Anti-P2RY4 monoclonal antibody (DCABH-12762) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Antigen Description The product of this belongs to the family of G- coupled receptors. This family has several subtypes with different pharmacological selectivity, which overlaps in some cases, for various and . This receptor is responsive to uridine nucleotides, partially responsive to ATP, and not responsive to ADP.

Immunogen A synthetic peptide of human P2RY4 is used for rabbit immunization.

Isotype IgG

Source/Host Rabbit

Species Reactivity Human

Purification Protein A

Conjugate Unconjugated

Applications Western Blot (Transfected lysate); ELISA

Size 1 ea

Buffer In 1x PBS, pH 7.4

Preservative None

Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

GENE INFORMATION

Gene Name P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4 [ Homo sapiens ]

Official Symbol P2RY4

Synonyms P2RY4; pyrimidinergic receptor P2Y, G-protein coupled, 4; P2Y purinoceptor 4; NRU; P2P; P2Y4; UNR; uridine receptor;

Entrez Gene ID 5030

Protein Refseq NP_002556

UniProt ID P51582

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved Location Xq13

Pathway Class A/1 (-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;

Function ATP binding; G-protein coupled purinergic nucleotide receptor activity; G-protein coupled receptor activity; UTP-activated nucleotide receptor activity; receptor activity; signal transducer activity; uridine nucleotide receptor activity;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved