Mckee CV 2016.November
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Disclosures Repetitive Head Impacts Subconcussive Trauma
5/2/2017 Chronic Traumatic Encephalopathy Harvard Dementia Course June 9, 2017 Robert A. Stern, PhD Professor of Neurology, Neurosurgery, and Anatomy & Neurobiology Clinical Core Director, BU Alzheimer’s Disease & CTE Center Boston University School of Medicine Disclosures • Psychological Assessment Resources, Inc. – Royalties for published tests • Avanir Pharmaceuticals – Consulting fees as member of TBI Advisory Board Member • Biogen – Consulting fees as member of Alzheimer’s Medical Advisory Board • King-Devick Test, Inc. – Stock options as member of Board of Directors • National Collegiate Athletic Association Student-Athlete Concussion Injury Litigation – Consulting fees as member of Medical Science Committee • Avid Radiopharmaceuticals – Research grant Repetitive Head Impacts Symptomatic mTBI/Concussion Subconcussive Trauma 1 5/2/2017 Subconcussive Impacts • Impact to brain with adequate force to have an effect on neuronal functioning (possibly including: neurometabolic cascade, neuroimmune response, breakdown of blood brain barrier) BUT… No Immediate Symptoms of Concussion • Some sports and positions very prone – Pro football linemen may have 1000-1500 of these hits per season, each at 20-30 g. Force = Mass x Acceleration •Athletes are getting bigger and faster! –Anzell et al., 2013 Subconcussive Impacts • Using helmet accelerometers, Broglio and colleagues (2011) found that high school football players received, on average, 652 hits to head in excess of 15 g of force. One player received 2,235 hits! Studies with college players -
Boxing Lessons: an Historical Review of Chronic Head Trauma in Boxing and Football,"
See discussions, stats, and author profiles for this publication at: https://www.researchgate.net/publication/235350692 “Boxing Lessons: An Historical Review of Chronic Head Trauma in Boxing and Football," Article · September 2012 CITATION READS 1 229 3 authors, including: Jason Shurley Jan S Todd University of Wisconsin - Whitewater University of Texas at Austin 8 PUBLICATIONS 8 CITATIONS 48 PUBLICATIONS 189 CITATIONS SEE PROFILE SEE PROFILE All in-text references underlined in blue are linked to publications on ResearchGate, Available from: Jan S Todd letting you access and read them immediately. Retrieved on: 21 November 2016 Kinesiology Review, 2012, 1, 170-184 © 2012 by Human Kinetics, Inc. Boxing Lessons: An Historical Review of Chronic Head Trauma in Boxing and Football Jason P. Shurley and Janice S. Todd In recent years there has been a significant increase in the scrutiny of head trauma in football. This attention is due largely to a host of studies that have been highly publicized and linked the repetitive head trauma in football to late-life neurological impairment. Scientists and physicians familiar with boxing have been aware of such impairment, resulting from repeated head impacts, for more than 80 years. Few, however, made the connection between the similarity of head impacts in boxing and football until recent decades. This article exam- ines the medical and scientific literature related to head trauma in both boxing and football, paying particular attention to the different emphases of that research. Further, the literature is used to trace the understanding of sport-related chronic head trauma as well as how that understanding has prompted reform efforts in each sport. -
Boston University and Department of Veterans Affairs Researchers Discover Brain Trauma in Sports May Cause a New Disease That Mimics Als
