damron (Doctoral Student, UCB) generate cohesion among participants and substantial FRANCE PI: Stéphane Gros (CNRS, Centre d’études • David Germano (Professor, UVA) discussion. The follow up event held on September 26 himalayennes) • David Gray (Associate Professor, Santa Clara) allowed for a constructive discussion on yet a different PROJECT TITLE: New Directions in Himalayan Studies • Stéphane Gros (Researcher, CEH) theme, attesting to the convergence of research interests MONTH/YEAR OF AWARD ACTIVATION: October 2018 • Fernand Meyer (Professor Emeritus CEH) between Researchers at the Centre d’études himalayennes • Kunsang Namgyal-Lama (Postdoctoral Student, CEH) and Faculty and students associated with the Himalayan 1) Describe the work accomplished, in relation to the • John “Zim” Pickens (Doctoral Student, UCB) Studies program hosted at the Institute for South Asia original project description. • Fabien Provost (Doctoral Student, CEH) Studies. It is our hope that the collaboration between the • Isha Ray (Professor, UCB) two institutions will continue beyond, likely as part of a Building on the launch of a Himalayan Studies initiative • Caroline Sarrazin (Doctoral Student, CEH) larger network of institutions promoting Himalayan two years ago, this project set as its main goal to • Nicolas Sihlé (Researcher, CEH) Studies. invigorate Himalayan Studies on UC campus, and establish • Joëlle Smadja (Director of Research, CEH) the foundations for a collaboration with the Centre • Gérard Toffin (Director of Research Emeritus, CEH) 5) Give a final accounting of how the France-Berkeley d’Études Himalayennes at the CNRS (France). To this • Romain Valadaud (Doctoral Student, CEH) Fund award was spent. Do you envision soliciting end, the main endeavor has been to host a three-day • Alexander von Rospatt (Professor, UCB) additional outside funding for this or related projects international workshop: the event took place on March • Keiko Yamanaka (Lecturer, UCB) in the future, and if yes, from where? 1-3, 2019 (in 370 Dwinelle Hall, UC Berkeley), and 20 • (Non-UCB or CEH/CNRS collaborators were invited as presentations were included, half of them by doctoral discussants) Of the original $11,300 grant received from the France- students from the two partner institutions. This was the Berkeley Fund was chiefly spent to cover expenses for the largest event ever for Himalayan Studies at UC Berkeley, 3) List all publications resulting from this project. March 1-3 Workshop, for a total of $9,719.63. and it brought together academics and graduate students Include journal titles and issues/dates. In the framework of this collaborative project, additional from both institutions working on the Himalayan region funding was used to complement the FBF award: the in the Humanities and Social Sciences (geography, history, The participants of the panel on “Water Management” partner institution (CEH-CNRS) contributed to the travel art history, anthropology, religious studies, environmental are planning an edited collection of abbreviated papers, expenses for the French scholars, for a total amount of: studies). The event was well attended by colleagues and we are also exploring other possibilities of publishing $6,140 (5,465€). At the time of the Interim report, the and students from UC Berkeley, and the public beyond select contributions to the workshop, held on March 1-3, remaining balance of the France-Berkeley Fund award campus. To foster continuing relationship between the 2019. stood at $1,580.37. For the organization of he follow up Centre d’Études Himalayennes and the Institute for A conference report will be included in the Winter 2019, event on September 26, 2019, we have spent $1,162.98 South Asia Studies and its affiliated Himalayan Studies issue no. 54, of the European Bulletin for Himalayan leaving a positive balance of $417.39. It is our hope that this program, we have organized a small follow up Workshop, Research. The issue is still forthcoming and despite is remaining balance can be used for a follow-up Himalayan which took place of September 26, 2019. At this occasion, dating to winter 2019, it will be forthcoming in spring Studies event and we are filing an extension request to this Keiko Yamanaka (UCB) and Tristan Bruslé (CNRS), both 2020. We will submit a copy to the France-Berkeley Fund end. specialists of migration issues in the Himalayas, presented once the conference report has been published their work on a topic that had not be included in the March Workshop 4) Comment on the collaborative nature of this project, highlighting aspects that have fostered 2) Give the names and ranks of all project participants. continuing relationships between French institutions and UC campuses. Will future collaboration occur as a The participants in the main Workshop and follow up result of this project? event were: • Elizabeth Allison (Associate Professor, CIIS) This collaborative project resulted from sustained • Kris Anderson (Doctoral Student, UCB) exchanges over the previous year between the two • Olivia Aubriot (Researcher, CEH) grantees, Alexander von Rospatt and Stéphane Gros. The • Zack Beer (Doctoral Student, UCB) continuous presence of the latter on UCB campus as a • Patricia Berger (Professor Emeritus, UCB) Visiting Scholar during the months prior to the planned • Daniela Berti (Researcher, CEH) Workshop allowed for a smooth coordination of the • Tristan Bruslé (Researcher, CEH) French and American teams. • Tracy Burnett (Doctoral Student, UCB) As anticipated the Workshop held in March where select • Lawrence Cohen (Professor, UCB) faculty and students of the Centre d’Études Himalayennes came to Berkeley to meet with faculty and students with 44 | France-Berkeley Fund Annual Report 2019-20 Annual Report 2019-20 France-Berkeley Fund | 45 INTERIM REPORTS INTERIM REPORTS 2019-20 2019-20

Project #3-2019 to apply these funds toward travel expenses from France set the stage for a publication. At this stage, it is early to to add the ADAM code into the other thermochronologic to UCB. This will depend on the status of international predict whether this will be the case and the journal where data modeling program: HeFTy UC PI: Richmond Sarpong (Chemistry, UC Berkeley) travel regulations. Breakdown of Expenses to date: the work will be published. A substantial amount of work is (6) General planning and preparation for the thermal France pi: Virginie Vidal (Chimie ParisTech) Communications (FedEx shipment of sample products still necessary and publication will probably occur after the history modeling workshop: QTQt and HeFTy PROJECT TITLE: Enhancing the Medicinal Activity of from UC Berkeley to Paris Tech): $134 conclusion of the France-Berkeley program. - Deep dive into every feature in QTQt (with Dr. Piperidine Derivatives by Late-Stage Derivatization International Travel to attend scientific conference to Gallagher while Willett and Abbey were in France) MONTH/YEAR OF AWARD ACTIVATION: December 2019 promote work from this project: $878 - Brainstorming and solidifying workshop set-up Purchase of ligands and organometallic reagents at Paris and instruction plan (conversations both in France with 1) What is the current status of the project? What has Tech $415 Gallagher and in the following months with Dr. Ketcham: been achieved? How does this relate to the original Total= $1,427 Project #5-2019 creator of HeFTy and the Thermo2020 conference projected timeline? coordinator) 3) What remains to be done for this project? When will UC PI: David Shuster (Earth & Environmental Sciences, - Preparation and testing of workshop learning UC Berkeley) The goal of this collaboration project was to develop a the project be completed? objectives and activities France pi: Kerry Gallagher (Université de Rennes 1) late-stage enantioselective derivatization protocol for Project progress is currently on track with the original PROJECT TITLE: Improving interpretations of piperidines and other azacycles. The ability to effect this The comprehensive evaluation of enantioselective proposed timeline. thermochronometric data through updates to overall transformation would then lead to rapid access hydrogenation conditions for the enamide substrates modeling programs and user education to medicinally relevant compounds. A key aspect of this shown in the scheme on the previous page remains 2) Indicate how much money has been spent to date. MONTH/YEAR OF AWARD ACTIVATION: October 2019 plan hinged on our ability to effect an enantioselective to be accomplished. In addition, a full investigation of How much do you anticipate spending? hydrogenation of a cyclic eneamide intermediate, which conditions to form the enamide substrates using the 1) What is the current status of the project? What has would be prepared in four steps from the precursor methods for C–C cleavage/beta hydride elimination that The trip to Rennes for Abbey and Willett totaled $4,651.93, been achieved? How does this relate to the original saturated azacycle using methodologies developed have been developed in the Sarpong group will need to be which was well within the proposed budget of $6,600. projected timeline? in the Sarpong laboratories. In order to test the key completed. The remaining costs include transportation, lodging, and hydrogenation step (carried out in the laboratories of hosting of the collaborative workshop in Santa Fe, NM in As proposed, postdoctoral scholar Alyssa Abbey and Prof. Vidal), the Sarpong group has prepared the requisite 4) Comment on the collaborative nature of the 2021. These costs were estimated to total no more than then-graduate student Chelsea Willett traveled to the enamide precursors using alternative, more established, project. Highlight aspects of the project that have $3,000 at the time of our FBF application submission. The Université de Rennes department of Geosciences to literature methods. The Vidal laboratory has evaluated the fostered continuing relationships between French remaining funds ($8,890.00 — $4,651.93 = $4,238.04) will work in-person with Professor Kerry Gallagher. The trip enantioselective hydrogenation of one of these substrates institutions and UC campuses. be more than sufficient to cover these expected costs. took place from 23 October through 12 November 2019 (see below). Initial results are promising but conversions Willett reimbursement amount: $3,495.49 covering airfare, and provided ample time to learn about how the QTQt are The two research groups have communicated consistently train tickets, etc. software was constructed and is managed. While on-site low, highlighting the difficulty of this transformation. about the best set of conditions to pursue for the Abbey reimbursement amount: $1,156.44 covering lodging, in Rennes, Abbey and Willett worked with Gallagher to add Relationship with original timeline: Unfortunately, our enantioselective hydrogenation. The group of Prof. food, etc. the alpha-damage annealing model (ADAM; from Willett et goals of evaluating the other enamide substrate shown Vidal has shared literature pertaining to related reports Total already spent = $4,651.93 al. 2017) to the QTQt software. In