NASS 2020 Virtual Experience October 6-9, 2020 Final Program

Welcome and Access Information: 2 Education Information: 3

Attendee Resources: 4 Awards: 5

Corporate Supporters: 8 Meeting-at-a-Glance: 9

Tuesday, October 6: 14 Wednesday, October 7: 16

Thursday, October 8: 25 Friday, October 9: 35

OnDemand: 41 Abstracts: 51

Leadership Recognition: 111 Disclosure Policy Information: 113 Welcome to the NASS 2020 Virtual Experience 2 October 6-9 and Beyond Earn up to 51.25 AMA PRA Category 1 CreditsTM.

The Virtual Lobby Platform is your window Accessing Virtual Content After the to the meeting. View the Live Session Meeting schedule, Session Library, Exhibitor ALL of the Virtual Meeting content will be accessible at Gallery, Abstracts, Discussion boards and spine.org/AM through March 2021 and in your personal NASS Resources from the Virtual Lobby. NASS Video Library indefinitely.

Use the Live Schedule to access the session you want to watch. Access the OnDemand Session Library to view sessions by category at any time as well as to watch We look forward to your participation sessions not featured in the live schedule. in the NASS Annual Meeting Virtual

Exhibitor Gallery houses company products, listing by Experience, October 6-9 and company and a video gallery. thereafter OnDemand.

Read the hundreds of abstracts available via the Virtual Lobby. View the scientific research, watch a video, chat or posts comments for colleagues and authors. William J. Sullivan, MD Discussions allow you to continue the conversation after 2019-2020 NASS President the sessions conclude. Post comments to the sessions by category on the discussion boards. Michael G. Fehlings, Use the NASS Resources portal to access your member benefits, join or renew your membership, view offers and MD, PhD, FRCSC find the latest publications. 2020 Program Co-chair

Accessing the Virtual Meeting David J. Kennedy, MD Go to spine.org/AMVirtualLobby and log in to the 2020 Program Co-chair meeting using your NASS username and password. Don’t remember your login? Your login is your email address. You also can reset your password if necessary. You’ll use the same link each day to access the Live Schedule and Donna M. Lahey, the OnDemand Session Library. RNFA, CNOR 2020 Program Co-chair Watch each session using the Virtual Session Platform. Ask a question during live sessions using the chat feature.Click the Discussions icon to post comments and Alexander R. Vaccaro, observations, as well as direct questions to speakers via MD, PhD a designated email. Click the Session Details link to view 2020 Program Co-chair moderators, description and objectives. The Speaker link will show presenters and their disclosures. There’s also posting etiquette under the Guidelines link.

Disclaimer The material presented at the NASS 2020 Virtual Annual Meeting is made available by the North American Spine Society for educational purposes only. The material is not intended to represent the only, nor necessarily the best, method or procedure appropriate for the medical situations discussed; rather, it is intended to present an approach, view, statement or opinion of the faculty which may be helpful to others who face similar situations.

While NASS will take commercially reasonable measures to ensure this virtual meeting is available without significant interruption, difficulties with hardware, software, equipment or services especially those provided by others may result in some interruptions. In such events, all content will be available OnDemand for users to later view at his/her own convenience. NASS disclaims any and all liability for injury or other damages to any individual attending the meeting and for all claims which may arise, including those arising out of the use of the techniques demonstrated therein by such individuals, whether these claims shall be asserted by physicians or any other person. Education Information 3

Learning Objectives Upon completion of this meeting, participants should gain strategies to: • Promote discussion of new scientific developments and best practices in spine care; • Demonstrate the application of current techniques, procedures and research; • Practice evidence- and value-based medicine relative to spine care.

CME Information Questions? Contact NASS Education at [email protected].

How to Claim your CME Evaluation and Educational Certificates Log into your NASS account via www.spine.org/CME to After the meeting, you may submit your evaluation claim CME.You will not be able to submit answers or print electronically and print your CME certificate directly from a certificate until the meeting concludes on Friday, October our website. Visit www.spine.org/cme to claim education 9 at 5:30 p.m. CT credit and to print CME certificates. Contact [email protected] with questions.

Continuing Medical Education (CME) Continuing Education (CE) Credit for Credit Allied Health Professionals This activity has been planned and implemented in NASS is proud to offer continuing education (CE) units accordance with the Essentials and Standards of the to accommodate nonphysician attendees’ certification Accreditation Council for Continuing Medical Education requirements. The following indicates the status of CE unit (ACCME). The North American Spine Society is accredited accreditation for nonphysician attendees. Requirements by the ACCME to provide continuing medical education for vary for other allied health and advanced practice physicians and takes responsibility for the content, quality providers; please contact your licensing organization for and scientific integrity of this CME activity. their requirements.

The North American Spine Society designates this enduring Physician Assistants: The American Academy of Physician material for a maximum of 49.75 AMA PRA Category Assistants (AAPA) accepts Category 1 credit from 1 CreditsTM. Physicians should claim only the credit AOACCME, prescribed credit from the American Academy commensurate with the extent of their participation in the of Family Physicians (AAFP) and AMA PRA Category 1 activity. (This includes the Live Schedule content.) CreditsTM for the Physician’s Recognition Award from organizations, such as NASS, accredited by the ACCME. The American Medical Association has determined that physicians not licensed in the US who participate in Nurse Practitioners: The American Association of Nurse these CME activities are eligible for AMA PRA Category 1 Practitioners (AANP) accepts AMA PRA Category 1 CreditsTM. CreditsTM from organizations accredited by the ACCME.

Requirements vary for other allied health and advanced practice providers; please contact your licensing organization for their requirements.

To claim CME credit and to print certificates after the meeting, please visit www.spine.org/cme. Request usernames and passwords from the login page. Attendee Resources 4

Virtual Member Concierge NASS Publications We encourage you to visit the Virtual Membership The Spine Journal Concierge in the NASS Resources section of the virtual The Spine Journal is the official scientific journal of NASS experience to check for meeting offers related to and the highest-rated journal in spine science. TSJ is an membership. There you’ll be able to renew your 2021 dues, international, multidisciplinary peer-reviewed journal that join NASS, browse the Digital Recruitment Guide powered publishes original articles on research and treatment of the by the NASS Career Center, and more! spine and spine care.

Members who renew for 2021 will also gain access to The Find The Spine Journal online at: Best of NASS Annual Meetings: Bonus Content. This is www.thespinejournalonline.org a collection of the most popular OnDemand sessions of Submit articles to The Spine Journal 2018 and 2019 with an additional 21 CME credits! at: https://www.editorialmanager.com/ SPINEE/default.aspx Not a member? Join today at www.spine.org/join and receive 50% off your 2021 Membership! To gain access to your exclusive promotion code, Text* ASKNASS to 33222 NEW! NASSJ or send an email to [email protected]. NASSJ, the open access companion to The Spine Journal, is a new international, evidence-based, online journal. Questions? NASSJ publishes peer-reviewed original content on clinical Feel free to contact us at [email protected] or give care, spine research and education. Readers and authors us a call at 866-960-6277 (001-630-230-3600 from outside have a new opportunity to experience traditional and the United States), Monday–Friday, 8:00 a.m.–4:00 p.m. unique article types in this opening accessible and rapidly Central time. You can also Text the word ASKNASS to available new publication. 33222 from any US phone number*. Find NASSJ at: *By texting you agree to receive automated text messages https://www.nassopenaccess.org from NASS (frequency based on level of communication). Message and data rates may apply. Reply STOP to end. Text Find Instructions for Submitting communication is limited to United States phone numbers only. Manuscripts to NASSJ at: https://www. nassopenaccess.org/content/authorinfo

SpineLine SpineLine, a peer-reviewed bimonthly clinical and news publication of NASS, includes multidisciplinary scientific articles, reviews, debates, and other relevant medical, ethical and policy content in spine and health care.

Find SpineLine at: www.spineline-digital.org

KnowYourBack KnowYourBack.org is NASS’ peer-reviewed patient page. With content supplied by the Patient Education and Public Affairs committee, KnowYourBack offers you a credible information source where you can feel confident about sending your patients. Topics range from prevention to diagnoses and treatments. NASS members should check on and update their Patient Profile on their MyAccount page and reach more patients via KnowYourBack’s Find a Specialist feature. Find your profile at: https://connect.spine.org/network/members/profile. Awards 5

2020 NASS Recognition Awards Available OnDemand

Dr. Guyer is a 34-year member of NASS, 2006-2007 NASS President, Co- Founder of Texas Back Institute in 1982, one of the pre-eminent practices in spine globally, Founder and Chairman of the TBI Research Foundation and Director, and TBI Spine Fellowship since 1986 having trained more than 225 domestic and international fellows. TBI’s research in clinical studies including discographies, MRI’s, MIS surgeries and total disc replacements serve as seminal studies to this day. His Foundation is the recipient of grants and numerous accolades including the prestigious Volvo Award for low back pain research. He has a long running list of past committees at NASS and continues 2020 Leon Wiltse Award to be active with NASS on TSJ, the former Motion Preservation Section, hosting Chinese spine surgeons as part of the NASS CAOS Spine Fellows Program, and Richard D. Guyer, MD participating in NASS’ International Education Programs. Along with his partners, he has participated in nearly a dozen FDA IDE trials. Most recently, he has been Recognizing excellence in the Co-Principal Investigator in two of the most recent cervical disc trials, the leadership and/or clinical research M-6 and the Simplify. His research in the clinical sciences remains relevant and in spine care. serves in numerous clinical algorithms outlining spine care.

Nominated by Scott Blumenthal, MD and Jean-Jacques Abitbol, MD

Dr. Boyan is a 6-year member of NASS, presently Alice T. and William H. Goodwin, Jr. Dean of Engineering at the Virginia Commonwealth University, where she is also the Professor of Biomedical Engineering, with affiliate appointments in Biochemistry, Pediatrics and Orthopedic Surgery and Professor Emerita at the Georgia Institute of Technology. Her remarkable contributions to spine-related basic science have been important in educating the NASS membership about the interactions between spine implant materials, surfaces, and bone physiology. Colleagues know Dr. Boyan through her work on the interaction of osteoblasts lineage cells with biomaterials used in spine for interbody fusions, including bone graft substitutes and metal cages. She has been instrumental in helping surgeons 2020 Henry Farfan Award to understand the underlying concepts in bone biology that are involved in this Barbara D. Boyan, PhD interaction and how different materials, particularly their surface properties, impact osteogenesis during the fusion process. Dr. Boyan has published over 500 Recognizing outstanding peer-reviewed papers, most of which have addressed basic questions related contributions in spine-related basic to musculoskeletal research. Her papers span the field from basic cell biology science research. and mechanisms of hormone and growth factor regulation to the development of preclinical models that address actual clinical use. She has been able to convert her knowledge in basic science to inventions that are used clinically worldwide. She served on the FDA’s Orthopaedic Device Panel for six years and was chair when spine cages were first introduced. She has served as a member of the panel for the review of BMP2/Infuse and she has represented AAOS at CMS. Barbara holds 23 issued US patents. She is a member of the National Academy of Engineering, and a Fellow of the National Academy of Inventors, the American Association for the Advancement of Science, the American Institute of Mechanical and Biomedical Engineering, the European Academy of Science and Arts, and the National Academy of Inventors and the International College of Fellows of Biomaterials Science and Engineering. She has founded a number of biomedical technology companies and has served on the Boards of both public and private companies, as well as not-for-profit organizations and government agencies, including the Commonwealth Center for Advanced Manufacturing and the Virginia Innovation Partnership Authority.

Nominated by Paul Slosar, MD and Gunnar Andersson, MD, PhD Awards 6

Dr. Klein is a 11-year member of NASS, a Clinical Professor, Dept. of Orthopedic Surgery, Univ. of California – Davis, and a Moderator and Facilitator of NASS’ online forum, Spine Connect. He currently serves on three NASS committees. He is very committed to fostering the educational mission of NASS, as the on-line facilitator of SpineConnect and as moderating SpinePAC symposiums at the 2016 and 2017 Annual Meetings. As Co-chair of the SpinePAC Advisory Committee, he feels we are fulfilling our obligation to the membership, that via Advocacy, NASS has a voice in Washington. He has co-hosted five SpinePAC fund raising dinners and plan to continue. Through his combined efforts, SpinePAC had its most successful fund raising in 2018, surpassing all previous 2020 David Selby Award years. His educational contributions to SpineConnect as facilitator, focuses on Michael R. Klein Jr., stimulating and encouraging our world-wide colleagues to post clinical cases MD, FACS with teaching issues, as well as encouraging spine care providers to ask for assistance in difficult deformity cases and occasionally trauma cases. Since Recognizing contributions to the taking on this position in 2015, the membership of SpineConnect has doubled. art and science of spinal disorder He has not published any manuscripts from this format; however, he chose management through service to four cases from posters who represented four different continents, stressing NASS but has not been elected the importance of NASS’s commitment to worldwide education. These four NASS President. posters came to the 2016 and 2017 Annual Meetings and were well received by the assembled conferees. Dr. Klein’s contribution as Co-Chair of the SpinePAC Advisory Committee stresses that NASS requires funding to continue and maintain a voice in Washington for our membership.

Nominated by Eric J. Muehlbauer, MJ, CAE

Dr. Wang earned a Bachelor of Science degree in Biological Sciences at Stanford University and his M.D. degree at the University of Pittsburgh School Of Medicine. He did his residency in Orthopaedic Surgery at UCLA and completed a fellowship in Spine Surgery at Case Western Reserve University. In 1997, he joined the David Geffen School of Medicine at UCLA as Assistant Professor of Orthopaedic Surgery, in 2002 also was appointed Assistant Professor of Neurosurgery, and became Associate Professor in both disciplines in 2003. He became Vice Chair of the Department of Orthopaedic Surgery and spine fellowship director since 1997. In 2013, he was recruited to the University of Southern California Spine Center. He is currently a Professor of Orthopaedic 2020 Spine Advocacy Award: Surgery and Neurosurgery at the Keck Medical Center at USC, Co-Director of the Jeffrey C. Wang, MD USC Spine Center and Fellowship Director of the USC Spine Fellowship. During Dr. Wang’s tenure as NASS President (2019), NASS Advocacy efforts reached Recognizing members of the new heights setting fundraising and outreach efforts, thanks in large part to North American Spine Society Dr. Wang’s efforts and leadership. During the current election cycle, Dr. Wang who have made exceptional has hosted a SpinePAC fundraising dinner with key health care policy maker contributions to the federal U.S. Rep. Jimmy Gomez (CA-34) and also moderated the NASS COVID-19 joint advocacy efforts on behalf webinar featuring U.S. Rep. Raul Ruiz (CA-36) with AANS/CNS and AAOS. Dr. of patients and members Wang also helped to secure the venue for the 2018 Advocacy Dinner during of the society. the NASS Annual Meeting at the Jonathan Club in . In addition, Dr. Wang continues to lead by example, regularly ranking among the most generous annual donors to SpinePAC.

Nominated by NASS Advocacy Volunteer Leadership Awards 7

Available OnDemand : View award presentations in the Learning Toolbox Abstract Showcase.

The Spine Journal Outstanding Paper Awards 2020 Outstanding Paper in Basic Science: Uncovering molecular targets for regenerative therapy in degenerative disc disease: do small leucine-rich proteoglycans hold the key? Professor S. Rajasekaran, MD, PhD, FACS; Dilip Chand Raja, MS; Chitraa Tangavel, PhD; Sharon Miracle Nayagam, MSc; Vijay Anand, MS; R. Sunmathi, MTech; Monica Steffi Matchado, MTech; M. Raveendran, PhD; Ajoy Prasad Shetty, MS; Rishi Mugesh Kanna, MS; K. Dharmalingam, PhD

2020 Outstanding Paper in Clinical Care: Vertebral bone quality score predicts fragility fractures independently of bone mineral density Jeff Ehresman, BS; Andrew Schilling, AB; Xinghai Yang, MD; Zach Pennington, BS; A. Karim Ahmed, BS; Ethan Cottrill, BS, MS; Daniel Lubelski, MD; Majid Khan, MD; Kendall F. Moseley, MD; Daniel M. Sciubba, MD

2020 Outstanding Paper in Clinical Care: MEMBERS: WHEN YOU RENEW Prospective validation of a clinical prediction score for YOUR 2021 MEMBERSHIP, survival in patients with spinal metastases: The New England Spinal Metastasis Score YOU’LL GAIN ACCESS TO Andrew J. Schoenfeld, MD; Marco L. Ferrone, MD; Joseph THE BEST OF NASS ANNUAL H. Schwab, MD, MS; Justin A. Blucher, MS; Lauren B. Barton, BS; Daniel G. Tobert, MD; John H. Chi, MD, MPH; John H. MEETINGS: BONUS CONTENT. Shin, MD; James D. Kang, MD; Mitchel B. Harris, MD This will feature the most popular OnDemand sessions from 2018 and 2019 with 21 CME credits. With 51.25 credits available for this Research Grant and Fellowship Awards year’s meeting, this will give you access to Research Grant and Fellowship Awards recognize those a total of 72.25 credits! Be sure your 2021 proposing advancements in spine care and research. membership dues are paid by December 31, Jeremiah T. Easley, DVM 2020 and this exclusive content will be made Nima Alan, MD available to you at a later date. Moh H. Malek, PhD Visit spine.org/renew to renew online or call Mohamed Rasheed Ahamed Nihaj, MBBS, MD 866-960-6277, Monday-Friday, 8am-4pm Piyush Kalakoti, MD Central time to renew by phone. Luca Ambrosio, MD

Value Awards Value Abstract Awards foster and recognize efforts to define value in spine care. Azeem T. Malik, MBBS Kibum Kim, PhD Peter Passias, MD

Resident and Fellow Research Awards Resident and Fellow Research Awards recognize young researchers and clinicians who work in spine care. Taylor Jackson, MD Thomas Buell, MD With Sincere Appreciation

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PLATINUM SPONSORS

SILVER SPONSORS

BRONZE SPONSORS Meeting-at-a-Glance 9

CENTRAL TIME ZONE

Tuesday, October 6

1:00–1:45 p.m. Introduction Address with NASS First VP Eeric Truumees, MD Presidential Address with NASS President William J. Sullivan, MD

1:45-2:00 p.m. Break Industry Presentation: Medacta (1:45-1:55)

2:00–3:00 p.m. Concurrent Sessions: Session 1—Sections on Spinal Deformity and Intraoperative Neurophysiological Monitoring: Intraoperative Neuromonitoring and Deformity Surgery

Session 2—Health Care Disruption and Finance: To Brace or Embrace?

3:00–3:15 p.m. Break Industry Presentation: Integra (3:00-3:10)

3:15–4:45 p.m. Surgical Technique Cadaver Demonstration: Endoscopic Spine Fusion Surgery

5:35–5:45 p.m. Industry Presentation: LifeNet Health

Wednesday, October 7 NASS International Forum 8:00–9:00 a.m. NASS International Symposium: Adult Spinal Deformity 9:00–10:00 a.m. NASS International Symposium: Cervical Spine Surgery

10:00–10:25 a.m. Break Industry Presentations: Stryker (10:00-10:10); LifeNet Health (10:10-10:20)

10:25–10:55 a.m. International Address: NASS, EUROSPINE and SPINE20

10:55–11:00 a.m. Break

11:00 a.m.-12:00 p.m. NASS International Symposium: Spine Trauma

12:00–12:45 p.m. Plenary Session: COVID-19: A Cataclysmic Event of Global Significance 12:45–1:00 p.m. Break Industry Presentation: Bioventus (12:45-12:55)

1:00–2:00 p.m. Concurrent Sessions: Session 1—Complex Cervical Deformity: Optimizing Management

Session 2—Section on Biologics & Basic Research: Choosing the Perfect Bone Graft: What are the Biologic Requirements for Fusion by Procedure?

Session 3—Healthcare and the 2020 Elections

2:00–2:30 p.m. Break Industry Presentations: Medtronic (2:00-2:10); Kuros Bioscience (2:10–2:20); Stryker (2:20–2:30)

Continued on next page Surgical Medical All Specialties (Multidisciplinary) Industry Meeting-at-a-Glance 10

CENTRAL TIME ZONE

Wednesday, October 7 (Continued)

2:30–3:30 p.m. Concurrent Sessions: Session 1—Section on Spine Oncology: A Multidisciplinary Approach to Difficult Spine Tumor Case

Session 2—Exercise Committee Presents: The Role of Exercise as Medicine in Spine Care: Matching Exercise Programs to the Patient

3:30–3:45 p.m. Break Industry Presentation: Zimmer Biomet (3:30-3:40)

3:45-4:45 p.m. Featured Abstract Presentation: Best Papers

4:45–5:00 p.m. Break Industry Presentation: Joimax (4:45-4:55) 5:00–7:00 p.m. Surgical Technique Cadaver Demonstration: Spine Deformity Surgery

6:45–7:45 p.m. Industry Workshop: elliquence

7:45-8:45 p.m. Industry Workshop: Ethicon

Thursday, October 8

12:00–1:00 p.m. Plenary Session: Advances and Challenges in Degenerative Cervical Myelopathy

1:00–1:15 p.m. Break Industry Presentation: Medtronic/Mazor (1:00-1:10)

1:15–2:15 p.m. Concurrent Sessions: Session 1—Section on Robotics & Navigation: Pushing the Frontiers of Spine Surgery through Advanced Technologies and Robotics Session 2—Muscle Health as a Biomarker for Functional Recovery Following Spine Pain and Injury

Session 3—Leadership Perspective: Practical Solutions to Impact Physicians’ Professional Fulfillment

2:15–2:45 p.m. Break Industry Presentations: EOS (2:15-2:25); GE (2:25-2:35)

2:45–3:45 p.m. Concurrent Sessions: Session 1—Section on Spinal Cord Injury: Translational Spinal Cord Injury: Advances and Challenges

Session 2—Physiological Modifications for Cost Effectiveness and Enhanced Recovery: Enhanced Recovery After Spine Surgery (ERASS) - Early Results and Implementation

Session 3—Section on Biologics & Basic Research: The Present and Future of Post BMP Biologics

3:45–4:00 p.m. Break Industry Presentation: Vivex (3:45-3:55) Continued on next page Surgical Medical All Specialties (Multidisciplinary) Industry Meeting-at-a-Glance 11

CENTRAL TIME ZONE

Thursday, October 8 (Continued)

4:00-5:00 p.m. Featured Abstract Presentation: Best Papers

5:00–5:15 p.m. Break Industry Presentation: DePuy Synthes (5:00-5:10)

5:15–6:45 p.m. Surgical Technique Cadaver Demonstration: MIS Tubular Decompression 7:00–7:30 p.m. Industry Workshop: Globus Medical 7:30–8:00 p.m. Industry Workshop: Globus Medical 8:00–9:00 p.m. Industry Workshop: DePuy Synthes

Friday, October 9

12:00–1:00 p.m. Plenary Session: Physicians in the Crosshairs: Government Enforcement Trends and Priorities Affecting Physicians and Physician Practices

1:00–1:15 p.m. Break Industry Presentation: Esaote (1:00-1:10)

1:15–2:15 p.m. Concurrent Sessions: Session 1—Endoscopic Spine Surgery: Cost, Data and Advances

Session 2—Sections on Comprehensive Episodes of Spine and Interventional Spine & Musculoskeletal Medicine (ISMM): Disc and Vertebrogenic Pain

Session 3—Artificial Intelligence and Machine Learning in Spine Surgery

2:15–2:30 p.m. Members Business Meeting

2:30–3:40 p.m. Featured Abstract Presentation: Best Papers

3:40–3:45 p.m. Break

3:45–4:45 p.m. Surgical Technique Cadaver Demonstration: Cervical Spine Surgery

4:45–5:00 p.m. Wrap Up/Thank You

Surgical Medical All Specialties (Multidisciplinary) Industry Meeting-at-a-Glance 12

Available in the OnDemand Session Library

Surgical Sessions

Oblique Lumbar Interbody Fusion—Why is it Better?

AOSpine NA: Failed Back Surgery Syndrome Section on Spinal Deformity: Diagnostic and Technology Innovations to Improve Safety, Outcomes and Efficiencies in Spine Deformity Surgery

Section on Intraoperative Neurophysiological Monitoring: To Use, or Not to Use: That is the Question.

Surgical Technique Cadaver Demonstrations: Minimally Invasive Prone Lateral Interbody Fusion Section on Spine Oncology: How Will an Individual Patient Do with Spine Surgery? Using Predictive Models and Calculators

The Sacroiliac Joint: Where Does It Fit Within Your Practice?

Perioperative Optimization in Adult Spinal Deformity

Resident and Fellow Education Pathway

Coding for Residents & Fellows

Career Building

Transition to Practice: Landing A Job

Medical Session

Perioperative Spinal Cord Injury

Ambulatory Care Surgery Practice and Applications: Spine Surgery in the Ambulatory Care Setting: Getting Patients Home Happy

Transforming Your Practice with Minimally Invasive Spine Care Using Evidence-Based Validation

Multidisciplinary Sessions

Interdisciplinary Spine Forum: The Worksite Health Center—An Emerging Model and Opportunity in Value-Oriented Spine Care

Interdisciplinary Spine Forum: Treating Olympic, Paralympic and Elite Athletes

The Future of Value-Based Healthcare in Spine Care: A Multi-Stakeholder Perspective

Interdisciplinary Spine Forum: Thoracic Spine Pathology: Assessment and Differential Diagnosis Interdisciplinary Spine Forum: The Role of First Contact and Patient Interaction in an Attempt to Improve Prognosis and Reduce Chronicity in Patients with Spine Pain Meeting-at-a-Glance 13

Industry Presentations

Abbott—The TRIUMPH of BurstDRTM SCS Therapy: Sustained Improvements in Mental, Physical and Emotional Functioning

Centinel Spine—Tiger Woods: Reborn

Mizuho OSI— Benefits of Intraoperative Adjustments Using the ProAxis® Spinal Surgery Table

Orthofix— Improvements of Quality of Motion and Associated Patient Outcomes

SI-BONE—Complications and Treatment Options for the SI Joint

Spinal Elements Spinal Elements Introduces MIS Ultra

Thompson Surgical, Inc.—Establishing a Successful Anterior Lumbar Practice

Zeiss—An Advanced Visualization System—ZEISS TIVATO® 700 for Spine Surgery—Learn from the Experts Tuesday, October 6 14

1:00–1:45 p.m. Introduction Address: Eeric Truumees, MD Presidential Address: William J. Sullivan, MD

1:45–2:00 p.m. Break Industry Presentation: Medacta (1:45-1:55) The MySpine Experience: Clinical Benefits

CONCURRENT SESSION 2:00–3:00 p.m. SURGICAL SYMPOSIUM: Sections on Spinal Deformity and Intraoperative Neurophysiological Monitoring: Intraoperative Neuromonitoring and Deformity Surgery Moderators: Richard Vogel, PhD, DABNM and Raymond J. Hah, MD

DESCRIPTION AGENDA Intraoperative neuromonitoring is a vital component of Introduction and Basics of Intraoperative improving safety in spinal deformity surgery. Faculty Neuromonitoring will review the basics of intraoperative neuromonitoring, Richard Vogel, PhD, DABNM discuss algorithms for intraoperative changes, and Case Presentation: Signal Loss during Deformity review pathology/technique specific applications of Jason W. Savage, MD intraoperative neuromonitoring. Management of Intraoperative Neuromonitoring Upon completion of the symposium, participants should Signal Loss gain strategies to: Raymond J. Hah, MD • Review the basic principles of intraoperative False Data in Intraoperative Neuromonitoring neuromonitoring; Adam Doan, DC, DABNM • Analyze algorithms for intraoperative changes Intraoperative Neuromonitoring for Spinal Osteotomies in neuromonitoring from the perspective of Jason W. Savage, MD neurophysiologist, anesthesiologist, and surgeon; Intraoperative Neuromonitoring for High Grade • Evaluate common factors that increase the likelihood of Spondylolisthesis acquiring false data in intraoperative neuromonitoring; Hani H. Mhaidli, MD, PhD • Assess the use of neuromonitoring for spinal osteotomies and high-grade spondylolisthesis Case Resolution/Questions and Answers All Faculty Tuesday, October 6 15

CONCURRENT SESSION 2:00–3:00 p.m. MULTIDISCIPLINARY SYMPOSIUM: Healthcare Disruption and Finance: To Brace or Embrace? Moderators: Steven Vanni, DO, DC and Michael P. Steinmetz, MD

DESCRIPTION AGENDA Companies like Amazon, Berkshire Hathaway, Walmart, Is Health Care Ready for Disruption? Apple and JP Morgan want to influence the healthcare Karthik Madhavan, MD system with newer technologies for better patient care Latest Advancements in Technology to Affect Spine and transparency. In this symposium, faculty will discuss Care the recent advances in healthcare that may influence Andrew A. Sama, MD spine surgery and ambulatory surgery centers (ASCs), as well as what to expect in the future. Participants will gain How Does Company Owned Insurance Affect Other insight from Washington insiders and insurance company Insurance Companies? executives. Joseph S. Cheng, MD, MS What is a GPO (Group Purchasing Organization) and Upon completion of the symposium, participants should are Amazon and Walmart the Next Ones? gain strategies to: Chester J. Donnally III, MD • Be aware of latest developments in health care; How Does Bundled Payment Work in this Scenario? • Identify how the new developments affect spine care in Nathaniel P. Brooks, MD the hospital and ASC; Apple, Google, or Amazon Will Be the Next Big Health • Recognize spine bundled payments; Care Organization • Acknowledge the transformation of healthcare with big Anand Veeravagu, MD data and Blue button 2.0; Questions and Answers • Identify aspects of spine surgery facing disruption early. All Faculty

3:00–3:15 p.m. Break Industry Presentation: Integra (3:00-3:10) CSF Leak Prevention with a Dural Sealant Designed Specifically for Spine

3:15–4:45 p.m. SURGICAL TECHNIQUE CADAVER DEMONSTRATION: Endoscopic Spine Fusion Surgery Faculty Presenter: Michael Y. Wang, MD

This surgical technique cadaver demonstration will provide Upon completion of this session, participants should an overview and demonstration of endoscopic spine gain strategies to: fusion surgery. • Incorporate the latest techniques in complex spine surgery into their practice; • Identify the nuances, advantages, and limitation of endoscopic spine surgery.

5:35–5:45 p.m. Industry Presentation: LifeNet Health Expert Panel: Hospitalization Cost And Resource Utilization In U.S. Lumbar Fusion Surgeries Wednesday, October 7 16

8:00–9:00 a.m. NASS INTERNATIONAL SYMPOSIUM: Adult Spinal Deformity Moderators: Patrick C. Hsieh, MD, MS and Hani H. Mhaidli, MD, PhD

DESCRIPTION AGENDA In this session, faculty will address the burden of adult Introduction spinal deformity in healthcare, radiographic analysis and Patrick C. Hsieh, MD, MS pre-operative planning, implants, the optimal osteotomy Burden of Adult Spinal Deformity in Healthcare: selection for correction, and complication avoidance. An International Perspective Jau-Ching Wu, MD, PhD Upon completion of the symposium, participants should gain strategies to: Radiographic Analysis and Pre-operative Planning for • Identify the healthcare burden of adult spinal deformity; Adult Spinal Deformity Jaime Moyano, MD • Describe implant consideration and optimization Pre-operative Optimization for Adult Spinal Deformity • Implement radiographic analysis and pre-operative Surgery planning; Teresa Bas, MD, PhD • Select the optimal osteotomy type for spinal deformity correction; Selecting the Optimal Osteotomy Type for Spinal Deformity Correction • Avoid and manage complications. Bangping Qian, MD Complication Avoidance and Management for Adult Spinal Deformity Surgery Yong Hai, MD, PhD Questions and Answers All Faculty

9:00–10:00 a.m. NASS INTERNATIONAL SYMPOSIUM: Cervical Spine Surgery Moderators: Jeffrey C. Wang, MD and Jean-Jacques Abitbol, MD

DESCRIPTION AGENDA In this global session, faculty will address cervical Introduction myelopathy. Specifically, indications for surgery Jeffrey C. Wang, MD versus conservative treatments, cervical arthroplasty Indications for Posterior Approaches for Cervical for myelopathy, sagittal alignment considerations Myelopathy for myelopathy surgery, and the latest surgical Manabu Ito, MD, PhD recommendations. Clinical and Radiographic Outcomes of Cervical Disc Upon completion of the symposium, participants should Replacement in Treatment of CSD gain strategies to: Zhuojing Luo, MD, PhD • Identify the natural history of cervical myelopathy, Sagittal Alignment Considerations for Myelopathy diagnosis, and indications for surgery versus Surgery conservative treatments; Gabriel K. Liu, MD • Plan the appropriate surgical approaches to the spine Guidelines for the Management of Cervical Myelopathy for the decompression of the spinal cord with optimal Jean-Jacques Abitbol, MD outcomes; Questions and Answers • Learn the role of cervical disc arthroplasty and how it All Faculty can be used for the treatment of cervical myelopathy. Wednesday, October 7 17

10:00–10:25 a.m. Break Industry Presentation: Stryker (10:00-10:10) Mesa: Innovation Continues Industry Presentation: LifeNet Health (10:10-10:20) A Case Against PEEK for ACDF

10:25–10:55 a.m. International Address: NASS, EUROSPINE and SPINE20 Moderator: Jorg Franke, MD

Overview of EUROSPINE Everard Munting, MD, PhD, President Overview of NASS William J. Sullivan, MD, President Overview of SPINE20 Dr. Margareta C. Nordin

10:55–11:00 a.m. Break

11:00 a.m.–12:00 p.m. NASS INTERNATIONAL SYMPOSIUM: Spine Trauma Moderator: Charles A. Reitman, MD

DESCRIPTION AGENDA Faculty will discuss the classification of surgical Introduction indications, how to evaluate and manage the ankylosed Charles A. Reitman, MD spine, MIS in T-L fractures as well as present a case Classification/ Surgical Indications—What is “Unstable?” debate about unstable T12 burst fracture with incomplete Matti Scholz, MD neurologic deficit. Evaluation and Management of TL Fractures in Upon completion of the symposium, participants should Ankylosed Spine gain strategies to: Faisal Konbaz, MBBS • Classify surgical indications; Role and Objectives of MIS in T-L Fractures Jung-Woo Hur, MD • Define what is unstable; Debate—Case is Unstable T12 Burst Fracture with • Evaluate and manage the ankylosed spine; Incomplete Neurologic Deficit • Describe the role and objectives of MIS in T-L fractures. 1. Favor Anterior Surgery Ibrahim Omeis, MD, FAANS 2. Favor Posterior Surgery Baron Zarate, MD Questions and Answers All Faculty Wednesday, October 7 18

12:00–12:45 p.m. PLENARY SESSION: COVID-19: A Cataclysmic Event of Global Significance Moderator: Michael G. Fehlings, MD, PhD, FRCSC

DESCRIPTION AGENDA Join our faculty panel to gain an understanding of the U.S. Perspective on Return to Work, Management of incidence and prevelance of COVID-19 and the impact the Secondary Surge and other Issues Related to the on our world community. Discussions include the Pandemic from a Surgeon Perspective U.S. perspective on returning to work, management Vadim Goz, MD of the secondary surge and issues from many different perspectives including surgical, medical and International Perspective from the Frontlines of Wuhan, multidisciplinary approaches. China Yongchao Wu, MD Upon completion of the symposium, participants should Questions and Answers gain strategies to: All Faculty • Gain an understanding of the incidence and prevalence of COVID 19 in the world community; • Determine effective containment measures now and in the future for such a pandemic; • Determine the effect of this pandemic on future operative and nonoperative care paradigms related to spinal medicine; • Appreciate the timelessness of effective treatment strategies for COVID 19-antiviral/vaccine/passive immunity.

12:45–1:00 p.m. Break Industry Presentation: Bioventus (12:45-12:55) Spinal Fusion Series: Use of OSTEOAMP, a Novel Allograft, in a Variety of Complex Procedures Wednesday, October 7 19

CONCURRENT SESSION 1:00–2:00 p.m. SURGICAL SYMPOSIUM: Complex Cervical Deformity: Optimizing Management Moderator: Shay Bess, MD

DESCRIPTION AGENDA Adult cervical deformity is associated with severe Introduction patient disability, however complications associated with Shay Bess, MD cervical deformity surgery are greater and potentially Fundamental Cervical Spine Alignment Concepts All more catastrophic than complications associated with Surgeons Should Know When Treating Cervical Deformity thoracolumbar deformities. Consequently, many surgeons Virginie Lafage, PhD are unfamiliar or uncomfortable with surgically treating cervical spine deformities. In this session, faculty address Does Cervical Deformity Classification Guide Treatment the assessment and treatment options for adult cervical Justin S. Smith, MD spine deformity. Spinal Osteotomies for Cervical Deformity: Outcomes and Complications Upon completion of the symposium, participants should Christopher P. Ames, MD gain strategies to: Rigid vs. Flexible Cervical Deformity: Diagnosis and • Identify the radiographic parameters most predictive of Treatment Guidelines disability for cervical spine deformities; Robert K. Eastlack, MD • Review how the cervical spine classificationcan Distal Junctional Kyphosis: Diagnosis, Risk Factors and differentiate between deformity types and guide surgical Prevention in Cervical Deformity Surgery treatment; Themistocles Protopsaltis, MD • Differentiate between flexible and rigid cervical Patient-Specific Cervical Deformity Corrections with deformities to help guide treatment options; Consideration of Associated Risk: Establishment of Risk • Recognize catastrophic complications associated Benefit Thresholds for Invasiveness Based on Deformity with cervical deformity surgery and how to avoid these and Frailty Severity complications. Peter G. Passias, MD Questions and Conclusions Shay Bess, MD

CONCURRENT SESSION 1:00–2:00 p.m. MEDICAL SYMPOSIUM: Section on Biologics & Basic Research: Choosing the Perfect Bone Graft: What are the Biologic Requirements for Fusion by Procedure? Moderators: Raymond Hah, MD and R. Todd Allen, MD

DESCRIPTION AGENDA The data regarding efficacy of the various osteobiologics Personal Introspection: What Do You Use for for fusion is limited. There is wide practice variation on the Fusion in These Settings and Why? type and quantity of graft selection. Faculty will explore the Raymond J. Hah, MD existing evidence on osteobiologic choice by procedure Multilevel Anterior Cervical Discectomy and Fusion and more closely examine the rationale for selection. Jeffrey C. Wang, MD Anterior Lumbar Interbody Fusion (Lateral/Oblique) Upon completion of the symposium, participants should R. Todd Allen, MD gain strategies to: Adult Spinal Deformity • Encourage the attendee to think about what Raymond J. Hah, MD osteobiologic choices they make and why; Spinal Oncology • Review the literature on efficacy andcomplications of Daniel M. Sciubba, MD bone graft options in various fusion settings; Questions and Answers • Explore expert opinion on graft selection for obtaining All Faculty successful fusion. Wednesday, October 7 20

CONCURRENT SESSION 1:00–2:00 p.m. MULTIDISCIPLINARY SYMPOSIUM: Healthcare and the 2020 Elections Moderator: Philip L. Schneider, MD, NASS Advocacy Council Director

DESCRIPTION AGENDA Recent polling indicates that health care remains the number Update on NASS Legislative Agenda and State of one issue voters will consider before casting a ballot in this Play in 116th Congress year’s Presidential elections. In this symposium, faculty will Philip L. Schneider, MD take an in-depth look at what the 2020 election may mean for the future of the health care, especially as it pertains to spine What a New Democratic Admin. May Mean For care providers ability to deliver high quality care to patients. Health Care Policy and Spine Care with U.S. Senator Additionally, participants will gain a better understanding of Tina Smith (D-MN) how potential outcomes align with NASS priority objectives Philip L. Schneider, MD and how NASS Advocacy efforts are working to shape this What A Second Trump Admin. May Mean For Health conversation. Care Policy and Spine Care U.S. U.S. Senator Mike Braun (R-IN) Upon completion of the symposium, participants should gain Philip L. Schneider, MD strategies to: • Evaluate how the current political environment is shaping the policies that will affect spine care providers and their patients; • Recognize the legislative proposals that are being considered by Congress as they identify ways to address the major challenges to the U.S. health care system; • Gain an in-depth understanding of NASS’ current federal legislative priorities and emerging trends in healthcare policy in Washington, DC.

2:00–2:30 p.m. Break Industry Presentation: Medtronic (2:00-2:10) Nano Technology meets Navigation: Introducing Adaptix™ Interbody System with Titan nanoLOCK™ Surface Technology Industry Presentation: Kuros Bioscience (2:10-2:20) Immunomodulation by MagnetOs bone graft and a Novel Injectable Parathyroid Hormone for Interbody Fusion Industry Presentation: Stryker (2:20-2:30) Drive to Make Healthcare Better Featuring: Airo TruCT, Bone Vac, Mesa2, Niagara and SpineJack Wednesday, October 7 21

CONCURRENT SESSION 2:30–3:30 p.m. SURGICAL SYMPOSIUM: Section on Spine Oncology: A Multidisciplinary Approach to Difficult Spine Tumor Cases Moderators: Matthew L. Goodwin, MD, PhD; FACSM; Daniel M. Sciubba, MD; and Joseph H. Schwab, MD

DESCRIPTION AGENDA This interactive session will start with a pre-test with Introduction audience participation. The same questions will be asked Daniel M. Sciubba, MD and Joseph H. Schwab, MD at the end of the session (pre/post-test). Faculty will Case 1: Primary Tumors of the Spine and Sacrum present cases that will serve as topics for interactive Matthew L. Goodwin, MD, PhD, FACSM discussion. One of the faculty will be presenting the case while other faculty will for volunteers to answer the Case 2: Metastatic Lesions of the Spine: When is questions as they arise during the case. Each case will Radiation Most Effective? cover a particular challenge in treating spinal tumors. Kristin Redmond, MD, MPH For example, the first case will be a previously operated on sacral that chordoma with a contaminated path from Case 3: Difficult Cases In and About the Spine incision to tumor. Another case will discuss when to re- John H. Shin, MD biopsy if a biopsy is nondiagnostic or unclear. Another Questions and Closing case will address what cases are most appropriate for All Faculty radiation and the challenges in timing of this treatment. Finally, the session will conclude with a variety of challenging cases with a post-test given to participants.

Upon completion of the symposium, participants should gain strategies to: • Perform appropriate workup/treatment of spinal tumors of unknown origin; • Consider appropriate factors in determining treatment of a patient with a contaminated prior open approach to a primary lesion; • Identify criteria for diagnosis and treatment options for metastatic lesions; • Diagnose and treat high grade spinal cord compression from metastatic tumors and understand when radiation is appropriate; • Manage cases when the first biopsy is unclear or nondiagnostic; • Perform appropriate workup/treatment of tumors about the neural elements. Wednesday, October 7 22

CONCURRENT SESSION 2:30–3:30 p.m. MULTIDISCIPLINARY SYMPOSIUM: Exercise Committee Presents: The Role of Exercise as Medicine in Spine Care: Matching Exercise Programs to the Patient Moderator: John M. Mayer, DC, PhD, FACSM

DESCRIPTION AGENDA Therapeutic exercise is well-documented as an effective Introduction intervention across the continuum of care for spinal pain John M. Mayer, DC, PhD, FACSM disorders and is recommended in most major clinicial Matching Exercise to the Patient: General Physical Activity practice guidelines. In this session, faculty will provide Ram Haddas, PhD essential knowledge to help the spine provider make informed decisions to appropriately match exercise Matching Exercise to the Patient: Exercise Dose programs to the unique characteristics of each patient. Mark D. Croucher, DC Matching Exercise to the Patient: Specific Back and Core Upon completion of the symposium, participants Exercises should gain strategies to: Yoheli Perez, PT • Describe the benefits of exercise for general health and various conditions relevant to spine care (e.g. Matching Exercise to the Patient: Directional Preference osteoporosis, osteoarthritis, rheumatoid arthritis, Ryan A. Tauzell, PT, MA, Cert. MDT sarcopenia, obesity); Matching Exercise to the Patient: Behavioral Health • Distinguish between specific and generalexercises for Considerations spine care applications; Donald R. Murphy, DC, FRCC • Choose the appropriate dose of exercise to support Matching Exercise to the Patient: Nutritional and Weight spine care; Management Considerations • Identify the behavioral and nutritional considerations Brittany V.B. Johnson, MS, RDN, CSSD associated with exercise; Summary • Apply the knowledge learned to prescribe exercise John M. Mayer, DC, PhD, FACSM programs for spine care.

3:30–3:45 p.m. Break Industry Presentation: Zimmer Biomet (3:30-3:40) mymobility® with Apple Watch® a New Standard in Digital Health Wednesday, October 7 23

3:45–4:45 p.m. FEATURED ABSTRACT PRESENTATION: Best Papers Moderators: Jefferson Wilson, MD, PhD, FRCSC and Michael G. Fehlings, MD, PhD, FRCSC

3:45–3:52 p.m.

1. Use of ALIF at the lumbosacral junction 1Scripps Clinic, San Diego, CA, US; 2University of Calgary, Calgary, Canada; results in less lumbopelvic fixation failure than 3Scripps Clinic Medical Group, Department of Orthopedics, La Jolla, CA, 4 5 TLIF or no interbody fusion following correction US; UVA Health System, Charlottesville, VA, US; Denver International 6 of adult spinal deformity Spine Center, Denver, CO, US; NY Spine Institute, NYU Langone Health, New York, NY, US; 7Spine Institute of Louisiana, Shreveport, LA, 1 Robert K. Eastlack, MD ; Alexandra Soroceanu, MD, US; 8Pittsburgh, PA, US; 9Duke University, Durham, NC, US; 10Barrow 2 3 MPH ; Gregory M. Mundis Jr., MD ; Justin S. Smith, MD, Neurological Institute, Phoenix, AZ, US; 11University of California San 4 5 6 PhD ; Breton Line, BS ; Peter G. Passias, MD ; Pierce Francisco, San Francisco, CA, US; 12Johns Hopkins University, Baltimore, 7 8 D. Nunley, MD ; David O. Okonkwo, MD ; Khoi D. Than, MD, US; 13Denver, CO, US; 14Brighton, CO, US MD9; Juan S. Uribe, MD10; Dean Chou, MD11; Khaled M. Kebaish, MD12; Christopher I. Shaffrey, MD9; Shay Bess, FDA Device/Drug Status: This abstract does not discuss or include any MD13; International Spine Study Group14 applicable devices or drugs.

3:52–3:59 p.m.

2. The re-herniation after decompression (RAD) 1Los Angeles, CA, US; 2Thomas Jefferson University, Philadelphia, PA, US; score identifies patients at low-risk for re- 3Midwest Orthopedics at Rush, Chicago, IL, US; 4Queen Mary Hospital, herniation after lumbar decompression surgery Hong Kong, Hong Kong; 5Rush University Medical Center, Department of Orthopedic Surgery, Chicago, IL, US Garrett Harada, MD1; Bryce Basques, MD, MHS2; Alexander Hornung, BS3; Dino Samartzis, ScD, PhD, FDA Device/Drug Status: This abstract does not discuss or include any MSc4; Howard S. An, MD5 applicable devices or drugs.

3:59–4:06 p.m.

3. Global Spine Outreach (GSO): how to safely 1Scripps Clinic Medical Group, Department of Orthopedics, La Jolla, CA, establish a sustainable short-term spine US; 2San Diego, CA, US; 3Global Spine Outreach, Nashville, TN, US deformity outreach program FDA Device/Drug Status: This abstract does not discuss or include any Gregory M. Mundis Jr., MD1; Fernando Rios, MD2; applicable devices or drugs. Lesley Mundis, PA-C2; Melissa Hicks3

4:06–4:13 p.m.

4. At what point should the thoracolumbar 1NY Spine Institute, NYU Langone Health, New York, NY, US; 2NYU Spine region be addressed in patients undergoing Research Lab, New York, NY, US; 3Hospital for Special Surgery, New York, corrective cervical deformity surgery? NY, US; 4UC, Davis School of Medicine, Sacramento, CA, US; 5Department of Orthopaedic Surgery, SUNY Downstate Medical Center, Brooklyn, NY, Peter G. Passias, MD1; Katherine E. Pierce, BS2; US; 6Department of Orthopaedic Surgery, NYU Langone Orthopaedic Virginie Lafage, PhD3; Renaud Lafage, MSc3; Eric O. Hospital, NYU Langone Health, New York, NY, US; 7University of Pittsburgh Klineberg, MD4; Bassel G. Diebo, MD5; Themistocles School of Medicine, Pittsburgh, PA, US; 8Department of Orthopaedic S. Protopsaltis, MD6; D. Kojo Hamilton, MD7; Shaleen Surgery, UT Southwestern Medical Center, Dallas, TX, US; 9Denver N. Vira, MD8; Breton Line, BS9; Robert A. Hart, MD10; International Spine Center, Denver, CO, US; 10Swedish Neuroscience Douglas C. Burton, MD11; Shay Bess, MD12; Frank J. Institute, Seattle, WA, US; 11University of Kansas Medical Center, Kansas Schwab, MD3; Christopher I. Shaffrey, MD13; Justin City, KS, US; 12Denver, CO, US; 13Duke University, Durham, NC, US; 14UVA S. Smith, MD, PhD14; Christopher P. Ames, MD15; Health System, Charlottesville, VA, US; 15University of California, San International Spine Study Group16 Francisco, San Francisco, CA, US; 16Brighton, CO, US FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. Wednesday, October 7 24

4:13–4:20 p.m.

5. Are octogenarians at higher risk for 1Southern California Permanente Medical Group, Los Angeles, CA, US; 2San complications after elective lumbar spinal fusion Diego, CA, US; 3Kaiser Permanente, San Diego, CA, US; 4Kaiser Permanente, surgery compared with younger patients? A Oakland, CA, US study from the Kaiser Permanente National FDA Device/Drug Status: This abstract does not discuss or include any Spine Registry applicable devices or drugs. T. Kent Ganocy II, MD1; Kathryn Royse, PhD, MPH2; Heather Prentice, PhD, MPH3; Jessica E. Harris, MS3; Calvin C. Kuo, MD4 4:20–4:27 p.m.

6. PLF or ALIF+PS: Which has a lower operative 1Kaiser Permanente, Los Angeles, CA, US; 2San Diego, CA, US; 3Southern nonunion rate? Analysis of a cohort of 2,061 California Permanente Medical Group, Los Angeles, CA, US; 4University of 5 patients from a national spine registry California, Davis, Sacramento, CA, US; Kaiser Permanente, San Jose, CA, 6 7 8 1 2 US; Ann Arbor, MI, US; Kaiser Permanente, San Diego, CA, US; Kaiser Elizabeth P. Norheim, MD ; Kathryn Royse, PhD, MPH ; Permanente Medical Group, Sacramento, CA, US Harsimran Brara, MD3; David J. Moller, MD4; Patrick W. Suen, MD5; Shayan Rahman, MD6; Jessica E. Harris, FDA Device/Drug Status: This abstract does not discuss or include any MS7; Kern H. Guppy, MD, PhD8 applicable devices or drugs.

4:27–4:34 p.m.

7. Mild and severe obesity reduce effectiveness 1Charlotte, NC, US; 2Carolinas Medical Center, Charlotte, NC, US; 3Carolina of lumbar fusions: one-year patient-reported Neurosurgery & Spine Associates, Charlotte, NC, US outcomes in 8,171 patients FDA Device/Drug Status: This abstract does not discuss or include any Olivia Rice, MD1; Joshua C. Patt, MD, MPH2; Anthony L. applicable devices or drugs. Asher, MD3; Matthew J. McGirt, MD3

4:34–4:45 p.m.

Discussion

4:45–5:00 p.m. Break Industry Presentation: Joimax (4:45-4:55) The Future of Spine

5:00–7:00 p.m. SURGICAL TECHNIQUE CADAVER DEMONSTRATION: Spine Deformity Surgery Faculty Presenter: Sigurd H. Berven, MD

This surgical technique cadaver Upon completion of this session, participants should gain strategies to: demonstration will provide an • Incorporate the latest techniques in complex spine surgery into their practice; overview and demonstration of • Determine concepts and principles of spinal deformity surgery as well as the spinal deformity surgery. technical considerations and surgical strategies to treat adult spinal deformity.

6:45–7:45 p.m. Industry Workshop: elliquence The Full Continuum of Least Invasive Spine Procedures

7:45–8:45 p.m. Industry Workshop: Ethicon Spine Surgery During COVID-19 Thursday, October 8 25

12:00–1:00 p.m. PLENARY SESSION: Advances and Challenges in Degenerative Cervical Myelopathy Moderators: Brian K. Kwon, MD, PhD, FRCSC; Michael G. Fehlings, MD, PhD, FRCSC; Christopher G. Furey MD; and Benjamin Davies, MbChB

DESCRIPTION AGENDA In this session, faculty will discuss the available Introduction: AOSpine and AOSpine Knowledge Forum research for degenerative cervical myelopathy (DCM) Spinal Cord Injury as well as present case discussions to address the Brian K. Kwon, MD, PhD, FRCSC challenges of DCM management. DCM: The Global Burden and Need for Knowledge Discovery Upon completion of the symposium, participants Michael G. Fehlings, MD, PhD, FRCSC should gain strategies to: Why Involve Patients and Non-Specialists in DCM • Identify the top research priorities for DCM and their Research? significance for the field of DC; Jefferson Wilson, MD, PhD, FRCSC • Recognize the minimum dataset for DCM, and its significance for the field of DCM; AOSpine RECODE-DCM: Developing a DCM Research Toolkit • Identify new opportunities to contribute to care Benjamin Davies, MbChB advances in DCM through research; AOSpine RECODE-DCM: The Top 10 Research Priorities • Approach challenges in the management of DCM Mark Kotter, MD, PhD through case discussions. Case Discussions: Challenging Issues in Degenerative Cervical Myelopathy Christopher G. Furey, MD, Sanford E. Emery, MD, MBA, Zachary Gordon, MD, William Richardson, MD, Melissa Erickson, MD Summary and Discussion Michael G. Fehlings, MD, PhD, FRCSC

1:00–1:15 p.m. Break Industry Presentation: Medtronic/Mazor (1:00-1:10) Mazor X™: The Innovation Continues Thursday, October 8 26

CONCURRENT SESSION 1:15–2:15 p.m. SECTION ON ROBOTICS AND NAVIGATION: Pushing the Frontiers of Spine Surgery through Advanced Technologies and Robotics Moderator: Chetan K. Patel, MD

DESCRIPTION AGENDA This symposium will review the latest advances in robotics, Updates in Robotic Spine Surgery navigation, and augmented reality in spine surgery. Since the Srinivas K. Prasad, MD learning curve is often a rate-limiting step in adopting new techniques and technology, we will review a new 3D printing New Application of Navigation: Navigated Endoscopy technology that helps improve this curve. Nathaniel P. Brooks, MD Simulation Using 3D Printing: Teaching and Clinical Upon completion of this session, participants should gain Applications strategies to: Eric W. Nottmeier, MD • Review the latest literature that evaluates the techniques as well as the benefits and drawbacks of using robotics in spine Is Augmented Reality the Next Frontier in Spine Surgery? surgery; Chetan K. Patel, MD • Define how navigation can be used to help facilitate performing spine endoscopy; • Describe the clinical use of augmented reality systems in spine surgery along with their clinical results; • Explain the use of a novel 3D printed system to simulate spine surgery. . Thursday, October 8 27

CONCURRENT SESSION 1:15–2:15 p.m. MEDICAL SYMPOSIUM: Muscle Health as a Biomarker for Functional Recovery Following Spine Pain and Injury Moderator: Bahar Shahidi, PT, PhD

DESCRIPTION AGENDA Faculty will address the evolving imaging and Cervical Spine: What are the Unique Features of Healthy biological-based technologies that have allowed for and Unhealthy Muscle and How Does Muscle Contribute the characterization of previously less visible micro- to Spinal Function Across the Life Span? and macroscopic features of muscle structure. While James M. Elliott, PhD, PT these technologies are fast becoming a cornerstone of Cervical Degenerative Disease precision medicine/rehabilitation, they are not meant to Zachary A. Smith, MD replace its healthcare partners, but rather to enhance clinical decision making on a patient-by-patient basis. The Lumbar Spine Bahar Shahidi, PT, PhD Upon completion of the symposium, participants should gain strategies to: • Identify spinal muscle structure, function and pathological changes in the presence of spinal disease; • Characterize the degeneration of muscle and spinal cord white matter pathways following head/neck trauma and in patients with degenerative cervical myelopathy; • Assess the impact of muscle health on pre- and post- operative outcomes; • Recognize new technologies and advancements for characterizing muscle health and their value in clinical decision-making. Thursday, October 8 28

CONCURRENT SESSION 1:15–2:15 p.m. MULTIDISCIPLINARY SYMPOSIUM: Leadership Perspective: Practical Solutions to Impact Physicians’ Professional Fulfillment Moderator: Richard L. Skolasky, ScD

DESCRIPTION AGENDA A recent systematic review identified 50 organization- Introduction to Leadership Development Program and directed workplace interventions to identify and Speakers ameliorate the effect of physician burnout, including Richard L. Skolasky, ScD stress or job satisfaction. DeChant, et al. classified these interventions into four distinct categories: Teamwork; Campfire 1: Overview of Physician Stress and Burnout Time; Transitions; and Technology. Thirty-five (70%) of Richard L. Skolasky, ScD reported interventions decreased physician burnout and Campfire 2: Professional Fulfillment: Roles of Workplace improved job satisfaction. In this symposium, participants Systems, Culture and Individuals will hear a recognized leader discuss interventions that Susan J. Rehm, MD address physician wellness and fulfillment, discuss lessons learned and next steps, and understand how to Developing Action Plans, Next Steps incorporate this approach in their healthcare setting. Susan J. Rehm, MD and Richard L. Skolasky, ScD

Upon completion of the symposium, participants should gain strategies to: • Recognize the role that physician wellness plays to reduce turnover and stress, and to improve job satisfaction; • Determine interventions to improve physicians’ professional fulfillment; • Draft action plan to address professional fulfillment in your own organization.

