DDX19B Antibody Cat. No.: 29-251

DDX19B Antibody

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Dog, Human, Mouse, Rat, Zebrafish

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region IMMUNOGEN: of human DDX19B.

TESTED APPLICATIONS: ELISA, WB

DDX19B antibody can be used for detection of DDX19B by ELISA at 1:62500. DDX19B APPLICATIONS: antibody can be used for detection of DDX19B by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

POSITIVE CONTROL: 1) Cat. No. 1211 - HepG2 Cell Lysate

PREDICTED MOLECULAR 53 kDa, 42 kDa, 50 kDa, 54 kDa WEIGHT:

Properties

PURIFICATION: Antibody is purified by A chromatography method.

CLONALITY: Polyclonal

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

October 6, 2021 1 https://www.prosci-inc.com/ddx19b-antibody-29-251.html Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% BUFFER: sucrose.

CONCENTRATION: batch dependent

For short periods of storage (days) store at 4˚C. For longer periods of storage, store STORAGE CONDITIONS: DDX19B antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Additional Info

OFFICIAL SYMBOL: DDX19B

ALTERNATE NAMES: DDX19B, DBP5, RNAh, DDX19

ACCESSION NO.: NP_009173

PROTEIN GI NO.: 6005743

GENE ID: 11269

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

DEAD box , characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA . They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and and assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX19B is a DEAD box protein, which exhibits RNA-dependent ATPase and ATP-dependent RNA-unwinding activities. This protein is recruited to the cytoplasmic fibrils of the complex, where it participates in the export of mRNA from the nucleus.DEAD box proteins, BACKGROUND: characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This encodes a DEAD box protein, which exhibits RNA-dependent ATPase and ATP-dependent RNA-unwinding activities. This protein is recruited to the cytoplasmic fibrils of the nuclear pore complex, where it participates in the export of mRNA from the nucleus. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

REFERENCES: 1) Yin, L., Reprod. Fertil. Dev. 14 (3-4), 185-189 (2002).

ANTIBODIES FOR RESEARCH USE ONLY.

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