Product Datasheet

IL12A Antibody

Catalog No: #40406

Orders: [email protected] Description Support: [email protected]

Product Name IL12A Antibody

Host Species Rabbit

Clonality Polyclonal

Purification Antigen affinity purification.

Applications IHC

Species Reactivity Hu

Specificity The antibody detects endogenous levels of total IL12A protein.

Immunogen Type Peptide

Immunogen Description Synthetic peptide of human interleukin 12A

Target Name IL12A

Other Names P35; CLMF; NFSK; NKSF1; IL-12A

Accession No. Swiss-Prot:P29459Gene Accssion:NP_000873

Concentration 1.2mg/ml

Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage Store at -20°C

Application Details

Immunohistochemistry:1:10-1:50

Images

Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using #40406 at dilution 1/20.

Address: 8400 Baltimore Ave., Suite 302, College Park, MD 20740, USA http://www.sabbiotech.com 1 Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissue using #40406 at dilution 1/20.

Background

This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity.

Note: This product is for in vitro research use only and is not intended for use in humans or animals.

Address: 8400 Baltimore Ave., Suite 302, College Park, MD 20740, USA http://www.sabbiotech.com 2