2:15–2:45 p.m. Break Industry Presentation: EOS (2:15-2:25) Set Your Practice Apart : 2D/3DImaging Solutions for Degenerative Spine Management Industry Presentation: GE (2:25-2:35) 3D Printed Interbody Fusion Devices - Clinical Benefits Thursday, October 8 29

CONCURRENT SESSION 2:45–3:45 p.m. SECTION ON SPINAL CORD INJURY: Translational Spinal Cord Injury: Advances and Challenges Moderators: Rajiv Saigal, MD, PhD and Yi Lu, MD, PhD

DESCRIPTION AGENDA Over the past decade, there has been a flourish of novel Use of Neural Stem Cells in Spinal Cord Injury strategies to reverse the functional loss after severe Mark Tuszynski, MD, PhD spinal cord injury (SCI), ranging from stem cells, epidural stimulations, brain-machine interface, neuroplasticity Updates in Spinal Cord Injury Small Molecule Clinical enhancement, among others. Faculty will present the Trials newest and most exciting advances in translational Michael G. Fehlings, MD, PhD FRCSC spinal cord injury research, as well as discuss some of Current Status of Neural Progenitors in the Treatment of latest topics and publications. The session will provide Spinal Cord Injury opportunities to discuss some of the research in process Shekar N. Kurpad, MD, PhD and enrolling in new SCI trials. Epidural Spinal Cord Stimulation in Chronic Complete Upon completion of the symposium, participants should Spinal Cord Injury gain strategies to: Uzma Samadani, MD, PhD • Appraise their knowledge about the most recent advances Questions and Answers on translational spinal cord injury research; All Faculty • Discuss the current updates of the ongoing spinal cord injury trials; • Consider the use of stem cells and safety of cell transplantations in treatment of SCI; • Analyze the research advancement epidural stimulations and brain machine interface for SCI treatment. Thursday, October 8 30

CONCURRENT SESSION 2:45–3:45 p.m. MEDICAL SYMPOSIUM: Physiological Modifications for Cost Effectiveness and Enhanced Recovery: Enhanced Recovery After Spine Surgery (ERASS): Early Results and Implementation Moderators: Karthik Madhavan, MD; Michael P. Steinmetz, MD; Neil R. Malhotra, MD; and Sheeraz A. Qureshi, MD, MBA

DESCRIPTION AGENDA ERASS is an attempt to redesign the age-old management Introduction to ERASS and History of surgical patients based on essential physiological Karthik Madhavan, MD approaches to enhance recovery. An electronic record Results: ERASS at University of Pennsylvania system is imperative in ERASS data procurement and Zarina Ali, MD necessary modalities to translate data from EMR to your database. Results: ERASS at Miami Michael Y. Wang, MD Faculty will provide a brief history of ERASS and essential physiological modifications, present results of Results: ERASS at Stanford implemention in various universities and their respective Anand Veeravagu, MD results from these protocols. Key interventions such Importance of Thoracolumbar Fascial Block in Spine as pre-operative counselling, fluid management, Surgery carbohydrate loading on insulin resistance, strategies to Alok D. Sharan, MD, MHCDS minimize blood loss and protocols for transfusion and their outcomes in large institutions are addressed. Utilization of EMR in Data Procurement Neil R. Malhotra, MD Upon completion of the symposium, participants Panel Discussion: One Intervention You Should Not should gain strategies to: Forget • Recognize the functioning of ERAS and key All Faculty interventions; • Assess results from early protocols implantation in different institutions; • Gain insight about anesthesia protocols to minimize redundancy; • Identify IV Tylenol and liposomal bupivacaine usage in an opioid crisis; • Implement EMR incorporation for data translation. Thursday, October 8 31

CONCURRENT SESSION 2:45–3:45 p.m. MULTIDISCIPLINARY SYMPOSIUM: Section on Biologics and Basic Research: The Present and Future of Post BMP Biologics Moderators: Christopher D. Chaput, MD and Zorica Buser, PhD

DESCRIPTION AGENDA Faculty will present the types and evidence of Introduction, I-Factor and B2A osteobiologics with an emphasis on recombinant Christopher D. Chaput, MD proteins/peptides, and discuss small molecules or Nell1 and LMP Mechanism of Action: Similarity and biologics with a similar mode of action as BMP2. Differences with BMP2 By incorporating the “campfire” format, attendees Safdar N. Khan, MD can become acquainted with the cutting edge in osteobiologics while at the same time sharing their Preclinical Evidence for Nell1 and LMP: Potential Side experiences and engaging with thought leaders in the Effects and RegulatoryFuture field. Gregory D. Schroeder, MD The Importance of the Carrier Upon completion of the symposium, participants Zorica Buser, PhD should gain strategies to: • Identify new peptides and small molecule biologics for spine fusion; • Describe types of carriers and their role in the function of small molecules; • Discuss the current level of evidence, patient selection and surgical approach; • Identify potential adverse events and costs associated with each osteobiologic.

3:45–4:00 p.m. Break Industry Presentation: Vivex (3:45-3:55) Minimally Invasive Technology Viable Allogeneic Bone Matrix Thursday, October 8 32

4:00–5:00 p.m. FEATURED ABSTRACT PRESENTATION: Best Papers Moderators: Donna M. Lahey, RNFA, CNOR and Christina L. Goldstein, MD, FRCSC

4:00–4:07 p.m.

84. Low density pedicle screw constructs are 1Brown University, Alpert Medical School, Providence, RI, US; 2Hospital associated with lower incidence of proximal for Special Surgery, New York, NY, US; 3University of Pittsburgh School 4 junctional failure in adult spinal deformity of Medicine, Pittsburgh, PA, US; NY Spine Institute, NYU Langone Health, 5 surgery New York, NY, US; Department of Orthopaedic Surgery, NYU Langone Orthopaedic Hospital, NYU Langone Health, New York, NY, US; 6UVA 1 2 Wesley M. Durand ; Han Jo Kim, MD ; D. Kojo Hamilton, Health System, Charlottesville, VA, US; 7Duke University , Durham, NC, US; 3 2 4 MD ; Renaud Lafage, MSc ; Peter G. Passias, MD ; 8Washington University School of Medicine, St. Louis, MO, US; 9UC, Davis 5 Themistocles S. Protopsaltis, MD ; Virginie Lafage, School of Medicine, Sacramento, CA, US; 10Norton Leatherman Spine 2 6 PhD ; Justin S. Smith, MD, PhD ; Christopher I. Shaffrey, Center, Louisville, KY, US; 11Scripps Clinic Medical Group, Department of 7 8 9 MD ; Munish C. Gupta, MD ; Eric O. Klineberg, MD ; Orthopedics, La Jolla, CA, US; 12Scripps Clinic, San Diego, CA, US; 13Johns 2 10 Frank J. Schwab, MD ; Jeffrey L. Gum, MD ; Gregory Hopkins University, Baltimore, MD, US; 14University of Calgary, Calgary, 11 12 M. Mundis Jr., MD ; Robert K. Eastlack, MD ; Khaled Canada; 15Southwest Scoliosis Institute, Dallas, TX, US; 16University 13 14 M. Kebaish, MD ; Alexandra Soroceanu, MD, MPH ; of Kansas Medical Center, Kansas City, KS, US; 17Denver, CO, US; 15 16 Richard A. Hostin Jr., MD ; Douglas C. Burton, MD ; 18University of California, San Francisco, San Francisco, CA, US; 19Swedish 17 18 Shay Bess, MD ; Christopher P. Ames, MD ; Robert A. Neuroscience Institute, Seattle, WA, US; 20Warren Alpert Medical School of 19 20 Hart, MD ; Alan H. Daniels, MD ; International Spine BU/RI Hospital, Providence, RI, US; 21Brighton, CO, US Study Group21 FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs.

4:07–4:14 p.m.

85. Incidence and resolution strategies for early 1Center for Disc Replacement at Texas Back Institute, Plano, TX, US; onset postoperative leg pain following lumbar 2Texas Back Institute Research Foundation, Plano, TX, US; 3Cornerstone total disc replacement Research Group, Burlington, ON, Canada; 4Eversana, Burlington, ON, Canada Richard D. Guyer, MD1; Scott L. Blumenthal, MD1; Donna D. Ohnmeiss, PhD1,2; Nicole Ferko, MSc3; Ashley FDA Device/Drug Status: activL and ProDisc-L (Approved for this Bonner, PhD4; Aaron Situ, MSc, BS4 indication)

4:14–4:21 p.m.

86. Why are DBMs so variable? Influence of 1Scripps Clinic Medical Group, Department of Orthopedics, La Jolla, CA, US; fibers, carrier, and tissue bank 2Carlsbad, CA, US; 3Surgical and Orthopaedic Research Labs, Randwick, Maroubra, ; 4SeaSpine Orthopedics, Carlsbad, CA, US; 5SeaSpine, Gregory M. Mundis Jr., MD1; Nick Russell, PhD2; William Carlsbad, CA, US Walsh, PhD3; Peter Kim, MS4; Jennifer Chen, PhD5; Frank Vizesi, PhD, PhD5 FDA Device/Drug Status: Grafton (Approved for this indication), DBX Putty (Approved for this indication), Optium Putty (Approved for this indication)

4:21–4:28 p.m.

87. Rates of loosening, failure, and revision of 1Scripps Clinic, San Diego, CA, US; 2University of Calgary, Calgary, Canada; iliac fixation in adult deformity surgery 3Scripps Clinic Medical Group, Department of Orthopedics, La Jolla, CA, US; 4Warren Alpert Medical School of BU/RI Hospital, Providence, RI, US; Robert K. Eastlack, MD1; Alexandra Soroceanu, MD, 5UVA Health System, Charlottesville, VA, US; 6Denver International Spine MPH2; Gregory M. Mundis Jr., MD3; Alan H. Daniels, Center, Denver, CO, US; 7NY Spine Institute, NYU Langone Health, New MD4; Justin S. Smith, MD, PhD5; Breton Line, BS6; York, NY, US; 8Spine Institute of Louisiana, Shreveport, LA, US; 9Pittsburgh, Peter G. Passias, MD7; Pierce D. Nunley, MD8; David O. PA, US; 10Duke University, Durham, NC, US; 11Barrow Neurological Institute, Okonkwo, MD9; Khoi D. Than, MD10; Juan S. Uribe, MD11; Phoenix, AZ, US; 12University of California San Francisco, San Francisco, Dean Chou, MD12; Khaled M. Kebaish, MD13; Christopher CA, US; 13Johns Hopkins University, Baltimore, MD, US; 14Duke University, I. Shaffrey, MD14; Shay Bess, MD15; International Spine Durham, NC, US; 15Denver, CO, US; 16Brighton, CO, US Study Group16 FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. Thursday, October 8 33

4:28–4:35 p.m.

88. Cell stiffness decreases with severity of disc 1New York, NY, US; 2The Spine Hospital, New York, NY, US; 3Columbia degeneration and inflammatory stimulation University Medical Center, New York, NY, US; 4Columbia University Medical Center, New York, NY, US; 5The Spine Hospital -Columbia University / New Nadeen Chahine, PhD1; Eric Leung, BA2; Meghan Cerpa, York Presbyterian, New York, NY, US MPH3; Meghana Vulapalli, BS4; Venkat Boddapati, MD1; Timothy Jacobsen, MEng1; Ronald A. Lehman Jr., MD5 FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs.

4:35–4:42 p.m.

89. Is academic department teaching status 1Department of Orthopedic Surgery, Long Island Jewish Medical Center, associated with adverse outcomes after lumbar New Hyde Park, NY, US; 2Northwell Health Orthopaedic Surgery, New Hyde 3 4 fusion for degenerative spine diseases? Park, NY, US; Bronx, NY, US; Northwell Health North Shore-LIJ, New Hyde 5 6 1 2 Park, NY, US; Long Island Jewish Hospital, Queens, NY, US; Great Neck, Dean C. Perfetti, MD, MPH ; Daniel Kiridly, MD, MBA ; NY, US; 7Northwell Health, Great Neck, NY, US Matthew Morris, MD3; Alan Job, MD4; Austen Katz, MD5; Jeff S. Silber, MD, DC6; David A. Essig, MD7 FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs.

4:42–4:49 p.m.

90. Nanoroughened microstructured 1VCU College of Engineering, Department of Biomedical Engineering, orthopaedic implant surfaces induce Richmond, VA, US; 2Virginia Commonwealth University, Richmond, VA, US; 3 4 osteogenesis via soluble signaling factors Medtronic (Titan Spine), Mequon, WI, US; SpineCare Medical Group, Daly 5 produced by MSCs City, CA, US; Richmond, VA, US Michael Berger, BS1; David Joshua Cohen, MD2; Kyla FDA Device/Drug Status: Interbody Fusion Implants (Approved for this Bosh2; Michelle B. Gallagher, MS3; Paul J. Slosar, MD4; indication) Zvi S. Schwartz; Barbara D. Boyan, PhD5

4:49–5:00 p.m.

Discussion

5:00–5:15 p.m. Break Industry Presentation: DePuy Synthes (5:00-5:10) DePuy Synthes Spine UNLEASH™ MIS Procedural Solution for TLIF and ATP/Lateral Thursday, October 8 34

5:15–6:45 p.m. SURGICAL TECHNIQUE CADAVER DEMONSTRATION: MIS Tubular Decompression Faculty Presenter: John C. Liu, MD

This surgical technique cadaver demonstration will Upon completion of this session, participants should provide an overview and demonstration of MIS Tubular gain strategies to: Decompression. • Incorporate the latest techniques in complex spine surgery into their practice; • Identify the nuances, advantages, and limitation of minimally invasive spine surgery.

7:00–7:30 p.m. Industry Workshop: Globus Medical The Next Evolution of ExcelsiusGPS® featuring Interbody Solutions

7:30–8:00 p.m. Industry Workshop: Globus Medical Maximizing Lordosis with Posterior MIS Approaches

8:00–9:00 p.m. Industry Workshop: DePuy Synthes Cervical Classifications, Alignment and Case Base Review Session Friday, October 9 35

12:00–1:00 p.m. PLENARY SESSION: Physicians in the Crosshairs: Government Enforcement Trends and Priorities Affecting Physicians and Physician Practices Moderator: Scott Grubman, JD, Partner, Chilivis, Grubman, Dalbey & Warner

DESCRIPTION AGENDA In 2018 alone, the federal government collected over Faculty: Scott Grubman, JD, Partner, Chilivis, Grubman, $2.5 billion from healthcare providers under the federal Dalbey & Warner False Claims Act, continuing a decades-long trend of Discussion of Relevant Statutues and Regulations multi-billion dollar recoveries. Healthcare providers face constant scrutiny from government regulators. A Discussion of Recent Examples of Enforcement former federal healthcare fraud prosecutor turned How to Build an Effective Compliance Program defense lawyer will discuss the trends and priorities in government enforcement, the major statutes and Questions and Answers regulations governing healthcare providers, as well as provide recent examples of enforcement initiatives and tips on how to stay off of the government’s radar.

Upon completion of the symposium, participants should gain strategies to: • Evaluate the major statutes and regulations governing healthcare providers; • Recognize examples of recent government enforcement initiatives in the healthcare space; • Build an effective compliance program to avoid government scrutiny.

1:00–1:15 p.m. Break Industry Presentation: Esaote (1:00-1:10) Competitive Advantage of G-Scan Brio MRI in Surgical Planning Friday, October 9 36

CONCURRENT SESSION 1:15–2:15 p.m. SURGICAL SYMPOSIUM: Endoscopic Spine Surgery: Cost, Data and Advances Moderators: Nathaniel P. Brooks, MD; Christoph P. Hofstetter, MD, PhD; and Michael P. Steinmetz, MD

DESCRIPTION AGENDA Endoscopic spine surgery is becoming more prevalent Introduction by Moderators globally. The adoption of this technology and associated Cost and Expenditure of Endoscopy and Negotiations for techniques require acquisition of new equipment and New Practice skills. The purpose of this symposium is to provide Christopher A. Yeung, MD participants with an understanding of the costs of developing an endoscopic practice, an understanding of Training Fellows and Transition to Job and Board procedure coding for endoscopic spine procedures and a Certification sample description of advanced endoscopic procedures. Cristoph P. Hofstetter, MD, PhD Finally, in the interest of education and entertainment, Endoscopy in ASC: My First 10 Cases faculty will debate the adoption of endoscopic procedures. Daniel T. Laich, DO

Upon completion of the symposium, participants should Advanced Technique: Robotics, Navigation, and gain strategies to: Endoscopy on the Spine Jin-Sung Luke Kim, MD, PhD • Evaluate the cost of developing an endoscopy practice; Advanced Technique: Laser and Endoscopic Spine • Negotiate for a spine surgeon transitioning to residency Surgery regarding developing endoscopy; Choll W. Kim, MD, PhD • Implement endoscopy in ambulatory care surgery; Coding for Advanced Endoscopic Techniques • Incorporate newer technology (LASER) and robotics in Albert E. Telfeian, MD, PhD combination with endoscopy. Debate A: Endoscopy is the Best Thing Ever Nathaniel P. Brooks, MD Debate B: Endoscopy is a Fad Michael P. Steinmetz, MD Rebuttal Nathaniel P. Brooks, MD Verdict, Questions and Answers Karthik Madhavan, MD

CONCURRENT SESSION 1:15–2:15 p.m. MEDICAL SYMPOSIUM: Sections on Comprehensive Episodes of Spine and Interventional Spine & Musculoskeletal Medicine (ISMM): Disc and Vertebrogenic Pain Moderator: Alison A. Stout, DO

DESCRIPTION AGENDA Faculty will discuss disc mechanics and discography, as Disc and Vertebrogenic Pain: Anatomy, Innervation well as review the evidence for intradiscal biologics and and Mechanics provide an overview of basivertebral nerve (BVN) ablation. Matthew Smuck, MD

Upon completion of the symposium, participants Discography should gain strategies to: Zachary McCormick, MD • Recognize disc mechanics; Intradiscal Biologics: A Review of the Evidence • Identify the evidence for intradiscal biologics; Byron J. Schneider, MD • Gain insight about basivertebral nerve (BVN) ablation to Basivertebral Nerve Ablation for Axial Lumbar Pain: treat back pain. Limitations and Promise Alison A. Stout, DO Friday, October 9 37

CONCURRENT SESSION 1:15–2:15 p.m. MULTIDISCIPLINARY SYMPOSIUM: Artificial Intelligence and Machine Learning in Spine Surgery Moderators: Aditya V. Karhade, MD and Joseph H. Schwab, MD

DESCRIPTION AGENDA Faculty will address predictive modeling for prognosis Introduction and diagnosis in spine care, applications of deep learning Joseph H. Schwab, MD and natural language processing, as well as guidelines Principles of Predictive Modeling in Spine Surgery and best practices for development and use of machine Michiel Bongers, MD learning and artificial intelligence tools in spine surgery. Deep Learning in Spine Surgery Upon completion of the symposium, participants should Aditya V. Karhade, MD gain strategies to: Natural Language Processing in Spine Surgery • Identify core principles of machine learning for Olivier Groot, MD prognosis and diagnosis in spine care; Emerging Areas of Artificial Intelligence for Future • Review recent progress in applications of deep learning Translation to Spine Surgery and natural language processing for spine surgery; Jacobien Oosterhoff, MD; Hamid Ghaednia, MD • Evaluate guidelines and best practices for development Review and Conclusion and use of machine learning tools in spine surgery; Joseph H. Schwab, MD • Pinpoint emerging areas of artificial intelligence for future translation to spine surgery. Questions and Answers All faculty

2:15–2:44 p.m. Members’ Business Meeting

2:30–3:40 p.m. FEATURED ABSTRACT PRESENTATION: Best Papers Moderator: Saeed Khayatzadeh, PhD

2:30–2:37 p.m.

155. Safer way for vertebroplasty under fluid 1Institute of Biomedical Engineering, National Taiwan University, Taipei, mechanics theory Taiwan; 2Department of Orthopedic Surgery, National Taiwan University Hospital, Hsin-Chu Biomedical Park Branch, Taipei, Taiwan; 3Department Hsuan Yu Chen, MD1,2; Yen-Po Lin, MD3; Han Ying of Orthopedic Surgery, National Taiwan University Hospital, Hsin-Chu Wang, MD3; Feng Huei Lin, PhD1; Po-Quang Chen, MD, Branch, Taipei, Taiwan; 4Department of Orthopedic Surgery, Natinal Taiwan PhD4; Ding-cheng Chan, MD, PhD, FACP5; Tze Hong University Hospital, Taipei, Taiwan; 5National Taiwan University Hospital Wong, MD, PhD3; Ming-Hsiao Hu, MD, PhD4 Chu-Tung Branch, Hsinchu County, Taiwan FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. Friday, October 9 38

2:37–2:44 p.m.

1 2 156. Operative vs. nonoperative treatment for UVA Health System, Charlottesville, VA, US; Washington University 3 adult symptomatic lumbar scoliosis at 5-6-year in St. Louis, St. Louis, MO, US; Washington University, Department of Orthopedics, St. Louis, MO, US; 4University of Virginia Neurosurgery, follow-up: outcomes and impact of related Charlottesville, VA, US; 5Dartmouth College, Lebanon, NH, US; 6Baltimore, serious adverse events MD, US; 7Norton Leatherman Spine Center, Louisville, KY, US; 8Hospital Justin S. Smith, MD, PhD1; Michael P. Kelly, MD; for Special Surgery, New York, NY, US; 9Washington University School of Elizabeth Yanik, PhD, MSc2; Christine R. Baldus, RN3; Medicine, Saint Louis, MO, US; 10Toronto Western Hospital, Toronto, ON, Thomas Buell, MD4; Jon D. Lurie, MD, MS5; Charles Canada; 11Washington University School of Medicine, St. Louis, MO, US; Edwards Sr., MD6; Steven D. Glassman, MD7; Lawrence 12University of California, San Francisco, San Francisco, CA, US; 13Denver, G. Lenke, MD17; Oheneba Boachie-Adjei, MD8; Jacob CO, US; 14Duke University, Durham, NC, US; 15Washington University In M. Buchowski, MD, MS9; Leah Y. Carreon, MD, MSc7; St. Louis School of Medicine, Saint Louis, MO, US; 16Brighton, CO, US; Charles H. Crawford III, MD7; Stephen J. Lewis, MD10; 17Columbia University Department of Orthopedic Surgery, New York, NY, US Stefan Parent, MD; Virginie Lafage, PhD8; Munish 11 8 FDA Device/Drug Status: This abstract does not discuss or include any C. Gupta, MD ; Han Jo Kim, MD ; Christopher P. applicable devices or drugs. Ames, MD12; Shay Bess, MD13; Frank J. Schwab, MD8; Christopher I. Shaffrey, MD14; Keith H. Bridwell, MD15; International Spine Study Group16

2:44–2:51 p.m.

157. Do cells matter? In vitro and in vivo analysis 1Scripps Clinic Medical Group, Department of Orthopedics, La Jolla, CA, of autograft viability US; 2SeaSpine, Carlsbad, CA, US; 3Carlsbad, CA, US Gregory M. Mundis Jr., MD1; Frank Vizesi, PhD, PhD2; FDA Device/Drug Status: This abstract does not discuss or include any Nick Russell, PhD3; Jiawei He, PhD2 applicable devices or drugs.

2:51–2:58 p.m.

158. The effects of a single injection of NTG-101 1Dept of Surgery, Univ of Toronto, Toronto, ON, Canada; 2Notogen, Toronto, upon neurotrophin expression in a canine model ON, Canada of degenerative disc disease FDA Device/Drug Status: This abstract does not discuss or include any William Mark Erwin, DC, PhD1; Ajay Matta, PhD2; applicable devices or drugs. Muhammad Zia Karim, DVM2; Hoda Gerami, BS2; Bettina Zoe Benigno, BS2

2:58–3:05 p.m.

159. Efficacy of surgical decompression in 1Combined Neurosurgery and Orthopaedic Spine Program, University patients with cervical spondylotic myelopathy of British Columbia, Vancouver, BC, Canada; 2Department of Clinical results of the Canadian prospective multi-center Neurosciences, Division of Neurosurgery, Department of Radiology, study Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada; 3Department of Surgery, Section of Orthopaedics and Neurosurgery, 1 2 Mohammed Karim, MD ; Bradley Jacobs, MD, FRCSC ; University of Manitoba, Winnipeg, MB, Canada; 4Department of Surgery, 3 Michael G. Johnson, MD, FRCSC ; Christopher S. Bailey, Western University, , ON, Canada; 5Division of Neurosurgery, 4 5 MD, FRCSC ; Sean D. Christie, MD ; Jérôme Paquet, Dalhousie University, Halifax, NS, Canada; 6Department of Orthopaedics, 6 7 MD, FRCSC ; Andrew Nataraj, MSc, MD, FRCSC ; David Centre Hospitalier Universitaire de Quebec, Quebec, QC, Canada; 7Division 2 W. Cadotte, MD, PhD ; Jefferson Wilson, MD, PhD, of Neurosurgery, Faculty of Medicine and Dentistry, University of Alberta, 8 9 FRCSC ; Neil A. Manson, MD, FRCSC ; Hamilton Hall, Edmonton, Alberta, Canada; 8Divison of Neurosurgery, Department 10 2 MD, FRCSC ; Kenneth C. Thomas, MD, FRCS ; Raja of Surgery, University of Toronto, Toronto, ON, Canada; 9Canada East 11 12 Y. Rampersaud, MD, FRCSC ; Greg McIntosh, BS ; Spine Centre, Saint John Regional Hospital, Saint John, NB, Canada; 1 Charles G. Fisher, MD, FRCSC, MHS ; Nicolas Dea, MD, 10Department of Surgery, University of Toronto, Toronto, ON, Canada; 1 MSc, FRCSC 11Division of Orthopaedic Surgery and Neurosurgery, Department of Surgery, University of Toronto, Toronto, ON, Canada; 12Canadian Spine Society, Toronto, ON, Canada FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. Friday, October 9 39

3:05–3:12 p.m.

160. Fusion for fracture has no place in a lumbar 1The Ohio State University Wexner Medical Center, Columbus, OH, US; fusion bundled payment model: an analysis of 2Columbus, OH, US Medicare beneficiaries FDA Device/Drug Status: This abstract does not discuss or include any Azeem T. Malik, MBBS1; Khaled Himed, BS2; Joseph applicable devices or drugs. Drain, MD2; Elizabeth Yu, MD2; Jeffery Kim, MD1; Safdar N. Khan, MD1

3:12–3:19 p.m.

161. Cervical disc replacement using a PEEK-on- 1Center for Disc Replacement at Texas Back Institute, Plano, TX, US; ceramic implant: prospective data from seven 2Carolina Neurosurgery & Spine Associates, Charlotte, NC, US; 3Texas 4 sites participating in an FDA IDE trial for single- Spine Consultants, Addison, TX, US; Indiana Spine Group, Carmel, IN, US; 5 6 level surgery NorthShore University HealthSystem, Evanston, IL, US; Spine Institute St. John’s Health Center, Los Angeles, CA, US; 7Texas Back Institute Research 1 2 Richard D. Guyer, MD ; Domagoj Coric, MD ; Cameron Foundation, Plano, TX, US N. Carmody, MD3; Rick C. Sasso, MD4; Michael J. Musacchio, MD5; Hyun W. Bae, MD6; Donna D. FDA Device/Drug Status: Simplify (Investigational/Not approved) Ohnmeiss, PhD7

3:19–3:26 p.m.

162. Two-level cervical disc replacement using 1Carolina Neurosurgery & Spine Associates, Charlotte, NC, US; 2Center for a PEEK-on-ceramic device: prospective outcome Disc Replacement at Texas Back Institute, Plano, TX, US; 3Spine Institute 4 data from an FDA IDE trial of Louisiana, Shreveport, LA, US; The Orthopaedic Institute of Western Kentucky, Paducah, KY, US; 5Texas Back Institute, Plano, TX, US Domagoj Coric, MD1; Richard D. Guyer, MD2; Pierce D. Nunley, MD3; K. Brandon Strenge, MD4; Donna D. FDA Device/Drug Status: Simplify disc (Investigational/Not approved) Ohnmeiss, PhD5

3:26–3:33 p.m.

163. Predicting severe clinically relevant distal 1NY Spine Institute, NYU Langone Health, New York, NY, US; 2NYU Langone junctional kyphosis development following Hospital, New York NY, US; 3Hospital for Special Surgery, New York, NY, 4 adult cervical deformity surgery with further US; Department of Orthopaedic Surgery, SUNY Downstate Medical Center, 5 distinction from mild asymptomatic episodes Brooklyn, NY, US; Department of Orthopaedic Surgery, NYU Langone Orthopaedic Hospital, NYU Langone Health, New York, NY, US; 6Scripps 1 2 Peter G. Passias, MD ; Sara Naessig, BS ; Virginie Clinic, San Diego, CA, US; 7University of Calgary, Calgary, Canada; 8UC, 3 3 Lafage, PhD ; Renaud Lafage, MSc ; Bassel G. Diebo, Davis School of Medicine, Sacramento, CA, US; 9Swedish Neuroscience 4 5 MD ; Themistocles S. Protopsaltis, MD ; Han Jo Kim, Institute, Seattle, WA, US; 10University of Kansas Medical Center, Kansas 3 6 MD ; Robert K. Eastlack, MD ; Alexandra Soroceanu, City, KS, US; 11Denver, CO, US; 12Duke University , Durham, NC, US; 13UVA 7 8 9 MD, MPH ; Eric O. Klineberg, MD ; Robert A. Hart, MD ; Health System, Charlottesville, VA, US; 14University of California, San 10 11 Douglas C. Burton, MD ; Shay Bess, MD ; Frank J. Francisco, San Francisco, CA, US; 15Brighton, CO, US Schwab, MD3; Christopher I. Shaffrey, MD12; Justin S. Smith, MD, PhD13; Christopher P. Ames, MD14; FDA Device/Drug Status: This abstract does not discuss or include any International Spine Study Group15 applicable devices or drugs.

3:33–3:40 p.m.

Discussion Friday, October 9 40

3:40–3:45 p.m. Break

3:45–4:45 p.m. SURGICAL TECHNIQUE CADAVER DEMONSTRATION: Cervical Spine Surgery Faculty Presenter: Rick C. Sasso, MD

This surgical technique cadaver demonstration will provide Upon completion of this session, participants should an overview and demonstration of cervical spine surgery. gain strategies to: • Incorporate the latest techniques in complex spine surgery into their practice; • Identify the nuances, advantages, and limitation of cervical spine surgery.

4:45–5:00 p.m. Wrap-Up/Thank You Moderator: William J. Sullivan, MD OnDemand 41

SURGICAL SYMPOSIUM SURGICAL SYMPOSIUM Oblique Lumbar Interbody Fusion—Why is it AOSpine NA: Failed Back Surgery Syndrome Better? Moderators: John G. DeVine, MD and Richard J. Moderator: Chirag A. Berry, MD, MBBS, MS Bransford, MD

In this symposium, faculty will discuss the pearls and Faculty will define failed back surgery syndrome (FBSS), pitfalls of the oblique anterolateral approach, commonly address the work-up to rule out other causes of persistent referred to as oblique lumbar interbody fusion (OLIF) or symptoms after surgery, discuss the pitfalls in the work- anterior-to-psoas (ATP) approach, which utilizes an oblique up and treatment, review the evidence for conservative trajectory to provide pre-psoas retroperitoneal access to care, and identify patients that may benefit from the lumbar spine for interbody fusion. Participants will neuromodulation. take home valuable points regarding the advantages of this technique vs. anterior (ALIF) and lateral lumbar Upon completion of the symposium, participants should interbody fusion (LLIF). Additionally, faculty will present gain strategies to: a detailed discussion of potential complications and • Define failed back surgery syndrome and the provide strategies to reduce their occurrence and discuss the the work-up to exclude other causes of persistent anatomic challenges and the value provided by approach symptoms after spine surgery; surgeons for potential and new adopters of this technique. Variations and modifications of the approach, and • Discuss the pitfalls in the work-up and treatment of additional learning curve when approaching L5-S1 are also FBSS; reviewed. • Institute conservative care based on the current evidence for FBSS; Upon completion of the symposium, participants should • Indicate the patients that may benefit from gain strategies to: neuromodulation for FBSS. • Identify the evolution and anatomic basis of the oblique anterolateral approach; AGENDA • Discuss the advantages and potential pitfalls of the Failed Back Surgery Syndrome: What is it? oblique technique; Brandon D. Lawrence, MD • Review the different variations of the technique and Pitfalls in the Work-up and Treatment approach; Daniel E. Gelb, MD • Assess the special anatomic considerations when Failed Back Surgery Syndrome: Evidence for including L5-S1 in the fusion. Conservative Care Eric O. Klineberg, MD AGENDA Failed Back Surgery Syndrome: Evidence of History of the Oblique Approach Neuromodulation Chirag A. Berry, MD, MBBS, MS Daniel M. Sciubba, MD Advantages of Staying Outside the Psoas Chadi Tannoury, MD Do I Need an Approach Surgeon? Neel Anand, MD Tubes or Blade Retraction? Richard Hynes, MD Pitfalls and Complication Avoidance Tony Tannoury, MD L5-S1 Inclusion: Anatomic Challenges Chirag A. Berry, MD, MBBS, MS OnDemand 42

SURGICAL SYMPOSIUM SURGICAL SYMPOSIUM Section on Spinal Deformity: Diagnostic and Section on Intraoperative Neurophysiological Technology Innovations to Improve Safety, Monitoring: To Use, or Not to Use: That is the Outcomes and Efficiencies in Spine Deformity Question. Surgery Moderators: W. Bryan Wilent, PhD, DABNM, FASNM Moderator: Shay Bess, MD and Tara Stewart, PhD, DABNM

Technological advances in diagnostic and surgical modalities Through debate sessions, faculty will present the pros and have the potential to improve outcomes and reduce cons to facilitate decision-making regarding the utilization complications in spine deformity surgery. Faculty will review of intraoperative neurophysiological monitoring (IONM). recent innovations developed for surgical techniques and patient diagnostics to improve surgical outcomes. Upon completion of the symposium, participants should gain strategies to: Upon completion of the symposium, participants should • Appreciate the variables underlying the utilization decision; gain strategies to: • Reference key relevant publications to the question; • Anaylze technological advances in spinal alignment • Feel more justified in decisions regarding the usage of assessment and surgical planning for spine deformity IONM. surgery; • Assess advances in surgical techniques and patient AGENDA management to reduce blood loss and duration of Introduction hospital stay in spine deformity surgery; W. Bryan Wilent, PhD, DABNM, FASNM and Tara Stewart, • Explore minimally invasive, image guidance, sacroiliac PhD, DABNM fixation and robotic surgical techniques for spine Debate 1: ACDFs: Should IONM be Utilized? deformity surgery; • Pro: The Severity of the Possible Risks Warrants the • Evaluate the potential of new spine diagnostic and Utilization of IONM treatment technologies to improve patient outcomes Sina Pourtaheri, MD compared to the cost increases associated with adoption • Con: The Risk of Injury is Too Low to Justify the Cost of of these technologies. IONM John Ratliff, MD AGENDA Debate 2: Lateral/Oblique Lumbar Fusions: Do I Need an Introduction IONM Team Running MEPs? Shay Bess, MD • Pro: MEPs are Critical in Avoiding Lumbar Plexus Injuries Justin W. Silverstein, PhD, CNIM Innovations in Spinal Alignment Assessment and Surgical Planning for Spine Deformity Surgery • Con: Automated EMG Alone is Sufficient for These Jason W. Savage, MD Procedures Puya Alikhani, MD Advances in Surgical Techniques to Reduce Blood Loss in Spine Deformity Surgery Debate 3: Posterior Lumbar Fusions: Is IONM Still Needed Norman B. Chutkan, MD, FACS if Using Advanced Imaging and/or Robotics? • Pro: Multimodality Monitoring is Still Needed to Reducing Hospital Stay Following Spine Deformity Surgery: Diagnose Evolving Dysfunction in Higher Risk Patients New Innovations John P. Clark III, PhD, CNIM Tony Tannoury, MD • Con: Advances in Technologies have Increased the Appropriateness of Minimally Invasive Surgery for Adult Accuracy of Pedicle Screw Placement and have Obviated Spine Deformity the Need for IONM Hani H. Mhaidli, MD, PhD Donald M. Whiting, MD, FACS Robotic Technology to Improve Safety and Work Flow in Debate 4: Spinal Cord Stimulator Implantations: Is It Better Spine Deformity Surgery to Perform Under General Anesthesia with IONM? Raymond J. Hah, MD • Pro: IONM is Just as Accurate and It’s Better for Patients Steven M. Falowski, MD Are New Technologies Cost Effective? How Can We Balance • Con: No, Awake is the Standard and Still the Best the Cost of Innovation with Sustainable Medical Economics? Method Sigurd H. Berven, MD Michael B. Furman, MD, MS Closing Comments Shay Bess, MD Closing Remarks Faculty

OnDemand 43

SURGICAL TECHNIQUE CADAVER DEMONSTRATION SURGICAL SYMPOSIUM Minimally Invasive Prone Lateral Interbody Fusion The Sacroiliac Joint: Where Does It Fit Within Faculty Presenter: Juan S. Uribe, MD Your Practice? Moderators: David W. Polly Jr., MD and Heidi Prather, DO This surgical technique cadaver demonstration will provide an overview and demonstration of minimally invasive Faculty will examine the anatomy and biomechanics lateral interbody fusion. of the SI joint, and as a possible source of pain vs. the lumbar spine and/or hip. Faculty will provide better Upon completion of this session, participants should understanding of non-surgical and surgical treatments gain strategies to: for SI joint. • Incorporate the latest techniques in minimally invasive lateral interbody fusion into their practice; Upon completion of the symposium, participants • Identify the nuances, advantages, and limitation of should gain strategies to: minimally invasive lateral interbody spine surgery. • Learn anatomy and biomechanics of the SI Joint; • Recognize the SI Joint as a possible source of pain vs. lumbar and/or hip; SURGICAL SYMPOSIUM • Use the current evidence-based SI Joint non-surgical Section on Spine Oncology: How Will an and surgical treatments. Individual Patient Do with Spine Surgery Using Predictive Models and Calculators AGENDA Moderators: Joseph H. Schwab, MD and Daniel M. Introduction Sciubba, MD David W. Polly Jr., MD and Heidi Prather, DO

Patients and providers require better tools to forecast Anatomy and Biomechanics outcomes following spine surgery on an individual Bengt Sturesson, MD, PhD basis. Using predictive models and easy-to-use clinical SI Joint Pain, Prevalence and Burden of Disease calculators that exist on the internet or mobile device Sigurd H. Berven, MD platforms, successes and complications can be predicted with better accuracy and precision. SI Joint Differential Diagnosis: Lumbar/SI/Hip Jonathan N. Sembrano, MD Upon completion of the symposium, participants should Non-Surgical Treatments gain strategies to: Heidi Prather, DO • Review types of calculators available to predict Surgical Treatments; Lateral/Posterolater/Dorsal outcomes; David W. Polly Jr., MD • Describe methods by which outcomes can be measured; The SI Joint in Deformity Correction • Integrate calculators into clinical practice. David W. Polly Jr., MD and Peter G. Whang, MD, FACS

AGENDA Closing Remarks David W. Polly Jr., MD and Heidi Prather, DO Introduction and Presentation of Cases Daniel M. Sciubba, MD Methodology and Platforms for Predictive Modeling Joseph H. Schwab, MD Presentation of Various Available Calculators: Length of Stay to Survival Daniel M. Sciubba, MD Calculator Workshop: Using Calculators on My Own Patients Matthew L. Goodwin, MD, PhD, FACSM Conclusion and Future Directions Joseph H. Schwab, MD

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SURGICAL SYMPOSIUM RESIDENT AND FELLOW EDUCATION PATHWAY Perioperative Optimization in Adult Spinal Career Building Symposium Deformity Moderator: Andrew J. Schoenfeld, MD Moderators: Jason W. Savage, MD and Raymond J. Hah, MD The fellowship match process may be daunting. Faculty will provide insight to follow best practices and know The surgical treatment of adult spinal deformity (ASD) has which actions to avoid in the fellowship interview match been shown to improve function and PROs. Unfortunately, process (come prepared with questions). In addition, there is significant morbidity associated with surgery faculty will address approaches that can allow candidates for ASD. Perioperative optimization has been shown to to be competitive in the match. Career advancement decrease risks and improve clinical outcomes in this opportunities, via the presentation of abstracts, research patient population. papers and presentations also will be addressed.

Upon completion of the symposium, participants should Upon completion of this symposium, participants should gain strategies to: gain strategies to: • Discuss the importance of perioperative optimization in • Follow best practices and know which actions to avoid ASD surgery; in the fellowship interview and match process; • Review the evaluation and management of osteoporosis • Identify key approaches that can allow candidates to be in the ASD patient; competitive in the match; • Examine the role of predictive modeling and risk • Plan career advancement through the preparation of stratification in the treatment of ASD; abstracts, research papers and presentations. • Define frailty and its impact on the treatment ofpatients AGENDA with ASD. Abstracts, Papers and Presentations AGENDA Andrew J. Schoenfeld, MD Introduction Advice for the Fellowship Match/Evaluating Programs Jason W. Savage, MD Saad B. Chaudhary, MD, MBA The Importance of Perioperative Optimization in Adult Interacting with NASS Spinal Deformity Surgery Elizabeth Yu, MD Jason W. Savage, MD Evaluation and Management of Osteoporosis in the Adult Spinal Deformity Patient Paul A. Anderson, MD Risk Stratification and Predictive Modeling in Adult Spinal Deformity Christopher P. Ames, MD Frailty and Its Impact on the Surgical Treatment of Adult Spinal Deformity Sigurd H. Berven, MD Closing Remarks Raymond J. Hah, MD OnDemand 45

RESIDENT AND FELLOW EDUCATION PATHWAY RESIDENT AND FELLOW EDUCATION PATHWAY Coding for Residents and Fellows Transition to Practice: Landing a Job Moderator: Andrew J. Schoenfeld, MD Moderator: Andrew J. Schoenfeld, MD

In this symposium, faculty will provide a comprehensive The transition from training to practice can be one of the introduction to one of most essential skills when starting most daunting and critical periods in the life of a physician. clinical practice: an effective and working understanding of From finding a job, negotiating opportunities for success, surgical procedure and office- based coding. clinical and practice-based challenges, there are pitfalls present at every turn. Faculty will ease some of the anxiety Upon completion of this symposium, participants should and provide insight into navigating the period spanning gain strategies to: the end of clinical training and the start of independent • Effectively code surgical procedures in the cervical practice. Ideal for residents, fellows and individuals within thoracic and lumbar spine; the first five years of clinical practice, this session will cover useful information for all interested parties and • Effectively code office-based evaluation and non- those also looking to transition to a new position in the operative procedural care; near future. • Avoid pitfalls and coding violations. Upon completion of this symposium, participants should AGENDA gain strategies to: Introduction/ Office Coding and Documentation • Recognize best practices and actions to avoid in the job Andrew J. Schoenfeld, MD search, interview and negotiating process; Surgical Coding and Documentation: Cervical Procedures • Know key steps in the development of a clinical practice Saad B. Chaudhary, MD, MBA and networking within the local and national medical community; Surgical Coding and Documentation: Thoracic and Lumbar Procedures • Describe pitfalls that can interfere with a successful Sandeep N. Gidvani, MD transition from training to practice. Coding Pitfalls AGENDA William F. Lavelle, MD Finding a Job Khoi D. Than, MD Academic Positions Saad B. Chaudhary, MD, MBA Community Positions Sandeep N. Gidvani, MD Pitfalls Avery L. Buchholz, MD, MPH Negotiating Andrew J. Schoenfeld, MD Overview of Employment Contracts Sandeep N. Gidvani, MD OnDemand 46

MEDICAL SYMPOSIUM MEDICAL SYMPOSIUM Perioperative Spinal Cord Injury Ambulatory Care Surgery Practice and Moderators: Michael G. Fehlings, MD, PhD, FRCSC and Applications: Spine Surgery in the Ambulatory Christoph P. Hofstetter, MD, PhD Care Setting: Getting Patients Home Happy Moderator: Michael P. Steinmetz, MD Perioperative spinal cord injury is a well-described possible adverse outcome of spine surgery. In particular, surgeries This symposium is for spine surgeons considering an such as deformity surgery, tumor surgery and revision ambulatory surgical center (ASC) practice in the near surgeries are associated with the risk of transient or future. Early ASC adopters will provide an overview of permanent spinal cord dysfunction. In this symposium, ambulatory centers and their unique logistics, discuss faculty will discuss some of latest topics and publications. the hospital/ASC collaboration pros and cons, and This will abreast the clinicians and researchers alike as address the common procedures performed in ASC and well as provide opportunities to discuss some of the procedures to dodge. research they are working on. Upon completion of the symposium, participants should Upon completion of the symposium, participants should gain strategies to: gain strategies to: • Recognize pros and cons of working in ASC; • Identify surgeries that are prone to iatrogenic spinal cord injury; • Distinguish ASC vs. hospital-based practice vs. half-n- half; • Describe intraoperative maneuvers to avoid injury; • Identify reimbursement patterns for Medicare and • Determine the utility of electrophysiological monitoring; private insurance; • Acknowledge the rational underlying optimal • Adopt ASC in practice; hemodynamic management. • Determine common surgeries performed in ASC and exit AGENDA strategy.

The Pathology and Incidence of Perioperative Spinal AGENDA Cord Injury Michael G. Fehlings, MD, PhD, FRCSC Overview of ASC Karthik Madhavan, MD Strategies to Avoid Spinal Cord Injury in Patients with Unstable Spine Fractures Discrepancies in Reimbursement between ASC and Rajiv Saigal, MD, PhD Hospitals Scott Raffa, MD Surgical Strategies to Avoid Spinal Cord Injury in Tumor Surgery XLIF 360 and ASC Copay Christoph P. Hofstetter, MD, PhD Larry T. Khoo, MD Surgical Strategies to Avoid Spinal Cord Injury in Hospital-Based Practice: My Take On It Deformity Surgery Michael P. Steinmetz, MD Stephen J. Lewis, MD What Nerve Block Can You Do for Spine Surgery? Utility of Intraoperative Electrophysiological Monitoring Jeffrey Xu, MD Richard Vogel, PhD, DABNM Questions and Answers Optimal Hemodynamic Management during High Risk All Faculty Procedures Brian K. Kwon, MD, PhD, FRCSC

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MEDICAL SYMPOSIUM MULTIDISCIPLINARY SYMPOSIUM Transforming Your Practice with Minimally Invasive Interdisciplinary Spine Forum: Thoracic Spine Spine Care Using Evidence-Based Validation Pathology: Assessment and Differential Moderators: Kai-Uwe Lewandrowski, MD and Anthony T. Diagnosis Yeung, MD Moderators: Evan K. Johnson, PT DPT, OCS and Rick J. Placide, MD, PT This timely symposium on minimally invasive spinal (MIS) surgery techniques provides the participant with the most up- When evaluating the patient with thoracic spine to-date information on the validated indications of surgical complaints, there are unique aspects to the history, spine care. The target audience consists of well-established physical exam and differential diagnosis. Faculty practicing spine surgeons who are contemplating will review the history and exam of the patient with transitioning part of their practice away from open thoracic spine complaints, discuss the differential translaminar surgery to minimally invasive spine procedures. diagnoses in the patient with thoracic spine The symposium is aimed at those spine surgeons who complaints as well as review the regional effects the recognize the need to modernize their practice by including thoracic spine has on neighboring structures. minimally invasive and endoscopic spine surgery but are not sure how and need practical hands-on tips. Upon completion of the symposium, participants should gain strategies to: Upon completion of the symposium, participants should • Recall the elements of a history and exam in the gain strategies to: patient with thoracic spine complaints; • Acquire new information on MIS approaches and • Describe the most common differential diagnoses techniques, and skill-based knowledge on diagnostic in patients who present with thoracic spine pain; workup, indications and outcomes; • Exhibit the ability to apply knowledge of thoracic • Develop and improve knowledge on the pathologic spine mechanical dysfunction in selecting anatomy and pathophysiology of common painful treatment options; conditions of the spine; • Recognize the regional effects of thoracic spine • Formulate a plan of care employing non-operative and MIS mechanical dysfunction. surgical care based on the specific patient’s situation. AGENDA AGENDA Thoracic Spine Pain—History and Physical Exam Introduction and Welcome: Mainstreaming, Evan K. Johnson, PT DPT, OCS and Rick J. Placide, Implementation, Indications and Training Standards for MIS MD, PT Spine Care Kai-Uwe Lewandrowski, MD Medical and Surgical Lesions of the Thoracic Spine Rick J. Placide, MD, PT Indications for Endoscopic Treatment of Degenerative Conditions of the Lumbar Motion Segment: The Mechanical Thoracic Dysfunction Pathoanatomy and Physiology of Common Pain Generators Evan K. Johnson, PT DPT, OCS Anthony T. Yeung, MD Regional Considerations when Treating Thoracic

Evidence-Based Validation and Implementation of Dysfunctions Evan K. Johnson, PT DPT, OCS Clinical Protocols Employing Prognosticators of Successful Outcomes with Novel MIS Techniques Thoracic Spine Masqueraders Kai-Uwe Lewandrowski, MD Rick J. Placide, MD, PT Pushing the Limits of Endoscopic Spine Surgery in an Academic Setting Peter Shin, MD Medical Implications of Disruptive Developments in Spine Surgery Artie Eaves, Esquire Closing Summary and Post-symposium Survey Demonstration https://sitsurvey.typeform.com/to/j89Swvoh Kai-Uwe Lewandrowski, MD

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MULTIDISCIPLINARY SYMPOSIUM MULTIDISCIPLINARY SYMPOSIUM Interdisciplinary Spine Forum: The Role of Interdisciplinary Spine Forum: Treating Olympic, the First Contact and Patient Interaction in Paralympic and Elite Athletes an Attempt to Improve Prognosis and Reduce Moderator: Robb Russell, DC Chronicity in Patients with Spine Pain Moderator: David Kartzman, DC Management of sports injuries, particularly of elite athletes, is itself a team effort. In this session, participants Chronicity and poorer outcomes are fairly common in will hear from practitioners who have experience caring patients with spine pain. These patients pose a challenge for athletic spine-related pain and injuries for athletes from to spine providers and health care payment systems. In the Olympic & Paralympic Training Site in Chula Vista, this session, panel presenters will describe methods for California. Offering perspectives on physical medicine identifying key factors that may lead to chronicity and and rehabilitation, including interventional approaches, as prolonged disability. well as chiropractic care and acupuncture, this panel will provide insight into how interdisciplinary teamwork can apply to competitive and recreational athletes you may see Upon completion of the symposium, participants should in practice. gain strategies to: • Describe the importance and roles of “deep empathy” in Upon completion of the symposium, participants should initial patient interactions; gain strategies to: • Identify comorbidities which can slow recovery; • Recognize the evolution and role of interdisciplinary • Evaluate the risks for pain sensitization; spine care for elite athletes; • Make the biopsychosocial approach more tangible and • Distinguish the individual and collaborative roles of complementary to the biomedical approach; different healthcare professionals in of interdisciplinary • Recognize applicability of Keele StarT Back and Pain spine care for elite athletes; Catastrophizing Scale (PCS); • Employ information presented to assist in creating • Implement this information into our clinical decision team-based care models for interdisciplinary spine care making. of athletes.

AGENDA AGENDA Introduction Introduction David Kartzman, DC Robb Russell, DC Interview with Kush Goyal, MD USOPC, Team USA and Interdisciplinary Spine Care: Kush K. Goyal, MD and David Kartzman, DC Overview Kevin Pierce, DC Interview with Brian Justice, DC Brian Justice, DC and David Kartzman, DC Physical Medicine for Elite Athletes Kenneth Vitale, MD Interview with Christopher Bono, MD Christopher M. Bono, MD and David Kartzman, DC Physical Medicine for Elite Athletes--Interventional Considerations Wrap Up and Summary Haewon Lee, MD David Kartzman, DC USOPC, Team USA and Acupuncture for Spine Pain Jennifer Watters, DC, LAc OnDemand 49

MULTIDISCIPLINARY SYMPOSIUM MULTIDISCIPLINARY SYMPOSIUM Interdisciplinary Spine Forum: The Worksite The Future of Value-Based Healthcare in Spine Health Center—An Emerging Model and Care: A Multi-Stakeholder Perspective Opportunity in Value-Oriented Spine Care Moderators: Andrew J. Pugely, MD and Matthew J. Smith, Moderator: Claire Johnson, DC, MSEd, PhD MD, EMHL

An estimated 10 percent of the adult population under Faculty will explain fee-for-service healthcare vs. value- 65-years-old will receive their healthcare through a worksite based healthcare (VBHC) and how to participate in VBHC, health center in the next decade. Worksite health centers in addition to addressing VBHC programs and the steps to provide cost-effective, quality healthcare to employees participate in VBHC programs. at their place of employment. These clinics add value through improved health, lowered healthcare expenditures, Upon completion of the symposium, participants and improved productivity. Over half of employers with a should gain strategies to: worksite health center report a return on investment of • Describe the differences between fee-for-service 1.5 (for every dollar invested, they have saved a dollar and healthcare and value-based healthcare; a half) or higher. One-third of organizations with 5,000 or more employees provide a clinic at or near the worksite and • Identify data elements required to participate in VBHC this trend is steadily increasing. With a high prevalence (cost/quality); of spine-related disorders in the workplace, such as back • Recognize VBHC programs of today and the recent past; and neck pain, the need for integrated, worksite spine care • Appreciate perspectives from a multi-stake holder group continues to rise. Spine care providers should be familiar (physicians, hospital admin, industry, government and with this emerging model and opportunity in value-oriented commercial payors); spine care. • Learn how to take the next steps at participating in Upon completion of the symposium, participants should VBHC programs. gain strategies to: AGENDA • Identify essential components of spine care in worksite health centers; Symposium Introduction/Moderator Andrew J. Pugely, MD • Describe the clinical, cost and satisfaction data supporting worksite health centers; How Can Spine Providers Demonstrate Value? • Apply knowledge of current models and future direction Darrell Brodke, MD of spine care in worksite health centers. Government Payor Perspective: CMS/CMMI Roadmap for VBHC AGENDA Chris Ritter, PhD Spine Care and Worksite Health Centers: The Perfect Commercial Payor Perspective: United Health Care and Combination VBHC Claire Johnson, DC, MSEd, PhD Russ Amundson, MD The Importance of Spine Care in Worksite Health How VBHC Fits into Medtronic’s Mission as Med Tech Centers: A View from the National Association of Company Worksite Health Centers Sean Haag, MBA Larry Boress, MPA Integrated Provider Spine Care Teams: Experiences from Direct to Employer Health Care Contracting- The Walmart Worksite Health Centers in the Technology Sector Story Larry Kwan, MD Ruth Coleman Spine Care in an On-site Health Center: The Perspective How Hospital Systems Can Survive in a Value-Based of a Large Employer World Nicole Giczkowski Jim Weinstein, DO Essentials of Spine Care in Worksite Health Centers: A Questions and Answers Provider’s Perspective All Faculty Bart Green DC, MSEd, PhD Presentation of Case Scenarios and Panelist Responses Claire Johnson, DC, MSEd, PhD OnDemand 50

INDUSTRY PRESENTATION The TRIUMPH of BurstDR™ SCS Therapy: Sustained Improvements in Mental, Physical and Emotional Functioning Abbott

INDUSTRY PRESENTATION Tiger Woods: Reborn Centinel Spine

INDUSTRY PRESENTATION Benefits of Intraoperative Adjustments Using the ProAxis® Spinal Surgery Table Mizuho OSI

INDUSTRY PRESENTATION Improvements of Quality of Motion and Associated Patient Outcomes Orthofix

INDUSTRY PRESENTATION Complications and Treatment Options for the SI Joint SI-BONE

INDUSTRY PRESENTATION Spinal Elements Introduces MIS Ultra Spinal Elements

INDUSTRY PRESENTATION Establishing a Successful Anterior Lumbar Practice Thompson Surgical, Inc.

