Product Datasheet
MAD2L1 Antibody
Catalog No: #35330
Package Size: #35330-1 50ul #35330-2 100ul Orders: [email protected] Support: [email protected]
Description
Product Name MAD2L1 Antibody
Host Species Rabbit
Clonality Polyclonal
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific
immunogen.
Applications WB
Species Reactivity Hu
Specificity The antibody detects endogenous levels of total MAD2L1 protein.
Immunogen Type Peptide
Immunogen Description Synthesized peptide derived from internal of human MAD2L1.
Target Name MAD2L1
Other Names Mitotic spindle assembly checkpoint protein MAD2A; HsMAD2; Mitotic arrest deficient 2-like protein 1;
MAD2-like protein 1; MAD2L1
Accession No. Swiss-Prot: Q13257NCBI Gene ID: 4085
SDS-PAGE MW 25kd
Concentration 1.0mg/ml
Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide
and 50% glycerol.
Storage Store at -20°C
Application Details
Western blotting: 1:500~1:3000
Images
Western blot analysis of extracts from A549 cells, using MAD2L1 antibody #35330.
Address: 8400 Baltimore Ave., Suite 302, College Park, MD 20740, USA http://www.sabbiotech.com 1 Background
Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Required for the execution of the mitotic checkpoint which monitors the process of kinetochore-spindle attachment and inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate. Li Y., Science 274:246-248(1996). Gemma A., Lung Cancer 32:289-295(2001). Jin D.-Y., Submitted (JUL-1995) to the EMBL/GenBank/DDBJ databases.
Note: This product is for in vitro research use only and is not intended for use in humans or animals.
Address: 8400 Baltimore Ave., Suite 302, College Park, MD 20740, USA http://www.sabbiotech.com 2