Program Guide

2011 Drosophila Meeting Orgaanizers Daniel Barbash Giovanni Bosco Leslie Griffith

2010/2011 Drosophila Board of Directors Officers President Denise Montell President-Elect Elizabeth Gavis Past-President Terry Orr-Weaver Past-President Utpal Banerjee Past-President & Elections Chair Carl Thummel Treasurer Pam Geyer

Regional Representatives International Representatives Canada Helen McNeil Australia/Oceana Helena Richardson Great Lakes A. Javier Lopez Asia Henry Sun Northwest Hannele Ruohola-Baker Europe Michael Boutros Southeast Jeff Sekelsky Latin America Juan Riesgo-Escovar California Michelle Arbeitman Heartland Janice Fischer Primary Undergraduate Institution New England Leslie Griffith Representative Mid-Atlantic Nancy Bonini Karen Hales Midwest Tom Neufeld

Sponsored by: The Genetics Society of America 9650 Rockville Pike, Bethesda, Maryland 20814-3998 Telephone: (301) 634-7300 • Fax: (301) 634-7079 E-mail: [email protected] • Web site: genetics-gsa.org

GRAND SPONSOR The Genetics Society of America

EVENT SPONSOOR

Genetic Services Inc. – Sponsor of the Refreshment Break on Thursdaay, March 31.

Table of Contents

Schedule of Events ...... 5

Maps

Town and Country Resort & Conference Center ...... 12 Posters and Exhibits ...... 13

General Information ...... 14

Awards Larry Sandler Memorial Lecture ...... 18 Poster Award Competition ...... 18 The DeLill Nasser Award for Professional Development in Genetics ...... 19

Exhibits ...... 20

Opening General Session and Plenary Sessions ...... 23

Workshops ...... 25

Concurrent Platform Sessions ...... 30

Poster Sessions ...... 44

Speaker and Author Index ...... 84

Keyword Index...... 108

Flybase Genetic Index to Abstracts ...... 114

Future Meeting Dates

2012 2014 2016 March 7-11 March 26-30 March 2-6 Chicago, IL San Diego, CA Philadelphia, PA

2013 2015 April 3-7 March 4-8 Washington, DC Chicago, IL

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Schedule of Events

WEDNESDAY, March 30

12:00 pm - 6:00 pm Ecdysone Workshop Pacific Salon 2/3 Organizers: Christen Mirth, Instituto Gulbenkian de Ciencia; and Arash Bashirullah, University of Wisconsin 3:00 pm - 6:30 pm Speaker Ready Room Terrace Salon 3 All speakers must upload their presentations the day before their session and check in at the Speaker Ready Room 3:00 pm - 6:00 pm Drosophila Board of Directors Meeting Pacific Ballroom Salon 1 3:30 pm - 9:00 pm Registration and Book/T-Shirt Pickup Open Atlas Foyer 5:00 pm - 12:00 am Posters Open Grand Exhibit Hall 5:30 pm - 7:00 pm Undergraduate Student Mixer Tiki Pavilion By invitation only

7:00 pm - 9:15 pm Opening General Session Atlas Ballroom 7:00 pm Welcome and Opening Remarks

Giovanni Bosco, University of Arizona, Tucson 7:10 pm GSA Update 7:15 pm Larry Sandler Award Presentation

Allison Bardin, Curie Institute, Paris, France 7:20 pm Larry Sandler Lecture 8:05 pm Historical Lecture Introduction

Leslie Griffith, Brandeis University, Waltham, MA 8:10 pm Historical Lecture. Featuring featuring Stephen Goodwin, Ulrike Heberlein, Michael Rosbash and Scott Waddell Michael Rosbash, Moderator, Brandeis University, Waltham, MA 9:10 pm GSA Award Presentation - Congratulations to John Carlson

R. Scott Hawley, Stowers Institute for Medical Research, Kansas City, MO

9:15 pm - 11:00 pm Mixer/Reception Grand Plaza

Schedule of Events

THURSDAY, March 31

1:00 am - 12:00 am Posters Open Grand Exhibit Hall Posters Open for Viewing 24 Hours 7:00 am - 3:00 pm Speaker Ready Room Terrace Salon 3 All speakers must upload their presentations the day before their session and check in at the Speaker Ready Room 7:15 am - 8:30 am Continental Breakfast Atlas Foyer 8:00 am - 5:00 pm Registration and Book/T-Shirt Pickup Open Atlas Foyer

8:30 am - 10:00 am Plenary Session I Atlas Ballroom Moderator: Daniel Barbash, Cornell University, Ithaca, NY 8:30 am Image Award Presentation Michelle Arbeitman, University of Southern California, Los Angeles 8:35 am Ageing Flies Linda Partridge, Gen, Evolution & Environment, University College London, United Kingdom 9:00 am From the Cambrian to the Sushi Bar: TRPA1 and the Evolution of Thermal and Chemical Sensing

Paul A. Garrity, National Center for Behavioral Genomics, Brandeis Univ, Waltham, MA 9:30 am Pleiotropy, Environment, and Non-Immunological Determinants of Defense Against Infection in

Drosophila Brian P. Lazzaro, Cornell University, Ithaca, NY

8:30 am - 12:30 pm GSA Undergraduate Experience Royal Palm This session provides students (and their professors) from Ballroom 5 genetics classes at local undergraduate institutions with the opportunity to observe distinguished career scientists present their current research in a conference setting. Invitation only. 10:00 am - 10:30 am Refreshment Break Sponsored by Genetic Services Atlas Foyer Inc (booth #113) 10:00 am - 4:00 pm FlyMine Demonstrations Royal Palm Ballroom 4 Presentations:

1:00-1:20 pm: FlyMine 1:30-1:50 pm: modENCODE

3:00-3:20 pm: FlyMine 3:30-3:50 pm: modENCODE

Schedule of Events

10:30 am - 12:00 pm Plenary Session I (continued) Atlas Ballroom

10:30 am Genetic Analysis of Vesicle Movement Lawrence S. B. Goldstein, University of California, San Diego 11:00 am Contrasting Patterns of Polymorphism and Divergence in the Evolution of Gene Expression Patricia J. Wittkopp, University of Michigan, Ann Arbor 11:30 am Chromosomal Organization of Drosophila melanogaster Genome Igor F. Zhimulev, Inst Chemical Biology & Fundamental Medicine, Novosibirsk, Russian Federation; Department of Molecular and Cellular Biology

12:45 pm - 1:45 pm GSA Career Luncheon Pacific Ballroom Salon 3 1:00 pm - 5:00 pm FlyBase Demo Room Open for Tutorials & Royal Palm Discussions Ballroom 1-3

Presentations:

2:00-2:15 pm: Community Curation in FlyBase 2:20-2:35 pm: Navigating Expression Data in FlyBase

2:00 pm - 4:00 pm Exhibits Open & Poster Presentations Grand Exhibit Hall 2:00 pm-3:00 pm Even-Numbered Poster Authors 3:00 pm-4:00 pm Odd-Numbered Poster Authors

Poster Viewing Open 24 Hours 4:30 pm - 6:30 pm Concurrent Platform Session

Cell Division & Growth Control Town & Country RNA Biology Golden West Neurogenetics and Neural Development California 6:30 pm - 7:30 pm Education SIG Mixer Tiki Pavilion Open to PIs (only) who are interested in getting more involved in educational programming and resource development at GSA. Contact Beth Ruedi at [email protected] for more information. 8:00 pm - 11:00 pm Exhibits Open & Poster Viewing Grand Exhibit Hall

Schedule of Events

FRIDAY, April 1

1:00 am - 12:00 am Posters Open Grand Exhibit Hall Posters Open for Viewing 24 Hours 7:00 am - 3:00 pm Speaker Ready Room Terrace Salon 3 All speakers must upload their presentations the day before their session and check in at the Speaker Ready Room 8:30 am - 5:00 pm Registration and Book/T-Shirt Pickup Open Atlas Foyer 8:30 am - 10:15 am Concurrent Platform Sessions

Evolution and Quantitative Genetics Town & Country Drosophila Models of Human Disease Golden West Pattern Formation California 10:00 am - 4:00 pm FlyMine Demonstrations Royal Palm Ballroom 4 Presentations:

1:00-1:20 pm: FlyMine 1:30-1:50 pm: modENCODE

3:00-3:20 pm: FlyMine 3:30-3:50 pm: modENCODE 10:15 am - 10:45 am Refreshment Break Atlas Foyer 10:45 am - 12:30 pm Concurrent Platform Sessions

Cell Cycle and Cell Death California Evolution and Quantitative Genetics (continued) Town & Country Drosophila Models of Human Disease (continued) Golden West 1:00 pm - 5:00 pm FlyBase Demo Room Open for Tutorials & Royal Palm Discussions Ballroom 1-3

Presentations:

3:45-4:00 pm: Navigating Expression Data in FlyBase 4:05-4:20 pm: Community Curation in FlyBase 1:45 pm - 3:45 pm Concurrent Workshops

Cell Competition Pacific Ballroom Organizers: Wu-Min Deng, Florida State University; Salon 2 Tatsushi Igaki, Kobe Univeristy; and Eduardo Moreno, CNIO Apoptosis, Autophagy and Other Cell Death Pacific Ballroom Mechanisms Salon 3 Organizers: Andreas Bergman, MD Anderson Cancer Center; and Eli Arama, Weizmann Institute Chemical Genetics and Drug Screening Pacific Ballroom Organizers: Tin Tin Su, University of Colorado; and Salon 7 Claudio Sunkel, IBMC

Schedule of Events

Mechanisms and Functions of Chromosome Pairing Pacific Ballroom Organizers: Jeff Sekelsky, University of North Carolina; Salons 4-5 and Giovanni Bosco, University of Arizona 2:00 pm - 4:00 pm Dedicated Exhibit Time Grand Exhibit Hall 4:30 pm - 6:30 pm Concurrent Platform Sessions

Neural Physiology and Behavior Town & Country Chromatin and Epigenetics Golden West Cell Biology and Cytoskeleton California 8:00 pm - 11:00 pm Exhibits Open & Poster Presentations Grand Exhibit Hall 8:00 pm-9:00 pm "C" Poster Authors 9:00 pm-10:00 pm "B" Poster Authors 10:00 pm-11:00 pm "A" Poster Authors

Poster Viewing Open 24 Hours

Schedule of Events

SATURDAY, April 2

1:00 am - 10:00 pm Posters Open Grand Exhibit Hall 7:00 am - 3:00 pm Speaker Ready Room Terrace Salon 3 All speakers must upload their presentations the day before their session and check in at the Speaker Ready Room 8:30 am - 3:00 pm Registration and Book/T-Shirt Pickup Open Atlas Ballroom 8:30 am - 10:15 am Concurrent Platform Sessions

Gametogenesis and Organogenesis Town & Country Regulation of Gene Expression Golden West Immunity and Pathogenesis California 10:00 am - 4:00 pm FlyMine Demonstrations Royal Palm Ballroom 4 Presentations:

1:00-1:20 pm: FlyMine 1:30-1:50 pm: modENCODE

3:00-3:20 pm: FlyMine 3:30-3:50 pm: modENCODE 10:15 am - 10:45 am Refreshment Break Atlas Foyer 10:45 am - 12:30 pm Concurrent Platform Sessions

Physiology and Aging California Gametogenesis and Organogenesis (continued) Town & Country Regulation of Gene Expression (continued) Golden West 1:30 pm - 3:30 pm Exhibits Open & Poster Presentations Grand Exhibit Hall 1:30 pm-2:30 pm Odd-Numbered Poster Authors 2:30 pm-3:30 pm Even-Numbered Poster Authors

Poster Viewing Open 24 Hours

4:00 pm - 6:00 pm Concurrent Platform Sessions

Techniques and Functional Genomics Town & Country Stem Cells Golden West Cell Biology and Signal Transduction California 6:45 pm - 8:45 pm Concurrent Workshops

Confocal Imaging Pacific Ballroom Organizer: Steve Paddock, HHMI/University of Salon 2 Wisconsin Drosophila Research and Pedagogy at Primarily Pacific Ballroom Undergraduate Institutions (PUI) Salon 1 Organizers: Jason Duncan, Willamette University; Janet Rollins, College of Mount Saint Vincent; and Thomas M

Schedule of Events

Onorato, Laguardia Community College/CUNY Quantitative Biology of Cell Signaling and Pattern Pacific Ballroom Formation Salons 4-5 Organizers: David Arnosti, Michigan State University; and Stas Shvartsman, Princeton University Emerging Model Arthropods Pacific Ballroom Organizer: Molly Duman-Scheel, Indiana University Salon 3 School of Medicine Everything You Ever Wanted to Know About Sex Pacific Ballroom Organizer: Mark Van Doren, Johns Hopkins University Salons 6-7 7:00 pm - 10:00 pm Exhibits Open & Poster Viewing Grand Exhibit Hall 9:00 pm - 11:00 pm modENCODE Workshop Atlas Ballroom Organizers: Susan Celniker, Lawrence Berkeley National Laboratory; and Gary Karpen, Lawrence Berkely National Laboratory

SUNDAY, April 3

8:30 am - 12:00 pm Plenary Session II Atlas Ballroom Moderator: Giovanni Bosco, University of Arizona, Tucson 8:30 am Poster Award Presentation

Giovanni Bosco, University of Arizona, Tucson 8:35 am Nucleosome Dynamics and Gene Regulation

Kami Ahmad, Harvard Medical School, Boston, MA 9:00 am The Secret Lives of Flies: What Nature Means for the Laboratory Therese A. Markow, University of California, San Diego 9:30 am Autoregulatory and Paracrine Control of Synaptic and Behavioral Plasticity by Octopaminergic Signaling Vivian Budnik, Neurobiology, University of Massachusetts Medical School, Worcester 10:00 am Break 10:30 am Biogenesis and Function of microRNAs

Eric C. Lai, Sloan Kettering Institute, NY 11:00 am Understanding the 'Why?': Evolution of Behavior in Social Insects Anna Dornhaus, University of Arizona, Tucson 11:30 am The Mechanics of Shape Change in the Drosophila Embryo Eric F. Wieschaus, HHMI, Department of Molecular Biology, Lewis-Sigler Institute for Integrative Genomic, Princeton University, NJ

General Information

Badges Badges are required for admission to all sessions, the opening mixer, and the posters and exhibits in the Exhibition Hall. Security officers will not allow individuals without badges to enter the Exhibition Hall. If you lose your badge, a replacement may be requested at the Registration and Information Counters during posted registration hours. Badges may not be used by anyone other than the registered attendee. Each attendee must have his/her own badge.

Employment Opportunities/Seeking Employment Notices – Convention Registration Desk Individuals and institutions offering or seeking employment may post notices and résumés on the "Employment Opportunities" bulletin boards set up near the Registration and Information Counters on the lobby level at the Convention Registration Desk. Be sure to stop by the Convention Registration Desk and ask about the new Career Center now online at www.genetics-gsa.org

FlyBase Demonstrations – Royal Palms Salons 1-3 FlyBase invites all Conference registrants to come to the demo room to learn how to make the best use of the new FlyBase tools and features for your research and teaching. Throughout the day, other than the scheduled group presentations noted below, FlyBase personnel are available in the demo room for one-on-one tutorials, troubleshooting and discussions. Any thoughts on improvements we can make to FlyBase are gratefully appreciated.

Thursday, March 31 1:00 pm–5:00 pm Demo room open for tutorials and discussions

Presentations: 2:00 pm-2:15 pm: Community Curation in FlyBase 2:20 pm-2:35 pm: Navigating Expression Data in FlyBase

Friday, April 1 11:00 am–5:00 pm Demo room open for tutorials and discussions

Presentations: 3:45 pm-4:00 pm: Navigating Expression Data in FlyBase 4:05 pm-4:20 pm: Community Curation in FlyBase

FlyMine Demonstrations – Royal Palms Salon 4 FlyMine is an integrated database of genomics and proteomics data for Drosophila and other insects. modENCODE (model organism ENCyclopedia Of DNA Elements) is a project designed to identify the sequence-based functional elements in D. melanogaster and C. elegans. Explore how you can easily run a range of searches across these databases, construct your own data mining searches, upload and analyse your own experimental results and view and download large datasets.

Thursday, March 31-Saturday, April 2

10:00 am - 4:00 pm Demo room open for tutorials and discussions

Talks will take place daily, at the following times:

1:00 pm - 1:20 pm: FlyMine 1:30 pm - 1:50 pm: modENCODE

3:00 pm - 3:20 pm: FlyMine 3:25 pm - 3:45 pm: modENCODE

General Information

GSA Career Luncheon – Pacific Ballroom Salon 1 This session will be held on Thursday, March 31 from 12:45 to 1:45 pm. Principal investigators will be available to discuss their work and give valuable advice and input on career opportunities. For interested graduate and postdocs. Fee. Limited Attendance.

GSA Undergraduate Experience The GSA Undergraduate Experience provides students from genetics classes at local undergraduate institutions with the unique opportunity to observe distinguished career scientists present their current research in a conference setting. The students, accompanied by their professors, will receive a background lecture and participate in an interactive discussion before attending part of a plenary session. This informative and engaging program is meant to give students a glimpse into the real world of genetic research. Participation is by invitation only.

Internet Access – Conference Center Complimentary wireless high speed internet access is available in the Atlas Ballroom foyer.

Meals Please note that two meals are included in the meeting registration: the Opening Mixer on Wednesday night (with heavy hors d’oeuvres and a cash bar) and the Continental Breakfast on Thursday morning. All other meals are not included in your conference registration. For all other meals you may choose from options within the hotel (including grab-and-go food kiosks located in the meeting area for breakfast and lunch) or at nearby locations. Fashion Valley Shopping Center is conveniently located via footbridge behind the Royal Palm Tower and features fast food and a variety of restaurants.

Message Boards – Convention Registration Area Message boards will be located near the Registration and Information Counters.

Parking Parking is available at the Town & Country Resort & Conference Center at a rate of $8 per day.

General Information

Poster Sessions and Exhibits – Grand Exhibit Hall All posters will be displayed in the Grand Exhibit Hall. The Hall will be open to Conference registrants on a 24-hour basis beginning at 5:00 pm, Wednesday, March 30, until 10:00 pm, Saturday, April 2. Security will be posted at the entrance to the Hall and only individuals with official Drosophila Conference registration badges will be admitted. All attendees are responsible for their own personal items and should not leave things unattended. Guest pass applications may be made at the registration counter during regular registration hours.