INDUSTRY PRESENTATION An Advanced Visualization System—ZEISS TIVATO® 700 for Spine Surgery—Learn from the Experts Zeiss Abstracts 51

NASS 35th Annual Meeting Abstracts 4. At what point should the thoracolumbar region be addressed in patients undergoing corrective cervical deformity surgery? 1. Use of ALIF at the lumbosacral junction results in less lumbopelvic fixation failure than TLIF or no interbody Peter G. Passias, MD1; Katherine E. Pierce, BS2; Virginie Lafage, fusion following correction of adult spinal deformity PhD3; Renaud Lafage, MSc3; Eric O. Klineberg, MD4; Bassel G. Diebo, MD5; Themistocles S. Protopsaltis, MD6; D. Kojo Hamilton, Robert K. Eastlack, MD1; Alexandra Soroceanu, MD, MPH2; MD7; Shaleen N. Vira, MD8; Breton Line, BS9; Robert A. Hart, MD10; Gregory M. Mundis Jr., MD3; Justin S. Smith, MD, PhD4; Breton Douglas C. Burton, MD11; Shay Bess, MD12; Frank J. Schwab, Line, BS5; Peter G. Passias, MD6; Pierce D. Nunley, MD7; David MD3; Christopher I. Shaffrey, MD13; Justin S. Smith, MD, PhD14; O. Okonkwo, MD8; Khoi D. Than, MD9; Juan S. Uribe, MD10; Dean Christopher P. Ames, MD15; International Spine Study Group16 Chou, MD11; Khaled M. Kebaish, MD12; Christopher I. Shaffrey, MD9; Shay Bess, MD13; International Spine Study Group14 1NY Spine Institute, NYU Langone Health, New York, NY, US; 2NYU Spine Research Lab, New York, NY, US; 3Hospital 1Scripps Clinic, San Diego, CA, US; 2University of Calgary, for Special Surgery, New York, NY, US; 4UC, Davis School of Calgary, Canada; 3Scripps Clinic Medical Group, Department Medicine, Sacramento, CA, US; 5Department of Orthopaedic of Orthopedics, La Jolla, CA, US; 4UVA Health System, Surgery, SUNY Downstate Medical Center, Brooklyn, NY, US; Charlottesville, VA, US; 5Denver International Spine Center, Denver, 6Department of Orthopaedic Surgery, NYU Langone Orthopaedic CO, US; 6NY Spine Institute, NYU Langone Health, New York, NY, Hospital, NYU Langone Health, New York, NY, US; 7University of US; 7Spine Institute of Louisiana, Shreveport, LA, US; 8Pittsburgh, Pittsburgh School of Medicine, Pittsburgh, PA, US; 8Department PA, US; 9Duke University, Durham, NC, US; 10Barrow Neurological of Orthopaedic Surgery, UT Southwestern Medical Center, Dallas, Institute, Phoenix, AZ, US; 11University of California San Francisco, TX, US; 9Denver International Spine Center, Denver, CO, US; San Francisco, CA, US; 12Johns Hopkins University, Baltimore, 10Swedish Neuroscience Institute, Seattle, WA, US; 11University MD, US; 13Denver, CO, US; 14Brighton, CO, US of Kansas Medical Center, Kansas City, KS, US; 12Denver, CO, FDA DEVICE/DRUG STATUS: This abstract does not discuss or US; 13Duke University, Durham, NC, US; 14UVA Health System, include any applicable devices or drugs. Charlottesville, VA, US; 15University of California, San Francisco, San Francisco, CA, US; 16Brighton, CO, US 2. The reherniation after decompression (RAD) score FDA DEVICE/DRUG STATUS: This abstract does not discuss or identifies patients at low-risk for re-herniation after include any applicable devices or drugs. lumbar decompression surgery

1 2 Garrett Harada, MD ; Bryce Basques, MD, MHS ; Alexander 5. Are octogenarians at higher risk for complications after 3 4 Hornung, BS ; Dino Samartzis, ScD, PhD, MSc ; Howard S. An, elective lumbar spinal fusion surgery compared with 5 MD younger patients? A study from the Kaiser Permanente 1Los Angeles, CA, US; 2Thomas Jefferson University, Philadelphia, National Spine Registry 3 4 PA, US; Midwest Orthopedics at Rush, Chicago, IL, US; Queen 1 2 5 T. Kent Ganocy II, MD ; Kathryn Royse, PhD, MPH ; Heather Mary Hospital, Hong Kong, Hong Kong; Rush University Medical Prentice, PhD, MPH3; Jessica E. Harris, MS3; Calvin C. Kuo, MD4 Center, Department of Orthopedic Surgery, Chicago, IL, US 1Southern California Permanente Medical Group, Los Angeles, FDA DEVICE/DRUG STATUS: This abstract does not discuss or CA, US; 2San Diego, CA, US; 3Kaiser Permanente, San Diego, CA, include any applicable devices or drugs. US; 4Kaiser Permanente, Oakland, CA, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or 3. Global Spine Outreach (GSO): how to safely establish a include any applicable devices or drugs. sustainable short-term spine deformity outreach program Gregory M. Mundis Jr., MD1; Fernando Rios, MD2; Lesley Mundis, PA-C2; Melissa Hicks3 6. PLF or ALIF+PS: which has a lower operative nonunion rate? Analysis of a cohort of 2,061 patients from a national 1Scripps Clinic Medical Group, Department of Orthopedics, spine registry La Jolla, CA, US; 2San Diego, CA, US; 3Global Spine Outreach, Nashville, TN, US Elizabeth P. Norheim, MD1; Kathryn Royse, PhD, MPH2; Harsimran Brara, MD3; David J. Moller, MD4; Patrick W. Suen, MD5; Shayan FDA DEVICE/DRUG STATUS: This abstract does not discuss or Rahman, MD6; Jessica E. Harris, MS7; Kern H. Guppy, MD, PhD8 include any applicable devices or drugs. 1Kaiser Permanente, Los Angeles, CA, US; 2San Diego, CA, US; 3Southern California Permanente Medical Group, Los Angeles, CA, US; 4University of California, Davis, Sacramento, CA, US; 5Kaiser Permanente, San Jose, CA, US; 6Ann Arbor, MI, US; 7Kaiser Permanente, San Diego, CA, US; 8Kaiser Permanente Medical Group, Sacramento, CA, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. Abstracts 52

7. Mild and severe obesity reduce effectiveness of lumbar fusions: one-year patient-reported outcomes in 8,171 11. Long-term outcomes following intraosseous patients basivertebral nerve ablation for the treatment of Olivia Rice, MD1; Joshua C. Patt, MD, MPH2; Anthony L. Asher, chronic low back pain: five-year treatment results from MD3; Matthew J. McGirt, MD3 a prospective randomized double-blind sham-controlled 1Charlotte, NC, US; 2Carolinas Medical Center, Charlotte, NC, US; multi-center study 3Carolina Neurosurgery & Spine Associates, Charlotte, NC, US Jeffrey Fischgrund, MD1; Alfred L. Rhyne, MD2; Christopher A. 3 4 5 FDA DEVICE/DRUG STATUS: This abstract does not discuss or Yeung, MD ; Eeric Truumees, MD ; D. Greg Anderson, MD ; James 6 include any applicable devices or drugs. B. Reynolds, MD 1Franklin, MI, US; 2OrthoCarolina, Charlotte, NC, US; 3Desert 4 8. Modifiable polymer promotes a pro-osteogenic, M2-like Institute for Spine Care, Phoenix, AZ, US; Seton Brain & Spine 5 macrophage phenotype and osteoblastic differentiation Institute, Austin, TX, US; Rothman Institute, Philadelphia, PA, US; 6 of progenitor cells Spine Care Medical Group, Daly City, CA, US Joseph Bartolacci1; Arthi Shridhar, PhD2; Stephen F. Badylak, FDA DEVICE/DRUG STATUS: Intracept Procedure (Approved for DVM, PhD, MD1 this indication) 1McGowan Institute for Regenerative Medicine, Pittsburgh, PA, US; 2Pittsburgh, PA, US 12. Healthcare costs and characteristics of spinal fusion patients receiving concentrated bone marrow aspirate FDA DEVICE/DRUG STATUS: ZFuze (Approved for this indication) (BMAC), iliac crest autograft or bone morphogenic protein (BMP) therapy: a retrospective cohort study utilizing 9. C5 palsy after cervical laminectomy: natural history and administrative claims risk factors in a 10-year series Ripsi Patel, MPH; Alicia Silver, MP G. Alexander Jones, MD1; Ryan Hofler, MD, MS1; Joseph Terumo BCT, Charlotte, NC, US Frazzetta, BS2; Russ P. Nockels, MD1; Amany Aziz, MD3; Jehad 1 FDA DEVICE/DRUG STATUS: This abstract does not discuss or Zakaria, MD include any applicable devices or drugs. 1Department of Neurological Surgery, Loyola University Medical Center, Maywood, IL, US; 2Loyola University Stritch School of 13. Clinical efficacy of tranexamic acid in posterolateral Medicine, Maywood, IL, US; 3Department of Radiology, Loyola lumbar fusion: a prospective, randomized controlled trial University Medical Center, Maywood, Il, US Bryce Basques, MD, MHS1; Garrett Harada, MD2; Jannat M. Khan, FDA DEVICE/DRUG STATUS: This abstract does not discuss or MD; Edward J. Goldberg, MD3; Howard S. An, MD4; Matthew include any applicable devices or drugs. Colman, MD3 1Thomas Jefferson University, Philadelphia, PA, US; 2Los Angeles, 10. Pelvic non-responders, postoperative cervical CA, US; 3Midwest Orthopedics at Rush, Chicago, IL, US; 4Rush malalignment, and proximal junctional kyphosis following University Medical Center, Department of Orthopedic Surgery, treatment of adult spinal deformity: influence of Chicago, IL, US realignment strategies on occurrence FDA DEVICE/DRUG STATUS: This abstract does not discuss or Peter G. Passias, MD1; Katherine E. Pierce, BS2; Virginie Lafage, include any applicable devices or drugs. PhD3; Renaud Lafage, MSc3; Themistocles S. Protopsaltis, MD4; 5 6 Bassel G. Diebo, MD ; Khaled M. Kebaish, MD ; Christopher P. 14. Non-linear burst spinal cord stimulation can attenuate 7 8 Ames, MD ; Justin S. Smith, MD, PhD ; Christopher I. Shaffrey, pain and catastrophizing in patients with persistent back 9 10 MD ; Douglas C. Burton, MD ; Michael P. Kelly, MD; Robert A. pain and high psychological distress Hart, MD11; Shay Bess, MD11; Frank J. Schwab, MD3; Munish C. 1 2 Gupta, MD13; International Spine Study Group14 Steven M. Falowski, MD ; Eric Cornidez, MD, MBA ; Robyn Capobianco, PhD3 1NY Spine Institute, NYU Langone Health, New York, NY, US; 1 2NYU Spine Research Lab, New York, NY, US; 3Hospital for St. Lukes University Health Network, Bethlehem, PA, US; 2 3 Special Surgery, New York, NY, US; 4Department of Orthopaedic Pain Institute of Southern Arizona, Tucson, AZ, US; Abbott Surgery, NYU Langone Orthopaedic Hospital, NYU Langone Neuromodulation, Austin, TX, US Health, New York, NY, US; 5Department of Orthopaedic Surgery, FDA DEVICE/DRUG STATUS: Spinal cord stimulation (Approved SUNY Downstate Medical Center, Brooklyn, NY, US; 6Johns for this indication) Hopkins University, Baltimore, MD, US; 7University of California, San Francisco, San Francisco, CA, US; 8UVA Health System, Charlottesville, VA, US; 9Duke University , Durham, NC, US; 10University of Kansas Medical Center, Kansas City, KS, US; 11Swedish Neuroscience Institute, Seattle, WA, US; 12Denver, CO, US; 13Washington University School of Medicine, St. Louis, MO, US; 14Brighton, CO, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. Abstracts 53

15. Use of predictive machine learning models at the 18. Fatty infiltration of the lumbar multifidus (LM) may population level has the potential to save cost by be associated with adjacent segment degeneration after directing economic resources to those likely to improve fusion for spondylolisthesis most: a simulation analysis stratified by risk in largest Ping G. Duan, PhD, MD1,3; Sigurd H. Berven, MD2; Jeremy Guinn, combined US/European ASD registry BS1; Joshua Rivera1; Dean Chou, MD1 1 2 Rushikesh S. Joshi, BS ; Miquel Serra-Burriel, PhD ; Ferran 1Department of Neurological Surgery, University of California, 2 3 4 Pellise, MD, PhD ; Darryl Lau, MD ; Justin S. Smith, MD, PhD ; San Francisco, CA, US; 2Department of Orthopaedic Surgery, 5 6 Michael P. Kelly, MD; Ahmet Alanay, MD ; Emre Acaroglu, MD ; University of California, San Francisco, CA, US; 3Department of 7 Francisco J. Perez-Grueso, MD ; Frank Kleinstuck, MD; Ibrahim Orthopaedic Surgery, The First Affiliated Hospital of Nanchang 8 8 9 Obeid, MD ; Douglas C. Burton, MD ; Virginie Lafage, PhD ; Frank University, Nanchang, China J. Schwab, MD10; Christopher I. Shaffrey, MD11; Shay Bess, MD12; Christopher P. Ames, MD13; ESSG European Spine Study Group14; FDA DEVICE/DRUG STATUS: This abstract does not discuss or International Spine Study Group15 include any applicable devices or drugs. 1Sunnyvale, CA, US; 2Barcelona, Spain; 3San Francisco, CA, US; 4UVA Health System, Charlottesville, VA, US; 5; 5Acibadem 19. Does asymptomatic human immunodeficiency virus University, School of Medicine, Istanbul, Ataşehir, Turkey; 6Ankara, (AHIV)-positive status in patients undergoing spinal Turkey; 7H. De La Paz (Madrid), Madrid, Spain; 8Bordeaux, fusion for degenerative disc disease (DDD) increase risk France; 9University of Kansas Medical Center, Kansas City, KS, for adverse postoperative outcomes? 10 11 US; Hospital for Special Surgery, New York, NY, US; Duke Neil V. Shah, MD, MS1; Matthew J. Lettieri, BA2; Ryan Scheer, BS3; 12 13 University , Durham, NC, US; Denver, CO, US University of Dillon Sedaghatpour, MD3; Brian Ford, BS3; Bassel G. Diebo, MD1; 14 California, San Francisco, San Francisco, CA, US; European Carl B. Paulino, MD3 Spine Study Group, Barcelona, Spain; 15Brighton, CO, US 1Department of Orthopaedic Surgery, SUNY Downstate Medical FDA DEVICE/DRUG STATUS: This abstract does not discuss or Center, Brooklyn, NY, US; 2Brooklyn, NY, US; 3SUNY Downstate include any applicable devices or drugs. Medical Center, Brooklyn, NY, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or 16. Is it safe to stop at C7 during multi-level posterior include any applicable devices or drugs. cervical decompression and fusion? Multi-center analysis Eeric Truumees, MD1; Devender Singh, PhD2; William F. Lavelle, 20. Achievement of optimal clinical outcomes in adult MD3; Ron I. Riesenburger, MD4; Matthew J. Geck, MD5; Swamy spinal deformity surgery requires prioritizing realignment Kurra, MD6; Anthony Yu, BS, MS; Daniel Grits, BS6; Robert goals and varies based on pelvic incidence Winkelman, BS7; Thomas E. Mroz, MD8; John Stokes, MD1 Katherine E. Pierce, BS1; Waleed Ahmad2; Sara Naessig, BS3; 1 2 Seton Brain & Spine Institute, Austin, TX, US; Ascension Texas Muhammad B. Janjua, MD4; Bassel G. Diebo, MD5; Peter G. 3 Spine and Scoliosis Center, Austin, TX, US; Upstate Orthopedics, Passias, MD6 4 East Syracuse, NY, US; Tufts University/New England Medical 1 2 5 NYU Spine Research Lab, New York, NY, US; New York, NY, Center, Boston, MA, US; Seton Spine & Scoliosis Center, Austin, 3 4 6 7 US; NYU Langone Hospital, New York NY, US; Mercy Health, TX, US; Cleveland, OH, US; Case Western Reserve University, 5 8 Rockford, IL, US; Department of Orthopaedic Surgery, SUNY Cleveland, OH, US; Cleveland Clinic Departments of Orthopaedic 6 and Neurological Surgery, Cleveland, OH, US Downstate Medical Center, Brooklyn, NY, US; NY Spine Institute, NYU Langone Health, New York, NY, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs.

17. Robotic-assisted lumbar spinal fusion surgery leads to increased risk of revision surgery, readmission, 21. The safety and efficacy of cervical laminectomy complications, and prolonged opioid utilization compared and fusion versus cervical laminoplasty surgery in to non-robotic lumbar spinal fusion surgery degenerative cervical myelopathy: a prospective randomized trial 1 2 3 Daniel Yang, BS ; Neill Li, MD ; Shyam A. Patel, MD ; Dominic T. 1 2 Kleinhenz, MD4; Alan H. Daniels, MD5 Haitham Kandel, MD ; Mohamed Soliman, PhD ; Mohamed ElMallawany, MD1; Tarek Tareef, MD, MSc, MbChB2; Ahmed 1 2 Irvine, CA, US; Brown University, Department of Orthopaedics, Elsaid, MD3; Wael El-Mahdy, MD, PhD, FRCSI4 3 Providence, RI, US; LifeSpan/Rhode Island Hospital, Providence, 1 2 4 5 Cairo University, Cairo, Egypt; Faculty of Medicine, Cairo RI, US; University Orthopedics, East Providence, RI, US; Warren 3 4 Alpert Medical School of BU/RI Hospital, Providence, RI, US University, Cairo, Egypt; Cairo, Egypt; Cairo University Medical School, Cairo, Egypt FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. Abstracts 54

22. Risk of surgical intervention is nearly normalized 26. Does anticoagulant thromboprophylaxis increase following coronary artery bypass grafting in spinal surgery bleeding complications in spinal surgery and spinal cord with key exceptions injury? A systematic review and meta-analysis Waleed Ahmad1; Joshua Bell, MD2; Katherine E. Pierce, BS3; Anh Nguyen, MD, MSc1; Sonia Tran, MBBS, MS2; Robin Turner, Sara Naessig, BS4; Frank A. Segreto, BS5; Shaleen N. Vira, MD6; PhD3; Ahmed Sadek, PhD4; Alexander S. Montgomery, FRCS5 7 8 Virginie Lafage, PhD ; Carl B. Paulino, MD ; Andrew J. Schoenfeld, 1St George’s University Hospital, London, United Kingdom; 2The 9 10 2 MD ; Bassel G. Diebo, MD ; Hamid Hassanzadeh, MD ; Peter G. Childrens Hospital at Westmead, Westmead, NSW, Australia; 12 Passias, MD 3Centre for Biostatistics, Dunedin, New Zealand; 4Wessex 1New York, NY, US; 2University of Virginia, Department of Neurological Centre, Southampton, United Kingdom; 5London, Orthopaedics , Charlottesville, VA, US; 3NYU Spine Research Lab, United Kingdom 4 New York, NY, US; NYU Langone Hospital, New York NY, US; FDA DEVICE/DRUG STATUS: low molecular weight heparin 5 NYU Langone Medical Center - Orthopaedic Hospital, Manhattan, (Approved for this indication), low dose unfractionated heparin 6 NY, US; Department of Orthopaedic Surgery, UT Southwestern (Approved for this indication) Medical Center, Dallas, TX, US; 7Hospital for Special Surgery, New York, NY, US; 8SUNY Downstate Medical Center, Brooklyn, NY, US; 9Brigham and Women’s Hospital, Boston, MA, US; 10Department 27. Efficacy of topical versus intravenous tranexamic acid of Orthopaedic Surgery, SUNY Downstate Medical Center, in pediatric spinal deformity Brooklyn, NY, US; 11NY Spine Institute, NYU Langone Health, New York, NY, US Karen Weissmann, MD1; Virginie Lafage, PhD2; Renaud Lafage, MSc2; Charles Huaiquilaf Salazar, MD3; Jonathan Elysee2; FDA DEVICE/DRUG STATUS: This abstract does not discuss or Francoise Descazeaux, MD3 include any applicable devices or drugs. 1Fundacion Medica San Cristobal, Santiago, Region Metropolitana, Chile; 2Hospital for Special Surgery, New York, NY, 23. Natural language processing for automated US; 3Santiago, Chile identification of intraoperative vascular injury in anterior lumbar spine surgery FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. Aditya V. Karhade, MD1; Michiel Bongers, MD2; Olivier Groot, MD2; Harold A. Fogel, MD2; Stuart H. Hershman, MD3; Daniel G. Tobert, MD3; Sunita Srivastava, MD3; Christopher M. Bono, MD3; James D. 28. Does baseline thoracolumbar shape influence Kang, MD4; Mitchel Harris, MD, FACS3; Joseph H. Schwab, MD3 patterns of cervical decompensation following surgical adult spinal deformity correction? 1Harvard Medical School, Boston, MA, US; 2Boston, MA, US; 3Massachusetts General Hospital, Boston, MA, US; 4Brigham and Waleed Ahmad1; Peter G. Passias, MD2; Haddy Alas, BS3; Virginie Women’s Hospital, Boston, MA, US Lafage, PhD4; Renaud Lafage, MSc4; Breton Line, BS5; Alan H. Daniels, MD6; D. Kojo Hamilton, MD7; Robert A. Hart, MD8; FDA DEVICE/DRUG STATUS: This abstract does not discuss or Douglas C. Burton, MD9; Christopher I. Shaffrey, MD10; Frank J. include any applicable devices or drugs. Schwab, MD4; Christopher P. Ames, MD11; Justin S. Smith, MD, PhD12; Shay Bess, MD13; Eric O. Klineberg, MD14; Han Jo Kim, MD4; 24. Cervical spine steroid injections for delay of surgery International Spine Study Group15 for cervical spondylotic myelopathy 1New York, NY, US; 2NY Spine Institute, NYU Langone Health, Mustfa K. Manzur, MPH, MS, BS1; Andre Samuel, MD2; Steven New York, NY, US; 3Department of Orthopedic Surgery, NYU J. McAnany, MD2; Todd J. Albert, MD2; Sravisht Iyer, MD2; Avani Langone Orthopedic Hospital, NYU Langone Health, New York, S. Vaishnav, MBBS; Catherine Himo Gang, MPH2; Sheeraz A. US; 4Hospital for Special Surgery, New York, NY, US; 5Denver Qureshi, MD, MBA2 International Spine Center, Denver, CO, US; 6Warren Alpert 7 1Thomas Jefferson University, Philadelphia, PA, US; 2Hospital for Medical School of BU/RI Hospital, Providence, RI, US; University 8 Special Surgery, New York, NY, US of Pittsburgh School of Medicine, Pittsburgh, PA, US; Swedish Neuroscience Institute, Seattle, WA, US; 9University of Kansas FDA DEVICE/DRUG STATUS: This abstract does not discuss or Medical Center, Kansas City, KS, US; 10Duke University , Durham, include any applicable devices or drugs. NC, US; 11University of California, San Francisco, San Francisco, CA, US; 12UVA Health System, Charlottesville, VA, US; 13Denver, 25. The collective influence of lumbopelvic mismatch and CO, US; 14UC, Davis School of Medicine, Sacramento, CA, US; proportional shape on clinical outcomes and proximal 15Brighton, CO, US junctional kyphosis following adult spinal deformity FDA DEVICE/DRUG STATUS: This abstract does not discuss or corrective surgery include any applicable devices or drugs. Katherine E. Pierce, BS1; Waleed Ahmad2; Sara Naessig, BS3; Bassel G. Diebo, MD4; Peter G. Passias, MD5 1NYU Spine Research Lab, New York, NY, US; 2New York, NY, US; 3NYU Langone Hospital, New York NY, US; 4Department of Orthopaedic Surgery, SUNY Downstate Medical Center, Brooklyn, NY, US; 5NY Spine Institute, NYU Langone Health, New York, NY, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. Abstracts 55

29. C2 SVA: when angles are too complicated and the 33. Utilizing predictive analytics to understand the X-ray image is too small influence of modifiable risk factors on readmission in Eric Leung, BA1; Griffin R. Baum, MD, MSc2; Zeeshan Sardar, MD, patients receiving lumbar spinal fusion MSc3; Richard P. Menger, MD4; Meghan Cerpa, MPH5; Meghana Shane Shahrestani, MS1; Alexander Ballatori, BA2; Andy Ton, BS3; Vulapalli, BS5; Joseph A. Osorio, MD, PhD6; Lawrence G. Lenke8, Xiao Chen, BA2; Jeffrey C. Wang, MD4; Zorica Buser, PhD5 7 5 MD; Ronald A. Lehman Jr, MD ; Simon Morr, MD, MPH 1Yorba Linda, CA, US; 2Los Angeles, CA, US; 3Anaheim, CA, 1The Spine Hospital, New York, NY, US; 2New York, NY, US; US; 4USC Spine Center, Los Angeles, CA, US; 5Keck School of 3NewYork-Presbyterian The Allen Hospital, New York, NY, US; Medicine, University of Southern California, Los Angeles, CA, US 4 University of South Alabama Neurosurgery, Mobile, AL, US; FDA DEVICE/DRUG STATUS: This abstract does not discuss or 5 6 Columbia University Medical Center, New York, NY, US; La Jolla, include any applicable devices or drugs. CA, US; 7The Spine Hospital -Columbia University / New York Presbyterian, New York, NY, US; 8Columbia University Department of Orthopedic Surgery, New York, NY, US 34. A novel bone cement screw system combined with vertebroplasty for the treatment of Kummell disease with FDA DEVICE/DRUG STATUS: This abstract does not discuss or bone deficiency at vertebral anterior border: minimum include any applicable devices or drugs. three-year follow-up study Biao Wang, MD1; Lingbo Kong, MD, PhD2; Dingjun Hao, MD3 30. Retrospective comparative analysis of combined vs 1 2 3 only posterior approach for treating severe scoliosis Honghui Hospital, Xi’an, Shaanxi, China; Xi’an, China; Xi’an Honghui Hospital, Xi’an, Shaanxi, China Matevž Topolovec, MD, PhD; NIkša Hero, MD, PhD FDA DEVICE/DRUG STATUS: This abstract does not discuss or Orthopaedic hospital Valdoltra, Ankaran, Slovenia include any applicable devices or drugs. FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. 35. Failure to normalize risk profile of spine fusion patients with coronary artery disease 31. A comparison of various surgical treatments for Waleed Ahmad1; Joshua Bell, MD2; Sara Naessig, BS3; Katherine cervical spondylotic myelopathy: a propensity score E. Pierce, BS4; Frank A. Segreto, BS5; Shaleen N. Vira, MD6; matched analysis Brandon P. Hirsch, MD7; Carl B. Paulino, MD8; Andrew J. Nathan J. Lee, MD1; Jun S. Kim, MD2; Paul Park, MD2; K. Daniel Schoenfeld, MD9; Bassel G. Diebo, MD10; Hamid Hassanzadeh, Riew, MD MD2; Peter G. Passias, MD11 1Columbia University, New York, NY, US; 2New York, NY, US 1New York, NY, US; 2University of Virginia, Department of 3 FDA DEVICE/DRUG STATUS: This abstract does not discuss or Orthopaedics, Charlottesville, VA, US; NYU Langone Hospital, 4 include any applicable devices or drugs. New York NY, US; NYU Spine Research Lab, New York, NY, US; 5NYU Langone Medical Center - Orthopaedic Hospital, Manhattan, NY, US; 6Department of Orthopaedic Surgery, UT Southwestern 32. Preoperative high frequency opioid use dramatically Medical Center, Dallas, TX, US; 7CORE Institute, Gilbert, AZ, US; increases complication rate within 90 days, increases 8SUNY Downstate Medical Center, Brooklyn, NY, US; 9Brigham and two-year reoperation rates, and predisposes to opioid Women’s Hospital, Boston, MA, US; 10Department of Orthopaedic dependency following adult spinal deformity correction Surgery, SUNY Downstate Medical Center, Brooklyn, NY, US; 11NY Peter G. Passias, MD1; Waleed Ahmad2; Joshua Bell, MD3; Spine Institute, NYU Langone Health, New York, NY, US Katherine E. Pierce, BS4; Sara Naessig, BS5; Frank A. Segreto, FDA DEVICE/DRUG STATUS: This abstract does not discuss or BS6; Shaleen N. Vira, MD7; Virginie Lafage, PhD8; Carl B. Paulino, include any applicable devices or drugs. MD9; Andrew J. Schoenfeld, MD10; Bassel G. Diebo, MD11; Hamid Hassanzadeh, MD3 36. Scoliosis surgery normalizes cardiac function in AIS 1 2 NY Spine Institute, NYU Langone Health, New York, NY, US; New patients York, NY, US; 3University of Virginia, Department of Orthopaedics, 1 2 3 Charlottesville, VA, US; 4NYU Spine Research Lab, New York, NY, Vishal Sarwahi, MD ; Jesse M. Galina, BS ; Rachel Gecelter ; 4 4 5 US; 5NYU Langone Hospital, New York NY, US; 6NYU Langone Aaron M. Atlas, BS ; Sayyida S. Hasan, BS ; Terry D. Amaral, MD ; 6 Medical Center - Orthopaedic Hospital, Manhattan, NY, US; Sarika Kalantre, MD 7Department of Orthopaedic Surgery, UT Southwestern Medical 1North Shore LIJ Health System, New Hyde Park, NY, US; 2New Center, Dallas, TX, US; 8Hospital for Special Surgery, New York, Hyde Path, NY, US; 3Queens, NY, US; 4Cohen Children’s Medical NY, US; 9SUNY Downstate Medical Center, Brooklyn, NY, US; Center, New Hyde Park, NY, US; 5Northwell Health, Lake Success, 10Brigham and Women’s Hospital, Boston, MA, US; 11Department NY, US; 6University Hospital of New Jersey, Newark, NJ, US of Orthopaedic Surgery, SUNY Downstate Medical Center, FDA DEVICE/DRUG STATUS: This abstract does not discuss or Brooklyn, NY, US include any applicable devices or drugs. FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. Abstracts 56

37. Outpatient minimally invasive lumbar fusion 40. Long-term radiographic outcomes following adult using multimodal analgesic management in the spinal deformity surgery ambulatorysurgery setting Amit H. Parekh, DO1; Joshua D. Schwind, MD2; Jeremy S. Smith, James Parrish, MPH1; Nathaniel Jenkins, BS, MS1; Augustus MD3; Jon I. White, MD4; Jeffrey E. Deckey, MD2 Gerald Alexander, J. Rush III, MD2; Dustin H. Massel, MD3; Nadia Hrynewycz, BS4; MD2; Edward J. Quilligan, BS5; Vance O. Gardner, MD6 3 5 1 Thomas Brundage, BS ; Jeffrey Podnar, MD ; Kern Singh, MD 1Valley Hospital, Las Vegas, NV, US; 2Orthopedic Specialty 1Rush University Medical Center, Chicago, IL, US; 2Miami, FL, US; Institute, Orange, CA, US; 3Orthopaedic Specialty Institute Medical 3Midwest Orthopaedics At Rush, Chicago, IL, US; 4Chicago, IL, US; Group of Orange County, Orange, CA, US; 4Irvine Orthopaedics, 5Park Ridge, IL, US Irvine, CA, US; 5Hoag Orthopedics Education and Research 6 FDA DEVICE/DRUG STATUS: This abstract does not discuss or Institute, Orange, CA, US; Hoag Orthopedics, Orange, CA, US include any applicable devices or drugs. FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. 38. Opioid use prior to adult spine deformity (ASD) surgery worsens postoperative outcomes and risks 41. Surgical outcomes for upper lumbar disc herniations: a continued postoperative use, independent of spine systematic review and meta-analysis of the literature deformity magnitude and type of surgery performed: a 1 2 propensity matched cohort analysis Murray Echt, MD1; Ryan Holland, MD ; Phillip Cezayirli, MD ; Rafael De la Garza Ramos, MD3; Mousa K. Hamad, MD4; Yaroslav 1 2 3 Breton Line, BS ; Shay Bess, MD ; Christopher P. Ames, MD ; J. Gelfand, MD4; Merritt Kinon, MD3; Vijay Yanamadala, MD5; Saad 4 5 Robert K. Eastlack, MD ; Gregory M. Mundis Jr., MD ; Virginie B. Chaudhary, MD, MBA6; Samuel K. Cho, MD7; Reza Yassari, MD, 6 7 8 Lafage, PhD ; Eric O. Klineberg, MD ; Munish C. Gupta, MD ; MSc4 Richard A. Hostin Jr., MD9; Douglas C. Burton, MD10; Michael 1 2 P. Kelly, MD; Khaled M. Kebaish, MD11; Frank J. Schwab, MD6; Bronx, NY, US; Albert Einstein College of Medicine/Montefiore 3 Christopher I. Shaffrey, MD12; Justin S. Smith, MD, PhD13; Medical Center, Bronx, NY, US; Montefiore Medical Center, International Spine Study Group14 Department of Neurosurgery, Spine Research Group, Bronx, NY, US; 4Montefiore Medical Center, Bronx, NY, US;5 Stamford, CT, US; 1 2 Denver International Spine Center, Denver, CO, US; Denver, CO, 6Mount Sinai Health System, New York, NY, US; 7New York, NY, US US; 3University of California, San Francisco, San Francisco, CA, US; 4Scripps Clinic, San Diego, CA, US; 5Scripps Clinic Medical FDA DEVICE/DRUG STATUS: This abstract does not discuss or Group, Department of Orthopedics, La Jolla, CA, US; 6Hospital for include any applicable devices or drugs. Special Surgery, New York, NY, US; 7UC, Davis School of Medicine, Sacramento, CA, US; 8Washington University School of Medicine, 42. Removed from Program St. Louis, MO, US; 9Southwest Scoliosis Institute, Dallas, TX, US; 10University of Kansas Medical Center, Kansas City, KS, US; 11Johns Hopkins University, Baltimore, MD, US; 12Duke University, 43. Preoperative regional erector spinae plane blocks Durham, NC, US; 13UVA Health System, Charlottesville, VA, US; reduce opioid use, increase mobilization, and reduce 14Brighton, CO, US length of stay following lumbar spine fusion 1 1 FDA DEVICE/DRUG STATUS: This abstract does not discuss or Robert J. Owen, MD ; Darrel S. Brodke, MD ; Noah Quinlan, 2 1 1 include any applicable devices or drugs. MD ; Brandon D. Lawrence, MD ; W. Ryan Spiker, MD ; Addisyn Poduska, CST3; Nicholas Spina, MD2 39. Critical analysis of anterior/posterior staged vs same 1University Orthopaedic Center, Salt Lake City, US; 2Salt Lake City, day surgery in patients undergoing identical corrective UT, US; 3University of Utah Hospital, Salt Lake City, UT, US surgery for adult spinal deformity FDA DEVICE/DRUG STATUS: This abstract does not discuss or Waleed Ahmad1; Peter G. Passias, MD2; Renaud Lafage, MSc3; include any applicable devices or drugs. Virginie Lafage, PhD3; Breton Line, BS4; Gregory M. Mundis Jr., 5 6 7 MD ; Robert K. Eastlack, MD ; Pierce D. Nunley, MD ; D. Kojo 44. The impact of frailty on patient reported outcome 8 9 10 Hamilton, MD ; Robert A. Hart, MD ; Douglas C. Burton, MD ; measures following elective thoraco-lumbar spine 11 3 Christopher I. Shaffrey, MD ; Frank J. Schwab, MD ; Christopher surgery P. Ames, MD12; Justin S. Smith, MD, PhD13; Shay Bess, MD14; Eric 1 O. Klineberg, MD15; International Spine Study Group16 Philippe Beauchamp-Chalifour, MD, MSc ; Raphaële Charest- Morin, MD2 1New York, NY, US; 2NY Spine Institute, NYU Langone Health, 1 2 New York, NY, US; 3Hospital for Special Surgery, New York, NY, Université Laval, Québec, QC, Canada; Quebec, QC, Canada US; 4Denver International Spine Center, Denver, CO, US; 5Scripps FDA DEVICE/DRUG STATUS: This abstract does not discuss or Clinic Medical Group, Department of Orthopedics, La Jolla, include any applicable devices or drugs. CA, US; 6Scripps Clinic, San Diego, CA, US; 7Spine Institute of Louisiana, Shreveport, LA, US; 8University of Pittsburgh School of Medicine, Pittsburgh, PA, US; 9Swedish Neuroscience Institute, Seattle, WA, US; 10University of Kansas Medical Center, Kansas City, KS, US; 11Duke University, Durham, NC, US; 12University of California, San Francisco, San Francisco, CA, US; 13UVA Health System, Charlottesville, VA, US; 14Denver, CO, US; 15UC, Davis School of Medicine, Sacramento, CA, US; 16Brighton, CO, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. Abstracts 57

45. A prospective, in-depth analysis of perioperative 49. A systematic review of spine surgery complications in anterior thigh symptoms associated with a direct lateral the ambulatorysurgical center setting access approach for lumbar interbody fusion Nadia Hrynewycz, BS1; Thomas Brundage, BS2; Nathaniel Jenkins, Pierce D. Nunley, MD1; Clint P. Hill, MD2; K. Brandon Strenge, MD2; BS, MS3; James Parrish, MPH3; Kern Singh, MD3 3 4 John (Sean) P. Malloy IV, DO, PT, ATC ; Sandeep Kunwar, MD ; 1Chicago, IL, US; 2Midwest Orthopedics at Rush, Chicago, IL, US; 5 Marcus Stone, PhD 3Rush University Medical Center, Chicago, IL, US 1 2 Spine Institute of Louisiana, Shreveport, LA, US; Orthopaedic FDA DEVICE/DRUG STATUS: This abstract does not discuss or 3 Institute of Western KY, Paducah, KY, US; East Coast include any applicable devices or drugs. Orthopaedics, PA, Pompano Beach, FL, US; 4Fremont, CA, US; 5Spine Institute of Louisiana Foundation, Shreveport, LA, US 50. Preoperative depression predicts prolonged opiate FDA DEVICE/DRUG STATUS: Duo Interbody Fusion System usage following lumbar spine fusion (Approved for this indication) Xiao Chen, BA1; Shane Shahrestani, MS2; Alexander Ballatori, BA1; Andy Ton, BS3; Jeffrey C. Wang, MD4; Zorica Buser, PhD5 46. Surgical outcomes in Rett syndrome patients are 1 2 3 comparable to cerebral palsy patients Los Angeles, CA, US; Yorba Linda, CA, US; Anaheim, CA, US; 4USC Spine Center, Los Angeles, CA, US; 5Keck School of 1 2 3 Vishal Sarwahi, MD ; Jesse M. Galina, BS ; Aaron M. Atlas, BS ; Medicine, University of Southern California, Los Angeles, CA, US Chhavi Katyal, MD4; Marina Moguilevitch, MD5; Sayyida S. Hasan, BS3; Yungtai Lo, PhD6; Terry D. Amaral, MD7 FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. 1North Shore LIJ Health System, New Hyde Park, NY, US; 2New Hyde Path, NY, US; 3Cohen Children’s Medical Center, New Hyde Park , NY, US; 4Children’s Hospital at Montefiore Medical Center, 51. Is percutaneous pedicle screws (PPS) fixation Bronx, CT, US; 5Montefiore Medical Center, Bronx, NY, US;6 Albert associated with minimized risk of perioperative proximal Einstein College of Medicine, Bronox, NY, US; 7Northwell Health, junctional kyphosis (PJK) in adult spinal deformity? Lake Success, NY, US Gregory M. Mundis Jr., MD1; Robert K. Eastlack, MD2; Neel FDA DEVICE/DRUG STATUS: This abstract does not discuss or Anand, MD3; Eric O. Klineberg, MD4; Juan S. Uribe, MD5; Han Jo include any applicable devices or drugs. Kim, MD6; Michael Y. Wang, MD7; Pierce D. Nunley, MD8; Adam S. Kanter, MD9; Shay Bess, MD10; Frank J. Schwab, MD6; Paul Park, MD11; Khoi D. Than, MD12; Themistocles S. Protopsaltis, MD13; 47. Does the use of interbodies in lumbar fusions affect Virginie Lafage, PhD6; Renaud Lafage, MSc6; International Spine the reoperation rate for adjacent segment disease Study Group14 (operative ASD)? Data from the Kaiser Permanente 1 National Spine Registry Scripps Clinic Medical Group, Department of Orthopedics, La Jolla, CA, US; 2Scripps Clinic, San Diego, CA, US; 3Cedars- 1 2 Calvin C. Kuo, MD ; Kathryn Royse, PhD, MPH ; Harsimran Sinai Spine Center, Los Angeles, CA, US; 4UC, Davis School of 3 Brara, MD ; Johannes A. Bernbeck, MD; Vartan Tashjian, MD, Medicine, Sacramento, CA, US; 5Barrow Neurological Institute, 4 5 6 MS ; Shayan Rahman, MD ; Kern H. Guppy, MD, PhD ; Jessica E. Phoenix, AZ, US; 6Hospital for Special Surgery, New York, NY, US; 7 1 Harris, MS ; Ravi S. Bains, MD 7University of Miami, Dept of Neurosurgery, Miami, FL, US; 8Spine 1Kaiser Permanente, Oakland, CA, US; 2San Diego, CA, US; Institute of Louisiana, Shreveport, LA, US; 9UPMC-Presbyterian/ 3Southern California Permanente Medical Group, Los Angeles, Dept of Neurological Surgery, Pittsburgh, PA, US; 10Denver, CO, CA, US; 4Kaiser Permanente Medical Center - Fontana, Fontana, US; 11University Of Michigan - Dept of Neurosurgery, Ann Arbor, CA, US; 5Ann Arbor, MI, US; 6Kaiser Permanente Medical Group, MI, US; 12Duke University, Durham, NC, US; 13Department of Sacramento, CA, US; 7Kaiser Permanente, San Diego, CA, US Orthopaedic Surgery, NYU Langone Orthopaedic Hospital, NYU 14 FDA DEVICE/DRUG STATUS: This abstract does not discuss or Langone Health, New York, NY, US; Brighton, CO, US include any applicable devices or drugs. FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. 48. Fusion and decompression vs decompression only for lumbar facet cysts 52. Calcium phosphates with submicron topography enhance human macrophage M2 polarization in vitro Jarren A. Section, MD1; Noorullah Maqsoodi, BS2; Addisu Mesfin, MD3 Lukas A. van Dijk, MSc1; Lizette Utomo, PhD1; Huipin Yuan, PhD2; 3 4 1Strong Memorial Hospital- University of Rochester, Benbrook, Debby Gawlitta, PhD ; Joost DeBruijn, PhD TX, US; 2Rochester, NY, US; 3University of Rochester, Rochester, 1University Medical Centre Utrecht, Utrecht, Netherlands NY, US 2Bilthoven, Netherlands; 3UMC Utrecht, Utrecht, Netherlands; 4 FDA DEVICE/DRUG STATUS: This abstract does not discuss or Kuros Biosciences, Bilthoven, Netherlands include any applicable devices or drugs. FDA DEVICE/DRUG STATUS: MagnetOs Granules (Not approved for this indication), Vitoss Granules (Not approved for this indication) Abstracts 58

53. Biomimetic laser-etched titanium promotes gene 58. Benefits of macroscale topography features on and expression of early bone markers within interbody cages Roland Beard, MS; Margaret R. Van Horn, PhD; Brandon Bucklen, William Walsh, PhD1; Matthew H. Pelletier, PhD2; Tian Wang, PhD PhD3; Daniel Wills, DVM4; Shaeffer Bannigan5; Frank Vizesi, PhD, 6 Globus Medical Audubon, PA, US PhD 1 FDA DEVICE/DRUG STATUS: SINTROS (Globus Medical) Surgical and Orthopaedic Research Labs, Randwick, Maroubra, 2 (Approved for this indication) Australia; Surgcial & Orthopaedic Research Labs, Randwick, NSW, Australia; 3Surgical & Orthopaedic Research Laboratories (SORL) , , Australia; 4Surgical and Orthopaedic Research 54. Titanium plasma spray enhances ability of PEEK to Laboratories, Level 1 Clinical Sci Bldg, Randwick, NSW, Australia; express genes related to bone formation 5San Diego, CA, US; 6SeaSpine, Carlsbad, CA, US Roland Beard, MS; Margaret R. Van Horn, PhD; Brandon Bucklen, FDA DEVICE/DRUG STATUS: Shoreline RT (Approved for this PhD indication) Globus Medical, Audubon, PA, US FDA DEVICE/DRUG STATUS: SUSTAIN (Globus Medical) 59. Does attachment of the dorsolumbar fascia to a (Approved for this indication) spinous process prosthesis affect kinematics at the operative and adjacent levels? An in vitro human cadaveric model 55. Early deformity development following decompressive surgery for lumbar spinal stenosis Daina M. Brooks, BS1; Bryan W. Cunningham, PhD1; Mohit M. 1 2 3 2 Kukreja, MD, MS, DNB ; Kenneth Mullinix, BS ; Nicholas Rolle, BS ; Arya Ahmady, MD; Zachary L. Gordon, MD ; Louis Magdon III, P. Justin Tortolani, MD3 MD1; Nicholas U. Ahn, MD3; Christina W. Cheng, MD4; Christopher 1 2 G. Furey, MD4 Medstar Union Memorial Hospital, Baltimore, MD, US; Audubon, PA, US; 3Baltimore, MD, US 1University Hospitals Cleveland Medical Center, Dept of Orthopaedic Surgery, Cleveland, OH, US; 2Blue Ridge Orthopaedic FDA DEVICE/DRUG STATUS: Crosslink (Approved for this and Spine Center, Warrenton, VA, US; 3University Hospitals indication) Cleveland Medical Center, Cleveland, OH, US; 4Case Western Reserve University, Cleveland, OH, US 60. Beta-lactam antibiotic surgical prophylaxis is safe in FDA DEVICE/DRUG STATUS: This abstract does not discuss or patients with self-reported penicillin allergies: a cohort include any applicable devices or drugs. study of lumbar spine surgery patients Kyle Kesler, MD1; Alan Shamrock, MD2; Christopher Lindsay, MD3; 56. Minimally invasive pedicle screws provide similar Nathan R. Hendrickson, MD, MS4; Joshua M. Eisenberg, MD4; clinical outcomes to open posterior fusion in the Piyush Kalakoti, MD1; Andrew J. Pugely, MD1 management of adult isthmic spondylolisthesis 1University of Iowa, Iowa City, IA, US; 2University of Iowa Hospitals 3 4 Daniel Bowles, MD; Jose A. Canseco, MD, PhD; Christopher and Clinics, Iowa City, IA, US; Iowa City, IA, US; University of Antonacci, MS; Aditya Thandoni, BA; D. Greg Anderson, MD; Mark Iowa, Dept of Orthopedics, Iowa City, IA, US F. Kurd, MD; Alan S. Hilibrand, MD; Christopher K. Kepler, MD, FDA DEVICE/DRUG STATUS: This abstract does not discuss or MBA; Alexander R. Vaccaro, MD, PhD; Gregory D. Schroeder, MD; include any applicable devices or drugs. Joseph K. Lee, MD; Ian D. Kaye, MD Rothman Institute, Thomas Jefferson University, Philadelphia, PA, 61. ALIF vs TLIF for isthmic spondylolisthesis: differences US in radiographic outcomes FDA DEVICE/DRUG STATUS: This abstract does not discuss or Daniel Bowles, MD; Jose A. Canseco, MD, PhD; Christopher include any applicable devices or drugs. Antonacci, MS; Aditya Thandoni, BA; D. Greg Anderson, MD; Mark F. Kurd, MD; Alan S. Hilibrand, MD; Christopher K. Kepler, MD, 57. Congenital scoliosis patients can attain similar curve MBA; Alexander R. Vaccaro, MD, PhD; Gregory D. Schroeder, MD; correction and perioperative outcomes to AIS patients Ian D. Kaye, MD; Joseph K. Lee, MD without the need for hemivertebra excision Rothman Institute, Thomas Jefferson University, Philadelphia, PA, Vishal Sarwahi, MD1; Jesse M. Galina, BS2; Thomas J. Dowling US III, MD3; Jordan Fakhoury, DO4; Sayyida S. Hasan, BS5; Yungtai Lo, FDA DEVICE/DRUG STATUS: This abstract does not discuss or PhD6; Terry D. Amaral, MD7 include any applicable devices or drugs. 1North Shore LIJ Health System, New Hyde Park, NY, US; 2New Hyde Path, NY, US; 3Northwell Health, Plainview Hospital, Plainview, NY, US; 4Northwell, Carle Place, NY, US; 5Cohen Children’s Medical Center, New Hyde Park, NY, US; 6Albert Einstein College of Medicine, Bronox, NY, US; 7Northwell Health, Lake Success, NY, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. Abstracts 59

62. Multimodal analgesic management for lumbar 66. The morbidity, readmissions, and cost for pediatric decompression surgery in the ambulatorysetting clinical cerebral palsy patients undergoing primary spinal fusion case series and review of the literature surgery: a national analysis on 2,779 patients Nathaniel Jenkins, BS, MS1; James Parrish, MPH1; Thomas Nathan J. Lee, MD1; Michael Fields, BS2; Kyle L. McCormick, BA2; Brundage, BS2; Nadia Hrynewycz, BS3; Kern Singh, MD1 Daniel Hong, MD2; Jun S. Kim, MD2; Joseph M. Lombardi, MD3; 4 3 1Rush University Medical Center, Chicago, IL, US; 2Midwest Benjamin D. Roye, MD, MPH ; Lawrence G. Lenke, MD Orthopedics at Rush, Chicago, IL, US; 3Chicago, IL, US 1Columbia University, New York, NY, US; 2New York, NY, US; 3 FDA DEVICE/DRUG STATUS: This abstract does not discuss or Columbia University Department of Orthopaedic Surgery, New 4 include any applicable devices or drugs. York, NY, US; Columbia University Medical Center, New York, NY, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or 63. Three-dimensional printing of titanium without bone include any applicable devices or drugs. graft outperforms PEEK + autologous iliac crest bone graft in sheep interbody fusion model 67. 3D-printed porous biomimetic titanium promotes Jesús Pino Minguez, MD, PhD; Joseph L. Laratta, MD2; Jeffrey L. Gum, MD3; Andrew J. Pugely, MD4; Steven D. Glassman, MD3 osteogenic gene expression in murine mesenchymal stem cells 1Head of HM La Rosaleda Spine Department and Orthopaedic Professor at University of Santiago de Compostela , Department Roland Beard, MS; Margaret R. Van Horn, PhD; Brandon Bucklen, of Surgery, Santiago de Compostela, Coruna, Spain; 2Norton PhD Leatherman Spine, Louisville, KY, US; 3Norton Leatherman Spine Globus Medical, Audubon, PA, US 4 Center, Louisville, KY, US; University of Iowa, Iowa City, IA, US FDA DEVICE/DRUG STATUS: HEDRON (Globus Medical) FDA DEVICE/DRUG STATUS: This abstract does not discuss or (Approved for this indication) include any applicable devices or drugs. 68. Spinal fusion with a resorbable mesh pouch in a 64. Intravenous vs oral acetaminophen administration preclinical posterolateral model in perioperative care of one- and two-level LLIFs with William Walsh, PhD1; Rema Oliver, PhD2; Tian Wang, PhD3; Daniel instrumented posterior lumbar fusion: a comparative Wills, DVM4; Michelle Pacer5; Frank Vizesi, PhD, PhD6 effectiveness study 1Surgical and Orthopaedic Research Labs, Randwick, 1 2 2 Nicole Utah, BS ; Christina Dowe, BS ; Antonio T. Brecevich, MD ; Maroubra, Australia; 2Surgical & Orthopaedic Research Lab- 2 1 5 Fedan Avrumova, BS ; Daniel Alicea, MS ; Frank P. Cammisa, MD ; UNSW, Randwick, Australia; 3Surgical & Orthopaedic Research 2 2 Darren R. Lebl, MD ; Alexander P. Hughes, MD ; Andrew A. Sama, Laboratories (SORL), Sydney, Australia; 4Surgical and Orthopaedic 2 2 2 MD ; Russel C. Huang, MD ; Matthew E. Cunningham, MD, PhD ; Research Laboratories, Level 1 Clinical Sci Bldg, Randwick, NSW, 2 2 Federico P. Girardi, MD ; Celeste Abjornson, PhD ; Chad M. Craig, Australia; 5Oceanside, US; 6SeaSpine, Carlsbad, CA, US MD, FACP1 FDA DEVICE/DRUG STATUS: Resorbable Mesh Bag (Ballast) 1 2 New York, NY, US; Hospital for Special Surgery, New York, NY, (Approved for this indication) US FDA DEVICE/DRUG STATUS: OFIRMEV (Approved for this 69. Ischemic spinal nerve root injury secondary to indication) herniated lumbar intervertebral disc Paul B. Bishop, DC, MD, PhD1; Nicolas Dea, MD, MSc, FRCSC1; 65. Indirect decompression for the treatment of Charles G. Fisher, MD, FRCSC, MHS2 degenerative lumbar stenosis: clinical outcome in a 1 2 consecutive series of 568 patients Blusson Spine Centre, Vancouver, BC, Canada; Vancouver General Hospital, Vancouver, BC, Canada Peter B. Derman, MD, MBA1; Donna D. Ohnmeiss, PhD2; Abbey Lauderback1; Richard D. Guyer, MD1 FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. 1Texas Back Institute, Plano, TX, US; 2Texas Back Institute Research Foundation, Plano, TX, US 70. A biologically-inspired 3D-printed titanium alloy FDA DEVICE/DRUG STATUS: This abstract does not discuss or interbody spacer promotes osseointegration in an ovine include any applicable devices or drugs. lumbar interbody fusion model Margaret R. Van Horn, PhD1; Roland Beard, MS1; Bryan W. Cunningham, PhD2; Kenneth Mullinix, BS3; May Allall1; Brandon Bucklen, PhD1 1Globus Medical, Audubon, PA, US; 2MedStar Union Memorial Hospital, Baltimore, MD, US; 3Audubon, PA, US FDA DEVICE/DRUG STATUS: HEDRON (Globus Medical) (Approved for this indication) Abstracts 60

71. Can the novel lumboiliac triangle technique based 74. Cervical disc arthroplasty for axial neck pain: on biplane oblique fluoroscopy facilitate transforaminal outcomes up to seven years percutaneous endoscopic lumbar discectomy for patients Matthew F. Gornet, MD1; Katrine Sorensen, MSc2; Francine W. with L5-S1 disc herniation combined with high iliac crest? Schranck, RN, BSN3; Anne G. Copay, PhD4 A case-control study of 100 patients 1The Orthopedic Center of St. Louis, St. Louis, MO, US; 1 2 3 Jun-Song Yang, MD ; Peng Liu, MD ; Tuan-Jiang Liu, MD ; Ding- 2Wilmimgton, NC, US; 3SPIRITT Research, Saint Louis, MO, US; 1 Jun Hao, MD 4St. Louis, MO, US 1 Department of Spine Surgery, Honghui Hospital, Xi’an Jiaotong FDA DEVICE/DRUG STATUS: This abstract does not discuss or 2 University, Xi’an, China; Honghui Hospital, Xi’an Jiaotong include any applicable devices or drugs. University, Xi’an, Shaanxi, China; 3Xi’an, China FDA DEVICE/DRUG STATUS: This abstract does not discuss or 75. Prospective, randomized study of lumbar facet include any applicable devices or drugs. replacement and lumbar interbody fusion for spondylolisthesis 72. Accuracy of rod contouring to desired angles with and Michael P. Steinmetz, MD1; Paul M. Arnold, MD2; William C. without a template: implications for achieving desired Welch, MD, FACS, FICS3; Domagoj Coric, MD4; Ahmad N. Nassr, spinal alignment and outcomes MD5 1 2 Justin S. Smith, MD, PhD ; Christopher P. Ames, MD ; Christopher 1Cleveland Clinic, Cleveland, OH, US; 2Carle Foundation Hospital, 3 4 5 R. Good, MD, FACS ; Benny Dahl, MD, PhD ; Paul E. Kraemer, MD ; Urbana, IL, US; 3Penn Neurosurgery, Philadelphia, PA, US; 6 7 Jeffrey L. Gum, MD ; Dennis Devito, MD ; Robert S. Lee, MBBS, 4Carolina Neurosurgery & Spine Associates, Charlotte, NC, US; 8 9 10 FRCS ; Marco Brayda-Bruno, MD ; Christopher Bell, MSc ; Shay 5Professor of Orthopedic Surgery and Neurosurgery, Mayo Clinic 11 Bess, MD College of Medicine and Science Consultant, Department of 1UVA Health System, Charlottesville, VA, US; 2University of Orthopedic Surgery, Rochester, MN, US 3 California, San Francisco, San Francisco, CA, US; Virginia FDA DEVICE/DRUG STATUS: This abstract does not discuss or 4 Spine Institute, Reston, VA, US; Texas Children’s Hospital, include any applicable devices or drugs. Houston, Texas, US; 5Indiana Spine Group, Carmel, IN, US; 6Norton Leatherman Spine Center, Louisville, KY, US; 7Children’s Orthopedics of Atlanta, Atlanta, GA, US; 8Royal National 76. Reduction in opioid medication use after arthroplasty Orthopaedic Hospital NHS Trust, Stanmore, Middlesex, UK; with Prestige LPTM cervical disc as compared to ACDF in 9IRCCS Istituto Ortopedico Galeazzi, Milano, Italy; 10Stryker, patients with two-level surgery: a randomized study with Allendale, NJ, US; 11Denver, CO, US 10-year follow-up FDA DEVICE/DRUG STATUS: This abstract does not discuss or Matthew F. Gornet, MD1; Todd H. Lanman, MD2; J. Kenneth include any applicable devices or drugs. Burkus, MD3; Randall F. Dryer, MD4; Jeffrey R. McConnell, MD5; Scott D. Hodges, DO6; Francine W. Schranck, RN, BSN7; Guorong Ma, PhD8 73. Sex-based difference in response to recombinant 1 2 human bone morphogenetic protein-2 (rhBMP-2) in a rat The Orthopedic Center of St. Louis, St. Louis, MO, US; Beverly 3 posterolateral fusion model Hills, CA, US; The Hughston Clinic, PC, Columbus, GA, US; 4Central Texas Spine Institute, Austin, TX, US; 5LVPG Orthopedics 1 2 Jonathan Paul, MPH, BS ; Mark A. Plantz, BS ; Tejas Nandurkar, and Sports Medicine, Allentown, PA, US; 6Center for Sports 1 2 3 1 MS ; Joseph G. Lyons, BS ; Parker Marsh, BS ; James Foley, MD ; Medicine & Orthopaedics, Chattanooga, TN, US; 7SPIRITT 4 1 5 Allison Wintring, BS ; Eileen Phan, BA ; Elianna Fred ; Soyeon Research, Saint Louis, MO, US; 8Medtronic Spinal and Biologics, 6 6 6 Jeong, MS ; Chawon Yun, PhD ; Silvia Minardi, PhD, MS ; Stuart R. Minneapolis, MN, US Stock, PhD5; Kenneth R. Blank, PhD, MS, MHA7; Robert M. Havey, TM MS8; Muturi Muriuki, PhD9; Avinash G. Patwardhan, PhD10; Erin L. FDA DEVICE/DRUG STATUS: Prestige LP Disc, approved for Hsu, PhD6; Wellington K. Hsu, MD6 2-level cervical disc arthroplasty in 2016 (Approved for this indication) 1Chicago, IL, US; 2Northfield, IL, US;3 Simpson Querrey Institute, Chicago, IL, US; 4University of Louisville School of Medicine, Louisville, KY, US; 5Northwestern University, Feinberg School of 77. The incidence of subsequent lumbar spine surgery Medicine, Chicago, IL, US; 6Northwestern University, Chicago, IL, after lumbar disc arthroplasty: a minimum two-year US; 7Tinley Park, IL, US; 8Edward Hines Jr. VA Hospital, Hines, IL, follow-up 9 10 US; Forest Park, IL, US; Loyola University Medical Center Dept. Dean C. Perfetti, MD, MPH1; Austen Katz, MD2; Alan Job, MD3; of Orthopaedic Surgery, Wheaton, IL, US Jesse M. Galina, BS4; Alexander M. Satin, MD5; Jeff S. Silber, MD, FDA DEVICE/DRUG STATUS: This abstract does not discuss or DC6; David A. Essig, MD7 include any applicable devices or drugs. 1Department of Orthopedic Surgery, Long Island Jewish Medical Center, New Hyde Park, NY, US; 2Long Island Jewish Hospital, Queens, NY, US; 3Northwell Health North Shore-LIJ, New Hyde Park, NY, US; 4New Hyde Path, NY, US; 5American Pain & Wellness, Plano, TX, US; 6Great Neck, NY, US; 7Northwell Health, Great Neck, NY, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. Abstracts 61

78. The current incidence of adjacent segment pathology 81. Seven-year results of a randomized controlled IDE trial following cervical disc arthroplasty (CDA) or anterior for lumbar artificial discs in single level degenerative disc cervical discectomy and fusion (ACDF): a systematic Rolando Garcia Jr., MD, MPH1; Jack E. Zigler, MD2; Kris E. review and meta-analysis of randomized clinical trials Radcliff, MD3; Domagoj Coric, MD4; James J. Yue, MD5; Nicole Chester J. Donnally III, MD1; Parthik Patel, MD1; Jose A. Canseco, Ferko, MSc6; Aaron Situ, MSc, BS7 2 3 4 MD, PhD ; Srikanth Divi, MD; Vadim Goz, MD ; Kartik Shenoy, MD ; 1Orthopedic Care Center, Aventura, FL, US; 2Texas Back Institute, 2 Alan S. Hilibrand, MD Plano, TX, US; 3Rothman Institute, Thomas Jefferson University, 1Philadelphia, PA, US; 2Rothman Institute/Thomas Jefferson Egg Harbor Township, NJ, US; 4Carolina Neurosurgery & Spine University Hospital, Philadelphia, PA, US; 3Rothman Institute, Associates, Charlotte, NC, US; 5CT Ortho Specialists, Hamden, Philadelphia, PA, US; 4Department of Orthopedic Surgery, NYU CT, US; 6Cornerstone Research Group, Burlington, ON, Canada; Langone Orthopedic Hospital, NYU Langone Health, New York, 7Eversana, Burlington, ON, Canada NY, US FDA DEVICE/DRUG STATUS: Activ L (Approved for this FDA DEVICE/DRUG STATUS: This abstract does not discuss or indication), Prods L (Approved for this indication) include any applicable devices or drugs. 82. Interdisciplinary care may reduce delirium in elderly 79. Secondary surgery rate and five-year outcomes of spine patients: the UT Southwestern Perioperative hybrid TDR/ACDF vs multilevel ACDF Optimization of Senior Health Program Glenn R. Buttermann, MD Mark N. Pernik, BA1; Palvasha Deme, BA1; Madelina Nguyen1; 1 1 Midwest Spine Institute LLC, Stillwater, MN, US Salah Aoun, MD ; Owoicho Adogwa, MD, MPH ; Kristen Hall, BS, MBA1; Nickolas A. Stewart1; Luke Dosselman, BS1; Shelley FDA DEVICE/DRUG STATUS: This abstract does not discuss or McDonald, DO, PhD2; Sarah Wingfield, MD3; Carlos A. Bagley, MD, include any applicable devices or drugs. MBA1,4 1UT Southwestern Medical Center, Department of Neurosurgery, 80. FDA trial of decompression and paraspinous tension Dallas, TX, US; 2Duke, Durham, NC, US; 3UT Southwestern Medical band for degenerative spondylolisthesis: 12 months Center, Department of Internal Medicine, Geriatrics Division, follow-up in 93 subjects Dallas, TX, US; 4UT Southwestern Medical Center, Department of Rick C. Sasso, MD1; Ivan Cheng, MD2; William F. Lavelle, MD3; Orthopaedic Surgery, Dallas, TX, US S. Tim Yoon, MD, PhD4; Alan T. Villavicencio, MD5; Kee D. Kim, FDA DEVICE/DRUG STATUS: This abstract does not discuss or MD6; Ravi S. Bains, MD7; Calvin C. Kuo, MD7; Hyun W. Bae, MD8; include any applicable devices or drugs. Elizabeth Yu, MD9; Todd F. Alamin, MD10; Louie C. Fielding11; Jeffrey Fischgrund, MD12; Harel Deutsch, MD13; Khalid A. Sethi, MD, FACS14; Harvinder S. Sandhu, MD15; Michael Stauff, MD16; 83. 2018 Research Grant Award Winner Reginald J. Davis, MD, FACS17; Dennis G. Crandall, MD18; William C. Welch, MD, FACS, FICS19 1Indiana Spine Group, Carmel, IN, US; 2Stanford University, Redwood City, CA, US; 3Upstate Orthopedics, East Syracuse, NY, US; 4The Emory Spine Center, Atlanta, GA, US; 5Boulder Neurosurgical Associates, Boulder, CO, US; 6UC Davis School of Medicine, Sacramento, CA, US; 7Kaiser Permanente, Oakland, CA, US; 8Spine Institute St. John’s Health Center, Los Angeles, CA, US; 9Columbus, OH, US; 10Stanford Medicine Outpatient Center, Redwood City, CA, US; 11Empirical Spine, San Carlos, CA, US; 12Franklin, MI, US; 13Rush University Medical Ctr Dept of Neurosurgery, Chicago, IL, US; 14Southern New York Neurosurgery, Johnson City, NY, US; 15Hospital for Special Surgery, New York, NY, US; 16U Mass Memorial Medical Center, Worcester, MA, US; 17Tampa, FL, US; 18Sonoran Spine Center, Tempe, AZ, US; 19Penn Neurosurgery, Philadelphia, PA, US FDA DEVICE/DRUG STATUS: LimiFlex Paraspinous Tension Band (Investigational/Not approved) Abstracts 62

84. Low density pedicle screw constructs are associated 87. Rates of loosening, failure, and revision of iliac fixation with lower incidence of proximal junctional failure in adult in adult deformity surgery spinal deformity surgery Robert K. Eastlack, MD1; Alexandra Soroceanu, MD, MPH2; Wesley M. Durand1; Han Jo Kim, MD2; D. Kojo Hamilton, MD3; Gregory M. Mundis Jr., MD3; Alan H. Daniels, MD4; Justin S. Renaud Lafage, MSc2; Peter G. Passias, MD4; Themistocles S. Smith, MD, PhD5; Breton Line, BS6; Peter G. Passias, MD7; Pierce Protopsaltis, MD5; Virginie Lafage, PhD2; Justin S. Smith, MD, D. Nunley, MD8; David O. Okonkwo, MD9; Khoi D. Than, MD10; PhD6; Christopher I. Shaffrey, MD7; Munish C. Gupta, MD8; Eric Juan S. Uribe, MD11; Dean Chou, MD12; Khaled M. Kebaish, MD13; O. Klineberg, MD9; Frank J. Schwab, MD2; Jeffrey L. Gum, MD10; Christopher I. Shaffrey, MD14; Shay Bess, MD15; International Gregory M. Mundis Jr., MD11; Robert K. Eastlack, MD12; Khaled Spine Study Group16 13 14 M. Kebaish, MD ; Alexandra Soroceanu, MD, MPH ; Richard 1Scripps Clinic, San Diego, CA, US; 2University of Calgary, 15 16 17 A. Hostin Jr., MD ; Douglas C. Burton, MD ; Shay Bess, MD ; Calgary, Canada; 3Scripps Clinic Medical Group, Department of 18 19 Christopher P. Ames, MD ; Robert A. Hart, MD ; Alan H. Daniels, Orthopedics, La Jolla, CA, US; 4Warren Alpert Medical School 20 21 MD ; International Spine Study Group of BU/RI Hospital, Providence, RI, US; 5UVA Health System, 1Brown University, Alpert Medical School, Providence, RI, US; Charlottesville, VA, US; 6Denver International Spine Center, 2Hospital for Special Surgery, New York, NY, US; 3University of Denver, CO, US; 7NY Spine Institute, NYU Langone Health, Pittsburgh School of Medicine, Pittsburgh, PA, US; 4NY Spine New York, NY, US; 8Spine Institute of Louisiana, Shreveport, Institute, NYU Langone Health, New York, NY, US; 5Department LA, US; 9Pittsburgh, PA, US; 10Duke University, Durham, NC, US; of Orthopaedic Surgery, NYU Langone Orthopaedic Hospital, 11Barrow Neurological Institute, Phoenix, AZ, US; 12University of NYU Langone Health, New York, NY, US; 6UVA Health System, California San Francisco, San Francisco, CA, US; 13Johns Hopkins Charlottesville, VA, US; 7Duke University , Durham, NC, US; University, Baltimore, MD, US; 14Duke University, Durham, NC, US; 8Washington University School of Medicine, St. Louis, MO, US; 15Denver, CO, US; 16Brighton, CO, US 9 10 UC, Davis School of Medicine, Sacramento, CA, US; Norton FDA DEVICE/DRUG STATUS: This abstract does not discuss or 11 Leatherman Spine Center, Louisville, KY, US; Scripps Clinic include any applicable devices or drugs. Medical Group, Department of Orthopedics, La Jolla, CA, US; 12Scripps Clinic, San Diego, CA, US; 13Johns Hopkins University, Baltimore, MD, US; 14University of Calgary, Calgary, Canada; 88. Cell stiffness decreases with severity of disc 15Southwest Scoliosis Institute, Dallas, TX, US; 16University of degeneration and inflammatory stimulation 17 Kansas Medical Center, Kansas City, KS, US; , Denver, CO, US; Nadeen Chahine, PhD1; Eric Leung, BA2; Meghan Cerpa, MPH3; 18 University of California, San Francisco, San Francisco, CA, US; Meghana Vulapalli, BS4; Venkat Boddapati, MD1; Timothy 19 20 Swedish Neuroscience Institute, Seattle, WA, US; Warren Jacobsen, MEng1; Ronald A. Lehman Jr., MD5 Alpert Medical School of BU/RI Hospital, Providence, RI, US; 1 2 21Brighton, CO, US New York, NY, US; The Spine Hospital, New York, NY, US; 3Columbia University Medical Center, New York, NY, US; FDA DEVICE/DRUG STATUS: This abstract does not discuss or 4Columbia University Medical Center, New York, NY, US; 5The include any applicable devices or drugs. Spine Hospital -Columbia University / New York Presbyterian, New York, NY, US 85. Incidence and resolution strategies for early onset FDA DEVICE/DRUG STATUS: This abstract does not discuss or postoperative leg pain following lumbar total disc include any applicable devices or drugs. replacement Richard D. Guyer, MD1; Scott L. Blumenthal, MD1; Donna D. 89. Is academic department teaching status associated Ohnmeiss, PhD1,2; Nicole Ferko, MSc3; Ashley Bonner, PhD4; Aaron with adverse outcomes after lumbar fusion for Situ, MSc, BS4 degenerative spine diseases? 1 Center for Disc Replacement at Texas Back Institute, Plano, TX, Dean C. Perfetti, MD, MPH1; Daniel Kiridly, MD, MBA2; Matthew 2 US; Texas Back Institute Research Foundation, Plano, TX, US; Morris, MD3; Alan Job, MD4; Austen Katz, MD5; Jeff S. Silber, MD, 3 4 Cornerstone Research Group, Burlington, ON, Canada; Eversana, DC6; David A. Essig, MD7 Burlington, ON, Canada 1Department of Orthopedic Surgery, Long Island Jewish Medical FDA DEVICE/DRUG STATUS: activL and ProDisc-L (Approved for Center, New Hyde Park, NY, US; 2Northwell Health Orthopaedic this indication) Surgery, New Hyde Park, NY, US; 3Bronx, NY, US; 4Northwell Health North Shore-LIJ, New Hyde Park, NY, US; 5Long Island 6 7 86. Why are DBMs so variable? Influence of fibers, carrier, Jewish Hospital, Queens, NY, US; Great Neck, NY, US; Northwell and tissue bank Health, Great Neck, NY, US Gregory M. Mundis Jr., MD1; Nick Russell, PhD2; William Walsh, FDA DEVICE/DRUG STATUS: This abstract does not discuss or PhD3; Peter Kim, MS4; Jennifer Chen, PhD5; Frank Vizesi, PhD, include any applicable devices or drugs. PhD5 1Scripps Clinic Medical Group, Department of Orthopedics, La Jolla, CA, US; 2Carlsbad, CA, US; 3Surgical and Orthopaedic Research Labs, Randwick, Maroubra, Australia; 4SeaSpine Orthopedics, Carlsbad, CA, US; 5SeaSpine, Carlsbad, CA, US FDA DEVICE/DRUG STATUS: Grafton (Approved for this indication), DBX Putty (Approved for this indication), Optium Putty (Approved for this indication) Abstracts 63

90. Nanoroughened microstructured orthopaedic implant 94. What is the difference in patient outcomes in surfaces induce osteogenesis via soluble signaling circumferential minimally invasive (cMIS) vs open factors produced by MSCs correction of adult scoliosis? Michael Berger, BS1; David Joshua Cohen, MD2; Kyla Bosh2; Dean Chou, MD1; Peter G. Passias, MD2; Gregory M. Mundis Jr., Michelle B. Gallagher, MS3; Paul J. Slosar, MD4; Zvi S. Schwartz; MD3; Renaud Lafage, MSc4; Robert K. Eastlack, MD5; Kai-Ming G. Barbara D. Boyan, PhD5 Fu, MD, PhD6; Richard G. Fessler, MD, PhD7; Paul Park, MD8; Khoi 9 10 11 1VCU College of Engineering, Department of Biomedical D. Than, MD ; Neel Anand, MD ; Juan S. Uribe, MD ; Adam S. 12 13 14 Engineering, Richmond, VA, US; 2Virginia Commonwealth Kanter, MD ; Shay Bess, MD ; Eric O. Klineberg, MD ; Han Jo 4 15 16 University, Richmond, VA, US; 3Medtronic (Titan Spine), Mequon, Kim, MD ; Richard A. Hostin Jr., MD ; Khaled M. Kebaish, MD ; 17 4 WI, US; 4SpineCare Medical Group, Daly City, CA, US; 5Richmond, Munish C. Gupta, MD ; Virginie Lafage, PhD ; International Spine 18 VA, US Study Group 1 FDA DEVICE/DRUG STATUS: Interbody Fusion Implants University of California San Francisco, San Francisco, CA, US; 2 (Approved for this indication) NY Spine Institute, NYU Langone Health, New York, NY, US; 3Scripps Clinic Medical Group, Department of Orthopedics, La Jolla, CA, US; 4Hospital for Special Surgery, New York, NY, 91. Long term follow-up of adolescent idiopathic scoliosis US; 5Scripps Clinic, San Diego, CA, US; 6Weill Cornell Medicine/ patients who had pedicle screw and fusion to the lower NewYork Presbyterian, New York, NY, US; 7Rush University lumbar vertebrae: low back pain study Medical Center, Dept of Neuro Surgery, Chicago, IL, US; 8 Xie En, MD University Of Michigan - Dept of Neurosurgery, Ann Arbor, MI, US; 9Duke University, Durham, NC, US; 10Cedars-Sinai Spine Hong Hui Hospital, Xi’an Jiaotong University College of Medicine, Center, Los Angeles, CA, US; 11Barrow Neurological Institute, Xi’an, Shan Xi, China Phoenix, AZ, US; 12UPMC-Presbyterian/Dept of Neurological FDA DEVICE/DRUG STATUS: This abstract does not discuss or Surgery, Pittsburgh, PA, US; 13Denver, CO, US; 14UC, Davis School include any applicable devices or drugs. of Medicine, Sacramento, CA, US; 15Southwest Scoliosis Institute, Dallas, TX, US; 16Johns Hopkins University, Baltimore, MD, US; 17Washington University School of Medicine, St. Louis, MO, US; 92. Opioid use after anterior cervical spine surgery: what 18 is the appropriate prescription quantity? Brighton, CO, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or Francis C. Lovecchio, MD1; Ajay Premkumar, MD2; Michael E. include any applicable devices or drugs. Steinhaus, MD1; Dianna L. Mejia, BA2; Alexander Koo2; Virginie Lafage, PhD1; Sravisht Iyer, MD1; Russel C. Huang, MD1; Darren R. Lebl, MD1; Sheeraz A. Qureshi, MD, MBA1; Han Jo Kim, MD1; Kern 95. PROMIS scores alone are not a reliable measure of Singh, MD3; Todd J. Albert, MD1 patient outcomes after surgery for lumbar stenosis 1Hospital for Special Surgery, New York, NY, US; 2New York, NY, Andrew Y. Liu, MD1; Aron Sulovari, BA2; Noorullah Maqsoodi, BS3; US; 3Rush University Medical Center, Chicago, IL, US Clifford R. Everett, MD, MPH4; Addisu Mesfin, MD4 FDA DEVICE/DRUG STATUS: This abstract does not discuss or 1URMC Orthopedics, Rochester, NY, US; 2University of Rochester include any applicable devices or drugs. School of Medicine and Dentistry, Rochester, NY, US; 3Rochester, NY, US; 4University of Rochester, Rochester, NY, US 93. Cost utility analysis of a combined approach for FDA DEVICE/DRUG STATUS: This abstract does not discuss or surgical correction of adult spinal deformity include any applicable devices or drugs. Waleed Ahmad1; Peter G. Passias, MD2; Virginie Lafage, PhD3; Renaud Lafage, MSc3; Khaled M. Kebaish, MD4; Michael P. Kelly, 96. Assessing the predictive ability of metabolic MD; Jeffrey L. Gum, MD5; Breton Line, BS6; Robert A. Hart, MD7; syndrome-ATP III for survival and complications in Douglas C. Burton, MD8; Justin S. Smith, MD, PhD9; Christopher P. patients with metastatic spinal cord compression Ames, MD10; Christopher I. Shaffrey, MD11; Frank J. Schwab, MD3; Nida Fatima, MD, MBBS; Elie Massaad, MD; Muhamed Richard A. Hostin Jr., MD12; Shay Bess, MD13; International Spine 14 Hadzipasic, MD, PhD; Ganesh M. Shankar, MD, PhD; John H. Shin, Study Group MD 1New York, NY, US; 2NY Spine Institute, NYU Langone Health, 3 Department of Neurosurgery, Massachusetts General Hospital, New York, NY, US; Hospital for Special Surgery, New York, Harvard Medical School, Boston, MA, US NY, US; 4Johns Hopkins University, Baltimore, MD, US; 5Norton Leatherman Spine Center, Louisville, KY, US; 6Denver International FDA DEVICE/DRUG STATUS: This abstract does not discuss or Spine Center, Denver, CO, US; 7Swedish Neuroscience Institute, include any applicable devices or drugs. Seattle, WA, US; 8University of Kansas Medical Center, Kansas City, KS, US; 9UVA Health System, Charlottesville, VA, US; 10University of California, San Francisco, San Francisco, CA, US; 11Duke University, Durham, NC, US; 12Southwest Scoliosis Institute, Dallas, TX, US; 13Denver, CO, US; 14Brighton, CO, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. Abstracts 64

97. Complications following adult spinal deformity impact 101. Prospective evaluation of degenerative cervical length of stay and are driven by intervention severity and myelopathy in asymptomatic patients over 60 years can be predicted using a weighted score Ryan M. Schiedo, MD1; Ankur Narain, MD1; Samuel Adams, MD2; Eric O. Klineberg, MD1; Renaud Lafage, MSc2; Virginie Lafage, Sara Holmes, MS2; Letterio Politi, MD1; Patrick J. Connolly, MD1; PhD2; Justin S. Smith, MD, PhD3; Christopher I. Shaffrey, MD4; Michael Stauff, MD1 5 2 Gregory M. Mundis Jr. , MD ; Han Jo Kim, MD ; Munish C. 1University of Massachusetts Memorial Medical Center, 6 7 8 Gupta, MD ; Christopher P. Ames, MD ; Peter G. Passias, MD ; Worcester, MA, US; 2University of Massachusetts Medical School, 9 10 Themistocles S. Protopsaltis, MD ; Douglas C. Burton, MD ; Worcester, MA, US Frank J. Schwab, MD2; Shay Bess, MD11; International Spine Study Group12 FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. 1UC, Davis School of Medicine, Sacramento, CA, US; 2Hospital for Special Surgery, New York, NY, US; 3UVA Health System, Charlottesville, VA, US; 4Duke University, Durham, NC, US; 5Scripps 102. The gait deviation index as an indicator of gait Clinic Medical Group, Department of Orthopedics, La Jolla, CA, abnormality amongdegenerative spinal pathologies 6 US; Washington University School of Medicine, St. Louis, MO, Damon E. Mar, PhD1; Isador H. Lieberman, MD, FRCSC, MBA2; 7 US; University of California, San Francisco, San Francisco, CA, Ram Haddas, PhD, MSc, MEng1 8 US; NY Spine Institute, NYU Langone Health, New York, NY, US; 1 2 9Department of Orthopaedic Surgery, NYU Langone Orthopaedic Texas Back Institute, Plano, TX, US; Scoliosis and Spine Tumor Hospital, NYU Langone Health, New York, NY, US; 10University of Center, Texas Back Institute, Texas Health Presbyterian Hospital Kansas Medical Center, Kansas City, KS, US; 11Denver, CO, US; Plano, Plano, TX, US 12Brighton, CO, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. include any applicable devices or drugs. 103. Discharge to subacute rehabilitation is a predictor of 98. Rapid recovery pathway utilizing intrathecal morphine wound complications after spine surgery decreases overall hospital costs and improves quality of Daniel Bowles, MD1; Jose A. Canseco, MD, PhD1; Nicholas care in adolescent idiopathic scoliosis Semenza, BS2; Ariana Reyes, MD3; Parthik Patel, MD2; Fortunato 3 1 1 1 2 3 Padua, MD, MSc ; D. Greg Anderson, MD ; Mark F. Kurd, MD ; Alan Vishal Sarwahi, MD ; Sayyida S. Hasan, BS ; Benita Liao, MD ; 1 1 4 5 6 S. Hilibrand, MD ; Christopher K. Kepler, MD, MBA ; Alexander R. Jesse M. Galina, BS ; Terry D. Amaral, MD ; Yungtai Lo, PhD ; 1 1 Aaron M. Atlas, BS2; Michelle Kars, MD3 Vaccaro, MD, PhD ; Gregory D. Schroeder, MD 1 1 2 Rothman Insgitute, Thomas Jefferson University, Philadelphia, North Shore LIJ Health System, New Hyde Park, NY, US; Cohen 2 3 Children’s Medical Center, New Hyde Park, NY, US; 3Northwell PA, US; Philadelphia, PA, US; Rothman Orthopaedic Institute, Health, New Hyde Park, NY, US; 4New Hyde Path, NY, US; Philadelphia, GA, US 5Northwell Health, Lake Success, NY, US; 6Albert Einstein College FDA DEVICE/DRUG STATUS: This abstract does not discuss or of Medicine, Bronox, NY, US include any applicable devices or drugs. FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. 104. At-risk tackling techniques in American football Rex A. Marco, MD; Rachel Bratescu, MD 99. Radiographic assessment of fusion: a comparison Houston Methodist Orthopedics & Sports Medicine, Houston, TX, of interbody spacers, following anterior cervical US decompression and fusion FDA DEVICE/DRUG STATUS: This abstract does not discuss or 1 2 Tianna Bennett, BS ; Karen Weissmann, MD ; Renaud Lafage, include any applicable devices or drugs. MSc3; Jonathan Elysee3; Basel Sheikh Alshabab, MD3; Virginie Lafage, PhD3; Russel C. Huang, MD3; Han Jo Kim, MD3; Darren R. Lebl, MD3; Todd J. Albert, MD3 105. ALIF generates better correction of the fractional

1 2 lumbar curve vs posterior instrumentation alone in spinal New York, NY, US; Fundacion medica san cristobal, Santiago, deformity fusion to the pelvis Region metropolitana, Chile; 3Hospital for Special Surgery, New York, NY, US Benjamin J. Geddes, MD1; Steven D. Glassman, MD1; Tino Mkorombindo, BS2; Jonathan Gardner2; Leah Y. Carreon, MD, FDA DEVICE/DRUG STATUS: This abstract does not discuss or MSc1 include any applicable devices or drugs. 1Norton Leatherman Spine Center, Louisville, KY, US; 2Louisville, KY, US 100. Participation in bundled payments in spine surgery was associated with lower readmission rates: the one- FDA DEVICE/DRUG STATUS: This abstract does not discuss or year BPCI-Advanced experience include any applicable devices or drugs. Natalie Glass, PhD1; Ashley Bell, BS2; Andrew J. Pugely, MD2 1University of Iowa Hospitals & Clinics, Iowa City, IA, US; IA, US; 2University of Iowa, Iowa City, IA, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. Abstracts 65

106. Predictive probability of the global alignment and 109. Radiographic predictors of indirect neural proportion score for the development of mechanical decompression in minimally invasive transpsoas lateral failure following adult spinal deformity surgery in Asian interbody fusion patients Corey Walker, MD1; Jakub Godzik, MD2; Jay D. Turner, MD, PhD3; Mitsuru Yagi, MD, PhD1; Satoshi Suzuki, MD2; Naobumi Juan S. Uribe, MD1 3 4 Hosogane, MD, PhD ; Ejiiro Okada, MD ; Osahiko Tsuji, MD, 1Barrow Neurological Institute, Phoenix, AZ, US; 2Phoenix, AZ, US; 5 6 7 PhD ; Narihito Nagoshi, MD, PhD ; Nobuyuki Fujita, MD ; Masaya 3Barrow Brain and Spine, Phoenix, AZ, US Nakamura, MD, PhD1; Morio Matsumoto, MD8; Kota Watanabe, MD9 FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. 1Department of Orthopedic Surgery, Keio University School of Medicine, Tokyo, Japan; 2Keio University, Tokyo, Japan; 3Kyorin University, Mitaka, Tokyo, Japan; 4Saiseikai Central Hospital, 110. Clinical significance of lateral pedicle screw Tokyo, Japan; 5Saitama, Japan; 6Toronto Western Hospital, malposition in the lumbar spine 7 8 Toronto, ON, Canada; Fujita Health Univ., Aichi, Japan; Keio Isabel C. Smith, BS1; Samuel W. Golenbock, MSc1; Raymond 9 University School of Medicine, Tokyo, Japan; Keio University, Hwang, MD, MS, MBA2; Gyu Ho Lee, MA3; Jeffrey Fischgrund, Keio, Japan MD4; Kevin Baker, PhD5; Daniel K. Park, MD6; Paul M. Arnold, MD7; FDA DEVICE/DRUG STATUS: This abstract does not discuss or Rick C. Sasso, MD8; David H. Kim, MD9 include any applicable devices or drugs. 1New England Baptist Hospital, Boston, MA, US; 2New England Baptist Hospital, New England Orthopedic and Spine Surgery, 3 107. Effect of osteoporosis and bisphosphonate on Chestnut Hill, MA, US; Icahn School of Medicine at Mount Sinai, 4 5 reoperations in adult spinal deformity New York, NY, US; Franklin, MI, US; Beaumont Health, Royal Oak, MI, US; 6Southfield, MI, US;7 Carle Foundation Hospital, Urbana, 1 2 3 Waleed Ahmad ; Joshua Bell, MD ; Katherine E. Pierce, BS ; Sara IL, US; 8Indiana Spine Group, Carmel, IN, US; 9Tufts University 4 5 6 Naessig, BS ; Frank A. Segreto, BS ; Shaleen N. Vira, MD ; Virginie Medical Group, NEBH, Boston, MA, US Lafage, PhD7; Carl B. Paulino, MD8; Andrew J. Schoenfeld, MD9; Bassel G. Diebo, MD10; Hamid Hassanzadeh, MD11; Peter G. FDA DEVICE/DRUG STATUS: This abstract does not discuss or Passias, MD12 include any applicable devices or drugs. 1New York, NY, US; 2University of Virginia, Department of Orthopaedics, Charlottesville, VA, US; 3NYU Spine Research Lab, 111. Drivers of cost in primary single-level lumbar fusion New York, NY, US; 4NYU Langone Hospital, New York NY, US; surgery 5 NYU Langone Medical Center - Orthopaedic Hospital, Manhattan, Raymond Hwang, MD, MS, MBA1; Samuel W. Golenbock, MSc2; 6 NY, US; Department of Orthopaedic Surgery, UT Southwestern David H. Kim, MD3 7 Medical Center, Dallas, TX, US; Hospital for Special Surgery, 1 8 New England Baptist Hospital, New England Orthopedic and New York, NY, US; SUNY Downstate Medical Center, Brooklyn, 2 9 Spine Surgery, Chestnut Hill, MA, US; New England Baptist NY, US; Brigham and Women’s Hospital, Boston, MA, US; 3 10Department of Orthopaedic Surgery, SUNY Downstate Medical Hospital, Boston, MA, US; Tufts University Medical Group, NEBH, Center, Brooklyn, NY, US; 11University of Virginia, Department of Boston, MA, US Orthopedic Surgery, Charlottesville, VA, US; 12NY Spine Institute, FDA DEVICE/DRUG STATUS: This abstract does not discuss or NYU Langone Health, New York, NY, US include any applicable devices or drugs. FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. 112. Degenerative disc disease and isthmic spondylolisthesis have similar outcomes after L5-S1 ALIF 108. A novel bone graft has higher fusion rate than local Bryce Basques, MD, MHS1; Garrett Harada, MD2; Sapan D. autologous bone in stand-alone posterolateral fusion: a Gandhi, MD3; Samuel Rudisill, BS4; Zakariah Siyaji, BS4; Omar propensity score adjusted analysis Alam, MD3; Frank M. Phillips, MD4 Scott D. Daffner, MD1; Joshua Bunch, MD2; Howard S. An, MD3; 1Thomas Jefferson University, Philadelphia, PA, US; 2Los Angeles, Douglas C. Burton, MD2; Robert. Milam IV, MD4; Daniel K. Park, CA, US; 3Rush University Medical Center, Chicago, IL, US; MD5; Peter G. Whang, MD, FACS6; K. Brandon Strenge, MD7; John 4Midwest Orthopedics at Rush, Chicago, IL, US 8 Jones, MA, MS FDA DEVICE/DRUG STATUS: This abstract does not discuss or 1West Virginia University School of Medicine, Morgantown, WV, include any applicable devices or drugs. US; 2University of Kansas Medical Center, Kansas City, KS, US; 3Rush University Medical Center, Department of Orthopedic 4 113. Lumbar discectomy patients who undergo Surgery, Chicago, IL, US; OrthoCarolina Spine Center, Charlotte, reoperation experience worse clinical outcomes and NC, US; 5Southfield, MI, US;6 Yale University - School of Medicine, 7 greater socioeconomic burden four years after the New Haven, CT, US; The Orthopaedic Institute of Western primary procedure Kentucky, Paducah, KY, US; 8Bioventus LLC, Durham, NC, US Peter D. Klassen, MD1; Richard Bostelmann, MD2; Claudius FDA DEVICE/DRUG STATUS: This abstract does not discuss or Thome, MD, PhD3 include any applicable devices or drugs. 1Hospital Lingen, Lingen, Germany; 2Duesseldorf, Germany; 3Medical University Innsbruck, Innsbruck, Austria FDA DEVICE/DRUG STATUS: Barricaid Annular Closure Device (ACD) - p.m.A-approved (Approved for this indication) Abstracts 66

114. Dual thread screw design provides equivalent fixation 118. The incremental clinical benefit of adding layers of to upsized screw diameter in revision pedicle screw complexity to the planning and execution of adult spinal instrumentation deformity corrective surgery Joseph L. Laratta, MD1; Ryan Weegens, BA2; Jeffrey L. Gum, Peter G. Passias, MD1; Katherine E. Pierce, BS2; Virginie Lafage, MD1; Michael J. Voor, PhD3; Leah Y. Carreon, MD, MSc1; Steven D. PhD3; Renaud Lafage, MSc3; Gregory M. Mundis Jr., MD4; Jeffrey Glassman, MD1 L. Gum, MD5; Khaled M. Kebaish, MD6; Robert K. Eastlack, MD7; 8 9 1Norton Leatherman Spine, Center, Louisville, KY, US; 2University Bassel G. Diebo, MD ; Justin S. Smith, MD, PhD ; Christopher P. 10 11 of Louisville School of Medicine, Louisville, KY, US; 3University of Ames, MD ; Christopher I. Shaffrey, MD ; Douglas C. Burton, 12 13 14 Louisville, Louisville, KY, US MD ; Robert A. Hart, MD ; Shay Bess, MD ; Frank J. Schwab, MD3; Munish C. Gupta, MD15; International Spine Study Group16 FDA DEVICE/DRUG STATUS: This abstract does not discuss or 1 include any applicable devices or drugs. NY Spine Institute, NYU Langone Health, New York, NY, US; 2NYU Spine Research Lab, New York, NY, US; 3Hospital for Special Surgery, New York, NY, US; 4Scripps Clinic Medical 115. Preoperative factors associated with outpatient Group, Department of Orthopedics, La Jolla, CA, US; 5Norton lumbar decompression surgery Leatherman Spine Center, Louisville, KY, US; 6Johns Hopkins 7 Ariana Reyes, MD1; Jose A. Canseco, MD, PhD2; Daniel Bowles, University, Baltimore, MD, US; Scripps Clinic, San Diego, CA, US; 8 MD3; Parthik Patel, MD4; Michael Chang, BA4; Mark F. Kurd, MD5; Department of Orthopaedic Surgery, SUNY Downstate Medical 9 D. Greg Anderson, MD6; Alan S. Hilibrand, MD6; Christopher K. Center, Brooklyn, NY, US; UVA Health System, Charlottesville, 10 Kepler, MD, MBA6; Alexander R. Vaccaro, MD, PhD6; Gregory D. VA, US; University of California, San Francisco, San Francisco, 11 12 Schroeder, MD2 CA, US; Duke University, Durham, NC, US; University of Kansas 13 1 2 Medical Center, Kansas City, KS, US; Swedish Neuroscience Rothman Orthopaedic Institute, Philadelphia, GA, US; Rothman Institute, Seattle, WA, US; 14Denver, CO, US; 15Washington Institute/Thomas Jefferson University Hospital, Philadelphia, PA, 16 3 4 University School of Medicine, St. Louis, MO, US; Brighton, CO, US; Rothman Orthopaedics, Philadelphia, PA, US; Philadelphia, US PA, US; 5Rothman Institute, Bryn Mawr, PA, US; 6Rothman Institute, Philadelphia, PA, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. 119. Even acute preoperative opioid use before adult spinal deformity surgery associated with increased 116. Decompression of far-out syndrome using unilateral reoperations at five years biportal endoscopy: surgical techniques and clinical outcome Andre Samuel, MD1; Francis C. Lovecchio, MD1; Ajay Premkumar, MD2; Avani S. Vaishnav, MBBS; Han Jo Kim, MD1; Steven J. Man Kyu Park, MD McAnany, MD3; Sravisht Iyer, MD1; Todd J. Albert, MD1; Catherine Parkweonwook hospital, Busan, South Korea Himo Gang, MPH1; Sheeraz A. Qureshi, MD, MBA1 FDA DEVICE/DRUG STATUS: This abstract does not discuss or 1Hospital for Special Surgery, New York, NY, US; 2New York, NY, include any applicable devices or drugs. US; 3Hospital for Special Surgery, Stamford, CT, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or 117. Zero PCA is an achievable target for postoperative include any applicable devices or drugs. rapid recovery management of AIS patients Vishal Sarwahi, MD1; Sayyida S. Hasan, BS2; Michelle Kars, MD3; 120. An enhanced risk-adjustment method for defining Benita Liao, MD3; Jesse M. Galina, BS4; Yungtai Lo, PhD5; Terry D. bundled payments in complex spine surgery: an analysis Amaral, MD6 of Medicare beneficiaries 1North Shore LIJ Health System, New Hyde Park, NY, US; 2Cohen Azeem T. Malik, MBBS1; Jeffery Kim, MD1; Elizabeth Yu, MD2; Children’s Medical Center, New Hyde Park, NY, US; 3Northwell Safdar N. Khan, MD1 4 5 Health, New Hyde Park, NY, US; New Hyde Path, NY, US; Albert 1 6 The Ohio State University Wexner Medical Center, Columbus, Einstein College of Medicine, Bronox, NY, US; Northwell Health, OH, US; 2Columbus, OH, US Lake Success, NY, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. include any applicable devices or drugs.

121. Effects of long-term opioid vs long-term NSAID use prior to lumbar spinal fusion Alexander Ballatori, BA1; Shane Shahrestani, MS2; Andy Ton, BS3; Xiao Chen, BA1; Zorica Buser, PhD4; Jeffrey C. Wang, MD5 1Los Angeles, CA, US; 2Yorba Linda, CA, US; 3Anaheim, CA, US; 4Keck School of Medicine, University of Southern California, Los Angeles, CA, US; 5USC Spine Center, Los Angeles, CA, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. Abstracts 67

122. Variation in 90-day neurological complications 126. Enhanced utility with greater number of levels across increasing fusion levels for posterior cervical treated for patient-specific, pre-contoured rods in fusion: a five-year analysis posterior cervical fusion Neil V. Shah, MD, MS1; Ishaan Jain, BS2; George A. Beyer, MS3; Cole Bortz, BA1; Katherine E. Pierce, BS2; Haddy Alas, BS3; Avery Peter G. Passias, MD4; Nicolas Lonjon, PhD5; Nicholas H. Post, Brown, BS3; Shaleen N. Vira, MD4; Bassel G. Diebo, MD5; Peter G. MD6; Carl B. Paulino, MD3; Vincent Challier, MD7; Bassel G. Diebo, Passias, MD6 1 MD 1New York, NY, US; 2NYU Spine Research Lab, New York, NY, US; 1Department of Orthopaedic Surgery, SUNY Downstate Medical 3Department of Orthopedic Surgery, NYU Langone Orthopedic Center, Brooklyn, NY, US; 2Brooklyn, NY, US; 3SUNY Downstate Hospital, NYU Langone Health, New York, US; 4Department of Medical Center, Brooklyn, NY, US; 4NY Spine Institute, NYU Orthopaedic Surgery, UT Southwestern Medical Center, Dallas, Langone Health, New York, NY, US; 5CHU Gui d Chauliac, TX, US; 5Department of Orthopaedic Surgery, SUNY Downstate Montpellier, France; 6SUNY Downstate, Brooklyn, NY, US; 7Spine Medical Center, Brooklyn, NY, US; 6NY Spine Institute, NYU Unit, Clinique Francheville, Perigueux, France Langone Health, New York, NY, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. include any applicable devices or drugs.

123. Residual foraminal stenosis and increasing levels 127. Preoperative optimization of modifiable frailty decompressed are risk factors for postoperative C5 palsy factors reduces risk of hospital acquired conditions in Robert Brenner, MD, MSc1; Carolyn Stickley, BS2; Eaman Balouch, elective surgical spine patients MD, PhD3; Nicholas O’Malley, BS4; Jack Zhong, BA5; Carlos Leon, Katherine E. Pierce, BS1; Sara Naessig, BS2; Waleed Ahmad3; BS6; Constance Maglaras, PhD3; Ethan W. Ayres, MPH1; Yong H. Frank A. Segreto, BS4; Shaleen N. Vira, MD5; Constance Maglaras, Kim, MD1; Aaron J. Buckland, MBBS, FRACS1 PhD3; Brooke K. O’Connell, MS3; Carl B. Paulino, MD6; Joshua Bell, 7 8 9 1Department of Orthopedic Surgery, NYU Langone Orthopedic MD ; Hamid Hassanzadeh, MD ; Renaud Lafage, MSc ; Virginie 9 3 Hospital, NYU Langone Health US; 2Department of Orthopedic Lafage, PhD ; Tina Raman, MD ; Themistocles S. Protopsaltis, 10 10 11 Surgery, NYU Langone Health, New York, NY, US; 3New York, NY, MD ; Aaron J. Buckland, MBBS, FRACS ; Bassel G. Diebo, MD ; 12 US; 4NYU Langone Dept. of Orthopedic Surgery, Division of Spine, Peter G. Passias, MD New York, NY, US; 5NYU langone Spine Research Center, New York, 1NYU Spine Research Lab, New York, NY, US; 2NYU Langone NY, US; 6NYU Langone Medical Center, , NY, US Hospital, New York NY, US; 3New York, NY, US; 4NYU Langone FDA DEVICE/DRUG STATUS: This abstract does not discuss or Medical Center - Orthopaedic Hospital, Manhattan, NY, US; 5 include any applicable devices or drugs. Department of Orthopaedic Surgery, UT Southwestern Medical Center, Dallas, TX, US; 6SUNY Downstate Medical Center, Brooklyn, NY, US; 7University of Virginia, Department 124. Enhanced recovery after surgery protocols in spine of Orthopaedics, Charlottesville, VA, US; 8University of Virginia, surgery: harnessing national data to identify optimal Department of Orthopedic Surgery, Charlottesville, VA, US; protocols 9Hospital for Special Surgery, New York, NY, US; 10Department of Murray Echt, MD1; Jashvant Poeran, MD, PhD2; Nicole Orthopaedic Surgery, NYU Langone Orthopaedic Hospital, NYU 11 Zubizarreta, MPH3; Stavros G. Memtsoudis, MD, PhD4; Saad B. Langone Health, New York, NY, US; Department of Orthopaedic 12 Chaudhary, MD, MBA5 Surgery, SUNY Downstate Medical Center, Brooklyn, NY, US; NY Spine Institute, NYU Langone Health, New York, NY, US 1Bronx, NY, US; 2New York, NY, US; 3Icahn School of Medicine at Mount Sinai, New York, NY, US; 4Hospital for Special Surgery, FDA DEVICE/DRUG STATUS: This abstract does not discuss or New York, NY, US; 5Mount Sinai Health System, New York, NY, US include any applicable devices or drugs. FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. 128. Subacute and chronic preoperative opioid use associated with reoperations in single-level ACDF patients without myelopathy 125. High volume surgeons have better surgical outcomes and lower costs Andre Samuel, MD1; Francis C. Lovecchio, MD1; Ajay Premkumar, 2 3 1 2 MD ; Avani S. Vaishnav, MBBS; Steven J. McAnany, MD ; Sravisht Vishal Sarwahi, MD ; Jesse M. Galina, BS ; Sayyida S. Hasan, 1 1 1 3 3 4 Iyer, MD ; Han Jo Kim, MD ; Todd J. Albert, MD ; Catherine Himo BS ; Aaron M. Atlas, BS ; Thomas J. Dowling III, MD ; Jordan Gang, MPH1; Sheeraz A. Qureshi, MD, MBA1 Fakhoury, DO5; Yungtai Lo, PhD6; Terry D. Amaral, MD7 1 2 1 2 Hospital for Special Surgery, New York, NY, US; New York, NY, North Shore LIJ Health System, New Hyde Park, NY, US; New US; 3Hospital for Special Surgery, Stamford, CT, US Hyde Path, NY, US; 3Cohen Children’s Medical Center, New Hyde Park, NY, US; 4Northwell Health, Plainview Hospital, Plainview, NY, FDA DEVICE/DRUG STATUS: This abstract does not discuss or US; 5Northwell, Carle Place, NY, US; 6Albert Einstein College of include any applicable devices or drugs. Medicine, Bronox, NY, US; 7Northwell Health, Lake Success, NY, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. Abstracts 68

129. GAP score with modified relative pelvic version (RPV) 133. Cost effectiveness of adult lumbar scoliosis surgery: parameter: GAP-V score an as-treated analysis from the adult symptomatic scoliosis surgery trial with five-year follow-up Jeffrey Kim, MD; Woojin Cho, MD, PhD; Adam D. Nessim, BS; Ariella Applebaum, BA Steven D. Glassman, MD1; Leah Y. Carreon, MD, MSc1; 2 Bronx, NY, US Christopher I. Shaffrey, MD ; Michael P. Kelly, MD; Charles H. Crawford III, MD1; Elizabeth Yanik, PhD, MSc3; Jon D. Lurie, MD, FDA DEVICE/DRUG STATUS: This abstract does not discuss or MS4; Shay Bess, MD5; Christine R. Baldus, RN6; Keith H. Bridwell, include any applicable devices or drugs. MD7 1Norton Leatherman Spine Center, Louisville, KY, US; 2Duke 130. Hounsfield units (HU) on computed tomography University, Durham, NC, US; 3Washington University in St. Louis, (CT) correlates with cage subsidence after lateral lumbar St. Louis, MO, US; 4Dartmouth College, Lebanon, NH, US; 5Denver, interbody fusion (LLIF) CO, US; 6Washington University, Department of Orthopedics, 7 Zhuo Xi, MD, PhD1; Huibing Ruan, MD2; Shane Burch, MD3; Vedat St. Louis, MO, US; Washington University In St. Louis School of Deviren, MD3; Sigurd H. Berven, MD4; Dean Chou, MD3 Medicine, Saint Louis, MO, US 1Neurosurgery Department Shengjing Hospital of China Medical FDA DEVICE/DRUG STATUS: This abstract does not discuss or University, Liaoning, Shenyang, China; 2The Fourth Affiliated include any applicable devices or drugs. Hospital of Nanchang University, Jiangxi, China; 3University of 4 California San Francisco, San Francisco, CA, US; UCSF, Dept of 134. Variability in SRS 22r outcome measures in non- and Orthopaedic Surgery, San Francisco, CA, US operatively treated patients with adolescent idiopathic FDA DEVICE/DRUG STATUS: This abstract does not discuss or scoliosis (AIS) greater than 40° include any applicable devices or drugs. Jared Crasto, MD1; W. Timothy Ward, MD2 1University of Pittsburgh Medical Center, Pittsburgh, PA, US; 131. Reaching minimal clinically important difference 2Childrens Hospital of Pittsburgh, Pittsburgh, PA, US (MCID) is not predictive of improved cost-per-QALY at FDA DEVICE/DRUG STATUS: This abstract does not discuss or two years in surgically treated adult spinal deformity include any applicable devices or drugs. patients (ASD) Richard A. Hostin Jr., MD1; Samrat Yeramaneni, MBBS, MS, PhD2; Khaled M. Kebaish, MD3; Emmanuel McNeely, MS, MHA4; Jeffrey 135. Multicenter prospective assessment of outcomes L. Gum, MD5; Douglas C. Burton, MD6; Christopher P. Ames, MD7; and complications associated with adult spinal deformity Justin S. Smith, MD, PhD8; Virginie Lafage, PhD9; Breton Line, BS10; surgery in 62 patients with severe global coronal Shay Bess, MD11; International Spine Study Group12 malalignment 1 2 1Southwest Scoliosis Institute, Dallas, TX, US; 2Sarah Cannon Thomas Buell, MD ; Justin S. Smith, MD, PhD ; Christopher I. 3 4 5 Research Institute, Dallas, TX, US; 3Johns Hopkins University, Shaffrey, MD ; Han Jo Kim, MD ; Eric O. Klineberg, MD ; Virginie 4 4 Baltimore, MD, US; 4The Johns Hopkins Hospital, Baltimore, Lafage, PhD ; Renaud Lafage, MSc ; Themistocles S. Protopsaltis, 6 7 8 MD, US; 5Norton Leatherman Spine Center, Louisville, KY, US; MD ; Peter G. Passias, MD ; Gregory M. Mundis Jr., MD ; Robert 9 10 6University of Kansas Medical Center, Kansas City, KS, US; K. Eastlack, MD ; Vedat Deviren, MD ; Michael P. Kelly, MD; Alan 11 12 7University of California, San Francisco, San Francisco, CA, US; H. Daniels, MD ; Jeffrey L. Gum, MD ; Alexandra Soroceanu, 13 14 15 8UVA Health System, Charlottesville, VA, US; 9Hospital for Special MD, MPH ; D. Kojo Hamilton, MD ; Munish C. Gupta, MD ; 16 17 Surgery, New York, NY, US; 10Denver International Spine Center, Douglas C. Burton, MD ; Richard A. Hostin Jr. , MD ; Khaled M. 18 19 4 Denver, CO, US; 11Denver, CO, US; 12Brighton, CO, US Kebaish, MD ; Robert A. Hart, MD ; Frank J. Schwab, MD ; Shay Bess, MD20; Christopher P. Ames, MD10; International Spine Study FDA DEVICE/DRUG STATUS: This abstract does not discuss or Group21 include any applicable devices or drugs. 1University of Virginia Neurosurgery , Charlottesville , VA, US; 2UVA Health System, Charlottesville, VA, US; 3Duke University , 132. Does navigation make spinal fusion for adolescent Durham, NC, US; 4Hospital for Special Surgery, New York, NY, US; idiopathic scoliosis safer? Insights from 17,400 cases 5UC, Davis School of Medicine, Sacramento, CA, US; 6Department from a national database of Orthopaedic Surgery, NYU Langone Orthopaedic Hospital, 7 Japsimran Kaur, BS1; Jayme Koltsov, PhD2; Kali Tileston, MD1; NYU Langone Health, New York, NY, US; NY Spine Institute, 8 Ivan Cheng, MD3; John S. Vorhies, MD4 NYU Langone Health, New York, NY, US; Scripps Clinic Medical 9 1 2 3 Group, Department of Orthopedics, La Jolla, CA, US; Scripps Stanford, CA, US; Redwood City, CA, US; Stanford University, 10 4 Clinic, San Diego, CA, US; University of California, San Francisco, Redwood City, CA, US; Stanford University Dept. of Orthopaedic San Francisco, CA, US; 11Warren Alpert Medical School of BU/RI Surgery, Stanford, CA, US Hospital, Providence, RI, US; 12Norton Leatherman Spine Center, FDA DEVICE/DRUG STATUS: This abstract does not discuss or Louisville, KY, US; 13University of Calgary, Calgary, Canada; include any applicable devices or drugs. 14University of Pittsburgh School of Medicine, Pittsburgh, PA, US; 15Washington University School of Medicine, St. Louis, MO, US; 16University of Kansas Medical Center, Kansas City, KS, US; 17Southwest Scoliosis Institute, Dallas, TX, US; 18Johns Hopkins University, Baltimore, MD, US; 19Swedish Neuroscience Institute, Seattle, WA, US; 20Denver, CO, US; 21Brighton, CO, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. Abstracts 69

136. Can supine radiographs help in saving fusion levels in 140. Complications and revision rates in minimally adolescent idiopathic scoliosis? invasive Mazor robotic-guided vs fluoroscopic-guided spinal fusions: the MIS ReFRESH prospective Andre Samuel, MD1; Yu-Cheng Yao, MD2; Kyle W. Morse, MD1; Virginie Lafage, PhD1; Roger F. Widmann, MD1; Han Jo Kim, MD1 comparative study 1 2 1Hospital for Special Surgery, New York, NY, US; 2Taipei Veterans Christopher R. Good, MD, FACS ; Samuel R. Schroerlucke, MD ; 3 4 General Hospital, Taipei, Taiwan Andrew F. Cannestra, MD, PhD ; Victor W. Hsu, MD ; Faissal Zahrawi, MD5; Jae Lim6; Hunaldo Villalobos, MD7; Pedro M. Ramirez, FDA DEVICE/DRUG STATUS: This abstract does not discuss or MD8; Thomas M. Sweeney II, MD, PhD9; Michael Y. Wang, MD10 include any applicable devices or drugs. 1Virginia Spine Institute, Reston, VA, US; 2Tabor Orthopedics, Memphis, TN, US; 3Lyerly Neurosurgery, Jacksonville, FL, US; 137. Study great expectations on the novel predictor of 4Rothman Institute, Willow Grove, PA, US; 5Celebration Minimally outcome after spinal surgery Invasive Spine Institute, Orlando, FL, US; 6Orlando, FL, US; 7Central 8 Xie En, MD Florida Neurosurgery Institute, Orlando, FL, US; Neurosurgery of Central Florida, Orlando, FL, US; 9Sarasota, FL, US; 10University of Hong Hui Hospital, Xi’an Jiaotong University College of Medicine, Miami, Dept of Neurosurgery, Miami, FL, US Xi’an, Shan Xi, China FDA DEVICE/DRUG STATUS: Mazor Renaissance Robotics FDA DEVICE/DRUG STATUS: This abstract does not discuss or (Approved for this indication) include any applicable devices or drugs. 141. The influence of glycemic control as measured by 138. Cervical radiographic parameters and patient hemoglobin A1c levels on complications following elective reported outcomes following Harrington instrumentation: lumbar spinal fusion a minimum 35-years follow-up Daniel Kiridly, MD, MBA1; Cesar Iturriaga, DO2; Ashna Joseph, 2 Noorullah Maqsoodi, BS1; Jarren A. Section, MD ; Adan Omar, BS3; Peter Olivares, BS4; Jesse M. Galina, BS3; Alexander M. Satin, 3 4 1 MD ; Aron Sulovari, BA ; Paul T. Rubery Jr., MD ; Emmanuel N. MD5; Jeffrey A. Goldstein, MD6; Dean C. Perfetti, MD, MPH7; 4 3 Menga, MD ; Addisu Mesfin, MD Austen Katz, MD8; Jeff S. Silber, MD, DC9; David A. Essig, MD10 1 2 Rochester, NY, US; Strong Memorial Hospital- University of 1Northwell Health Orthopaedic Surgery, New Hyde Park, NY, US; 3 Rochester, Benbrook, TX, US; University Of Rochester, Rochester, 2New Hyde Park, NY, US; 3Hempstead, NY, US; 4Northwell Health, 4 NY, US; University of Rochester School of Medicine and New Hyde Park, NY, US; 5American Pain & Wellness, Plano, TX, Dentistry, Rochester, NY, US US; 6Queens, NY, US; 7Department of Orthopedic Surgery, Long FDA DEVICE/DRUG STATUS: This abstract does not discuss or Island Jewish Medical Center, New Hyde Park, NY, US; 8Long include any applicable devices or drugs. Island Jewish Hospital, Queens, NY, US; 9Great Neck, NY, US; 10Northwell Health, Great Neck, NY, US 139. Adoption of enhanced recovery after surgery FDA DEVICE/DRUG STATUS: This abstract does not discuss or (ERAS) protocol for lumbar fusion decreases in-hospital include any applicable devices or drugs. postoperative opioid consumption

1 1 142. Effects of blood transfusions on gram-positive vs Ehsan Jazini, MD1; Colin M. Haines, MD ; Lindsay Orosz, PA-C ; Niteesh Bharara, MD1; Thomas C. Schuler, MD, FACS1; Omar gram-negative infections in a mouse model of spine Sohail, BA2; Rita Roy, MD2; Nathan Johnson2; Leah Y. Carreon, MD, implant infection MSc3; Christopher R. Good, MD, FACS1 Peter P. Hsiue, MD; Chad Ishmael, MD; Christopher Hart, MD; 1Virginia Spine Institute, Reston, VA, US; 2National Spine Health Clark J. Chen, BS; Kellyn R. Hori, BS; Howard Y. Park, MD; Zachary Foundation, Reston, VA, US; 3Norton Leatherman Spine Center, Burke, MD; Benjamin Kelley, MD; Nicholas Bernthal, MD Louisville, KY, US UCLA Department of Orthopaedic Surgery, Los Angeles, CA, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. include any applicable devices or drugs.

143. Optimization of a rat lumbar intervertebral disc degeneration model for low back pain Stephen Stephan, MD1; Juliane Glaeser, PhD2; Wafa Tawackoli, PhD3; Lea Kanim, MA4; Derek Ju, MD5; Zachary M. NaPier, MD6; Hyun W. Bae, MD7; Dmitriy Sheyn, PhD, MSc3 1Los Angeles, CA, US; 2Cedars-Sinai Medical Center, Board of Governors Regenerative Medicine Institute, Department of Orthopedics, Department of Surgery, Los Angeles, CA, US; 3Cedars-Sinai Medical Center, West Hollywood, CA, US; 4Spine Center, Cedars-Sinai Medical Center, Los Angeles, CA, US; 5Cedars-Sinai Medical Center, Los Angeles, CA, US; 6Cedars Sinai Orthopaedic Surgery, Los Angeles, CA, US; 7Spine Institute St. John’s Health Center, Los Angeles, CA, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. Abstracts 70

144. Concordance between patients’ and surgeons’ 148. Cost utility of revision surgery in cervical deformity expectations of cervical spine surgery patients with distal junctional kyphosis Roland Duculan, MD; Frank P. Cammisa, MD; Andrew A. Sama, Peter G. Passias, MD1; Waleed Ahmad2; Joshua Bell, MD3; MD; Alexander P. Hughes, MD; Darren R. Lebl, MD; Carol A. Katherine E. Pierce, BS4; Sara Naessig, BS5; Bassel G. Diebo, Mancuso, MD; Federico P. Girardi, MD MD6; Hamid Hassanzadeh, MD7; Justin S. Smith, MD, PhD8; 9 10 Hospital for Special Surgery, New York, NY, US Themistocles S. Protopsaltis, MD ; Virginie Lafage, PhD ; Christopher P. Ames, MD11 FDA DEVICE/DRUG STATUS: This abstract does not discuss or 1 2 include any applicable devices or drugs. NY Spine Institute, NYU Langone Health, New York, NY, US; New York, NY, US; 3University of Virginia, Department of Orthopaedics, Charlottesville, VA, US; 4NYU Spine Research Lab, New York, NY, 145. The impact of Michigan’s new opioid prescribing laws US; 5NYU Langone Hospital, New York NY, US; 6Department of on spine surgery patients: analysis of the Michigan Spine Orthopaedic Surgery, SUNY Downstate Medical Center, Brooklyn, Surgery Improvement Collaborative (MSSIC) NY, US; 7University of Virginia, Department of Orthopedic Surgery, Paul Park, MD1; Victor Chang, MD2; Jason M. Schwalb, MD3; David Charlottesville, VA, US; 8UVA Health System, Charlottesville, Nerenz, PhD4; Lonni R. Schultz, PhD5; Richard W. Easton, MD6; VA, US; 9Department of Orthopaedic Surgery, NYU Langone Osama Kashlan, MD7; Mark E. Oppenlander, MD8; Ilyas Aleem, Orthopaedic Hospital, NYU Langone Health, New York, NY, US; MD, MSc, FRCSC9 10Hospital for Special Surgery, New York, NY, US; 11University of 1University Of Michigan - Dept of Neurosurgery, Ann Arbor, MI, California, San Francisco, San Francisco, CA, US US; 2Henry Ford West Bloomfield Hospital, West Bloomfield, MI, FDA DEVICE/DRUG STATUS: This abstract does not discuss or US; 3Department of Neurological Surgery, University of Rochester, include any applicable devices or drugs. Rochester, NY, US; 4Henry Fords Health System, Detroit, MI, US; 5 6 Henry Ford Hospital, Detroit, MI, US; Michigan Orthopaedic 149. Increased risk of medical complications in patients Spine Surgeons, Rochester Hills, MI, US; 7University of Michigan, 8 with normal pressure hydrocephalus undergoing Ann Arbor, MI, US; University of Michigan Department of decompression for cervical myelopathy Neurosurgery, Ann Arbor, MI, US; 9University of Michigan Health System, Ann Arbor, MI, US Joshua Bell, MD1; Lawal Labaran2; Varun Puvanesarajah, MD3; Micheal Raad, MD4; Amit Jain, MD5; Hamid Hassanzadeh, MD6 FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. 1University of Virginia, Department of Orthopaedics, Charlottesville, VA, US; 2Richton Park, IL, US; 3Johns Hopkins Medicine, Baltimore, MD, US; 4Baltimore, MD, US; 5Dept of 146. Structural allograft vs polyetheretherketone (PEEK) Orthopaedic Surgery, Baltimore, MD, US; 6University of Virginia, implants in patients undergoing spinal fusion surgery: a Department of Orthopedic Surgery, Charlottesville, VA, US systematic review and meta analysis FDA DEVICE/DRUG STATUS: This abstract does not discuss or Nida Fatima, MD, MBBS; Elie Massaad, MD; Muhamed Hadzipasic, include any applicable devices or drugs. MD, PhD; Ganesh M. Shankar, MD, PhD; John H. Shin, MD Department of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, US 150. Outpatient vs inpatient anterior lumbar surgery: a multisite, comparative analysis of patient safety FDA DEVICE/DRUG STATUS: This abstract does not discuss or measures include any applicable devices or drugs. Ehsan Saadat, MD1; Anthony Ma, BS2; Jason M. Cuellar, MD, PhD3; Patrick S. Hill, MD4; Todd H. Lanman, MD3; Edward K. Nomoto, 147. Neurologic complications following adult spinal MD5; Stephen Stephan, MD1; Michael Eng, MD6; Brian Perri, DO5; deformity and impact on health-related quality of life Albert Wong, MD5; 2 measures Alexandre Rasouli, MD 1Los Angeles, CA, US; 2Rasouli Spine, Los Angeles, CA, US; Eric O. Klineberg, MD1; Lauren Agatstein, MA2; Renaud Lafage, 3Beverly Hills, CA, US; 4DOCS Spine & Orthopedics, New York, NY, MSc3; Justin S. Smith, MD, PhD4; Christopher I. Shaffrey, MD5; US; 5Beverly Hills Spine Surgery, Los Angeles, CA, US; 6Cedars Gregory M. Mundis Jr. , MD6; Han Jo Kim, MD3; Munish C. Gupta, Sinai Medical Center, Los Angeles, CA, US MD7; Michael P. Kelly, MD; Christopher P. Ames, MD9; Peter G. Passias, MD9; Themistocles S. Protopsaltis, MD10; Douglas C. FDA DEVICE/DRUG STATUS: This abstract does not discuss or Burton, MD11; Frank J. Schwab, MD3; Shay Bess, MD12; Virginie include any applicable devices or drugs. Lafage, PhD3; International Spine Study Group13 1UC, Davis School of Medicine, Sacramento, CA, US; 2University 151. A cadaveric precision and accuracy analysis of of California, Davis, Sacramento, CA, US; 3Hospital for Special augmented reality mediated percutaneous pedicle Surgery, New York, NY, US; 4UVA Health System, Charlottesville, implant insertion 5 6 VA, US; Duke University, Durham, NC, US; Scripps Clinic Medical 1; Frank M. Phillips, MD2; Kornelis A. 7 Camilo A. Molina, MD Group, Department of Orthopedics, La Jolla, CA, US; Washington Poelstra, MD, PhD3; Matthew Colman, MD2; Larry T. Khoo, MD4 University School of Medicine, St. Louis, MO, US; 8University 1 2 of California, San Francisco, San Francisco, CA, US; 9NY Spine Johns Hopkins Hospital, Baltimore, MD, US; Midwest 3 Institute, NYU Langone Health, New York, NY, US; 10Department Orthopaedics At Rush, Chicago, IL, US; The Robotic Spine 4 of Orthopaedic Surgery, NYU Langone Orthopaedic Hospital, NYU Institute of Silicon Valley, Los Gatos, CA, US; Los Angeles, CA, US Langone Health, New York, NY, US; 11University of Kansas Medical FDA DEVICE/DRUG STATUS: This abstract does not discuss or Center, Kansas City, KS, US; 12Denver, CO, US; 13Brighton, CO, US include any applicable devices or drugs. FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. Abstracts 71

