Datasheet FC02591-FITC Anti-Human CD13 Monoclonal Antibody

Product datasheet Anti-human CD13 Monoclonal Antibody FITC Conjugated, Flow Validated BOSTER BIOLOGICAL TECHNOLOGY Catalog Number: FC02591-FITC Special NO.1, International Enterprise Center, 2nd Guanshan Road, Wuhan, China

Web: www.boster.com.cn Phone: +86 27 67845390 Fax: +86 27 67845390 Email: [email protected]

Basic Information Product Name Anti-human CD13 Monoclonal Antibody FITC Conjugated, Flow Validated Gene Name ANPEP Source Mouse Species Reactivity human Tested Application Flow Cytometry Contents PBS with 0.09% NaN3 and 0.2% (w/v) BSA Immunogen Recombinant human CD13 protein Purification Observed MW Dilution Ratios User need to optimize the dilution ratio for this antibody

Storage 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing

Background Information Alanine aminopeptidase, also known as ANPEP or CD13. is an enzyme that is used as a biomarker to detect damage to the kidneys, and that may be used to help diagnose certain kidney disorders. It is mapped to 15q26.1. Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine, Aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases, and it is also thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Petrovic et al showed that CD13 was required for endothelial cell invasion in response to bradykinin. Inhibition of CD13 abrogated internalization of bradykinin receptor B2 and reduced endothelial cell motility.

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1 / 2 Product datasheet Anti-human CD13 Monoclonal Antibody FITC Conjugated, Flow Validated BOSTER BIOLOGICAL TECHNOLOGY Catalog Number: FC02591-FITC Special NO.1, International Enterprise Center, 2nd Guanshan Road, Wuhan, China

Web: www.boster.com.cn Phone: +86 27 67845390 Fax: +86 27 67845390 Email: [email protected]

Selected Validation Data

Lymphocytes gated PBMCs stained withFITC conjugated anti-human CD7 (clone4H9, red histogram). Lymphocytes gatedPBMCs stained with IgG2a FITC isotypecontrol (blue histogram).