Product Datasheet

MAD2L1 Antibody

Catalog No: #35330

Package Size: #35330-1 50ul #35330-2 100ul Orders: [email protected] Support: [email protected]

Description

Product Name MAD2L1 Antibody

Host Species Rabbit

Clonality Polyclonal

Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific

immunogen.

Applications WB

Species Reactivity Hu

Specificity The antibody detects endogenous levels of total MAD2L1 .

Immunogen Type Peptide

Immunogen Description Synthesized peptide derived from internal of human MAD2L1.

Target Name MAD2L1

Other Names Mitotic spindle assembly checkpoint protein MAD2A; HsMAD2; Mitotic arrest deficient 2-like protein 1;

MAD2-like protein 1; MAD2L1

Accession No. Swiss-Prot: Q13257NCBI ID: 4085

SDS-PAGE MW 25kd

Concentration 1.0mg/ml

Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide

and 50% glycerol.

Storage Store at -20°C

Application Details

Western blotting: 1:500~1:3000

Images

Western blot analysis of extracts from A549 cells, using MAD2L1 antibody #35330.

Address: 8400 Baltimore Ave., Suite 302, College Park, MD 20740, USA http://www.sabbiotech.com 1 Background

Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all are properly aligned at the metaphase plate. Required for the execution of the mitotic checkpoint which monitors the process of -spindle attachment and inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate. Li Y., Science 274:246-248(1996). Gemma A., Lung Cancer 32:289-295(2001). Jin D.-Y., Submitted (JUL-1995) to the EMBL/GenBank/DDBJ databases.

Note: This product is for in vitro research use only and is not intended for use in humans or animals.

Address: 8400 Baltimore Ave., Suite 302, College Park, MD 20740, USA http://www.sabbiotech.com 2