Exhibit representatives will be in their booths: Thursday, March 31: 2:00 pm–4:00 pm and 8:00 pm–11:00 pm Friday, April 1: 2:00 pm–4:00 pm and 8:00 pm–11:00 pm Saturday, April 2: 1:30 pm–3:30 pm and 7:00 pm–10:00 pm

Authors are expected to be present at their boards according to the following schedule: Thursday, March 31: 2:00 pm–3:00 pm Even-Numbered Posters 3:00 pm–4:00 pm Odd-Numbered Posters 8:00 pm–11:00 pm Open Poster Viewing (Authors not required to be present)

Friday, April 1 2:00 pm–4:00 pm Open Poster Viewing (Authors not required to be present) 8:00 pm–9:00 pm “C” posters 9:00 pm–10:00 pm “B” posters 10:00 pm–11:00 pm “A” posters

Saturday, April 2: 1:30 pm-2:30 pm Odd-Numbered Posters 2:30 pm-3:30 pm Even-Numbered Posters 7:00 pm–10:00 pm Open Poster Viewing (Authors not required to be present)

All posters must be removed from poster boards no later than 11:00 pm on Saturday, April 2. After that time, remaining posters will be removed by vendors and may be lost or thrown away. The GSA Administrative Office does not take responsibility for posters that are not removed by 11:00 pm on Saturday.

Registration, Book and T-Shirt Pickup – Atlas Ballroom Foyer Conference registration and book pickup will be open as follows: Wednesday, March 30 3:30 pm–9:00 pm Thursday, March 31 8:00 am–5:00 pm Friday, April 1 8:30 am–5:00 pm Saturday, April 2 8:30 am–4:00 pm

Note that attendees must be registered before attending the Opening General Session on Wednesday, March 30, 7:00 pm in order to attend that session.

Those who purchased t-shirts can pick them up at any time during normal registration hours but BEFORE noon on April 2. A limited number of additional t-shirts have been ordered and will be available for sale on-site.

General Information

Speaker Ready Room – Terrace Salon 3 All Speakers are required to load and check their presentation at least four hours (preferably the day before) in advance of the start of the session (not your specific time slot but the overall session time) in the Speaker Ready Room. Here is a schedule of the times that the Speaker Ready Room will be open:

Wednesday, March 30 3:00 pm-6:30 pm Thursday, March 31 7:00 am-3:00 pm Friday, April 1 7:00 am-3:00 pm Saturday, April 2 7:00 am-3:00 pm

IMPORTANT – Even if you have loaded your presentation before the conference you still must check in at the Speaker Ready Room. Presentations cannot be loaded in the meeting rooms.

Awards

Larry Sandler Memorial Lecture The Larry Sandler Memorial Lecture was established in 1988 by the colleagues, friends and students of Dr. Larry Sandler after his untimely death in February 1987. The award serves to honor Dr. Sandler for his many contributions to Drosophila genetics and his exceptional dedication to the training of Drosophila biologists. Any student completing his Ph.D. in an area of Drosophila research in the calendar year preceding the annual Drosophila Research Conference is eligible and may be nominated by his/her dissertation advisor. The Selection Committee for 2011 includes Chair, Claude Desplan, and committee members Allison Bardin, Richard Mann and Marek Mlodzik. The Committee reviews nominations, reads the dissertations of the finalists, and selects the awardee.

Past recipients of this honor are:

Bruce Edgar, 1988 Chaoyong Ma, 1996 Sean McGuire, 2004 Kate Harding, 1989 Abby Dernburg, 1997 Elissa Hallem, 2005 Michael Dickinson, 1990 Nir Hacohen, 1998 Daniel Ortiz-Barrientos, 2006 Maurice Kernan, 1991 Terence Murphy, 1999 Yu-Chiun Wang, 2007 Doug Kellogg, 1992 Bin Chen, 2000 Adam A. L. Friedman, 2008 David Schneider, 1993 James Wilhelm, 2001 Timothy Weil, 2009 Kendal Broadie, 1994 Matthew C. Gibson, 2002 Leonardo Barbosa Koerich, 2010 David Begun, 1995 Sinisa Urban, 2003

Poster Award Competition Posters are an important component of the Drosophila meeting and the Poster Award appropriately highlights the work that goes into a professional presentation of outstanding underlying science.

Nine awards will be given for the best poster designs. First ($500), second ($300) and third ($200) place prizes will be given to the undergraduate students, graduate students and postdocs judged to have the best posters. Both scientific merit and clarity of presentation will be evaluated. To be eligible, your poster must be displayed from 11:00 pm on March 30 through 10:00 pm on April 2, 2011. Additionally, your poster number, which will be preset, should not be moved or covered. Posters that are removed, not displayed or do not adhere to poster display guidelines will not be considered.

This competition is only open to students and postdocs. PIs are not eligible.

If you are a session chair you should submit your selections to Giovanni Bosco by 7:30 am on Friday, April 1 at [email protected].

Award Winners – Please bring and display your posters in the Atlas Ballroom Foyer on Sunday, April 3 by 7:00 am (boards will be available beginning at 10:00 pm on Saturday, April 2). Your award will be presented during the Sunday morning Plenary Session.

Awards

The DeLill Nasser Award for Professional Development in Genetics The DeLill Nasser Award for Professional Development in Genetics was established by the Genetics Society of America in mid-2001 in honor of the late DeLill Nasser, who served for 22 years as the program director of the Eukaryotic Genetics Section at the National Science Foundation.

The award fund, made possible by contributions from her family and friends, is growing steadily. It recognizes Dr. Nasser’s contributions to the field of genetics and her strong support of young scientists. Travel and tuition awards will be made annually to allow graduate students and postdoctoral trainees to attend meetings or enroll in laboratory courses.

Since 2002, deserving young investigators have been awarded to attend genetics research conference.

The 2011 awardees are:

Nicolas Buchon Mia T. Levine Ecole Polytechnique Federal Fred Hutchinson Cancer Res Ctr

Xu Chen Teresa R. O'Meara Univ of Wisconsin-Madison Duke Univ

Heather Flores Alexandra A. Soukup Cornell Univ Univ of Wisconsin-Madison

Daniel P. Kane Chaolong Wang Tufts Univ Univ of Michigan

Yunsik Kang Cornelia E. Zorca Univ of Wisconsin-Madison Yale Univ

The GSA strongly encourages all of its members and friends to donate. The current fund balance is over $48,000. Up to five percent of the fund amount will be awarded each year. Please make your check payable to Genetics Society of America and send it to Executive Director, GSA, 9650 Rockville Pike, Bethesda, MD 20814-3998. Please write “Nasser Fund” on the bottom left of the check.

Exhibits

As exhibitors at the 52nd Annual Drosophila Research Conference, the following companies have contributed to the support of this Conference. Registrants are encouraged to visit the exhibits in the Exhibition Hall and to take advantage of this opportunity to see the new products, publications and services available from these companies.

Actual Analytics Booth 212 Conviron Booth 216 7.11 Appleton Tower, 11 Crichton Street 590 Berry Street Edinburgh, EH8 9LE, UK Winnipeg, MB, Canada R3HOR9 Phone: 1-866-697-8154 (US), +44 7976 967531 (UK) Phone: 204/786-6451 E-mail:[email protected] Fax: 204/786-7736 URL: www.actualanalytics.com E-mail: [email protected] URL: www.conviron.com Actual FlyTrack is the world’s only commercially available video analysis system designed specifically for Conviron is a global supplier of controlled environment Drosophila research. The easy to use software accurately systems with primary application in Agricultural analyzes the movement of larvae and individual or pairs Biotechnology research. Our extensive product portfolio of drosophila from video. The detailed output includes includes single and multi-tier chambers and rooms, and locomotor statistics and automatically calculated CI in research greenhouses. Services encompass the entire CSV/Excel format. project life-cycle from early-stage design through to installation, project commissioning and on-going Azer Scientific Inc. Booth 115 maintenance and support. 189 Twin County Road Morgantown, PA 19543 Drosophila Genomics Research Phone: 610/524-5810 Center (DGRC) Booth 308 Fax: 610/901-3046 Indiana University E-mail: [email protected] 1001 E 3rd Street URL: www.AzerSci.com Jordan Hall 044 Bloomington, IN 47404 Azer Scientific offers a complete line of drosophila Fax: 812/856-9340 products. We have new FlyLock™ plugs in addition to E-mail: [email protected] our popular bottles and vials, making Azer your one URL: dgrc.cgb.indiana.edu source for all drosophila needs. We are constantly improving our product line, and welcome suggestions for The Drosophila Genomics Resources Center new product ideas! Call for your free samples. (dgrc.cgb.indiana.edu) serves the Drosophila community by collecting and distributing clones and cell lines of general interest and by assisting the community in using these materials. Visit our booth for information about upcoming services or to speak to DGRC personnel about our materials.

Exhibits

Genesee Scientific Booths 215, 314, NightSea Booth 316 8430 Juniper Creek Lane 213, 312 34 Dunelm Road San Diego, CA 92126 Bedford, MA 1730 Phone: 858/357-2017 Phone: 781/791-9508 Fax: 858/357-2070 Fax: 781/791-9519 E-mail: [email protected] E-mail: [email protected] URL: www.geneseesci.com URL: www.nightsea.com

Don’t miss new additions to Genesee’s comprehensive NightSea develops and manufactures lights and filters for “Flystuff™” catalog (available worldwide) featuring viewing and photographing fluorescence in the Genesee’s Fly Vial Reload System which racks vials in laboratory. Our equipment is used worldwide for seconds. Our Reload System is the environmentally identifying, sorting, and imaging organisms tagged with responsible and cost effective alternative to pre-racked fluorescent proteins and other fluorophores. At this show vials! Also see Genesee’s advancements in Drosophila we are introducing a new light and filter configuration for Anesthesiology! We offer interactive demonstrations and use with dissecting microscopes. expert consultation. Parter Medical Products Booth 107 Genetic Services Inc. Booth 113 17015 Kingsview Ave. One Kendall Square, Bldg. 300 Carson, CA 90746 Cambridge, MA 02139 Phone: 610/972-5901 Phone: 617/872-3135 Fax: 310/327-8601 Fax: 617/252-9119 E-mail: [email protected] E-mail: [email protected] URL: www.partermedical.com URL: www.geneticservices.com Parter Medical is the leading manufacturer of high quality Genetic Services Inc. offers a variety of services for the plasticware for Drosophila research. Our Drosophila and Model Organism Research Community disposable/reusable vials and bottles are made in a wide including, P-element and site directed injections and selection of sizes, materials, and packaging choices. All transgenic production, balancing, genetic screening, ZFN of our products are manufactured for optimum durability injections, mosquito injections, stock maintenance and and offer excellent value. Stop by and see why our fresh more. Let us help speed up your research and make your ideas lead to great Drosophila products. lab more competitive! Percival Scientific, Inc. Booth 208 Genewiz, Inc. Booth 209 505 Research Drive 115 Corporate Blvd. Perry, IA 50220 South Plainfield, NJ 07080 Phone: 800/695-2743 Phone: 877/436-3949 Fax: 515/465-9464 Fax: 908/333-4511 E-mail: [email protected] E-mail: [email protected] URL: www.percival-scientific.com URL: www.genewiz.com Percival Scientific's cutting edge technology is at the core GENEWIZ, Inc. provides award-winning DNA of our commitment to delivering the best products on the sequencing, molecular biology, and genomic services. market today. This commitment is clear with the Percival Build codon-optimized transgenes through our powerful DR-36 and DR-41 Series which are dedicated to offer the Gene Synthesis technologies, and get high-quality best features for Drosophila research. plasmids from mini-to-giga scales using our Plasmid Preparation services. With >10 years experience in DNA sequencing, we are well-equipped to handle sequencing projects of all complexities.

Exhibits

Powers Scientific, Inc. Booth 214 University of Maryland Insect Booth 306 PO Box 268 Transformation Facility Pipersville, PA 18947 9600 Gudelsky Dr Phone: 215/230-7100 Rockville, MD 20850 Fax: 215/230-7200 Phone: 240/314-6331 E-mail: [email protected] Fax: 240/314-6255 URL: www.powersscientific.com E-mail: [email protected] URL: http://ibbr.umd.edu/insect_transformation Powers Scientific, Inc. - offering Drosophila growth chambers with coated coils in 5 sizes (from 6-55 c.f. The University of Maryland's Insect Transformation capacity) with four levels of temperature, humidity and Facility specializes in transforming non-model insects. lighting control to fit the application and price range. Services include "fee for service" transformation (with Mosquito, Sand Fly and c. Elegans growth chambers also established protocols), collaboration (to develop new available. protocols), training (microinjection, insect rearing) and consultation. The Facility has a staff with broad and deep Sable Systems International Booth 109 experience in insect biology and transformation 6000 S. Eastern Ave. Bldg 1 technologies. Las Vegas, NV 89119 Phone: 702/269-4445 Vienna Drosophila RNAi Center Booth 207 Fax: 702/269-4446 Dr. Bohr - Gasse 3-5 E-mail: [email protected] 1030 Vienna, Austria URL: www.sablesys.com Phone: 43 1790444500 Fax: 43 17904422 4546 Sable Systems International is the widely cited, E-mail: [email protected] international standard in high resolution metabolic URL: www.vdrc.at screening and calorimetry. Our systems can measure Drosophila gas exchange in real time. Technical support VDRC has generated, maintains and distributes two is by published experts in insect respirometry. Please drop independent Drosophila RNAi transgenetic libraries. The by our booth and discuss what we can do for your GD collection, constructed by random P-element research. transgenesis and new KK library, constructed by phiC31 mediated transgenesis into the VIE-260b site. The KK Union Biometrica, Inc. Booth 117 and GD RNAi lines target distinct gene regions. RNAi 84 October Hill Road lines are available to all researchers at http://www.vdrc.at Holliston, MA 01746 Phone: 508/893-3115 Fax: 508/893-8044 E-mail: [email protected] URL: www.unionbio.com

Union Biometrica Large Particle Flow Cytometers automate the analysis, sorting & dispensing of objects too big/fragile for traditional cytometers, e.g., small model organisms like Drosophila, large cells / cell clusters, and beads. COPAS or new BioSorter with interchangeable modules to cover the full 10-1500m range – ideal for shared instrument grants.

OPENING/PLENARY SESSIONS

Wednesday, March 30 7:00 PM–9:15 PM Thursday, March 31 8:30 AM–12:00 PM Atlas Ballroom Atlas Ballroom

Opening General Session Plenary Session I

Room: Atlas Ballroom Moderator: Daniel Barbash, Cornell University, Ithaca, NY Presentations: Room: Atlas Ballroom 7:00 pm Welcome and Opening Remarks. Giovanni Bosco. University of Arizona, Tucson. Presentations:

7:10 pm GSA Update. Genetics Society of America 8:30 am Image Award Presentation. Michelle (GSA), Bethesda, MD Arbeitman. University of Southern California, Los Angeles. 7:15 pm Larry Sandler Award Presentation. Allison Bardin. Curie Institute, Paris, France. 8:35 am Ageing Flies. Linda Partridge. Gen, Evolution & Environmt, University College London, United 7:20 pm Larry Sandler Lecture. Kingdom.

8:05 pm Historical Lecture Introduction. Leslie 9:00 am From the Cambrian to the Sushi Bar: Griffith. Brandeis University, Waltham, MA TRPA1 and the Evolution of Thermal and Chemical Sensing. Paul A. Garrity. National Center for Behavioral 8:10 pm Historical Lecture. Featuring featuring Genomics, Brandeis Univ, Waltham, MA. Stephen Goodwin, Ulrike Heberlein, Michael Rosbash and Scott Waddell . Michael Rosbash. Moderator, 9:30 am Pleiotropy, Environment, and Non- Brandeis University, Waltham, MA Immunological Determinants of Defense Against Infection in Drosophila. Brian P. Lazzaro. Cornell 9:10 pm GSA Award Presentation - Congratulations University, Ithaca, NY. to John Carlson. R. Scott Hawley. Stowers Institute for Medical Research, Kansas City, MO 10:00 am Break

10:30 am Genetic Analysis of Vesicle Movement. Lawrence S. B. Goldstein. University of California, San Diego.

11:00 am Contrasting Patterns of Polymorphism and Divergence in the Evolution of Gene Expression. Patricia J. Wittkopp. University of Michigan, Ann Arbor.

11:30 am Chromosomal Organization of Drosophila melanogaster Genome. Igor F. Zhimulev. Inst Chemical Biology & Fundamental Medicine, Novosibirsk, Russian Federation; Department of Molecular and Cellular Biology.

OPENING/PLENARY SESSIONS

Sunday, April 3 8:30 AM–12:00 NOON Notes Atlas Ballroom

Plenary Session II

Moderator: Giovanni Bosco, University of Arizona, Tucson

Room: Atlas Ballroom

Presentations:

8:30 am Poster Award Presentation. Giovanni Bosco. University of Arizona, Tucson.

8:35 am Nucleosome Dynamics and Gene Regulation. Kami Ahmad. Harvard Medical School, Boston, MA

9:00 am The Secret Lives of Flies: What Nature Means for the Laboratory. Therese A. Markow. University of California San Diego.

9:30 am Autoregulatory and Paracrine Control of Synaptic and Behavioral Plasticity by Octopaminergic Signaling. Vivian Budnik. Neurobiology, University of Massachusetts Medical School, Worcester.

10:00 am - Break

10:30 am Biogenesis and Function of microRNAs. Eric C. Lai. Sloan Kettering Institute, NY.

11:00 am Understanding the 'Why?': Evolution of Behavior in Social Insects. Anna Dornhaus. University of Arizona, Tucson.

11:30 am The Mechanics of Shape Change in the Drosophila Embryo. Eric F. Wieschaus. HHMI; Lewis- Sigler Institute for Integrative Genomic, Princeton University, NJ.

Workshops

Wednesday, March 30 12:00 PM–6:00 PM Friday, April 1 1:45 PM–3:45 PM

Ecdysone Workshop Cell Competition

Room: Pacific Salon 2/3 Room: Pacific Ballroom Salon 2 Organizers: Christen Mirth, Instituto Gulbenkian de Organizers: Wu-Min Deng, Florida State University, and Ciencia, and Tatsushi Igaki, Kobe Univeristy, and Arash Bashirullah, University of Wisconsin Eduardo Moreno, CNIO.

The Ecdysone Workshop welcomes all those interested in During their lifetime, cells of multicellular animals can how hormones regulate development, behavior and life suffer insults (mutations, transient errors, infections, history. We will discuss mechanisms of 20- oxidative damage) that may compromise their fitness. In hydroxyecdysone, juvenile hormone, and peptide Drosophila the process of "cell competition" that seems to hormone signaling in Drosophila and other insect species. recognize and eliminate less adapted or weaker cells of Platform talks of approximately 15 minutes will be developmental primordia, ensuring that viable but grouped into sessions according to topic. Topics for suboptimal cells do not accumulate during development presentation include (but will not be limited to): hormones or ageing. How groups of cells compare their relative and evolution, hormone synthesis and secretion, fitness levels and decide which cell will remain in the endocrine control of development, and the effects of tissue ("winner cell") and which cell will be eliminated hormones on growth and metabolism. Programs will be ("loser cell") will be the main topic of the workshop. available upon request by email ([email protected] or [email protected]). Speakers:

Speakers: Nick Baker, Albert Einstein College of Medicine Erika Bach, New York University School of Medicine Fred Nijhout, Duke University Wu-Min Deng, Florida State University Kim Rewitz, Roskilde University Tatsushi Igaki, Kobe University Randy Hewes, University of Oklahoma Laura Johnston, Columbia University Alexander Shingleton, Michigan State University Eugenia Piddini, University of Cambridge Eduado Morena, University of Bern

Workshops

Friday, April 1 1:45 PM–3:45 PM Friday, April 1 1:45 PM–3:45 PM

Apoptosis, Autophagy and Other Cell Death Chemical Genetics and Drug Screening Mechanisms Room: Pacific Ballroom Salon 7 Room: Pacific Ballroom Salon 3 Organizers: Tin Tin Su, University of Colorado, and Organizers: Andreas Bergman, MD Anderson Cancer Claudio Sunkel, IBMC Center, and Eli Arama, Weizmann Institute We will cover the use of small molecules in combination with genetic manipulation to study biological phenomena. This workshop is a forum for the discussion of cell death One goal of these studies would be to leverage the results mechanisms in Drosophila. Apoptosis is the most widely in designing screens for potential therapeutics for human recognized form of cell death in development. However, diseases. there is increasing awareness that alternative cell death mechanisms exist. Autophagy has emerged as an important pathway for cell death during metamorphosis. Friday, April 1 1:45 PM–3:45 PM Other non-apoptotic forms of cell death (Entosis, Necrosis) have also been described. The workshop is Mechanisms and Functions of Chromosome Pairing intended to highlight recent advances in cell death research and to foster communication and collaboration Room: Pacific Ballroom Salons 4-5 between individuals working in the field. Topics will Organizers: Jeff Sekelsky, University of North Carolina, include all aspects of cell death regulation for Drosophila and biology. Giovanni Bosco, University of Arizona

Speakers: Studies with Drosophila have led to numerous Offer Gerlitz, The Hebrew University-Hadassah Medical fundamental contributions to our understandings of School chromosome structure, behavior, and function. Current Donald G. McEwen, University of Texas Health Science studies by a number of laboratories are now unraveling Center at San Antonio one of the most mysterious aspects of chromosome Eric H. Baehrecke, University of Massachusetts Medical behavior: pairing. At this workshop we will discuss School approaches to understanding mechanisms by which Anat Florentin, Weizman Institute of Science chromosomes and homologous sequences find one Allison K. Timmons, Boston University another, new insights into functions of pairing, and Can Zhang, University of Florida studies of the consequences of failure to pair. Pierre Dourlen, CNRS/Ecole Superieure de Lyon Hyung Don Ryoo, New York University School of Speakers: Medicine Kim McKim, Rutgers University Sharon Bickel, Dartmouth College Bruce McKee, University of Tennessee Eric Joyce, Harvard University Giovanni Bosco, University of Arizona Jim Birchler, University of Missouri Bill Gelbart, Harvard University Frederic Bantignies, Institute de Genetique Humaine

Workshops

Saturday, April 2 6:45 PM–8:45 PM Saturday, April 2 6:45 PM–8:45 PM

Confocal Imaging Quantitative Biology of Cell Signaling and Pattern Formation Room: Pacific Ballroom Salon 2 Organizer: Steve Paddock, HHMI/University of Room: Pacific Ballroom Salons 4-5 Wisconsin Organizers: David Arnosti, Michigan State University, and Confocal microscopy is an established technique with Stas Shvartsman, Princeton University, and applications for the imaging of many different stages of Thomas M Onorato, Laguardia Community the Drosophila life cycle. The laser scanning confocal College/CUNY. microscope continues to be the instrument of choice for most routine work. Applications include the imaging of This workshop will highlight for the biology community the spatial distribution of macromolecules in either fixed recent advances in quantitative modeling of or living specimens, the automated collection of 3D data, developmental processes. We will feature scientists the imaging of multiple labeled specimens and the whose work focuses on formulation and experimental measurement of physiological events in living cells. validation of quantitative models of signal transduction Significant improvements have been made at all stages of and gene expression networks. Topics will include the imaging process, and also in the analysis, display, modeling approaches that range from thermodynamic reproduction, sharing and management of confocal data representations of transcriptional elements to large-scale using bioinformatics techniques. differential equation models on the scale of the organism. Presentations will be geared to demonstrating the potential and limitations of modeling for the biologist Saturday, April 2 6:45 PM–8:45 PM contemplating the application of quantitative methods to their data sets and systems. Drosophila Research and Pedagogy at Primarily Undergraduate Institutions (PUI)

Room: Pacific Ballroom Salon 1 Organizers: Jason Duncan, Willamette University, and Janet Rollins, College of Mount Saint Vincent

This workshop focuses on increasing the quality and visibility of Drosophila research performed at primarily undergraduate institutions (PUIs) and facilitating faculty and students in these endeavors. The goals include: 1) encouraging undergraduate research by providing a forum for students to make oral presentations; 2) connecting people interested in this career path with current PUI faculty; 3) establishing a network among current PUI faculty to promote discussion and provide support on professional issues that differ from those at large institutions; 4) sharing concepts and techniques that encourage the integration of Drosophila as a teaching tool in the classroom and laboratory.

Workshops

Saturday, April 2 6:45 PM–8:45 PM Saturday, April 2 6:45 PM–8:45 PM

Emerging Model Arthropods Everything You Ever Wanted to Know About Sex

Room: Pacific Ballroom Salon 3 Room: Pacific Ballroom Salons 6-7 Organizer: Molly Duman-Scheel, Indiana University Organizer: Mark Van Doren, Johns Hopkins University School of Medicine The workshop will cover the molecular genetics, The recent development of new arthropod research development, neurobiology, genomics, evolution, and models is refining our understanding of established population genetics of sexual dimorphism, with an models such as Drosophila melanogaster, initiating new emphasis on cross-disciplinary interactions. Presentations avenues of research, promoting comparative studies, and by invited speakers and selected abstracts from each providing insight into the phylogenetic context in which discipline will be followed by moderated discussions. The fruit flies have evolved. This workshop will provide a speakers are encouraged to summarize the key ideas forum for investigators who are developing new model behind their research for people working in other fields, arthropod systems, including Chironomus riparius, outline the main unsolved questions, offer their opinions Episyrphus balteatus, Acyrthosiphon pisum, Tribolium about future directions, and suggest connections that castaneum, Aedes aegypti, and Parhyale hawaiensis, to could be built with other disciplines. disseminate their work to and get feedback from the Drosophila community. Such interaction will promote development of resources and tools for studying emerging Saturday, April 2 9:00 PM–11:00 PM model arthropods and facilitate comparative research studies. modENCODE Workshop

Speakers: Room: Atlas Ballroom

Organizers: Susan Celniker, Lawrence Berkeley Sue Brown, Kansas State University National Laboratory, and Greg Davis, Bryn Mawr College Gary Karpen, Lawrence Berkely National Molly Duman-Scheel, Indiana University School of Laboratory Medicine, University of Notre Dame Nipam H. Patel, University of California Urs Schmidt-Ott, University of Chicago The modENCODE workshop will update the community on the model organism ENCODE project that endeavors to identify all sequence-based functional elements in the D. melanogaster genome. The project is organized and conducted by a research network called the modENCODE Consortium. Topics include the transcriptome, regulatory elements, chromosomal proteins, small and microRNAs and origins of replication and data coordination

CONCURRENT PLATFORM SESSIONS THURSDAY, MARCH 31 4:30 pm – 6:30 pm Program number is in bold above title. The first author is the presenter. Full abstracts can be found online

Cell Division and Growth Control RNA Biology

Moderators: Iswar Hariharan, University of California, Berkeley and Moderators: William Theurkauf, University of Massachusetts Medical Nicholas Baker, Albert Einstein College of Medicine, Bronx, NY School, Worcester and Elizabeth Gavis, Princeton University, Princeton, Room: Town & Country New Jersey Room: Golden West 1 - 4:30 Control of the mitotic cleavage plane by local tissue topology. William 9 - 4:30 T. Gibson1,2,4,5, James H. Veldhuis3, Boris Y. Rubinstein2, Heather N. The Yb Body, a Major Site for piRNA Biogenesis and a Gateway for Cartwright2, Norbert Perrimon4, G. Wayne Brodland3, Radhika Piwi Expression and Transport to the Nucleus in Somatic Cells. Nagpal5, Matthew C. Gibson2,6. 1) Program in Biophysics, Harvard Hongying Qi, Toshiaki Watanabe, Hsueh-Yen Ku, Na Liu, Mei University, Cambridge, MA 02138, USA; 2) Stowers Institute for Zhong, Haifan Lin. Department of Cell Biology, Yale Stem Cell Medical Research, Kansas City, MO 64110, USA; 3) Department of Center, New Haven, CT. Civil and Environmental Engineering, University of Waterloo, Waterloo, ON N2L 3G1, Canada; 4) Department of Genetics, Howard 10 - 4:45 Hughes Medical Institute, Harvard Medical School, Boston, MA 02115, Complex evolutionary changes in germline transposon silencing USA; 5) School of Engineering & Applied Sciences, Harvard revealed by Drosophila interspecific hybrids. Erin S. Kelleher, Daniel University, Cambridge, MA 02138, USA; 6) Department of Anatomy A. Barbash. Dept Molec Biol & Gen, Cornell Univ, Ithaca, NY. and Cell Biology, Kansas University Medical Center, Kansas City 64110, KS. 11 - 5:00 piRNA-mediated adaptation to transposon invasion in Drosophila. 2 - 4:45 Jaspreet S. Khurana1, Jie Wang2, Anetta Nowosielska1, Jia Xu2, Artificial cleavage furrows and RhoGEF at the midblastula transition. Zhiping Wemg2, William Theurkauf1. 1) Program in Molec Med, Justin M. Crest, Kirsten Concha-Moore, William Sullivan. Dept Univ Massachusetts Med Sch, Worcester, MA; 2) Program in MCD Biol, Univ California, Santa Cruz, CA. Bioinformatics and Integrative Biology, Univ Massachusetts Med Sch, Worcester, MA. 3 - 5:00 The Conserved Transcription Factor DREF Regulates Ribosome 12 - 5:15 Synthesis and Growth Downstream of the Insulin/TOR Pathway. Deficiency of the single Drosophila let-7 microRNA results in cardiac Lauren E. Killip, Savraj Grewal. Department of Biochemistry and dilation and arrhythmias. Jerome Cartry, Nikki Alayari, Timothy Molecular Biology, University of Calgary, Calgary, Alberta, Canada. Iafe, Karen Ocorr, Rolf Bodmer. Development and Aging Program, NASCR Center, Sanford-Burnham Medical Research Institute, La Jolla, 4 - 5:15 CA, USA. Wbp2, a novel regulator of the Hippo organ size-control pathway. Kieran F. Harvey1, Xiaomeng Zhang1, Claire C. Milton1, Carole L. 13 - 5:30 C. Poon1, Wanjin Hong2. 1) Cancer Cell Biology, Peter MacCallum miRNA-mediated feedback inhibition of JAK/STAT morphogen Cancer Ctre, Melbourne, VIC, Australia; 2) Institute of Molecular and signaling establishes a cell fate threshold. Wan H. Yoon, Denise J. Cell Biology, Singapore. Montell. Department of Biological Chemistry Center for Cell Dynamics Johns Hopkins University School of Medicine 855 North Wolfe St., 5 - 5:30 Suite 450 Baltimore, MD 21205, USA. Genetic study for non-cell autonomous tumor growth regulation. Shizue Ohsawa, Yoshitaka Sato, Mai Nakamura, Aya Nagao, Masato 14 - 5:45 Enomoto, Tatsushi Igaki. Dept Cell Biol, G-COE, Kobe Univ, Kobe, The Drosophila pan gu kinase complex regulates RNP stability via Japan. ubiquitin-dependent proteolysis. James E. Wilhelm, Brian Sato, Risa Broyer. Cell and Developmental Biology, UC San Diego, La Jolla, CA. 6 - 5:45 Dynamics and Biomechanics of Histoblast Expansion. Sofia Menezes- 15 - 6:00 Cabral1,2, Carla Prat-Rojo1, Philippe-Alexandre Pouille1, Javier Lost and Rump interact to mediate a late phase of germ plasm Buceta3, Enrique Martín-Blanco1. 1) IBMB-CSIC, PCB, Barcelona, accumulation during Drosophila oogenesis. Kristina S. Sinsimer, Spain; 2) Doctoral Programme in Biomedicine and Experimental Roshan A. Jain, Jack J. Lee, Elizabeth R. Gavis. Molec Biol, Biology (PDBEB), CNC, Universidade Coimbra, Coimbra, Portugal; 3) Princeton Univ, Princeton, NJ. Co.S.Mo. Lab, PCB, Barcelona, Spain. 16 - 6:15 7 - 6:00 Drosophila HPat interacts with the fragile X mental retardation protein Tao-1 sterile-20 kinase activates Salvador-Warts-Hippo signaling. Pam and the miRNA pathway to regulate synaptic structure. Sarala J. J. Vanderzalm, Julian Boggiano, Richard Fehon. Molecular Genetics Pradhan1, Leslie M. Rozeboom1, Ravjot Dhatt1, Mani Ramaswami2, & Cell Biology, University of Chicago, Chicago, IL. Scott A. Barbee1. 1) Department of Biological Sciences and Eleanor Roosevelt Institute, University of Denver, Denver, CO 80208, USA; 2) 8 - 6:15 Smurfit Institute of Genetics and TCIN, Lloyd Building, Trinity College A Screen for Conditional Tumor Suppressor Genes identifies Myopic as Dublin, Dublin-2, Ireland. an Endosomal regulator of Yorkie nuclear signal outputs. Melissa 1 2 2 1 Gilbert , Marla Tipping , Alexey Veraksa , Kenneth H. Moberg . 1) Department of Cell Biology, Emory University School of Medicine, Atlanta, GA; 2) Department of Biology, University of Massachusetts, Boston MA.

CONCURRENT PLATFORM SESSIONS THURSDAY, MARCH 31 4:30 pm – 6:30 pm Program number is in bold above title. The first author is the presenter. Full abstracts can be found online

Neurogenetics and Neural Notes Development

Moderators: Tom Jongens, University of Pennsylvania, Philadelphia and Daniela C Zarnescu, University of Arizona, Tucson Room: California

17 - 4:30 A neurogenic placode allocates neural versus neuroendocrine lineages by Notch and Egfr signaling. Helen J. Hwang, Eric Rulifson. Univ California, San Francisco.

18 - 4:45 The bHLH Repressor Deadpan is Differentially Required for Maintaining the Self-renewal of Two Distinct Types of Neural Stem Cells in Drosophila. Sijun Zhu1, Jill Wildonger1, Suzanne Barshow1, Susan Younger1, Yaling Huang2, Tzumin Lee2, Lily Jan1, Yuh Nung Jan1. 1) Dept of Physiology, Howard Hughes Medical Institute, University of California San Francisco, San Francisco, CA; 2) Janelia Farm Research Campus, Howard Hughes Medical Institute, Ashburn, VA.

19 - 5:00 Glial Control of Synapse Assembly at the Neuromuscular Junction. Kimberly S. Kerr, Yuly Fuentes-Medel, Marc Freeman, Vivian Budnik. Neurobiology, UMass Medical School, Worcester, MA.

20 - 5:15 Kismet regulates axon morphology, memory, and locomotion in a Drosophila model of CHARGE Syndrome. Daniel R. Marenda, David J. Melicharek, Laura C. Ramirez, Sukhdeep Singh, Rhea Thompson. Department of Biology, Drexel University, Philadelphia, PA.

21 - 5:30 Selective Disruption of Dscam1 Homophilic Interaction Reveals Its Essential Role in Neuronal Self-Avoidance. Wei Wu1, David Baker2, Larry Zipursky1. 1) Department of Biological Chemistry, HHMI/UCLA, Los Angeles, CA; 2) Department of Biochemistry, HHMI/University of Washington, Seattle, WA.

22 - 5:45 Kataninp60-Like1 regulates dendritic outgrowth of Drosophila larval class IV sensory neurons and the nocifensive response by promoting microtubule growth. Andrea Stewart1, Dan Tracey2, Nina Tang Sherwood1. 1) Biology, Duke Univ, Durham, NC; 2) Anesthesiology, Cell Biology and Neurobiology, Duke Univ, Durham, NC.

23 - 6:00 dEHBP1 regulates endocytosis and active zone assembly at the developing neuromuscular junction. Nikos Giagtzoglou1, Yong Qi Lin1, Claire Haueter1, Hugo Bellen1,2,3,4. 1) Howard Hughes Medical Institute, Baylor College of Medicine, Houston, TX. 77030; 2) Program in Developmental Biology, Baylor College of Medicine, Houston, TX. 77030; 3) Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, TX. 77030; 4) Department of Neuroscience, Baylor College of Medicine, Houston, TX. 77030.

24 - 6:15 Rotund regulates odorant receptor choice by specifying sensillar subtypes. Qingyun Li1, Tal Soo Ha3, Dean P. Smith3, Pelin C. Volkan1,2. 1) Biology, Duke University, Durham, NC; 2) Duke Institute for Brain Sciences, Durham , NC; 3) Department of Pharmacology and Center for Basic Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas.

CONCURRENT PLATFORM SESSIONS FRIDAY, APRIL 1 8:30 am – 10:15 am Program number is in bold above title. The first author is the presenter. Full abstracts can be found online

Evolution and Quantitative Drosophila Models of Human Genetics Disease

Moderators: Yun Tao, Emory University, Atlanta, Georgia and Todd Moderators: Ethan Bier, University of California, San Diego and Schlenke, Emory University, Atlanta, Georgia Hannele Ruohola-Baker, University of Washington, Seattle Room: Town & Country Room: Golden West

25 - 8:30 39 - 8:30 The Drosophila Genetic Reference Panel: A whole genome association Identifying Small Molecules as Combination Therapy for Cancer. Mara resource for quantitative traits. Stephen Richards1, Dianhui Zhu1, Yi N. Stewart, Petros Yoon, Tin Tin Su. Molecular,Cellular & Dev Biol, Han1, Julien Ayroles2, Mary Anna Carbone2, Eric Stone2, Trudy Univ Colorado,Boulder, Boulder, CO. Mackay2, Richard Gibbs1. 1) Molecular Human Genetics, Baylor Col Medicine, Houston, TX; 2) Department of Genetics, North Carolina 40 - 8:45 State University, Raleigh, NC. Genetic and pharmacological approaches that overcome immune suppression caused by elevated CO2 (hypercapnia) in Drosophila and 26 - 8:45 mammals. Greg J. Beitel1, I. Taneli Helenius1,2, Thomas Krupinski1, Widespread multi-nucleotide mutation events in Drosophila Humberto Trejo2, Khalilah L. Gates2, Peter H. S. Sporn2, Jacob I. melanogaster and other organisms. Daniel R. Schrider1,2, Jonathan N. Sznajder2. 1) Dept. of Molecular Biosciences, Northwestern University, Hourmozdi1,2, Matthew W. Hahn1,2. 1) Department of Biology, Evanston, IL; 2) Dept. of Medicine, Div. of Pulmonary and Critical Indiana University, Bloomington, IN; 2) School of Informatics and Care, Northwestern University, Chicago, IL. Computing, Indiana University, Bloomington, IN. 41 - 9:00 27 - 9:00 Epigenetic regulation of learning and memory by Drosophila Phenotypic McDonald-Kreitman tests of mitochondrial genotypes EHMT/G9a. Jamie M. Kramer1, Korinna Kochinke1, Merel A. W. reveals neutral divergence and non-neutral polymorphism of life history Oortveld1, Hendrik Marks2, Daniela Kramer1, Eiko K. de Jong1, traits. David M. Rand, Nicolas Jourjine, Stephanie Le, Marissa Zoltan Asztalos3, J. Timothy Westwood4, Hendrik G. Stunnenberg2, Holmbeck, Colin Meiklejohn, Kristi Montooth. Ecology & Marla B. Sokolowski4, Krystyna Keleman5, Huiqing Zhou1, Hans Evolutionary Biol, Brown Univ, Providence, RI. van Bokhoven1, Annette Schenck1. 1) Department of Human Genetics, Radboud University Nijmegen Medical Centre, The Netherlands; 2) 28 - 9:15 Department of Molecular Biology, Nijmegen Centre for Molecular Life Ultra-fine scale recombination heterogeneity in D. melanogaster. Nadia Sciences, The Netherlands; 3) Aktogen Ltd., Department of Genetics, Singh1, Eric Stone1, Charles Aquadro2, Andrew Clark2. 1) Genetics, University of Cambridge, Cambridge, UK; 4) Department of Biology, North Carolina State University, Raleigh, NC; 2) Molecular Biology and University of Toronto, Canada; 5) Institute of Molecular Pathology, Genetics, Cornell University, Ithaca, NY. Vienna, Austria.

29 - 9:30 42 - 9:15 Intraspecific variation in recombination rates in Drosophila Altered signaling at the muscle synapse causes temperature-sensitive melanogaster based on ultra-dense whole-genome genetic maps. Josep seizures in Drosophila dystrophic muscles. April K. Marrone1, Mariya M. Comeron1,2, Ramesh Ratnappan1, Samuel S. Bailin1. 1) M. Kucherenko1, Robert Wiek2, Martin Goepfert2, Halyna R. Department of Biology, University of Iowa, Iowa City, IA; 2) Roy J. Shcherbata1. 1) Max Planck Institute for biophysical chemistry Am Carver Center for Genomics, University of Iowa. Fassberg 11, 37077, Goettingen, Germany; 2) Department of Cellular Neurobiology, Georg August University, Max Planck Institute for 30 - 9:45 experimental medicine, Hermann Rein 3, 37075 Goettingen, Germany. Genetic asymmetry at the Dobzhansky-Muller gene Lhr is the result of cis-by-trans regulatory divergence of an ancestral hybrid lethal function. 43 - 9:30 Shamoni Maheshwari, Daniel Barbash. Dept Molec Biol & Gen, Living without telomeres: complete suppression of tefu/atm Cornell Univ, Ithaca, NY. developmental phenotype. Sarah R. Oikemus1, Uma Chalasani1, Sze Ham Chan2, Amy Marie Yu2, Mitch McVey2, Michael Brodsky1. 1) 31 - 10:00 Dept PGF&E, Univ Massachusetts, Worcester, Worcester, MA; 2) Dept Many small-effect mutations in a transcriptional enhancer caused Genetics, Tufts School of Biomedical Sciences, Boston, MA. evolution of Drosophila larval morphology. Nicolas Frankel1,4, Deniz F. Erezyilmaz1,4, Alistair P. McGregor2, Shu Wang1, François 44 - 9:45 Payre3, David L. Stern1. 1) Howard Hughes Medical Institute and Manipulating the Kinome in Drosophila Glia to Model Human Glioma. Department of Ecology and Evolutionary Biology, Princeton University, Renee D. Read1, Tim Fenton2, Frank B. Furnari2, Webster K. Princeton, NJ 08544, USA; 2) Institut für Populationsgenetik, Cavenee2, John B. Thomas1. 1) Molecular Neurobiology Laboratory, Veterinärmedizinische Universität Wien, A-1210 Vienna, Austria; 3) Salk Institute for Biological Studies, La Jolla, CA; 2) Ludwig Institute Université de Toulouse and Centre National de la Recherche for Cancer Research, University of California at San Diego, 9500 Scientifique, Centre de Biologie du Développement, UMR5547, Gilman Drive, La Jolla, CA. Toulouse, F-31062, France; 4) equal contribution. 45 - 10:00 Dysregulated intracellular pH and dysplasia. Bree Grillo-Hill, Maite Jimenez-Vidal, Diane Barber. Dept. of Cell and Tissue Biology, UC San Francisco, San Francisco, CA.

CONCURRENT PLATFORM SESSIONS FRIDAY, APRIL 1 8:30 am – 10:15 am Program number is in bold above title. The first author is the presenter. Full abstracts can be found online

Pattern Formation Notes

Moderators: Angela Stathopoulos, California Institute of Technology, Pasadena and David M Umulis, Purdue University, West Lafayette, Indiana Room: California

53 - 8:30 Live analysis of the Dorsal nuclear gradient. Gregory T. Reeves1, Angelike Stathopoulos2. 1) Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, NC; 2) Division of Biology, California Institute of Technology, Pasadena, CA.

54 - 8:45 Deubiquitinases and ubiquitin ligases fine-tune interpretation of the Dpp and Dorsal morphogen gradients. Stuart J. Newfeld, Michael Stinchfield, Ashley Castillo, Estela Arcineiga, Norma Takaesu. Sch Life Sci, Arizona State Univ, Tempe, AZ.

55 - 9:00 Positioning of Bicoid target gene expression boundaries by combinatorial repression mechanisms. Hongtao Chen, Zhe Xu, Jerry Huang, Stephen Small. New York University, New York, NY10003.

56 - 9:15 Spatial diversification of BMP signaling by a patterned receptor across Drosophila species. Matthew G. Niepielko, Yainna Hernáiz- Hernándeza, Nir Yakoby. Biology Department and Center for Computational and Integrative Biology, Rutgers, The State University of New Jersey, Camden, NJ 08102.

57 - 9:30 Wnt signal plays an essential role in the left-right asymmetric development of the embryonic gut in Drosophila. Junpei Kuroda1, Reo Maeda1, Yasuhiro Kawakatsu1, Mitsutoshi Nakamura1, Naotaka Nakazawa1, Ayumi Ozaki1, Akira Ishio1, Ryo Hatori1, Shigenori Nonaka2, Kenji Matsuno1. 1) Department of Biological Science and Technology, Tokyo University of Science, Noda, Japan; 2) National Institute for Basic Biology, Okazaki, Japan.

58 - 9:45 hedgehog activation of Notch drives proliferation at the AP organizer of the Drosophila wing imaginal disc. David J. Casso1, Brian Biehs2, Thomas Kornberg2. 1) Dept Biochem/Biophysics, Univ California, San Francisco, San Francisco, CA; 2) Cardiovascular Research Institute University of California San Francisco, CA.

59 - 10:00 Scaling properties of Dpp signaling in the growing Drosophila wing imaginal disc. Fisun Hamaratoglu1, Aitana Morton de Lachapelle2, Georgios Pyrowolakis3, Sven Bergmann2, Markus Affolter1. 1) Growth and Development, Biozentrum, University of Basel, Basel, Switzerland; 2) Department of Medical Genetics, University of Lausanne & Swiss Institute of Bioinformatics, Lausanne, Switzerland; 3) Department of Developmental Biology, University of Freiburg, Freiburg, Germany.

CONCURRENT PLATFORM SESSIONS FRIDAY, APRIL 1 10:45 am – 12:30 pm Program number is in bold above title. The first author is the presenter. Full abstracts can be found online

Cell Cycle and Cell Death Evolution and Quantitative Genetics (continued)

Moderators: Helena Richardson, Peter MacCallum Cancer Institute, East Room: Town & Country Melbourne, Australia and Tin Tin Su, MCD Biology, Boulder, Colorado Room: California 32 - 10:45 The genetic basis of rapidly evolving male genital morphology in 60 - 10:45 Drosophila. John P. Masly1,2, Justin E. Dalton2, Sudeep Srivastava2, Regulation of translesion DNA polymerases by the E3 ubiquitin ligase Liang Chen2, Michelle N. Arbeitman2. 1) Department of Zoology, NOPO during early embryogenesis. Julie A. Merkle, Laura A. Lee. University of Oklahoma, Norman, OK; 2) Division of Biological Cell and Developmental Biology, Vanderbilt University, Nashville, TN. Sciences, University of Southern California, Los Angeles, CA.

61 - 11:00 33 - 11:00 The translational regulator Caprin is specifically phosphorylated at the Retrogenes Out of the Z Chromosome in Silkworm. Maria mid-blastula transition. Ophelia Papoulas. Sect MCD Biol, Univ Texas, Vibranovski, Jun Wang, Manyuan Long. Ecology & Evolution, Univ Austin, TX. Chicago, Chicago, IL.

62 - 11:15 34 - 11:15 Role of RNA polymerase II in controlling the number of nuclear Selection pressures on sex-biased genes depend on the degree of sexual divisions and onset of cellularization. Hung-wei Sung, Jörg Grosshans. dimorphism in the tissue and developmental stage in which they are Department of Developmental Biochemistry, Göttingen Center for expressed. Richard Meisel1, John Malone2, Brian Oliver2, Andrew Molecular Biosciences , Göttingen , Niedersachsen, Germany. Clark1. 1) MBG, Cornell Univ, Ithaca, NY; 2) NIDDK, NIH, Bethesda, MD. 63 - 11:30 Developmental Control of the DNA Replication and Transcription 35 - 11:30 Programs. Jared T. Nordman1, Jane Kim1, Noa Sher1, Sharon Li1, Evolutionary analysis of the bag of marbles gene elucidates both David MacAlpine2, Terry L. Orr-Weaver1. 1) Whitehead Institute and intraspecific function and the consequences of interspecific divergence. Dept. of Biology, MIT, Cambridge, MA 02142; 2) Dept. of Heather A. Flores, Daniel A. Barbash, Charles F. Aquadro. Dept Pharmacology and Cancer Biology, Duke University Medical Center, Molec Biol & Gen, Cornell Univ, Ithaca, NY. Durham, NC 27710. 36 - 11:45 64 - 11:45 The two faces of sperm evolution: Insights from analysis of six Apoptosis negatively regulates necrosis in Drosophila. Yong Yang, Lin Drosophila sperm proteomes. Timothy Karr1, Elizabeth Wasbrough2, Hou, Meng Yang, Lei Liu. Peking University, Beijing, China. Steve Dorus2. 1) Biodesign Inst, PO Box 875001, Arizona State Univ, Tempe, AZ; 2) Department of Biology and Biochemistry, University of 65 - 12:00 Bath, Claverton Down, Bath, UK BA2 7AY. The role of mitochondrial dynamics in Drosophila apoptosis. Eltyeb Abdelwahid1, Michael Thomenius2, Christopher Freel2, Sarah 37 - 12:00 Horn2, Ronald Krieser1, Rachel Cannon1, Sujatha Balasundaram1, Phenomics, Transcriptomics, and Metabolomics of Genotype-by-Diet Sally Kornbluth2, Kristin White1. 1) Cutaneous Biol Research Ctr, Interactions underlying Metabolic Syndrome in Drosophila. Laura K. Massachusetts General Hosp, Charlestown, MA. USA; 2) Department of Reed1, Alison Motsinger-Reif2, David Reif3, Greg Gibson4. 1) Dept. Pharmacology and Cancer Biology, Duke University Medical Center, of Biol. Sci., University of Alabama, Tuscaloosa, AL; 2) BRC, Dept. of Durham, North Carolina 27720 USA. Stat., North Carolina State University, Raleigh, NC; 3) National Center for Computational Toxicology, EPA, Research Triangle Park, NC; 4) 66 - 12:15 School of Biology, Georgia Institute of Technology, Atlanta, GA. Cdk5 and Mekk1 mediate a Pro-Apoptotic Signaling Response to Endoplasmic Reticulum Stress. Min-Ji Kang, Hyung Don Ryoo. Dept 38 - 12:15 Cell Biol, New York Univ Sch Med, New York, NY. Extra genomic copies increase energetic demand. Luke A. Hoekstra, Kristi L. Montooth. Department of Biology, Indiana University, Bloomington, IN 47405, USA.

CONCURRENT PLATFORM SESSIONS FRIDAY, APRIL 1 10:45 am – 12:30 pm Program number is in bold above title. The first author is the presenter. Full abstracts can be found online

Drosophila Models of Human Notes Disease (continued)

Room: Golden West

46 - 10:45 Genome wide screening for modulators of Upd and HopTuml-mediated JAK/STAT pathway signalling at the Sheffield RNAi Screening Facility (SRSF). Martin P. Zeidler, Katherine H. Fisher, Amy Taylor, Stephen Brown. The Sheffield RNAi Screening Facility & Department of Biomedical Science, The University of Sheffield, Sheffield, S10 2TN, UK.

47 - 11:00 The secretory secondary cells of the Drosophila accessory gland exhibit mating-dependent growth and migratory behaviours that modulate male fertility: a new model for prostate cancer? Clive Wilson1, Aaron Leiblich1,2, Luke Marsden1,2, Freddie Hamdy2. 1) Dept Physiology, Anatomy & Gen, Univ Oxford, Oxford, UK; 2) Nuffield Dept of Surgical Sciences, University of Oxford, John Radcliffe Hospital, Headley Way, Oxford, UK.

48 - 11:15 Rabex-5 loss results in dramatic hemocyte overproliferation and melanotic mass formation: a potential tumor suppressor and model for leukemia. Theresa Reimels, Cathie M. Pfleger. Department of Oncological Sciences, Mount Sinai School of Medicine, New York, NY.

49 - 11:30 Mutations in seizure/hERG and KCNQ cause both electrical and morphological remodeling of the Drosophila heart. Karen Ocorr. Development & Aging, Sanford-Burnham Medical Research Institute, La Jolla, CA.

50 - 11:45 Drosophila as a model for amyloids induced cardiac dysfunction. Girish C. Melkani1,2, Rolf Bodmer2, Karen Ocorr2, Sanford I. Bernstein1. 1) Department of Biology, Molecular Biology and SDSU Heart Institutes, San Diego State University San Diego, CA 92182; 2) Development and Aging Program, Sanford-Burnham Institute for Medical Research, La Jolla, CA 92037.

51 - 12:00 Mutation of the planar cell polarity gene, prickle, causes epilepsy from flies to humans. J. Robert Manak1, Salleh Ehaideb1, Levi Stowers2, Hirotaka Tao3, Naoto Ueno3, Jeffrey D. Axelrod4, Diane Slusarski1, Alex Bassuk2. 1) Dept Biol, Univ Iowa, Iowa City, IA; 2) Dept Pediatrics, Univ Iowa, Iowa City, IA; 3) Div Morphogen, Nat Inst Basic Biol, Okazaki, Japan; 4) Dept Pathol, Stanford Univ Sch of Med, Stanford, CA.

52 - 12:15 The mauve eye color gene encodes the homolog of the Chediak-Higashi Syndrom gene and has equivalent phenotypes. Mokhlasur Rahman, Adam Haberman, Charles Tracy, Helmut Kramer. Department of Neuroscience, UT Southwestern Medical Center, Dallas, TX.

CONCURRENT PLATFORM SESSIONS FRIDAY, APRIL 1 4:30 pm – 6:30 pm Program number is in bold above title. The first author is the presenter. Full abstracts can be found online

Neural Physiology and Behavior Chromatin and Epigenetics

Moderators: Subhabrata Sanyal, Emory University, Atlanta, Georgia and Moderators: Lori Wallrath, University of Iowa, Iowa City and Keith Carsten Duch, Arizona State University, Tempe Maggert, Texas A&M University, College Station Room: Town & Country Room: Golden West

67 - 4:30 75 - 4:30 The synaptic vesicle-associated Ca2+ channel Flower couples synaptic The CCCTC-binding Factor (CTCF) of Drosophila Contributes to the exo-endocytosis cycle and regulates synaptic growth. Chi-Kuang Regulation of the Ribosomal DNA and Nucleolar Stability. Paola A. Yao1,2, Yong Qi Lin1,2, Claire Haueter1,2, Hugo J. Bellen1,2. 1) Dept Guerrero, Keith Maggert. Dept Biol, Texas A & M Univ, College Molecular & Human Gen, Baylor Col Medicine, Houston, TX; 2) Station, TX. 77843. Howard Huges Medical Institute, Baylor Col Medicine, Houston, TX. 76 - 4:45 68 - 4:45 Spatial and temporal dynamics of homologous recombination repair in Dopamine neurons modulate pheromone responses in Drosophila Drosophila heterochromatin. Irene Chiolo1, Aki Minoda1, Serafin U. courtship learning. Krystyna M. Keleman, Jai Y. Yu, Sebastian Colmenares1, Aris Polyzos1, Silvain V. Costes1, Gary H. Karpen1,2. 1) Kruettner, Eleftheria Vrontou, Barry J. Dickson. IMP, Vienna, Genome Biology, LBNL, Berkeley, CA; 2) MCB, UC Berkeley, Austria. Berkeley, CA.

