04-06 November 2020

Virtual Conference Agenda

Start Finish Presenter details (GMT) (GMT) Wednesday, 4 November 2020

13:00 13:10 Welcome

Scientific Programme Committee: Susanna Dunachie, Nuffield Department of Medicine, UK Iruka Okeke, University of Ibadan, Nigeria Julian Parkhill, , UK Sharon Peacock, London School of Hygiene and Tropical Medicine, UK 13:10 13:50 Keynote 1 13:10 13:40 Quantifying Causes and Consequences of AMR Marc Lipsitch, Harvard, USA 13:40 13:50 Q&A Chair: Susanna Dunachie Moderator: Julian Parkhill Session 1: Genomic surveillance and : its role in detection, tracking and control of 13:50 15:30 antimicrobial resistance in LMIC Introduction to session Chair: Susanna Dunachie 13:50 14:10 Developing WGS capacity of the national AMR surveillance programme (ARSP) in the Philippines Sonia Sia, National research institute in tropical medicine, Philippines 14:10 14:30 Whole Genome Sequencing of Clinical Bacterial Isolates in Low-Resource Settings Happiness Kumburu, KCMC, Tanzania 14:30 14:50 How has revolutionized and antimicrobial resistance surveillance in Argentina and Latin America Josefina Campos, ANLIS, Argentina 14:50 15:00 Inside out: extensive transmission around, within and between two ICUs in Hanoi, Vietnam Leah Roberts, EMBL-EBI, UK 15:00 15:10 A high-resolution genomic analysis of Indian carbapenem resistant K.pneumoniae isolates and its association with capsular types and antimicrobial resistance Geetha Nagaraj, KIMS Medical College, India 15:10 15:30 Q&A Chair: Susanna Dunachie Moderator: Julian Parkhill 15:30 15:50 Break Session 2: Genomic evidence that informs the debate on the role of external and internal 15:50 environments in AMR Introduction to session Chair: Iruka Okeke 15:50 16:10 Antimicrobial resistance: Investigating the role of the healthcare environment Ginny Moore, Royal Free/PHE, UK Comparing gut microbiomes and resistomes in human and animal feces from rural versus urban Bangladesh using 16S 16:10 16:20 rRNA gene amplicon sequencing and long-read metagenomics Jenna Swarthout, Tufts University, USA Genetic contexts and locations of ESBL and AmpC ß-lactamase encoding genes in E. coli from pig and pig farm 16:20 16:30 workers in Vietnam are different and suggests limited transmission between the two hosts Yaovi Mahuton Gildas Hounmanou, University of Copenhagen, Denmark 16:30 16:40 The role of interspecies recombinations in the of multidrug-resistant pneumococci Josh Daeth,Imperial College London, UK 16:40 17:00 Q&A Chair: Iruka Okeke Moderator: Julian Parkhill 17:00 17:20 Break 17:20 18:40 Lightning talks and poster session (session 1)