152. Comparison of current health insurance provider 156. Operative vs nonoperative treatment for adult criteria for coverage of lumbar discectomy procedures symptomatic lumbar scoliosis at 5-6-year follow-up: outcomes and impact of related serious adverse events Ari J. Holtzman, MD1,2,3; Zachary T. Sharfman, MD, MS1,2,3; Daniel Berman, MD1,2,3; Nathaniel L. Tindel, MD2,3 Justin S. Smith, MD, PhD1; Michael P. Kelly, MD; Elizabeth Yanik, 2 3 4 1Montefiore Medical Center, Department of Orthopedic PhD, MSc ; Christine R. Baldus, RN ; Thomas Buell, MD ; Jon D. 5 6 Surgery, Bronx, NY, US; 2Jacobi Medical Center, Department of Lurie, MD, MS ; Charles Edwards Sr., MD ; Steven D. Glassman, 7 17 8 Orthopaedic Surgery, Bronx, NY, US; 3Albert Einstein College of MD ; Lawrence G. Lenke, MD ; Oheneba Boachie-Adjei, MD ; 9 7 Medicine, Bronx, NY, US Jacob M. Buchowski, MD, MS ; Leah Y. Carreon, MD, MSc ; Charles H. Crawford III, MD7; Stephen J. Lewis, MD10; Stefan FDA DEVICE/DRUG STATUS: This abstract does not discuss or Parent, MD; Virginie Lafage, PhD8; Munish C. Gupta, MD11; Han include any applicable devices or drugs. Jo Kim, MD8; Christopher P. Ames, MD12; Shay Bess, MD13; Frank J. Schwab, MD8; Christopher I. Shaffrey, MD14; Keith H. Bridwell, 153. Radiographic comparison between conventional MD15; International Spine Study Group16 laminectomy and a new technique for posterior lumbar 1UVA Health System, Charlottesville, VA, US; 2Washington decompression: a cadaveric study University in St. Louis, St. Louis, MO, US; 3Washington Bo Zhang, MD1; Andrew B. Harris2; Alex Solomon, MD2; Sang-Hun University, Department of Orthopedics, St. Louis, MO, US; 4 Lee, MD, PhD4; Floreana K. Naef, MD4; Khaled M. Kebaish, MD4 University of Virginia Neurosurgery, Charlottesville, VA, US; 5 6 1 2 Dartmouth College, Lebanon, NH, US; Baltimore, MD, US; Johns Hopkins Medicine, Baltimore, MD, US; Johns Hopkins 7 8 3 Norton Leatherman Spine Center, Louisville, KY, US; Hospital Department of Radiology, Baltimore, MD, US; Johns Hopkins for Special Surgery, New York, NY, US; 9Washington University University, Dept. of Orthopedic surgery, Baltimore, MD, US; 10 4 School of Medicine, Saint Louis, MO, US; Toronto Western Johns Hopkins University, Baltimore, MD, USA Hospital, Toronto, ON, Canada; 11Washington University School FDA DEVICE/DRUG STATUS: This abstract does not discuss or of Medicine, St. Louis, MO, US; 12University of California, San include any applicable devices or drugs. Francisco, San Francisco, CA, US; 13Denver, CO, US; 14Duke University, Durham, NC, US; 15Washington University In St. Louis School of Medicine, Saint Louis, MO, US; 16Brighton, CO, US; 154. The use of autologous free vascularized fibula grafts 17 in reconstruction of the mobile spine following tumor Columbia University Department of Orthopedic Surgery, New resection: illustrated surgical technique and outcomes York, NY, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or Michiel Bongers, MD1; Paul T. Ogink, MD2; Brett D. Rosenthal, MD; include any applicable devices or drugs. Joseph H. Schwab, MD3 1Boston, MA, US; 2Orthopaedic Spine Center, Boston, MA, US; 3Massachusetts General Hospital, Boston, MA, US 157. Do cells matter? In vitro and in vivo analysis of autograft viability FDA DEVICE/DRUG STATUS: This abstract does not discuss or 1 2 include any applicable devices or drugs. Gregory M. Mundis Jr., MD ; Frank Vizesi, PhD, PhD ; Nick Russell, PhD3; Jiawei He, PhD2 1Scripps Clinic Medical Group, Department of Orthopedics, La 155. Safer way for vertebroplasty under fluid mechanics 2 3 theory Jolla, CA, US; SeaSpine, Carlsbad, CA, US; Carlsbad, CA, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or Hsuan Yu Chen, MD1,2; Yen-Po Lin, MD3; Han Ying Wang, MD3; include any applicable devices or drugs. Feng Huei Lin, PhD1; Po-Quang Chen, MD, PhD4; Ding-cheng Chan, MD, PhD, FACP5; Tze Hong Wong, MD, PhD3; Ming-Hsiao Hu, MD, PhD4 158. The effects of a single injection of NTG-101 1Institute of Biomedical Engineering, National Taiwan University, upon neurotrophin expression in a canine model of Taipei, Taiwan; 2Department of Orthopedic Surgery, National degenerative disc disease Taiwan University Hospital, Hsin-Chu Biomedical Park Branch, William Mark Erwin, DC, PhD1; Ajay Matta, PhD2; Muhammad Zia Taipei, Taiwan; 3Department of Orthopedic Surgery, National Karim, DVM2; Hoda Gerami, BS2; Bettina Zoe Benigno, BS2

Taiwan University Hospital, Hsin-Chu Branch, Taipei, Taiwan; 1 2 4 Dept of Surgery, Univ of Toronto, Toronto, ON, Canada; Notogen, Department of Orthopedic Surgery, Natinal Taiwan University Toronto, ON, Canada Hospital, Taipei, Taiwan; 5National Taiwan University Hospital Chu-Tung Branch, Hsinchu County, Taiwan FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. Abstracts 72

159. Efficacy of surgical decompression in patients with 162. Two-level cervical disc replacement using a PEEK-on- cervical spondylotic myelopathy results of the Canadian ceramic device: prospective outcome data from an FDA prospective multi-center study IDE trial Mohammed Karim, MD1; Bradley Jacobs, MD, FRCSC2; Michael Domagoj Coric, MD1; Richard D. Guyer, MD2; Pierce D. Nunley, G. Johnson, MD, FRCSC3; Christopher S. Bailey, MD, FRCSC4; MD3; K. Brandon Strenge, MD4; Donna D. Ohnmeiss, PhD5 5 6 Sean D. Christie, MD ; Jérôme Paquet, MD, FRCSC ; Andrew 1Carolina Neurosurgery & Spine Associates, Charlotte, NC, US; 7 2 Nataraj, MSc, MD, FRCSC ; David W. Cadotte, MD, PhD ; Jefferson 2Center for Disc Replacement at Texas Back Institute, Plano, 8 9 Wilson, MD, PhD, FRCSC ; Neil A. Manson, MD, FRCSC ; Hamilton TX, US; 3Spine Institute of Louisiana, Shreveport, LA, US; 4The 10 2 Hall, MD, FRCSC ; Kenneth C. Thomas, MD, FRCS ; Raja Y. Orthopaedic Institute of Western Kentucky, Paducah, KY, US; 11 12 Rampersaud, MD, FRCSC ; Greg McIntosh, BS ; Charles G. 5Texas Back Institute, Plano, TX, US Fisher, MD, FRCSC, MHS1; Nicolas Dea, MD, MSc, FRCSC1 FDA DEVICE/DRUG STATUS: Simplify disc (Investigational/Not 1 Combined Neurosurgery and Orthopaedic Spine Program, approved) University of British Columbia, Vancouver, BC, Canada; 2Department of Clinical Neurosciences, Division of Neurosurgery, Department of Radiology, Hotchkiss Brain Institute, University of 163. Predicting severe clinically relevant distal junctional Calgary, Calgary, AB, Canada; 3Department of Surgery, Section kyphosis development following adult cervical deformity of Orthopaedics and Neurosurgery, University of Manitoba, surgery with further distinction from mild asymptomatic Winnipeg, MB, Canada; 4Department of Surgery, Western episodes 5 University, London, ON, Canada; Division of Neurosurgery, Peter G. Passias, MD1; Sara Naessig, BS2; Virginie Lafage, PhD3; 6 Dalhousie University, Halifax, NS, Canada; Department of Renaud Lafage, MSc3; Bassel G. Diebo, MD4; Themistocles S. Orthopaedics, Centre Hospitalier Universitaire de Quebec, Protopsaltis, MD5; Han Jo Kim, MD3; Robert K. Eastlack, MD6; 7 Quebec, QC, Canada; Division of Neurosurgery, Faculty of Alexandra Soroceanu, MD, MPH7; Eric O. Klineberg, MD8; Robert Medicine and Dentistry, University of Alberta, Edmonton, Alberta, A. Hart, MD9; Douglas C. Burton, MD10; Shay Bess, MD11; Frank 8 Canada; Divison of Neurosurgery, Department of Surgery, J. Schwab, MD3; Christopher I. Shaffrey, MD12; Justin S. Smith, 9 University of Toronto, Toronto, ON, Canada; Canada East Spine MD, PhD13; Christopher P. Ames, MD14; International Spine Study Centre, Saint John Regional Hospital, Saint John, NB, Canada; Group15 10 Department of Surgery, University of Toronto, Toronto, ON, 1 2 Canada; 11Division of Orthopaedic Surgery and Neurosurgery, NY Spine Institute, NYU Langone Health, New York, NY, US; NYU Langone Hospital, New York NY, US; 3Hospital for Special Surgery, Department of Surgery, University of Toronto, Toronto, ON, 4 Canada; 12Canadian Spine Society, Toronto, ON, Canada New York, NY, US; Department of Orthopaedic Surgery, SUNY Downstate Medical Center, Brooklyn, NY, US; 5Department of FDA DEVICE/DRUG STATUS: This abstract does not discuss or Orthopaedic Surgery, NYU Langone Orthopaedic Hospital, NYU include any applicable devices or drugs. Langone Health, New York, NY, US; 6Scripps Clinic, San Diego, CA, US; 7University of Calgary, Calgary, Canada; 8UC, Davis School of 9 160. Fusion for fracture has no place in a lumbar fusion Medicine, Sacramento, CA, US; Swedish Neuroscience Institute, 10 bundled payment model: an analysis of Medicare Seattle, WA, US; University of Kansas Medical Center, Kansas 11 12 beneficiaries City, KS, US; Denver, CO, US; Duke University , Durham, NC, US; 13UVA Health System, Charlottesville, VA, US; 14University of 1 2 2 Azeem T. Malik, MBBS ; Khaled Himed, BS ; Joseph Drain, MD ; California, San Francisco, San Francisco, CA, US; 15Brighton, CO, US Elizabeth Yu, MD2; Jeffery Kim, MD1; Safdar N. Khan, MD1 FDA DEVICE/DRUG STATUS: This abstract does not discuss or 1 The Ohio State University Wexner Medical Center, Columbus, include any applicable devices or drugs. OH, US; 2Columbus, OH, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or 164. Development and validation of machine learning include any applicable devices or drugs. algorithms for predicting mortality following surgery for metastatic spine tumors: metastatic mortality scoring 161. Cervical disc replacement using a PEEK-on-ceramic system (MMS) implant: prospective data from seven sites participating Nida Fatima, MD, MBBS1; Hui Zheng, PhD2; Elie Massaad, MD1; in an FDA IDE trial for single-level surgery Muhamed Hadzipasic, MD, PhD1; Ganesh M. Shankar, MD, PhD1; Domagoj Coric, MD1; Richard D. Guyer, MD2; Cameron N. John H. Shin, MD1 3 4 5 Carmody, MD ; Rick C. Sasso, MD ; Michael J. Musacchio, MD ; 1Department of Neurosurgery, Massachusetts General Hospital, 6 7 Hyun W. Bae, MD ; Donna D. Ohnmeiss, PhD Harvard Medical School, Boston, MA, US; 2Department of Bio 1Carolina Neurosurgery & Spine Associates, Charlotte, NC, US; Statistics, Massachusetts General Hospital, Harvard Medical 2Center for Disc Replacement at Texas Back Institute, Plano, TX, School, Boston, MA, US 3 4 US; Texas Spine Consultants, Addison, TX, US; Indiana Spine FDA DEVICE/DRUG STATUS: This abstract does not discuss or 5 Group, Carmel, IN, US; NorthShore University HealthSystem, include any applicable devices or drugs. Evanston, IL, US; 6Spine Institute St. John’s Health Center, Los Angeles, CA, US; 7Texas Back Institute Research Foundation, Plano, TX, US FDA DEVICE/DRUG STATUS: Simplify (Investigational/Not approved) Abstracts 73

165. Impact of a centralized spinal orthoses program on 169. To prevent PJK in Scheuermann’s Kyphosis restore cost of care in the hospital setting kyphosis to patient’s PI value and choose proximal UIV Susan Willey, MS, PT1; James Lenk, BS, MPT1; Linda Waters, PT1; Vishal Sarwahi, MD1; Jesse M. Galina, BS2; Sayyida S. Hasan, BS3; Jonathan Cayce, PhD, MS2; Charles French, MBA2 Jeffrey A. Goldstein, MD4; Alexander M. Satin, MD5; Yungtai Lo, 6 7 1Ascension Via Christi, Wichita, KS, US; 2DeRoyal Industry, Powell, PhD ; Terry D. Amaral, MD TN, US 1North Shore LIJ Health System, New Hyde Park, NY, US; 2New 3 FDA DEVICE/DRUG STATUS: DeRoyal Spinal Orthoses (Approved Hyde Path, NY, US; Cohen Children’s Medical Center, New Hyde 4 5 for this indication) Park, NY, US; Queens , NY, US; American Pain & Wellness, Plano, TX, US; 6Albert Einstein College of Medicine, Bronox, NY, US; 7Northwell Health, Lake Success, NY, US 166. Effectiveness of epidural amniotic fluid injection for FDA DEVICE/DRUG STATUS: This abstract does not discuss or low back pain include any applicable devices or drugs. Glenn R. Buttermann, MD1; Louis C. Saeger, MD2; Matthew G. Thorson, MD3 170. Radiculitis: assessing the risk of biologic use in 1 2 Midwest Spine Institute, Stillwater, MN, US; Premier Spine and minimally invasive transforaminal lumbar interbody 3 Pain Clinics, Minneapolis, MN, US; Advanced Spine and Pain fusions Clinics, Edina, MN, US Carolyn Stickley, BS1; Erik Wang, BA1; Ethan W. Ayres, MPH1; FDA DEVICE/DRUG STATUS: This abstract does not discuss or Constance Maglaras, PhD2; Charla R. Fischer, MD2; Jonathan R. include any applicable devices or drugs. Stieber, MD3; Martin Quirno, MD3; Themistocles S. Protopsaltis, MD1; Peter G. Passias, MD4; Aaron J. Buckland, MBBS, FRACS1 167. Validation of the ACS-NSQIP risk index in a 1Department of Orthopedic Surgery, NYU Langone Health, New prospective, multicenter adult spinal deformity database York, NY, US; 2New York, NY, US; 3New York, NY, US; 4NY Spine Katherine E. Pierce, BS1; Peter G. Passias, MD2; Virginie Lafage, Institute, NYU Langone Health, New York, NY, US PhD3; Renaud Lafage, MSc3; Gregory M. Mundis Jr., MD4; Juan FDA DEVICE/DRUG STATUS: This abstract does not discuss or S. Uribe, MD5; Han Jo Kim, MD3; Themistocles S. Protopsaltis, include any applicable devices or drugs. MD6; Alan H. Daniels, MD7; Robert A. Hart, MD8; Douglas C. Burton, MD9; Christopher I. Shaffrey, MD10; Frank J. Schwab, MD3; Christopher P. Ames, MD11; Justin S. Smith, MD, PhD12; Shay Bess, 171. Does conflict of interest affect the reported fusion MD13; Eric O. Klineberg, MD14; International Spine Study Group15 rates with bone graft extenders? 1NYU Spine Research Lab, New York, NY, US; 2NY Spine Yu-Po Lee, MD; Garwin Chin, MD; Joshua Lee; Noah Zhang; Saif Institute, NYU Langone Health, New York, NY, US; 3Hospital Aldeen Farhan, MD; P D. Kiester, MD; Charles D. Rosen, MD; Nitin for Special Surgery, New York, NY, US; 4Scripps Clinic Medical N. Bhatia, MD Group, Department of Orthopedics, La Jolla, CA, US; 5Barrow UC Irvine Medical Center, Orange, CA, US 6 Neurological Institute, Phoenix, AZ, US; Department of FDA DEVICE/DRUG STATUS: This abstract does not discuss or Orthopaedic Surgery, NYU Langone Orthopaedic Hospital, include any applicable devices or drugs. NYU Langone Health, New York, NY, US; 7Warren Alpert Medical School of BU/RI Hospital, Providence, RI, US; 8Swedish Neuroscience Institute, Seattle, WA, US; 9University of Kansas 172. Assessment of spinopelvic parameters following Medical Center, Kansas City, KS, US; 10Duke University, Durham, stand alone decompression in the patients with lumbar NC, US; 11University of California, San Francisco, San Francisco, spinal stenosis 12 13 CA, US; UVA Health System, Charlottesville, VA, US; Denver, Naveed Nabizadeh, MD1; Mohammad E. Majd, MD2; Sam Bemani, 14 CO, US; UC, Davis School of Medicine, Sacramento, CA, US; MD3; Farshad Nikouei, MD3; Hasan Ghandhari, MD3 15Brighton, CO, US 1Norton Leatherman Spine Center, Louisville, KY, US; 2Baptist FDA DEVICE/DRUG STATUS: This abstract does not discuss or Health Floyd, Indiana University, New Albany, IN, US; 3Bone and include any applicable devices or drugs. Joint Reconstruction Center, Iran University of Medical Sciences, Tehran, Iran 168. Factors associated with the failure to meet 90-day FDA DEVICE/DRUG STATUS: This abstract does not discuss or estimated survival after the surgical treatment of spinal include any applicable devices or drugs. metastases Eric Vess, MD; Matthew St. John, MD, MS; Noorullah Maqsoodi, 173. The timing and incidence of surgical intervention BS; Caroline P. Thirukumaran, MBBS, MHA, PhD; Addisu Mesfin, following diagnosis of lumbar disc herniation at military MD treatment facilities University of Rochester, Department of Orthopaedics, Rochester, Ashley Anderson, MD1; Alfred J. Pisano, MD1; Matthew Braswell, NY, US MD2; Nora Watson, PhD1; Melvin D. Helgeson, MD1; Daniel Brooks, FDA DEVICE/DRUG STATUS: This abstract does not discuss or PhD1; Scott Wagner, MD1 include any applicable devices or drugs. 1USU-Walter Reed National Military Medical Center, Bethesda, MD, US; 2Charlotte Medical Center, Charlotte, NC, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. Abstracts 74

174. Generic measures of frailty assessment may be 178. Minimally invasive surgery mitigates but does not inadequate for the heterogeneity of spine surgery eliminate adverse perioperative outcomes for frail TLIF patients; a systematic review of frailty indices used in Sara Naessig, BS1; Katherine E. Pierce, BS2; Carlos Leon, BS3; Jack spine surgery Zhong, BA4; Carolyn Stickley, BS5; Constance Maglaras, PhD6; Jamie R. Wilson, BA, MD, FRCS1; Robert A. Ravinsky, MD, MPH, Brooke K. O’Connell, MS6; Bassel G. Diebo, MD7; Claire White- FRCSC2; Jetan H. Badhiwala, MD3; Fan Jiang, MD4; Michael G. Dzuro, BA8; Shaleen N. Vira, MD9; Steven Hale, MD10; Themistocles Fehlings, MD, PhD, FRCSC4 S. Protopsaltis, MD11; Aaron J. Buckland, MBBS, FRACS12; Peter 13 1Dept of Neurosurgery, University of Nebraska Medical Center, G. Passias, MD Omaha, NE, US; 2Toronto, ON, Canada; 3Division of Neurosurgery, 1NYU Langone Hospital, New York NY, US; 2NYU Spine Research Department of Surgery, University of Toronto, Toronto, ON, Lab, New York, NY, US; 3NYU Langone Medical Center, New Canada; 4Toronto Western Hospital, Toronto, ON, Canada York City, NY, US; 4NYU langone Spine Research Center, New 5 FDA DEVICE/DRUG STATUS: This abstract does not discuss or York, NY, US; Department of Orthopedic Surgery, NYU Langone 6 7 include any applicable devices or drugs. Health, New York, NY, US; New York, NY, US; Department of Orthopaedic Surgery, SUNY Downstate Medical Center, Brooklyn, NY, US; 8SpinecareNYC Orthopedic, New York, NY, US; 175. Discrepancy in patient-reported pain using the 9Department of Orthopaedic Surgery, UT Southwestern Medical numeric pain scale and a percentage change to quantify Center, Dallas, TX, US; 10Spine Care NYC, New York City, NY, US; treatment effectiveness after pain injections 11Department of Orthopaedic Surgery, NYU Langone Orthopaedic 12 Barthelemy Liabaud, MD1; Puneet Ralhan, DO2; Sirish Khanal, BS3; Hospital, NYU Langone Health, New York, NY, US; Department Andrew Beaufort, MD4; Joshua D. Lavian, BA3; Sanjeev Agarwal, of Orthopedic Surgery, NYU Langone Orthopedic Hospital, NYU 13 MD5 Langone Health , New York, NY, US; NY Spine Institute, NYU Langone Health, New York, NY, US 1SUNY Downstate, Brooklyn, NY, US; 2Desert Spine and Sports Physicians, Phoenix, AZ, US; 3SUNY Downstate Medical Center, FDA DEVICE/DRUG STATUS: This abstract does not discuss or Brooklyn, NY, US; 4SUNY Downstate Health Sciences University, include any applicable devices or drugs. Brooklyn, NY, US; 5Comprehensive Spine Center, Brooklyn, NY, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or 179. Propensity-matched analysis of 1,062 patients include any applicable devices or drugs. following minimally invasive vs open sacroiliac joint fusion Alexander Ballatori, BA1; Shane Shahrestani, MS2; Xiao Chen, 176. Thoracolumbar interfascial plain (TLIP) block and BA1; Andy Ton, BS3; Jeffrey C. Wang, MD4; Zorica Buser, PhD5 intrathecal fentanyl injection results in an opioid-free 1 2 3 peri- and postoperative recovery and early ambulation Los Angeles, CA, US; Yorba Linda, CA, US; Anaheim, CA, 4 5 after percutaneous lumbar spine surgery US; USC Spine Center, Los Angeles, CA, US; Keck School of Medicine, University of Southern California, Los Angeles, CA, US Christian Morgenstern, MD, PhD, MSc1; Carlos Rafael Ramirez Paesano, PhD, MD2; Albert Juanola, MD3; Rudolf Morgenstern, FDA DEVICE/DRUG STATUS: This abstract does not discuss or MD, PhD4 include any applicable devices or drugs. 1Centro Médico Teknon, Barcelona, Spain; 2Centro Médico Teknon. Dpto. Anesthesia (Anestalia), Barcelona, Barcelona, 180. Over reporting disc herniation in lumbar spine MRI’s Spain; 3Centro Médico Teknon., Barcelona, Barcelona, Spain; performed for patients with spondylolisthesis 4Instituto Morgenstern S.L., Esplugues de Llobregat, Barcelona, Hassan Semaan, MD1; Bryan Curnutte, MD1; Tawfik Obri, MD2; Spain Mazzin Elsamaloty, BS3; Joud Obri, BS4; Hossein K. Elgafy, MD, 5 FDA DEVICE/DRUG STATUS: Fentanyl (Approved for this FRCSC, MBA indication), Zalviso (Approved for this indication), Bupivacaine 1Toledo, OH, US; 2Tawfik Obri, Maumee, OH, US;3 University of (Approved for this indication), Globus RISE (Approved for this Toledo, Toledo, OH, US; 4Maumee, OH, US; 5University of Toledo indication) Medical Center, Toledo, OH, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or 177. Vertebral height restoration following painful include any applicable devices or drugs. vertebral compression fracture: an international multicenter experience using spine jack 181. Spinal shortening osteotomy as a major factor to Devin Bageac, BS, BA; Reade De Leacy, MBBS improve associated syrinx in scoliotic patient with Chiari 1 Mount Sinai Hospital New York, NY, US Malformation (CM-1) 1 1 1 FDA DEVICE/DRUG STATUS: SpineJack (Not approved for this Zhi Zhao, MD ; Yingsong Wang, MD ; Jing-Ming Xie, MD ; Zhiyue 1 1 1 2 1 indication) Shi, MD ; Ni Bi, MD ; Tao Li, MD ; Quan Li, MD ; Ying Zhang, MD 1Department of Orthopaedics, 2nd Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, China; 2Kunming, China FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. Abstracts 75

182. Limited cost benefit of lateral interbody fusion (LIF) 187. Compared to gold standard bone SPECT/CT showed for adult spinal deformity (ASD) surgery in Japan superior accuracy in detecting pseudarthrosis Tatsuya Yamamoto, MD1; Mitsuru Yagi, MD, PhD2; Satoshi Suzuki, Richard W. Easton, MD1; Nai-Wei Chen, PhD2; Matthew Lipphardt, MD1; Osahiko Tsuji, MD, PhD3; Narihito Nagoshi, MD, PhD4; Ejiiro MD2; Truman Silvasi, MD2; Cecile Pestano, RN, BSN, CCRP1 5 6 7 Okada, MD ; Nobuyuki Fujita, MD ; Masaya Nakamura, MD, PhD ; 1Michigan Orthopaedic Spine Surgeons, Rochester Hills, MI, US; 8 9 Morio Matsumoto, MD ; Kota Watanabe, MD 2Beaumont Health, Royal Oak, MI, US 1 2 Keio University, Tokyo, Japan; Department of Orthopedic FDA DEVICE/DRUG STATUS: This abstract does not discuss or Surgery, Keio University School of Medicine, Tokyo, Japan; include any applicable devices or drugs. 3Saitama, Japan; 4Toronto Western Hospital, Toronto, ON, Canada; 5Saiseikai Central Hospital, Tokyo, Japan; 6Fujita Health Univ., Aichi, Japan; 7Department of Orthopedic Surgery, Keio 188. The safety and efficacy of hydrogen peroxide in University School of Medicine, Shinjuku, Tokyo, Japan; 8Keio controlling blood loss and surgical site infection after University School of Medicine, Tokyo, Japan; 9Keio University, multi-segmental lumbar spine surgery: a retrospective, Keio, Japan case-controlled study of 2,626 patients FDA DEVICE/DRUG STATUS: This abstract does not discuss or Jun-Song Yang, MD1; Peng Liu, MD2; Tuan-Jiang Liu, MD3; Ding- include any applicable devices or drugs. Jun Hao, MD1 1Department of Spine Surgery, Honghui Hospital, Xi’an Jiaotong 2 183. Operation is no better than nonoperative care in University, Xi’an, China; Honghui Hospital, Xi’an Jiaotong 3 improving pain and disability in chronic low back pain: University, Xi’an, Shaanxi, China; Xi’an, China long term results of randomized controlled trials of FDA DEVICE/DRUG STATUS: This abstract does not discuss or western China include any applicable devices or drugs. Xie En, MD Hong Hui Hospital, Xi’an Jiaotong University College of Medicine, 189. Spinal stenosis grading in magnetic resonance Xi’an, Shan Xi, China imaging using deep convolutional neural networks FDA DEVICE/DRUG STATUS: This abstract does not discuss or Suk-Joong Lee, MD1; Hyun-Joo Lee, MD, PhD2 include any applicable devices or drugs. 1Dongsan Medical Center, Keimyung University, Daegu, Republic of Korea; 2Kyungpook National University Hospital, Daegu, 184. Effect of end plate contact surface topology and Republic of Korea structural modulus on subsidence: comparison of two FDA DEVICE/DRUG STATUS: This abstract does not discuss or 3D-printed titanium lateral interbody devices include any applicable devices or drugs. Ali Kiapour, PhD1; Puya Alikhani, MD2 1Boston, MA, US; 2Tampa, FL, US 190. Assessing the impact of surgical and patient factors on recovery kinetics after ASD surgery FDA DEVICE/DRUG STATUS: LSTS Lateral Fixation Device (Approved for this indication), Modulus Lateral Fixation Device Brian J. Neuman, MD1; Rahul Sachdev, BS1; Emmanuel McNeely, (Approved for this indication) MS, MHA2; Eric O. Klineberg, MD3; Peter G. Passias, MD4; Themistocles S. Protopsaltis, MD5; Justin S. Smith, MD, PhD6; Christopher P. Ames, MD7; Shay Bess, MD8; Khaled M. Kebaish, 185. A novel testing methodology to quantify MD9; International Spine Study Group10 multidirectional flexibility properties of the lumbar spine 1Baltimore, MD, US; 2The Johns Hopkins Hospital, Baltimore, 1 1 Daina M. Brooks, BS ; Bryan W. Cunningham, PhD ; Mohit M. MD, US; 3UC, Davis School of Medicine, Sacramento, CA, US; 1 2 3 Kukreja, MD, MS, DNB ; Kenneth Mullinix, BS ; Nicholas Rolle, BS ; 4NY Spine Institute, NYU Langone Health, New York, NY, US; 3 P. Justin Tortolani, MD 5Department of Orthopaedic Surgery, NYU Langone Orthopaedic 1Medstar Union Memorial Hospital, Baltimore, MD, US; 2Audubon, Hospital, NYU Langone Health, New York, NY, US; 6UVA Health PA, US; 3Baltimore, MD, US System, Charlottesville, VA, US; 7University of California, San 8 9 FDA DEVICE/DRUG STATUS: This abstract does not discuss or Francisco, San Francisco, CA, US; Denver, CO, US; Johns 10 include any applicable devices or drugs. Hopkins University, Baltimore, MD, US; Brighton, CO, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. 186. Comparison of a 3D printed truss-based lateral interbody device to an annular lateral interbody device for resistance to subsidence: a cadaveric study Ali Kiapour, PhD1; Vijay K. Goel, PhD2; Puya Alikhani, MD3 1Boston, MA, US; 2University of Toledo, Toledo, OH, US; 3Tampa, FL, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. Abstracts 76

191. Multiple revision surgeries are associated with 194. The fate of patients with early postoperative surgical reduced patient satisfaction in adult spinal deformity site infections following instrumented lumbar fusion Wesley M. Durand1; Alan H. Daniels, MD2; Renaud Lafage, Arya Ahmady, MD1; Zachary L. Gordon, MD2; Nicholas U. Ahn, MSc3; Peter G. Passias, MD4; Han Jo Kim, MD3; Themistocles MD3; Christina W. Cheng, MD4; Christopher G. Furey, MD5 5 3 S. Protopsaltis, MD ; Virginie Lafage, PhD ; Justin S. Smith, MD, 1Ann Arbor, MI, US; 2University Hospitals Cleveland Medical 6 7 8 PhD ; Christopher I. Shaffrey, MD ; Munish C. Gupta, MD ; Eric Center, Dept of Orthopaedic Surgery, Cleveland, OH, US; 9 3 10 O. Klineberg, MD ; Frank J. Schwab, MD ; Jeffrey L. Gum, MD ; 3University Hospital of Cleveland, Department of Orthopedic 11 12 Gregory M. Mundis Jr., MD ; Robert K. Eastlack, MD ; Khaled Surgery, Cleveland, OH, US; 4University Hospitals Cleveland 13 14 M. Kebaish, MD ; Alexandra Soroceanu, MD, MPH ; Richard Medical Center, Cleveland, OH, US; 5Case Western Reserve 15 16 17 A. Hostin Jr., MD ; Douglas C. Burton, MD ; Shay Bess, MD ; University, Cleveland, OH, US Christopher P. Ames, MD18; Robert A. Hart, MD19; D. Kojo Hamilton, MD20; International Spine Study Group21 FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. 1Brown University, Alpert Medical School, Providence, RI, US; 2Warren Alpert Medical School of BU/RI Hospital, Providence, RI, US; 3Hospital for Special Surgery, New York, NY, US; 4NY Spine 195. Fostering physical activity after complex lumbar Institute, NYU Langone Health, New York, NY, US; 5Department spine surgery: long-term results of a randomized trial of Orthopaedic Surgery, NYU Langone Orthopaedic Hospital, Roland Duculan, MD; Manuela Rigaud, MS; Frank P. Cammisa, 6 NYU Langone Health, New York, NY, US; UVA Health System, MD; Andrew A. Sama, MD; Alexander P. Hughes, MD; Carol A. 7 Charlottesville, VA, US; Duke University, Durham, NC, US; Mancuso, MD; Federico P. Girardi, MD 8Washington University School of Medicine, St. Louis, MO, US; 9UC, Davis School of Medicine, Sacramento, CA, US; 10Norton Hospital for Special Surgery, New York, NY, US Leatherman Spine Center, Louisville, KY, US; 11Scripps Clinic Medical FDA DEVICE/DRUG STATUS: This abstract does not discuss or Group, Department of Orthopedics, La Jolla, CA, US; 12Scripps Clinic, include any applicable devices or drugs. San Diego, CA, US; 13Johns Hopkins University, Baltimore, MD, US; 14 15 University of Calgary, Calgary, Canada; Southwest Scoliosis 196. Reducing bioburden in the operating room: manual Institute, Dallas, TX, US; 16University of Kansas Medical Center, 17 18 cleaning and pulsed-xenon ultraviolet light disinfection Kansas City, KS, US; Denver, CO, US; University of California, San produces significant reduction in colony forming units Francisco, San Francisco, CA, US; 19Swedish Neuroscience Institute, Seattle, WA, US; 20University of Pittsburgh School of Medicine, Ashley Xiong, CCRC Pittsburgh, PA, US; 21Brighton, CO, US Mayo Clinic, Rochester, MN, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. include any applicable devices or drugs.

192. Healthcare resource utilization in lumbar spine 197. In vitro and in vivo assessment of bone regeneration surgery for stenosis: A national claims data analysis after local steroid administration using a rodent Jayme Koltsov, PhD1; Ivan Cheng, MD2; Kirkham B. Wood, MD3; posterolateral fusion model 4 5 Todd F. Alamin, MD ; Serena S. Hu, MD Mark A. Plantz, BS1; Abhishek S. Kannan2; Silvia Minardi, PhD, 1Redwood City, CA, US; 2Stanford University, Redwood City, CA, MS1; David J. Ellenbogen, BA2; Joseph G. Lyons, BS3; Jonathan US; 3Stanford University School of Medicine Dept of Orthopedic Paul, MPH, BS2; Tejas Nandurkar, MS2; Parker Marsh, BS4; Surgery, Redwood City, CA, US; 4Stanford Medicine Outpatient Kennedy Sana5; Eileen Phan, BA2; Allison Wintring, BS6; Elianna Center, Redwood City, CA, US; 5Stanford University School of Fred7; Soyeon Jeong, MS1; Chawon Yun, PhD1; Stuart R. Stock, Medicine, Redwood City, CA, US PhD7; Erin L. Hsu, PhD1; Wellington K. Hsu, MD1 FDA DEVICE/DRUG STATUS: This abstract does not discuss or 1Northwestern University, Chicago, IL, US; 2Chicago, IL, US; include any applicable devices or drugs. 3Northfield, IL, US;4 Simpson Querrey Institute, Chicago , IL, US; 5Northwestern University Simpson Querrey Institute, Chicago, Il, US; 6University of Louisville School of Medicine, Louisville, 193. Biomimetic 3D-printed titanium-alloy interbody KY, US; 7Northwestern University, Feinberg School of Medicine, spacers demonstrate uniform bone growth over 12 weeks Chicago, IL, US 1 1 Margaret R. Van Horn, PhD ; Roland Beard, MS ; Wenhai Wang, FDA DEVICE/DRUG STATUS: rhBMP-2 (INFUSE) [non-human 1 2 3 PhD ; Bryan W. Cunningham, PhD ; Kenneth Mullinix, BS ; Brandon use] (Investigational/Not approved) Bucklen, PhD1 1Globus Medical, Audubon, PA, US; 2MedStar Union Memorial Hospital, Baltimore, MD, US; 3Audubon, PA, US FDA DEVICE/DRUG STATUS: HEDRON (Globus Medical) (Approved for this indication) Abstracts 77

198. Chronic use of hydromorphone and oxycodone 202. Hyperlordotic anterior interbody use without associated with reoperations after lumbar decompression superior articulating process resection has an increased and lumbar interbody fusions risk of Iiatrogenic neurological injury single level circumferential fusion Andre Samuel, MD1; Francis C. Lovecchio, MD1; Ajay Premkumar, MD2; Philip Louie, MD2; Avani S. Vaishnav, MBBS; Han Jo Kim, Kimberly Ashayeri, MD1; Leon Eisen, MD2; Themistocles S. MD1; Steven J. McAnany, MD3; Sravisht Iyer, MD1; Todd J. Albert, Protopsaltis, MD3; Aaron J. Buckland, MBBS, FRACS3 1 1 1 MD ; Catherine Himo Gang, MPH ; Sheeraz A. Qureshi, MD, MBA 1New York, NY, US; 2NYU Langone, NY, NY, US; 3Department of 1Hospital for Special Surgery, New York, NY, US; 2New York, NY, Orthopaedic Surgery, NYU Langone Orthopaedic Hospital, NYU US; 3Hospital for Special Surgery, Stamford, CT, US Langone Health, New York, NY, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. include any applicable devices or drugs.

199. Functional outcome and long-term follow up results 203. The effect of surgical decompression and fusion on after surgery for spinal meningiomas: a population-based functional balance in patients with degenerative lumbar cohort study spondylolisthesis Jenny Pettersson-Segerlind, MD1; Charles Tatter, MD2; Alexander Ram Haddas, PhD, MSc, MEng1; Isador H. Lieberman, MD, Fletcher-Sandersjöö, MD1; Oscar Persson, MD, PhD1; Gustav FRCSC, MBA2; Andrew R. Block, PhD1; Peter B. Derman, MD, MBA1 3 1 1 Burstrom, MD ; Jiri Jr. Bartek, MD ; Petter Förander, MD, PhD ; 1Texas Back Institute, Plano, TX, US; 2Scoliosis and Spine Tumor 4 1 Erik Edström, MD, PhD ; Adrian Elmi Terander, MD, PhD Center, Texas Back Institute, Texas Health Presbyterian Hospital 1Karolinska University Hospital, Stockholm, Sweden; Plano, Plano, TX, US 2 Patientområde Neurokirurgi, Tema Neuro, Karolinska FDA DEVICE/DRUG STATUS: This abstract does not discuss or 3 Universitetssjukhuset, Stockholm, Sweden; Karolinska Institute, include any applicable devices or drugs. Stockholm, Sweden; 4Karolinska University Hospital, Dept Neurosurgery, Solna, Sweden 204. Patient-reported outcomes in patients who stop FDA DEVICE/DRUG STATUS: This abstract does not discuss or following up: are they doing better or worse than the include any applicable devices or drugs. patients that come back? Darren Chen, BA1; Avani S. Vaishnav, MBBS2; Steven J. McAnany, 200. Comparison of freehand, fluoro-guided, CT MD3; Sravisht Iyer, MD3; Todd J. Albert, MD3; Catherine Himo navigation, and robot-guided TLIF and ALIF Gang, MPH3; Sheeraz A. Qureshi, MD, MBA3 1 2 3 Jack Zhong, BA ; Carlos Leon, BS ; Kimberly Ashayeri, MD ; 1New York, NY, US; 2Hospital for Special Surgery, Stamford, CT, 3 4 Eaman Balouch, MD, PhD ; Nicholas O’Malley, BS ; Carolyn US; 3Hospital for Special Surgery, New York, NY, US Stickley, BS5; Constance Maglaras, PhD3; Brooke K. O’Connell, MS3; Aaron J. Buckland, MBBS, FRACS5 FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. 1NYU langone Spine Research Center, New York, NY, US; 2NYU Langone Medical Center, New York City, NY, US; 3New York, NY, US; 4NYU Langone Dept. of Orthopedic Surgery, Division of Spine, 205. The association of U.S. News & World Report hospital New York, NY, US; 5Department of Orthopedic Surgery, NYU ranking and outcomes following anterior cervical fusions: Langone Health, New York, NY, US an analysis of Medicare beneficiaries FDA DEVICE/DRUG STATUS: This abstract does not discuss or Azeem T. Malik, MBBS1; Jack Xie, MS2; Joseph P. Drain, MD1; include any applicable devices or drugs. Elizabeth Yu, MD2; Safdar N. Khan, MD1; Jeffery Kim, MD1 1The Ohio State University Wexner Medical Center, Columbus, 2 201. The necessity and risk factors of subsequent fusion OH, US; Columbus, OH, US after decompression alone for lumbar spinal stenosis with FDA DEVICE/DRUG STATUS: This abstract does not discuss or lumbar spondylolisthesis: 5 years follow-up in two large include any applicable devices or drugs. populations Hikari Urakawa, MD1; Andre Samuel, MD1; Yoshihiro Katsuura, 206. Additional surgery after anterior cervical discectomy MD1; Sravisht Iyer, MD1; Steven J. McAnany, MD2; Todd J. Albert, and fusion vs posterior foraminotomy for single- or MD1; Catherine Himo Gang, MPH1; Sheeraz A. Qureshi, MD, MBA1 multilevel cervical radiculopathy 1 2 Hospital for Special Surgery, New York, NY, US; Hospital for Andre Samuel, MD1; Michael E. Steinhaus, MD1; Philip Louie, Special Surgery, Stamford, CT, US MD2; Hikari Urakawa, MD1; Avani S. Vaishnav, MBBS; Steven J. FDA DEVICE/DRUG STATUS: This abstract does not discuss or McAnany, MD3; Sravisht Iyer, MD1; Todd J. Albert, MD1; Catherine include any applicable devices or drugs. Himo Gang, MPH1; Sheeraz A. Qureshi, MD, MBA1 1Hospital for Special Surgery, New York, NY, US; 2New York, NY, US; 3Hospital for Special Surgery, Stamford, CT, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. Abstracts 78

207. Postmenopausal women presenting for spinal fusion 210. Development of a modified frailty index for adult surgery have abnormal microarchitecture despite normal spinal deformities independent of functional changes DXA following surgical correction: a true baseline risk assessment tool Han Jo Kim, MD1; Matthew E. Cunningham, MD, PhD1; Frank J. Schwab, MD1; Alexander Dash, BA2; Alexandra Krez, BA1; Caroline Peter G. Passias, MD1; Katherine E. Pierce, BS2; Virginie Lafage, Zaworski, BA2; Jonathan Harrison, BA1; Brandon B. Carlson, MD, PhD3; Renaud Lafage, MSc3; Breton Line, BS4; D. Kojo Hamilton, MPH3; Emily M. Stein, MD1 MD5; Juan S. Uribe, MD6; Richard A. Hostin Jr., MD7; Alan H. 8 9 10 1Hospital for Special Surgery, New York, NY, US; 2New York, NY, US; Daniels, MD ; Robert A. Hart, MD ; Douglas C. Burton, MD ; 11 3 3Marc A. Asher Comprehensive Spine Center, Kansas City, KS, US Christopher I. Shaffrey, MD ; Frank J. Schwab, MD ; Christopher P. Ames, MD12; Justin S. Smith, MD, PhD13; Shay Bess, MD14; Eric FDA DEVICE/DRUG STATUS: This abstract does not discuss or O. Klineberg, MD15; International Spine Study Group16 include any applicable devices or drugs. 1NY Spine Institute, NYU Langone Health, New York, NY, US; 2NYU Spine Research Lab, New York, NY, US; 3Hospital for 208. Low pelvic incidence (PI) patients are at high risk of Special Surgery, New York, NY, US; 4Denver International Spine over correction following ASD surgery Center, Denver, CO, US; 5University of Pittsburgh School of Alexandra Soroceanu, MD, MPH1; Themistocles S. Protopsaltis, Medicine, Pittsburgh, PA, US; 6Barrow Neurological Institute, MD2; Gregory M. Mundis Jr., MD3; Justin S. Smith, MD, PhD4; Phoenix, AZ, US; 7Southwest Scoliosis Institute, Dallas, TX, US; Michael P. Kelly, MD; Alan H. Daniels, MD5; Eric O. Klineberg, MD6; 8Warren Alpert Medical School of BU/RI Hospital, Providence, Christopher P. Ames, MD7; Robert A. Hart, MD8; Shay Bess, MD9; RI, US; 9Swedish Neuroscience Institute, Seattle, WA, US; Christopher I. Shaffrey, MD10; Frank J. Schwab, MD11; Virginie 10University of Kansas Medical Center, Kansas City, KS, US; Lafage, PhD11; Munish C. Gupta, MD12; International Spine Study 11Duke University , Durham, NC, US; 12University of California, Group13 San Francisco, San Francisco, CA, US; 13UVA Health System, 14 15 1University of Calgary, Calgary, Canada; 2Department of Charlottesville, VA, US; Denver, CO, US; UC, Davis School of 16 Orthopaedic Surgery, NYU Langone Orthopaedic Hospital, NYU Medicine, Sacramento, CA, US; Brighton, CO, US Langone Health, New York, NY, US; 3Scripps Clinic Medical Group, FDA DEVICE/DRUG STATUS: This abstract does not discuss or Department of Orthopedics, La Jolla, CA, US; 4UVA Health System, include any applicable devices or drugs. Charlottesville, VA, US; 5Warren Alpert Medical School of BU/ RI Hospital, Providence, RI, US; 6UC, Davis School of Medicine, 211. Complications and outcomes in small vs large Sacramento, CA, US; 7University of California, San Francisco, San surgeries for ASD? Francisco, CA, US; 8Swedish Neuroscience Institute, Seattle, WA, US; 9Denver, CO, US; 10Duke University , Durham, NC, US; 11Hospital Themistocles S. Protopsaltis, MD1; Alexandra Soroceanu, for Special Surgery, New York, NY, US; 12Washington University MD, MPH2; Gregory M. Mundis Jr., MD3; Justin S. Smith, MD, School of Medicine, St. Louis, MO, US; 13Brighton, CO, US PhD4; Jeffrey L. Gum, MD5; Alan H. Daniels, MD6; Christopher P. Ames, MD7; Robert A. Hart, MD8; Shay Bess, MD9; Christopher I. FDA DEVICE/DRUG STATUS: This abstract does not discuss or Shaffrey, MD10; Frank J. Schwab, MD11; Virginie Lafage, PhD11; include any applicable devices or drugs. Eric O. Klineberg, MD12; International Spine Study Group13 209. Patient-specific cervical deformity corrections with 1Department of Orthopaedic Surgery, NYU Langone Orthopaedic consideration of associated risk: establishment of risk Hospital, NYU Langone Health, New York, NY, US; 2University benefit thresholds for invasiveness based on deformity of Calgary, Calgary, Canada; 3Scripps Clinic Medical Group, and frailty severity Department of Orthopedics, La Jolla, CA, US; 4UVA Health System, Charlottesville, VA, US; 5Norton Leatherman Spine 1; Katherine E. Pierce, BS2; Renaud Lafage, Peter G. Passias, MD Center, Louisville, KY, US; 6Warren Alpert Medical School of MSc3; Virginie Lafage, PhD3; Eric O. Klineberg, MD4; Alan H. Daniels, BU/RI Hospital, Providence, RI, US; 7University of California, MD5; Khaled M. Kebaish, MD6; Themistocles S. Protopsaltis, MD7; San Francisco, San Francisco, CA, US; 8Swedish Neuroscience Richard A. Hostin Jr., MD8; Breton Line, BS9; Robert A. Hart, MD10; Institute, Seattle, WA, US; 9Denver, CO, US; 10Duke University Douglas C. Burton, MD11; Shay Bess, MD12; Frank J. Schwab, , Durham, NC, US; 11Hospital for Special Surgery, New York, MD3; Christopher I. Shaffrey, MD13; Justin S. Smith, MD, PhD14; NY, US; 12UC, Davis School of Medicine, Sacramento, CA, US; Christopher P. Ames, MD15; International Spine Study Group16 13Brighton, CO, US 1NY Spine Institute, NYU Langone Health, New York, NY, US; 2NYU FDA DEVICE/DRUG STATUS: This abstract does not discuss or Spine Research Lab, New York, NY, US; 3Hospital for Special include any applicable devices or drugs. Surgery, New York, NY, US; 4UC, Davis School of Medicine, Sacramento, CA, US; 5Warren Alpert Medical School of BU/RI Hospital, Providence, RI, US; 6Johns Hopkins University, Baltimore, MD, US; 7Department of Orthopaedic Surgery, NYU Langone Orthopaedic Hospital, NYU Langone Health, New York, NY, US; 8Southwest Scoliosis Institute, Dallas, TX, US; 9Denver International Spine Center, Denver, CO, US; 10Swedish Neuroscience Institute, Seattle, WA, US; 11University of Kansas Medical Center, Kansas City, KS, US; 12Denver, CO, US; 13Duke University, Durham, NC, US; 14UVA Health System, Charlottesville, VA, US; 15University of California, San Francisco, San Francisco, CA, US; 16Brighton, CO, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. Abstracts 79

212. Operative treatment of adult spinal deformity 215. Outcomes with transforaminal endoscopic vs patients with severe scoliosis: retrospective review of a percutaneous laser decompression for contained lumbar prospectively collected multicenter series with minimum herniated disc: A survival analysis of treatment benefit 2-year follow up Kai-Uwe Lewandrowski, MD1; Paulo T. De Carvalho, MD, PhD2; Thomas Buell, MD1; Justin S. Smith, MD, PhD2; Christopher Anthony T. Yeung, MD3 3 4 5 I. Shaffrey, MD ; Han Jo Kim, MD ; Eric O. Klineberg, MD ; 1Center For Advanced Spinal Surgery, Tucson, AZ, US; 2UNIRIO, 4 4 Virginie Lafage, PhD ; Renaud Lafage, MSc ; Themistocles S. Rio de Janeiro, RJ, Brazil; 3Desert Institute for Spine Care, 6 7 Protopsaltis, MD ; Peter G. Passias, MD ; Gregory M. Mundis Jr., Phoenix, AZ, US MD8; Robert K. Eastlack, MD9; Vedat Deviren, MD10; Michael P. Kelly, MD; Alan H. Daniels, MD11; Jeffrey L. Gum, MD12; Alexandra FDA DEVICE/DRUG STATUS: This abstract does not discuss or Soroceanu, MD, MPH13; D. Kojo Hamilton, MD14; Munish C. Gupta, include any applicable devices or drugs. MD15; Douglas C. Burton, MD16; Richard A. Hostin Jr., MD17; Khaled M. Kebaish, MD18; Robert A. Hart, MD19; Frank J. Schwab, MD4; 216. Contrary to popular belief, self-image in adult Shay Bess, MD20; Christopher P. Ames, MD10; International Spine spinal deformity (ASD) is most correlated with physical Study Group21 and social function and mental health and minimally 1University of Virginia Neurosurgery, Charlottesville, VA, US; 2UVA correlated with magnitude of spine deformity 3 Health System, Charlottesville, VA, US; Duke University, Durham, Raymarla Pinteric1; Shay Bess, MD2; Breton Line, BS3; Michael 4 5 NC, US; Hospital for Special Surgery, New York, NY, US; UC, P. Kelly, MD; Christopher P. Ames, MD4; Gregory M. Mundis Jr., 6 Davis School of Medicine, Sacramento, CA, US; Department MD5; Robert K. Eastlack, MD6; Richard A. Hostin Jr., MD7; Eric O. of Orthopaedic Surgery, NYU Langone Orthopaedic Hospital, Klineberg, MD8; Munish C. Gupta, MD9; Khaled M. Kebaish, MD10; 7 NYU Langone Health, New York, NY, US; NY Spine Institute, Virginie Lafage, PhD11; Renaud Lafage, MSc12; Douglas C. Burton, 8 NYU Langone Health, New York, NY, US; Scripps Clinic Medical MD13; Frank J. Schwab, MD12; Christopher I. Shaffrey, MD14; Justin 9 Group, Department of Orthopedics, La Jolla, CA, US; Scripps S. Smith, MD, PhD15; International Spine Study Group1 10 Clinic, San Diego, CA, US; University of California, San Francisco, 1 2 3 11 Brighton, CO, US; Denver, CO, US; Denver International San Francisco, CA, US; Warren Alpert Medical School of BU/RI 4 12 Spine Center, Denver, CO, US; University of California, San Hospital, Providence, RI, US; Norton Leatherman Spine Center, 6 13 Francisco, San Francisco, CA, US; Scripps Clinic Medical Group, Louisville, KY, US; University of Calgary, Calgary, Canada; 7 14 Department of Orthopedics, La Jolla, CA, US; Scripps Clinic, San University of Pittsburgh School of Medicine, Pittsburgh, PA, 8 9 15 Diego, CA, US; Southwest Scoliosis Institute, Dallas, TX, US; UC, US; Washington University School of Medicine, St. Louis, MO, 10 16 Davis School of Medicine, Sacramento, CA, US; Washington US; University of Kansas Medical Center, Kansas City, KS, US; 11 17 18 University School of Medicine, St. Louis, MO, US; Johns Hopkins Southwest Scoliosis Institute, Dallas, TX, US; Johns Hopkins 12 19 University, Baltimore, MD, US; Hospital for Special Surgery, New University, Baltimore, MD, US; Swedish Neuroscience Institute, 13 Seattle, WA, US; 20Denver, CO, US; 21Brighton, CO, US York, NY, US; University of Kansas Medical Center, Kansas City, KS, US; 14Duke University , Durham, NC, US; 15UVA Health System, FDA DEVICE/DRUG STATUS: This abstract does not discuss or Charlottesville, VA, US include any applicable devices or drugs. FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. 213. Study comparing NTG-101, a growth factor-based therapy with mesenchymal stem cell (MSC) based treatment of degenerative disc disease (DDD) in pre- 217. Outcomes of surgical treatment for patients with clinical rodent model mild scoliosis and age appropriate sagittal alignment with minimum 2-year follow up 1 1 Ajay Matta, PhD ; Muhammad Zia Karim, DVM ; Hoda Gerami, 1 2 BS1; Bettina Zoe Benigno, BS1; William Mark Erwin, DC, PhD2 Justin K. Scheer, MD ; Justin S. Smith, MD, PhD ; Peter G. Passias, MD3; Han Jo Kim, MD4; Shay Bess, MD5; Themistocles 1 2 Notogen, Toronto, ON, Canada; Dept of Surgery, Univ of Toronto, S. Protopsaltis, MD6; Douglas C. Burton, MD7; Eric O. Klineberg, Toronto, ON, Canada MD8; Virginie Lafage, PhD4; Frank J. Schwab, MD4; Christopher I. FDA DEVICE/DRUG STATUS: This abstract does not discuss or Shaffrey, MD9; Munish C. Gupta, MD10; Christopher P. Ames, MD1; include any applicable devices or drugs. International Spine Study Group11 1University of California, San Francisco, San Francisco, CA, US; 2 3 214. Viable allograft supplement for disc degeneration: UVA Health System, Charlottesville, VA, US; NY Spine Institute, 4 measurable disc height increases at 12 months in first 24 NYU Langone Health, New York, NY, US; Hospital for Special 5 6 subjects Surgery, New York, NY, US; Denver, CO, US; Department of Orthopaedic Surgery, NYU Langone Orthopaedic Hospital,

Douglas P. Beall, MD NYU Langone Health, New York, NY, US; 7University of Kansas Clinical Radiology of Oklahoma, Edmond, OK, US Medical Center, Kansas City, KS, US; 8UC, Davis School of 9 FDA DEVICE/DRUG STATUS: This abstract does not discuss or Medicine, Sacramento, CA, US; Duke University, Durham, NC, US; 10 include any applicable devices or drugs. Washington University School of Medicine, St. Louis, MO, US; 11Brighton, CO, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. Abstracts 80

218. Preoperative opioid use is associated with increased 222. Metabolic bone mineralization disorders (MBD) readmission and reoperation rates following lumbar increase 2-year adverse outcome following lumbar short decompression, instrumentation and fusion fusion for degenerative lumbar disease Alex Mierke, MD1; Jun Ho Chung2; Wayne K. Cheng, MD3; Bassel G. Diebo, MD1; George A. Beyer, MS2; Neil V. Shah, MD, Olumide A. Danisa, MD2 MS1; Hallie Tiburzi, BA3; Adam J. Wolfert, BA2; Salem Najjar, BA4; 5 6 1Loma Linda University, Loma Linda, CA, US; 2Loma Linda Renaud Lafage, MSc ; Frank A. Segreto, BS ; Peter G. Passias, 7 5 5 University School of Medicine, Loma Linda, CA, US; 3Bones and MD ; Frank J. Schwab, MD ; Virginie Lafage, PhD ; Carl B. Paulino, 2 Spine Surgery, Loma Linda, CA, US MD 1 FDA DEVICE/DRUG STATUS: This abstract does not discuss or Department of Orthopaedic Surgery, SUNY Downstate Medical 2 include any applicable devices or drugs. Center, Brooklyn, NY, US; SUNY Downstate Medical Center, Brooklyn, NY, US; 3Staten Island University Hospital, Staten Island, NY, US; 4Zucker School of Medicine at Hofstra/Northwell, 219. Transforaminal lumbar interbody fusion may prevent Hempstead, NY, US; 5Hospital for Special Surgery, New York, early postoperative pedicle screw loosening NY, US; 6NYU Langone Medical Center - Orthopaedic Hospital, 7 David H. Kim, MD1; Raymond Hwang, MD, MS, MBA2; Gyu Ho Lee, Manhattan, NY, US; NY Spine Institute, NYU Langone Health, MA3; Riya Joshi, MBBS, MPH4; Kevin Baker, PhD5; Paul M. Arnold, New York, NY, US MD6; Rick C. Sasso, MD7; Daniel K. Park, MD8; Jeffrey Fischgrund, FDA DEVICE/DRUG STATUS: This abstract does not discuss or MD9 include any applicable devices or drugs. 1Tufts University Medical Group, NEBH, Boston, MA, US; 2New England Baptist Hospital, New England Orthopedic and Spine 223. Development and validation of a novel scoring tool 3 Surgery, Chestnut Hill, MA, US; Icahn School of Medicine at for predicting facility discharge after elective posterior 4 Mount Sinai, New York, NY, US; Cytel, Cambridge, MA, US; lumbar fusion 5Beaumont Health, Royal Oak, MI, US; 6Carle Foundation Hospital, 1 2 Urbana, IL, US; 7Indiana Spine Group, Carmel, IN, US; 8Southfield, Garrett Harada, MD ; Bryce Basques, MD, MHS ; Dino Samartzis, 3 4 4 MI, US; 9Franklin, MI, US ScD, PhD, MSc ; Edward J. Goldberg, MD ; Matthew Colman, MD ; Howard S. An, MD5 FDA DEVICE/DRUG STATUS: This abstract does not discuss or 1 2 include any applicable devices or drugs. Los Angeles, CA, US; Thomas Jefferson University, Philadelphia, PA, US; 3Queen Mary Hospital, Hong Kong, Hong Kong; 4Midwest Orthopedics at Rush, Chicago, IL, US; 5Rush University Medical 220. The cross-sectional area of psoas muscle impacts Center, Department of Orthopedic Surgery, Chicago, IL, US functional outcomes of MI-TLIF for lumbar degenerative FDA DEVICE/DRUG STATUS: This abstract does not discuss or diseases include any applicable devices or drugs. Hikari Urakawa, MD1; Kosuke Sato, MD2; Avani S. Vaishnav, MBBS1; Ryan Lee, MBA1; Chirag Chaudhary, MS, MBBS1; Yoshihiro Katsuura, MD1; Steven J. McAnany, MD3; Sravisht Iyer, MD1; Todd 224. The utility of neuromonitoring in cervical myelopathy J. Albert, MD1; Catherine Himo Gang, MPH1; Sheeraz A. Qureshi, patients MD, MBA1 Jason Bryman, MD1; Kristen Combs, MD2; Robert Kay, MD1; 3 2 4 1Hospital for Special Surgery, New York, NY, US; 2New York, NY, Adam Taylor, MD ; Erik Tye, MD ; Kevin W. Rolfe, MD, MPH US; 3Hospital for Special Surgery, Stamford, CT, US 1Harbor UCLA Medical Center, Torrance, CA, US; 2Torrance, CA, 3 FDA DEVICE/DRUG STATUS: This abstract does not discuss or US; Harbor UCLA Medical Center, Redondo Beach, CA, US; 4 include any applicable devices or drugs. Downey, CA, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. 221. Change in sagittal alignment after decompression alone in patients with lumbar spinal stenosis: a prospective cohort study 225. Severity of cervical disc degeneration and health- related quality of life outcomes following anterior cervical Jamal Bech Bouknaitir, MD1; Leah Y. Carreon, MD, MSc2; Stig Brorson, MD, PhD3; Mikkel Andersen, MD4 discectomy and fusion 1 2 1Zealand University Hospital, Koege, Denmark; 2Sygehus Lillebælt Parthik Patel, MD ; Jose A. Canseco, MD, PhD ; Michael 3 4 4 - Rygkirurgi Middelfart, Middelfart, Middelfart, Denmark; 3Zealand Markowitz, DO ; Daniel Campbell, BS ; Lauren Thaete ; Joseph 5 6 5 University Hospital, Dept. of Orthopaedic Surgery, Koege, K. Lee, MD ; Mark F. Kurd, MD ; D. Greg Anderson, MD ; Alan S. 5 5 Denmark; 4Middelfart, Denmark Hilibrand, MD ; Christopher K. Kepler, MD, MBA ; Alexander R. Vaccaro, MD, PhD5; Gregory D. Schroeder, MD7 FDA DEVICE/DRUG STATUS: This abstract does not discuss or 1 2 include any applicable devices or drugs. Philadelphia, PA, US; Rothman Institute/Thomas Jefferson University Hospital, Philadelphia, PA, US; 3Haddon, NJ, US; 4Sidney Kimmel Medical College, Philadelphia, PA, US; 5Rothman Institute, Philadelphia, PA, US; 6Rothman Institute, Bryn Mawr, PA, US; 7Rothman Institute Thomas Jefferson University, Philadelphia, PA, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. Abstracts 81