69 - 5:00 77 - 5:00 Neural Circuit Responsible For Aversive Olfactory Memory Retrieval In invadolysin interacts genetically with non-stop, a histone DUB, to play a Drosophila. Julien Séjourné1, Pierre-Yves Plaçais1, Yoshinori Aso2, role in chromatin modification in Drosophila melanogaster. Margarete Igor Siwanowicz2, Stevanus R. Tedjakumala2, Guillaume Isabel1, M. S. Heck, Michal M. Janiszewski, Shubha Gururaja Rao, Edward Kei Ito3, Paul Tchénio1, Hiromu Tanimoto2, Thomas Preat1. 1) Duca. Ctr Cardiovascular Sci, QMRI, Univ Edinburgh, Edinburgh, Genes and Dynamics of Memory Systems, Neurobiology Unit, ESPCI, United Kingdom. CNRS, PARIS, France; 2) Max-Planck-Institut fur Neurobiologie, Am Klopferspitz 18, D-82152, Martinsried, Germany; 3) Insitute of 78 - 5:15 Molecular and Cellular Biosciences, The University of Tokyo, Bunkyo- Loss of Suppressor of Hairy-wing protein affects nuclear organization ku, Tokyo 113-0032, Japan. and gene expression during Drosophila oogenesis. Alexey A. Soshnev1, Ryan M. Baxley1, Kyle A. Nilson1, Kai Tan2, Bing He2, Pamela K. 70 - 5:15 Geyer1,3. 1) Molec & Cellular Biol, Univ Iowa, Iowa City, IA; 2) Functional organization of the neural circuitry for male courtship Internal Medicine, Univ Iowa, Iowa City, IA; 3) Biochemistry Dept, behavior in Drosophila. Yufeng Pan, Carmen Robinett, Brian Dias, Univ Iowa, Iowa City, IA. Bruce Baker. HHMI: Janelia Farm Research Campus, Ashburn, VA. 79 - 5:30 71 - 5:30 Comparing enhancer action in cis and in trans. Jack R. Bateman, The transcription factor Mef2 links the central circadian clock to Justine E. Johnson. Biology Department, Bowdoin College, neuronal remodeling. Anna Sivachenko, Katharine Abruzzi, Michael Brunswick, ME. Rosbash. Dept Biol, Brandeis Univ, Waltham, MA. 80 - 5:45 72 - 5:45 Histone variant H3.3A represses Notch signaling by activating Remote control of Drosophila behavior using Designer Receptors Suppressor of Hairless. Allison Schaaf1, Kyle Webster1, Ellen Exclusively Activated by Designer Drugs (DREADDs). Charles D. Goodall1, Kami Ahmad2, Brian DeDecker1. 1) MCD Biology, Nichols1, Jaime Becnel1, Oralee Johnson1, Bangning Yu1, Bryan L. University of Colorado, Boulder, CO; 2) Department of BCMP, Harvard Roth2. 1) Dept Pharm, LSU Hlth Sci Ctr, New Orleans, LA; 2) Dept Medical School, Boston, MA. Pharm, UNC Med School, Chapel Hill, NC. 81 - 6:00 73 - 6:00 The role of Pleiohomeotic and Pleiohomeotic-like in Polycomb Expanding the Olfactory Code in Drosopihla by in Silico Decoding of repression. Yuri B. Schwartz1,2, Tatyana G. Kahn1,2, Per Stenberg1, Receptor-Odor Chemical Space. Sean M. Boyle1, Shane McInally2, Vincenzo Pirrotta2. 1) Dept Mol Biol, Umeå University, Sweden; 2) Sana Tharadra2, Anandasankar Ray1,2. 1) Genetics Genomics, and Dept Mol Biol & Biochem, Rutgers University, NJ. Bioinformatics, University Of California, Riverside, CA; 2) Department Of Entomology, University of California, Riverside, CA. 82 - 6:15 Autoregulation of the large noncoding roX1 RNA gene to target 74 - 6:15 chromatin modifications of the Drosophila male X chromosome. Chiat Dietary restriction improves neurotransmission at an adult NMJ in Koo Lim, Richard Kelley. Department of Developmental Biology, dynactin complex mutant flies. Joel Rawson1,2, Holly Davison1, Tabita Baylor College of Medicine, Houston, TX. Kreko1, Rebekah Mahoney1, Leo Chang1,2, Alex Bokov2, Jonathan Gelfond2, Gregory Macleod1, Benjamin Eaton1,2. 1) Dept. of Physiology, UTHSCSA, San Antonio, TX; 2) Barshop Institute for Aging and Longevity Studies, UTHSCSA, San Antonio, TX.

CONCURRENT PLATFORM SESSIONS FRIDAY, APRIL 1 4:30 pm – 6:30 pm Program number is in bold above title. The first author is the presenter. Full abstracts can be found online

Cell Biology and Cytoskeleton Notes

Moderators: Anna Marie Sokac, Baylor University, Waco, Texas and Tom Hays, University of Minnesota, Minneapolis Room: California

83 - 4:30 Asymmetric MBC function and F-actin formation in myoblast fusion. Claude Shelton IV1, Shruti Haralalka1, Heather Cartwright1, Susan Abmayr1,2. 1) Stowers Institute for Medical Research, Kansas City, Missouri; 2) Dept. of Anatomy and Cell Biology, University of Kansas School of Medicine, Kansas City, Kansas.

84 - 4:45 The Drosophila homolog of Arfaptin2 (Darf2) is a novel dynactin complex associated protein required for normal synapse growth, but not axonal transport. Leo Y. Chang, Yimin Wu, Benjamin A. Eaton. Physiology, UT Health Science Center at San Antonio, San Antonio, TX.

85 - 5:00 Identification of Mist, a GPCR involved in epithelial morphogenesis downstream of Folded gastrulation (Fog). Alyssa J. Manning, Kim Peters, Stephen L. Rogers. Biology Department, UNC-Chapel Hill, Chapel Hill, NC.

86 - 5:15 Control of Gastrulation and Epithelial Cell Polarity by the E3 Ubiquitin Ligase Neuralized. Soline Chanet, Véronique Mayau, François Schweisguth. Institut Pasteur - CNRS URA 2578, Paris, France.

87 - 5:30 Regulation of Somatic Myosin Activity by Protein Phosphatase 1beta Controls Drosophila Oocyte Polarization. Yi Sun1,2, Yan Yan1,2, Natalie Denef1,2, Trudi Schupbach1,2. 1) Department of Molecular Biology, Princeton University, Princeton, NJ; 2) Howard Hughes Medical Institute.

88 - 5:45 Role of a Kinesin-3 in Dendrite Morphogenesis. Ann Y. N. Goldstein1,2, Xuyen M. Ho1, Thomas L. Schwarz1,2. 1) Children's Hospital, Boston, F.M. Kirby Neurobiology Center, Boston, MA; 2) Harvard Medical School, Department of Neurobiology, Boston, MA.

89 - 6:00 Anisotropic apical membrane growth mediated by Src42 and dDaam is required for tracheal tube elongation. Kevin S. Nelson1, Zia Khan2, Mona Singh2, Matthias Kaschube2, Greg J. Beitel1. 1) Molecular Biosciences, Northwestern University, Evanston, IL; 2) Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ.

90 - 6:15 Subapical targeting of Zona Pellucida proteins . Francois Payre1,2, Helene Chanut1,2, Ines Gonzalez1,2, Laurence Dubois1,2, Yvan Latapie1,2, Serge Plaza1,2. 1) Centre Biologie du Developpement, University of Toulouse, UPS, Toulouse, France; 2) CNRS, UMR5547, Toulouse, France.

CONCURRENT PLATFORM SESSIONS SATURDAY, APRIL 2 8:30 am – 10:15 am Program number is in bold above title. The first author is the presenter. Full abstracts can be found online

Gametogenesis and Regulation of Gene Expression Organogenesis

Moderators: Sharon Bickel, Dartmouth College, Hanover, New Moderators: Judy Kassis, NIH, Bethesda, Maryland and Pam Geyer, Hampshire and Mary Lilly, NIH/NICHD, Bethesda, Maryland University of Iowa, Iowa City Room: Town & Country Room: Golden West

91 - 8:30 105 - 8:30 Tissue elongation requires oscillating contractions of a basal actomyosin Activation of the germline transcriptional program in Drosophila. network. Li He, Xiaobo Wang, Ho Lam Tang, Denise Montell. Saskia Houwing, Samuel P. Newbold, Ruth Lehmann. Biological Chemistry, Johns Hopkins Univ, Baltimore, MD. Developmental Genetics, Skirball Institute, NYU School of Medicine, New York, NY. 92 - 8:45 Nuclear hormone receptor Hr39 functions as a master regulator of 106 - 8:45 female reproductive gland formation. Jianjun Sun, Allan Spradling. Exploring the Divergence of Species-Specific Gene Expression Patterns Department of Embyology, Carnegie Institution for Science, Howard in Drosophila Embryos. Zeba Wunderlich1, Kelly Eckenrode1, Hughes Medical Institution, Baltimore, MD. Meghan Bragdon1, Charless Fowlkes2, Tara Martin1, Sivanne Pearl1, Angela DePace1. 1) Systems Biology, Harvard Medical School, 93 - 9:00 Boston, MA; 2) Computer Science, UC Irvine, Irvine, CA. Lis-1 and asunder cooperate to regulate dynein localization during Drosophila spermatogenesis. Poojitha Sitaram1, Michael A. 107 - 9:00 Anderson1,2, Laura A. Lee1. 1) Department of Cell and Developmental Two Non-overlapping Enhancers Regulate broad Expression in Biology, Vanderbilt University Medical Center, Nashville, TN; 2) Response to EGFR Signaling. Lily S. Cheung Chang1, Alisa Fuchs2, Department of Biological Chemistry, Center for Cell Dynamics, Johns Giorgos Pyrowolakis2, Stanislav Y. Shvartsman1. 1) Chemical and Hopkins School of Medicine, Baltimore, MD. Biological Engineering, Princeton University, Princeton, NJ, USA; 2) Institute for Biology I, Albert Ludwigs University of Freiburg, Freiburg, 94 - 9:15 Germany. PAPI, a Novel TUDOR-Domain Protein, Complexes with AGO3, ME31B and TRAL in the Nuage to Silence Transposition. Li Liu, 108 - 9:15 Hongying Qi, Jianquan Wang, Haifan Lin. Yale Stem Cell Center and Synthetic enhancers in transgenic flies test 'grammar' hypotheses. Department of Cell Biology, Yale University, New Haven, CT. Richard W. Lusk1, Holli A. Weld2, Michael B. Eisen1,2. 1) Department of Molecular & Cell Biology, UC Berkeley, Berkeley, CA; 2) Howard 95 - 9:30 Hughes Medical Institute, UC Berkeley, Berkeley, CA. Global tissue rotation polarizes a fibrillar Collagen IV matrix to control elongation of the Drosophila egg. Saori L. Haigo, David Bilder. 109 - 9:30 Department of Molecular & Cell Biology, University of California, The regulatory specificity of a homeodomain protein is determined by Berkeley, Berkeley, CA. unique DNA binding sequences. B. W. Busser1, L. Shokri2, S. A. Jaeger2, S. S. Gisselbrecht2, A. Singhania1, M. Berger2, B. Zhou2, M. 96 - 9:45 L. Bulyk2, A. M. Michelson1. 1) National Heart, Lung and Blood Investigating the role for the Ste20-like kinase Misshapen in egg Institute, Bethesda, MD; 2) Division of Genetics, Brigham & Women’s chamber elongation and integrin regulation. Lindsay K. Lewellyn, Sally Hospital, Boston, MA. Horne-Badovinac. University of Chicago, Chicago, IL. 110 - 9:45 97 - 10:00 RB and CAP-D3 co-regulate transcription in Drosophila and human Transcriptional control in the oocyte requires the cohesin-associated cells with important consequences for innate immunity. Michelle S. protein dPds5, which participates in insulator body formation under Longworth1,4, Jim Walker1, Endre Anderssen1, Nam-Sung Moon2, ATM and dChk2 surveillance. Vitor J. Barbosa1, Patricia Silva1, Andrew Gladden1, Margarete M. S. Heck3, Andrea McClatchey1, Raquel Santos1, Ruth Lehmann2. 1) Instituto Gulbenkian de Ciencia, Andre Bernards1, Sridhar Ramaswamy1, Nicholas J. Dyson1. 1) Oeiras, Portugal; 2) Helen L. and Martin S. Kimmel Center for Biology Massachusetts General Hospital Cancer Center and Harvard Medical and Medicine at the Skirball Institute of Biomolecular Medicine. NYU School, Building 149, 13th Street, Charlestown, MA 02144; 2) Langone Medical Center. New York, NY. Department of Biology, Developmental Biology Research Initiative, McGill University, Montreal, Canada; 3) University of Edinburgh, Queen's Medical Research Institute, Centre for Cardiovascular Science; 4) Department of Molecular Genetics, The Lerner Research Institute, Cleveland Clinic , Cleveland, Ohio.

111 - 10:00 Forward genetic analysis of a stage- and tissue-specific hormonal response during Drosophila metamorphosis. Robert Ihry, Arash Bashirullah. Division of Pharmaceutical Sciences & Graduate Program in Cellular and Molecular Biology, University of Wisconsin-Madison, Madison, WI.

CONCURRENT PLATFORM SESSIONS SATURDAY, APRIL 2 8:30 am – 10:15 am Program number is in bold above title. The first author is the presenter. Full abstracts can be found online

Immunity and Pathogenesis Notes

Moderators: David Schneider, Stanford University, Palo Alto, California and Ioannis Eleftherianos, The George Washington University, Washington, DC Room: California

119 - 8:30 The pathways of the pathways; how JAK/STAT, JNK and P38 pathways interact in Drosophila hemocyte activation. Jesper Kronhamn1, Ines Anderl1,2, Jens-Ola Ekström1, AnnaKarin Kronhamn1, Michael Williams3, Dan Hultmark1,2. 1) Umeå University, Umeå, Sweden; 2) University of Tampere, Tampere, Finland; 3) University of Aberdeen, Aberdeen, UK.

120 - 8:45 Multiple requirements of EGFR pathway in maintaining gut homeostasis upon bacterial infection. Nicolas Buchon, Nichole Broderick, Bruno Lemaitre. SV-GHI-UPLEM, EPFL, Lausanne, Switzerland.

121 - 9:00 Drosophila melanogaster as a model organism to study host immune responses to Pseudomonas aeruginosa biofilm infections. Heidi Mulcahy1, Christopher D. Sibley1, Michael G. Surette1,2, Shawn Lewenza1. 1) Department of Microbiology & Infectious Diseases; 2) Department of Biochemistry & Molecular Biology, University of Calgary, Canada.

122 - 9:15 Sick from sex: how mating affects the function and evolution of immune defense in female Drosophila melanogaster. Sarah M. Short, Mariana F. Wolfner, Brian P. Lazzaro. Field of Genetics and Development, Cornell University, Ithaca, NY.

123 - 9:30 Priming caused by S. pneumoniae infection causes changes in gene expression in Drosophila melanogaster. Junaid Ziauddin, David Schneider. Microbiology & Immunology, Stanford Univ SOM, Stanford, CA.

124 - 9:45 Dredd involvement in proximal signaling events in the Drosophila melanogaster IMD pathway. Silvia Guntermann. University of Alberta, Edmonton, AB, Canada.

125 - 10:00 The hostile take-over of insect intracellular niches by Wolbachia pipientis. Harriet L. Harris1,2, Jennifer A. Biliske2, Lesley J. Brennan2. 1) Dept Biol, Concordia Univ Col, Edmonton, AB, Canada; 2) Dept Biological Sciences, University of Alberta, Edmonton, AB Canada.

CONCURRENT PLATFORM SESSIONS SATURDAY, APRIL 2 10:45 am – 12:30 pm Program number is in bold above title. The first author is the presenter. Full abstracts can be found online

Physiology and Aging Gametogenesis and Organogenesis (continued)

Moderators: John Tower, University of Southern California, Los Room: Town & Country Angeles and LeAnne Jones, The Salk Institute for Biological Studies, La Jolla, California 98 - 10:45 Room: California Prostaglandins - major regulators of follicle development. Tina L. Tootle, Andrew Spracklen, Tiffany Fagan. Anatomy and Cell 126 - 10:45 Biology, University of Iowa, Carver College of Medicine, Iowa City, IA. Coordination of Triacylglycerol and Cholesterol Homeostasis by the Drosophila DHR96 Nuclear Receptor. Matt Sieber, Carl Thummel. 99 - 11:00 Dept Human Genetics, University of Utah, Salt Lake City, UT. The JAK/STAT pathway in the development of asymmetry within the Drosophila embryonic hindgut. Richard E. Wells, David I. Strutt, 127 - 11:00 Martin P. Zeidler. MRC CDBG, Dept of Biomedical Science, TSPO, a mitochondrial membrane potential modulator, plays an University of Sheffield, S10 2TN, UK. essential role in Drosophila aging. Ran Lin1,2, Douglas C. Wallace1. 1) Children's Hospital of Philadelphia (CHOP), Philadelphia, PA; 2) 100 - 11:15 Department of Physiology and Pathophysiology, School of Basic Two Forkhead Transcription Factors Mediate both Symmetric and Medical Sciences, Peking University Health Science Center, Beijing, Asymmetric Cell Division during Drosophila Cardiogenesis. Shaad M. China. Ahmad1, Terese Tansey1, Neal Jeffries1, Stephen S. Gisselbrecht2, Alan M. Michelson1. 1) National Heart, Lung, and Blood Institute, 128 - 11:15 Bethesda, MD; 2) Division of Genetics, Dept. of Medicine, Brigham & Stem Cell Response to Nutrient Availability in Drosophila. Lei Wang, Women's Hospital, Boston, MA. Catherine McLeod, Leanne Jones. Laboratory of Genetics, The Salk Institute, La Jolla, CA. 101 - 11:30 Sexual Compatibility Between the Germline and Soma in Drosophila. 129 - 11:30 Sheryl M. Murray, Mark Van Doren. Johns Hopkins University, Characterization of a Hormone Dependent Module Regulating Energy Baltimore, MD. Balance in Drosophila. Biao Wang1,2, Noel Moya1, Sherry Niessen3, Heather Hoover3, John Yates III3, Wolfgan Fischer1, John Thomas2, 102 - 11:45 Marc Montminy1. 1) PBL-M, Salk Inst Biological, La Jolla, CA; 2) Shaping cells and organs through the opposing effects of fat body- MNL-T, Salk Inst Biological, La Jolla, CA; 3) The Center for secreted Collagen IV and Perlecan. Jose C. Pastor-Pareja, Tian Xu. Physiological Proteomics, The Scripps Research Institute, LaJolla CA. Dept Genetics, Yale School of Medicine-HHMI, New Haven, CT.

130 - 11:45 103 - 12:00 dFatp links fatty acid metabolism to lifespan, stress resistance and Proteases in the seminal fluid are necessary for multiple post-mating cardiac function in Drosophila. Joanna M. Jennens, Samantha processes. Brooke A. LaFlamme, Mariana F. Wolfner. Molec Biol & Morley, Nicole Piazza, Li Zheng, Lindsey Healy, Alyson Sujkowski, Gen, Cornell Univ, Ithaca, NY. Robert Wessells. University of Michigan, Ann Arbor, MI. 104 - 12:15 131 - 12:00 Phosphoinositides regulate nuclear shaping and chromatin remodeling PGC-1/spargel is a Modifier of Diet-Induced Fat Accumulation and during Drosophila sperm development. Lacramioara Fabian1, Ho- Associated Heart Defects. Soda Diop, Sean Oldham, Rolf Bodmer. Chun Wei1, Kishan Bellamkonda1, Julie A. Brill1,2. 1) Developmental Development and Aging Program, Sanford Burnham Institute, La Jolla, and Stem Cell Biology, The Hospital for Sick Children, Toronto, CA. Ontario, Canada; 2) Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada. 132 - 12:15 Met tRNAi Synthesis Controls Growth and Development in Drosophila. Elizabeth J. Rideout, Lynne Marshall, Savraj S. Grewal. Clark H. Smith Brain Tumour Centre, Southern Alberta Cancer Research Institute, and Department of Biochemistry and Molecular Biology, University of Calgary, HRIC, 3330 Hospital Drive, Calgary, Alberta, T2N 4N1, Canada.

CONCURRENT PLATFORM SESSIONS SATURDAY, APRIL 2 10:45 am – 12:30 pm Program number is in bold above title. The first author is the presenter. Full abstracts can be found online

Regulation of Gene Expression Notes (continued)

Room: Golden West

112 - 10:45 Polycomb inhibits poised Pol II in the Drosophila embryo. Vivek S. Chopra1, David A. Hendrix2, Leighton J. Core3, Chiahao Tsui1, John T. Lis3, Michael Levine1. 1) Dept Mol & Cell Biol, UC Berkeley, Berkeley, CA; 2) Broad Inst of MIT & Harvard, Cambridge, MA; 3) Cornell University, Ithaca, NY.