BOSTON UNIVERSITY AND DEPARTMENT OF VETERANS AFFAIRS RESEARCHERS DISCOVER BRAIN TRAUMA IN SPORTS MAY CAUSE A NEW DISEASE THAT MIMICS ALS Two former NFL players died after being diagnosed with Lou Gehrig’s Disease; New findings suggest they had a new disease associated with repetitive brain trauma (BOSTON) – The Center for the Study of Traumatic Encephalopathy (CSTE) at Boston University School of Medicine (BUSM) and Department of Veterans Affairs (VA) announced today that they have provided the first pathological evidence that repetitive head trauma experienced in collision sports is associated with motor neuron disease, a neurological condition that affects voluntary muscle movements. The most common form of motor neuron disease is amyotrophic lateral sclerosis (ALS) or Lou Gehrig’s disease. The findings will be published in the September issue of the Journal of Neuropathology and Experimental Neurology (http://journals.lww.com/jneuropath). The finding was discovered by Ann McKee, MD, and colleagues at the CSTE. McKee, a CSTE Co- Director, is an associate professor of neurology and pathology at BUSM, as well as Director of Neuropathology for the Department of Veterans Affairs at the Bedford VA Medical Center, where this research was conducted. McKee and the CSTE researchers made this groundbreaking pathological discovery while examining the brains and spinal cords of 12 athletes donated by family members to the CSTE Brain Bank at the Bedford VA Medical Center. Three of these 12 athletes, including former professional football players Wally Hilgenberg and Eric Scoggins, as well as an unidentified former military veteran and professional boxer, developed motor neuron disease late in their lives. -
Concussion! Friday Night Lights and Informed Consent—A Commentary
COMMENTARY Concussion! Friday Night Lights and Informed Consent—A Commentary a b KATHY A. DEBARR, PhD MICHELE L. PETTIT, MPH, PhD, MCHES Citation: DeBarr KA, Pettit ML. Concussion! Friday night lights and informed consent—a commentary. J Sch Health. 2019; 89: 341-344. DOI: 10.1111/josh.12744 Received on October 6, 2017 Accepted on August 21, 2018 ootball is a national pastime, and for many, an The US Centers for Disease Control and Prevention Fobsession. It also is an entertainment industry (CDC) has prioritized concussion, a medical condition tour de force with the National Football League (NFL) that requires a medical diagnosis and management, generating estimated revenues greater than $13 billion as an important public health issue with its online in 2016.1 The national culture of football perpetuated training module, Heads Up.7 According to the CDC: by the NFL trickles down to the state and local levels. ‘‘A concussion is a type of traumatic brain injury—or Inspired by this culture, roughly 3.5 million youth in TBI—caused by a bump, blow, or jolt to the head the United States play football and continue to play the or by a hit to the body that causes the head and game throughout high school.2 In fact, in cities and brain to move rapidly back and forth. This sudden small towns across the United States, autumn ushers movement can cause the brain to bounce around in the bright lights of Friday night high school football. or twist in the skull, stretching and damaging the Unfortunately, the excitement and thrill of the high brain cells and creating chemical changes in the school football season is not without consequence. -
Framing and News Coverage of the NFL's Concussion Lawsuit in The
A Hit to the Head: Framing and News Coverage of the NFL’s Concussion Lawsuit in The New York Times and ESPN ____________________________________ A Thesis Presented to the Honors Tutorial College Ohio University ____________________________________ In Partial Fulfillment of the Requirements for Graduation from The Honors Tutorial College with the degree of Bachelor of Science in Journalism ____________________________________ By Kaitlin Coward May 2018 2 This thesis has been approved by The Honors Tutorial College and the E.W. Scripps School of Journalism __________________________ Dr. Aimee Edmondson Associate Professor, Journalism Thesis Adviser ___________________________ Dr. Bernhard Debatin Director of Studies, Journalism ___________________________ Cary Frith Interim Dean, Honors Tutorial College 3 ACKNOWLEDGEMENTS This thesis would never have been possible without Dr. Aimee Edmondson and all the guidance she provided throughout the past year. She worked to guide me through my research, keep me calm when things got stressful and push me to make my writing the best it could be. I truly do not know how this project would have to come to be without her. Several other people have helped me along the process as well, including Dr. Bernhard Debatin, who initially approved the idea behind this. I also want to give a special shoutout to everyone in The Post newsroom for listening to me ramble about concussions and letting me talk people’s ears off about social responsibility theory and more. You all made it so I was consistently excited about my project and gave me the belief that I could actually do this. I also want to thank those of you who took the time to read through and copy edit my chapters. -