addition, Abbey, Willett, above, which was planned as a part of our initial six-month of enantioselective hydrogenations and the Sarpong and Gallagher were able to spend valuable time discussing goal, have been curtailed by the COVID-19 crisis, making group has shipped samples to France to test in the 3) What remains to be done for this project? When will the best practices for software implementation, work it difficult to establish which of the two substrates will be enantioselective hydrogenations. The success of the the project be completed? through the step-by-step modeling process with some ideal for our purposes. enantioselective hydrogenations will set the stage for a longer term collaboration to expand the scope of these new thermochronometric data from Colorado, USA, and As described above, the remaining portion of this reactions. begin planning for the second portion of the collaboration project is developing and hosting a collaborative 2) Indicate how much money has been spent to date. in September 2020. How much do you anticipate spending? thermochronometry workshop at the next International 5) Will this project result in a publication? (Indicate Conference on Thermochronology in Santa Fe, NM in 2021 form of publication, if possible.) Project Achievements to date: (postponed from September 2020 to a 2021 date, due to A total of $1,012 has been spent on this project to date, (1) New diffusion damage annealing model: ADAM leaving a remaining balance of $9,988. At this time, no COVID-19). This workshop will be held at the conclusion of The success of the enantioselective hydrogenations will (Willett et al., 2017) has been added to the next version of additional expenses are projected until Prof. Vidal is able the 17th International Conference on Thermochronology QTQt and will be an excellent opportunity to involve more high- (2) Willett and Abbey presented research that is impact collaborators. Willett, Abbey, and Gallagher will run related to and which will benefit from the current project several workshops for both beginner and intermediate to the scientists at the Université de Rennes (department users of QTQt. Additionally, Abbey will present on seminars) the new testing and learnings related to techniques (3) New version of QTQt has been released to the and applications of thermal history modeling of low- community of users temperature chronometers for both programs (QTQt and (4) Testing of ADAM in new QTQt version (Abbey HeFTy). while in France and in the months following) The current project timeline is unknown as (5) Willett has now begun working with Dr. Ketcham the new conference dates are not yet set for 2021; 46 | France-Berkeley Fund Annual Report 2019-20 Annual Report 2019-20 France-Berkeley Fund | 47 INTERIM REPORTS INTERIM REPORTS 2019-20 2019-20

however, Abbey and Willett are working with the primary and paired journal publications in Geosphere as part of interfacing the efficient 1D solver DSM (Direct Solution December 2019 was covered by INRIA . Unfortunately, due conference organizers to ensure a cost-effective and of an educational contribution and special volume. Method) with RegSEM (Adourian and Masson). We to COVID-19, the workshop has been postponed to a later productive session for all. Due to the global pandemic, we Conversations with the Geosphere editors are in progress. started testing the implementation of a hybrid inversion date (TBD), and for the time being Sevan Adourian cannot anticipate project completion in late 2021. The goal is to create a special volume specific to the methodology that aims to take advantage of the accuracy go back to France because of restrictions on international topic of modeling methods and techniques for handling of travel. He will likely not go to France this summer. Given 4) Comment on the collaborative nature of the thermochronologic data. The companion papers on the adjoint methodology for computing gradients, and the some uncertainties about the situation in Fall 2020, we project. Highlight aspects of the project that have QTQT and HeFTy (co-authored by Dr. Abbey) will act possibility to compute a normal mode approximation of would like to ask for an exceptional 1 year extension of this fostered continuing relationships between French as the guides and overview for the special volume. The the grant, as we do hope to be able to catch up on our institutions and UC campuses. thermochronologic community will be informed of this Hessian, which accelerates the convergence of the inverse exchanges with physical presence if not this Fall, then next volume and solicitations for additional publications within problem. While this is still at the stage of synthetic tests, Spring and early summer. While in France, Abbey and Willett were able to work the volume theme will be advertised. Abbey and Willett the side-by-side with Professor Gallagher to learn first-hand will use this call to submit a focused contribution on the application to real data should be starting promptly 3) What remains to be done for this project? When will how the software commonly used to interpret apatite sensitivity and utility of different radiation damage models (Adourian with help from Masson). Researchers at the project be completed? thermochronological data is managed. Meeting face- and how they can be used within these programs. Magique-3D started developing a new generation solver to-face provided all parties with an opportunity for for modeling elastodynamic wave propagation through Now that the above developments have been completed, productive back-and-forth dialogue about how specific the Earth that is designed in close collaboration with the we are considering applications to infer the Earth’s settings within the QTQt software are selected, when Project #10-2019 researchers at the BSL in order to meet their specific internal and why features are added to the software, and how needs. This solver relies on a novel method called the structure, in particular, to obtain higher resolution images best to apply the software to questions in Earth science. UC PI: Barbara Romanowicz (Earth & Planetary Science, Distributional Finite Difference method (DFD) which of the ”fat plumes” imaged by global tomography. We are Abbey and Willett also engaged with Professor Gallagher’s UC Berkeley) combines advantages of the finite difference method (FD) currently carrying out the last steps needed before research group and discussed topics ranging from France pi: Hélène Barucq (Magique 3D - INRIA, and of the spectral element method (SEM). In the future, investigating the morphology of the plume under the research ideas to laboratory management. Furthermore, Université de Pau) this software will replace the solvers based on the element Yellowstone hotspot in North America. We are proceeding Abbey and Willett opted to give professional research PROJECT TITLE: Development and Application of method (SEM) that are currently being used at the BSL. with data selection and the inversion setup prior running talks to the Department of Geosciences at Univ. de Advanced Seismic Imaging Techniques for Key Target large scale computations at NERSC. Preliminary results Rennes while on-site, as an opportunity to share brand Structures in the Deep Earth B - Investigating the use of novel misfit functionals in should be available in the coming months. To facilitate new results with others in our field and make the most MONTH/YEAR OF AWARD ACTIVATION: September 2019 global seismic tomography exchanges and transfer of knowledge a mini-symposium of the France-Berkeley Fund support. Abbey, Willett, and Several steps have been taken to adapt novel waveform was scheduled at the University of Pau,France (location Gallagher continue to work together in preparation for 1) What is the current status of the project? What has tomography algorithms recently developed at Magique- of Magique3D) at the end of June 2020. Because of the conference workshop, further strengthening the ties been achieved? How does this relate to the original 3D to global seismology. These algorithms rely on a the COVID pandemic, this mini-symposium has been between the research groups at both the University of projected timeline? new misfit functional which allows to employ different postponed with a new date not yet established, hopefully California, Berkeley and Université de Rennes. acquisition setups (e.g. source positions) for the modeling in Fall 2020. However, we organized video-conference A - Deploying Box-Tomography for Imaging Mantle Plumes (i.e. the computation of synthetic seismograms) and the meetings to discuss results, progress and perspectives 5) Will this project result in a publication? (Indicate A functional interface for the full implementation of Box observations. The methodology was formerly developed related to our collaboration. form of publication, if possible.) Tomography has been developed, it allows us to couple and implemented in the frequency domain at Magique- two 3D solvers for the wave propagation in the Earth and 3D. An extension of the method to the time domain has 4) Comment on the collaborative nature of the Yes. At present 2-3 peer-reviewed journal publications thus significantly reduce the computations cost of the been completed and successfully tested, this will allow to project. Highlight aspects of the project that have are projected. The improvements made to QTQt and forward modeling in seismic tomography. In particular, the conduct further investigations using the BSL tomography fostered continuing relationships between French discussions Willett and Abbey had with Dr. Gallagher following steps have been completed: workflow which fully relies on time domain modeling. institutions and UC campuses. while in France showed that there are many gaps in the - The global wave propagation solver Specfem 3D globe In addition, we showed that seismological data can be understanding users have for the programs that model has been upgraded in order to compute Green’s functions accounted for in exploration geophysics to improve the Support from the France-Berkeley Fund permitted thermochronologic data. Both programs (QTQt and in our resolution seismic imaging techniques. The usage of substantial exchanges between Magique-3D and the BSL. HeFTy) are widely used but are often used incorrectly or current reference Earth model (SEMUCB)(Masson) seismological data for seismic imaging could be achieved In particular, S. Adourian visited Magique 3D for 2 weeks in not used to their fullest potential because of the inherent - The local wave propagation solver RegSEM globe has by combining a newly developed misfit functional and the summer of 2019 (initiated thanks to the FBF project, objective decisions that must be made when selecting been upgraded so that the wavefield can be recorded and some hybrid modeling but supported by INRIA as the FBF funds were not yet which data to model and which model parameters to stored at the boundary of the modeling domain (Adourian techniques developed for Box-Tomography. available) and established a fruitful ongoing collaboration change. Although these topics are to be addressed in and Masson) with Yder Masson, Sevan and Yder maintain regular - We implemented real-time compression for an improved the workshops at the next International Conference 2) Indicate how much money has been spent to date. exchanges through video-conference meetings. This management of computed data (Masson). In addition, for on Thermochronology, an in-depth assessment of the How much do you anticipate spending? interaction is greatly beneficial to the development of the techniques used to model data in both programs will be the specific cases where higher frequencies seismograms novel tools needed to image localized structures in the need to be calculated, we have been working towards invaluable and much more far reaching than a conference We have not spent any of the funds yet. We were saving deep Earth, indeed, it allows to efficiently port and adapt an implementation with faster, 1D solvers outside of the workshop. them for Sevan Adourian’s travel this summer (2020) and theoretical and methodological developments carried target region coupled with accurate 3D solvers inside the The current plan for publication is a collaboration for the workshop which was planned on June 25-26th, so out at Magique-3D so they can be used for applications in target region. In particular, we have completed the task between QTQt and HeFTy users with two peer reviewed that the travel of Yder Masson to Berkeley and AGU in global seismology. Such transfer of knowledge would be 48 | France-Berkeley Fund Annual Report 2019-20 Annual Report 2019-20 France-Berkeley Fund | 49 INTERIM REPORTS INTERIM REPORTS 2019-20 2019-20