113 - 11:00 Spatiotemporal optimization of gap gene regulatory network models to gene atlas data. David M. Umulis, James Hengenius, Ann Rundell, Michael Gribskov. Purdue University, West Lafayette, IN 47907.

114 - 11:15 Non-canonical compensation of zygotic X transcription in early Drosophila melanogaster development revealed through single-embryo RNA-Seq. Susan E. Lott1, Jacqueline E. Villalta2, Leath A. Tonkin3, Michael B. Eisen1,2. 1) Department of Molecular and Cell Biology, University of California, Berkeley; 2) Howard Hughes Medical Institute, University of California, Berkeley; 3) Vincent J. Coates Genomics Sequencing Laboratory, QB3 Institute, University of California, Berkeley.

115 - 11:30 Dissecting the role of the SAGA histone acetyltransferase in tissue- specific gene regulation. Jamie O. Dyer1, Vikki M. Weake1, Ying Zhang1, Laurence Florens1, Michael P. Washburn1,2, Jerry L. Workman1, Susan M. Abmayr1,3. 1) Stowers Institute for Medical Research, Kansas City, MO; 2) Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS; 3) Department of Anatomy and Cell Biology, University of Kansas Medical Center, Kansas City, KS.

116 - 11:45 Evolutionary dynamics of CTCF binding in the Drosophila genome. Xiaochun Ni1,2, Yong Zhang1, Kevin White1,2. 1) Department of Ecology & Evolution, University of Chicago, Chicago, IL; 2) Joint institute for genomics and systems biology, University of Chicago and Argonne National Laboratory, Chicago, IL.

117 - 12:00 Live in toto imaging of patterns of gene expression during Drosophila embryogenesis. Pavel Tomancak. MPI-CBG, Dresden, Germany.

118 - 12:15 A Regulatory Matrix Controlling Selective Odorant Receptor Expression in Drosophila. Mattias Alenius1, Alexander Schleiffer2, Liza Alkhori1, Shadi Jaffari1. 1) Department of Clinical and Experimental Medicine, Linkoping university, Linkoping, Sweden; 2) Research Institute of Molecular Pathology, Vienna, Austria.

CONCURRENT PLATFORM SESSIONS SATURDAY, APRIL 2 4:00 pm – 6:00 pm Program number is in bold above title. The first author is the presenter. Full abstracts can be found online

139 - 5:30 Techniques and Functional Using Drosophila to find transcriptional enhancers in highly diverged arthropod genomes. Marc S. Halfon1, Jia-Yu Chen2, Majid Genomics Kazemian2, Saurabh Sinha2. 1) Dept. of Biochemistry, SUNY at Buffalo, Buffalo, NY; 2) Dept. of Computer Science, University of Moderators: Hugo Bellen, HHMI & Baylor College of Medicine, Illinois at Urbana-Champaign, Urbana, IL. Houston, Texas and Julie Simpson, HHMI Janelia Farm Research Campus, Ashburn, Virginia 140 - 5:45 Room: Town & Country MiMIC (Minos Mediated Integration Cassette): a versatile transposable element for tagging genes in vivo. Koen Venken1, Karen Schulze2, Nele Haelterman1, Hongling Pan2, Yuchun He2, Martha Evans- 133 - 4:00 Holm3, Joseph Carlson3, Bob Levis4, Allan Spradling4, Roger New Challenges, Directions and Approaches in Cell-Based RNAi Hoskins3, Hugo Bellen1,2,5. 1) Department of Molecular and Human Screening: Application of High-Content Imaging to Genome-Scale Genetics, BCM, Houston, TX; 2) HHMI, BCM, Houston, TX; 3) Life Interrogations of the Nucleus. Stephanie E. Mohr1, Julio Mateos- Sciences Division, LBNL, Berkeley, CA; 4) Department of Embryology, Langerak2, Joseph Dopie3, Ralph Neumuller4, Tiao Xie5, Anastasia HHMI, CI, Baltimore, MD; 5) Program in Developmental Biology, Samsonova4, Michelle Ocana1,5, Quentin Gilly1, Benjamin BCM, Houston, TX. MacElvany1, Ian Flockhart1, Matthew Booker1,6, Claire Hu1, Giacomo Cavalli2, Maria Vartiainen3, Norbert Perrimon1,4,7. 1) Drosophila RNAi Screening Center, Harvard Medical School, Boston, MA; 2) Institute of Human Genetics, Montpellier, France; 3) Institute of Biotechnology, University of Helsinki, Finland; 4) Department of Genetics, Harvard Medical School, Boston, MA; 5) ICCB-Longwood Screening Facility, Harvard Medical School, Boston, MA; 6) Division of Biology and Medicine, Brown University, Providence, RI; 7) Howard Hughes Medical Institutes, Harvard Med Sch, Boston, MA. Notes

134 - 4:15 Functional Profiling of Rab GTPases in the Drosophila Nervous System. Chih-Chiang Chan1,4, Shane Scoggin3,4, Dong Wang1, Smita Cherry1, Michael Buszczak3,5, P. Robin Hiesinger1,2,5. 1) Department of Physiology; 2) Green Center for Systems Biology; 3) Department of Molecular Biology, Univ Texas Southwestern Medical Center, Dallas, TX; 4) Co-first authors; 5) Co-corresponding authors.

135 - 4:30 Virtual Fly Brain. David J. Osumi-Sutherland1, Simon R. Reeve1, Nestor Milyaev2, J. Douglas Armstrong2, Michael Ashburner1. 1) Dept Genetics, Cambridge University, Department of Genetics, Cambridge CB2 3EH, UK; 2) Edinburgh University School of Informatics, 10 Crichton Street Edinburgh EH8 9AB, UK.

136 - 4:45 Defining the Drosophila melanogaster protein complex map. Spyros Artavanis-Tsakonas1, Guruharsha Kuthethur1, Jean-François Rual1, Bo Jhai1, Julian Mintseris1, Mark Stapleton2, Rogerio Candeias3,4, David Rhee1, Kadalmani Krishnan1, Christina Wong1, Chapman Beekman1, Kenneth Wan2, Charles Yu2, Xiao Chen2, Manolis Kellis3,4, K. VijayRaghavan5, Steven Gygi1, Susan Celniker2, Robert Obar1. 1) Department of Cell Biology, Harvard Medical School, Boston, MA; 2) BDGP, Lawrence Berkeley National Laboratory, Berkeley, CA; 3) Computer Science and Artificial Intelligence Laboratory, MIT, Cambridge, MA; 4) Broad Institute of MIT and Harvard, Cambridge, MA; 5) National Centre for Biological Sciences, TIFR, Bangalore, India.

137 - 5:00 Flipping In or Out: A Collection of Enhancer-trap Flippase and the FINGR Method for Mosaic Analysis. Talor Fore1, Xinyun Peng1, Audrey Ojwang1, Margaret Warner1, Chelsea Springer1, Rudolf Bohm1,2, William Welch1, Lindsey Goodnight1, Hong Bao1, Bing Zhang1. 1) Department of Zoology, University of Oklahoma, Norman, OK; 2) Department of Biology, Brandeis University, Waltham, MA.

138 - 5:15 Measuring transcription kinetics in vivo with light microscopy. Alistair N. Boettiger1,3, Michael Perry2,3, Michael Levine3. 1) Biophysics Graduate Group,; 2) Dept. Integrated Biology,; 3) Dept. Molecular Biology, Univ California, Berkeley, Berkeley, CA.

CONCURRENT PLATFORM SESSIONS SATURDAY, APRIL 2 4:00 pm – 6:00 pm Program number is in bold above title. The first author is the presenter. Full abstracts can be found online

Stem Cells Cell Biology and Signal Transduction

Moderators: Yukiko Yamashita, University of Michigan, Ann Arbor and Moderators: Yashi Ahmed, Dartmouth Medical School, Hanover, New Craig Micchelli, Washington University, St. Louis, Missouri Hampshire and Michael Welte, University of Rochester, New York Room: Golden West Room: California

141 - 4:00 149 - 4:00 Brain tumor promotes differentiation and suppresses de-differentiation A tale of three kinases: Autophagy regulation by Class II PI3-kinase. in neural progenitor cells. Cheng-Yu Lee1,2,3, Hideyuki Komori1. 1) Michaella M. Velichkova, Pavan Kadandale, Amy Kiger. Div Center for Stem Cell biology, Life Sci. Inst.; 2) Div. of Mol. Med. and Biological Sci, Univ California San Diego, La Jolla, CA. Gen., Dep of Int. Med; 3) Dep. of Cell and Dev. Biol., University of Michigan Medical School, Ann Arbor, MI 48109. 150 - 4:15 Eye transformer is a negative regulator of Drosophila JAK/STAT 142 - 4:15 signaling. Henna Myllymäki1, Jenni Kallio1, Juha Grönholm2, Morag Cyst stem cell development and regulation of germline stem cell Armstrong1, Leena-Maija Vanha-aho1, Leena Mäkinen1, Olli maintenance during Drosophila testes morphogenesis. Matthew Silvennoinen2, Mika Rämet1,3. 1) Laboratory of Experimental Wawersik1, Matthew Badgett1, Jake Fry1, Erika Matunis2, Rebecca Immunology, Institute of Medical Technology, University of Tampere, Obniski1, Xuteng Sheng2, Amanda Simmons1, Daniel Sinden1. 1) Tampere, Finland; 2) Laboratory of Molecular Immunology and Biology Dept, College of William & Mary, Williamsburg, VA; 2) Dept Cytokine Receptor Signaling, Institute of Medical Technology, of Cell Biology, Johns Hopkins School of Medicine, Baltimore, MD. University of Tampere, Tampere, Finland; 3) Department of Pediatrics, Tampere University Hospital, Tampere, Finland. 143 - 4:30 Mitochondrial dynamics in larval neuroblasts. Rachel T. Cox1,2, Aditya 151 - 4:30 Sen1, Vanessa T. Damm2. 1) Department of Biochemistry and Wnt-4 Binds PTK7/Otk Inhibiting Canonical Signal Transduction. Molecular Biology; 2) Center for Neuroscience and Regenerative Nicholas S. Tolwinski. Dev Biol, Sloan Kettering Inst, New York, NY. Medicine, Uniformed Services University, Bethesda MD. 152 - 4:45 144 - 4:45 Hipks Stabilize -catenin/Armadillo through Inhibition of SCF-TrCP/Slimb- The Drosophila Pez phosphatase restricts intestinal stem cell mediated Ubiquitination. Sharan Swarup, Wendy Lee, Joanna Chen, proliferation via Hippo signaling. Ingrid Poernbacher, Roland Esther Verheyen. Molecular Biology & Biochemistry, Simon Fraser Baumgartner, Ernst Hafen, Hugo Stocker. Institute of Molecular University, Burnaby, British Columbia, Canada. Systems Biology, ETH Zürich, Wolfgang-Pauli-Strasse 16, 8093 Zürich, Switzerland. 153 - 5:00 The deubiquitinase enzyme USP36/SCNY regulates selective p62- 145 - 5:00 dependent autophagy in Drosophila and in human cells. Emmanuel Follicle stem cells have a unique polarity that regulates niche Taillebourg1, Dominique Thevenon1, Isabel Gregoire2, Mathias competition. Todd G. Nystul1, Maria R. Kronen1, Kevin E. Faure2, Marie-Odile Fauvarque1. 1) IRTSV, CEA, Grenoble, France; Schoenfelder1, Allan C. Spradling2. 1) Anatomy Dept., UC San 2) INSERM U851, Université Lyon 1, Lyon, France. Francisco, San Francisco, CA; 2) HHMI/Carnegie Institution, Dept. of Embryology, Baltimore, MD. 154 - 5:15 The complex nature of Notch pathway regulation by O-glucose residues 146 - 5:15 on Notch. Jessica Leonardi1, Rodrigo Fernandez-Valdivia4, Nadia A. Steroid hormone ecdysone signaling is required for germline Rana2, Yi-Dong Li4, Amanda Simcox3, Robert S. Haltiwanger2, differentiation. Annekatrin Klepzig, Andriy Yatsenko, Miriam Hamed Jafar-Nejad1,4. 1) Program in Developmental Biology, Baylor Weiss, Halyna Shcherbata. Gene expression and Signaling group, College of Medicine, Houston, TX; 2) Stony Brook University, Stony Max-Planck Institute for Biophysical Chemistry, Göttingen, Germany. Brook, NY; 3) Ohio State University, Columbus, OH; 4) IMM, UT Health Science Center, Houston, TX. 147 - 5:30 Chromosome Strand Segregation During Drosophila Male Germline 155 - 5:30 Stem Cell Division. Swathi Yadlapalli, Yukiko Yamashita. Dept of Visualizing physically interacting Wg pathway components in vivo. Cell and Developmental Biology, Life Sciences Institute, University of Marcel Wehrli1, Amber Jones-Hackathorne1, David Roberts2,3, Michigan, Ann Arbor, MI. Mark Peifer2. 1) Cell & Dev Bio, OHSU, Portland, OR; 2) Biology, UNC, Chapel Hill, NC; 3) Franklin & Marshall Coll., Lancaster, PA. 148 - 5:45 Imaging BMP receptor activation at an adherens junction associated 156 - 5:45 stem cell niche synapse. Christian Boekel, Marcus Michel, Isabel Role of Monosaccharide O-fucose modification of Notch for the folding Raabe, Raquel Perez Palencia, Adam Kupinski. CRTD, TU Dresden, of the Notch receptor in Drosophila. Akira Ishio1, Tomonori Dresden, Germany. Ayukawa1, Naoki Aoyama1, Tetsuya Okajima2, Kenji Matsuno1. 1) Department of Biological Science and Technology, Tokyo University of Science, Chiba, Japan; 2) Nagoya University Graduate School of Bioagricultural Sciences, Department of Applied Molecular Biosciences.

POSTER SESSIONS See page 16 for presentation schedule Poster board number is in bold above title. The first author is the presenter. Full abstracts can be found online at drosophila-conf.org

167B Cell Biology and Signal The Drosophila Planar Polarity Gene Multiple Wing Hairs interacts with diaphanous to Locally Inhibit the Actin Cytoskeleton. Qiuheng Lu, Transduction Paul Adler. Biology Department, Department of Cell Biology, Morphogenesis and Regenerative Medicine Institute and Cancer Center, 157A University of Virginia, Charlottesville, Virginia. Generating a suite of endogenously-expressed, EGFP-tagged core proteins to study the dynamics of planar polarity establishment in vivo. 168C Jessica Allen, Samantha Warrington, David Strutt. Department of Planar cell chirality contributes to left-right asymmetric epithelial Biomedical Science, University of Sheffield, Sheffield, South Yorkshire, morphogenesis in Drosophila. Reo Maeda1,3, Kiichiro Taniguchi1,3, United Kingdom. Tadashi Ando1, Naotaka Nakazawa1, Ryo Hatori1, Mitsutoshi Nakamura1, Takashi Okumura1, Kenji Matsuno1,2. 1) Dept. Biol. 158B Sci./Tech., Tokyo Univ. of Sci; 2) Res. Ins. Sce./Tech., Tokyo Univ. of Role of the Drosophila Phosphatidylinositol-4-kinase Four Wheel Sci; 3) Equal contribution. Drive in Planar Cell Polarity. Sophie M. Balmer, Ursula Weber, Marek Mlodzik. Dept of Developmental and Regenerative Biology, 169A Mount Sinai School of Medicine, New York, NY. Study of a new epithelial polarity pathway. Vincent Mirouse1, Dan Bergstralh2, Caroline Vachias1, Daniel St. Johnston2. 1) GReD, 159C CNRS, INSERM, Clermont University, Clermont-ferrand, France; 2) Cracking the Prickle Isoform Code. Simon Collier, Justin Hogan, The Wellcome Trust Gurdon institute, Cambridge University, UK. Meagan Valentine, Jessica Layne, Charles Davis, Zachery Kuhl. Dept Biological Sci, Marshall Univ, Huntington, WV. 170B Asymmetric cell signaling: new lessons learned from symmetry 160A breaking of EGFR signaling during bract cell fate determination in Lethal giant larvae (Lgl) promotes neural stem cell differentiation by Drosophila. Ying Peng, Jeff Axelrod. Dept. of Pathology, Stanford antagonizing Notch. Jill Haenfler1,2, Cheng-Yu Lee2,3,4. 1) Graduate University School of medicine, Stanford, CA. Program in Cellular and Molecular Biology; 2) Center for Stem Cell Biology, Life Sciences Institute; 3) Cell and Developmental Biology; 4) 171C Division of Molecular Medicine & Genetics, Dept of Internal Medicine, Analysis of the Crumbs-Yurt interaction in the organization of Univ of Michigan, Ann Arbor, MI. Drosophila photoreceptor cells. David ter Stal1, Juan Huang2, Yang Hong2, Ulrich Tepass1. 1) Cell and Systems Biology, University of 161B Toronto, Toronto, Ontario, Canada; 2) Department of Cell Biology and Macroglobulin complement related (Mcr) is required for tracheal Physiology, University of Pittsburgh, Pittsburgh, Pennyslvania. morphogenesis and septate junction function during embryogenesis and imaginal disc morphogenesis during metamorphosis. Sonia Hall, Bone 172A Courtney, Robert Ward. Molecular Biosciences, University of Kansas, Mapping muscle myosin relay loop-converter domain interactions by Lawrence, KS. site-directed mutagenesis and suppressor analysis. Sanford I. Bernstein, William A. Kronert, Girish C. Melkani, Anju Melkani. 162C Dept Biol, San Diego State Univ, San Diego, CA. Examining the role of Rap1 in regulating the actin cytoskeleton and apical polarity. Nathan J. Harris1, Mark Peifer1,2. 1) Biology, UNC- 173B Chapel Hill, Chapel Hill, NC; 2) Lineberger Comprehensive Cancer Actin dynamics in larval epidermal wound closure. Amanda R. Brock1, Center, UNC-Chapel Hill, Chapel Hill, NC. Yan Wang1, Susanne Berger2, Yujane Wu1, Renate Renkawitz- Pohl2, Michael J. Galko1. 1) Biochem & Mol Bio, UT MD Anderson 163A Cancer Center, Houston, TX; 2) Philipps-Universität Marburg, Marburg, Novel Kinases regulating Wnt/-Catenin and Fz/planar cell polarity Germany. signaling. Andreas Jenny1, Ekatherina Serysheva2, Hebist Berhane1, Kubilay Demir3, Michael Boutros3, Marek Mlodzik2. 1) Department 174C of Molecular & Developmental Biology, Albert Einstein College of AIP1-mediated Actin Dynamics is Essential for Adherens Junction Medicine, New York, NY; 2) Department of Developmental and Rearrangement during Epithelial Morphogenesis in the Drosophila Eyes. Regenerative Biology, Mount Sinai School of Medicine, New York, Dandan Chu, Ping Wan, Jiong Chen. Model Animal Research Center, NY; 3) Signaling and Functional Genomics, German Cancer Research Nanjing University, 12 Xue Fu Road Nanjing, China 210061. Center, Heidelberg, Germany. 175A 164B Integrin function is developmentally regulated through distinct The function of the Bazooka-aPKC interaction for the establishment of interactions with talin. Stephanie J. Ellis, Mary Pines, Michael J. cell polarity in Drosophila. Michael P. Krahn, Andreas Wodarz. Stem Fairchild, Guy Tanentzapf. Cellular and Physiological Sciences, Cell Biology, University Goettingen, Goettingen, Germany. University of British Columbia, Vancouver, BC, Canada.