(Steele-Richardson-Olszewski Syndrome) and Clinical Predictors of Survival: a Clinicopathological Study
3'ournal ofNeurology, Neurosurgery, and Psychiatry 1996;61:615-620 615 Natural history of progressive supranuclear palsy J Neurol Neurosurg Psychiatry: first published as 10.1136/jnnp.60.6.615 on 1 June 1996. Downloaded from (Steele-Richardson-Olszewski syndrome) and clinical predictors of survival: a clinicopathological study I Litvan, C A Mangone, A McKee, M Veiny, A Parsa, K Jellinger, L D'Olhaberriague, K Ray Chaudhuri, R K B Pearce Abstract Keywords: progressive supranuclear palsy; natural his- Objective-To analyse the natural history tory; survival ofprogressive supranuclear palsy (PSP or Steele-Richardson-Olszewski syndrome) Progressive supranuclear palsy (PSP or Steele- and clinical predictors of survival in 24 Richardson-Olszewski syndrome) causes patients with PSP confirmed by necropsy, postural instability, supranuclear vertical oph- who fulfilled the NINDS criteria for a thalmoplegia, parkinsonism unresponsive to neuropathological diagnosis of typical levodopa, pseudobulbar palsy, and mild PSP. dementia.' 2 However, patients with PSP with- Methods-Patients were selected from the out ophthalmoplegia or dementia, or present- research and clinical files of seven med- ing only with dementia or akinesia, have also ical centres involving tertiary centres of been reported.3-7 Austria, England, France, and the United In the absence of laboratory markers for the States. Clinical features were analysed in diagnosis of PSP, neuropathological examina- Neuroepidemiology detail. The patients' mean age at onset of tion remains the "gold standard" -
Other Stakeholders
None - Stakeholders in NFL Player Health Report draft pg 49 Protecting and Promoting the THE MEDICAL TEAM Health of NFL Players: Legal and Ethical Analysis and Recommendations Club Athletic Second Neutral Personal Doctors Trainers Opinion Doctors Doctors Doctors Retained by Club THE NFL, NFLPA, and NFL CLUBS NFL CLUB EMPLOYEES NFL NFLPA NFL Coaches Club Equipment Clubs Employees Managers Part 6: Other Stakeholders PLAYER ADVISORS OTHER STAKEHOLDERS Contract Financial Family Officials Equipment Media Fans NFL Advisors Advisors Mfrs. Business (Agents) Partners OTHER INTERESTED PARTIES Christopher R. Deubert NCAA Youth Govern- Workers’ Health- I. Glenn Cohen Leagues ment Comp. related Attys Companies Holly Fernandez Lynch Petrie-Flom Center for Health Law Policy, Biotechnology, and Bioethics Harvard Law School Part 6 discusses several other stakeholders with a variety of roles in player health, including: Officials; Equipment Manufacturers; The Media; Fans; and, NFL Business Partners. Additionally, we remind the reader that while we have tried to make the chapters accessible for standalone reading, certain background or relevant information may be contained in other parts or chapters, specifically Part 1 discussing Players and Part 3 discussing the NFL and the NFLPA. Thus, we encourage the reader to review other parts of this Report as needed for important context. Chapter 15 Officials Officials, as the individuals responsible for enforcing the Playing Rules, have an important role in protecting player health on the field. In order to ensure that this chapter was as accurate and valuable as possible, we invited the National Association of Sports Officials (NASO) and the National Football League Referees Association (NFLRA), both described below, to review a draft version of this chapter prior to publication. -
Regulating the NFL's Concussion Policy Under the Commerce Clause