much more difficult otherwise. Researchers and students Project #16-2019 of qubit, whose measurement operators are spanned by understood. The remaining scientific objective is to from Magique-3D (Hélène Barucq, Pierre Jacquet, Rose the generators of SU(2). Song is currently applying the investigate their optimality, and improve accordingly. Cloé Mayer and Yder Masson) attended the American UC PI: Birgitta Whaley (Chemistry, UC Berkeley) approach of defining In a normal situation without COVID-19, we would have Geophysical Union - Fall Meeting 2019 in San Francisco, on France pi: Pierre Rouchon (Mathématique et feedback controls by a combination of deterministic and expected to be able to complete studies of adaptive that occasion, they visited the BSL and several meetings Systèmes, Mines ParisTech) stochastic functions, which both the Paris and Berkeley measurements for both a qubit and a qutrit, with some were organised together with Barbara Romanowicz, Sevan PROJECT TITLE: Quantum Feedback Control for groups have used previously. When we have understood progress on the theory for general qudits. However, in Adourian and Florian Faucher (in visio). This allowed us Information Processing how to make optimal adaptive measurements for the current situation, we cannot provide a firm date for to discuss and envision applications of recent theoretical MONTH/YEAR OF AWARD ACTIVATION: September 2019 purification of a qubit, we shall then return to the qutrit completion of the project. This is due both to the inability results, for example the usage of a new misfit functional, system with which Gerardo Cardona had started out last of the Paris and Berkeley groups to meet in person, and to to address problems encountered in global seismology. 1) What is the current status of the project? What has fall, and apply the optimal adaptive approach to this more the change in all of our academic and personal schedules As a side bonus, the above interactions induced been achieved? How does this relate to the original complex dynamical system. that have modified our daily routines and forced us to additional collaboration between Magique-3D and UC projected timeline? We had scheduled a one-month visit of the modify our working schedules in this time of the COVID-19 Berkeley on other topics. In particular, Rose-Cloé Meyer ( Berkeley student to Paris for March 2020, as well as a pandemic. We therefore ask for an extension of another PHD Student - Magique -3D ) started a close collaboration Gerardo Cardona, a PhD student from the Paris group, 2-day visit of Birgitta Whaley to the Paris group at the year to complete the project. with Steve Pride (EPS/BSL-LBNL) on the modeling of visited the Berkeley group for one month in October 2019. beginning of April, following a conference in France at that seismo-electric phenomena in poroelastic media. Rose- Gerardo Cardona gave a seminar summarizing the main time. Unfortunately, both of these visits from the Berkeley 4) Comment on the collaborative nature of the Cloé visited Steve at the LBNL for a couple months since results of his PhD manuscript in progress at that time. This group to the Paris group had to be cancelled because project. Highlight aspects of the project that have this project started and will continue working with Steve in included his work on Lyapunov techniques for analysis of of the COVID-19 situation. COVID-19 situation will cause fostered continuing relationships between French the future. controllability and stabilizability of quantum systems, as some delay in completion of our planned work. We are all institutions and UC campuses. well as estimation of the exponential convergence rate in connected to the internet and are able to communicate 5) Will this project result in a publication? (Indicate closedloop control for QND systems, with application to by email and to discuss by Skype, which is very useful. Scientifically and collaboratively, the project has so far form of publication, if possible.) continuous-time quantum error correction for the 3-qubit However, this is not the same as meeting and discussing turned out to be a great success. Gerardo Cardona code under bit-flip errors. During his visit we identified the in person, particularly when exploring new areas/ideas brought new insights to the Berkeley group from the Paris The results obtained so far have been the object of joint problem of quantum state purification as a good target and technical difficulties that arise during the research. group’s use of Lyapunov functions to assess stabilization presentations in several international meeting: for combining the joint expertise of the Paris and Berkeley The work is generally progressing as we had envisaged in rates and their use of stochastic noise functions for [1] Imaging the Root of the Yellowstone Hotspot: groups, with the additional challenge to extend this from our original proposal, and we plan to set up visits of the feedback control. We have identified a specific project, Preliminary Results Using “Box Tomography”, S Adourian, the usual quantum bits (‘qubits’ or two-dimensional Berkeley group members to Paris as soon as the COVID-19 quantum state purification, that is of interest to both Y Masson, B Romanowicz - AGU Fall Meeting 2019, San quantum systems) to the higher dimensional qudits situation has subsided and international travel is allowed groups and that can take advantage of both the shared Francisco, CA, USA (d-dimensional quantum systems) that are becoming of and is safe again. expertise of the two groups and the complementary [2] Full Reciprocity-gap Waveform Inversion in Global and increasing interest in experimental implementations of expertise that the two groups possess. While the Berkeley Regional Seismic Imaging. H Barucq, F Faucher, YJ Masson, quantum information processing. 2) Indicate how much money has been spent to date. group is now moving the calculations ahead, the Paris B Romanowicz - AGU Fall Meeting 2019, San Francisco, CA, We then started a joint project on purification How much do you anticipate spending? group has been expanded by the addition of Alain Sarlette USA of qudit systems by continuous quantum measurements, (https://users.ugent.be/~asarlet/), a colleague of Pierre [3] Modeling seismic wave propagation through the Earth focusing in the first instance on understanding the Expenses for the visit of Gerardo Cardona in October Rouchon at INRIA-Paris. The Paris group is also expecting a for imaging localized structures. stochastic dynamics of a qutrit under different 2019: 6577 USD. We expect to spend the remainder of the new postdoc in August/September who will join the work Yder Masson, Helene Barucq, Julien Diaz, Barbara combinations of non-commuting measurements taken funds (4423 USD) for the visit of Song Zhang to Paris, once on this project. Romanowicz, and Sevan Adourian - EGU General Assembly from the generators of SU(3). After Gerardo Cardona the 2020, Vienna, Austria. returned to Paris, he graduated and took up a position in COVID-19 situation is no longer a danger. A manuscript is in preparation (Adourian, Masson a company, so could not continue these calculations, but 5) Will this project result in a publication? (Indicate and Romanowicz, for submission in July 2020) on the his initial work showed clear connections with the QND 3) What remains to be done for this project? When will form of publication, if possible.) successful stabilization framework of the Paris group, which we plan the project be completed? coupling of the global SPECFEM solver and the regional to continue in the coming months. In the meantime, we Thus far we have no common publication f rom the FBF RegSEM solver in the case when both sources and stations have continued work in a related but slightly different We shall reschedule the one-month visit of graduate project. However, we do each have publications that are are outside the target region. We expect that future direction with the graduate student in the Berkeley group. student Song Zhang to the Paris Group for some time in related to the general scientific program of our joint work results on the investigation of the morphology of the This is Song Zhang, who is now focusing on introducing Fall 2020 (provided the COVID-19 situation is resolved and which we have discussed in planning the joint project plume under the Yellowstone hotspot will be the object of the notion of control by adapting the measurement satisfactorily). We shall also likely schedule a short visit on quantum state purification. These are: one or more joint publications in peer reviewed scientific axis as a result of making a continuous feedback of the of Professor Birgitta Whaley to the Paris group and - PhD thesis of Gerardo Cardona (November 2019); a journals. measurement outcome at time of Professor Pierre Rouchon to the Berkeley group at communication to the IFAC NOLCOS 2019; a journal paper t, to determine the axis of the measurement at time t+dt. some point during the next 12 months. The project has in Automatica 2019 An undergraduate researcher also expressed interest started a new area of work, and there are various short - a communication to the IFAC 2020 World Congress; a in this general area of research, and he has now joined term and longer-term goals that we can now identify. journal paper submitted to Physical Review A, posted on the project and is working together with Song. We are Some strategies for fast purification and stabilization the preprint archive at arXiv:1910.02487; a journal paper currently carrying this work out on the simpler system by measurement adaptation have been laid out and submitted to Physical Review X, posted on the preprint 50 | France-Berkeley Fund Annual Report 2019-20 Annual Report 2019-20 France-Berkeley Fund | 51 INTERIM REPORTS INTERIM REPORTS 2019-20 2019-20