165C 176B Role of DaPKC in the organization of the Follicular Epithelium of the Overlapping regulation of Myosin Regulatory Light Chain Drosophila egg chamber. Anabel R. Learte1, Sol Sotillos2, Rosario phosphorylation and tissue morphogenesis by Drosophila Drak and Rok Hernández1, Sonsoles Campuzano1. 1) Centro de Biología Molecular kinases. David R. Hipfner1,2,3, Dagmar D. A. Neubueser1. 1) Institut Severo Ochoa, CSIC-UAM , Madrid, Spain; 2) Centro Andaluz de de recherches cliniques de Montréal (IRCM), Montréal, QC, Canada; 2) Biologia del Desarrollo, CSIC-UPO, Sevilla, Spain. Département de Médicine, Université de Montréal, Montréal, QC, Canada; 3) Department of Anatomy & Cell Biology, McGill University, 166A Montreal, QC, Canada. Heavy-spectrin is part of a feedback loop in the regulation of the apical domain by Rac1. Seung-kyu Lee, Graham Thomas. Dept Biochem & Molec Bio, Pennsylvania State Univ, University Park, PA.

POSTER SESSIONS See page 16 for presentation schedule Poster board number is in bold above title. The first author is the presenter. Full abstracts can be found online at drosophila-conf.org

177C Membrane and Cytoskeleton Responses during Single Cell and The LIM protein PINCH suppresses defects associated with mutations in Multicellular Wound Repair in Drosophila. Jeffrey M. Verboon, Maria the myosin phosphatase flapwing. Julie L. Kadrmas1,2, Stephen M. Teresa Abreu-Blanco, Raymond Liu, Susan Parkhurst. Fred Pronovost2, Mary C. Beckerle1,2,3. 1) Department of Oncological Hutchinson Cancer Research Center, Seattle, WA. Sciences; 2) Huntsman Cancer Institute; 3) Department of Biology, University of Utah, Salt Lake City, UT. 188B Egfr interacts with Dpp signaling during dorsal closure. Xi Chen1, 178A Weiping Shen2, Nicholas Harden1. 1) Molecular Biology and H-spectrin and Annexin B9 have roles in protein recycling and Biochemistry, Simon Fraser University, Burnaby, B.C., Canada; 2) multivesicular body function in Drosophila. Mansi R. Khanna1, Laboratory of Genetics, National Institute on Aging, NIH Biomedical Monika Tjota2, Seung-Kyu Lee2, Juan Wu2, Janice A. Williams3, Research Center, Baltimore, MD. Graham H. Thomas1,2. 1) Dept Biol, Penn State Univ, State College, PA; 2) BMB, Penn State Univ, State College, PA; 3) Vanderbilt Univ 189C Med Center, Surgical Research, Nashville, TN. Mummy Mediates Embryonic Dpp Signal Restriction. Gregory B. Humphreys, Kate Monroe, Anthea Letsou. Human Gen, Univ Utah, 179B Salt Lake City, UT. Dynamic expression and the asymmetric distribution of the homophilic cell adhesion molecule Echinoid controls the polarization of the actin 190A cytoskeleton. Arsida Noçka1, Caroline Laplante1,2, Laura Nilson1. 1) The role of the JNK signaling antagonist, Raw, during Drosophila dorsal Department of Biology, McGill University, Montreal, Canada; 2) closure. Molly C. Jud, Melissa Ratcliffe, Gregory B. Humphreys, Molecular, Cell and Developmental Biology, Yale University, New Anthea Letsou. Department of Human Genetics, University of Utah, Haven, CT. Salt Lake City, UT.

180C 191B Roles of Ena/VASP and Capping Protein in Drosophila development. Wishful thinking regulates BMP signaling in the Drosophila follicular Stephanie Nowotarski1, Julie Gates2, Mark Peifer1. 1) Biology, Univ epithelium. Rob Marmion, Nir Yakoby. Biology Department and North Carolina, Chapel Hill, NC; 2) Biology Dept, Bucknell University, Center for Computational and Integrative Biology, Rutgers, The State Lewisburg, PA. University of New Jersey, Camden, NJ 08102.

181A 192C Screening chromosome 2R for regions that genetically interact with Abl Proteomics of Multi Vesicular Body (MVB) sorting deficient endosomes kinase during cell migration. Kristina Reiss, Christopher Moline, in Drosophila melanogaster. Ambra Bianco, Thomas Vaccari. FOM - Caron Leonard, Traci L. Stevens. Dept. of Biology, Randolph-Macon FIRC Institute of Molecular Oncology via Adamello 16 20139 Milano. College, Ashland, VA. 193A 182B The role of V-ATPase in Notch trafficking and signaling activation. Somatic myoblast fusion in Drosophila is independent of -Tubulin Serena Duchi, Thomas Vaccari. IFOM - FIRC Institute of Molecular isotypes, while two non-muscle myosins are required in redundancy as Oncology. actin motor proteins. Anja Rudolf1, Bettina Bonn2, Detlev Buttgereit1, Renate Renkawitz-Pohl1. 1) Developmental Biology, University of 194B Marburg, Germany; 2) Pediatric Hematology and Oncology, University Identification of GAP proteins regulating RAB11 during development. hospital of Gieen, Germany. Carl Laflamme, Jonas Dorn, Paul Maddox, Gregory Emery. Research Institute for Immunology and Cancer (IRIC), Montréal, 183C Quebec, Canada. Identifying and characterizing novel Drosophila Zasp isoforms. Frieder B. Schoeck, Byeo Ri Lee, Jenny Long. Dept Biol, McGill Univ, 195C Montreal, PQ, Canada. A gradient of apical endocytosis shapes the apical surface of the early embryo. Aleksandar S. Necakov, Piotr Fabrowski, Stefano De 184A Renzis. Developmental Biology Unit, The European Molecular Biology Role of Moesin in maintaining Ecadherin in the late-stage follicular Laboratory, Heidelberg, Germany. epithelium. Kristin Sherrard, Richard Fehon. Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL. 196A Phosphoinositide roles in muscle membrane compartmentalization and 185B remodeling. Ines Ribeiro, Amy Kiger. Division of Biological Sciences, A Drosophila high-content genome-wide RNAi screen identifies novel University of California, San Diego, La Jolla, CA. conserved regulators of the actin cytoskeleton. David Sims1, Jennifer Rohn2, Tao Liu2, Marina Fedorova2, Frieder Schoeck3, Maria 197B Vartiainen4, Amy Kiger5, Norbert Perrimon6, Buzz Baum2. 1) The Chmp1 protein controls wing vein development. Meagan Valentine1, Institute of Cancer Research, London, UK; 2) MRC Laboratory for Maiyon Park2, Simon Collier1. 1) Marshall University, Huntington, Molecular Cell Biology, University College London, UK; 3) Department WV; 2) Marshall University School of Medicine, Huntington, WV. of Biology, McGill University, Montreal, Canada; 4) Institute of Biotechnology, University of Helsinki, Finland; 5) Division of 198C Biological Sciences, University of California, San Diego, CA; 6) Non-autonomous and context-dependent control of apoptosis by Department of Genetics, Harvard Medical School, Boston, MA. deregulated Hedgehog signaling. Andreas Bergmann, Yun Fan, Tian Ding, Audrey Christiansen. Dept Biochem & Molec Biol, MD 186C Anderson Cancer Ctr, Houston, TX. A role for Slik in regulating apical membrane integrity and growth of terminal branches in the tracheal system. Fiona P. Ukken1,2, Maria Leptin1,2, Nair Jayanandanan2. 1) University of Cologne, Cologne, Germany; 2) EMBL, Heidelberg, Germany. 187A 45

POSTER SESSIONS See page 16 for presentation schedule Poster board number is in bold above title. The first author is the presenter. Full abstracts can be found online at drosophila-conf.org

199A 209B Ihog and Boi are essential for Hedgehog signaling in Drosophila. Klar interacts physically with Kinesin-1 and Dynein and is involved in Darius Camp1,2,3, Ko Currie3, Alain Alain Labbé3, Donald van pole plasm assembly during oogenesis. Michael A. Welte1, Yanxun V. Meyel3, Frédéric Charron1,2. 1) Experimental Medicine, McGill Yu1, Sean L. Cotton2. 1) Dep Biol, Univ Rochester, Rochester, NY; 2) University, Montreal, Qc, Canada; 2) Molecular Biology of Neural Dep Biomed Eng, Boston Univ, Boston, MA. Development, IRCM, Montreal, QC, Canada; 3) Centre for Research in Neuroscience, MUHC, Montreal, Qc, Canada. 210C Guidance Receptor Degradation Is Required for Neuronal Connectivity 200B in the Drosophila Nervous System. W. Ryan Williamson1, Taehong G protein-coupled receptor kinase 2 promotes high-level Hedgehog Yang2, Jonathan R. Terman2, P. Robin Hiesinger1. 1) Dept signaling by regulating the active state of Smo through kinase-dependent Physiology and Green Center for Systems Biology, UT Southwestern and kinase-independent mechanisms in Drosophila. Yongbin Chen1, Med Ctr, Dallas, TX; 2) Dept Neuroscience and Pharmacology, UT Shuang Li1, Chao Tong1, Yun Zhao1, Bing Wang1, Yajuan Liu2, Southwestern Med Ctr, Dallas, TX. Jianhang Jia2, Jin Jiang1. 1) Department of Developmental Biology, University of Texas Southwestern Medical Center at Dallas, Dallas, 211A Texas 75390, USA; 2) Markey Cancer Center, University of Kentucky, The interaction between two JAK signaling ligands: Upd and Upd3. Lexington, Kentucky 40536, USA. Qian Chen, Shanshan Pei, Douglas Harrison. Dept Biol, Univ Kentucky, Lexington, KY. 201C Temporal regulation of lipid-droplet transport via Halo. Gurpreet K. 212B Arora, Susan L. Tran, Nicholas P. Rizzo, Michael A. Welte. A molecular characterisation of the JAK/STAT pathway receptor Department of Biology, University of Rochester, Rochester, NY. Domeless. Katherine H. Fisher1, Wojciech Stec1, Amy Taylor1,2, Stephen Brown1,2, Martin P. Zeidler1. 1) The MRC Centre for 202A Developmental & Biomedical Genetics, Dept of Biomedical Science, Schizo/Loner functions as an unconventional GEF for the Arf1-GTPase. University of Sheffield, UK; 2) Sheffield RNAi Screening Facility, Dept Verena Groth, Christine Dottermusch, Renate Renkawitz-Pohl, of Biomedical Science, University of Sheffield, UK. Susanne-Filiz Önel. Philipps-Universität Marburg, Marburg, Hessen, Germany. 213C Regulation of a STAT signaling circuit that mediates border cell 203B determination and migration. Amanda J. Monahan, Michelle Starz- Kosh accumulates at the prefusion complex stage during Drosophila Gaiano. University of Maryland, Baltimore County, Baltimore, MD. myoblast fusion. Christina Hornbruch1, Barbara Griemert1,2, Detlev Buttgereit1, Renate Renkawitz-Pohl1. 1) Developmental Biology, 214A Philipps-Universität Marburg, 35043 Marburg, Germany; 2) Institute for The Distribution of the JAK/STAT Ligand Unpaired (Upd) During Biochemistry, Justus-Liebig-Universität, 35392 Gieen, Germany. Oogenesis. Dustin W. Perry, Travis R. Sexton, Douglas A. Harrison. Dept Biology, University of Kentucky, Lexington, KY. 204C Sbf pseudophosphatase coregulates PI(3)P homeostasis and Rab21 215B activity in endocytic control of dynamic hemocyte shape. Steve Jean, The effect of Upd3 on stem cells in Drosophila testes. Lingfeng Tang, Sarah Cox, Amy Kiger. Division of Biological Sciences, University of Douglas Harrison. Department of Biology, University of Kentucky, California San Diego, San Diego, CA. Lexington, KY.

205A 216C Identification of nuclear localization mechanisms of the cell polarity Sequoia affects leading cell migratory behaviour in Drosophila trachea regulator Bazooka. Michael P. Krahn, Andreas Wodarz. Department by regulating FGF levels. Sofia J. Araujo, Jordi Casanova. IBMB- of Stem Cell Biology, University of Goettingen, Germany. CSIC, IRB Barcelona, C/ Baldiri Reixac, Barcelona, Spain.

206B 217A AP-1 controls trafficking of Notch and Sanpodo towards an E-Cadherin Cytoskeletal polarization during collective cell migration in the junctional domain to regulate cell fate specification of sensory organ Drosophila egg chamber. Maureen P. Cetera, Sally Horne-Badovinac. precursors. Roland Le Borgne, Nicolas Loyer, Najate Benhra, DRSB, University of Chicago, Chicago, IL. Mathieu Cotton. Developmental Cell Biology, CNRS UMR 6061- Institut de Genetique et Developpement de Rennes, Rennes, France. 218B Par-1 regulates the spatial activity of myosin in migrating border cells. 207C Pralay Majumder, George Aranjuez, Jocelyn McDonald. Department Dlg5 regulates border cell migration and follicle epithelium of Molecular Genetics, Lerner Research Institute, Cleveland Clinic, development during Drosophila oogenesis. Jun Luo, Jiong Chen. Cleveland, OH. Model Animal Research Center, Nanjing University, Nanjing, China. 219C 208A Molecular Changes that Enable Cell Rearrangement and Detachment Quantitative Analysis of Capicua Nucleocytoplasmic Shuttling in the from the Ovarian Epithelium. Lathiena Manning, Alvin Kennedy, Drosophila Embryo. Victoria M. Sanchez1, Yoosik Kim1, Oliver Michelle Starz-Gaiano. Dept. of Biological Sciences, UMBC, Grimm2, Eric F. Wieschaus2, Stanislav Y. Shvartsman1,2. 1) Baltimore MD. Chemical and Biological Engineering, Princeton University, Princeton, NJ; 2) Molecular Biology, Princeton University, Princeton, NJ. 220A In vivo regulation of cell migration by the recycling endosome. Damien Ramel, Gloria Assaker, Gregory Emery. Institute for Research in Immunology and Cancer, Montreal, Quebec, Canada.

POSTER SESSIONS See page 16 for presentation schedule Poster board number is in bold above title. The first author is the presenter. Full abstracts can be found online at drosophila-conf.org

221B 229A Role of Drosophila Wash in cell migration. Evelyn Rodriguez-Mesa, An in vivo RNAi Screen for Identification of Genes Involved in Follicle- Susan M. Parkhurst. Fred Hutchinson Cancer Research Center, Seattle, Cell Differentiation and Cell-Cycle Switches. Dongyu Jia, Yi-Chun WA. Huang, Wu-Min Deng. Department of Biological Science, Florida State University, Tallahassee, FL. 222C A putative neurotransmitter transporter bloated tubules (blot) is required 230B for Drosophila Border cell migration. Ping Wan, Jiong Chen. Model Modulation of Notch Signaling by the Drosophila Xylosyltransferase Animal Research Center, Nanjing University, Nanjing, China. Shams. Tom Lee1, Maya Sethi2, Jessica Leonardi1,3, Hans Bakker2, Hamed Jafar-Nejad1,3. 1) Institute of Molecular Medicine, University 223A of Texas Health Science Center, Houston, TX; 2) Hannover Medical Enzymatic activity-independent functions of O-fucosyltransferase 1 in School, Hannover, Germany; 3) Program in Developmental Biology, the folding and trafficking of the Notch receptor in Drosophila. Naoki Baylor College of Medicine, Houston, TX. Aoyama1, Tomonori Ayukawa1,2, Akira Ishio1, Takuya Suzuki1,2, Kenjiroo Matsumoto1,2, Takeshi Sasamura1, Tetsuya Okajima3, 231C Kenji Matsuno1,2. 1) Dept. Biol. Sci. & Tech., Tokyo Univ Scinece, Epsin functions as an atypical clathrin adapter in Notch signaling. Noda, Chiba, Japan; 2) G & DRC., Tokyo Univ Science, Noda, Chiba, Xuanhua Xie, Janice Fischer. Dept MCDB, Univ Texas, Austin, Japan; 3) Nagoya University Graduate School of Bioagricultural Austin, TX. Sciences, Department of Applied Molecular Biosciences, Japan. 232A 224B The EJC Acts on RAS1/MAPK Signaling by Altering the Splicing of Tempura, a putative protein prenyltransferase subunit, is a novel Notch mapk/rl. Dariel Ashton-Beaucage, Christian Udel, Hugo Lavoie, signaling regulator. Wu-Lin Charng1,6, Shinya Yamamoto1,6, Manish Caroline Baril, Martin Lefrançois, Anne-Sophie Guenier, Jean Jaiswal2, Vafa Bayat1,3, Bo Xiong1, Ke Zhang4, Hector Sandoval2, Duchaine, Daniel Lamarre, Patrick Gendron, Sébastien Lemieux, Gabriela David1, Hsiang-Chih Lu1, Adeel Jawaid2, Hugo Bellen1,2,5. Marc Therrien. IRIC, Univ de Montreal, Montreal, PQ, Canada. 1) Program in Developmental Biology; 2) Department of Molecular and Human Genetics; 3) Medical Scientist Training Program; 4) Structural 233B and Computational Biology & Molecular Biophysics Program; 5) Evidence for monomeric -catenin as a component of cadherin catenin Howard Hughes Medical Institute, Baylor College of Medicine, complex. Ridhdhi Desai1, Milena Pellikka1, Noboru Ishiyama2, Ritu Houston, Texas; 6) Equal contribution. Sarpal1, Mitsuhiko Ikura2, Ulrich Tepass1. 1) Cell & Systems Biol, University of Toronto, ON, Canada; 2) Division of Signaling Biology, 225C ON, Canada. Specific Extracellular EGF-like repeats within Serrate form a Notch Inhibitory Region. Robert J. Fleming1, Katzuya Horu2, Anindya Sen2. 234C 1) Biol Dept, Trinity Col, Hartford, CT; 2) Department of Cell Biology, A genome-wide RNAi screen to identify novel pathways responding to Harvard Medical School, Boston, MA. Caffeine. Francesca Di Cara1, Brendon Parsons2, Ran Zhuo1, Edan Foley2, Kirst King-Jones1. 1) Biological Science, University of Alberta, 226A Edmonton, Alberta, Canada; 2) MMI Dept, University of Alberta, dEHBP1 affects Notch signaling by impairing Delta trafficking during Edmonton, Alberta, Canada. asymmetric divisions. Nikos Giagtzoglou1, Shinya Yamamoto2, Diana Zitserman5, Hillary Groves2, Hayley Klein3, Karen Schulze1, Hao 235A Wang3, Fabrice Roegiers5, Hugo Bellen1,2,3,4. 1) Howard Hughes The sumoylation pathway regulates JNK pathway through the action of Medical Institute, Baylor College of Medicine, Houston, TX. 77030; 2) Hipk. Renjie Jiao1, Hai Huang1,2, Hanqing Chen1,2, Xuehong Liang1, Program in Developmental Biology, Baylor College of Medicine, Changqing Li1, Lei Xue3, Jun Ma4. 1) Institute of Biophysics, Chinese Houston, TX. 77030; 3) Department of Molecular and Human Genetics, Academy of Sciences, Beijing, Beijing, China; 2) Graduate School of Baylor College of Medicine, Houston, TX. 77030; 4) Department of the Chinese Academy of Sciences, Beijing, China; 3) Shanghai Key Neuroscience, Baylor College of Medicine, Houston, TX. 77030; 5) Fox Laboratory for Signaling and Diseases, School of Life Science and Chase Cancer Center, Philadelphia, PA 19111. Technology, Tongji University, Shanghai, China; 4) Divisions of Biomedical Informatics and Developmental Biology, Cincinnati 227B Children’s Research Foundation, Cincinnati, OH, USA. dEHBP1 regulates Notch mediated lateral inhibition in the Drosophila eye. Nikos Giagtzoglou1, Tongchao Li2, Hugo Bellen1,2,3,4. 1) Howard 236B Hughes Medical Institute, Baylor College of Medicine, Houston, TX; 2) Arrestins are required for activation of Drosophila Rh1 rhodopsin Program in Developmental Biology, Baylor College of Medicine, kinase. Alexander V. Kiselev, Joseph E. O'Tousa. Biological Sci, Houston, TX; 3) Department of Human and Molecular Genetics, Baylor Notre Dame Univ, Notre Dame, IN. College of Medicine, Houston, TX; 4) Department of Neuroscience, Baylor College of Medicine, Houston, TX. 237C Engrailed homeoprotein acts as a signaling molecule in the developing 228C fly. Sophie Layalle1, Michel Volovitch3, Bruno Mugat2, Nathalie Intracellular Notch activation is regulated by the core component of the Bonneaud1, Marie-Laure Parmentier1, Alain Prochiantz3, Alain ESCRT-III complex Shrub and by the ubiquitin ligase Deltex. Kazuya Joliot3, Florence Maschat1. 1) Institut de Génomique Fonctionnelle, Hori1, Anindya Sen1, Tom Kirchhausen1,2, Spyros Artavanis- Neurobiology Department, CNRS UMR5203 INSERM U661, Tsakonas1,3. 1) Dept Cell Biol, Harvard Med Sch, Boston, MA; 2) Montpellier, France; 2) Institut de Génétique Humaine, CNRS Immune Disease Institute, Harvard Med Sch, Boston, MA; 3) Collège de UPR1142, Montpellier, France; 3) Collège de France, Ecole normale France, Paris, France. supérieure. CNRS UMR 7233, Paris, France.

