Anti-IMMT Monoclonal Antibody, Clone FQS9850 (DCABH-3312) This Product Is for Research Use Only and Is Not Intended for Diagnostic Use

Anti-IMMT monoclonal antibody, clone FQS9850 (DCABH-3312) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Product Overview Rabbit monoclonal to Mitofilin

Antigen Description The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group D2. This protein is monoubiquinated in response to DNA damage, resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair. Alternative splicing results in two transcript variants encoding different isoforms.

Immunogen Synthetic peptide corresponding to amino acids in Human Mitofilin (UniProt ID: Q16891).

Isotype IgG

Source/Host Rabbit

Species Reactivity Human

Clone FQS9850

Purity Tissue culture supernatant

Conjugate Unconjugated

Applications WB, IHC-P, ICC/IF, Flow Cyt

Positive Control Human fetal heart and Human fetal muscle tissue lysates, HeLa, A673, and Saos 2 cell lysates; Human colon and Human testis tissues; HeLa cells

Format Liquid

Size 100 μl

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Preservative 0.01% Sodium Azide

Storage Store at -20℃.

Ship Shipped at 4°C.

GENE INFORMATION

Gene Name IMMT inner membrane protein, mitochondrial [ Homo sapiens ]

Official Symbol IMMT

Synonyms IMMT; inner membrane protein, mitochondrial; inner membrane protein, mitochondrial (mitofilin); mitochondrial inner membrane protein; HMP; MINOS2; mitochondrial inner membrane organizing system 2; mitofilin; P87; P89; motor protein; proliferation-inducing

Entrez Gene ID 10989

Protein Refseq NP_001093639

UniProt ID Q16891

Chromosome Location 2p11.2

Function protein binding;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]