archive at arXiv:02002.11248 (flight + accommodation + food), $3000 soil-dwelling spider diversity along a structural gradient of greatly aided by our planned in-person meeting. We had The visit of Gerardo Cardona to Berkeley has Flight to Hawaii for Julien Pétillon, $841 + $700 neotropical habitats. Diversity 12: 81. tentatively scheduled a joint France-Berkeley meeting enabled our collaboration to identify a clear open (accommodation & food for 7 days) in Paris this summer, but that has now been postponed question and a viable approach with which to address Flight to Hawaii for Denis Lafage $1,477 + $800 due to the pandemic. We are now currently planning for it. Once the mathematical and numerical studies have (accommodation & food for 8 days) something for the fall, travel permitting. been developed, it is clear that we will have material for Lab and field supplies, $556 publication in a scientific journal on quantum control and/ Registration + accommodation for the European Congress Project #24-2019 4) Comment on the collaborative nature of the or a journal in quantum physics. of Arachnology in Greifswald (delayed for 1 year, until project. Highlight aspects of the project that have 2021), $800 UC PI: Uros Seljak (Physics, UC Berkeley) fostered continuing relationships between French France pi: Benjamin Wandelt (Institut d’Astrophysique institutions and UC campuses. 3) What remains to be done for this project? When will de Paris) the project be completed? PROJECT TITLE: Optimally mapping the dark matter in The one working meeting to-date which was been enabled Project #19-2019 the universe with the CMB by these funds aided in finishing the central piece of the Because of the current global situation with COVID19, MONTH/YEAR OF AWARD ACTIVATION: November 2019 proposal. The planning of this proposal, which involved UC PI: Rosemary Gillespie (Environmental Science, the main field work to Hawaii of this project has been all postdocs, and the subsequent reception of the award, Policy & Management, UC Berkeley) postponed as well as the phylogenetic and population 1) What is the current status of the project? What has has helped keep everyone focused on the tasks which we France pi: Julien Pétillon (Université de Rennes 1) genetic analyses resulting from this fieldwork. This trip has been achieved? How does this relate to the original proposed, and on continuing the collaborations between PROJECT TITLE: The hidden side of Heaven: evolutionary been postponed to June 2021. The resulting analyses will projected timeline? our institutions. With postdoc Francois Lanusse having story of Hawaiian lava caves’ wolf spiders be conducted from June 2021 to December 2021, date on moved to France for a permanent position but having MONTH/YEAR OF AWARD ACTIVATION: December 2019 which the project will be completed. Our proposed project is progressing along the original kept close ties with the group, there is potential for him to timeline. As we discussed in the proposal, there is one involve others in work related to this proposal as well. 1) What is the current status of the project? What has 4) Comment on the collaborative nature of the “central” piece of the analysis, and several other branches been achieved? How does this relate to the original project. Highlight aspects of the project that have which depend on this. Postdoc Marius Millea along with 5) Will this project result in a publication? (Indicate projected timeline? fostered continuing relationships between French PI Ben Wandelt has now finished this central part, and form of publication, if possible.) institutions and UC campuses. the results have been submitted for publication (preprint The project was progressing according to the timeline available at https://arxiv.org/abs/2002.00965). Postdocs One publication mentioned above has already been until the outbreak of the COVID19 pandemic. From This project requires a strong collaboration between Millea and postdoc Emanuel Schaan have since been submitted: https://arxiv.org/abs/2002.00965 We expect December 2019 to March 2020, the DNA of the first Dr. J. Pétillon (University of Rennes, France), for his working on the proposed exploration of foreground several others as well would come from the other Hawaiian cave wolf spiders we got from museum and expertise in dispersal ecology and wolf spiders biology mitigation techniques, building off of this paper. They proposed sub-projects. collaborators was extract, sequenced and is undergoing and Dr. R. Gillespie (University of California, Berkeley) for have some preliminary results which have been presented phylogenetic analysis. her expertise in island biogeography, spider ecology, and at conferences, and will be writing up these results for We were supposed to do the major field work of this evolution. The implication in this project of Kaïna Privet, publication. Since receiving this award, postdoc Francois project this summer. The objectives of this field work is PhD candidate in France, advised by Dr. Julien Pétillon Lanusse has been awarded a CNRS position at Univsité to broadly collect fresh cave wolf spiders to complete and co-advised by Dr. Rosemary Gillespie, have fostered Paris-Saclay, has moved to Paris, and continues to Project #26-2019 the phylogeny and to investigate the population genetics continuing the relationship between our two countries. collaborate with the group. of these Hawaiian cave wolf spiders. We had purchased UC PI: Truman Young (Plant Sciences, UC Davis) tickets for this coming May/ June, but they were cancelled 5) Will this project result in a publication? (Indicate 2) Indicate how much money has been spent to date. France pi: Elise Buisson (Institut Méditerranéen de because of COVID19. The French borders are closed until form of publication, if possible.) How much do you anticipate spending? Biodiversité et d’Ecologie, Avignon Université) further notice and all newcomers to Hawaiian territory PROJECT TITLE: Taking priority effects into account must stay in quarantine for 15 days. Consequently, the The project will produce several publications, as is evident We have spent $1781 on one trip to Paris by postdoc in restoration and invasive species control field current situation in France and Hawaii does not allow from the research results we have obtained already and as Marius Millea in which he met with PI Ben Wandelt and experiments us to secure this trip soon and we have then decided to summarized above. However, we still have to perform the they worked together on this project. This meeting came MONTH/YEAR OF AWARD ACTIVATION: November 2019 reschedule it to June 2021. fieldwork, so the core publications must wait until we can right as these results were being prepared to submit for complete this work. publication, and the ability to work together in person on 1) What is the current status of the project? What has 2) Indicate how much money has been spent to date. We have published two papers that have relevance to the this greatly helped this along. been achieved? How does this relate to the original How much do you anticipate spending? proposed research: projected timeline? Pétillon, J., Privet, K.; Roderick, G.K.; Gillespie, R.G.; Price, 3) What remains to be done for this project? When will The award was for $11,000. We have spent 20% of the D.K. 2020. Non-native spiders change assemblages of the project be completed? The project is running as expected. Achievements so far: funds on publications (see below), totaling $2,226. The Hawaiian forest fragment kipuka over space and time. organized and ran 1 workshop and 1 symposium at SER remaining $8,774 will be spent next year as follows: NeoBiota 55: 1-9. Postdocs Marius Millea and Emanuel Schaan have World Conference (South Africa); 2 presentations at the Speleology training for graduate student Kaïna Privet, Privet, K.; Vedel, V.; Fortunel, C.; Orivel, J.; Martinez, Q.; made significant progress on their piece, and this can 13th Annual Graduate Student Symposium in Ecology (UC $600 Cerdan, A.; Baraloto, C.; Pétillon, J. 2020. Relative efficiency be completed over the next several months. Other Davis); several draft papers; analyzed data; 1 fellowship Field trip to Hawaii/Berkeley/Sacramento for Kaïna Privet of pitfall trapping vs. nocturnal hand collecting in assessing projects are still at more exploratory phases, but will be proposal was submitted to continue the project next year 52 | France-Berkeley Fund Annual Report 2019-20 Annual Report 2019-20 France-Berkeley Fund | 53 INTERIM REPORTS INTERIM REPORTS 2019-20 2019-20

September 2019: Pr. Young & Dr. Buisson met project. Highlight aspects of the project that have influences its resistance to invasion the project be completed? at the SER (Society for Ecological Restoration) World fostered continuing relationships between French 5. Priority effects for the restoration of semi-natural dry Conference in South Africa as planned. Pr. Young and Ms. institutions and UC campuses. grasslands in the Alps 1. Completion of the R package, ASVclustr for clustering Hess (Ph.D. fellow advised by Dr. Buisson) co-organized a amplicon sequencing data for use in the generalized lotka workshop on priority effects with Cara Nelson and Renaud Ms. Hess has applied for a fellowship to come back to volterra model. Jaunatre, to which they all attended. (see photo n°1 at the UC Davis next winter (2020-2021) with a new project on 2. The addition of a model parameter to account for end of the document) Dr. Buisson organized a symposium priority effects. Dr. Buisson and Pr. Young are looking the impact of coprophagy or dietary supplements on on tropical grassland restoration “Science to the service into collaborating on the KLEE project (https://tpyoung. Project #27-2019 microbiome interactions. of tropical grassland restoration: challenges and future ucdavis.edu/klee) next (initially, field work was being 3. Simon Labarthe has been working with us on a prospects”. planned for November 2020, but the schedule may have UC PI: Andreas Bäumler (Medical Microbiology & project where he is modeling interaction between fiber January 2020 – March 2020: Dr. Buisson and 2 to be changed depending on covid19 development in the Immunology, UC Davis) degradation in the gut microbiome and salmonella Ph.D. fellows (Ms. Hess & Ms. Durbecq) arrived at UC Davis world and in Africa more particularly. Dr. Buisson and Pr. France pi: Simon Labarthe (MalAGE, INRA) infection using human fecal metagenomic data and on January 2nd. Ideas, data and papers were discussed Eviner are in touch and are thinking about more links with PROJECT TITLE: Experimental and mathematical models genomic data of salmonella generated in our lab, and and written (see below) within and outside lab meetings, Dr. Blight (based in France in Dr. Buisson’s institute) for cross-talk : a bifocal would like to come back to complete work on that with Pr. Young and Pr. Eviner. Ms. Hess analyzed her last collaboration on ants and relationships with vegetation. MONTH/YEAR OF AWARD ACTIVATION: December 2019 collaborative project. As stated in section 2, we are unsure data and wrote drafts of a paper on priority effects. Dr. Young is planning visit to Dr. Buisson in Avignon later in as to when that may be due to covid19. Ms. Durbecq analyzed data and wrote drafts of for two 2020. 