Anti-CATSPER3 Polyclonal Antibody Cat: K008389P Summary:

【Product name】: Anti-CATSPER3 antibody 【Source】: Rabbit

【Isotype】: IgG 【Species reactivity】: Human Mouse

【Swiss Prot】: Q86XQ3 【 ID】: 347732

【Calculated】: MW:46kDa 【Observed】: MW:46kDa

【Purification】: Affinity purification

【Tested applications】: WB

【Recommended dilution】: WB 1:500-2000.

【WB Positive sample】: Mouse testis,Mouse brain,Mouse kidney,Mouse lung,Jurkat,A549

【Subcellular location】: Cell membrane

【Immunogen】: Recombinant of human CATSPER3

【Storage】: Shipped at 4°C. Upon delivery aliquot and store at -20°C Background: CatSpers (cation channel, sperm associated ) are ion transport proteins located on the surface of sperm cells in the principal piece of the sperm tail. CatSpers are vital to sperm motility, fertilization and cAMP-mediated calcium influx in sperm. There are four CatSper proteins in mammalian sperm, namely CatSper (or CatSper1), CatSper2, CatSper3 and CatSper4. CatSper proteins contain a single, six-transmembrane-spanning segment and exhibit the voltage-dependent Ca2+ channel four-repeat structure. CatSper proteins are believed to assemble into a heterotetrameric complex, forming an alkalinization-activated Ca2+-selective channel. Mutations in any of the encoding CatSper family proteins can result in male infertility. CatSper3 plays an important role in the hyperactivated motility of sperm cells, a process that is required in the preparation of sperm for fertilization.

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Western blot analysis with CATSPER3 antibody diluted at 1:1000;Lane: Mouse testis,Mouse brain,Mouse kidney, Mouse lung,Jurkat,A549

Immunohistochemistry of paraffin-embedded Human thyroid cancer with BGN antibody diluted at 1:50

Sales:[email protected] For research purposes only. Tech:[email protected] Please visit www.solarbio.com for a more product information