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04-06 November 2020

Thursday, 5 November 2020 13:00 14:10 Session 3: Global burden of disease from drug-resistant : monitoring and evaluation Introduction to session Chair: Susanna Dunachie 13:00 13:10 The role of WGS for global AMR Surveillance: a WHO perspective Neil Woodford, GLASS/PHE, UK 13:10 13:30 AMR surveillance in LMICs: The pressing need for quality laboratory data and clinical relevance Paul Turner, COMRU, Cambodia 13:30 13:40 Global antibiotic consumption: a modelling study Annie Browne, Oxford University, UK 13:40 13:50 Comparison of de-duplication methods used by WHO Global Antimicrobial Resistance Surveillance System (GLASS) and Japan Nosocomial Infections Surveillance (JANIS) in the surveillance of antimicrobial resistance Koji Yahara, National Institute of Infectious Diseases, Japan 13:50 14:10 Q&A Chair: Susanna Dunachie Moderator: Iruka Okeke 14:10 14:40 Break 14:40 16:00 Session 4: Translating bacterial genomics and metagenomics into clinical practice Introduction to session Chair: Julian Parkhill 14:40 15:00 Nicole Stoesser, Univserity of Oxford, UK 15:00 15:20 Next generation sequencing: first diagnostic one-stop shop in personalised clinical John Rossen, University of Groningen, Netherlands 15:20 15:30 Genomic Characterization of a Rectal Colonization Outbreak of Carbapenem-resistant Acinetobacter baumannii in an Intensive Care Unit, Southwest Nigeria Erkison Odih, University of Ibadan, Nigeria 15:30 15:40 High-resolution genomic epidemiology of carbapenem-resistant Acinetobacter baumannii in a Chinese ICU Emma Doughty, , UK 15:40 16:00 Q&A Chair: Julian Parkhill Moderator: Susanna Dunachie 16:00 16:20 Break 16:20 17:15 Session 5: Late Breaking News in AMR Introduction to session Chair: Julian Parkhill 16:20 16:40 How antimicrobials shape Shigella populations Stephen Baker, Cambridge University, UK 16:40 16:50 MinION sequencing for identification of antimicrobial resistance profiles in Vibrio cholerae isolates from three sub- Saharan Africa countries Serges Tchatchouang, Centre Pasteur of Cameroon, Cameroon 16:50 17:00 Whole Genome Sequencing investigation into a Multi-Species Single Site Outbreak of NDM-mediated carbapenem resistance disseminated across predominantly via IncL/M plasmids Nicholas Ellaby, Public Health England, UK 17:00 17:15 Q&A Chair: Julian Parkhill Moderator: Susanna Dunachie 17:15 17:35 Break 17:35 18:35 Lightning talks and poster session (session 2 and 3)

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04-06 November 2020

Friday, 6 November 2020 13:00 15:10 Session 6: Vaccines against AMR Introduction to session Chair: Susanna Dunachie 13:00 13:20 Vaccines for the Prevention and Spread of Antimicrobial Resistance: An Underappreciated Approach Alan Cross, University of Maryland, USA 13:20 13:40 Vaccines to tackle AMR: Opportunities and Knowledge Gaps Elizabeth Klemm, Wellcome, UK 13:40 14:00 Antimicrobial resistance in Salmonella Typhi in India Gagandeep Kang, Christian Medical College, Vellore, India 14:00 14:20 Q&A Chair: Susanna Dunachie Moderator: Iruka Okeke 14:20 15:10 Panel disscussion Chair: Susanna Dunachie Moderator: Iruka Okeke 15:10 15:30 Break 15:30 16:30 Session 7: Population Genomics and AMR Introduction to session Chair: Susanna Dunachie 15:30 15:40 Population genomics and antimicrobial resistance in Corynebacterium diphtheriae Sylvain Brisse, Institut Pasteur, France 15:40 15:50 Genomic epidemiology approaches to understand AMR evolution and selection in Treponema pallidum Mathew Beale, Wellcome Sanger Institute, UK 15:50 16:00 Adaptation to the cervical environment is associated with increased antibiotic susceptibility in Neisseria gonorrhoeae Kevin Ma, Harvard TH Chan School of Public Health, USA 16:00 16:10 Integrated chromosomal and plasmid sequence analyses reveal diverse modes of carbapenemase gene spread among Klebsiella pneumoniae Sophia David, Wellcome Sanger Institute, UK 16:10 16:30 Q&A Chair: Susanna Dunachie Moderator: Iruka Okeke 16:30 16:50 Break 16:50 17:50 Lightning talks and poster session (session 4 and 5) 17:50 18:30 Keynote 2 Introduction to Keynote Chair: Susanna Dunachie 17:50 18:20 Blending clinical and WGS for large studies in LMICs: The challenges and pitfalls Tim Walsh, Cardiff University, UK 18:20 18:30 Q&A Chair: Susanna Dunachie Moderator: Iruka Okeke 18:30 18:40 Closing remarks Scientific Programme Committee: Susanna Dunachie, Nuffield Department of Medicine, UK Iruka Okeke, University of Ibadan, Nigeria Julian Parkhill, University of Cambridge, UK Sharon Peacock, London School of Hygiene and Tropical Medicine, UK

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