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Cytotest Inventory (Filrmaker14)

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Cytotest Inventory (Filrmaker14) The ERBB2/CCP17 FISH Probe Kit is designed to detect the human ERBB2 gene located on chromosome band 17q12, along with the number of chromosome 17 copies per cell. Abnormal expression of the ERBB2 gene – also known as NEU, NGL, HER2, TKR1, CD340, HER-2, MLN 19 or HER-2/neu – has been observed in breast carcinoma and many other solid tumor types. To measure the copy number of the human LSP ERBB2 FISH Probe CytoGreen gene located on chromosome band CCP17 FISH Probe CytoOrange 17q12. LSP ERBB2 FISH Probe covers a chromosomal region which includes the entire gene. CCP17 FISH Probe, derived from chromosome 17-specific alpha satellite DNA, is designed to serve as a control to determine the number of chromosome 17 copies per cell. Normal Patterns Abnormal Patterns CT-PAC001-10-GO 10 Tests (100 μL) 2O2G Other Patterns *Overlapping orange and green signals can appear as yellow. 1) Coussens L, et al. Science. 230(4730):1132-9 (1985). 2) Slamon DJ, et al. Science. 235(4785):177-82 (1987). 3) Heselmeyer-Haddad K, et al. Cancer Res. 62(8):2365-9 (2002). 4) Pauletti G, et al. J Clin Oncol. 18(21):3651-64 (2000). 5) Pathmanathan N & Bilous AM. Pathology. 44(7):587-95 (2012). V2015.03.01 © CytoTest Inc. www.cytotest.com MK-DS-PAC001-EN The ERBB2/CCP17 FISH Probe Kit is designed to detect the human ERBB2 gene located on chromosome band 17q12, along with the number of chromosome 17 copies per cell. Abnormal expression of the ERBB2 gene – also known as NEU, NGL, HER2, TKR1, CD340, HER-2, MLN 19 or HER-2/neu – has been observed in breast carcinoma and many other solid tumor types. To measure the copy number of the human LSP ERBB2 FISH Probe CytoOrange gene located on chromosome band CCP17 FISH Probe CytoGreen 17q12. LSP ERBB2 FISH Probe covers a chromosomal region which includes the entire gene. CCP17 FISH Probe, derived from chromosome 17-specific alpha satellite DNA, is designed to serve as a control to determine the number of chromosome 17 copies per cell. Normal Patterns Abnormal Patterns CT-PAC001-10-OG 10 Tests (100 μL) 2O2G Other Patterns *Overlapping orange and green signals can appear as yellow. 1) Coussens L, et al. Science. 230(4730):1132-9 (1985). 2) Slamon DJ, et al. Science. 235(4785):177-82 (1987). 3) Heselmeyer-Haddad K, et al. Cancer Res. 62(8):2365-9 (2002). 4) Pauletti G, et al. J Clin Oncol. 18(21):3651-64 (2000). 5) Pathmanathan N & Bilous AM. Pathology. 44(7):587-95 (2012). DCN: 027 V2015.03.01 © CytoTest Inc. www.cytotest.com MK-DS-PAC001-EN The TERC/CCP7 FISH Probe Kit is designed to detect the human TERC gene located on chromosome band 3q26.2, along with the number of chromosome 7 copies per cell. Amplification and abnormal expression of the TERC gene – also known as TR, hTR, TRC3, DKCA1, PFBMFT2 or SCARNA19 – is a hallmark of malignant cervical cancer but also is dysregulated in other tumor types. To measure the copy number of the human LSP TERC FISH Probe CytoOrange TERC gene located on chromosome band CCP7 FISH Probe CytoGreen 3q26.2. LSP TERC FISH Probe covers a chromosomal region which includes the entire TERC gene. CCP7 FISH Probe, derived from chromosome 7-specific alpha satellite DNA, is designed to serve as a control to determine the number of chromosome 7 copies per cell. Normal Patterns Abnormal Patterns CT-PAC002-10-OG 10 Tests (100 μL) 2O2G Other Patterns *Overlapping orange and green signals can appear as yellow. 1) Blackburn EH. Nature. 350(6319):569-73 (1991). 2) Shay JW & Bacchetti S. Eur J Cancer. 33(5):787-91 (1997). 3) Heselmeyer K, et al. Proc Natl Acad Sci U S A. 93(1):479-84 (1996). 4) Heselmeyer-Haddad K, et al. Am J Pathol. 166(4): 1229–1238 (2005). 5) Andersson S, et al. Am J Pathol. 175(5): 1831–1847 (2009). DCN: 027 V2015.03.01 © CytoTest Inc. www.cytotest.com MK-DS-PAC002-EN The TERC/TERT/CCP7 FISH Probe Kit is designed to detect the human TERC and TERT genes located on chromosome band 3q26.2 and 5p15.33, respectively, along with the number of chromosome 7 copies per cell. Abnormal expression of both genes (TERC –alsoknownasTR, hTR, TRC3, DKCA1, PFBMFT2 or SCARNA19 – and TERT – also known as TP2, TRT, CMM9, EST2, TCS1, hTRT, DKCA2, DKCB4, hEST2 or PFBMFT1) has been observed in cervical carcinoma and a variety of other tumor types. To measure the copy number of the human LSP TERC FISH Probe CytoOrange TERC and TERT gene located on chromosome LSP TERT FISH Probe CytoGreen band 3q26.2 and 5p15.33, respectively. CCP7 FISH Probe CytoAqua LSP TERC FISH Probe covers a chromosomal region which includes the entire TERC gene. LSP TERT FISH Probe covers a chromosomal region which includes the entire TERT gene. CCP7 FISH Probe, derived from chromosome 7-specific alpha satellite DNA, is designed to serve as a control to determine the number of chromosome 7 copies per cell. Normal Patterns Abnormal Patterns CT-PAC003-10-OGA 10 Tests (100 μL) 2O2G2A Other Patterns *Overlapping orange and green signals can appear as yellow. 