226. Sequential correction of the severe and rigid 231. The use of fusion mass screws in revision spinal thoracic kyphoscoliosis: a new technical note and deformity surgery: preliminary results and analysis preliminary results Ashish Mittal, MD1; Alexander Rosinski, MS1; Khalid Odeh, MD1; Cao Yang, MD Victor Ungurean, MD2; Dimitriy G. Kondrashov, MD3 Wuhan, China 1San Francisco, CA, US; 2Chisinau, Moldova; 3San Francisco Spine FDA DEVICE/DRUG STATUS: This abstract does not discuss or Surgeons, San Francisco, CA, US include any applicable devices or drugs. FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. 227. Is the axial spinal cord classification predictive of intraoperative neurologic alert for pediatric scoliosis 232. Optimal lumbar lordosis correction for adult spinal patients? A validation study deformity with severe sagittal imbalance in patients over age 65: role of pelvic tilt and pelvic tilt ratio Smitha Mathew, MD; Todd Milbrandt; William J. Shaughnessy, MD; Anthony A. Stans, MD; Annalise N. Larson, MD Jung-Hee Lee, MD, PhD1; Ki Young Lee, MD2; Sang Kyu Im, MD3; 1 4 1 Mayo Clinic, Rochester, MN, US Haeseong Lim, PhD ; Jinsoo Kim, MD ; Taesu Jang, MD ; Seong Jin Cho, MD1 FDA DEVICE/DRUG STATUS: This abstract does not discuss or 1 include any applicable devices or drugs. Kyunghee University Medical Center, Seoul, Republic of Korea; 2Department of Orthopedic Surgery, Graduate School, College of Medicine, Kyung Hee University, Seoul, South Korea; 3Seoul, 228. A predictive model of perioperative myocardial South Korea; 4Seoul Medical Center, Seoul, Republic of Korea infarction in spine surgery FDA DEVICE/DRUG STATUS: This abstract does not discuss or Peter G. Passias, MD1; Katherine E. Pierce, BS2; Sara Naessig, include any applicable devices or drugs. BS3; Waleed Ahmad4; Cheongeun Oh, PhD5; Erik Wang, BA6; Bassel G. Diebo, MD7 233. Development of risk stratification predictive models 1 2 NY Spine Institute, NYU Langone Health, New York, NY, US; NYU for cervical deformity surgery Spine Research Lab, New York, NY, US; 3NYU Langone Hospital, 1 2 3 New York NY, US; 4New York, NY, US; 5NYU Medical Center, New Peter G. Passias, MD ; Waleed Ahmad ; Cheongeun Oh, PhD ; 4 4 York, NY, US; 6Department of Orthopedic Surgery, NYU Langone Virginie Lafage, PhD ; Renaud Lafage, MSc ; D. Kojo Hamilton, 5 6 7 Orthopedic Hospital, NYU Langone Health, New York, NY, US; MD ; Themistocles S. Protopsaltis, MD ; Eric O. Klineberg, MD ; 8 9 10 7Department of Orthopaedic Surgery, SUNY Downstate Medical Jeffrey L. Gum, MD ; Breton Line, BS ; Robert A. Hart, MD ; 11 12 Center, Brooklyn, NY, US Douglas C. Burton, MD ; Shay Bess, MD ; Frank J. Schwab, MD4; Christopher I. Shaffrey, MD13; Justin S. Smith, MD, PhD14; FDA DEVICE/DRUG STATUS: This abstract does not discuss or Christopher P. Ames, MD15; International Spine Study Group16 include any applicable devices or drugs. 1NY Spine Institute, NYU Langone Health, New York, NY, US; 2New York, NY, US; 3NYU Medical Center, New York, NY, US; 229. Comparative analysis of 30-day readmission, 4Hospital for Special Surgery, New York, NY, US; 5University of reoperation, and morbidity between lumbar disc Pittsburgh School of Medicine, Pittsburgh, PA, US; 6Department arthroplasty performed in the inpatient and outpatient of Orthopaedic Surgery, NYU Langone Orthopaedic Hospital, settings utilizing the 2005-2018 ACS-NSQIP datasets NYU Langone Health, New York, NY, US; 7UC, Davis School 8 Austen Katz, MD; Dean C. Perfetti, MD, MPH; Alan Job, MD; of Medicine, Sacramento, CA, US; Norton Leatherman Spine 9 Michael Fitzgerald, MD; Jeffrey A. Goldstein, MD; Daniel Kiridly, Center, Louisville, KY, US; Denver International Spine Center, 10 MD, MBA; Alexander M. Satin, MD; David A. Essig, MD Denver, CO, US; Swedish Neuroscience Institute, Seattle, WA, US; 11University of Kansas Medical Center, Kansas City, KS, US; Northwell Health Orthopedics, Long Island Jewish Medical 12Denver, CO, US; 13Duke University, Durham, NC, US; 14UVA Health Center, Queens, NY, US System, Charlottesville, VA, US; 15University of California, San FDA DEVICE/DRUG STATUS: This abstract does not discuss or Francisco, San Francisco, CA, US; 16Brighton, CO, US include any applicable devices or drugs. FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. 230. Racial and ethnic variation in sagittal spinopelvic parameters in an urban setting 234. Cost-effectiveness analysis of teriparatide therapy Woojin Cho, MD, PhD1; Sandip Tarpada, BA1; Dongyoung Kim, for the prevention of proximal junctional kyphosis/failure BS2; Brittany A. Oster, BS2; Hyun Jin Lim, BA1 and subsequent revision after adult spinal deformity 1Bronx, NY, US; 2Englewood Cliffs, NJ, US surgery FDA DEVICE/DRUG STATUS: This abstract does not discuss or Ichiro Okano, MD; Jingyan Yang, PhD; Stephan Salzmann, MD; include any applicable devices or drugs. Jennifer Shue, MS; Andrew A. Sama, MD; Frank P. Cammisa, MD; Federico P. Girardi, MD; Alexander P. Hughes, MD Hospital for Special Surgery, New York, NY, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. Abstracts 82

235. Evaluation of a nanosynthetic silicated calcium 239. Comparison of single-position robot-assisted phosphate putty in a posterolateral rabbit spinal fusion surgery vs conventional minimally invasive surgery model following LLIF: an in vitro assessment William Walsh, PhD1; Rema Oliver, PhD2; Tian Wang, PhD3; Daniel Themistocles S. Protopsaltis, MD1; Jeffrey J. Larson, MD2; Wills, DVM4; Jordan Conway5; Thomas Buckland, PhD6; Iain R. Richard F. Frisch Jr., MD3; Kade T. Huntsman, MD4; Todd J. Gibson, PhD7 Lansford, MD5; Robert L. Brady, MD6; Chris Maulucci, MD, 7 8 8 8 1Surgical and Orthopaedic Research Labs, Randwick, FACS ; Gerald Hayward, BS ; Jonathan Harris ; Jorge Gonzalez ; 8 Maroubra, Australia; 2Surgical & Orthopaedic Research Lab- Brandon Bucklen, PhD UNSW, Randwick, Australia; 3Surgical & Orthopaedic Research 1Department of Orthopaedic Surgery, NYU Langone Orthopaedic Laboratories (SORL), Sydney, Australia; 4Surgical and Orthopaedic Hospital, NYU Langone Health, New York, NY, US; 2Coeur D’Alene Research Laboratories, Level 1 Clinical Sci Bldg, Randwick, NSW, Spine & Brain, PLLC, Coeur D Alene, ID, US; 3Southeastern Spine Australia; 5SIRAKOSS Limited, Aberdeen, Scotland; 6Perspective Institute, Mt Pleasant, SC, US; 4Salt Lake Orthopaedic Clinic, Device Consulting, Didcot, United Kingdom; 7University of Salt Lake City, UT, US; 5South Carolina Sports Medicine, North Aberdeen, Aberdeen, IN, United Kingdom Charleston, SC, US; 6Coastal Orthopaedics, P.C., Norwalk, CT, 7 FDA DEVICE/DRUG STATUS: Osteo 3 (the Nanosynthetic US; Tulane University School of Medicine, New Orleans, LA, US; 8 Silicated CaP Putty ) (Investigational/Not approved) Globus Medical, Inc., Audubon, PA, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. 236. Ectopic bone formation by submicron structured calcium phosphates: role of the innate immune system 240. A subtractive biomimetic titanium surface promotes Huipin Yuan, PhD1; Lukas A. van Dijk, MSc2; Joost DeBruijn, PhD3 bony ongrowth in an ovine lumbar interbody fusion model 1Bilthoven, Netherlands; 2University Medical Centre Utrecht, 1 1 Utrecht, Netherlands; 3Kuros Biosciences, Bilthoven, Netherlands Margaret R. Van Horn, PhD ; Roland Beard, MS ; Bryan W. Cunningham, PhD2; Kenneth Mullinix, BS3; May Allall1 FDA DEVICE/DRUG STATUS: MagnetOs Granules (Not approved 1 2 for this indication) Globus Medical, Audubon, PA, US; MedStar Union Memorial Hospital, Baltimore, MD, US; 3Audubon, PA, US FDA DEVICE/DRUG STATUS: SINTROS (Globus Medical) 237. Individual plates vs single plate for multi-level (Approved for this indication) fixation results in superior biomechanics in anterior cervical fusion surgery 241. Pre-clinical safety and performance assessment of Ali Kiapour, PhD1; Elie Massaad, MD1; John H. Shin, MD2 a novel 3D-printed HA-DBM composite scaffold using a 1 2 Boston, MA, US; Massachusetts General Hospital, Boston, MA, rodent posterolateral fusion model US Mark A. Plantz, BS1; Joseph G. Lyons, BS2; Jonathan Paul, MPH, FDA DEVICE/DRUG STATUS: This abstract does not discuss or BS3; Tejas Nandurkar, MS3; Parker Marsh, BS4; James Foley, MD3; include any applicable devices or drugs. Alison Wintring, BS5; Eileen Phan, BA3; Elianna Fred6; Soyeon Jeong, MS1; Chawon Yun, PhD1; Silvia Minardi, PhD, MS1; Ramille 238. Interbody spacers and instability: is there a N. Shah, PhD3; Adam E. Jakus, PhD7; Kenneth R. Blank, PhD, MS, difference in subsidence and range of motion between MHA8; Robert M. Havey, MS9; Muturi Muriuki, PhD10; Avinash various cages for osteotomy techniques? G. Patwardhan, PhD11; Stuart R. Stock, PhD6; Erin L. Hsu, PhD1; Wellington K. Hsu, MD1 Basem Ishak, MD; Alexander Von Glinski, MD1; Clifford Pierre, 1 2 MD1; Jonathan M. Mahoney, BS2; Jonathan Harris2; Evan Thai2; Northwestern University, Chicago, IL, US; Northfield, IL, US; 3 4 May Allall2; Brandon Bucklen, PhD2; Rod J. Oskouian Jr., MD3; Chicago, IL, US; Simpson Querrey Institute, Chicago, IL, US; 5 Jens R. Chapman, MD4 University of Louisville School of Medicine, Louisville, KY, US; 6 1 2 Northwestern University, Feinberg School of Medicine, Chicago, Swedish Medical Center, Seattle, WA, US; Globus Medical, 7 8 3 IL, US; Dimension Inx LLC, Chicago, IL, US; Tinley Park, IL, US; Audubon, PA, US; Swedish Neuroscience Specialists, Seattle, WA, 9 10 4 Edward Hines Jr. VA Hospital, Hines, IL, US; Forest Park, IL, US; US; Swedish Neuroscience Institute, Seattle, WA, US 11Loyola University Medical Center Dept. of Orthopaedic Surgery, FDA DEVICE/DRUG STATUS: RISE (Globus Medical Inc.) (Not Wheaton, IL, US approved for this indication), SUSTAIN (Globus Medical Inc.) (Not FDA DEVICE/DRUG STATUS: rhBMP-2 (INFUSE) [non-human use] approved for this indication), SIGNATURE (Globus Medical Inc.) (Investigational/Not approved) (Not approved for this indication) Abstracts 83

242. A national analysis on complications and 246. Medical optimization after orthopedic spine and total readmissions for adult cerebral palsy patients undergoing joint arthroplasty decreases readmission primary spinal fusion surgery Megan Mooney, MD; Emily I. Wynkoop, MD; Anthony D. Kouri, Nathan J. Lee, MD1; Michael Fields, BS2; Kyle L. McCormick, BA2; MD; Mina B. Tanios, MD; Hossein K. Elgafy, MD, FRCSC, MBA 2 3 2 Venkat Boddapati, MD ; Meghan Cerpa, MPH ; Jun S. Kim, MD ; University of Toledo Medical Center, Department of Orthopaedic 2 4 Paul Park, MD ; Zeeshan Sardar, MD, MSc ; Ronald A. Lehman Jr, Surgery, Toledo, OH, US MD5; Lawrence G. Lenke, MD6 FDA DEVICE/DRUG STATUS: This abstract does not discuss or 1 2 Columbia University, New York, NY, US; New York, NY, US include any applicable devices or drugs. 3Columbia University Medical Center, New York, NY, US; 4NewYork-Presbyterian The Allen Hospital, New York, NY, US; 5The Spine Hospital -Columbia University/New York Presbyterian, 247. Management of grade IV pressure ulcer with a novel New York, NY, US; 6Columbia University Department of negative pressure device in traumatic paraplegia subjects Orthopedic Surgery, New York, NY, US Rajeshwar N. Srivastava, MD1; Mukesh K. Dwivedi, PhD, PhD2; FDA DEVICE/DRUG STATUS: This abstract does not discuss or Amit K. Bhagat, PhD3; Saloni Raj, MPH3; Lavini Raj, BS3 include any applicable devices or drugs. 1King George’s Medical University, Dept of Ortho Surgery, Lucknow, India; 2Department of Orthopaedic Surgery, Lucknow, 3 243. Predictors of inpatient admission in the setting of India; Department of Orthopaedic Surgery King George’s Medical anterior lumbar interbody fusion University, Lucknow, Uttar Pradesh, India Nathaniel Jenkins, BS, MS1; James Parrish, MPH1; Nadia FDA DEVICE/DRUG STATUS: This abstract does not discuss or Hrynewycz, BS2; Thomas Brundage, BS3; Minimally Invasive Spine include any applicable devices or drugs. Study Group2; Kern Singh, MD1 1Rush University Medical Center, Chicago, IL, US; 2Chicago, IL, US; 248. Hepatitis C virus infection as a predictor of 3Midwest Orthopedics at Rush, Chicago, IL, US complications and increased costs following primary lumbar fusion surgery FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. Chester J. Donnally III, MD1; Parthik D. Patel, MD1; Jose A. Canseco, MD, PhD2; Kartik Shenoy, MD3; Srikanth Divi, MD1; Vadim Goz, MD4; Abdul Arain, MD, MSc5; Alexander R. Vaccaro, MD, PhD4 244. Relationship between 25-hydroxy vitamin D level and 1 2 surgical site infection in spine surgery Philadelphia, PA, US; Rothman Institute/Thomas Jefferson University Hospital, Philadelphia, PA, US; 3Department of 1 2 3 Serena E. Liu, MD, MSc ; Aron Sulovari, BA ; Peter Joo, BA ; Orthopedic Surgery, NYU Langone Orthopedic Hopsital, 1 4 Caroline P. Thirukumaran, MBBS, MHA, PhD ; Addisu Mesfin, MD NYU Langone Health, New York, NY, US; 4Rothman Institute, 1University of Rochester Medical Center, Rochester, NY, US; Philadelphia, PA, US; 5Albany Medical Center, Albany, NY, US 2 University of Rochester School of Medicine and Dentistry, FDA DEVICE/DRUG STATUS: This abstract does not discuss or 3 4 Rochester, NY, US; Rochester, NY, US; University of Rochester, include any applicable devices or drugs. Rochester, NY, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or 249. A novel posterior total joint replacement for the include any applicable devices or drugs. lumbar spine as an alternative to fusion: pilot data for the first 84 patients 245. Predicting massive intraoperative blood loss in adult John A. Sielatycki, MD1; Steven C. Humphreys, MD2; Marissa spinal deformity surgery Koscielski, MS3; Tyler Metcalf, BS3; Jacquelyn S. Pennings, PhD4; Alexandra Soroceanu, MD, MPH1; Justin K. Scheer, MD2; Robert N. Dunn, MD5; Clinton J. Devin, MD4; Scott D. Hodges, DO1 3 4 Themistocles S. Protopsaltis, MD ; Munish C. Gupta, MD ; 1Center for Sports Medicine and Orthopaedics, Chattanooga, 5 6 Peter G. Passias, MD ; Jeffrey L. Gum, MD ; Justin S. Smith, TN, US; 2Kenai Spine, Soldotna, AK, US; 3Columbus, OH, US; 7 8 9 MD, PhD ; Gregory M. Mundis Jr., MD ; Shay Bess, MD ; Virginie 4Vanderbilt University Medical Center, Nashville, TN, US; 5Cape 10 2 11 Lafage, PhD ; Christopher P. Ames, MD ; Eric O. Klineberg, MD ; Town, Western Cape, South Africa International Spine Study Group12 FDA DEVICE/DRUG STATUS: 3Spine BalancedBack Lumbar Joint 1 2 University of Calgary, Calgary, Canada; University of California, Replacement (Investigational/Not approved) San Francisco, San Francisco, CA, US; 3Department of Orthopaedic Surgery, NYU Langone Orthopaedic Hospital, NYU Langone Health, New York, NY, US; 4Washington University School of Medicine, St. Louis, MO, US; 5NY Spine Institute, NYU Langone Health, New York, NY, US; 6Norton Leatherman Spine Center, Louisville, KY, US; 7UVA Health System, Charlottesville, VA, US; 8Scripps Clinic Medical Group, Department of Orthopedics, La Jolla, CA, US; 9Denver, CO, US; 10Hospital for Special Surgery, New York, NY, US; 11UC, Davis School of Medicine, Sacramento, CA, US; 12Brighton, CO, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. Abstracts 84

250. Occurrence and clinical implications of heterotopic 255. Minimally-invasive percutaneous treatments for ossification after cervical disc arthroplasty with Prestige low back pain: a randomized controlled study of thermal LPTM disc at two contiguous levels disc decompression vs mechanical percutaneous disc decompression Matthew F. Gornet, MD1; Todd H. Lanman, MD2; J. Kenneth Burkus, MD3; Randall F. Dryer, MD4; Jeffrey R. McConnell, MD5; Fabrizio Vecchietti, MD1; Edoardo Maria Pandolfi, MD2; Fabrizio Scott D. Hodges, DO6; Francine W. Schranck, RN, BSN7; Guorong Fasoli, MD3 8 Ma, PhD 1Ospedale CTO Roma, Roma, Italy; 2C.T.O Alesini, Roma, Italy; 1The Orthopedic Center of St. Louis, St. Louis, MO, US; 2Beverly 3CTO, Roma, Italy 3 Hills, CA, US; The Hughston Clinic, PC, Columbus, GA, US; FDA DEVICE/DRUG STATUS: This abstract does not discuss or 4 5 Central Texas Spine Institute, Austin, TX, US; LVPG Orthopedics include any applicable devices or drugs. and Sports Medicine, Allentown, PA, US; 6Center for Sports Medicine & Orthopaedics, Chattanooga, TN, US; 7SPIRITT Research, Saint Louis, MO, US; 8Medtronic Spinal and Biologics, 256. Does patient frailty status influence recovery Minneapolis, MN, US patterns and ultimate outcome following spinal fusion for cervical deformity? FDA DEVICE/DRUG STATUS: Prestige LPTM Disc, Approved for 2-level cervical disc arthroplasty in 2016 (Approved for this Katherine E. Pierce, BS1; Peter G. Passias, MD2; Virginie Lafage, indication) PhD3; Renaud Lafage, MSc3; Themistocles S. Protopsaltis, MD4; Han Jo Kim, MD3; Robert K. Eastlack, MD5; Alan H. Daniels, MD6; D. Kojo Hamilton, MD7; Alexandra Soroceanu, MD, MPH8; Robert 251. Location of the fused level does not affect the A. Hart, MD9; Douglas C. Burton, MD10; Shay Bess, MD11; Frank J. behavior of disc replacement adjacent to fusion in hybrid Schwab, MD3; Christopher I. Shaffrey, MD12; Justin S. Smith, MD, surgery PhD13; Christopher P. Ames, MD14; International Spine Tingkui Wu, MD Study Group15 West China Hospital, Sichuan University, Chengdu, Sichuan, 1NYU Spine Research Lab, New York, NY, US; 2NY Spine Institute, China NYU Langone Health, New York, NY, US; 3Hospital for Special 4 FDA DEVICE/DRUG STATUS: This abstract does not discuss or Surgery, New York, NY, US; Department of Orthopaedic Surgery, include any applicable devices or drugs. NYU Langone Orthopaedic Hospital, NYU Langone Health, New York, NY, US; 5Scripps Clinic, San Diego, CA, US; 6Warren Alpert Medical School of BU/RI Hospital, Providence, RI, US; 7University 252. Kinematic response of cervical disc arthroplasty in of Pittsburgh School of Medicine, Pittsburgh, PA, US; 8University of different hybrid constructs Calgary, Calgary, Canada; 9Swedish Neuroscience Institute, Seattle, 10 Jehad Zakaria, MD1; Muturi Muriuki, PhD2; Robert M. Havey, MS3; WA, US; University of Kansas Medical Center, Kansas City, KS, 11 12 13 Suguna Pappu, MD, PhD4; Kenneth R. Blank, PhD, MS, MHA5; US; Denver, CO, US; Duke University , Durham, NC, US; UVA 14 Avinash G. Patwardhan, PhD6 Health System, Charlottesville, VA, US; University of California, San Francisco, San Francisco, CA, US; 15Brighton, CO, US 1Maywood, IL, US; 2Forest Park, IL, US; 3Edward Hines Jr. VA Hospital, Hines, IL, US; 4Department of Neurological Surgery, FDA DEVICE/DRUG STATUS: This abstract does not discuss or Maywood, IL, US; 5Tinley Park, IL, US; 6Loyola University Medical include any applicable devices or drugs. Center Dept. of Orthopaedic Surgery, Wheaton, IL, US FDA DEVICE/DRUG STATUS: M6C artificial cervical disc, Orthofix, 257. Persistent opioid use and resource utilization in Inc (Not approved for this indication) spine surgery Kibum Kim, PhD1; Jennifer Babin, PharmD1; Joseph E. Biskupiak, 253. Long term outcome following percutaneous image- PhD1; Mary Helen Tran, PharmD, MBA2 guided treatment of spinal synovial cysts: a population- 1University of Utah, Salt Lake City, UT, US; 2Pacira BioSciences, based cohort study Parisppany, NJ, US Alexander Fletcher-Sandersjöö, MD1; Erik Edström, MD, PhD2; Åsa FDA DEVICE/DRUG STATUS: This abstract does not discuss or Kuntze-Söderqvist, MD, PhD1; Per Grane, MD, PhD1; Adrian Elmi include any applicable devices or drugs. Terander, MD, PhD1 1 2 Karolinska University Hospital, Stockholm, Sweden; Karolinska 258. Exploring perioperative complications of anterior University Hospital, Dept Neurosurgery, Solna, Sweden lumber interbody fusion in patients with a history of prior FDA DEVICE/DRUG STATUS: DepoMedrol cum lidocaine; Pfizer, abdominal surgery: a retrospective cohort study (Approved for this indication) Arbaz Momin, BS1; Michael P. Steinmetz, MD2 1Cleveland, OH, US; 2Cleveland Clinic, Cleveland, OH, US 254. Minimally invasive sacroiliac joint fusion with FDA DEVICE/DRUG STATUS: This abstract does not discuss or decortication and bone grafting: 2-year clinical outcomes include any applicable devices or drugs. Donald W. Kucharzyk, DO1; Antoine Tohmeh, MD2 1DK Orthopedics, Crown Point, IN, US; 2MultiCare Neuroscience Institute, Spokane Valley, WA, US FDA DEVICE/DRUG STATUS: SImmetry Sacroiliac Joint Fusion System (Approved for this indication) Abstracts 85

259. Hospital mark-up and outcomes following lumbar 262. Opioid use prior to adult spinal deformity surgery is fusions: moving towards the era of transparency in prices associated with decreased cost effectiveness: a matched cohort analysis Azeem T. Malik, MBBS1; Joseph P. Drain, MD1; Safdar N. Khan, MD1; Jeffery Kim, MD1; Elizabeth Yu, MD2 Breton Line, BS1; Shay Bess, MD2; Samrat Yeramaneni, MBBS, 3 4 5 1The Ohio State University Wexner Medical Center, Columbus, MS, PhD ; Richard A. Hostin Jr., MD ; Christopher P. Ames, MD ; 6 6 OH, US; 2Columbus, OH, US Virginie Lafage, PhD ; Renaud Lafage, MSc ; Douglas C. Burton, MD7; Eric O. Klineberg, MD8; Munish C. Gupta, MD9; Michael P. FDA DEVICE/DRUG STATUS: This abstract does not discuss or Kelly, MD; Gregory M. Mundis Jr., MD10; Robert K. Eastlack, MD11; include any applicable devices or drugs. Peter G. Passias, MD12; Themistocles S. Protopsaltis, MD13; Robert A. Hart, MD14; Khaled M. Kebaish, MD15; Han Jo Kim, MD6; 260. Preoperative medical comorbidities do not affect Frank J. Schwab, MD6; Christopher I. Shaffrey, MD16; Justin S. minimum clinically important difference (MCID) for Smith, MD, PhD17; International Spine Study Group18 lumbar fusion in grade one spondylolisthesis 1Denver International Spine Center, Denver, CO, US; 2Denver, CO, 3 4 Joseph L. Laratta, MD1; Leah Y. Carreon, MD, MSc2; Avery L. US; Sarah Cannon Research Institute, Dallas, TX, US; Southwest 5 Buchholz, MD, MPH3; Andrew Yew, MD4; Erica F. Bisson, MD5; Scoliosis Institute, Dallas, TX, US; University of California, San 6 Steven D. Glassman, MD2 Francisco, San Francisco, CA, US; Hospital for Special Surgery, 7 1 2 New York, NY, US; University of Kansas Medical Center, Kansas Norton Leatherman Spine, Louisville, KY, US; Norton 8 3 City, KS, US; UC, Davis School of Medicine, Sacramento, CA, Leatherman Spine Center, Louisville, KY, US; University of 9 4 US; Washington University School of Medicine, St. Louis, MO, Virginia Health System, Charlottesville, VA, US; Lahey Hospital, 10 5 US; Scripps Clinic Medical Group, Department of Orthopedics, Burlington, MA, US; University of Utah, Dept of Neurosurgery, Salt La Jolla, CA, US; 11Scripps Clinic, San Diego, CA, US; 12NY Spine Lake City, UT, US Institute, NYU Langone Health, New York, NY, US; 13Department FDA DEVICE/DRUG STATUS: This abstract does not discuss or of Orthopaedic Surgery, NYU Langone Orthopaedic Hospital, include any applicable devices or drugs. NYU Langone Health, New York, NY, US; 14Swedish Neuroscience Institute, Seattle, WA, US; 15Johns Hopkins University, Baltimore, MD, US; 16Duke University, Durham, NC, US; 17UVA Health System, 261. Postoperative glycemic variability as a predictor of 18 adverse outcomes following posterior cervical fusion Charlottesville, VA, US; Brighton, CO, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or Parthik Patel, MD1; Jose A. Canseco, MD, PhD2; Fortunato Padua, include any applicable devices or drugs. MD, MSc3; Michael Chang, BA1; Daniel Bowles, MD3; Ariana Reyes, MD4; Mark F. Kurd, MD5; D. Greg Anderson, MD6; Alan S. Hilibrand, MD6; Christopher K. Kepler, MD, MBA6; Gregory D. Schroeder, 263. Detection of scoliosis curve flexibility by means of MD7; Alexander R. Vaccaro, MD, PhD7 MRI 1Philadelphia, PA, US; 2Rothman Institute/Thomas Jefferson Naveed Nabizadeh, MD1; Mohammad E. Majd, MD2; Amir Aghaie University Hospital, Philadelphia, PA, US; 3Rothman Orthopaedic Aghdam, MD3; Hasan Ghandhari, MD4; Farshad Nikouei, MD4 4 Institute, Philadelphia, PA, US; Rothman Orthopaedic Institute, 1Norton Leatherman Spine Center, Louisville, KY, US; 2Baptist Philadelphia, GA, US; 5Rothman Institute, Bryn Mawr, PA, US; 6 7 Health Flyod, Clinical Professor of Indiana University, New Albany, Rothman Institute, Philadelphia, PA, US; Rothman Institute IN, US; 3Shafa Hospital, Islamic Republic of Tehran, Iran; 4Bone Thomas Jefferson University, Philadelphia, PA, US and Joint Reconstruction Research Center, Iran University of FDA DEVICE/DRUG STATUS: This abstract does not discuss or Medical Sciences, Tehran, Iran include any applicable devices or drugs. FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs.

264. Assessment of impact of single photon emission computed tomography (SPECT) on management of degenerative cervical and lumbar disease: a multi- institution survey of spine surgeons Ruwan Ratnayake, MD1; Gregory M. Mundis Jr., MD2; Bahar Shahidi, PT, PhD3; Behrooz A. Akbarnia, MD1; Robert K. Eastlack, MD4 1San Diego Spine Foundation, San Diego, CA, US; 2Scripps Clinic Medical Group, Department of Orthopedics, La Jolla, CA, US; 3University of California San Diego, La Jolla, CA, US; 4Scripps Clinic, San Diego, CA, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. Abstracts 86

265. Lumbar vertebral body Hounsfield units are 270. Patterns of opioid and other prescription medication associated with cage subsidence after transforaminal use in lumbar surgery for spinal stenosis: a national lumbar interbody fusion claims database analysis Donald R. Fredericks Jr., MD1; Alfred J. Pisano, MD1; Melvin D. Tanmaya Sambare, BA; Jayme C.B. Koltsov, PhD; John P. Helgeson, MD2; Scott Wagner, MD1 Kleimeyer, MD; Kirkham B. Wood, MD; Todd F. Alamin, MD; Ivan 1Walter Reed National Military Medical Center, Bethesda, MD, US; Cheng, MD; Serena S. Hu, MD 2North Potomac, MD, US Department of Orthopaedic Surgery, Stanford University School FDA DEVICE/DRUG STATUS: This abstract does not discuss or of Medicine, Redwood City, CA, US include any applicable devices or drugs. FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. 266. Cervical paraspinal muscle fatty degeneration does not relate to muscle cross sectional area: qualitative 271. Surgical technique and patient-reported outcomes in assessment preferable for cervical sarcopenia adult isthmic spondylolisthesis Ashley Xiong, CCRC Daniel Bowles, MD; Jose A. Canseco, MD, PhD; Christopher Mayo Clinic, Rochester, MN, US Antonacci, MS; Aditya Thandoni, BA; D. Greg Anderson, MD; Mark F. Kurd, MD; Alan S. Hilibrand, MD; Christopher K. Kepler, MD, FDA DEVICE/DRUG STATUS: This abstract does not discuss or MBA; Alexander R. Vaccaro, MD, PhD; Gregory D. Schroeder, MD; include any applicable devices or drugs. Ian D. Kaye, MD; Joseph K. Lee, MD Rothman Institute, Thomas Jefferson University, Philadelphia, PA, 267. The impact of preventative multimodal analgesia US on postoperative opioid requirement and pain control in FDA DEVICE/DRUG STATUS: This abstract does not discuss or patients undergoing lumbar fusions include any applicable devices or drugs. Alan T. Villavicencio, MD1; Sharad Rajpal, MD2; Ewell L. Nelson, MD1; Christopher Zielenski, PharmD3; Kara D. Beasley, DO2; Sigita Burneikiene, MD1 272. Timing of preoperative surgical antibiotic prophylaxis prior to one- to three-level elective lumbar 1 2 Boulder Neurosurgical Associates, Boulder, CO, US; Boulder fusion Neurosurgical and Spine Associates, Boulder, CO, US; 3Boulder 1 2 Community Health, Boulder, CO, US Parthik Patel, MD ; Jose A. Canseco, MD, PhD ; Paul Minetos, MD, MBA2; Akash Singh3; Ariana Reyes, MD4; Daniel Bowles, MD5; FDA DEVICE/DRUG STATUS: This abstract does not discuss or Mark F. Kurd, MD6; D. Greg Anderson, MD7; Alan S. Hilibrand, MD7; include any applicable devices or drugs. Christopher K. Kepler, MD, MBA7; Gregory D. Schroeder, MD8; Alexander R. Vaccaro, MD, PhD7 268. Analysis of 27 adolescent idiopathic scoliosis 1Philadelphia, PA, US; 2Rothman Institute/Thomas Jefferson patients corrected with patient specific rods with a University Hospital, Philadelphia, PA, US; 3Sidney Kimmel Medical minimum of 2 years follow-up College, Philadelphia, PA, US; 4Rothman Orthopaedic Institute, 5 Federico Solla, MD1; Antoine Laquievre, MD2; Vincent Cunin, MD3; Philadelphia, GA, US; Rothman Orthopaedics, Philadelphia, PA, 6 7 Jean-Luc Clément, MD1 US; Rothman Institute, Bryn Mawr, PA, US; Rothman Institute, 8 1 Philadelphia, PA, US; Rothman Institute Thomas Jefferson Paediatric Orthopaedic Surgery Unit, Lenval Children’s University, Philadelphia, PA, US Hospital, Nice, France; 2Paediatric Orthopaedic Surgery Unit, Academic Hospital of Caen, Caen, Calvados, France; 3Paediatric FDA DEVICE/DRUG STATUS: This abstract does not discuss or Orthopaedic Surgery Unit, Mother and Child Hospital, Lyon, include any applicable devices or drugs. France FDA DEVICE/DRUG STATUS: UNiD Rod (Approved for this indication)

269. Clinically relevant improvement is maintained five years after surgery for spinal stenosis Andreas K. Andresen, MD1; Christian C. Stoettrup, MD2; Peter Udby, MD3; Rune T. Paulsen, MD4; Soren Fruensgaard, MD5; Leah Y. Carreon, MD, MSc6 1Spine Center of Southern Denmark, Middelfart, Denmark; 2Lillebaelt Hospital, Middelfart, Denmark; 3Zealand University Hospital, Department of Orthopedic Surgery, Køge, Zealand, Denmark; 4Lillebaelt Hospital, Middelfart, Region Syddanmark, Denmark; 5Silkeborg Central Hospital, Silkeborg, Denmark; 6Sygehus Lillebælt - Rygkirurgi Middelfart, Middelfart, Denmark FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. Abstracts 87

273. Economic burden of nonoperative treatment of adult 275. Opioid use after adult spinal deformity surgery: spinal deformity propensity-matched comparison of Japanese versus American cohorts Peter G. Passias, MD1; Waleed Ahmad2; Renaud Lafage, MSc3; Virginie Lafage, PhD3; Eric O. Klineberg, MD4; Khaled M. Kebaish, Jeffrey L. Gum, MD1; Leah Y. Carreon, MD, MSc1; Mitsuru Yagi, MD5; Jeffrey L. Gum, MD6; Michael Kelly, MD7; Breton Line, BS8; MD, PhD2; Naobumi Hosogane, MD, PhD3; Kota Watanabe, MD4; Robert A. Hart, MD9; Douglas C. Burton, MD10; Justin S. Smith, Justin S. Smith, MD, PhD5; Christopher I. Shaffrey, MD6; Han Jo MD, PhD11; Christopher P. Ames, MD12; Christopher I. Shaffrey, Kim, MD7; Eric O. Klineberg, MD8; Virginie Lafage, PhD7; Renaud MD13; Frank J. Schwab, MD3; Richard A. Hostin Jr., MD14; Shay Lafage, MSc7; Themistocles S. Protopsaltis, MD9; Peter G. Bess, MD15; International Spine Study Group16 Passias, MD10; Gregory M. Mundis Jr., MD11; Robert K. Eastlack, 12 13 1NY Spine Institute, NYU Langone Health, New York, NY, US; MD ; Michael P. Kelly, MD; Alan H. Daniels, MD ; Emmanuel 14 15 2New York, NY, US; 3Hospital for Special Surgery, New York, McNeely, MS, MHA ; Alexandra Soroceanu, MD, MPH ; D. Kojo 16 17 18 NY, US; 4UC, Davis School of Medicine, Sacramento, CA, Hamilton, MD ; Munish C. Gupta, MD ; Douglas C. Burton, MD ; 19 20 US; 5Johns Hopkins University, Baltimore, MD, US; 6Norton Richard A. Hostin Jr. , MD ; Khaled M. Kebaish, MD ; Robert A. 21 7 22 Leatherman Spine Center, Louisville, KY, US; 7Cleveland, OH, US; Hart, MD ; Frank J. Schwab, MD ; Shay Bess, MD ; Christopher P. 23 24 8Denver International Spine Center, Denver, CO, US; 9Swedish Ames, MD ; International Spine Study Group Neuroscience Institute, Seattle, WA, US; 10University of Kansas 1Norton Leatherman Spine Center, Louisville, KY, US; 2Department Medical Center, Kansas City, KS, US; 11UVA Health System, of Orthopedic Surgery, Keio University School of Medicine, Charlottesville, VA, US; 12University of California, San Francisco, Tokyo, Japan; 3Kyorin University, Mitaka, Tokyo, Japan; 4Keio San Francisco, CA, US; 13Duke University, Durham, NC, US; University, Keio, Japan; 5UVA Health System, Charlottesville, 14Southwest Scoliosis Institute, Dallas, TX, US; 15Denver, CO, US; VA, US; 6Duke University, Durham, NC, US; 7Hospital for Special 16Brighton, CO, US Surgery, New York, NY, US; 8UC, Davis School of Medicine, 9 FDA DEVICE/DRUG STATUS: This abstract does not discuss or Sacramento, CA, US; Department of Orthopaedic Surgery, NYU include any applicable devices or drugs. Langone Orthopaedic Hospital, NYU Langone Health, New York, NY, US; 10NY Spine Institute, NYU Langone Health, New York, NY, US; 11Scripps Clinic Medical Group, Department of Orthopedics, 274. Not without my attending: a survey of public La Jolla, CA, US; 12Scripps Clinic, San Diego, CA, US; 13Warren attitudes and perceptions of concurrent and overlapping Alpert Medical School of BU/RI Hospital, Providence, RI, US; surgery 14The Johns Hopkins Hospital, Baltimore, MD, US; 15University 16 Andrew Kim, MS1; Ram K. Alluri, MD2; Hyunwoo P. Kang, MD3; of Calgary, Calgary, Canada; University of Pittsburgh School 17 Jeffrey C. Wang, MD4; Raymond J. Hah, MD5 of Medicine, Pittsburgh, PA, US; Washington University School 18 1 2 3 of Medicine, St. Louis, MO, US; University of Kansas Medical Oak Park, IL, US; LAC USC, Los Angeles, CA, US; University of 19 4 Center, Kansas City, KS, US; Southwest Scoliosis Institute, Southern California, Los Angeles, CA, US; USC Spine Center, Los 20 5 Dallas, TX, US; Johns Hopkins University, Baltimore, MD, US; Angeles, CA, US; Keck School of Medicine of USC, Los Angeles, 21Swedish Neuroscience Institute, Seattle, WA, US; 22Denver, CO, CA, US US; 23University of California, San Francisco, San Francisco, CA, FDA DEVICE/DRUG STATUS: This abstract does not discuss or US; 24Brighton, CO, US include any applicable devices or drugs. FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs.

276. Average lumbar Hounsfield units predicts osteoporosis related complications following lumbar spine fusion Taylor Jackson, MD1; Jeffery D. St. Jeor, BS2; Ashley Xiong, CCRC1; Brett A. Freedman, MD1; Arjun S. Sebastian, MD, MSc1; Bradford L. Currier, MD1; Ahmad N. Nassr, MD3; Benjamin D. Elder, MD, PhD2 1Mayo Clinic, Rochester, MN, US; 2Rochester, MN, US; 3Mayo Clinic/Dept of Orthopedic Surgery, Rochester, MN, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. Abstracts 88

277. Is adjacent segment disease following instrumented 282. Establishment of an individualized distal junctional short lumbosacral fusion influenced by postoperative kyphosis risk index taking into account radiographic and sagittal alignment? surgical components Joshua Bell, MD1; Chelsea D. Frost, MD, MS2; Minghui Huang1; Peter G. Passias, MD1; Sara Naessig, BS2; Katherine E. Pierce, Varun Puvanesarajah, MD3; Manminder S. Bhatia, DO4; Amit Jain, BS3; Renaud Lafage, MSc4; Virginie Lafage, PhD4; Robert K. MD5; Hamid Hassanzadeh, MD1; Adam L. Shimer, MD1; Francis H. Eastlack, MD5; Alan H. Daniels, MD6; Themistocles S. Protopsaltis, Shen, MD1 MD7; Eric O. Klineberg, MD8; Gregory M. Mundis Jr., MD9; Robert 10 11 12 1University of Virginia, Department of Orthopaedics, A. Hart, MD ; Douglas C. Burton, MD ; Shay Bess, MD ; Frank 4 13 Charlottesville, VA, US; 2University of Virginia, Charlottesville, VA, J. Schwab, MD ; Christopher I. Shaffrey, MD ; Justin S. Smith, 14 15 US; 3Johns Hopkins Medicine, Baltimore, MD, US; 4Crozet, VA, US; MD, PhD ; Christopher P. Ames, MD ; International Spine Study 16 5Dept of Orthopaedic Surgery, Baltimore, MD, US Group 1 2 FDA DEVICE/DRUG STATUS: This abstract does not discuss or NY Spine Institute, NYU Langone Health, New York, NY, US; NYU 3 include any applicable devices or drugs. Langone Hospital, New York NY, US; NYU Spine Research Lab, New York, NY, US; 4Hospital for Special Surgery, New York, NY, US; 5Scripps Clinic, San Diego, CA, US; 6Warren Alpert Medical 278. Allograft reconstructed iliac bone graft donor site School of BU/RI Hospital, Providence, RI, US; 7Department remodels to viable bone and its preliminary clinical of Orthopaedic Surgery, NYU Langone Orthopaedic Hospital, effectiveness in revision fusion NYU Langone Health, New York, NY, US; 8UC, Davis School 9 Glenn R. Buttermann, MD1; Andrew L. Freeman2; Byron Simmons, of Medicine, Sacramento, CA, US; Scripps Clinic Medical 10 MD3 Group, Department of Orthopedics, La Jolla, CA, US; Swedish 11 1 2 Neuroscience Institute, Seattle, WA, US; University of Kansas Midwest Spine Institute, Stillwater, MN, US; Fortus Medical, 12 13 3 Medical Center, Kansas City, KS, US; Denver, CO, US; Duke Minneapolis, MN, US; St. Joseph’s Hospital, St. Paul, MN, US University, Durham, NC, US; 14UVA Health System, Charlottesville, FDA DEVICE/DRUG STATUS: This abstract does not discuss or VA, US; 15University of California, San Francisco, San Francisco, include any applicable devices or drugs. CA, US; 16Brighton, CO, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or 279. Indications, survival and cause of death after surgery include any applicable devices or drugs. for spinal metastatic disease: a retrospective study of 1,820 patients in Sweden 2006-2016 283. The position of the L1 vertebra relative to the gravity Christian Carrwik, MD1; Claes Olerud, MD, PhD2; Yohan Robinson, line does not appear to correlate with proximal junctional MD, PhD, MBA3 kyphosis following adult spinal deformity surgery with 1Uppsala University Hospital, Uppsala, Sweden; 2Dept two year follow up Orthopaedics, Uppsala, Uppsala, Sweden; 3Gothenburg University, Zhuo Xi, MD, PhD1; Ping G. Duan, PhD, MD2; Joshua Rivera3; Västra Frölunda, Sweden Shane Burch, MD4; Sigurd H. Berven, MD5; Dean Chou, MD4 FDA DEVICE/DRUG STATUS: This abstract does not discuss or 1Neurosurgery Department Shengjing Hospital of China Medical include any applicable devices or drugs. University, Liaoning, Shenyang, China; 2UCSF Spine Center, University of California San Francisco, San Francisco, CA, US; 3San Francisco, CA, US; 4University of California San Francisco, 280. The risk factors of respiratory complications after 5 posterior spine deformity surgery for patients with early San Francisco, CA, US; UCSF, Dept of Orthopaedic Surgery, San onset scoliosis Francisco, CA, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or Ying Zhang, MD; Yingsong Wang, MD; Jing-Ming Xie, MD1; Quan include any applicable devices or drugs. Li, MD; Tao Li, MD; Zhi Zhao, MD; Zhiyue Shi, MD; Ni Bi, MD Department of Orthopaedics, 2nd Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, China 284. Activity goals of patients considering spine surgery: a pilot study FDA DEVICE/DRUG STATUS: This abstract does not discuss or 1 2 include any applicable devices or drugs. Mustfa K. Manzur, MPH, MS, BS ; Yahya A. Othman ; Arjun Khorana3; Avani S. Vaishnav, MBBS; Michelle Richardson, BS4; Han Jo Kim, MD3; James C. Farmer, MD3; Russel C. Huang, MD3; 281. Defining spino-pelvic alignment goals for adult Sravisht Iyer, MD3; Harvinder S. Sandhu, MD3; Todd J. Albert, MD3; spinal deformity surgery that optimize outcomes by Mark Fontana, PhD3; Catherine MacLean, MD, PhD3; Catherine incorporating age and frailty status Himo Gang, MPH3; Sheeraz A. Qureshi, MD, MBA3 Peter G. Passias, MD1; Katherine E. Pierce, BS2; Sara Naessig, 1Thomas Jefferson University, Philadelphia, PA, US; 2Weill Cornell BS3; Waleed Ahmad4; Bassel G. Diebo, MD5; Renaud Lafage, MSc6; Medicine, Qatar Foundation, Rayyan, Qatar; 3Hospital For Special Virginie Lafage, PhD6 Surgery, New York City, NY, US; 4Rochester, NY, US 1NY Spine Institute, NYU Langone Health, New York, NY, US; 2NYU FDA DEVICE/DRUG STATUS: This abstract does not discuss or Spine Research Lab, New York, NY, US; 3NYU Langone Hospital, include any applicable devices or drugs. New York NY, US; 4New York, NY, US; 5Department of Orthopaedic Surgery, SUNY Downstate Medical Center, Brooklyn, NY, US; 6Hospital for Special Surgery, New York, NY, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. Abstracts 89

285. Choosing touched vertebrae with grade 0/1 rotation 289. Risk of spinal surgery amongindividuals who have on lying down x-rays saves fusion levels, decreases risk of been re-vascularized for coronary artery disease adding on, and prevents translation Peter G. Passias, MD1; Waleed Ahmad2; Joshua Bell, MD3; Sara Vishal Sarwahi, MD1; Jesse M. Galina, BS2; Sayyida S. Hasan, BS3; Naessig, BS4; Katherine E. Pierce, BS5; Frank A. Segreto, BS6; Aaron M. Atlas, BS4; Stephen Wendolowski3; Yungtai Lo, PhD5; Shaleen N. Vira, MD7; Virginie Lafage, PhD8; Bassel G. Diebo, MD9; Terry D. Amaral, MD6 Hamid Hassanzadeh, MD10 1North Shore LIJ Health System, New Hyde Park, NY, US; 2New 1NY Spine Institute, NYU Langone Health, New York, NY, US; 2New Hyde Path, NY, US; 3Cohen Children’s Medical Center, New Hyde York, NY, US; 3University of Virginia, Department of Orthopaedics, Park, NY, US; 4Cohen Children’s Medical Center, New Hyde Park, Charlottesville, VA, US; 4NYU Langone Hospital, New York NY, NY, US; 5Albert Einstein College of Medicine, Bronox, NY, US; US; 5NYU Spine Research Lab, New York, NY, US; 6NYU Langone 6Northwell Health, Lake Success, NY, US Medical Center - Orthopaedic Hospital, Manhattan, NY, US; 7 FDA DEVICE/DRUG STATUS: This abstract does not discuss or Department of Orthopaedic Surgery, UT Southwestern Medical 8 include any applicable devices or drugs. Center, Dallas, TX, US; Hospital for Special Surgery, New York, NY, US; 9Department of Orthopaedic Surgery, SUNY Downstate Medical Center, Brooklyn, NY, US; 10University of Virginia, 286. Incidence, prognosis, and risk factors for bladder and Department of Orthopedic Surgery, Charlottesville, VA, US bowel dysfunction due to incidental dural tears in lumbar FDA DEVICE/DRUG STATUS: This abstract does not discuss or microendoscopic surgery include any applicable devices or drugs. Masahito Oshina, MD1; Yasushi Oshima, MD, PhD2 1 2 NTT Medical Center Tokyo, Tokyo, Japan; University of Tokyo 290. The impact of insurance payor on hospital length Hospital, Tokyo, Japan of stay and discharge time in adult patients undergoing FDA DEVICE/DRUG STATUS: This abstract does not discuss or elective spine surgery include any applicable devices or drugs. Luke Dosselman, BS1; Salah Aoun, MD2; Najib El Tecle, MD3; Brandon Lopez4; Kristen Hall, BS5; Valery Peinado Reyes, PA- 287. Early postoperative physical activity predicts clinical C5; Emmanuel Adeyemo, BA5; Zachary Christian, BA1; Carlos A. improvement in disability 1-year following spine surgery Bagley, MD5 1 2 3 Hiral Master, PhD, PT, MPH1; Jacquelyn S. Pennings, PhD1; Dallas, TX, US; UTSW, Dallas, TX, US; St Louis University 4 Rogelio A. Coronado, PT, PhD1; Payton Robinette, BA1; Christine Hospital, Saint Louis, MO, US; UT Southwestern, Dallas, TX, US; 5 Haug, MPH, CCRP2; Richard L. Skolasky, ScD3; Lee H. Riley III, UT Southwestern Medical Center, Dallas, TX, US MD4; Brian J. Neuman, MD5; Joseph S. Cheng, MD, MS6; Oran S. FDA DEVICE/DRUG STATUS: This abstract does not discuss or Aaronson, MD7; Clinton J. Devin, MD1; Stephen Wegener, PhD8; include any applicable devices or drugs. Kristin R. Archer, PhD, DPT1

1 Vanderbilt University Medical Center, Nashville, TN, US; 291. Adjustment of the global alignment and proportion 2 Carolina Neurosurgery & Spine Associates, Charlotte, NC, US; scores accounting for frailty in adult spinal deformity 3 4 Johns Hopkins University, Baltimore, MD, US; Johns Hopkins surgical patients Outpatient Ctr/Dept Ortho Surgery, Baltimore, MD, US; 5Baltimore, 1 2 MD, US; 6University of Cincinnati College of Medicine, Cincinnati, Peter G. Passias, MD ; Katherine E. Pierce, BS ; Sara Naessig, 3 4 4 OH, US; 7Howell Allen Clinic, Nashville, TN, US; 8Johns Hopkins, BS ; Waleed Ahmad ; Tina Raman, MD ; Constance Maglaras, 4 5 6 Baltimore, MD, US PhD ; Frank J. Schwab, MD ; Aaron J. Buckland, MBBS, FRACS ; Themistocles S. Protopsaltis, MD6; Bassel G. Diebo, MD7; Renaud FDA DEVICE/DRUG STATUS: This abstract does not discuss or Lafage, MSc5; Virginie Lafage, PhD5 include any applicable devices or drugs. 1NY Spine Institute, NYU Langone Health, New York, NY, US; 2NYU Spine Research Lab, New York, NY, US; 3NYU Langone 288. Recent trends in spinal surgery performed by Hospital, New York, NY, US; 4New York, NY, US; 5Hospital for American Board of Orthopaedic Surgery (ABOS) part II Special Surgery, New York, NY, US; 6Department of Orthopedic candidates (2008-2017) Surgery, NYU Langone Orthopedic Hospital, NYU Langone Health, 7 Caleb Yeung, MD1; Andrew J. Schoenfeld, MD2; Harry M. Lightsey, New York, NY, US; Department of Orthopaedic Surgery, SUNY IV, MD2; James D. Kang, MD2; Melvin C. Makhni, MD, MBA2 Downstate Medical Center, Brooklyn, NY, US 1Boston, MA, US; 2Brigham and Women’s Hospital, Boston, MA, FDA DEVICE/DRUG STATUS: This abstract does not discuss or US include any applicable devices or drugs. FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. 292. Global Alignment and Proportion (GAP) score with modified age factor: GAP-A score Woojin Cho, MD, PhD; Adam D. Nessim, BS; Jeffrey Kim, MD; Ariella Applebaum, BA Bronx, NY, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. Abstracts 90

293. The modified adult spinal deformity frailty index 296. Residual coronal malalignment results in less (mASD-FI) is a good preoperative risk assessment tool improvement in pain and disability after ASD surgery Katherine E. Pierce, BS1; Waleed Ahmad2; Sara Naessig, BS3; Amit Jain, MD1; Emmanuel McNeely, MS, MHA2; Brian J. Bassel G. Diebo, MD4; Peter G. Passias, MD5 Neuman, MD3; Jeffrey L. Gum, MD4; Shay Bess, MD5; Richard A. 6 7 1NYU Spine Research Lab, New York, NY, US; 2New York, NY, Hostin Jr., MD ; Virginie Lafage, PhD ; Samrat Yeramaneni, MBBS, 8 9 7 US; 3NYU Langone Hospital, New York, NY, US; 4Department of MS, PhD ; Eric O. Klineberg, MD ; Renaud Lafage, MSc ; Munish 10 11 Orthopaedic Surgery, SUNY Downstate Medical Center, Brooklyn, C. Gupta, MD ; Justin S. Smith, MD, PhD ; Douglas C. Burton, 12 13 14 NY, US; 5NY Spine Institute, NYU Langone Health, New York, NY, MD ; Peter G. Passias, MD ; Themistocles S. Protopsaltis, MD ; 15 16 US Khaled M. Kebaish, MD ; International Spine Study Group 1 2 FDA DEVICE/DRUG STATUS: This abstract does not discuss or Dept of Orthopaedic Surgery, Baltimore, MD, US; The Johns 3 4 include any applicable devices or drugs. Hopkins Hospital, Baltimore, MD, US; Baltimore, MD, US; Norton Leatherman Spine Center, Louisville, KY, US; 5Denver, CO, US; 6Southwest Scoliosis Institute, Dallas, TX, US; 7Hospital for 294. Ambulatory neuromuscular scoliosis patients have Special Surgery, New York, NY, US; 8Sarah Cannon Research similar rates of infection, perioperative complications, Institute, Dallas, TX, US; 9UC, Davis School of Medicine, and revision to adolescent idiopathic scoliosis patients Sacramento, CA, US; 10Washington University School of Medicine, 11 Vishal Sarwahi, MD1; Aaron M. Atlas, BS2; Jesse M. Galina, BS3; St. Louis, MO, US; UVA Health System, Charlottesville, VA, US; 12 Sayyida S. Hasan, BS2; Yungtai Lo, PhD4; Marina Moguilevitch, University of Kansas Medical Center, Kansas City, KS, US; 13 MD5; Chhavi Katyal, MD6; Terry D. Amaral, MD7 NY Spine Institute, NYU Langone Health, New York, NY, US; 14 1 2 Department of Orthopaedic Surgery, NYU Langone Orthopaedic North Shore LIJ Health System, New Hyde Park, NY, US; Cohen 15 3 Hospital, NYU Langone Health, New York, NY, US; Johns Children’s Medical Center, New Hyde Park , NY, US; New Hyde Hopkins University, Baltimore, MD, US; 16Brighton, CO, US Path, NY, US; 4Albert Einstein College of Medicine, Bronox, NY, US; 5Montefiore Medical Center, Bronx, NY, US;6 Children’s Hospital at FDA DEVICE/DRUG STATUS: This abstract does not discuss or Montefiore Medical Center, Bronx, CT, US;7 Northwell Health, Lake include any applicable devices or drugs. Success, NY, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. Research Grant Award Winner Presentations 295. Should selective thoracic fusion be reserved for non- structural compensatory lumbar curves? Radiographic 2016 Research Grant Award Winner and clinical results from propensity score matched The severity of preoperative HbA1c and predicting patients at minimum five year follow up postoperative complications in spine surgery 2 Jay S. Reidler, MD, MPH4; Scott L. Zuckerman, MD5; Andrew C. Tomoko Tanaka MD1; Toby Bradford, MD, BS ; Michael Gardner, Vivas, MD4; Joseph M. Lombardi, MD4; Jun S. Kim, MD2; Meghan MD3; Norman S. Litofsky, MD4 Cerpa, MPH4; Lawrence G. Lenke, MD3 1Arkansas Children’s Hospital, Little Rock, AR, US; 2Highland 1Johns Hopkins Hospital, Baltimore, MD, US; 2New York, NY, US; Hospital, Oakland, CA, US; 3University of Missouri, Columbia, MO, 3Columbia University Department of Orthopedic Surgery, New US; 4UMHC Division of Neurosurgery, Columbia, MO, US York, NY, US, 5Jane Och Spine Hospital, New York-Presbyterian/ FDA DEVICE/DRUG STATUS: This abstract does not discuss or Allen Hospita, Columbia University Medical Center, New York, NY, include any applicable devices or drugs. US FDA DEVICE/DRUG STATUS: This abstract does not discuss or 2017 Research Grant Award Winner include any applicable devices or drugs. Real-time non-radiation-based navigation using 3D ultrasound for pedicle screw placement Ilker Hacihaliloglu, PhD1; Michael J. Vives, MD2 1Department of Biomedical Engineering, Rutgers University, Piscataway, NJ, US; 2Department of Orthopedics, Rutgers New Jersey Medical School, Newark, NJ, US FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. Abstracts 91

2018 Research Grant Award Winner P3. The impact of osteobiologic subtype selection on Epidural electrical stimulation assisted gait perioperative complications and cost in single- and multi- improvements in spinal cord injured rats using a level lumbar spinal fusion combinatorial strategy with scaffolds, compounds, cells, Shane Shahrestani, MS1; Alexander Ballatori, BA2; Xiao Chen, BA2; and motor training Andy Ton, BS3; Jeffrey C. Wang, MD4; Zorica Buser, PhD5 1 1 Anthony J. Windebank, MD ; Ahad M. Siddiqui, PhD ; Riazul 1Yorba Linda, CA, US; 2Los Angeles, CA, US; 3Anaheim, CA, 2 3 1 Islam, MBA ; Carlos Cuellar, PhD ; Jodi Silvernail ; Bruce Knudsen, US; 4USC Spine Center, Los Angeles, CA, US; 5Keck School of 4 5 6 BS, MS ; Dallece Curley, BS ; Tammy Strickland, MSc ; Emilee Medicine, University of Southern California, Los Angeles, CA, US Manske2; Timur Latypov, MD7; Shuya Zhang, BS1; Priska Summer, MD1; Jarred J. Nesbitt, BS1; Bingkun Chen, MD, PhD8; Peter Grahn, FDA Device/Drug Status: This abstract does not discuss or PhD1; Nicolas N. Madigan, MbChB, PhD1; Michael J. Yaszemski, include any applicable devices or drugs. MD, PhD2; Igor Lavrov, MD, PhD1 1Mayo Clinic, Rochester, MN, US; 2Rochester, MN, US; P4. In vitro assessment of adjustable lordotic expandable 3Universidad Anáhuac México, Huixquilucan, Estado de México, lateral interbody spacers on endplate loading and lordosis State of Mexico, Mexico; 4Mayo Foundation for Medical correction 5 Education and Research, Rochester, MN, US; Brown University, Ripul R. Panchal, DO, FACS1; Dhara Amin, PhD2; May Allall2; 6 7 8 Providence, RI, US; Dublin, Ireland; Rochester, ON, US; Mayo Jonathan Harris2; Brandon Bucklen, PhD2 Clinic in Rochester, Rochester, MN, US 1American Neurospine Institute, PLLC, Plano, TX, US; 2Globus FDA DEVICE/DRUG STATUS: Rapamycin (Approved for Medical, Audubon, PA, US this indication), Oligopolyethylene glycol hydrogel scaffold, Schwann cell delivered Glial derived neurotrophic factor (GDNF) FDA Device/Drug Status: This abstract does not discuss or (Investigational, Not approved for this indication). include any applicable devices or drugs.