Concussion Crisis: Regulating the NFL’s Concussion Policy Under the Commerce Clause by MARGARET GREER* The NFL sort of reminds me of the tobacco companies, pre-’90s, when they kept saying, “no, there is no link between smoking and damage to your health.” -Representative Linda Sanchez (D), California Introduction The United States government’s interest in regulating and monitoring football head injuries dates back to the early twentieth century. In 1905, eighteen collegiate athletes died from football related injuries.1 With university presidents calling for the abolition of the game, President Theodore Roosevelt intervened in order to save the sport and to encourage the implementation of rules meant to reduce the risk of injury and death.2 At the emergency White House summit, representatives of the country’s top collegiate programs legalized the forward pass and increased the yardage required for a first down to ten yards in an attempt to deemphasize repeated tackling.3 The health and injury risks associated with football decreased even more when the National Football League (“NFL” or “League”), founded in 1920, made helmets mandatory in 1943.4 The introduction of high-strength thermoplastic helmets in the mid-1950s * J.D. Candidate 2015, University of California, Hastings College of the Law; B.A. 2011, University of California, Berkeley, History. The author would like to thank the editors of Hastings Constitutional Law Quarterly for their hard work and her parents and family for their continued support. 1. MARK FAINARU-WADA & STEVE FAINARU, LEAGUE OF DENIAL: THE NFL, CONCUSSIONS, AND THE BATTLE FOR TRUTH 135 (2013). 2. -
View Dr. Ann Mckee's CV
CURRICULUM VITAE Ann C. McKee, M.D. WEBSITES: http://www.bu.edu/cste, www.bu.edu/alzresearch ACADEMIC TRAINING: 1975 B.S. University of Wisconsin, Madison, Wisconsin 1979 M.D. Case Western Reserve School of Medicine, Cleveland, Ohio POSTDOCTORAL TRAINING: 1979 -1980 Intern in Internal Medicine, Cleveland Metropolitan General Hospital 1980 - 1981 Junior Assistant Resident in Internal Medicine, Cleveland Metropolitan General Hospital 1981 -1982 Senior Assistant Resident in Internal Medicine and Junior Assistant Resident in Neurology, Cleveland Metropolitan General Hospital 1982 -1983 Senior Assistant Resident in Neurology, Cleveland Metropolitan General Hospital 1983 - 1984 Chief Resident in Neurology and Neuropathology, Cleveland Metropolitan General 1984 - 1985 Fellow in the Neurology of Aging, University of Massachusetts Medical Center 1986 - 1988 Chief Resident in Neuropathology, Massachusetts General Hospital 1988 - 1989 Resident in Pathology, Massachusetts General Hospital ACADEMIC APPOINTMENTS: 1984 - 1985 Clinical Fellow in Neurology, University of Massachusetts Medical Center 1986 - 1989 Clinical Fellow in Neuropathology (Pathology), Harvard Medical School 1989 - 1991 Instructor in Neuropathology (Pathology), Harvard Medical School 1991 - 1994 Assistant Professor in Neuropathology (Pathology), Harvard Medical School 1994 - 2011 Associate Professor in Neurology & Pathology, Boston University School of Medicine 2011 - Professor in Neurology & Pathology, Boston University School of Medicine HOSPITAL APPOINTMENTS: 1991 - 1994 Assistant -
Running Head: TACKLING DISEASE and DENIALS
Running Head: TACKLING DISEASE AND DENIALS Tackling disease and denials: The image repair strategies of the National Football League’s response to CTE and concussions by Logan Patrick Barrett A thesis submitted to the Graduate Faculty of Auburn University in partial fulfillment of the requirements for the Degree of Master of Arts Auburn, Alabama May 3, 2020 Keywords: Image Restoration, NFL, Concussions, Football, Image Repair, CTE Copyright 2020 by Logan Patrick Barrett Approved by Dr. John Carvalho, Professor, Communication and Journalism Dr. Diana Sisson, Assistant Professor, Communication and Journalism Dr. Michael Milford, Associate Professor, Communication and Journalism TACKLING DISEASE AND DENIALS 2 Abstract This study discusses the National Football League’s (NFL) response campaign to concussions and chronic traumatic encephalopathy (CTE) primarily focusing on the response during the tenure of NFL Commissioner Roger Goodell. This is a relevant topic due to the massive following