world-class cardiovascular care close to home

For more than 50 years, Los Robles Health System has led the way in providing a full range of diagnostic and treatment options for all areas of cardiovascular “I am blessed care, leading to the best outcomes for our patients. Our multi-disciplinary that I have the privilege to team is focused on and vascular health, from diagnosis of heart disease consult and be to management of heart failure and everything in between. Our outcomes for treated by the heart care are consistently in the nation’s top 10 percent and we participate in best doctors multiple cutting edge clinical trials. in the world,” says Morris K., What cardiovascular cases do we serve? 90-year-old Israeli The Cardiovascular Institute of Los Robles Health System has some of the most businessman and philanthropist. talented cardiac experts in the industry, spanning specialties and disciplines. “I could have gone anywhere As such, we provide a complete range of cardiac care, readily handling cases in the world, but I chose Los from the most straightforward to the most complex. Internationally renowned, Robles.” Morris K., after undergoing the patients come from around the world to be treated at Los Robles. minimally invasive Mitraclip G4 procedure at Los Robles Health System Los Robles Cardiovascular Highlights and Firsts • First hospital in the US (in conjunction with sister hospital St. David’s in Texas) to perform the WATCHMAN FLX procedure for AFib • First hospital in the world to use the MitraClipG4TM for minimally invasive treatment of mitral valve regurgitation • First in Greater Los Angeles County — Tricupsid Triluminate Clinical Trial for the treatment of tricuspid regurgitation • First in the Ventura County — V-Wave Clinical Trial for the treatment of congestive heart failure • First hospital in the Conejo and San Fernando Valleys to perform for the treatment of AFib • First hospital in Ventura County to perform the minimally invasive TAVR Los Robles is proud to provide procedure to replace narrowed aortic valves training for thousands of interventional cardiologists Vital Stats: around the world performing live case broadcasts for 2020 382 STEMI Receiving Structural conferences including the Emory Licensed Beds Center Heart Cases Practical Intervention Course for both Los Angeles and such as TAVR for Aortic Valve, MitraClip for Interventional Cardiologists Ventura Counties for the Mitral Valve, TricClip for the Tricuspid and Cardiac Surgeons and the valve, Revivent for the left , and Chinese Structural Heart Week Emergency visits: other minimally invasive surgical and 54,632 Watchman catheter based therapies Conference. for stroke prevention in patients with non-valvular AFib Cardiac Rhythm Therapies Births: Surgeries: Complex Corornary including ablation, device implants, leadless 1,736 17,155 Interventions pacemakers and cardiac defibrillators. Our including patients with Arrythmia Center facilitates timely rhythm (2019) chronic total occlusions management

Los Robles Health System 215 W. Janss Road. | Thousand Oaks, CA 91360 805.852.9100 | LosRoblesHospital.com What cardiovascular research are we doing? “It really is In close collaboration with HCA Research Institute, the Cardiovascular Institute of amazing, I felt Los Robles Health System is engaged with several cutting edge clinical trials, with immediately many more in the pipeline: better just CLASP IID + IIF: Edwards PASCAL Highlife Medical HL-2019-01: An Early three hours TrAnScatheter Valve RePair System Feasibility Study of the HighLife 28mm after the Pivotal Clinical Trial (CLASP IID/IIF): A Trans-Septal Transcatheter Mitral Valve procedure,” prospective, multicenter, randomized, Replacement System. says 78-year- controlled pivotal trial to evaluate the old Kathleen, a safety and effectiveness of transcatheter Abbott SUMMITT: Clinical Trial to vivacious great grandmother with the Edwards Evaluate the Safety and Effectiveness of 9. “I was walking down the PASCAL Transcatheter Valve Repair of Using the Tendyne Mitral Valve hallways of the hospital so fast. System compared to Abbott MitraClipTM Replacement System for the Treatment My nurse Samantha asked if I in patients with mitral regurgitation. of Symptomatic Mitral Regurgitation. walked this fast all the time.” Kathleen M., after being among the Boston Scientific OPTION: Comparison RELIEVE-HF TRIAL - Provide reasonable first in the US to have the Triluminate of Anticoagulation with Left Atrial assurance of safety and effectiveness of Tricuspid device implanted at the Appendage Closure after AF Ablation. the V-Wave Interatrial Shunt System to Cardiovascular Institute of Los Robles Health System reduce lung congestion symptoms and Abbott Repair MR: Percutaneous improve clinical outcomes in a certain TM MitraClip Device or Surgical Mitral high-risk subset of symptomatic patients “I’m breathing Valve REpair in PAtients with PrImaRy suffering from heart failure. easier than MItral Regurgitation who are Candidates I was Abbott Portico NG: for Surgery (REPAIR-MR). Evaluation of the before the Portico™ NG Transcatheter Aortic Valve Watchman Abbott TRILUMINATE Pivotal: in High and Extreme Risk Patients with procedure,” Evaluate the safety and effectiveness of Symptomatic Severe Aortic Stenosis. TM says Paul, who the TriClip device in improving clinical was back to Halfmoon Medical: outcomes in symptomatic patients with Evaluation of the work the day after severe tricuspid regurgitation who have Safety and Performance of the Half receiving the new Watchman been determined by the site’s local heart Moon Transcatheter Mitral Valve Repair FLX implant. “I believe that team to be at intermediate or greater System in High Risk Patients with Severe, 90% is attitude. I’m looking estimated risk for mortality with tricuspid Symptomatic Mitral Regurgitation - The forward to feeling better as valve surgery. Half Moon TMVr Pilot Study the weeks go on.” Paul D., two weeks after being among Bioventrix ALIVE trial: American Less Boston Scientific Champion AF: the first in the US to undergo the Invasive Ventricular Enhancement - The WATCHMAN FLX versus NOAC for Watchmnan FLX procedure Revivent system for the treatment of post EMbolic ProtectION in the Management infarction (AMI) ischemic heart failure of Patients with Non-Valvular Atrial Are you looking for a through catheter based ventricular repair. Fibrillation Cardiovascular Specialist? Boston Scientific Protected TAVR: Abbott AMPLATZER™ PFO Occluder We offer the full-spectrum Stroke PROTECTion with SEntinel During Post Approval Study of heart care at Transcatheter Aortic Los Robles Health System.

Abbott MitraClipTM Expand G4: MitraClipTM G4 System Evaluate Call 877.888.5746, the safety and performance of the to refer your patient MitraClipTM G4 System in a post-market to one of our expert setting. physicians. For more details about our Clinical Trials, please visit LosRoblesHospital.com/service/heart-clinical-trials or contact:

Mane Arabyan - Research Coordinator [email protected] | 805.796-3746

Cherry Papanicalaou - Research Coordinator [email protected] | 805.368.1803 10.20 Los Robles Health System 215 W. Janss Road. | Thousand Oaks, CA 91360 805.852.9100 | LosRoblesHospital.com