1) What is the current status of the project? What has papers, one of which will be on priority effects. Both Ph.D. been achieved? How does this relate to the original 4) Comment on the collaborative nature of the fellows participated in the 13th Annual Graduate Student 5) Will this project result in a publication? (Indicate projected timeline? project. Highlight aspects of the project that have Symposium in Ecology (GSSE) held on Friday, February 7th form of publication, if possible.) fostered continuing relationships between French 2020 at UC Davis. 1. Development of a pipeline for preparing experimental institutions and UC campuses. - Durbecq A. Ecological restoration & plant - As a result of a symposium organized on tropical data for mathematical modeling was achieved (and is community assembly of montane grasslands in French grassland restoration at the 2019 SER (Society for still currently undergoing further improvement and Simon Labarthe introduced Connor Tiffany to many Alps following soil disturbance Ecological Restoration) World Conference in South Africa, development). Initial modeling of the data was performed faculty and researchers at the MaIAGE at Inra including - Hess M. Exploring the challenges of translating 1 paper was completed and submitted and 1 paper is being and is currently ongoing. Beatrice Laroche who is a director of research, and ecological theory into the practicalities of managing written. 2. A software tool for this pipeline was developed and at the Inrae in Bordeaux. This will likely lead to future invasive species - The case of limiting similarity (see photo Title of the symposium: “Science to the service of tropical released. This sub-project grew out of the need to write collaborations, where the Baumler lab at UC Davis can n°2 at the end of the document). Ms. Hess applied for a grassland restoration: challenges and future prospects” custom programs to properly cluster and parse the data work with researchers at the MaIAGE with modeling high fellowship from L’Oreal to come back to UC Davis next 1. Silveira FAO, Arruda AJ, Bond W, Buisson E, Durigan G, for use in the MaIAGE generalized Lotka Volterra Model. throughput sequencing data generated from mouse winter (2020-2021) with a new project on priority effects. Fidelis A, Kirkman KP, Oliveira RS, Overbeck GE, Sansevero 3. Connor gave a talk about the modeling work and experiments. JBB, Siebert F, Siebert SJ, Young TP (in review) Myth- the tools he developed at the University of Bordeaux 2) Indicate how much money has been spent to date. busting grassy biome restoration. Restoration Ecology mathematics department. He was originally also going to 5) Will this project result in a publication? (Indicate How much do you anticipate spending? 2. Buisson E, Fidelis A, Overbeck G., Schmidt IB, Durigan give a talk at MaIAGE the following week but had to return form of publication, if possible.) G, Young TP, Veldman J, Arruda AJ, Boisson S, Bond W, to the United States early due to Covid-19. All of the France Berkeley funding has been spent. Dr. Coutinho A, Ignacio de Urzedo D, Kirkman KP, Oliveira RS, Despite the pandemic, we managed to not only adhere So far, this project has resulted in the development of Buisson had planned to stay until the end of April (but Schmitt M, Siebert F, Siebert SJ, Thompson D, Silveira FAO to the original project timeline thus far of modeling a software tool, named ASVclustr, which is currently because of Covid19 issues, her home institution in France (in preparation) A research agenda for the restoration the dataset before Connor returned to the US, we available for download and use from Connor Tiffany’s requested her return earlier: April 18th). Ms. Braschi of tropical and subtropical grasslands and savannas. also developed a novel R package for clustering 16S github repository (https://github.com/connor-reid-tiffany/ (Ph.D. fellow advised by Dr. Buisson) arrived on March Restoration Ecology rRNA amplicon sequencing data for applications where ASVclustr/). Connor plans to write and release a pre- 9th and will be here until April 18th as well. From March - A paper on grassland restoration was also submitted dimensionality reduction for modeling is necessary. print paper on the software tool, and will coordinate onward (2nd semester), other funding sources are used on January 15th. We were invited to revise and the with the scientists he worked with at the MaIAGE on any for the project: Avignon University outgoing mobility manuscript was resubmitted on March 18th. 2) Indicate how much money has been spent to date. publication in a peer reviewed journal. mainly, but also Ecole Doctorale 251 and IMBE – Institut 3. Buisson E, De Almeida T, Durbecq A, Arruda AJ, Vidaller How much do you anticipate spending? Méditerranéen de Biodiversité et d’Ecologie. C, Alignan J-F, Toma TSP, Hess MCM, Isselin-Nondedeu F, Jaunatre R, Moinardeau C, Young TP, Mesléard F, 4776.81 USD has been spent thus far. We anticipate 3) What remains to be done for this project? When will Dutoit T, Blight O, Bischoff A (in review) Key issues in spending another 6000 USD for when Simon Labarthe Project #31-2019 the project be completed? North-western Mediterranean dry grassland restoration. eventually comes to work with us at UC Davis. Restoration Ecology Unfortunately, due to COVID-19 we are unsure of when UC PI: Ksenia Krasileva (Plant & Microbial Biology, UC 2 papers were submitted and are now under revisions. - Two papers on priority effects are being prepared, but Simon Labarthe will be able to travel to work with us in Berkeley) At least 2 more papers are at the state of drafts and will be will be submitted later. For n°4, data is being analyzed and the United States. We request that the remaining funds be France pi: Thomas Kroj (INRAE, l’institut national submitted this spring. for n°5 another round of data needs to be collected in made available at a later date in 2021 if possible. de recherche pour l’agriculture, l’alimentation et June 2020. l’environnement) 4) Comment on the collaborative nature of the 4. How does the order of arrival of species in a community 3) What remains to be done for this project? When will PROJECT TITLE: Bioinformatic identification and 54 | France-Berkeley Fund Annual Report 2019-20 Annual Report 2019-20 France-Berkeley Fund | 55 INTERIM REPORTS INTERIM REPORTS 2019-20 2019-20

functional analysis of disease resistance and 5) Will this project result in a publication? (Indicate audience was composed of UC Berkeley faculty, graduate susceptibility genes to fungal diseases in wheat and form of publication, if possible.) One more Zoom meeting and the final workshop, which students, and undergraduates in English, Romance rice will be used to prepare a publication. Languages, and Sound Studies. We agreed to convene a MONTH/YEAR OF AWARD ACTIVATION: October 2019 It is hard to tell at the moment. As we are expanding second meeting of the colloquium in Paris in spring 2021. collaborative research and exchange of expertise to new 4) Comment on the collaborative nature of the 1) What is the current status of the project? What has areas, it is likely that this new connections enabled by this project. Highlight aspects of the project that have 2) Indicate how much money has been spent to date. been achieved? How does this relate to the original grant will result in co-authored publications. fostered continuing relationships between French How much do you anticipate spending? projected timeline? institutions and UC campuses. We have spent $5,498. We anticipate spending the We have held initial zoom meetings instead of the planned The project created the conditions for the first large-scale remainder of our budget $ $5,502 to support a second visits due to COVID19. We exchanged our expertise on interaction between scholars working on the historical colloquium next spring. plant immune receptor functional analyses and plant Project #45-2019 dimension of algorithmic thinking in France and the US. immune receptor evolutionary analyses. We followed up The two PIs see this as the first stage of a long term series 3) What remains to be done for this project? When will with detailed analyses of specific immune receptor pair UC PI: Massimo Mazzotti (History/CSTMS, UC Berkeley) of collaborations between EHESS and UC Berkeley around the project be completed? RGA4/RGA5 and identified new domains of interest. We France pi: Giovanna Cifoletti (Centre Koyre, EHESS) the topic of the sociohistorical dimensions of artificial have exchanged our tutorial on bioinformatic analyses of PROJECT TITLE: Algebraic language and the algorithm. intelligence and automation. The structure of the project What remains is a second installment of the colloquium protein families. Art of thinking, thinking machines, and machines’ was designed to maximize interaction between the two at the Université Sorbonne Nouvelle, in Paris, provisionally thinking. groups, for example by matching graduate students with titled “Sounding on: Virginia Woolf’s Resonance beyond 2) Indicate how much money has been spent to date. MONTH/YEAR OF AWARD ACTIVATION: September 2019 similar research interests. As a concrete and immediate Modernism,” that will bring Woolf’s echoes into the How much do you anticipate spending? outcome of this choice I can report that spin-off Zoom contemporary moment. We plan to hold this colloquium 1) What is the current status of the project? What has meetings are already taking place that are not formally in April or May, 2021. No money has been spent yet as we had to postpone our been achieved? How does this relate to the original part of our project, organized independently by groups of visits. projected timeline? graduate students from the two institutions. 4) Comment on the collaborative nature of the project. Highlight aspects of the project that have 3) What remains to be done for this project? When will The project is ongoing according to the original timeline. 