of professional football and the economic and cultural impact that the sport of football possesses. This study uses William Benoit’s Theory of Image Restoration (1995) and its strategies to evaluate the different aspects of the NFL’s campaign. To do this as accurately and as detailed as possible, this study will split the NFL’s campaign into three prongs: the communicative, the programs and initiatives, and the investments in research. The research questions address the strategies used in each of the prongs individually and collectively and contrasts which strategies were used in each prong. Multiple levels of coding were done on several different items to develop a better idea of what strategies were used and why. -
Brogley Webb 1 Concussions and Other Headaches
Brogley Webb 1 Concussions and Other Headaches: An Analysis of the Journalistic Coverage of the Concussion Crisis and Football-Related Brain Trauma _________________________________ A Thesis Presented to The Honors Tutorial College Ohio University ________________________________________________ In Partial Fulfillment of the Requirements for Graduation from The Honors Tutorial College with the degree of Bachelor of Science in Journalism __________________________________ By Jordan Brogley Webb April 2014 Brogley Webb 2 This thesis has been approved by The Honors Tutorial College and the Department of Journalism Ohio University _________________________ Professor Thomas Hodson Thesis Advisor Professor, Journalism _________________________ Dr. Bernhard Debatin Honors Tutorial College Director of Studies, Journalism _________________________ Dr. Jeremy Webster Dean, Honors Tutorial College Brogley Webb 3 ACKNOWLEDGEMENTS This thesis would not have been possible about the care and guidance of many individuals. First and foremost I would like to thank my parents, Douglas Webb and Joycelyn Brogley for all of their love and for giving me the opportunity to pursue my journalism degree in a world-renowned institution like Scripps and the Honors Tutorial College. Their pursuits and passions for careers and medicine and law have inspired a great deal of my thesis. Thank you to Dr. Michael Butterworth, Dr. Julia Keller, Dr. Brian Ragan, Dr. Craig Chappell, Dr. Aimee Edmondson, and Bill Reader, for their help in my research. To my fellow HTC journalism senior, roommate, and best friend, Maggie Krueger, I thank you for tremendous support of me throughout this entire process. I never would have seen this project through if it were not for her help on numerous aspects of it. -
A Media Analysis of Concussion Terminology in Documentary Film
Name of the Game: A Media Analysis of Concussion Terminology in Documentary Film BY Kaitlyn Graham ADVISOR • Julie Volkman EDITORIAL REVIEWER • Judith McDonnell _________________________________________________________________________________________ Submitted in partial fulfillment of the requirements for graduation with honors in the Bryant University Honors Program May 2018 Name of the Game: A Media Analysis of Concussion Terminology in Documentary Film Senior Capstone Project for Kaitlyn Graham Table of Contents Abstract……………………………………………………………………………………………………………………………………. 2 Introduction……………………………………………………………………………………………………………………………… 3 Rationale………………………………………………………………………………………………………………………. 4 Research Questions………………………………………………………………………………………………………. 6 Limitations……………………………………………………………………………………………………………………………….. 7 Methodology……………………………………………………………………………………………………………………………. 9 Literature Review…………………………………………………………………………………………………………………… 11 Concussions………………………………………………………………………………………………………………… 12 Media Analysis……………………………………………………………………………………………………………. 18 Results……………………………………………………………………………………………………………………………………. 24 Discussion………………………………………………………………………………………………………………………………. 28 Errors………………………………………………………………………………………………………………………….. 40 Conclusion……………………………………………………………………………………………………………………………… 41 References……………………………………………………………………………………………………………………………… 45 Appendix…................................................................................................................................... 49 1 Name of the Game: A Media Analysis