2018 Research Grant Award Winner P5. In vitro comparison of novel adjustable-lordotic Nutrient supply and nucleus pulposus cell function: expandable and static hyperlordotic lateral interbody effects of cartilage endplate permeability and potential spacers on endplate loading and lordosis correction implications for intradiscal biologic therapy Ripul R. Panchal, DO, FACS1; Dhara Amin, PhD2; May Allall2; 2 2 Jason Wong, MD1; Aaron Dolor, PhD2; Mohamed Habib, PhD2; Jonathan Harris ; Brandon Bucklen, PhD Jeffrey C. Lotz, PhD2, Aaron J. Fields, PhD2 1American Neurospine Institute, Plano, TX, US; 2Globus Medical, 1Cedars Sinai Medical Center, Los Angeles, CA, US; 2University of Audubon, PA, US California San Francisco, San Francisco, CA, US FDA Device/Drug Status: This abstract does not discuss or FDA DEVICE/DRUG STATUS: Human recombinant MMP-8, include any applicable devices or drugs. Clostridium collagenase (Not approved for this indication). P6. A roughened 3D-printed surface enhances stem cell proliferation and osteoblast differentiation Basic Science/Biologics ePosters Margaret R. Van Horn, PhD; Roland Beard, MS; Brandon Bucklen, PhD P1. How important is the anterior column support in a long lumbopelvic spinal fixation? An in-silico biomechanics Globus Medical, Audubon, PA, US analysis FDA Device/Drug Status: SABLE (Globus Medical) (Approved for Woojin Cho, MD, PhD1; Wenhai Wang, PhD2; Brandon Bucklen, this indication) PhD2; Rafael De la Garza Ramos, MD3; Reza Yassari, MD, MSc4 1Bronx, NY, US; 2Globus Medical, Audubon, PA, US; 3Montefiore P7. Hierarchical surface roughness produced with Medical Center, Department of Neurosurgery, Spine Research additive manufacturing technology significantly Group, Bronx, NY, US; 4Montefiore Medical Center, Bronx, NY, US increases osteogenic cellular differentiation and gene FDA Device/Drug Status: This abstract does not discuss or expression when compared to PEEK and smooth titanium include any applicable devices or drugs. surfaces David Rowe, MD P2. To cross or not to cross: a biomechanical investigation UConn Fluoresence Imaging Core, Farmington, CT, US of crossing cervicothoracic junction in posterior cervical FDA Device/Drug Status: This abstract does not discuss or laminectomy and fusion include any applicable devices or drugs. Yaroslav J. Gelfand, MD1; Jonathan Harris2; Merritt Kinon, MD3; Rafael De la Garza Ramos, MD3; Jorge Gonzalez2; Reza Yassari, MD, MSc1; Brandon Bucklen, PhD2 1Montefiore Medical Center, Bronx, NY, US;2 Globus Medical, Audubon, PA, US; 3Montefiore Medical Center, Department of Neurosurgery, Spine Research Group, Bronx, NY, US FDA Device/Drug Status: QUARTEX (Globus Medical) (Approved for this indication) Abstracts 92

P8. Biomechanical analysis of standalone lumbar Biomechanics ePosters interbody cages versus 360-degree constructs: an in vitro and finite element investigation P11. How much lumbar lordosis does a patient need to Ali Kiapour, PhD1; Vijay K. Goel, PhD2; Elie Massaad, MD1; John H. reach their age-adjusted alignment target? A formulated Shin, MD3 approach predicting successful surgical outcomes 1Boston, MA, US; 2University of Toledo, Toledo, OH, US; Michael H. McCarthy, MD, MPH Renaud Lafage, MSc1; Justin S. 3Massachusetts General Hospital, Boston, MA, US Smith, MD, PhD2; Shay Bess, MD3; Themistocles S. Protopsaltis, 4 5 6 FDA Device/Drug Status: This abstract does not discuss or MD ; Christopher P. Ames, MD ; Eric O. Klineberg, MD ; Han Jo 1 7 8 include any applicable devices or drugs. Kim, MD ; Christopher I. Shaffrey, MD ; Douglas C. Burton, MD ; Gregory M. Mundis Jr., MD9; Munish C. Gupta, MD10; Frank J. Schwab, MD1; Virginie Lafage, PhD1; International Spine Study P9. Early and sustained improvements in motor function Group11 in rats after infusion of allogeneic umbilical cord derived 1 2 mesenchymal stem cells following spinal cord injury Hospital for Special Surgery, New York, NY, US; UVA Health System, Charlottesville, VA, US; 3Denver, CO, US; 4Department Mohamad Bydon, MD of Orthopaedic Surgery, NYU Langone Orthopaedic Hospital, Mayo Clinic, Rochester, MN, US NYU Langone Health, New York, NY, US; 5University of California, San Francisco, San Francisco, CA, US; 6UC, Davis School of FDA Device/Drug Status: This abstract does not discuss or Medicine, Sacramento, CA, US; 7Duke University, Durham, NC, include any applicable devices or drugs. US; 8University of Kansas Medical Center, Kansas City, KS, US; 9Scripps Clinic Medical Group, Department of Orthopedics, La P10. Bone morphogenetic protein usage decreases the Jolla, CA, US; 10Washington University School of Medicine, St. risk of reoperations after anterior cervical discectomy and Louis, MO, US; 11Brighton, CO, US fusion: a five-year survivorship analysis FDA Device/Drug Status: This abstract does not discuss or Waleed Ahmad1; Joshua Bell, MD2; Katherine E. Pierce, BS3; include any applicable devices or drugs. Sara Naessig, BS4; Frank A. Segreto, BS5; Shaleen N. Vira, MD6; Virginie Lafage, PhD7; Carl B. Paulino, MD8; Andrew J. Schoenfeld, 9 10 2 P12. Lumbosacral residual rod strains in long PSR MD ; Bassel G. Diebo, MD ; Hamid Hassanzadeh, MD ; Peter G. constructs often exceed in vitro rod bending strains Passias, MD11 Anna G. Newcomb, MS1; Taylor Hostetler, BS2; Jennifer 1New York, NY, US; 2University of Virginia, Department of Lehrman, MS2; Bernardo De Andrada Pereira, MD3; Piyanat Orthopaedics, Charlottesville, VA, US; 3NYU Spine Research Lab, Wangsawatwong, MD2; Jay D. Turner, MD, PhD4; Brian Kelly, PhD2 New York, NY, US; 4NYU Langone Hospital, New York NY, US; 5NYU Langone Medical Center - Orthopaedic Hospital, Manhattan, 1St. Joseph’s Hospital and Medical Center, Phoenix, AZ, US; NY, US; 6Department of Orthopaedic Surgery, UT Southwestern 2Barrow Neurological Institute, Phoenix, AZ, US; 3Phoenix, AZ, US; Medical Center, Dallas, TX, US; 7Hospital for Special Surgery, New 4Barrow Brain and Spine, Phoenix, AZ, US York, NY, US; 8SUNY Downstate Medical Center, Brooklyn, NY, US; FDA Device/Drug Status: PSR (Approved for this indication) 9Brigham and Women’s Hospital, Boston, MA, US; 10Department of Orthopaedic Surgery, SUNY Downstate Medical Center, Brooklyn, NY, US; 11NY Spine Institute, NYU Langone Health, P13. ACDF fusion rates New York, NY, US; 10Department of Orthopaedic Surgery, SUNY Noah Nichols, BS1; Dean Chou, MD2; Alysha Jamieson3; Lee A. Downstate Medical Center, Brooklyn, NY, US; 11NY Spine Institute, Tan, MD2 NYU Langone Health, New York, NY, US 1San Francisco, CA, US; 2University of California San Francisco, FDA Device/Drug Status: This abstract does not discuss or San Francisco, CA, US; 3UCSF Spine Center, San Francisco, CA, include any applicable devices or drugs. US FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs.

P14. Analysis of the segmental and adjacent level impacts of forcing the connection of misaligned pedicle screws and rods and subsequent unintended forces applied to the construct and spine: a finite element analysis David Cesar Noriega Gonzalez, MD, PhD1; Arjan Loenen, MSc2; Pierce D. Nunley, MD3; Jerome Noailly, PhD4; Keita Ito, MD2; Bert van Rietbergen, PhD2 1Valladolid, Spain; 2Eindhoven University of Technology, Eindhoven, Noord-Brabant, Netherlands; 3Spine Institute of Louisiana, Shreveport, LA, US; 4Universitat Pompeu Fabra (UPF), Barcelona, Spain FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. Abstracts 93

P15. Power-assisted pedicle screw placement decreases P19. Development and validation of machine learning screw wobble algorithms for predicting adverse events following David L. Skaggs, MD1; Amy Claeson, PhD2; Frank J. Schwab, MD3; surgery for metastatic spine tumors: metastatic adverse Anup Gandhi, PhD2 events scoring system (MAES). 1Childrens Hospital Los Angeles, Los Angeles, CA, US; 2Zimmer Nida Fatima, MD, MBBS; Elie Massaad, MD; Muhamed Biomet, Westminster, CO, US; 3Hospital for Special Surgery, New Hadzipasic, MD, PhD; Ganesh M. Shankar, MD, PhD; John H. Shin, York, NY, US MD FDA Device/Drug Status: This abstract does not discuss or Department of Neurosurgery, Massachusetts General Hospital, include any applicable devices or drugs. Harvard Medical School, Boston, MA, US FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. P16. Spinopelvic deformities and postural malalignment affect gait patterns in ASD patients Georges Kawkabani, MD, MSc1; Renee Maria Saliby, MD2; Mario P20. Surgical site infection as a risk factor for long-term Mekhael, MSc2; Eddy Saad, BS2; Rami El Rachkidi, MD, MSc1; instrumentation failure in patients with spinal deformity: Ismat Ghanem, MD3; Khalil E. Kharrat Sr., MD4; Virginie Lafage, a retrospective cohort study PhD5; Renaud Lafage, MSc5; Wafa Skalli, PhD6; Ayman Assi, PhD7 Joseph P. Gjolaj, MD, FACS 1Hotel dieu de france, Beirut, Lebanon; 2Beirut, Lebanon; University of Miami & Jackson Memorial Hospital Department of 3University of Saint-Joseph, Beirut, Lebanon; 4Hotel-Dieu Hospital, Orthopaedic Surgery, Miami, FL, US 5 Beyrouth, Lebanon; Hospital for Special Surgery, New York, NY, FDA Device/Drug Status: This abstract does not discuss or 6 US; Institut de Biomecanique Humaine Georges Charpak, Paris, include any applicable devices or drugs. France; 7University of Saint Joseph, Faculty of Medicine, Beirut, Lebanon P21. Inpatient outcomes after elective lumbar spinal FDA Device/Drug Status: This abstract does not discuss or fusion for patients with human Immunodeficiency virus in include any applicable devices or drugs. the absence of acquired immunodeficiency syndrome Joseph P. Gjolaj, MD, FACS1; Chester J. Donnally III, MD2; P17. Investigating the effects of cage width and Alexander J. Butler, MD3; Karthik Madhavan, MD placement on subsidence performance using 1 anatomically representative models University of Miami & Jackson Memorial Hospital Department of Orthopaedic Surgery, Miami, FL, US; 2Philadelphia, PA, US; 1 2 2 Guy R. Fogel, MD ; Christian Yee-Yanagishita ; Jeremy Malik ; 3University of Miami, Miami, FL, US Brooke Douglas3; Yun Peng2; Michael Jekir3 FDA Device/Drug Status: This abstract does not discuss or 1 2 Spinepainbegone, San Antonio, TX, US; NuVasive, San Diego, include any applicable devices or drugs. CA, US; 3San Diego, CA, US FDA Device/Drug Status: Modulus XLIF (Approved for this P22. Local retropharyngeal space anesthetic for indication) dysphagia reduction after anterior cervical discectomy and fusion surgery: a single-center, prospective, randomized, double-blinded, placebo-controlled clinical Complications ePosters trial Alan T. Villavicencio, MD1; Ewell L. Nelson, MD1; Sharad Rajpal, P18. Peri-incisional subcutaneous fat thickness is MD2; Kara D. Beasley, DO2; Sigita Burneikiene, MD1 associated with infection after posterior lumbar surgery in obese patients: a propensity score matched 1Boulder Neurosurgical Associates, Boulder, CO, US; 2Boulder retrospective study Neurosurgical and Spine Associates, Boulder, CO, US Dong Hu, MD1; Dong Yang, MD, PhD2; Songhua Xiao, MD3 FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. 1Beijing Tsinghua Changguang Hospital, Beijing, China; 2Department of Orthopedic, First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China; 3Department of Orthopedic, Beijing Tsinghua Changgung Hospital, Beijing, China

FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. Abstracts 94

P23. Does prior cervical fusion (CF) affect PJK rate and UIV P27. Who is at risk of developing postoperative urinary level selection in thoracolumbar fusion surgery for adult retention following spine surgery? A retrospective study spinal deformity (ASD)? suggests think ABC! Gregory M. Mundis Jr., MD1; Renaud Lafage, MSc2; Virginie Richard W. Easton, MD1; Nicholas S. Papakonstantinou, MD1; Lafage, PhD2; Robert K. Eastlack, MD3; Eric O. Klineberg, MD4; Christopher A. Hulen, MD1; Brady Vibert, MD1; Matthew Lipphardt, Peter G. Passias, MD5; Themistocles S. Protopsaltis, MD6; MD2; Bradley Ahlgren, MD1; Patrick Karabon, MS3; Cecile Pestano, Alexandra Soroceanu, MD, MPH7; Christopher I. Shaffrey, MD8; RN, BSN, CCRP1 9 10 Justin S. Smith, MD, PhD ; Shay Bess, MD ; Khaled M. Kebaish, 1Michigan Orthopaedic Spine Surgeons, Rochester Hills, MI, 11 12 13 MD ; Munish C. Gupta, MD ; Richard A. Hostin Jr., MD ; Michael US; 2Beaumont Health System, Royal Oak, MI, US 3Oakland 14 2 14 P. Kelly, MD ; Han Jo Kim, MD ; International Spine Study Group University-William Beaumont School of Medicine, Rochester, MI, 1Scripps Clinic Medical Group, Department of Orthopedics, La US 2 Jolla, CA, US; Hospital for Special Surgery, New York, NY, US; FDA Device/Drug Status: This abstract does not discuss or 3 4 Scripps Clinic, San Diego, CA, US; UC, Davis School of Medicine, include any applicable devices or drugs. Sacramento, CA, US; 5NY Spine Institute, NYU Langone Health, New York, NY, US; 6Department of Orthopaedic Surgery, NYU Langone Orthopaedic Hospital, NYU Langone Health, New York, P28. Are serum ion levels elevated in pediatric patients NY, US; 7University of Calgary, Calgary, Canada; 8Duke University with spinal implants versus controls? 9 , Durham, NC, US; UVA Health System, Charlottesville, VA, US; Smitha Mathew, MD1; Annalise N. Larson, MD1; Yong Xie, MD1; 10 11 Denver, CO, US; Johns Hopkins University, Baltimore, MD, US; Todd Milbrandt1; Matthew P. Abdel, MD1; Andre van Wijnen, MD1; 12 Washington University School of Medicine, St. Louis, MO, US; Geoffrey Haft, MD2 13Southwest Scoliosis Institute, Dallas, TX, US; 14Brighton, CO, US 1Mayo Clinic, Rochester, MN, US; 2Sanford USD Medical Center, FDA Device/Drug Status: This abstract does not discuss or Sioux Falls, SD include any applicable devices or drugs. FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. P24. Acute failure of S2-alar-iliac pelvic fixation following adult deformity correction P29. Predicting tumor specific survival in patients with Christopher T. Martin, MD1; David W. Polly Jr., MD1; Kenneth metastatic renal cell carcinoma: which scoring system is Holton, MD1; Jose San Miguel, MD, PhD1; Melissa Albersheim, most accurate? MD1; Jonathan N. Sembrano, MD1; Kristen E. Jones, MD1,2 Elie Massaad, MD1; Ali Kiapour, PhD1; Muhamed Hadzipasic, MD, 1 The Department of Orthopaedic Surgery, University of PhD2; John H. Shin, MD2 2 Minnesota, Minneapolis, MN, US; The Department of 1 2 Neurosurgery, University of Minnesota, Minneapolis, MN, US Boston, MA, US; Massachusetts General Hospital, Boston, MA, US FDA Device/Drug Status: S2AI Screws (Approved for this indication), thoracolumbosacral pedicle screw system (Approved FDA Device/Drug Status: This abstract does not discuss or for this indication) include any applicable devices or drugs.

P25. Association of preoperative hemoglobin A1c and P30. Safe and improved spinal surgery using a new device body mass index with wound infection rate in spinal in multiple indications surgery John H. Peloza, MD1; Michael Millgram, MD2; Larry T. Khoo, MD3; 4 5 1 1 Hani Malone, MD ; Richard D. Guyer, MD ; Jean-Charles Le Huec, Miner Ross, MD, MPH ; Sudarshan Iyer, BS ; Kenneth R. Gundle, 6 7 MD2,3; Donald A. Ross, MD1,2 MD, PhD ; Ely Ashkenazi, MD 1 2 1 Center for Spine Care, Dallas, TX, US; Israel Spine Center, Tel Department of Neurological Surgery, Oregon Health and Science 3 4 2 Aviv, Israel; Los Angeles, CA, US; Scripps Clinic, La Jolla, CA, US; University, Portland, Oregon, US; Operative Care Division, 5 3 Center for Disc Replacement at Texas Back Institute, Plano, TX, Portland Veterans Administration, Portland, OR, US; Department 6 7 of Orthopaedics and Rehabilitation, Oregon Health and Science US; Bordeaux, France; Tel Aviv, Israel University Portland, OR, US FDA Device/Drug Status: Dreal (Carevature Medical Ltd.) FDA Device/Drug Status: This abstract does not discuss or (Approved for this indication) include any applicable devices or drugs. P31. Lateral interface pressures during a spinal procedure: P26. Closed drainage versus non-drainage for single-level can we optimize positioning? lumbar discectomy: a prospective randomized controlled Daniel Refai, MD1; Eric Leung, BA2; Olumide Aruwajoye3; Richard study A. Hynes, MD4; Russ P. Nockels, MD5; Ronald A. Lehman Jr., MD6 Biao Wang, MD1; Lingbo Kong, MD, PhD2; Dingjun Hao, MD3 1Emory Orthopaedics & Spine Center, Atlanta, GA, US; 2The 3 1 2 3 Spine Hospital, New York, NY, US; Medtronic, Minneapolis, MN, Honghui Hospital, Xi’an, Shaanxi, China; Xi’an, China; Xi’an 4 5 Honghui Hospital, Xi’an, Shaanxi, China US; The B.A.C.K. Center, , FL, US; Loyola University Medical Center, Maywood, Il, US; 6The Spine Hospital, Columbia FDA Device/Drug Status: This abstract does not discuss or University/New York Presbyterian, New York, NY, US include any applicable devices or drugs. FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. Abstracts 95

P32. Trends in robotic spine surgery: a six-year analysis of P36. Operative time and learning curve between morbidity and mortality conventional fluoroscopy, fluoroscopy-based instrument Peter G. Passias, MD1; Avery Brown, BS2; Katherine E. Pierce, BS3; navigation, and robot-assisted instrumentation in Waleed Ahmad4; Sara Naessig, BS5; Bassel G. Diebo, MD6 minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) 1NY Spine Institute, NYU Langone Health, New York, NY, US; 1 2 3 2Department of Orthopedic Surgery, NYU Langone Orthopedic Timothy Wang, MD ; Farah Hamouda, BS ; Eric W. Sankey ; C. 4 4 Hospital, NYU Langone Health, New York, NY, US; 3NYU Spine Rory Goodwin, MD, PhD ; Isaac O. Karikari, MD ; Muhammad Abd- 5 Research Lab, New York, NY, US; 4New York, NY, US; 5NYU El-Barr, MD, PhD Langone Hospital, New York NY, US; 6Department of Orthopaedic 1Duke University, Durham, NC, US; 2Chapel Hill, NC, US; 3Duke Surgery, SUNY Downstate Medical Center, Brooklyn, NY, US University Hospital, Durham, NC, US; 4Duke University Medical 5 FDA Device/Drug Status: This abstract does not discuss or Center, Durham, NC, US; Duke Spine Center, Durham, NC, US include any applicable devices or drugs. FDA Device/Drug Status: TrackX (Approved for this indication)

P33. Complication rates following chiari malformation P37. Artificial intelligence clustering of adult spinal surgical management for Arnold-Chiari type I based on deformity morphology predicts surgical characteristics, surgical variables: a national perspective alignment, and outcomes Peter G. Passias, MD1; Waleed Ahmad2; Katherine E. Pierce, BS3; Wesley M. Durand1; Renaud Lafage, MSc2; D. Kojo Hamilton, Muhammad B. Janjua, MD4; Shaleen N. Vira, MD5; Bassel G. MD3; Peter G. Passias, MD4; Han Jo Kim, MD2; Themistocles S. Diebo, MD6 Protopsaltis, MD5; Virginie Lafage, PhD2; Justin S. Smith, MD, 6 7 8 1NY Spine Institute, NYU Langone Health, New York, NY, US; 2New PhD ; Christopher I. Shaffrey, MD ; Munish C. Gupta, MD ; Eric 9 2 10 York, NY, US; 3NYU Spine Research Lab, New York, NY, US; 4Mercy O. Klineberg, MD ; Frank J. Schwab, MD ; Jeffrey L. Gum, MD ; 11 12 Health, Rockford, IL, US; 5Department of Orthopaedic Surgery, Gregory M. Mundis Jr., MD ; Robert K. Eastlack, MD ; Khaled 13 14 UT Southwestern Medical Center, Dallas, TX, US; 6Department of M. Kebaish, MD ; Alexandra Soroceanu, MD, MPH ; Richard 15 16 17 Orthopaedic Surgery, SUNY Downstate Medical Center, Brooklyn, A. Hostin Jr., MD ; Douglas C. Burton, MD ; Shay Bess, MD ; 18 19 NY, US Christopher P. Ames, MD ; Robert A. Hart, MD ; Alan H. Daniels, MD20; International Spine Study Group21 FDA Device/Drug Status: This abstract does not discuss or 1 include any applicable devices or drugs. Brown University, Alpert Medical School, Providence, RI, US; 2Hospital for Special Surgery, New York, NY, US; 3University of Pittsburgh School of Medicine, Pittsburgh, PA, US; 4NY Spine P34. Evaluating the impact of multiple sclerosis on two Institute, NYU Langone Health, New York, NY, US; 5Department year postoperative outcomes following ACDF for cervical of Orthopaedic Surgery, NYU Langone Orthopaedic Hospital, degenerative pathology: a propensity score-matched NYU Langone Health, New York, NY, US; 6UVA Health System, analysis Charlottesville, VA, US; 7Duke University , Durham, NC, US; 8 Neil V. Shah, MD, MS1; George A. Beyer, MS2; Mahee Islam2; Pelin Washington University School of Medicine, St. Louis, MO, US; 9 10 Celiker, BS2; Frank A. Segreto, BS3; Renaud Lafage, MSc4; Peter G. UC, Davis School of Medicine, Sacramento, CA, US; Norton 11 Passias, MD5; Frank J. Schwab, MD4; Virginie Lafage, PhD4; Carl B. Leatherman Spine Center, Louisville, KY, US; Scripps Clinic Paulino, MD2; Bassel G. Diebo, MD1 Medical Group, Department of Orthopedics, La Jolla, CA, US; 12 13 1 Scripps Clinic, San Diego, CA, US; Johns Hopkins University, Department of Orthopaedic Surgery, SUNY Downstate Medical 14 2 Baltimore, MD, US; University of Calgary, Calgary, Canada; Center, Brooklyn, NY, US; SUNY Downstate Medical Center, 15 16 3 Southwest Scoliosis Institute, Dallas, TX, US; University of Brooklyn, NY, US; NYU Langone Medical Center - Orthopaedic 17 4 Kansas Medical Center, Kansas City, KS, US; Denver, CO, US; Hospital, Manhattan, NY, US; Hospital for Special Surgery, New 18 5 University of California, San Francisco, San Francisco, CA, US; York, NY, US; NY Spine Institute, NYU Langone Health, New York, 19Swedish Neuroscience Institute, Seattle, WA, US; 20Warren NY, US Alpert Medical School of BU/RI Hospital, Providence, RI, US; FDA Device/Drug Status: This abstract does not discuss or 21Brighton, CO, US include any applicable devices or drugs. FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs.

Diagnostics/Imaging ePosters P38. Spondylolysis in athletic children, how many hours of training a week is too much? P35. Quantitative romberg using a force plate: an objective measure for cervical myelopathy Karen Weissmann, MD1; Virginie Lafage, PhD2; Renaud Lafage, MSc2; David Seguel, MD3; Evangelia M. Zgonis, BS2; Tianna Jeffrey L. Gum, MD1; Steven D. Glassman, MD1; Morgan Brown, Bennett, BS4; Monica Chacon, PhD5 MS2; Christy L. Daniels, MS1; Joseph L. Laratta, MD1; Leah Y. Carreon, MD, MSc1 1Fundacion Medica San Cristobal, Santiago, Region Metropolitana, Chile; 2Hospital for Special Surgery, New York, 1Norton Leatherman Spine Center, Louisville, KY, US; 2Norton NY, US; 3Instituto Traumatologico de Chile, Santiago, Chile; 4New Healthcare, Louisville, KY, US York, NY, US; 5Hospital San Juan De Dios - Caja Costarricense Del FDA Device/Drug Status: This abstract does not discuss or Seguro Social, San Jose, Costa Rica include any applicable devices or drugs. FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. Abstracts 96

P39. Spinal epidural abscesses: can we predict treatment P43. Validity of routine diagnostic tests for vertebral modalities? osteomyelitis/discitis and its influence by the infecting Keith W. Lyons, MD; Steven Baltic, MD, MS1; Matthew Pappas, organism BS, BA1; Janae Dunchack, BA, MS2; Paul Werth, MS1; Kevin J. Michael Ghassibi, DO; Tzu Chuan Yen, MD1; Shelby M. Harris, BS2; McGuire, MD1; Adam M. Pearson, MD, MS1; William Abdu, MD1 Emily Leary, PhD3; Theodore J. Choma, MD3 1Dartnouth-Hitchcock Medical Center, Lebanon, NH, US; 1Missouri Orthopedic Institute, Columbia, MO, US; 2Columbia, MO, 4Dartmouth College, Hanover, NH, US US; 3Missouri Spine Center, Columbia, MO, US FDA Device/Drug Status: This abstract does not discuss or FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. include any applicable devices or drugs.

P40. Automated measurement of spinopelvic parameters P44. Computed tomography hounsfield units accurately on lateral lumbar radiographs using deep learning estimate the severity of cervical paraspinal muscle fat John T. Schwartz, BS1; Varun Arvind, MD, PhD1; Aly Valliani, BS2; infiltration Brian Cho, BS1; Eric Geng, BA1; Jun S. Kim, MD2; Samuel K. Cho, Ashley Xiong, CCRC 2 MD Mayo Clinic, Rochester, MN, US 1 Icahn School of Medicine at Mount Sinai, New York, NY, US; FDA Device/Drug Status: This abstract does not discuss or 2 New York, NY, US include any applicable devices or drugs. FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. P45. Radiological features of slip progression in adult patients with isthmic spondylolisthesis P41. Flexion-extension radiographs underestimate Fumitake Tezuka, MD, PhD1; Jonathan Paul, MPH, BS2; Koichi instability in patients with single-level lumbar Sairyo, MD1; Alpesh A. Patel, MD, FACS3; Wellington K. Hsu, MD4 spondylolisthesis. Comparing flexion-supine imaging 1 2 may be more appropriate Tokushima University, Tokushima, Japan; Chicago, IL, US; 3Northwestern Department of Orthopaedics, Chicago, IL, US; 1 2 Nathan J. Lee, MD ; Jun S. Kim, MD ; Joseph M. Lombardi, 4Northwestern University School of Medicine, Northwestern 3 2 4 MD ; Andrew C. Vivas, MD ; Jay S. Reidler, MD, MPH ; Scott L. University, Chicago, IL, US Zuckerman, MD9; Paul Park, MD2; Eric Leung, BA5; Meghan Cerpa, MPH6; Lawrence G. Lenke, MD3; Ronald A. Lehman Jr., MD7; FDA Device/Drug Status: This abstract does not discuss or Zeeshan Sardar, MD, MSc8 include any applicable devices or drugs. 1Columbia University, New York, NY, US; 2New York, NY, US; 3Columbia University Department of Orthopaedic Surgery, New York, NY, US; 4Johns Hopkins Hospital, Baltimore, MD, US; Epidemiology/Etiology ePosters 5The Spine Hospital, New York, NY, US; 6Columbia University Medical Center, New York, NY, US; 7The Spine Hospital -Columbia P46. Do diabetics experience more cervical spine University /New York Presbyterian, New York, NY, US; 8NewYork- degenerative disc disease Presbyterian The Allen Hospital, New York, NY, US; 9Jane Och Mark Lambrechts, MD1; Wyatt Whitman, BS2; Kyle Maryan, Spine Hospital, New York-Presbyterian/Allen Hospita, Columbia BS3; Tzu Chuan Yen, MD1; Jinpu Li, MA4; Suryanshi Rawat, BS1; University Medical Center, New York, NY, US Casey A. Fogarty1; Emily Leary, PhD5; Christina L. Goldstein, MD, FDA Device/Drug Status: This abstract does not discuss or FRCSC6; Theodore J. Choma, MD7 include any applicable devices or drugs. 1Missouri Orthopaedic Institute, Columbia, MO, US; 2University Hospital-University of Missouri, Columbia, MO, US; 3University 4 P42. When does MRI change management of pediatric of Missouri School of Medicine, Columbia, MO, US; School of back pain? A predictive scoring system Medicine, University of Missouri – Columbia, Columbia, MO, US; 5Columbia, MO, US; 6UCHealth Memorial Hospital North Spine 1 2 3 Michael T. Nolte, MD ; Garrett Harada, MD ; Ryan LeDuc ; Bryce Center, Colorado Springs, US; 7Missouri Spine Center, Columbia, 4 5 6 Basques, MD, MHS ; Philip Louie, MD ; Ethan Gordon, MS ; MO, US Monica Kogan, MD3; Dino Samartzis, ScD, PhD, MSc7; Howard S. An, MD8 FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. 1Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, US; 2Los Angeles, CA, US; 3Chicago, IL, US; 4Thomas Jefferson University, Philadelphia, PA, US; 5New York, P47. The association of patient frailty increased NY, US; 6Midwestern Orthopedics at Rush, Chicago, IL, US; 7Queen complication and readmission rates after lumbar spinal Mary Hospital, Hong Kong, Hong Kong; 8Rush University Medical fusion surgery Center, Department of Orthopedic Surgery, Chicago, IL, US Shane Shahrestani, MS1; Andy Ton, BS2; Xiao Chen, BA3; Alexander FDA Device/Drug Status: This abstract does not discuss or Ballatori, BA3; Jeffrey C. Wang, MD4; Zorica Buser, PhD5 include any applicable devices or drugs. 1Yorba Linda, CA, US; 2Anaheim, CA, US; 3Los Angeles, CA, US; 4USC Spine Center, Los Angeles, CA, US; 5Keck School of Medicine, University of Southern California, Los Angeles, CA, US FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. Abstracts 97

P48. Disparities in etiology, clinical presentation and P51. The effect of structural spinal deformities on the determinants for distal junctional kyphosis based on effectiveness of spinal cord stimulators timing of occurrence: are we treating two separate Ajith Malige, MD; Andrew Kantzos, MD; Gbolabo O. Sokunbi, MD issues? St. Luke’s University Health Network, Bethlehem, PA, US Katherine E. Pierce, BS1; Peter G. Passias, MD2; Virginie Lafage, PhD3; Renaud Lafage, MSc3; Han Jo Kim, MD3; Alan H. Daniels, FDA Device/Drug Status: This abstract does not discuss or MD4; Robert K. Eastlack, MD5; Eric O. Klineberg, MD6; Breton Line, include any applicable devices or drugs. BS7; Themistocles S. Protopsaltis, MD8; Douglas C. Burton, MD9; Shay Bess, MD10; Frank J. Schwab, MD3; Christopher I. Shaffrey, P52. Trends in usage of navigation-assisted and robotic MD11; Justin S. Smith, MD, PhD12; Christopher P. Ames, MD13; in elective spine surgeries: a study of 105,212 cases from International Spine Study Group14 2007 to 2016 1 2 NYU Spine Research Lab, New York, NY, US; NY Spine Institute, Sara Naessig, BS1; Waleed Ahmad2; Katherine E. Pierce, BS3; 3 NYU Langone Health, New York, NY, US; Hospital for Special Shaleen N. Vira, MD4; Bassel G. Diebo, MD5; Peter G. Passias, MD6 4 Surgery, New York, NY, US; Warren Alpert Medical School of BU/ 1 2 5 NYU Langone Hospital, New York NY, US; New York, NY, US; RI Hospital, Providence, RI, US; Scripps Clinic, San Diego, CA, 3 4 US; 6UC, Davis School of Medicine, Sacramento, CA, US; 7Denver NYU Spine Research Lab, New York, NY, US; Department of International Spine Center, Denver, CO, US; 8Department of Orthopaedic Surgery, UT Southwestern Medical Center, Dallas, TX, US; 5Department of Orthopaedic Surgery, SUNY Downstate Orthopaedic Surgery, NYU Langone Orthopaedic Hospital, NYU 6 Langone Health, New York, NY, US; 9University of Kansas Medical Medical Center, Brooklyn, NY, US; NY Spine Institute, NYU Center, Kansas City, KS, US; 10Denver, CO, US; 11Duke University Langone Health, New York, NY, US , Durham, NC, US; 12UVA Health System, Charlottesville, VA, US; FDA Device/Drug Status: This abstract does not discuss or 13University of California, San Francisco, San Francisco, CA, US; include any applicable devices or drugs. 14Brighton, CO, US FDA Device/Drug Status: This abstract does not discuss or P53. Allogeneic disc matrix as treatment for disc include any applicable devices or drugs. degeneration: improvement in pain and function at 1- and 2-levels Douglas P. Beall, MD Exercise ePosters Clinical Radiology of Oklahoma, Edmond, OK, US P49. Physical activity measures in lumbar laminectomy FDA Device/Drug Status: This abstract does not discuss or patients: a prospective comparison of fitness tracker include any applicable devices or drugs. measures versus patient-reported outcome measures Dennis M. Bienstock, BS1; Dhruv S. Shankar, BS2; Jinseong Kim, BS1; Nicole Zubizarreta, MPH2; Jashvant Poeran, MD, PhD1; Interdisciplinary Care ePosters Wesley H. Bronson, MD, MS3; Saad B. Chaudhary, MD, MBA4; James C. Iatridis, PhD2 P54. Multimodal pain control regimen for anterior lumbar fusion drastically reduces in-hospital opioid consumption 1New York, NY, US; 2Icahn School of Medicine at Mount Sinai, New York, NY, US; 3The Spine Center at Mount Sinai, New York, Jeffrey L. Gum, MD1; Portia Steele, ACNP-BC1; Charles H. NY, US; 4Mount Sinai Health System, New York, NY, US Crawford III, MD1; Mladen Djurasovic, MD1; R. Kirk Owens II, MD1; Morgan Brown, MS2; Christy L. Daniels, MS1; Benjamin M. FDA Device/Drug Status: This abstract does not discuss or Sampedro, CRNA, BSN, BS3; John R. Dimar II , MD1; Steven D. include any applicable devices or drugs. Glassman, MD1; Leah Y. Carreon, MD, MSc1 1Norton Leatherman Spine Center, Louisville, KY, US; 2Norton 3 Injections/Interventions ePosters Healthcare, Louisville, KY, US; Norton Hospital, Louisville, KY, US FDA Device/Drug Status: This abstract does not discuss or P50. Effect of systemic teriparatide (PTH1-34) versus include any applicable devices or drugs. placebo on bone mineral density (BMD) after lumbar spinal arthrodesis P55. What is the value of undergoing surgery for spinal Astrid Gimbel, BHSc1; Mikkel Andersen, MD2; Annette metastases at dedicated cancer centers? 3 Bennedsgaard Jespersen, MD, PhD ; Anne Pernille Hermann, MD, Azeem T. Malik, MBBS1; Safdar N. Khan, MD1; John Alexander, 4 5 PhD ; Leah Y. Carreon, MD, MSc MD1; Ryan Voskuil, MD2; Joseph Drain, MD2; Tom J. 1Odense, Denmark; 2Middelfart, Denmark; 3Spine Center Region Scharschmidt, MD3 4 of Southern Denmark, Middlefart, Denmark; Odense University 1The Ohio State University Wexner Medical Center, Columbus, 5 Hospital, Odense C, Denmark; Sygehus Lillebælt - Rygkirurgi OH, US; 2Columbus, OH, US; 3The Ohio State University Medical Middelfart, Denmark Center, Columbus, OH, US FDA Device/Drug Status: This abstract does not discuss or FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. include any applicable devices or drugs. Abstracts 98

P56. A multidisciplinary spine clinic model significantly P59. Chronic preoperative opioid use is associated with reduces spine surgery utilization higher perioperative resource utilization and adverse Joshua Benton, BA1; Brandon Weiss, BS2; Michael Longo, BA3; outcomes in adult spinal deformity patients Wenzhu Mowrey, PhD1; Rafael De la Garza Ramos, MD4; Yaroslav Ibrahim Sadiq, MD1; Faizal Kassam, MD, FRCSC2; Ariana J. Gelfand, MD5; Phillip Cezayirli, MD6; Erida Castro-Rivas, MS3; Frederick, MS3; Fred Nicholls, MD, MA, FRCSC3; Peter D. Mark Headlam, BS3; Lavinia Williams, RN7; Adaobi Udemba, Lewkonia, MD4; Bradley Jacobs, MD, FRCSC5; Ganesh Swamy, ACNP-BC4; Reza Yassari, MD, MSc5; Vijay Yanamadala, MD5 MD2; Alexandra Soroceanu, MD, MPH6 1Albert Einstein College of Medicine, Bronx, NY, US; 2Montefiore 1Calgary, AB, Canada; 2Foothills Medical Centre, Calgary, AB, Department of Neurosurgery, Bronx, NY, US; 3Bronx, NY, US; Canada; 3University of Calgary, Calgary, AB, Canada; 4Caleo 4Montefiore Medical Center, Department of Neurosurgery, Spine Health, Calgary, AB, Canada; 5University of Calgary, Foothills Research Group, Bronx, NY, US; 5Montefiore Medical Center, Hospital, Calgary, AB, Canada; 6University of Calgary, Calgary, Bronx, NY, US; 6Albert Einstein College of Medicine/Montefiore Canada 7 Medical Center, Bronx, NY, US; Montefiore, Bronx, NY, US FDA Device/Drug Status: This abstract does not discuss or FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. include any applicable devices or drugs. P60. The top 100 spine surgery articles on social media: P57. ERAS vs non-ERAS: protocol implementation an altmetric study resulted in significant outcomes improvement in patients James Parrish, MPH1; Nathaniel Jenkins, BS, MS1; Nadia undergoing lumbar spine fusion Hrynewycz, BS2; Thomas Brundage, BS3; Kern Singh, MD1 1 1 Richard W. Easton, MD ; Nicholas S. Papakonstantinou, MD ; 1Rush University Medical Center, Chicago, IL, US; 2Chicago, IL, US; 2 3 1 Kevin Baker, PhD ; Erin A. Baker, MS ; Brady Vibert, MD ; Matthew 3Midwest Orthopedics at Rush, Chicago, IL, US Lipphardt, MD2; Bradley Ahlgren, MD1; Cecile Pestano, RN, BSN, CCRP1; Christopher A. Hulen, MD1; Daniel Silvasi, MD4; Gregory FDA Device/Drug Status: This abstract does not discuss or Smith, MD4 include any applicable devices or drugs. 1Michigan Orthopaedic & Spine Surgeons, Rochester Hills, MI, US; 2Beaumont Health, Royal Oak, MI, US; 3William Beaumont P61. A significant number of elective spine surgery plans Hospital/Research Institute, Royal Oak, MI, US; 4Beaumont are altered by a weekly indications conference with high Health, Troy, MI, US surgeon compliance FDA Device/Drug Status: Hydromorphone (Approved for this Joshua Benton, BA1; Rafael De la Garza Ramos, MD2; Yaroslav indication), Methadone HCl (Approved for this indication), J. Gelfand, MD3; Erida Castro-Rivas, MS4; Mark Headlam, BS4; Tranexamic Acid (Approved for this indication), Patient-Controlled Lavinia Williams, RN5; Adaobi Udemba, ACNP-BC3; Reza Yassari, Analgesia (PCA) Pump (Approved for this indication) MD, MSc3; Vijay Yanamadala, MD6 1Albert Einstein College of Medicine, Bronx, NY, US; 2Montefiore P58. The inherent value of preoperative optimization: Medical Center, Department of Neurosurgery, Spine Research 3 absolute and incremental reduction in components of Group, Bronx, NY, US; Montefiore Medical Center, Bronx, NY, US; 4 5 6 metabolic syndrome can enhance recovery and minimize Bronx, NY, US; Montefiore, Bronx, NY, US; Stamford, CT, US perioperative burden. FDA Device/Drug Status: This abstract does not discuss or Sara Naessig, BS1; Waleed Ahmad2; Katherine E. Pierce, BS3; include any applicable devices or drugs. Ethan W. Ayres, MPH4; Shaleen N. Vira, MD5; Peter G. Passias, MD6 1NYU Langone Hospital, New York NY, US; 2New York, NY, US; Motion Preservation ePosters 3NYU Spine Research Lab, New York, NY, US; 4Department of Orthopedic Surgery, NYU Langone Orthopedic Hospital, NYU P62. Removed from Program Langone Health, New York, NY, US; 5Department of Orthopaedic 6 Surgery, UT Southwestern Medical Center, Dallas, TX, US; NY P63. Current incidence of adjacent segment pathology Spine Institute, NYU Langone Health, New York, NY, US following lumbar fusion versus motion preserving FDA Device/Drug Status: This abstract does not discuss or procedures: a systematic review and meta-analysis of include any applicable devices or drugs. recent projections Chester J. Donnally III, MD1; Parthik Patel, MD1; Harsh Shah, MD2; Jose A. Canseco, MD, PhD3; Srikanth Divi, MD; Vadim Goz, MD5; Kartik Shenoy, MD6; Alexander R. Vaccaro, MD, PhD6 1Philadelphia, PA, US; 2Department of Orthopaedic Surgery, Miami, FL, US; 3Rothman Institute/Thomas Jefferson University Hospital, Philadelphia, PA, US; 5Rothman Institute, Philadelphia, PA, US; 6Department of Orthopedic Surgery, NYU Langone Orthopedic Hospital, NYU Langone Health, New York, NY, US FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. Abstracts 99

P64. In which cases do surgeons specializing in total disc Socio-Economics/Industrial/Ergonomic replacement perform fusion in patients with symptomatic lumbar disc degeneration? ePosters Jack E. Zigler, MD1; Donna D. Ohnmeiss, PhD2; Scott L. P68. The impact of spine surgeon training, office wait Blumenthal, MD1; Richard D. Guyer, MD1; Alexander M. Satin, MD2 times, and social media presence on physician review 1Center for Disc Replacement at Texas Back Institute, Plano, TX, websites US; 3Texas Back Institute Research Foundation, Plano, TX, US Andrew Sama, BA1; Nicholas Schiller, MSc2; Johnathon R. FDA Device/Drug Status: This abstract does not discuss or McCormick, BS3; Kevin Bondar, BA4; Deborah J. Li, BA1; Jose A. include any applicable devices or drugs. Canseco, MD, PhD5; Chester J. Donnally III, MD6 1Miami, FL, US; 2University of Miami, Miami, FL, US; 3University of P65. Total disc replacement as a part of adult scoliosis Miami Miller School of Medicine, Miami, FL, US; 4Miller School of surgical treatment of 205 patients with minimum of two Medicine, Miami, FL, US; 5Rothman Institute/Thomas Jefferson years of follow-up University Hospital, Philadelphia, PA, US; 6Philadelphia, PA, US Thierry P. Marnay, MD FDA Device/Drug Status: This abstract does not discuss or Castelnau-le-Lez, France include any applicable devices or drugs. FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. P69. Social media accessibility, shorter office wait times, and review website personalization are correlated with better online review scores for spine surgeons Psychosocial/Behavioral ePosters Chester J. Donnally III, MD1; Johnathon R. McCormick, BS2; Mark Pastore, DO3; Andrew Sama, BA4; Nicholas Schiller, MSc5; 4 6 7 P66. Disagreement between patients’ and surgeons’ Deborah J. Li, BA ; Kevin Bondar, BA ; Kartik Shenoy, MD ; 8 8 expectations for outcomes of lumbar surgery according to Christopher K. Kepler, MD, MBA ; Alexander R. Vaccaro, MD, PhD domains of physical and mental health 1Philadelphia , PA, US; 2University of Miami Miller School of 3 Roland Duculan, MD; Frank P. Cammisa, MD; Andrew A. Sama, Medicine, Miami, FL, US; Philadelphia College of Osteopathic 4 5 MD; Alexander P. Hughes, MD; Darren R. Lebl, MD; Carol A. Medicine, Philadelphia, PA, US; Miami, FL, US; University of 6 Mancuso, MD; Federico P. Girardi, MD Miami, Miami , FL, US; Miller School of Medicine, Miami, FL, US; 7Department of Orthopedic Surgery, NYU Langone Orthopedic Hospital for Special Surgery, New York, NY, US Hospital, NYU Langone Health, New York, NY, US; 8Rothman FDA Device/Drug Status: This abstract does not discuss or Institute, Philadelphia, PA, US include any applicable devices or drugs. FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. P67. Effects cognitive behavioral therapy on cervical spine surgery: results of a randomized controlled trial P70. A combined anterior-posterior approach in select Peter G. Passias, MD1; Sara Naessig, BS2; Waleed Ahmad3; cervical deformity corrections has potential for superior Katherine E. Pierce, BS4; Brooke K. O’Connell, MS3; Constance cost effectiveness driven by outcomes 3 5 Maglaras, PhD ; Bassel G. Diebo, MD Katherine E. Pierce, BS1; Peter G. Passias, MD2; Renaud Lafage, 1NY Spine Institute, NYU Langone Health, New York, NY, US; MSc3; Virginie Lafage, PhD3; Gregory M. Mundis Jr., MD4; 2NYU Langone Hospital, New York NY, US; 3New York, NY, US; Robert K. Eastlack, MD5; Michael P. Kelly, MD; Themistocles S. 4NYU Spine Research Lab, New York, NY, US; 5Department of Protopsaltis, MD6; Leah Y. Carreon, MD, MSc7; Breton Line, BS8; Orthopaedic Surgery, SUNY Downstate Medical Center, Brooklyn, Robert A. Hart, MD9; Douglas C. Burton, MD10; Shay Bess, MD11; NY, US Frank J. Schwab, MD3; Christopher I. Shaffrey, MD12; Justin S. Smith, MD, PhD13; Christopher P. Ames, MD14; International Spine FDA Device/Drug Status: This abstract does not discuss or Study Group15 include any applicable devices or drugs. 1NYU Spine Research Lab, New York, NY, US; 2NY Spine Institute, NYU Langone Health, New York, NY, US; 3Hospital for Special Surgery, New York, NY, US; 4Scripps Clinic Medical Group, Department of Orthopedics, La Jolla, CA, US; 5Scripps Clinic, San Diego, CA, US; 6Department of Orthopaedic Surgery, NYU Langone Orthopaedic Hospital, NYU Langone Health, New York, NY, US; 7Norton Leatherman Spine Center, Louisville, KY, US; 8Denver International Spine Center, Denver, CO, US; 9Swedish Neuroscience Institute, Seattle, WA, US; 10University of Kansas Medical Center, Kansas City, KS, US; 11Denver, CO, US; 12Duke University, Durham, NC, US; 13UVA Health System, Charlottesville, VA, US; 14University of California, San Francisco, San Francisco, CA, US; 15Brighton, CO, US FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. Abstracts 100

P71. When not to operate in spinal deformity: identifying P74. Adult spinal deformity patients with metabolic subsets of patients with simultaneous clinical syndrome have significantly higher costs deterioration, major complications, and reoperation Hamid Hassanzadeh, MD5; Lawal Labaran6; Themistocles S. Peter G. Passias, MD1; Katherine E. Pierce, BS2; Renaud Lafage, Protopsaltis, MD2; Aaron J. Buckland, MBBS, FRACS2 3 3 4 MSc ; Virginie Lafage, PhD ; D. Kojo Hamilton, MD ; Gregory M. 1NY Spine Institute, NYU Langone Health, New York, NY, US; 5 3 6 Mundis Jr., MD ; Han Jo Kim, MD ; Richard A. Hostin Jr., MD ; 2Department of Orthopedic Surgery, NYU Langone Orthopedic 7 8 Alan H. Daniels, MD ; Robert A. Hart, MD ; Douglas C. Burton, Hospital, NYU Langone Health, New York, NY, US; 3NYU Spine 9 10 3 MD ; Christopher I. Shaffrey, MD ; Frank J. Schwab, MD ; Research Lab, New York, NY, US; 4New York, NY, US; 5University 11 12 Christopher P. Ames, MD ; Justin S. Smith, MD, PhD ; Shay Bess, of Virginia, Department of Orthopedic Surgery, Charlottesville, VA, 13 14 15 MD ; Eric O. Klineberg, MD ; International Spine Study Group US; 6Richton Park, IL, US 1 NY Spine Institute, NYU Langone Health, New York, NY, US; FDA Device/Drug Status: This abstract does not discuss or 2 3 NYU Spine Research Lab, New York, NY, US; Hospital for include any applicable devices or drugs. Special Surgery, New York, NY, US; 4University of Pittsburgh School of Medicine, Pittsburgh, PA, US; 5Scripps Clinic Medical Group, Department of Orthopedics, La Jolla, CA, US; 6Southwest P75. Average costs, length of stay, and 30- and 90-day Scoliosis Institute, Dallas, TX, US; 7Warren Alpert Medical School readmissions in obese and morbidly obese patients who of BU/RI Hospital, Providence, RI, US; 8Swedish Neuroscience undergo lumbar spine fusion 9 Institute, Seattle, WA, US; University of Kansas Medical Xiao Chen, BA1; Shane Shahrestani, MS2; Andy Ton, BS3; Alexander 10 Center, Kansas City, KS, US; Duke University, Durham, NC, US; Ballatori, BA1; Jeffrey C. Wang, MD4; Zorica Buser, PhD5 11 University of California, San Francisco, San Francisco, CA, US; 1 2 3 12 13 Los Angeles, CA, US; Yorba Linda, CA, US; Anaheim, CA, UVA Health System, Charlottesville, VA, US; Denver, CO, US; 4 5 14UC, Davis School of Medicine, Sacramento, CA, US; 15Brighton, US; USC Spine Center, Los Angeles, CA, US; Keck School of CO, US Medicine, University of Southern California, Los Angeles, CA, US FDA Device/Drug Status: This abstract does not discuss or FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. include any applicable devices or drugs.

