Supplementary Table S1 (Mitchell et al.)

fold Symbol Gene Name change p-value AR Androgen -1.20 0.922 BAD BCL2 Associated Death Promoter 1.47 0.471 BAG1 BCL2 associated anthogene 2.66 0.144 BCL2 BCL2 2.36 0.419 BCL2L2 BCL2-like 2 -2.55 0.432 C3 Cytochrome C3 hydrogenase -2.27 0.129 CCNA1 Cyclin A1 1.50 0.513 CCNA2 Cyclin A2 3.46 0.190 CCND1 Cyclin D1 -1.39 0.538 CCNE1 Cyclin E1 1.50 0.614 CD44 CD44 -1.67 0.515 CDH1 E-Cadherin 21.77 0.020 CDKN1A Cyclin Dependent Kinase Inhibitor 1A -p21 1.70 0.639 CDKN1B Cyclin Dependent Kinase Inhibitor 1B -p27 1.88 0.488 CDKN2A Cyclin Dependent Kinase Inhibitor 2A -p16 -14.93 0.044 CLDN7 Claudin 7 2.03 0.608 CLU Clusterin -1.00 1.000 COL6A1 Collagen Type 1V alpha 1 -1.30 0.306 CTNNB1 Beta-catenin -1.10 0.844 CTSB Cathepsin B -1.01 0.987 CTSD Cathepsin D 2.85 0.263 CYP19A1 Aromatase 4.69 0.149 DLC1 Deleted in Cancer 1--tumor suppressor 2.21 0.402 EGFR Epidermal Receptor 3.77 0.175 ERBB2 Her2/Neu 3.12 0.145 ESR1 Estrogen receptor Alpha -16.37 0.009 ESR2 Estrogen receptor Beta 1.44 0.655 FAS -1.97 0.018 FASLG Fas -2.03 0.446 FGF1 Fibroblast growth factor 1 -1.51 0.434 FLRT1 Leucine Rich Transmembrane 1 2.31 0.513 FOSL1 Fos-like antigen 1 1.27 0.617 GABRP Gamma-aminobutyric acid (GABA) A Receptor 1.52 0.701 GATA3 GATA Binding Protein 3 4.80 0.039 GNAS GNAS 1.05 0.975 GSN Gelsolin 1.12 0.877 HMGB1 High-mobility group box-1 1.00 0.997 HSPB1 HSP27 1.72 0.556 ID2 Inhibitor of DNA Binding 2 -1.01 0.975 IGFBP2 Insulin-Like Growth Factor-Binding Protein 2 -9.80 0.053 IL2RA Receptor 2 Alpha -3.87 0.426 IL6 -3.47 0.103 IL6R Interleukin 6 Receptor -2.05 0.226 IL6ST /CD130 2.30 0.310 ITGA6 Alpha 6 -4.11 0.216

Supplementary Table 1, continued (Mitchell et al.)

ITGB4 1.80 0.526 JUN c-Jun -1.05 0.936 KIT CD117 1.17 0.875 KLF5 Kruppel-like factor 5 1.07 0.886 KLK5 Kallikrein-related peptidase 5 -6.58 0.218 KRT18 Keratin 18 2.18 0.347 KRT19 Keratin 19 -1.07 0.940 MAP2K7 Mitogen Activated protein kinase-kinase 7 -1.84 0.547 MKI67 Ki-67 -1.23 0.765 MT3 Metallothionectin-III 3.52 0.034 MUC1 Mucin 1 2.23 0.110 NFYB Nuclear Y, beta -1.33 0.388 NGF Nerve Growth Factor -1.06 0.945 NGFR Nerve Growth Factor Receptor 2.87 0.281 NME1 Non-metastatic cells 1--thought to be a metastasis suppressor 1.50 0.497 PAPPA Pregnancy-associated Plasma Protein A -1.68 0.442 PGR Progesterone Receptor -2.85 0.395 PLAU Plasminogen activator, urokinase -1.55 0.286 PTEN Phosphatase and Tensin Homolog 1.66 0.392 PTGS2 Cyclooxygenase 2 -74.18 0.001 RAC2 RAC2 -1.80 0.199 RPL27 ribosomal protein l27 1.22 0.656 SCGB1D2 secreteglobin, family 1D, member 2 -1.11 0.930 SCGB2A1 secreteglobin, family 2A, member 1 2.97 0.358 SERPINA3 Alpha 1-antichymotrypsin 1.88 0.560 SERPINB5 Maspin 2.40 0.582 SERPINE1 PAI-1 1.13 0.878 SLC7A5 Solute Carrier Family 7, Subfamily A, Isoform 5 1.38 0.672 SPRR1B Small-proline-rcih protein 1B, cornifin 2.45 0.418 STC2 Stanniocalcin 2 -1.27 0.711 TFF1 Trefoil Factor 1 2.47 0.465 TGFA TGF alpha -3.10 0.405 THBS1 1 -1.94 0.283 THBS2 Thrombospondin 2 1.09 0.882 TIE1 Kinase with immunoglobulin-like and EGF-like domains 1 3.60 0.210 TNFAIP2 , alpha induced protein 2 2.87 0.190 TOP2A Topoisomerase II, alpha 2.75 0.283 TP53 Tumor Protein p53 -1.62 0.597 VEGFA Vascular Endothelial Growth Factor A 1.12 0.925