5) Will this project result in a publication? (Indicate fostered continuing relationships between French the project be completed? Prof. Cifoletti spent part of the fall as a visiting scholar form of publication, if possible.) institutions and UC campuses. affiliated with CSTMS and delivered a series of lectures We plan to continue zoom sessions and continue to and master-classes. Her presence on our campus was A collection of essays on the long durée history of The French and American collaborators on this project develop data analyses. We decided on exchange of key to the formation of a working group that is focusing algorithmic thinking. We see this as the first in a series worked together closely before, during, and after the biological material for analysis of immune receptor on the history of algorithmic thinking. We had our first of publications on the history of mechanization/ colloquium and intend to continue collaborating. We activity and wait for the end of the lock-down sending brainstorming workshop in November 2019, and had automation/artificial intelligence. imagine that the second meeting of the colloquium in the material. Through the discussions enabled by this planned to continue our activity during Spring 2020 with Paris will deepen these collaborative relationships. If we grant, we have identified another area for collaboration a series of Zoom meetings. This has made it possible for pursue our plan to publish a collection of the colloquium on plant pathogen genomics involving several laboratories us to continue working on the project without significant presentations, that will further strengthen the working in France. PhD student from Berkeley who was scheduled disruption. We already had two such meetings and a Project #46-2019 relationships. to visit Montpellier will present his research findings by third one is planned in April. The meetings proved very zoom on May 27th. We are still planning the visits and successful, and were characterized by a large and active 5) Will this project result in a publication? (Indicate bioinformatics analyses and have requested a 6 month to 1 UC PI: Elizabeth Abel (English, UC Berkeley) form of publication, if possible.) participation of graduate students from the two groups. France pi: Claire Davison (Université Sorbonne year extension due to COVID19. We had planned for a second —publication-oriented— Nouvelle, Paris) We have been invited to guest edit a special issue of the workshop in June 2020, but we are currently considering PROJECT TITLE: Sound Waves: Resonances of Virginia 4) Comment on the collaborative nature of the moving it to September due to the COVID-19 pandemic. journal Women’s Studies devoted to the colloquium project. Highlight aspects of the project that have Woolf presentations. We plan to defer that project until after the MONTH/YEAR OF AWARD ACTIVATION: July 2019 fostered continuing relationships between French 2) Indicate how much money has been spent to date. second installment of the colloquium. institutions and UC campuses. How much do you anticipate spending? 1) What is the current status of the project? What has The project is connected to collaborations of the project been achieved? How does this relate to the original About $7k have been spent so far, the rest of the grant projected timeline? partners with other researchers, and it is anticipated that will cover outstanding research costs and part of the cost these networks will partially join at a more advanced stage of the second workshop (co-sponsored by CSTMS), for a Our colloquium on “Sound Waves: Resonances of of the project. A first result in this sense is a connection total of about $6k. established between the group of Prof Krasileva and Virginia Woolf” convened as planned at the University of INRAE researchers in Montpellier working on fungal California, Berkeley, on October 25-6, 2019. It generated population and comparative genomics. lively discussion and interest among the participants, 3) What remains to be done for this project? When will which included four French scholars of Virginia Woolf. The the project be completed? 56 | France-Berkeley Fund Annual Report 2019-20 Annual Report 2019-20 France-Berkeley Fund | 57 INTERIM REPORTS INTERIM REPORTS 2019-20 2019-20

the project in other ways, including, possibly, facilitating Swiss and other nationalities. Bidart has already developed level and US county-level lifetables series will be made work between Marseilles and Toulouse; supporting interest in this book at a major university press. Given the freely available to all, following the model of the Human Project #50-2019 research assistance for the project here; perhaps assisting volume of work, it is likely that a couple of journal articles Mortality Dataset. travel to the ASA. As you can imagine, everything has will be spun off as well. All necessary demographic data (birth, death, UC PI: Claude Fischer (Sociology, UC Berkeley) moved into improvisation. and population counts by sex, age and geography – US France pi: Guillaume Favre (Université Jean Jaures, counties and French départements) have been collected, Toulouse) 3) What remains to be done for this project? When will Project #54-2019 prepared and formatted in a consistent manner. PROJECT TITLE: Evolutions of Personal Networks Across the project be completed? Several components of the project have been Time UC PI: Magali Barbieri (Demography, UC Berkeley) presented at the International Workshop on Subnational MONTH/YEAR OF AWARD ACTIVATION: December 2019 The final sets of data analyses for the study of France pi: Hippolyte D’Albis (Paris School of Lifetables hosted by the Australian National University “partnering” are almost all done. A framework for the Economics) Department of Demography on October 15-17, 20191 1) What is the current status of the project? What has chapter on partnering’s effects on networks has been PROJECT TITLE: Geographic variations in the length of (“The United States Mortality DataBase: Current Status been achieved? How does this relate to the original drafted. An actual draft chapter should be soon completed life: Comparing France and the United States and Future Projects”, Celeste Winant and Magali Barbieri, projected timeline? once Bidart recovers from COVID-19. Then, this will serve MONTH/YEAR OF AWARD ACTIVATION: November 2019 Session 1; “A Bayesian Model to Estimate Mortality in as a template for future chapters. Small Populations”, Celeste Winant and Monica Alexander, The project was severely disrupted by the coronavirus On completion timing: Except, of course, for the 1) What is the current status of the project? What has Session 3; “The Evolving Geography of US Mortality. A crisis. Favre and Bidart had been in Berkeley several weeks Berkeley conference of March 16 to March 20 which was been achieved? How does this relate to the original State-level analysis of converging/diverging trends in the successfully collaborating with Fischer and preparing a eliminated by the coronavirus emergency, the immediate projected timeline? length of life”, Magali Barbieri and Florian Bonnet, Session week-long mini-conference that would include Michel product—a draft chapter—should be done before June 1. 6; and “Methodological issues in constructing a French Grosetti from Toulouse and a few UC Berkeley-associated The larger project to which this FBF grant has contributed, The practical purpose of the project is to construct two HMD for the 20th Century”, Florian Bonnet, Session 7). colleagues. The conference was to start on March 16, a multinational comparative book on the lifecycle and comparable databases of mortality indicators at the local The construction of an online database to the day that the sheltering-in-place rule went into effect. personal networks, has been set back months. (For level for France and for the United States using standard host the French data series by départements is under- Bidart and Fauvre had already been forced to hurriedly example, some collaborators were to meet in Paris in demographic and statistical methods. Its end goal is to way. The database will be hosted by the Paris School of return early to France the day before because entry to June., but that seems highly unlikely.) But, the larger investigate the contribution of geographic variations in Economics (under the leadership of Hippolyte d’Albis). An France was about to be closed down. (Grosetti returned project should be completed by mid-2022. mortality in diverging life expectancy trends between application has been developed by Denys Dukhovnov to to France shortly after he arrived.) Bidart came down with the two countries. Around 1980, the expected length of facilitate vizualisation of the results by database users. The the virus a week after returning to Marseilles. 4) Comment on the collaborative nature of the life was very close in the two countries (with a 0.3 years application has already been deployed on the US database Prior to the crisis, Bidart, Fauvre, and Fischer had project. Highlight aspects of the project that have advantage for France). In 2016, the length of life for the (see https://shiny.demog.berkeley.edu/hmd/USHMD_ made considerable progress in harmonizing the analysis fostered continuing relationships between French average American was 3.5 years shorter than for his MapApp/ ) and its implementation for the French database of the two sets of French and one set of American data institutions and UC campuses. French counterpart. In an effort to better understand this is in progress (see Figure 1 for screenshot of prototype) to enable solid contrasts and comparisons, focusing distressing trend, historical series of mortality indicators on the question of how moving through the stages of The unfortunate disruption aside, the in-person are to be prepared for all US states and counties for the 2) Indicate how much money has been spent to date. acquiring a long-term life partner affects individuals’ collaboration between the French scholars and Berkeley- period from 1959 to 2018 and 1982 to 2018, respectively, How much do you anticipate spending? personal networks. This exercise will make expansions of based scholars has been fruitful. Hours were spent in side- and for all French départements for the period from 1901 the French-American analyses to other lifecycle transitions by-side work. And it will certainly continue. Fischer will to 2015. Once these data series have been prepared, the See below. (graduating, parenting, retiring, etc.) much smoother. continue to work with Bidart, Fauvre, Grosetti, and others. project team will collaborate to study how the changing Progress was slowed but not halted by the disruption and As important, connections have been made between the geography of US mortality has slowed down progress in 3) What remains to be done for this project? When will by Bidart’s illness; it continues by long distance, albeit less French scholars and other Berkeley-origin researchers. For survival relative to France. Expected project outcomes: the project be completed? efficiently. We are behind schedule but still working. The example, Fauvre has started working with Eric Giannella (a include hope is that we may manage face-to-face meetings later UC Phd., student of Fischer) on one comparative project 1. Methods for constructing lifetable series in small The activities planned for the rest of the grant period are: in the year if the meetings of the American Sociological and with Keunbok Lee (UC Phd., student of Fischer; now populations: this part of the project will mostly benefit - To finish all US and French data series (i.e. lifetables at Association scheduled for August in San Francisco post-doc at UCLA) on another. Stephanie Child (recent the French team as they will gain inside knowledge of the the US county and French départements levels) estimated proceed. post-doc on Fischer’s UCNets project, now also affiliated methods implemented to construct mortality series in the with the Bayesian model. Note that the project has been with UCSF) has connected with Bidart. And so on. US counties and receive support from the HMD team to severely disrupted due to the shelter-in-place orders 2) Indicate how much money has been spent to date. adjust these methods to the French departments. and other covid-19 related interventions implemented How much do you anticipate spending? 