P72. Natural language processing of operative note P76. Economic impact of the initial incorporation of dictations to automatically generate CPT codes for billing robotics in spine surgery 1 2 3 1 2 2 Peter G. Passias, MD ; Avery Brown, BS ; Katherine E. Pierce, BS ; Jun S. Kim, MD ; Varun Arvind, MD, PhD ; John T. Schwartz, BS ; 4 5 6 1 3 4 Waleed Ahmad ; Sara Naessig, BS ; Shaleen N. Vira, MD ; Jordan Aly Valliani, BS ; Eric Geng, BA ; Nathan J. Lee, MD ; Joseph M. 7 8 Lombardi, MD5; Andrew C. Vivas, MD1; Jay S. Reidler, MD, MPH6; Lebovic, BA ; Bassel G. Diebo, MD Scott L. Zuckerman, MD8; Brian Cho, BS3; Meghana Vulapalli, BS7; 1NY Spine Institute, NYU Langone Health, New York, NY, US; Samuel K. Cho, MD6; Ronald A. Lehman Jr., MD8; Lawrence G. 2Department of Orthopedic Surgery, NYU Langone Orthopedic Lenke, MD5; K. Daniel Riew, MD Hospital, NYU Langone Health, New York, NY, US; 3NYU Spine 4 5 1 2 Research Lab, New York, NY, US; New York, NY, US; NYU New York, NY, US; Icahn School of Medicine at Mount Sinai, 6 New York, NY, US; 3Icahn School of Medicine, New York, NY, US; Langone Hospital, New York NY, US; Department of Orthopaedic 4 5 Surgery, UT Southwestern Medical Center, Dallas, TX, US; Columbia University, New York, NY, US; Columbia University 7 8 Department of Orthopaedic Surgery, New York, NY, US; 6Johns Scarsdale, NY, US; Department of Orthopaedic Surgery, SUNY Hopkins Hospital, Baltimore, MD, US; 7Columbia University Downstate Medical Center, Brooklyn, NY, US Medical Center, New York, NY, US; 8The Spine Hospital -Columbia FDA Device/Drug Status: This abstract does not discuss or University/New York Presbyterian, New York, NY, US include any applicable devices or drugs. FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. Spinal Deformity ePosters P73. Clinical review of spine surgery patient safety P77. Enhanced recovery after surgery reduces post- indicators avoids CMS payment reductions operative opioid use and 30-day readmission rates John A. Buza III, MD, MS1; Ryan Nazar, MD, MHA2; Portia Steele, after open thoracolumbar fusion for adult degenerative ACNP-BC3; Leah Y. Carreon, MD, MSc3; Joseph L. Laratta, MD4; scoliosis Steven D. Glassman, MD3; Jeffrey L. Gum, MD3 Emmanuel Adeyemo, BA1; Umaru Barrie, BS2; Salah Aoun, MD2; 1Department of Orthopedic Surgery, NYU Langone Orthopedic Olatunde Badejo, BA3; Mark N. Pernik, BA4; Zachary Christian, BA4; Hospital, NYU Langone Health, New York, NY, US; 2Norton Luke Dosselman, BS4; Kristen Hall, BS5; Carlos A. Bagley, MD6 Healthcare, Louisville, KY, US; 3Norton Leatherman Spine Center, 1UT Southwestern Medical Center, Dallas, TX, US; 2UTSW, Dallas, Louisville, KY, US; 4Norton Leatherman Spine, Louisville, KY, US TX, US; 3Dallas, TX, US; 4UT Southwestern, Dallas, TX, US; 5UT FDA Device/Drug Status: This abstract does not discuss or Southwestern Medical Center, Dallas, TX, US; 6University of Texas include any applicable devices or drugs. Southwestern Medical Center, Dallas, TX, US FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. Abstracts 101

P78. Spinopelvic sagittal imbalance as a risk factor for P81. Assessing methods to prevent pseudarthrosis in ASD fracture type of proximal junctional failure after posterior surgery of lesser magnitude instrumented fusion. Emmanuel McNeely, MS, MHA1; Brian J. Neuman, MD2; Rahul Jen-Chung Liao, MD Sachdev, BS2; Eric O. Klineberg, MD3; Justin S. Smith, MD, PhD4; 5 6 Chang Gung Memorial Hospital, Tao Yuan, Taiwan Gregory M. Mundis Jr., MD ; Alexandra Soroceanu, MD, MPH ; Richard A. Hostin Jr., MD7; Peter G. Passias, MD8; Themistocles FDA Device/Drug Status: This abstract does not discuss or S. Protopsaltis, MD9; D. Kojo Hamilton, MD10; Christopher P. Ames, include any applicable devices or drugs. MD11; Khaled M. Kebaish, MD12; International Spine Study Group13 1The Johns Hopkins Hospital, Baltimore, MD, US; 2Baltimore, MD, P79. Prevalence and surgical outcomes of primary severe US; 3UC, Davis School of Medicine, Sacramento, CA, US; 4UVA sagittal plane deformity (pSPD) in adult spinal deformity Health System, Charlottesville, VA, US; 5Scripps Clinic Medical (ASD) surgery: comparison between Japan and the United Group, Department of Orthopedics, La Jolla, CA, US; 6University States of Calgary, Calgary, Canada; 7Southwest Scoliosis Institute, 8 Mitsuru Yagi, MD, PhD1; Christopher P. Ames, MD2; Naobumi Dallas, TX, US; NY Spine Institute, NYU Langone Health, New 9 Hosogane, MD, PhD3; Justin S. Smith, MD, PhD4; Christopher York, NY, US; Department of Orthopaedic Surgery, NYU Langone I. Shaffrey, MD5; Frank J. Schwab, MD6; Virginie Lafage, PhD6; Orthopaedic Hospital, NYU Langone Health, New York, NY, US; 10 Morio Matsumoto, MD7; Shay Bess, MD8; Kota Watanabe, MD9; University of Pittsburgh School of Medicine, Pittsburgh, PA, US; 11 International Spine Study Group10 University of California, San Francisco, San Francisco, CA, US; 12Johns Hopkins University, Baltimore, MD, US; 13Brighton, CO, US 1Department of Orthopedic Surgery, Keio University School of Medicine, Tokyo, Japan; 2University of California, San Francisco, FDA Device/Drug Status: This abstract does not discuss or San Francisco, CA, US; 3Kyorin University, Mitaka, Tokyo, Japan; include any applicable devices or drugs. 4UVA Health System, Charlottesville, VA, US; 5Duke University, 6 Durham, NC, US; Hospital for Special Surgery, New York, NY, US; P82. A proper spinal column shortening in PVCR make a 7 8 Keio University School of Medicine, Tokyo, Japan; Denver, CO, better result US; 9Keio University, Keio, Japan; 10Brighton, CO, US Tao Li, MD1; Yingsong Wang, MD1; Jing-Ming Xie, MD1; Zhaoquan FDA Device/Drug Status: This abstract does not discuss or Zhang, MD2; Ying Zhang, MD1; Zhi Zhao, MD1; Ni Bi, MD1; Zhiyue include any applicable devices or drugs. Shi, MD1; Quan Li, MD1 1Department of Orthopaedics, 2nd Affiliated Hospital of Kunming P80. Demographic differences and health impact of Medical University, Kunming, China; 2Kunming, Yunnan, China severe global sagittal, coronal, and mixed spinal deformity FDA Device/Drug Status: This abstract does not discuss or in symptomatic adults include any applicable devices or drugs. Thomas Buell, MD1; Justin S. Smith, MD, PhD2; Christopher I. Shaffrey, MD3; Han Jo Kim, MD4; Eric O. Klineberg, MD5; Virginie Lafage, PhD4; Renaud Lafage, MSc4; Themistocles S. Protopsaltis, P83. Preoperative hounsfield units at the planned upper MD6; Peter G. Passias, MD7; Gregory M. Mundis Jr., MD8; Robert instrumented vertebrae (UIV) may predict proximal K. Eastlack, MD9; Vedat Deviren, MD10; Michael P. Kelly, MD; Alan junctional Kyphosis (PJK) in adult spinal deformity H. Daniels, MD11; Jeffrey L. Gum, MD12; Alexandra Soroceanu, Yu-Cheng Yao, MD1; Jonathan Elysee2; Michael H. McCarthy, MD, MD, MPH13; D. Kojo Hamilton, MD14; Munish C. Gupta, MD15; MPH; Philip Louie, MD3; Renaud Lafage, MSc2; Karen Weissmann, Douglas C. Burton, MD16; Richard A. Hostin Jr., MD17; Khaled M. MD4; Basel Sheikh Alshabab, MD2; Virginie Lafage, PhD2; Frank J. Kebaish, MD18; Robert A. Hart, MD19; Frank J. Schwab, MD4; Shay Schwab, MD2; Han Jo Kim, MD2 20 10 Bess, MD ; Christopher P. Ames, MD ; International Spine Study 1Taipei Veterans General Hospital, Taipei, Taiwan; 2Hospital for 21 Group Special Surgery, New York, NY, US; 3New York, NY, US; 4Fundacion 1University of Virginia Neurosurgery, Charlottesville , VA, US; Medica San Cristobal, Santiago, Region Metropolitana, Chile 2 3 UVA Health System, Charlottesville, VA, US; Duke University , FDA Device/Drug Status: This abstract does not discuss or 4 Durham, NC, US; Hospital for Special Surgery, New York, NY, US; include any applicable devices or drugs. 5UC, Davis School of Medicine, Sacramento, CA, US; 6Department of Orthopaedic Surgery, NYU Langone Orthopaedic Hospital, NYU Langone Health, New York, NY, US; 7NY Spine Institute, P84. Predictive model for selection of upper treated NYU Langone Health, New York, NY, US; 8Scripps Clinic Medical vertebra using a machine learning approach 9 Group, Department of Orthopedics, La Jolla, CA, US; Scripps Renaud Lafage, MSc1; Basel Sheikh Alshabab, MD1; Jonathan 10 Clinic, San Diego, CA, US; University of California, San Francisco, Elysee1; Francis C. Lovecchio, MD1; Karen Weissmann, MD2; Han 11 San Francisco, CA, US; Warren Alpert Medical School of BU/RI Jo Kim, MD1; Frank J. Schwab, MD1; Virginie Lafage, PhD1 12 Hospital, Providence, RI, US; Norton Leatherman Spine Center, 1 2 Louisville, KY, US; 13University of Calgary, Calgary, Canada; Hospital for Special Surgery, New York, NY, US; Fundacion 14University of Pittsburgh School of Medicine, Pittsburgh, PA, Medica San Cristobal, Santiago, Region Metropolitana, Chile US; 15Washington University School of Medicine, St. Louis, MO, FDA Device/Drug Status: This abstract does not discuss or US; 16University of Kansas Medical Center, Kansas City, KS, US; include any applicable devices or drugs. 17Southwest Scoliosis Institute, Dallas, TX, US; 18Johns Hopkins University, Baltimore, MD, US; 19Swedish Neuroscience Institute, Seattle, WA, US; 20Denver, CO, US; 21Brighton, CO, US FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. Abstracts 102

P85. Reducing delirium after complex spinal surgery (≥4 P89. Do readmissions and reoperations adversely affect levels): the UT Southwestern Perioperative Optimization patient-reported outcomes associated with complex of Senior Health Program adult spinal deformity surgery at a minimum two year Mark N. Pernik, BA1; Palvasha Deme, BA2; Madelina Nguyen3; postoperative? Salah Aoun, MD4; Owoicho Adogwa, MD, MPH5; Kristen Hall, BS6; Nathan J. Lee, MD1; Jun S. Kim, MD2; Andrew C. Vivas, MD2; Nickolas A. Stewart6; Luke Dosselman, BS3; Shelley McDonald, Joseph M. Lombardi, MD3; Jay S. Reidler, MD, MPH4; Scott L. DO, PhD7; Sarah Wingfield, MD6; Carlos A. Bagley, MD8 Zuckerman, MD8; Daniel Hong, MD2; Meghan Cerpa, MPH5; Eric 6 7 2 1UT Southwestern, Dallas, TX, US; 2UT Southwestern Medical Leung, BA ; Paul Park, MD ; Zeeshan Sardar, MD, MSc ; Ronald A. 8 3 School, Dallas, TX, US; 3Dallas, TX, US; 4UTSW, Dallas, TX, US; Lehman Jr., MD ; Lawrence G. Lenke, MD 5University of Texas Southwestern Medical School, Dallas, TX, US; 1Columbia University, New York, NY, US; 2New York, NY, US; 6UT Southwestern Medical Center, Dallas, TX, US; 7Duke, Durham, 3Columbia University Department of Orthopaedic Surgery, New NC, US; 8University of Texas Southwestern Medical Center, York, NY, US; 4Johns Hopkins Hospital, Baltimore, MD, US; Dallas, TX, US 5Columbia University Medical Center, New York, NY, US; 6The 7 FDA Device/Drug Status: This abstract does not discuss or Spine Hospital, New York, NY, US; NewYork-Presbyterian The 8 include any applicable devices or drugs. Allen Hospital, New York, NY, US; The Spine Hospital -Columbia University/New York Presbyterian, New York, NY, US FDA Device/Drug Status: This abstract does not discuss or P86. Postoperative bracing does not improve the rate of include any applicable devices or drugs. proximal junctional kyphosis in adult spinal deformity Stanley Crawford, DO1; Nina Lara, MD2; Jan Revella, RN3; John M. Popovich Jr., PhD, DPT, ATC4; Biodun Adeniyi, MBBS, MS5; Dennis P90. External validation of the ESSG-ISSG calculator G. Crandall, MD3; Michael S. Chang, MD3 utilizing a single institutional experience for adult spinal deformity corrective surgery 1Sonoran Spine Institute, Tempe, AZ, US; 2Mayo Clinic Phoenix, 1 2 3 Phoenix, AZ, US; 3Sonoran Spine Center, Tempe, AZ, US; 4MSU Peter G. Passias, MD ; Sara Naessig, BS ; Waleed Ahmad ; Bassel 4 3 5 Center for Orthopedic Research, Lansing, MI, US; 5Sonoran Spine, G. Diebo, MD ; Tina Raman, MD ; Virginie Lafage, PhD ; Renaud 5 6 Tempe, AZ, US Lafage, MSc ; Justin S. Smith, MD, PhD ; Muhammad B. Janjua, MD7; Christopher P. Ames, MD8 FDA Device/Drug Status: This abstract does not discuss or 1 include any applicable devices or drugs. NY Spine Institute, NYU Langone Health, New York, NY, US; 2NYU Langone Hospital, New York NY, US; 3New York, NY, US; 4Department of Orthopaedic Surgery, SUNY Downstate Medical P87. Does short segment reduction and fusion (TLIF) Center, Brooklyn, NY, US; 5Hospital for Special Surgery, New of spondylolytic spondylolisthesis normalise lumbar York, NY, US; 6UVA Health System, Charlottesville, VA, US; 7Mercy lordosis and improve spino-pelvic alignment? Health, Rockford, IL, US; 8University of California, San Francisco, Tom Robinson, FRCS (Tr & Orth), MBBS; Timothy Boddice, MBBS, San Francisco, CA, US MSc; Harry Fitzjohn, MBBS, BS; Rajesh R. Shah, FRCS FDA Device/Drug Status: This abstract does not discuss or Hull & East Yorkshire NHS Trust, Hull, Humberside, United include any applicable devices or drugs. Kingdom FDA Device/Drug Status: This abstract does not discuss or P91. Patient-reported outcomes and as treated analysis include any applicable devices or drugs. from the minimize implants maximize outcomes clinical trial P88. Extended length of stay after complex adult spinal Annalise N. Larson, MD1; David W. Polly Jr., MD2; Paul D. Sponseller, deformity surgery: predictors and impact on clinical and MD3; B. Stephens Richards, MD4; Sumeet Garg, MD5; Stefan Parent, patient-reported outcomes MD; Suken A. Shah, MD6; Stuart L. Weinstein, MD6; Charles H. 7 8 6 1 2 3 Crawford III, MD ; James Sanders, MD ; Michael P. Kelly, MD ; Jun S. Kim, MD ; Nathan J. Lee, MD ; Joseph M. Lombardi, MD ; 9 10 1 7 Laurel Blakemore, MD ; Matthew Oetgen, MD ; Nicholas D. Andrew C. Vivas, MD ; Scott L. Zuckerman, MD ; Jay S. Reidler, 11 12 13 4 5 6 Fletcher, MD ; Ann M. Brearley, PhD ; Carl-Eric Aubin, PhD ; MD, MPH ; Meghan Cerpa, MPH ; Eric Leung, BA ; Ronald A. Daniel J. Sucato, MD4; Hubert Labelle, MD14; Mark A. Erickson, MD15 Lehman Jr., MD7; Lawrence G. Lenke, MD8 1 2 1 2 Mayo Clinic, Rochester, MN, US; University of Minnesota, New York, NY, US; Columbia University, New York, NY, US; 3 4 3 Minneapolis, MN, US; Baltimore, MD, US; Texas Scottish Rite Columbia University Department of Orthopaedic Surgery, New 5 4 Hospital for Children, Dallas, TX, US; Children’s Hospital Colorado, York, NY, US; Johns Hopkins Hospital, Baltimore, MD, US; 6 5 6 Aurora, CO, US; DuPont Hospital for Children, Wilmington, DE, US; Columbia University Medical Center, New York, NY, US; The 7 8 7 Norton Leatherman Spine Center, Louisville, KY, US; University of Spine Hospital, New York, NY, US; The Spine Hospital -Columbia 9 8 North Carolina at Chapel Hill, Chapel Hill, NC, US; UF Orthopaedics University/New York Presbyterian, New York, NY, US; Columbia & Sports Medicine Institute, Gainesville, FL, US; 10Children’s University Department of Orthopedic Surgery, New York, NY, US National Hospital, Washington, DC, US; 11Children’s Healthcare of FDA Device/Drug Status: This abstract does not discuss or Atlanta, Atlanta, GA, US; 12Biostatistical Design and Analysis Center, include any applicable devices or drugs. University of Minnesota, Minneapolis, MN, US; 13Polytechnique Montréal, Montréal, QC, Canada; 14Département d’orthopédie, Montreal, QC, Canada; 15Aurora, CO, US FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. Abstracts 103

P92. Does BMI over 40 have a significant risk in spine P97. Correlation of UIV and cervical spine surgery to deformity patients? functional outcomes in AIS: a minimum 40-years Yaroslav J. Gelfand, MD1; Rafael De la Garza Ramos, MD2; Joshua follow-up Benton, BA3; Murray Echt, MD4; Vijay Yanamadala, MD5; Reza Aron Sulovari, BA1; Adan Omar, MD2; Emmanuel N. Menga, MD1; Yassari, MD, MSc1 Paul T. Rubery Jr., MD3; James Sanders, MD4; Addisu Mesfin, MD5 1Montefiore Medical Center, Bronx, NY, US;2 Montefiore Medical 1University of Rochester School of Medicine and Dentistry, Center, Department of Neurosurgery, Spine Research Group, Rochester, NY, US; 2URMC Orthopaedics and Rehabilitation, Bronx, NY, US; 3Albert Einstein College of Medicine, Bronx, NY, US; Rochester, US; 3Rochester, NY, US; 4University of North Carolina 4Bronx, NY, US; 5Stamford, CT, US at Chapel Hill, Chapel Hill, NC, US; 5University of Rochester, FDA Device/Drug Status: This abstract does not discuss or Rochester, NY, US include any applicable devices or drugs. FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. P93. The global alignment and proportion (GAP) score needs a modified LDI parameter: creating the GAP-D score P98. Radiographic sagittal alignment in the asymptomatic Jeffrey Kim, MD; Woojin Cho, MD, PhD; Ariella Applebaum, BA; elderly: what is normal for age? Adam D. Nessim, BS David McConda, MD1; Susan Odum, PhD2; Matt Chapman, MD3; P. 3 Bronx, NY, US Bradley Segebarth, MD 1 2 FDA Device/Drug Status: This abstract does not discuss or Bluegrass Spine Care, Shelbyville, KY, US; Atrium Health include any applicable devices or drugs. Musculoskeletal Institute, OrthoCarolina Research Institute, Charlotte, NC, US; 3OrthoCarolina Spine Center, Charlotte, NC, US FDA Device/Drug Status: This abstract does not discuss or P94. Global alignment and proportion (GAP) score with include any applicable devices or drugs. modified RLL parameter: GAP-L score Adam D. Nessim, BS; Woojin Cho, MD, PhD; Jeffrey Kim, MD; Ariella Applebaum, BA P99. The utility of computer-assisted navigation and intraoperative neuromonitoring for adult spinal deformity Bronx, NY, US surgery: a national claims database study FDA Device/Drug Status: This abstract does not discuss or Tanmaya Sambare, BA; Jayme C.B. Koltsov, PhD; Sariah include any applicable devices or drugs. Khormaee, MD, PhD; Ivan Cheng, MD Department of Orthopaedic Surgery, Stanford University School P95. Lower Hounsfield units (HU) of the upper of Medicine, Redwood City, CA, US instrumented vertebrae (UIV) may contribute to proximal FDA Device/Drug Status: This abstract does not discuss or junctional kyphosis (PJK) in adult spinal deformity (ASD) include any applicable devices or drugs. surgery Ping G. Duan, PhD, MD1; Sigurd H. Berven, MD2; Joshua Rivera3; Zhuo Xi, MD, PhD4; Shane Burch, MD5; Dean Chou, MD5 P100. Upper instrumented vertebral pelvic angle and risk of proximal junctional kyphosis at two year follow-up 1UCSF Spine Center, University of California San Francisco, 1 2 1 San Francisco, CA, US; 2UCSF, Dept of Orthopaedic Surgery, Hao-Hua Wu, MD ; Dean Chou, MD ; Joshua Rivera ; Ping G. 3 2 4 San Francisco, CA, US; 3San Francisco, CA, US; 4Neurosurgery Duan, PhD, MD ; Shane Burch, MD ; Sigurd H. Berven, MD Department Shengjing Hospital of China Medical University, 1San Francisco, CA, US; 2University of California San Francisco, Liaoning, Shenyang, China; 5University of California San San Francisco, CA, US; 3UCSF Spine Center, University of Francisco, San Francisco, CA, US California San Francisco, San Francisco, CA, US; 4UCSF, Dept of FDA Device/Drug Status: This abstract does not discuss or Orthopaedic Surgery, San Francisco, CA, US include any applicable devices or drugs. FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. P96. Moderate scoliosis continues to progress at 30 year follow up. A call for concern? P101. Distal junctional failure: a feared complication of Christopher Alcala, MD; Amir A. Mehbod, MD; Timothy A. Garvey, adult spinal deformity surgery MD; Joseph H. Perra, MD; Ensor E. Transfeldt, MD Houssam Bouloussa, MD, MS1; Soufiane Ghailane, MD2 Twin Cities Spine Center Piper Building, Minneapolis, MN, US 1UPMC Medical Education, Pittsburgh, PA, US; 2CHU Bordeaux FDA Device/Drug Status: This abstract does not discuss or Spine Unit 1 - Service Pr VITAL, Bordeaux, France include any applicable devices or drugs. FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. Abstracts 104

Surgery Cervical ePosters P105. The influence of standalone cage versus plate- augmented single-level ACDF on global and local cervical P102. The relative impact of myelopathic degree on sagittal alignment postoperative outcomes in operative cervical deformity Daniel Kiridly, MD, MBA1; Cesar Iturriaga, DO2; Ashna Joseph, BS3; patients based on deformity severity Jesse M. Galina, BS4; Peter Olivares, BS5; Alexander M. Satin, MD6; 7 8 1 2 3 Jeffrey A. Goldstein, MD ; Dean C. Perfetti, MD, MPH ; Austen Peter G. Passias, MD ; Katherine E. Pierce, BS ; Waleed Ahmad ; 9 10 11 Sara Naessig, BS4 Katz, MD ; Rohit B. Verma, MD ; Jeff S. Silber, MD, DC ; David A. Essig, MD12 1 2 NY Spine Institute, NYU Langone Health, New York, NY, US; NYU 1 3 4 Northwell Health Orthopaedic Surgery, New Hyde Park, NY, US; Spine Research Lab, New York, NY, US; New York, NY, US; NYU 2 3 4 Langone Hospital, New York NY, US New Hyde Park, NY, US; Hempstead, NY, US; New Hyde Path, NY, US; 5Northwell Health, New Hyde Park, NY, US; 6American FDA Device/Drug Status: This abstract does not discuss or Pain & Wellness, Plano, TX, US; 7Queens, NY, US; 8Department include any applicable devices or drugs. of Orthopedic Surgery, Long Island Jewish Medical Center, New Hyde Park, NY, US; 9Long Island Jewish Hospital, Queens, NY, US; P103. The modification of appropriateness criteria for a 10University Orthopaedic Associates, Great Neck, NY, US; 11Great cervical deformity corrective surgery Neck, NY, US; 12Northwell Health, Great Neck, NY, US Katherine E. Pierce, BS1; Waleed Ahmad2; Sara Naessig, BS3; FDA Device/Drug Status: This abstract does not discuss or Shaleen N. Vira, MD4; Renaud Lafage, MSc5; Virginie Lafage, PhD5; include any applicable devices or drugs. Aaron J. Buckland, MBBS, FRACS6; Themistocles S. Protopsaltis, MD6; Bassel G. Diebo, MD7; Peter G. Passias, MD8 P106. Impact of predominant preoperative symptoms on 1NYU Spine Research Lab, New York, NY, US; 2New York, NY, outcomes of CDR 3 4 US; NYU Langone Hospital, New York NY, US; Department Ryan Lee, MBA1; Avani S. Vaishnav, MBBS; Michael H. McCarthy, of Orthopaedic Surgery, UT Southwestern Medical Center, MD, MPH; Philip Louie, MD2; Sheeraz A. Qureshi, MD, MBA1 5 Dallas, TX, US; Hospital for Special Surgery, New York, NY, US; 1 2 6Department of Orthopedic Surgery, NYU Langone Orthopedic Hospital for Special Surgery, New York, NY, US; New York, NY, Hospital, NYU Langone Health , New York, NY, US; 7Department US of Orthopaedic Surgery, SUNY Downstate Medical Center, FDA Device/Drug Status: This abstract does not discuss or Brooklyn, NY, US; 8NY Spine Institute, NYU Langone Health, New include any applicable devices or drugs. York, NY, US FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. Surgery Thoracolumbar ePosters

P107. Are modic changes associated with health-related P104. A review of time demand, radiation exposure quality of life after discectomy? and outcomes of skin-anchored intraoperative 3D navigation in minimally invasive posterior cervical Peter Udby, MD1; Leah Y. Carreon, MD, MSc2; Mikkel Andersen, laminoforaminotomy MD3; Søren Ohrt-Nissen, MD, PhD4; Stig Brorson, MD, PhD5 Avani S. Vaishnav, MBBS; Philip Louie, MD1; Steven J. McAnany, 1Zealand University Hospital, Department of Orthopedic Surgery, MD2; Sravisht Iyer, MD3; Todd J. Albert, MD3; Catherine Himo Køge, Zealand, Denmark; 2Sygehus Lillebælt - Rygkirurgi Gang, MPH3; Sheeraz A. Qureshi, MD, MBA3 Middelfart, Middelfart, Middelfart, Denmark; 3Middelfart, Denmark; 4Copenhagen, Denmark; 5Zealand University Hospital, 1New York, NY, US; 2Hospital for Special Surgery, Stamford, CT, Dept. of Orthopaedic Surgery, Koege, Denmark US; 3Hospital for Special Surgery, New York, NY, US FDA Device/Drug Status: This abstract does not discuss or FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. include any applicable devices or drugs.

P108. Propensity-matched comparison of open, navigated and robotic-assisted TLIF Leah Y. Carreon, MD, MSc1; Morgan Brown, MS2; Christy L. Daniels, MS1 1Norton Leatherman Spine Center, Louisville, KY, US; 2Norton Healthcare, Louisville, KY, US FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. Abstracts 105

P109. Improvements in screw placement and accuracy P114. Intraoperative transverse process fractures and with newer generation robotic-assisted minimally posterolateral lumbar fusion rates invasive instrumented lumbar fusions David H. Kim, MD1; Raymond Hwang, MD, MS, MBA2; Gyu Ho Samuel R. Schroerlucke, MD1; Elizabeth N. Harris, PA-C2; Rita Roy, Lee, MA3; Samuel W. Golenbock, MSc4; Kevin Baker, PhD5; Paul MD3 M. Arnold, MD6; Rick C. Sasso, MD7; Daniel K. Park, MD8; Jeffrey 9 1Tabor Orthopedics, Memphis, TN, US; 2Memphis, TN, US; Fischgrund, MD 3National Spine Health Foundation, Reston, VA, US 1Tufts University Medical Group, NEBH, Boston, MA, US; 2New FDA Device/Drug Status: This abstract does not discuss or England Baptist Hospital, New England Orthopedic and Spine 3 include any applicable devices or drugs. Surgery, Chestnut Hill, MA, US; Icahn School of Medicine at Mount Sinai, New York, NY, US; 4New England Baptist Hospital, Boston, MA, US; 5Beaumont Health, Royal Oak, MI, US; 6Carle P110. Hospital network participation and outcomes Foundation Hospital , Urbana, IL, US; 7Indiana Spine Group, following elective posterior lumbar fusions: are mergers Carmel, IN, US; 8Southfield, MI, US;9 Franklin, MI, US warranted? FDA Device/Drug Status: This abstract does not discuss or Azeem T. Malik, MBBS1; Elizabeth Yu, MD2; Joseph Drain, MD2; include any applicable devices or drugs. Jeffery Kim, MD1; Safdar N. Khan, MD1

1 The Ohio State University Wexner Medical Center, Columbus, P115. Patients with degenerative spondylolisthesis 2 OH, US; Columbus, OH, US maintain clinically relevant improvement five years after FDA Device/Drug Status: This abstract does not discuss or surgery include any applicable devices or drugs. Andreas K. Andresen, MD1; Christian C. Stoettrup, MD2; Rune T. Paulsen, MD3; Peter Udby, MD4; Soren Fruensgaard, MD5; Leah Y. P111. Undergoing elective posterior lumbar fusions at “US Carreon, MD, MSc6 News & World Report” ranked hospitals versus non-ranked 1Spine Center of Southern Denmark, Middelfart, Denmark; hospitals: do rankings even matter? 2Lillebaelt Hospital, Middelfart, Denmark; 3Lillebaelt Hospital, 4 Azeem T. Malik, MBBS1; Frank M. Phillips, MD2; Jeffery Kim, MD1; Middelfart, Region Syddanmark, Denmark; Zealand University Elizabeth Yu, MD3; Safdar N. Khan, MD1 Hospital, Department of Orthopedic Surgery, Køge, Zealand, 5 1 Denmark; Silkeborg Central Hospital, Silkeborg, Denmark; The Ohio State University Wexner Medical Center, Columbus, 6Sygehus Lillebælt - Rygkirurgi Middelfart, Denmark OH, US; 2Midwest Orthopaedics At Rush, Chicago, IL, US; 3Columbus, OH, US FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. P116. Comparing short term complications of inpatient versus outpatient elective vertebral augmentation for P112. Role of metabolites in bio-fluids as a prognostic osteoporotic vertebral compression fractures indicator of neurological recovery in Acute Spinal Cord Injury (ASCI) John Shin, MD1; Colin B. Harris, MD2; Michael J. Vives, MD1 1 2 Rajeshwar N. Srivastava, MD1; Dr Alka Singh, PhD2; Saloni Raj, Rutgers New Jersey Medical School, Newark, NJ, US; Rutgers - MPH3 New Jersey Medical School, Essex Fells, NJ, US 1King George’s Medical University, Dept of Ortho Surgery, FDA Device/Drug Status: This abstract does not discuss or Lucknow, India; 2Dept. of Orthopaedic Surgery, Lucknow, India; include any applicable devices or drugs. 3Department of Orthopaedic Surgery King George’s Medical University, Lucknow, Uttar Pradesh, India P117. Navigated robotic assistance improves pedicle FDA Device/Drug Status: This abstract does not discuss or screw accuracy in minimally invasive surgery of the include any applicable devices or drugs. thoracolumbar spine: 341 patients in a single institution Arnold B. Vardiman, MD1; David J. Wallace, MD2; Neil Crawford, P113. Pedicle morphology of the lumbar spine in a diverse PhD3; Jessica Riggleman, BS4; Samantha Greeley, BA4; Charles population Gerald T. Ledonio, MD, CCRP5; Grant Jamgochian, BS4; Brandon Bucklen, PhD4 Brandon Petrone, DO1; Thomas J. Dowling III, MD2; Jordan 1 Fakhoury, DO3; Joseph Albano, DO4; Robert C. Stockton, DO; Neurosurgical Associates of San Antonio, San Antonio, TX, US; 2 3 Jonathon M. Lentz, DO2; Kanwarpaul S. Grewal, DO5 UT Health San Antonio, San Antonio, TX, US; Globus Medical, 4 5 1 2 Tempe, AZ, US; Globus Medical, Audubon, PA, US; Audubon, Plainview, NY, US; Northwell Health, Plainview Hospital, PA, US Plainview, NY, US; 3Northwell, Carle Place, NY, US; 4Long Island City, NY, US; 5Island Musculoskeletal Care, Hewlett, NY, US FDA Device/Drug Status: Excelsius GPS (Globus Medical) (Approved for this indication) FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. Abstracts 106

P118. Pelvic fixation improves coronal balance, decreases P122. Use of a novel allograft in single- and two-level pelvic obliquity, but is not essential in neuromuscular posterolateral lumbar spinal fusion: two year clinical and scoliosis (NMS) radiographic results from a prospective multicenter study Vishal Sarwahi, MD1; Jesse M. Galina, BS2; Beverly Thornhill, MD3; Scott D. Daffner, MD1; Joshua Bunch, MD2; Howard S. An, MD3; Kathleen Maguire, MD4; Sayyida S. Hasan, BS5; Jordan Fakhoury, Douglas C. Burton, MD2; Robert. Milam IV, MD4; Daniel K. Park, DO6; Thomas J. Dowling III, MD7; Terry D. Amaral, MD8 MD5; K. Brandon Strenge, MD6; Peter G. Whang, MD, FACS7 1North Shore LIJ Health System, New Hyde Park, NY, US; 2New 1West Virginia University School of Medicine, Morgantown, WV, Hyde Path, NY, US; 3Albert Einstein College of Medicine, Bronx, US; 2University of Kansas Medical Center, Kansas City, KS, US; NY, US; 4Montefiore Medical Center, Bronx, NY, US;5 Cohen 3Rush University Medical Center, Department of Orthopedic Children’s Medical Center, New Hyde Park, NY, US; 6Northwell, Surgery, Chicago, IL, US; 4OrthoCarolina Spine Center, Charlotte, Carle Place, NY, US; 7Northwell Health, Plainview Hospital, NC, US; 5Southfield, MI, US;6 The Orthopaedic Institute of Western Plainview, NY, US; 8Northwell Health, Lake Success, NY, US Kentucky, Paducah, KY, US; 7Yale University - School of Medicine, FDA Device/Drug Status: This abstract does not discuss or New Haven, CT, US include any applicable devices or drugs. FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. P119. Comparison of five-year outcomes between wide laminectomy, segmental bilateral laminotomies and P123. 24-month outcomes of a prospective investigation unilateral hemi-laminectomy for lumbar spinal stenosis of a novel mesh interbody spacer in single level fusions Jamal Bech Bouknaitir, MD1; Leah Y. Carreon, MD, MSc2; Stig Pierce D. Nunley, MD1; John H. Chi, MD; Martin H. Krag, MD2; Brorson, MD, PhD3; Casper Friis Pederson, Cand.Scient.4; Mikkel Mohamad Bydon, MD3; Stephane Lavoie, MD4; Yi Lu, MD, PhD5; Andersen, MD5 Marcus Stone, PhD6 1Zealand University Hospital, Koege, Denmark; 2Sygehus Lillebælt 1Spine Institute of Louisiana, Shreveport, LA, US; 2Dept of - Rygkirurgi Middelfart, Denmark; 3Zealand University Hospital, Orthopaedics & Rehab Univ. of Vermont, Burlington, VT, US; Dept. of Orthopaedic Surgery, Koege, Denmark; 4Centre for 3Mayo Clinic, Rochester, MN, US; 4Florida Orthopedic Associates, Spine Surgery and Research, Spine Centre of Southern Denmark, Deland, FL, US; 5Brigham & Women’s Hospital, Boston, MA, US; Hospital Lillebaelt, Middelfart, Denmark; 5Middelfart, Denmark 6Spine Institute of Louisiana Foundation, Shreveport, LA, US FDA Device/Drug Status: This abstract does not discuss or FDA Device/Drug Status: OptiMesh (Not approved for this include any applicable devices or drugs. indication)

P120. Five-year patient reported outcomes ABM/P-15 P124. The Lordosing Effect of the prone transpsoas versus allograft in non-instrumented posterolateral Technique: preliminary results of a multicenter fusion experience Mikkel Andersen, MD1; Michael K. Jacobsen, MD2; Soren Antoine Tohmeh, MD1; Luiz Pimenta, MD, PhD2; Gabriel Pokorny, Overgaard, MD, PhD3; Leah Y. Carreon, MD, MSc4 BS3; Ashish Patel, MD4; Rodrigo A. Amaral, MD5; William R. Taylor, 6 1Middelfart, Denmark; 2Spine Surgery and Research, Spine Center MD of Southern Denmark- part of Lillebaelt Hospital, Middelfart, 1MultiCare Neuroscience Institute, Spokane Valley, WA, US; 2IPC, Southern Denmark, Denmark; 3Odense University Hospital, Sao Paulo, Brazil; 3Guaratuba, 280, São Paulo, Brazil; 4Dupage Odense, Denmark; 4Sygehus Lillebælt - Rygkirurgi Middelfart, Medical Group, Naperville, IL, US; 5IPC - Instituto de Patologia da Denmark Coluna, Sao Paulo, Brazil; 6University of California San Diego - FDA Device/Drug Status: ABM/P-15 (Investigational/Not Dept of Neurosurgery, La Jolla, CA, US approved) FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. P121. Fusion rate for stand-alone lateral lumbar interbody fusion: a systematic review P125. Concurrence presence of thoracolumbar scoliosis Mustfa K. Manzur, MPH, MS, BS1; Michael E. Steinhaus, MD2; and Arnold Chiari Malformation: is operative risk Sohrab Virk, MD2; Bridget Jivanelli, MS, BA3; Avani S. Vaishnav, magnified MBBS; Steven J. McAnany, MD4; Sravisht Iyer, MD2; Todd J. Albert, Peter G. Passias, MD1; Sara Naessig, BS2; Waleed Ahmad3; MD2; Catherine Himo Gang, MPH2; Sheeraz A. Qureshi, MD, MBA2 Katherine E. Pierce, BS4; Muhammad B. Janjua, MD5; Bassel G. 1Thomas Jefferson University, Philadelphia, PA, US; 2Hospital for Diebo, MD6 Special Surgery, New York, NY, US; 3New York, NY, US; 4Hospital 1NY Spine Institute, NYU Langone Health, New York, NY, US; 2NYU for Special Surgery, Stamford, CT, US Langone Hospital, New York NY, US; 3New York, NY, US; 4NYU FDA Device/Drug Status: This abstract does not discuss or Spine Research Lab, New York, NY, US; 5Mercy Health, Rockford, include any applicable devices or drugs. IL, US; 6Department of Orthopaedic Surgery, SUNY Downstate Medical Center, Brooklyn, NY, US FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. Abstracts 107

P126. Psychometric evaluation of PROMIS physical P130. Does the utilization of comprehensive surgical function computer adaptive testing in minimally invasive planning software improve postoperative sagittal lumbar spine surgery: an analysis of responsiveness, alignment: an interim multicenter analysis coverage, discriminant validity and concurrent validity Isaac O. Karikari, MD1; Robert K. Eastlack, MD2; Adam S. Kanter, Avani S. Vaishnav, MBBS; Steven J. McAnany, MD1; Sravisht Iyer, MD3; Jonathan N. Sembrano, MD4; Donald J. Blaskiewicz, MD5; MD2; Todd J. Albert, MD2; Catherine Himo Gang, MPH2; Sheeraz A. Antoine Tohmeh, MD6; Oren N. Gottfried, MD7; Arash Emami, MD8; Qureshi, MD, MBA2 Jim A. Youssef, MD9; Sahir Jabbouri, BS10; David O. Okonkwo, 11 1Hospital for Special Surgery, Stamford, CT, US; 2Hospital for MD Special Surgery, New York, NY, US 1Duke University Medical Center, Durham, NC, US; 2Scripps Clinic, 3 FDA Device/Drug Status: This abstract does not discuss or San Diego, CA, US; UPMC-Presbyterian/Dept of Neurological 4 include any applicable devices or drugs. Surgery, Pittsburgh, PA, US; University of Minnesota, Minneapolis, MN, US; 5Spine Institute of Idaho, Meridian, ID, US; 6MultiCare Neuroscience Institute, Spokane Valley, WA, US; 7Duke P127. PROMIS better reflects the impact of length of University, Durham, NC, US; 8University Spine Center, Wayne, NJ, stay and the occurrence of complications within 90 days US; 9Spine Colorado, Durango, CO, US; 10Multicare Neuroscience than legacy outcome measures for lumbar degenerative Institute , Spokane, WA, US; 11Pittsburgh, PA, US surgery FDA Device/Drug Status: This abstract does not discuss or Sara Naessig, BS1; Cole Bortz, BA2; Katherine E. Pierce, BS3; include any applicable devices or drugs. Waleed Ahmad2; Shaleen N. Vira, MD4; Bassel G. Diebo, MD5; 6 7 Aaron J. Buckland, MBBS, FRACS ; Peter G. Passias, MD P131. The association of comorbidity burden on lumbar 1NYU Langone Hospital, New York NY, US; 2New York, NY, US; decompression postoperative outcomes 3 4 NYU Spine Research Lab, New York, NY, US; Department of James Parrish, MPH1; Nathaniel Jenkins, BS, MS1; Evan Sheha, Orthopaedic Surgery, UT Southwestern Medical Center, Dallas, MD2; Nadia Hrynewycz, BS3; Thomas Brundage, BS4; Kern Singh, 5 TX, US; Department of Orthopaedic Surgery, SUNY Downstate MD1 Medical Center, Brooklyn, NY, US; 6Department of Orthopedic 1 2 Surgery, NYU Langone Orthopedic Hospital, NYU Langone Health, Rush University Medical Center, Chicago, IL, US; Rush 3 4 New York, NY, US; 7NY Spine Institute, NYU Langone Health, New University, Chicago, IL, US; Chicago, IL, US; Midwest York, NY, US Orthopedics at Rush, Chicago, IL, US FDA Device/Drug Status: This abstract does not discuss or FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. include any applicable devices or drugs.

P132. Is there a difference in clinical outcomes between P128. Spinal cord stimulation decreases pain and single level and two level anterior lumbar interbody fusion disability in patients with non-radicular, nonoperative for degenerative disc disease? chronic axial low back pain Bryce Basques, MD, MHS1; Garrett Harada, MD2; Krishn Khanna, Benjamin C. Dorenkamp, DO1; John M. Popovich Jr., PhD, DPT, MD; Samuel Rudisill, BS4; Zakariah Siyaji, BS3; Omar Alam, MD4; ATC2; Kaitlin O’Hagan, DO3; John N. Flood, DO4 Frank M. Phillips, MD3 1Mclaren Greater Lansing, Lansing, MI, US; 2MSU Center for 1Thomas Jefferson University, Philadelphia, PA, US; 2Los Angeles, Orthopedic Research, Lansing, MI, US; 3Michigan State University, CA, US; 3Midwest Orthopedics at Rush, Chicago, IL, US; 4Rush Lansing, MI, US; 4Michigan Orthopedic Center, Lansing, MI, US University Medical Center, Chicago, IL, US FDA Device/Drug Status: Boston Scientific Coverage Lead with FDA Device/Drug Status: This abstract does not discuss or Precision Spectra Spinal Cord Stimulator System (Approved for include any applicable devices or drugs. this indication) P133. Does bone morphogenic protein (BMP) use reduce P129. Outcome analysis of expandable cage use in pseudoarthrosis rates in singlelevel TLIF surgeries? transforaminal lumbar interbody fusions Jack Zhong, BA1; Jarid Tareen, MD; Kimberly Ashayeri, MD2; Carolyn Stickley, BS1; Travis C. Philipp, MD2; Erik Wang, BA3; Jack Carlos Leon, BS3; Eaman Balouch, MD, PhD2; Carolyn Stickley, Zhong, BA4; Ethan W. Ayres, MPH3; Eaman Balouch, MD, PhD5; BS4; Nicholas O’Malley, BS5; Constance Maglaras, PhD6; Brooke K. Nicholas O’Malley, BS6; Carlos Leon, BS7; Constance Maglaras, O’Connell, MS2; Ethan W. Ayres, MPH6; Aaron J. Buckland, MBBS, PhD5; Jordan H. Manning, BA3; Christopher Varlotta, BS3; Aaron J. FRACS7 Buckland, MBBS, FRACS8 1NYU Langone Spine Research Center, New York, NY, US; 2New 1Department of Orthopedic Surgery, NYU Langone Health, York, NY, US; 3NYU Langone Medical Center, New York City, NY, New York, NY, US; 2NYU Langone Health, New York, NY, US; US; 4Department of Orthopedic Surgery, NYU Langone Health, 3Department of Orthopedic Surgery, NYU Langone Orthopedic New York, NY, US; 5NYU Langone Dept. of Orthopedic Surgery, Hospital, NYU Langone Health, New York, NY, US; 4NYU Langone Division of Spine, New York, NY, US; 6Department of Orthopedic Spine Research Center, New York , NY, US; 5New York, NY, US; Surgery, NYU Langone Orthopedic Hospital, NYU Langone Health, 6NYU Langone Dept. of Orthopedic Surgery, Division of Spine, New York, NY, US; 7Department of Orthopedic Surgery, NYU New York, NY, US; 7NYU Langone Medical Center, New York Langone Orthopedic Hospital, NYU Langone Health , New York, City, NY, US; 8Department of Orthopedic Surgery, NYU Langone NY, US Orthopedic Hospital, NYU Langone Health, New York, NY, US FDA Device/Drug Status: This abstract does not discuss or FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. include any applicable devices or drugs. Abstracts 108

P134. Higher rates of medical complications and costs of P138. Crossing the junction: effect of fusion length on care following delayed surgical intervention for Cauda reoperations for revision thoracolumbar fusion to sacrum Equina Syndrome: a matched-control analysis Jack Zhong, BA1; Eaman Balouch, MD, PhD2; Nicholas O’Malley, Ajit Vakharia, MD1; Walter B. Klyce, MD2; Yazdan Raji, MD3; Jerry Y. BS3; Carlos Leon, BS4; Carolyn Stickley, BS5; Constance Maglaras, Du, MD4; Nicholas U. Ahn, MD5 PhD2; Ethan W. Ayres, MPH5; Karan S. Patel, MD7; Yong H. Kim, 6 5 1University Hospitals Cleveland Medical Center, Case Western MD ; Themistocles S. Protopsaltis, MD ; Aaron J. Buckland, 5 Reserve University, Dept of Orthopaedic Surgery, Cleveland, OH, MBBS, FRACS US; 2University Hospitals, Cleveland, OH, US; 3University Hospitals 1NYU Langone Spine Research Center, New York , NY, US; 2New Cleveland Medical Center, Cleveland, OH, US; 4University York, NY, US; 3NYU Langone Dept. of Orthopedic Surgery, Division Hospitals Cleveland Medical Center/ Case Western Reserve of Spine, New York, NY, US; 4NYU Langone Medical Center, New University, Cleveland, OH, US; 5University Hospital of Cleveland, York City, NY, US; 5Department of Orthopedic Surgery, NYU Department of Orthopedic Surgery, Cleveland, OH, US Langone Health, New York, NY, US 6NYU Langone Orthopedic FDA Device/Drug Status: This abstract does not discuss or Hospital, New York, NY, US include any applicable devices or drugs. Orthopaedic Hospital, NYU Langone Health, New York, NY, US; 9Department of Orthopedic Surgery, NYU Langone Orthopedic Hospital, NYU Langone Health, New York, NY, US P135. Sagittal balance and outcomes after MIS TLIF for short-segment degenerative spondylolisthesis FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. Andre Samuel, MD1; Yahya A. Othman2; Avani S. Vaishnav, MBBS; Steven J. McAnany, MD3; Sravisht Iyer, MD1; Todd J. Albert, MD1; Catherine Himo Gang, MPH1; Sheeraz A. Qureshi, MD, MBA1 1Hospital for Special Surgery, New York, NY, US; 2Weill Cornell Trauma ePosters Medicine, Qatar Foundation, Rayyan, Qatar; 3Hospital for Special P139. High rate of mortality after spinal trauma in patients Surgery, Stamford, CT, US with ankylosing spondylitis

FDA Device/Drug Status: This abstract does not discuss or 1 2 include any applicable devices or drugs. Mitchel Harris, MD, FACS ; Abhishek Keraliya, MD ; Bharti Khurana, MD2; David Sing, MD3 1Massachusetts General Hospital, Boston, MA, US; 2Brigham and P136. Clinical and radiographic outcomes after lumber Women’s Hospital, Department of Radiology, Boston, MA, US; decompression with placement of interlaminar spacers 3Boston Medical Center, Boston, MA, US versus decompression alone FDA Device/Drug Status: This abstract does not discuss or Eren O. Kuris, MD1; Bradley Reeves, BS2; Nolan M. Wessell, MD3; include any applicable devices or drugs. Christopher Kleck, MD3; Vikas V. Patel, MD2; Evalina L. Burger, MD4 1Brown University Department of Orthopaedics, Providence, RI, P140. Delayed diagnosis impacted on delayed paralysis US; 2University of Colorado School of Medicine, Aurora, CO, US; in spinal fractures with diffuse idiopathic skeletal 3University of Colorado, Aurora, CO, US; 4Dept of Orthopaedics - hyperostosis: prospective nationwide study UCDenver, Aurora, CO, US Ejiiro Okada, MD1; Kanichiro Wada, MD, PhD2; Tatsuya Yasuda, FDA Device/Drug Status: This abstract does not discuss or 3 4 5 include any applicable devices or drugs. MD ; Kanji Mori, MD, PhD ; Shunji Matsunaga, MD ; Hiroyuki Katoh, MD, PhD6; Toshitaka Yoshii, MD7; Atsushi Okawa, MD, PhD8; Morio Matsumoto, MD9; Kota Watanabe, MD10 P137. Osteoporosis is a predictor of two-year adverse 1Saiseikai Central Hospital, Tokyo, Japan; 2Department of outcomes following short fusion for degenerative lumbar Orthopaedic Surgery, Hirosaki University Graduate of Medicine, disease Hirosaki, Aomori, Japan; 3Hamamatsu Medical Center, Salem Najjar, BA1; Adam J. Wolfert, BA2; Alexander Rompala, BA2; Hamamatsu, Japan; 4Shiga University of Medical Science/ Dept George A. Beyer, MS2; Harleen Kaur, BA2; Dillon Sedaghatpour, of Orthop Surgery, Otsu, Japan; 5Kagoshima, Japan; 6Tokai MD2; Neil V. Shah, MD, MS3; Peter G. Passias, MD4; Virginie University School of Medicine, Kanagawa, Japan; 7Tokyo Medical Lafage, PhD5; Frank J. Schwab, MD5; Bassel G. Diebo, MD3; Carl B. & Dental University, Tokyo, Japan; 8Bunkyo-Ku, Japan; 9Keio Paulino, MD2 University School of Medicine, Tokyo, Japan; 10Keio University, 1Zucker School of Medicine at Hofstra/Northwell, Hempstead, Keio, Japan NY, US; 2SUNY Downstate Medical Center, Brooklyn, NY, US; FDA Device/Drug Status: This abstract does not discuss or 3Department of Orthopaedic Surgery, SUNY Downstate Medical include any applicable devices or drugs. Center, Brooklyn, NY, US; 4NY Spine Institute, NYU Langone Health, New York, NY, US; 5Hospital for Special Surgery, New York, NY, US FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. Abstracts 109

Innovative Technology Presentations 5. Nano-scale surface features of a novel PEEK Titanium Composite (PTC) interbody cage: a morphological and (Non-CME) cellular evaluation 1; Jiechao Jiang, PhD2; Nora Bloise, PhD3; 1. Comparison between patient-specific interbody Erik I. Waldorff, PhD Giulia Montagna3; Livia Visai, PhD3; Sam Fang4; Nianli Zhang, devices vs stock devices in achieving the planned PhD4; James T. Ryaby, PhD1 correction in the treatment of adult spinal deformity 1Orthofix, Lewisville, TX, US;2 Materials Science and Engineering Justin L. Esterberg, MD1; Niall Casey2 Department, Arlington, TX, US; 3University of Pavia, Pavia, Italy; 1Mercer Island, WA, US; 2Carlsmed, La Jolla, CA 4Lewisville, TX, US FDA Device/Drug Status: The Carlsmed personalized interbody FDA Device/Drug Status: FORZA PTC (Approved for this devices presented in this study are not cleared by the US FDA. indication), Pillar SA PTC (Approved for this indication), (Not approved for this indication) CONSTRUX Mini PTC (Approved for this indication)

2. Does implant profile matter for SI construct stability? 6. Viable cellular bone allografts can support Sam Fang angiogenesis in vitro 2 Lewisville, TX, US Anouska Dasgupta, PhD1; Adiba Chowdhury, MS 1 FDA Device/Drug Status: This abstract does not discuss or Musculoskeletal Transplant Foundation (MTF), Edison, NJ, US; 2 include any applicable devices or drugs. MTF Biologics, Edison, NJ, US FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs. 3. Preliminary clinical and radiographic results from a multicenter, prospective lumbar spinal fusion study of the Trinity ELITE Allograft 7. Brushite coating on 3D printed Ti-porous structures for optimal osteointegration Anthony J. Russo, MD1; Daniel K. Park, MD2; J. Rafe Sales, MD3; Timothy Peppers, MD4; Joshua Wind, MD5; Hamid Hassanzadeh, Mukesh Kumar, PhD MD6 Bartlett, TN, US 1Montana Orthopedics, Butte, MT, US; 2Southfield, MI, US; FDA Device/Drug Status: This abstract does not discuss or 3Summit Spine Institute, Portland, OR, US; 4Scripps Clinic Medical include any applicable devices or drugs. Group, Encinitas, CA, US; 5Washington Neurosurgical Associates, Washington, DC, US; 6University of Virginia, Department of Orthopedic Surgery, Charlottesville, VA, US 8. Can artificial intelligence support or even replace physicians in measuring the sagittal balance? A validation FDA Device/Drug Status: Trinity ELITE (Approved for this study on preoperative and postoperative images of 170 indication) patients Priyanka Grover, MSc1; Jakob Siebenwirth2; Christina Caspari2; 4. Improvements of quality of motion and associated Marcel Dreischarf, PhD1; Michael Putzier, MD3; Jörg Franke, PhD, patient outcomes: an analysis of two-year clinical results MD2 for a novel compressible core artificial cervical disc as 1Raylytic GmbH, Leipzig, Germany; 2Klinikum Magdeburg, compared to anterior cervical discectomy and fusion Magdeburg, Germany; 3Charité – University Berlin, Berlin, Frank M. Phillips, MD1; Rick C. Sasso, MD2; Todd H. Lanman, Germany MD3; William F. Lavelle, MD4; Scott L. Blumenthal, MD5; Carl FDA Device/Drug Status: This abstract does not discuss or Lauryssen, MD6; Richard D. Guyer, MD5; Todd J. Albert, MD7; Jack include any applicable devices or drugs. E. Zigler, MD8; Frank P. Cammisa, MD7; Robert Milam IV, MD9 1Midwest Orthopaedics at Rush, Chicago, IL, US; 2Indiana Spine Group, Carmel, IN, US; 3Beverly Hills, CA, US; 4Upstate 9. Comparative study on biomechanical and water Orthopedics, East Syracuse, NY, US; 5Center for Disc absorption properties of disc tissue particulate Replacement at Texas Back Institute, Plano, TX, US; 6Central Shabnam M. Namin, PhD1; Renaud Sicard, PhD2; Timothy Ganey, Texas Brain and Spine, Austin, TX, US; 7Hospital for Special PhD3 8 Surgery, New York, NY, US; Texas Back Institute, Plano, TX, US; 1 2 9 Vivex Biologics, Inc., Miami, FL, US; Vivex Biomedicals, Miami, OrthoCarolina Spine Center, Charlotte, NC, US FL, US; 3Vivex Biomedical, Atlanta, GA, US FDA Device/Drug Status: M6-C artificial cervical disc (Approved FDA Device/Drug Status: This abstract does not discuss or for this indication) include any applicable devices or drugs. Abstracts 110

10. Characterization of amniotic fluid for anti- inflammatory and immunomodulatory properties Shabnam M. Namin, PhD1; Renaud Sicard, PhD2; Timothy Ganey, PhD3; Tania del Rivero, PhD1 1Vivex Biologics, Inc., Miami, FL, US; 2Vivex Biomedicals, Miami, FL, US; 3Vivex Biomedical, Atlanta, GA, US FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs.

11. Co-culture with cryopreserved spine-derived cells attenuates TNF-induced inflammation in nucleus pulposus cells Shabnam M. Namin, PhD1; Renaud Sicard, PhD2; Timothy Ganey, PhD3; Jonathan Messer, PhD1 1Vivex Biologics, Inc., Miami, FL, US; 2Vivex Biomedicals, Miami, FL, US; 3Vivex Biomedical, Atlanta, GA, US FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs.

12. Understanding the relationship between osteoimmunology and bone response of PEEK, titanium and a novel PEEK-zeolite composite Sriram Sankar, MSc1; Joseph J. Crudden, MD2; Joseph Bartolacci3 1DiFusion Technologies, Inc., Austin, TX, US; 2Austin, TX, US; 3McGowan Institute for Regenerative Medicine, Pittsburgh, PA, US FDA Device/Drug Status: PEEK-ZEOLITE COMPOSITE (ZFUZE) (Approved for this indication), NANOLOCK TITANIUM (ENDOSKELETON) (Approved for this indication), PEEK (XIPHOS) (Approved for this indication)

13. 3DRTM printed lumbar interbody fusion system provides an advanced option for circumferential fusion of the lumbar spine James M. Mok, MD1; Faiz U. Ahmad, MD, M.Ch2; David B. Cain3; Wayne Gray3; Pam Cowart, APRN, MSN4 1DuPage Medical Group, Elmhurst, IL, US; 2Emory University, Emory Faculty Office Building, Atlanta, GA, US;3 Marietta, GA, US; 4MiRus, Marietta, GA, US FDA Device/Drug Status: MiRus 3DR Lumbar Interbody Fusion Device (Approved for this indication)

14. Comparison of a 3D printed truss-based lateral interbody device to an annular lateral interbody device for resistance to subsidence: a cadaveric study Ali Kiapour, PhD1; Puya Alikhani, MD2 1Boston, MA, US; 2Tampa, FL, US FDA Device/Drug Status: LSTS Truss Lateral Interbody System (Approved for this indication) Leadership Recognition 111

2019-2020 Board of Directors NASS thanks the following Board members for their leadership and guidance throughout the year:

William J. Sullivan, MD Patrick C. Hsieh, MD, MS President International Council Director

Eeric Truumees, MD Mitchell F. Reiter, MD, PC First Vice President Administration & Development Council Director

Edward J. Dohring, MD Paul M. Arnold, MD Second Vice President Ethics and Professionalism Committee Chair

John G. Finkenberg, MD Karin Swartz, MD Secretary Section Development Chair

David R. O’Brien, Jr., MD Richard L. Skolasky, ScD Treasurer Governance Committee Chair

Jeffrey C. Wang, MD Zoher Ghogawala, MD, FACS Past President Health Policy Council Director

Charles A. Reitman, MD Christopher Kauffman, MD Education Council Director Payer Policy Review Committee Chair

Thomas E. Mroz, MD William Mitchell, MD Continuing Medical Education Chair Coding Committee Chair

Jonathan N. Grauer, MD Philip L. Schneider, MD Education Publishing Chair Advocacy Council Director

Scott Kreiner, MD Michael G. Fehlings, MD, PhD, FRCSC Research Council Director At-Large Member

Charles H. Cho, MD, MBA Donna M. Lahey, RNFA, CNOR Evidence Compilation & Analysis Chair At-Large Member

Donna D. Ohnmeiss, PhD Eric J. Muehlbauer, MJ, CAE Clinical Research Development Chair Executive Director Leadership Recognition 112

2020 Scientific Program Committee NASS thanks the following members for their valued time, effort and dedication in planning the educational content for this year’s Annual Meeting:

William J. Sullivan, MD Thomas E. Mroz, MD President Patrick C. Hsieh, MD, MS David E. Fish, MD, MPH Donna M. Lahey, RNFA, CNOR Allen S. Chen, MD, MPH Michael G. Fehlings, MD, PhD, FRCSC Sanjog Pangarkar, MD David J. Kennedy, MD 2019 Program Co-chairs Alexander R. Vaccaro, MD, PhD 2020 Program Co-chairs Charles A. Reitman, MD Education Council Director Andrew Schoenfeld, MD E. Kano Mayer, MD Michael P. Steinmetz, MD 2021 Program Co-chairs

2020 Scientific Program Reviewers NASS thanks the following volunteers who spent numerous hours reviewing abstracts:

Bizhan Aarabi, MD, FACS, FRCSC H. Michael Guo, MD Charles A. Reitman, MD Amir Abthai, MD Richard D. Guyer, MD Evan W. Rivers, DO Owoicho Adogwa, MD, MPH Yong Hai, MD, PhD Robb Russell, DC Henry Ahn, MD, PhD, FRCSC Andrew C. Hecht, MD Byron J. Schneider, MD Mir H. Ali, MD, PhD Andrew C. Hsu, MD, MPH, MS Jerome Schofferman, MD Kristin Archer, PT, PhD Fan Jiang, MD Jacob Schwarz, MD Paul M. Arnold, MD Mike Kelly, MD Francis H. Shen, MD Jon Belding, MD Safdar Khan, MD W. Ryan Spiker, MD Carlo Bellabarba, MD David H. Kim, MD Michael Stauff, MD Sig H. Berven, MD Virginie Lafage, PhD Chris Steyn, MD Chris M. Bono, MD William LaVelle, MD Jeffrey A. Stone, MD, FACR Mohomad Bydon, MD Brandon Lawrence, MD Alison A. Stout, DO John A. Carrino, MD, MPH Stephen Lewis, MD Eric Sturos, MD Joseph S. Cheng, MD, MS Clifford Lin, MD Brian W. Su, MD Norman Chutkan, MD, FACS Allan R. Martin, MD Pradeep Suri, MD Andrew T. Dailey, MD E. Kano Mayer, MD Rajiv Taliwal, MD, MBA Russ DeMicco, DO Robert F. McLain, MD William C. Tally, MD Carrie A. Diulus, MD Hitesh Mehta, MD PhD Lee Tan, MD Reza Ehsanian, MD, PhD Hani Mhaidli, MD, PhD Tony Tannoury, MD Dennis E Enix, DC, MBA Michael W. Molter, DO Bobby Tay, MD Mark Erwin, DC, PhD Don K. Moore, MD Santhosh A. Thomas, DO, MBA Lisa A. Ferrara, PhD Isaac Moss, MD Eve Tsai-Ottawa, MD, PhD, FRCSC John C. France, MD Donald R. Murphy, DC Jed S. Vanichkachorn, MD, MBA, MHA Todd Francis, MD, PhD Brian J. Neuman, MD Franco Vigna, MD Jason Friedrich, MD Donna D. Ohnmeiss, MD Michael Vives, MD Anand Gandhi, MD Doug Orr, MD, FRCSC Jeffrey C. Wang, MD Marilyn Gates, MD, MBA Rick J. Placide, MD, PT Mike Wang, MD Howard Ginsberg, MD, FRCSC Adrian Popescu, MD Peter G. Whang, MD, FACS Vijay K. Goel, PhD Srini K. Prasad, MD Chris Witiw, MD Jonathan N. Grauer, MD Heidi Prather, DO Howard B. Yeon, MD, JD Carl Gregory, PhD Kris E Radcliff, MD Elizabeth Yu, MD Disclosure Policy Information 113

NASS Conflict of Interest Disclosure Program Committee Statement on Policy Resolution of Conflict of Interest in NASS is dedicated to offering high quality programming Presentations that is of the highest standards of academic rigor, The intent of this disclosure is to ensure that all conflicts intellectual veracity and professionalism. In order to of interest, if any, have been identified and have been achieve this goal, NASS has developed a Conflict of resolved prior to the speaker’s presentation. By doing so, Interest Disclosure Policy. A full version of this policy is the North American Spine Society has determined that available at: www.spine.org/DisclosurePolicy. The goal of the speaker’s or author’s interests or relationships have this policy is to create a uniform system that encourages not influenced the presentation with regard to exposition disclosures of situations in which there is even the or conclusion; nor does the Society view the existence of potential for bias, without any implications regarding these interests or commitments as necessarily implying actual bias. All authors and faculty speaking at the Annual bias or decreasing the value of the presentation. Meeting have been required to submit such disclosures. FDA Disclosure Commercial Support Disclosure If a device or drug requiring FDA approval is identified as As a sponsor accredited by the ACCME, the North an important component of a presentation, the author American Spine Society must ensure balance, must indicate the FDA status of those devices or drugs as independence, objectivity and scientific rigor in all its Approved, Investigational or Not Approved for distribution sponsored activities. All individuals participating in a within the United States. The Final Program and The Spine NASS-sponsored CME activity should disclose to the Journal Proceedings supplement will include all FDA audience all financial interests or other relationships with status information. Certain medical devices and drugs any commercial interest that occurred within the past identified at the Annual Meeting may have FDA clearance 12 months. Financial interests or other relationships for use for specific purposes only, or in restricted research may include grants or research support, employee, settings. The FDA has stated it is the responsibility of the consultant, major stockholder, member of the speaker’s physician to determine the FDA status of each drug or bureau, etc. Disclosure information is available visually device he or she wishes to use in clinical practice and to on a PowerPoint® slide before each presentation, in this use these products in compliance with applicable law. Final Program and in The Spine Journal Proceedings supplement. Note that audience members who volunteer questions or statements during symposia, focused Virtual Experience Disclosure discussions, or other educational events should disclose Availability their own conflicts to the assembled group before Disclosures are accessible in numerous places proceeding with their comments. throughout the Virtual Experience. Individual faculty disclosures are featured in their associated symposium. Abstract author disclosures are featured in each Learning Toolbox stack. All disclosures are also compiled in the Disclosure Index, available in the Research Library.