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TDRKH polyclonal antibody

Catalog: BS8424 Host: Rabbit Reactivity: Human,Mouse,Rat

BackGround: The antibody was affinity-purified from rabbit antiserum TDRKH (tudor and KH domain-containing ), also by affinity-chromatography using epitope-specific im- known as TDRD2 (tudor domain-containing protein 2), is munogen and the purity is > 95% (by SDS-PAGE). a 561 amino acid protein that contains two KH domains Applications: and one tudor domain. TDRKH exists as two alternatively WB: 1:500~1:2000 spliced isoforms and interacts with HIWI and HILI2. The Storage&Stability: that encodes TDRKH contains roughly 21,310 bases Store at 4°C short term. Aliquot and store at -20°C long and maps to human 1q21. With roughly term. Avoid freeze-thaw cycles. 3,000 that span about 260 million base pairs, Specificity: makes up approximately 8% of the human TDRKH polyclonal antibody detects endogenous levels genome. There are also a large number of diseases asso- of TDRKH protein. ciated with chromosome 1, notably, the rare aging disease DATA: Hutchinson-Gilford progeria which is associated with the LMNA gene that encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome,

Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. Western blot analysis of extracts of various cell lines, using TDRKH Product: antibody. Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, Note: 50% glycerol, pH7.2 For research use only, not for use in diagnostic procedure. Molecular Weight: ~ 72 kDa Swiss-Prot: Q9Y2W6 Purification&Purity:

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