5) Will this project result in a publication? (Indicate 2. Methods for analyzing geographic disparities in France and in the United States. More specifically: form of publication, if possible.) in mortality: this part of the project will mostly benefit the UC Berkeley team had to carry out most of its work The bulk of the funds have been spent to meet the high the American team as they will be able to implement the within the UC Berkeley Research Data Center (RDC), a expense of housing in Berkeley (despite sharing of housing Most directly, the work done with FBF support will methods used in the French case to investigate changes in protected facility overseen by the US Census Bureau, by Bidart and Fauvre). Even though they had to leave contribute to an ongoing multi-author, multinational book geographic variations in mortality in the United States. because of the restricted nature of all US vital statistics early, commitments had been made to pay for the housing on life events and personal networks that was initiated at 3. Construction of lifetable series to be published and census data necessary for the project; closure of all through May. Those funds are spent or encumbered. That a Marseilles workshop in May, 2019, and which included in open-access: the scientific community at large will US RDCs (including the one at UC Berkeley) means that leaves $1,100. We would like to use those funds to advance a number of French researchers, but also Spanish, Israeli, benefit from this project as the French department- the construction of county-level mortality series had to be 58 | France-Berkeley Fund Annual Report 2019-20 Annual Report 2019-20 France-Berkeley Fund | 59 INTERIM REPORTS INTERIM REPORTS 2019-20 2019-20

interrupted until the RDCs reopen. (at usa.mortality.org) and publish the French database Mediterranean-climate catchments developed by the 205), which will conduct analyses on the Montecito case, Both the 2020 meeting of the Population on a dedicated website (hosted by the Paris School of University of Avignon (RuiCell). We have also analyzed the including developing better land management policies in Association of America and the 2020 European Population Economics). In addition, we will prepare a second paper role that flood risk maps (developed from the models) can debris-flow prone landscapes. Conference have been canceled, so the project team will measuring the contribution of widening geographic play in land use planning and emergency management. be unable to present the initial results of the project to the disparities in the length of life in the US to the divergence Berkeley Workshop (5-7 February 2020): The 4) Comment on the collaborative nature of the international research community; we are hoping to be in mortality between the US and France over the 1980- Berkeley workshop included two participants from project. Highlight aspects of the project that have again accepted for an oral presentation at the 2021 annual 2018 period. France, Professors Johnny Douvinet, and Renaud Vidal fostered continuing relationships between French meeting of the Population Association of America (to (engineer working at a regional enterprise called Atrisc), institutions and UC campuses. be held in Saint Louis, Missouri, on May 5-8) and we will along with Berkeley co-PIs Serra-Llobet and Radke, other investigate other venues in due time. Berkeley faculty from the natural and social sciences and This project has created a long-term transdisciplinary Florian Bonnet’s extended visit in Berkeley in April- engineering, researchers from the CCRM (UC Berkeley team involving physical and social scientists from Berkeley June 2020 had to be postponed due to the current travel Project #58-2019 Center for Catastrophic Risk Management), graduate and different French institutions, all of whom seek to restrictions. A large part of the funding requested from students and post-doctoral scholars, and practitioners develop new ways to understand and manage floods the FBF was to cover his travel and living expenses while UC PI: Anna Serra-Llobet and John Radke (Institute of involved in land-use and flood management. and debris flows. With the collaborations and synergies in Berkeley. We are hoping that Florian can visit once the International Studies, UC Berkeley) established under this grant, we will to seek opportunities epidemiologic situation has improved (though note that France pi: Johnny Douvinet (Université d´Avignon et 2) Indicate how much money has been spent to date. to pursue larger grant proposals to funding agencies because of his teaching duties, it might be difficult for him des Pays du Vaucluse) How much do you anticipate spending? such as the NSF (e.g., the Human Disasters and the Built to visit before the Spring of 2021). PROJECT TITLE: From epic wildfires to epic flash- Environment call) and/OR the European Research Council floods: Rethinking flood risk management in an era of From the total FBF grant of $10,950.00, to date $5,694.83 (e.g., the Consolidator Grants) or FP9. Consequently, the project team is requesting a one-year extremes has been spent ($2642.06 in the Berkeley workshop of no-cost extension to the France-Berkeley Fund. As soon as MONTH/YEAR OF AWARD ACTIVATION: October 2019 February 2020, $893.37 in the Montecito Field Trip of 5) Will this project result in a publication? (Indicate we know when these activities can resume, we will provide November 2019, and $2159.40 for the plane tickets for form of publication, if possible.) a revised timeline for the project. 1) What is the current status of the project? What has the Avignon workshop of April 2020). We anticipate been achieved? How does this relate to the original spending the balance on the Avignon Workshop (expenses We plan to submit 2 papers with final results in July 2020. 4) Comment on the collaborative nature of the projected timeline? beyond the flights already purchased, local travel and The first paper will be related to the model created to project. Highlight aspects of the project that have accommodation in Avignon, appx $1600), a follow-up define the hydrologic susceptibility aggravation due to the fostered continuing relationships between French Field Trip to Montecito (7-10 Nov 2019): In order to field trip to Montecito to conduct interviews and to work wildfire and the second will be oriented to the comparison institutions and UC campuses. gather information from the 2018 Montecito debris flow directly with potential collaborators at UC Santa Barbara between the US and France, on how they manage event, Dr. Serra-Llobet has analyzed hydrologic data, and (appx $1360), and publication fees ($2100). As per the compound hazards under the current policy framework. The Bayesian model developed by the University of conducted field visits and structured interviews to better attached budget, we should be slightly under our original Intended outlet for the US-France comparison: California, Berkeley project team has been tested on understand the land-use and emergency response aspects budget at the end of the project. Environmental Research Letters, an open-access journal. the US data and work is under way to adapt it to the of the 2018 Montecito event. The interviewees included: French data. Work on applying the methods used by the Jonathan (Yonni) Schwartz, US Forest Service (Los Padres 3) What remains to be done for this project? When will French team to analyze trends in geographic disparities National Forest), Professor Ed Keller, UC Santa Barbara, Dr. the project be completed? in mortality to the US setting was initiated when Denys Mark Capelli, NOAA, and Mr. Joseph Dargel, Supervising Dukhovnov and Magali Barbieri came to spend a week Planner, Santa Barbara County, Office of Planning and Avignon Workshop (6-8 April 2020): The next step for Project #62-2019 in Paris in December 2019 to meet with Florian Bonnet; Development. Field visits to affected areas along the this project is to organize a workshop in Avignon (6-8 this work led to the writing of a paper which has been Montecito and San Ysidro creeks were conducted with April 2020) which will include three participants from UC PI: Edgar Knobloch (Physics, UC Berkeley) accepted for presentation at the 2020 annual meeting Professor Ed Keller, UC Santa Barbara and Dr. Mark Capelli Berkeley (Drs Serra-Llobet and Radke, and PhD student France pi: Benjamin Favier (CNRS / Aix-Marseille of the Population Association of America (Washington NOAA. A detailed itinerary for the interviews and field trip Sara Lindbergh), the French co-PI (Dr Douvinet), as well Université) D.C., April 23-25) and at the 2020 European Population is attached. Through this visit, Dr Serra-Llobet established as Dr Freddy Vinet, Professor of Risk and Catastrophic PROJECT TITLE: Large-scale structures in anisotropic Conference (Padova, Italy, June 24-27). The paper is titled initial collaboration with researchers at UC Santa Barbara, Management (University of Montpellier), Dr Daniel turbulence “Continuity and change in the geography of US longevity” which can be further developed. Delahaye, Professor of Physical Geography (University of MONTH/YEAR OF AWARD ACTIVATION: July 2019 (see Appendix 1 for a short summary). Dr. Douvinet was a visiting scholar at the Caen Normandy), practitioners involved in land-use and UC Berkeley Institute of International Studies (IIS), flood management, and junior scholars. 1) What is the current status of the project? What has collaborating with the Center of Catastrophic Risk Montecito Field Trip and Interviews (15-20 April been achieved? How does this relate to the original 5) Will this project result in a publication? (Indicate Management (CCRM), from Jan 27 to Feb 8, 2020. 2020): A follow-up field trip to work with collaborators projected timeline? form of publication, if possible.) During his visit, Dr. Douvinet, Dr. Vidal, Dr Radke, and Dr. at UC Santa Barbara, visit additional sites affected by Serra-Llobet analyzed hydrologic data and worked on the debris flows, and to interview key actors, including The PIs met in July 2019 and again in January 2020 We intend to complete the first paper while Florian the application of new models to improve flood-alert scientists in the US Geological Survey office that issued when Knobloch traveled to France. During these visits Bonnet is visiting Berkeley and submit to a peer- systems, drawing upon both a high-resolution fire model the debris-flow warning, and Santa Barbara County staff. the PIs studied the properties of wall states in rapidly reviewed scientific journal. We also aim to publish the developed at UC Berkeley by John Radke (Radke et al. During part of this trip, Serra-Llobet will coordinate rotating convection - the first state that forms when US county-level mortality series on the USMDB website 2018) and a hydrological model for flash-floods in small with the Environmental Planning Studio class (LandArch the conduction state loses stability. In particular, they 60 | France-Berkeley Fund Annual Report 2019-20 Annual Report 2019-20 France-Berkeley Fund | 61 INTERIM REPORTS INTERIM REPORTS 2019-20 2019-20