1) Blackburn EH. Nature. 350(6319):569-73 (1991). 2) Shay JW & Bacchetti S. Eur J Cancer. 33(5):787-91 (1997). 3) Heselmeyer K, et al. Proc Natl Acad Sci U S A. 93(1):479-84 (1996). 4) Heselmeyer-Haddad K, et al. Am J Pathol. 166(4): 1229–1238 (2005). 5) Visnovsky J, et al. Neuro Endocrinol Lett. 35(6):518-22 (2014). DCN: 027 V2015.03.01 © CytoTest Inc. www.cytotest.com MK-DS-PAC003-EN The TERT/CCP5 FISH Probe Kit is designed to detect the human TERT gene located on chromosome band 5p15.33, along with the number of chromosome 5 copies per cell. Gains and losses of portions of the TERT gene – also known as TP2, TRT, CMM9, EST2, TCS1, hTRT, DKCA2, DKCB4, hEST2 or PFBMFT1 – have been reported in a variety of tumor types. To measure the copy number of the human LSP TERT FISH Probe CytoOrange TERT gene located on chromosome band LSP D5S23,D5S721 FISH Probe CytoGreen 5p15.33. LSP TERT FISH Probe covers a chromosomal region which includes the entire TERT gene. CCP5 FISH Probe, derived from chromosome 5-specific alpha satellite DNA, is designed to serve as a control to determine the number of chromosome 5 copies per cell. Normal Patterns Abnormal Patterns CT-PAC004-10-OG 10 Tests (100 μL) 2O2G Other Patterns *Overlapping orange and green signals can appear as yellow. 1) Blackburn EH. Nature. 350(6319):569-73 (1991). 2) Shay JW & Bacchetti S. Eur J Cancer. 33(5):787-91 (1997). 3) Heselmeyer K, et al. Proc Natl Acad Sci U S A. 93(1):479-84 (1996). 4) Chen SM, et al. Asian Pac J Cancer Prev. 13(5):2063-8 (2012). 5) Visnovsky J, et al. Neuro Endocrinol Lett. 35(6):518-22 (2014). DCN: 027 V2015.03.01 © CytoTest Inc. www.cytotest.com MK-DS-PAC004-EN The TERC/PTGS2/CCP7 FISH Probe Kit is designed to detect the human TERC and PTGS2 genes located on chromosome band 3q26.2 and 1q31.1, respectively, along with the number of chromosome 7 copies per cell. Abnormal expression of both genes (TERC –alsoknownasTR, hTR, TRC3, DKCA1, PFBMFT2 or SCARNA19 – and PTGS2 –alsoknownasCOX2, COX-2, PHS-2, PGG/HS, PGHS-2, hCox-2 or GRIPGHS) has been observed in cervical carcinoma, various other solid tumor types, and other conditions. To measure the copy number of the human LSP TERC FISH Probe CytoOrange TERC and PTGS2 gene located on chromosome LSP PTGS2 FISH Probe CytoGreen band 3q26.2 and 1q31.1, respectively. CCP7 FISH Probe CytoAqua LSP TERC FISH Probe covers a chromosomal region which includes the entire TERC gene. LSP PTGS2 FISH Probe covers a chromosomal region which includes the entire PTGS2 gene. CCP7 FISH Probe, derived from chromosome 7-specific alpha satellite DNA, is designed to serve as a control to determine the number of chromosome 7 copies per cell. Normal Patterns Abnormal Patterns CT-PAC005-10-OGA 10 Tests (100 μL) 2O2G2A Other Patterns *Overlapping orange and green signals can appear as yellow. 1) Shay JW & Bacchetti S. Eur J Cancer. 33(5):787-91 (1997). 2) Heselmeyer K, et al. Proc Natl Acad Sci U S A. 93(1):479-84 (1996). 3) Zha S, et al. Cancer Lett. 215(1):1-20 (2004). 4) Rask K, et al. Mol Cancer. 16;5:62 (2006). 5) Konstantinopoulos PA, et al. Int J Colorectal Dis. 22(1):57-68 (2007). DCN: 027 V2015.03.01 © CytoTest Inc. www.cytotest.com MK-DS-PAC005-EN The PTGS2/CCP1 FISH Probe Kit is designed to detect the human PTGS2 gene located on chromosome band 1q31.1, along with the number of chromosome 1 copies per cell. Abnormal expression of the PTGS2 gene – also known as COX2, COX-2, PHS-2, PGG/HS, PGHS-2, hCox-2 or GRIPGHS – has been observed in colorectal, lung, uterine, ovarian, pancreatic and many other tumor types. To measure the copy number of the human LSP PTGS2 FISH Probe CytoOrange PTGS2 gene located on chromosome band CCP1 FISH Probe CytoGreen 1q31.1. LSP PTGS2 FISH Probe covers a chromosomal region which includes the entire PTGS2 gene. CCP1 FISH Probe, derived from chromosome 1-specific alpha satellite DNA, is designed to serve as a control to determine the number of chromosome 1 copies per cell.
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