WNK3 Antibody Cat. No.: 62-623

WNK3 Antibody

WNK3(PRKWNK3) Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human

This WNK3 (PRKWNK3) antibody is generated from rabbits immunized with a KLH IMMUNOGEN: conjugated synthetic peptide between 1586-1616 amino acids from the C-terminal region of human WNK3 (PRKWNK3).

TESTED APPLICATIONS: IHC-P, WB

For WB starting dilution is: 1:1000 APPLICATIONS: For IHC-P starting dilution is: 1:10~50

PREDICTED MOLECULAR 198 kDa WEIGHT:

September 24, 2021 1 https://www.prosci-inc.com/wnk3-antibody-62-623.html Properties

This antibody is purified through a protein A column, followed by peptide affinity PURIFICATION: purification.

CLONALITY: Polyclonal

ISOTYPE: Rabbit Ig

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.

CONCENTRATION: batch dependent

Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies STORAGE CONDITIONS: care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Additional Info

OFFICIAL SYMBOL: WNK3

Serine/threonine-protein kinase WNK3, Protein kinase lysine-deficient 3, Protein kinase ALTERNATE NAMES: with no lysine 3, WNK3, KIAA1566, PRKWNK3

ACCESSION NO.: Q9BYP7

PROTEIN GI NO.: 353526307

GENE ID: 65267

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

Members of the 'with no lysine' (WNK) kinase family, such as WNK3, are serine-threonine protein kinases that lack the almost invariant catalytic lysine in subdomain II, which is BACKGROUND: important for binding ATP in the catalytic site. Instead, these kinases have a conserved lysine in subdomain I that is thought to provide this function (Holden et al., 2004 [PubMed 15194194]).[supplied by OMIM]

REFERENCES: 1) Verissimo, F., et al., Oncogene 20(39):5562-5569 (2001).

2) Nagase, T., et al., DNA Res. 7(4):273-281 (2000).

ANTIBODIES FOR RESEARCH USE ONLY.

For additional information, visit ProSci's Terms & Conditions Page.

September 24, 2021 2 https://www.prosci-inc.com/wnk3-antibody-62-623.html