established the robustness of highly nonlinear wall states levels. The images below show the results of one of the and at a Pacific Earthquake Engineering Center (PEER) in this system to (i) presence of turbulence in the bulk, 4) Comment on the collaborative nature of the scans showing the 3-D grain fabric. workshop in Berkeley in January 2020. A paper to be and (ii) dramatic changes to the shape of the domain, project. Highlight aspects of the project that have Overall, the triaxial tests were very successful submitted to an international journal is in preparation. for example, by inserting a radial barrier into a cylindrical fostered continuing relationships between French and represent the first time that undisturbed samples of container. In both cases the wall mode continues to institutions and UC campuses. sandy deposits were tested and at the same time imaged precess in a retrograde sense along the boundary of in 3-D XRCT. We spent the period from August to January the domain. The PIs relate these observations to recent The collaboration between PIs Knobloch and Favier is off to process and interpret the data. This step in the project observations of boundary zonal flows in high Rayleigh to an excellent start. The PIs complement each other well took longer than we expected because the scans showed number experiments by two distinct experimental and plan to continue collaborating beyond the one year that the fabric of the samples was not simple. We are in groups and suggest that these states behave like funded by the France-Berkeley Fund, focusing on systems the process of writing papers describing the results of the topologically protected edge states familiar from exhibiting highly anisotropic turbulence. experiments. studies of two-dimensional semiconductors. The PIs are attempting to support this suggestion by performing 5) Will this project result in a publication? (Indicate 2) Indicate how much money has been spent to date. additional simulations and undertaking new theoretical form of publication, if possible.) How much do you anticipate spending? investigations. The PIs submitted their results as a Rapid Communication to the Journal of Fluid Mechanics, the The details of the first paper arising from this The amount spent to date is $4994 from a budget of premier journal in the field, at the end of February. The collaboration may be found in: arXiv:2002.12802 $10950. The expenditures to date consisted of travel and details of the work may be found in: arXiv:2002.12802 the cost of experimental facilities at Laboratoire 3SR (Sols, PI Favier had planned a 2-week visit to Berkeley Solides, Structures, Risques) at the Université Grenoble in April but that visit has had to be cancelled. Likewise, Alpes in Grenoble. We were planning for another round of PI Knobloch’s visit to Marseille in June is unlikely to take Project #63-2019 testing that would have taken place in late May of this year. place under current travel restrictions. The PIs hope that Unfortunately, that timetable is not possible now. That the Berkeley-France Fund will take the current situation UC PI: Nicholas Sitar (Civil & Environmental effort would have used majority of the remaining funds. into consideration when the PIs request an extension Engineering, UC Berkeley) beyond the current end-date of 07/13/2020. France pi: Cino Viggiani (Université Grenoble Alpes) 3) What remains to be done for this project? When will PROJECT TITLE: Characterization of Depositional Fabric the project be completed? 2) Indicate how much money has been spent to date. of Sands Using 3-D X-Ray Computed Tomography (3-D How much do you anticipate spending? XRCT) At this point we have not been able to perform the second MONTH/YEAR OF AWARD ACTIVATION: July 2019 set of experiments which we hoped to conclude in May To-date the PIs have spent approximately $7000 (two of 2020. Given the uncertainty about travel we cannot trips to France by PI Knobloch and a presentation by PI 1) What is the current status of the project? What has estimate a possible future date for these experiments. Knobloch of the PIs’ results at the APS Division of Fluid been achieved? How does this relate to the original However, we are in the process of writing up the results Dynamics in Seattle in November) leaving approximately projected timeline? for publication which, while sparse, can stand alone. $5000 for the two remaining planned visits. As indicated the PIs will be requesting an extension of the project The goal of the project has been to use 3-D X-Ray 4) Comment on the collaborative nature of the in order to undertake these visits as soon as travel Computed Tomography (3-D XRCT) device at the project. Highlight aspects of the project that have restrictions ease. The PIs have found that in-person Laboratoire 3SR - Sols, Solides, Structures, Risques at fostered continuing relationships between French discussions are invaluable in formulating key questions the Universite Grenoble Alpes to study the depositional institutions and UC campuses. that have resulted in substantial progress. structure of natural sands and the effect of the fabric on the strength and stress-strain behavior of these This project provided a unique opportunity for us to 3) What remains to be done for this project? When will materials. The original plan called for two discrete sets interact to perform a novel set of experiments which the project be completed? of experiments roughly 6-8 months apart. The first set of are only the beginning of further collaboration at all experiments was successfully concluded in July 2019. levels. Specifically, there are further opportunities for As indicated the PIs expect a delay in the completion of The main challenge in this effort has been in being more sophisticated experiments on a broader range of the project on account of current travel restrictions. They able to obtain very small undisturbed samples that fit into materials and there are opportunities to develop more are currently focusing on two topics: understanding the the target chamber of the X-Ray scanner. We successfully sophisticated visualization and modeling tools. We expect origin of the observed robustness of the wall states in obtained undisturbed samples of natural sandy shoal that this cooperation will continue with reciprocal visits as rapidly rotating turbulent convection, and the origin of deposits and undisturbed samples of hydraulic fill material we enhance the experimental facilities at both institutions. large scale vortex structures that are observed to develop from Treasure Island in the San Francisco Bay. We then 5) Will this project result in a publication? (Indicate in highly anisotropic turbulence, including rapidly rotating performed tests on four different samples, two from form of publication, if possible.) turbulent convection. Both goals are major research hydraulic fill and two from natural shoal deposit. The tests efforts and are expected to extend beyond the end date of were performed at different confining pressures so that The preliminary results of this work were presented at an the project. we could observe the material behavior at different stress NSF workshop in Christchurch, NZ, in September 2019 62 | France-Berkeley Fund Annual Report 2019-20 Annual Report 2019-20 France-Berkeley Fund | 63 SUPPORT OUR WORK

The project has deepened The France-Berkeley Fund has been fantastic support our working relationship and for the initiation of this research trajectory. Without also enhanced or established it, this project could not have proceeded in this relationships for all who collaborative fashion. It has advanced the research "have participated in it. We are "career of a Berkeley junior faculty member, provided valuable IMAGE CREDITS certain that these connections will training for a Berkeley PhD, and led to an academic research bear fruit in other contexts in the position for a recent French PhD. These collaborative Cover: Campanile Blueprint // Courtesy of UC Berkeley Office of Public Affairs years ahead. relationships will be sustained into the future. p. 13 Eric Goubault // by Jeremy Barande p. 14 Aurèle Piazza // by Noemie Guitter - TODD HICKEY (Classics, UC - NICHOLAS SWANSON-HYSELL (Earth & Planetary Sciences, p. 14 John Kuriyan // by June Vega Photography Berkeley) and JEAN-LUC FOURNET UC Berkeley) and YVES GODDÉRIS (Observatoire Midi-Pyrénées, p. 15 Edward Frenkel // by Emily Scher (Collège de France / EPHE) CNRS / Université Toulouse) p. 15 David Hernandez // by Archives of the Mathematisches Forschungsinstitut Oberwolfach p. 16 Timothy Hampton // by Eric Kotila p. 17 David Whitney // by Cristina Ghirardo This has been an invaluable experience for the junior researchers involved and it has directly facilitated the establishment of larger-reach projects between Lyon and Berkeley. " ACKNOWLEDGEMENTS - MARY FIRESTONE (Environmental Science, Policy & Management, UC Berkeley) and GRAEME NICOL (Laboratoire Ampère, Université de Lyon) The France-Berkeley Fund gratefully acknowledges the partners and collaborators whose efforts and support are crucial to our program. In particular, we thank:

- Dean Anthony Cascardi (UC Berkeley Division of Arts & Humanities) and Professor Andrew Garrett (Department For the past 25 years, the France-Berkeley Fund has advanced innovative research and international of Linguistics), for committing valuable financial support through the Diebold Fund for two projects on the topic of exchange across the humanities and sciences. Help ampllify our work by making a gift to our grant language usage and translation, language history, and linguistic change - Yves Frénot and the Office of Science and Technology for supporting the Bayen/Goubault collaboration on fund, Gifts to the FBF go directly to help sustain cutting-edge collaborations that bring together faculty, transportation engineering researchers, and junior scholars from UC Berkeley and institutions throughout France. - Patricia Geltz, Elise Binet Mahé, Corrine Perret, and their colleagues at the French Ministry of Higher Education, To learn more and make a gift, visit Research and Innovation - Vincent Michelot (Attaché for Higher Education, Embassy of France in the United States) - Kimberly Carl (Director, IT Systems and Services, UC Berkeley Office of the Vice Chancellor for Research) fbf.berkeley.edu - Zahra Rezapour (Financial Analyst, UC Berkeley Office of the Vice Chancellor for Research) - Gia White (Administrative Director, Institute of European Studies, UC Berkeley) - Julie de Vaulx (Undergraduate Research Apprentice)

64 | France-Berkeley Fund Annual Report 2019-20 Annual Report 2019-20 France-Berkeley Fund | 65 FRANCE-BERKELEY FUND University of California, Berkeley

66 | France-Berkeley Fund Annual Report 2019-20 fbf.berkeley.edu