238A Forward Genetic Screening to Identify Genes in Cell Competition. Chang Hyun Lee, Gerard Rimesso, Nicholas Baker. Genetics, Albert Einstein College of Medicine, Bronx, NY.

POSTER SESSIONS See page 16 for presentation schedule Poster board number is in bold above title. The first author is the presenter. Full abstracts can be found online at drosophila-conf.org

239B 249C Separating planar cell polarity and Hippo pathway activities of the Investigating the function of a RhoGAP, Conundrum, that interacts with protocadherin Fat. Hitoshi Matakatsu, Seth Blair. Dept Zoology, Univ Moesin. Amanda L. Neisch, Richard G. Fehon. Dept MGCB, Univ Wisconsin, Madison, WI. Chicago, Chicago, IL.

240C 250A Egghead and Brainiac Regulate Chordotonal Organ Precursor AP-1 and clathrin are essential for secretory granule biogenesis in Recruitment. Stephanie M. Pontier1, Xue Li Guan2, François Drosophila. Jason Burgess1,2, Milu Jauregui1,2, Julie Tan1,2, Janet Schweisguth1. 1) Development, Institut Pasteur, Paris, France; 2) Swiss Rollins3, Henry Chang4, Sylvie Lallet5, Roland Le Borgne5, Helmut Tropical and Public Health, Institute, Basel, Switzerland. Krämer6, Julie Brill1,2. 1) Developmental and Stem Cell Biology, Hospital for SickKids, Toronto, ON, Canada; 2) Molecular Genetics, 241A University of Toronto, Toronto, ON, Canada; 3) Natural Sciences, acal is probably a non-coding RNA that negatively regulates Jun N- College of Mount Saint Vincent, Riverdale, NY, United States; 4) terminal Kinase (JNK) signaling during embryonic dorsal closure. Luis Biological Sciences, Purdue University, West Lafayette, IN, United Daniel Ríos-Barrera, Juan Rafael Riesgo-Escovar. Developmental States; 5) CNRS, Université de Rennes, Rennes, France; 6) Biology Dept., Neurobiology Institute, Universidad Nacional Autónoma Neuroscience, University of Texas Southwestern Medical Center, de México, Querétaro, Juriquilla, Mexico. Dallas, TX, United States.

242B 251B Identification and Functional Characterization of Novel Components of Investigating the Mechanisms of Wnt/Wg Secretion. Varun the Insulin/TOR Pathway in Drosophila melanogaster. Ralf B. Chaudhary, Julia Gross, Michael Boutros. Division Signaling and Schittenhelm1, Timo Glatter2, Oliver Rinner1, Matthias Gstaiger1, Functional Genomics, DKFZ Heidelberg and University of Heidelberg, Ruedi Aebersold1, Hugo Stocker1, Ernst Hafen1. 1) Institute of Germany. Molecular Systems Biology, ETH Zurich, Switzerland; 2) Proteomics Core Facility, Biocenter, University of Basel, Switzerland. 252C Cell death factors, tumor suppressors and cytoskeletal proteins control 243C prepupal activities of Drosophila salivary glands preceding ecdysone- The retinoblastoma protein RBF and the PHD zinc-finger domain triggered programmed histolysis. Robert Farkas1, Lucia Mentelova1,2, protein Rhinoceros coordinately regulate EGFR signaling and the Erika Halaszova1,2, Daniel Vlcek2, Milan Beno1, Alena Hercegova1,2, induction of photoreceptor differentiation. Madina Z. Sukhanova1, Peter Danis1,2, Ivan Raska3, Bernard Mechler3,4. 1) Inst Experimental Latishya J. Steele1,2, Wei Du1. 1) Ben May Dept Cancer Rest, Univ Endocrinology, Slovak Academy Sciences, Bratislava, Slovakia; 2) Chicago, Chicago, IL; 2) Department of Cell Biology, Harvard Medical Department of Genetics, Faculty of Science, Comenius University, School, Boston, MA. Bratislava, Slovakia; 3) Institute of Cellular Biology and Pathology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic; 4) 244A Department of Developmental Genetics, Deutsches Ligand Specificity in EGFR Signaling. Christina L. Austin, Amanda Krebsforschungszentrum-ZMBH Allianz, Heidelberg, Germany. Simcox. Molecular Genetics, The Ohio State University, Columbus, OH. 253A Wg regulation by the cytokinesis proteins, Tum and PavWingless/Wnt. 245B Elisabeth Greer, Anna Chao, Amy Bejsovec. Biology, Duke Characterization of novel epidermal growth factor receptor targets with University, Durham, NC. apparent roles in Drosophila egg and wing development. Lisa A. Kadlec, Jacquelyn Gallo, Dawn Gregor, Hannah Laimer, David 254B Marr. Dept of Biology, Wilkes University, Wilkes-Barre, PA. Examination of cell autonomous and non-autonomous effects of APC loss in the developing Drosophila wing. Kellie Kravarik, Sandra 246C Zimmerman, Amy Fuller, Brooke McCartney. Department of -arrestin Kurtz inhibits MAPK and Toll signaling in Drosophila Biological Sciences, Carnegie Mellon University, Pittsburgh, PA. development. Alexey Veraksa1, Marla Tipping1, Yoosik Kim2, Stanislav Y. Shvartsman2. 1) Department of Biology, University of 255C Massachusetts Boston, Boston, MA; 2) Department of Chemical Testing interactions between the central repeats of APC2 and Armadillo Engineering and Lewis-Sigler Institute for Integrative Genomics, in Wnt signal transduction. Ezgi Kunttas Tatli, Mengning Zhou, Princeton University, Princeton, NJ. Sophie Zhouzheng, Krista Carter, Megha Kapur, Alys Cheatle, Richard Decal, Brooke McCartney. Biological Sciences, Carnegie 247A Mellon University, Pittsburgh, PA. RTK/Ras/MAPK signaling in the visceral mesoderm does not require Pnt as a transcriptional effector to specify founder cell fate. Yiyun 256A Zhou1,2, Marc S. Halfon1,2. 1) Dept Biochem, SUNY at Buffalo, A comprehensive screen for micro-RNA (miR) modulators of the Buffalo, NY; 2) NYS Center of Excellence in Bioinformatics & Life Wnt/Wg pathway. Raluca Pancratov1, Felix Peng1, Jr-Shiuan Yang2, Sciences. Eric Lai2, Ramanuj DasGupta1. 1) Cancer Inst., New York Univ Sch Med, New York, NY; 2) Sloan Kettering Inst., New York, NY. 248B New Connections: The guanine nucelotide exchange factor, GEFmeso, 257B interacts with multiple GTPases to regulate embryonic development and Testing a Paracrine Signaling Role for Wg in Drosophila Ostia imaginal disc morphogenesis. Ashley M. Iketani, Tangi Smallwood, Formation. Gloriana Trujillo, Candice Lovato, Jill Hendren, Lynda Samuel Fox, Christopher Bailey, Laurence von Kalm. Biology, Helander, Richard Cripps. Department of Biology, University of New University of Central Florida, Orlando, FL. Mexico, Albuquerque, NM, USA 87131.

POSTER SESSIONS See page 16 for presentation schedule Poster board number is in bold above title. The first author is the presenter. Full abstracts can be found online at drosophila-conf.org

270C Cell Cycle and Checkpoints CycA controls endoreplication dynamics in the Drosophila bristle cell lineage. Jérémy Sallé, Michel Gho, Agnès Audibert. UMR 7622, 258C Developmental Biology Laboratory, CNRS-University Paris VI. 9, Quai Investigating the function and cell cycle regulation of an uncharacterized Saint Bernard, 75005 Paris, France. microtubule-associated protein (MAP). Sarah G. Hainline, Laura A. Lee. Cell and Developmental Biology, Vanderbilt University, Nashville, 271A TN. Deficiency screens reveal Pineapple eye, a predicted E3 ubiquitin- conjugating enzyme, as an essential regulator of Drosophila germline 259A stem cell self-renewal. Yalan Xing, Irina Kurtz, Jillian Legard, In Vivo and in vitro analysis of the interaction between Psf2 and Chk2 in Manisha Thuparani, Timothy Dosey, Hannele Ruohola-Baker. D. melanogaster. Jeffrey P. Chmielewski, Laura Henderson, Tim W. Department of Biochemistry, ISCRM, University of Washington, Seattle Christensen. Biology, East Carolina University, Greenville, NC. WA.

260B 272B An RNAi screen for regulators of the G2/M DNA damage checkpoint. The Regulation and Assembly of Histone Locus Bodies. Esteban Terzo, Shu Kondo, Norbert Perrimon. Gen, Harvard Med Sch, Boston, MA. Anne White, Brandon Burch, Xiao-cui Yang, Pamela Gasdaska, Zbigniew Dominski, William Marzluff, Robert Duronio. University 261C of North Carolina, Chapel Hill, NC. Developmental analysis and tissue specificity of checkpoint genes in Drosophila melanogaster. Sara Morais da Silva1, Nicolas Malmanche2, Claudio Sunkel1. 1) Molecular Genetics, IBMC, Porto, Cell Death Portugal; 2) Stowers Institute for Medical Research, Kansas City, USA. 273C 262A Autophagy in Drosophila ovaries is induced by starvation and is The oocyte-specific function of dPds5 in insulator body assembly is required for oogenesis. Julia M. I. Barth1, Janos Szabad2, Ernst monitored by a new meiotic checkpoint. Raquel A. M. Santos, Patricia Hafen1, Katja Köhler1. 1) Department of Biology, Institute of Silva, Vitor Barbosa. Instituto Gulbenkian de Ciência (IGC), Rua da Molecular Systems Biology, ETH Zurich, Zurich, Switzerland; 2) Quinta Grande, 6, 2780-156 Oeiras, Portugal. Departement of Biology, Faculty of Medicine, University of Szeged, Szeged, Hungary. 263B Studying the dynamics of Rbf/dE2F transcriptional regulation in the 274A Drosophila midgut by tissue-specific ChIP-Seq. Jerome P. Korzelius, Gradients of a Ubiquitin E3 Ligase Inhibitor and a Caspase Inhibitor Bruce A. Edgar. DKFZ/ZMBH Alliance, Heidelberg, Germany. Determine Differentiation or Death in Spermatids. Eli Arama, Yosef Kaplan, Liron Gibbs-Bar, Yossi Kalifa, Yael Feinstein-Rotkopf. 264C Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel. Cell cycle regulation by Cul4Cdt2 in the early Drosophila embryo. Christina I. Swanson1,2, Robert J. Duronio1. 1) Department of 275B Biology, University of North Carolina, Chapel Hill, NC; 2) The SPIRE The role of apoptosis and JNK signaling in dpp-mediated ventral head Program, University of North Carolina, Chapel Hill, NC. development. Sung-Yeon Park, Brian Stultz, Deborah Hursh. Division of Cell and Gene Therapy, Center for Biologics Evaluation and 265A Research, FDA, Bethesda, MD20892. Drosophila DNA ligase 3 is an essential gene involved in DNA single- and double-strand break repair. Alice Witsell, Camille Petersen, Ilana 276C Traynis, Mitch McVey. Dept Biol, Tufts Univ, Medford, MA. Signaling Pathways Underlying Metabolic Control of Apoptosis in Drosophila. Chih-Sheng Yang1, Thomas Merritt2, Sally Kornbluth1,3. 266B 1) Molecular Cancer Biology Program, Duke University Medical The structural and functional analysis of the Orc6 protein. Igor N. Center, Durham, NC 27710 USA; 2) Dept of Chemistry and Chesnokov1, Maxim Balasov1, Shixuan Liu2, Hongfei Wang2, Lijie Biochemistry Laurentian University, Ontario P3E 2C6, Canada; 3) Dept Wu2, Yingfang Liu2. 1) Dept Biochem & Molec Gen, Univ Alabama, of Pharmacology and Cancer Biology, Duke University Medical Center, Birmingham, AL; 2) National Laboratory of Biological Durham, NC 27710, USA. Macromolecules, Institute of Biophysics, Beijing, China. 277A 267C The Companion of Reaper Gene is a Potent Inducer of Apoptosis. Investigating the mitotic to endocycle transition in D. melanogaster. Christian W. Antonio1, Zhou Lei2, Gina Chan2, Yanping Zhang2, Christiane A. Hassel, Brian R. Calvi. Department of Biology, Indiana Rong Yuan2, Bergmann Andreas1. 1) Biochem & Molec Biol, MD University, Bloomington, IN. Anderson Cancer Ctr, Houston, TX; 2) Department of Molecular Genetics and Microbiology, College of Medicine, University of Florida, 268A Gainesville, FL. Characterization of DNA Polymerase using a combined in vivo and in vitro strategy. Chad M. Hunter1, Lena M. Keller1, Bonnie J. Bolkan2, 278B Tim W. Christensen1. 1) Department of Biology, East Carolina The Drosophila receptor tyrosine kinase tie interacts with the microRNA University, Greenville, NC; 2) CROET, Oregon Hlth & Sci Univ, bantam to regulate organismal survival following exposure to ionizing Portland, OR. radiation. Amber E. Bilak, Tin Tin Su. Molec Cell & Dev Bio, Univ Colorado Boulder, Boulder, CO. 269B Identification and genetic-molecular analysis of new genes required for the control of cell proliferation and neural differentiation. Beatriz Perez San Juan, Baonza Antonio. Development biology, CBMSO, Madrid (Spain), Madrid, Spain.

POSTER SESSIONS See page 16 for presentation schedule Poster board number is in bold above title. The first author is the presenter. Full abstracts can be found online at drosophila-conf.org

279C 289A A Genetic Screen for Cell Death Regulators in Drosophila melanogaster Direct and indirect roles of the mitochondria in caspase activation during Oogenesis. Michelle Gammill1, Victoria Jenkins1, Tatevik Drosophila spermatogenesis. Liat Ravid, Eli Arama. Weizmann Keshishyan1, Jeremy Nguyen1, Jemma Taipan1, Sarah Durrin1, Luz institute of science, Rehovot, Israel. Ceballos1, Aileen Leung1, Ruth Ranum2, Rebecca Chen3, Elizabeth Tanner1, Jeanne Peterson1, Kim McCall1. 1) Department of Biology, 290B Boston University, Boston, MA; 2) Concordia College, Moorhead, MN; Genetic Screens To Isolate Regulators of Apoptosis-Induced 3) University of California Berkeley, Berkeley, CA. Compensatory Proliferation in Proliferating Drosophila Tissues. Shiuan Wang1,2, Yun Fan1, Andreas Bergmann1,2. 1) Biochemistry and 280A Molecular Biology, University of Texas M.D. Anderson Cancer Center, Bulsa, A Novel Regulator of Apoptosis During Metamorphosis. Yunsik Houston, TX; 2) Program in Developmental Biology, Baylor College of Kang2, Anne Sapiro2, Arash Bashirullah1. 1) Sch Pharmacy, Univ Medicine, One Baylor Plaza, Houston, TX. Wisconsin, Madison, Madison, WI; 2) Lab Genetics, Univ Wisconsin, Madison, Madison, WI. 291C Novel, caspase-independent, noncanonical cell death pathway in 281B Drosophila. Keren Yacobi-Sharon, Yuval Namdar, Eli Arama. Drosophila ASMase is required for apoptosis and photoreceptor Molecular Genetics, Weizmann Institute, Rehovot, Israel. homeostasis. Zhonghua Liu1, Zhiguo Ma1,2, Xun Huang1. 1) Institute of Genetics and Developmental Biology, Beijing, Beijing, China; 2) 292A Graduate School of Chinese Academy of Sciences, Beijing, China. How Do Endocycling Cells Block Apoptosis? Bingqing Zhang1, Sonam Mehrotra2, Jhomar E. Marquez3, Brian R. Calvi1. 1) Biology, 282C Indiana University, Bloomington, IN; 2) Department of Radiation Identification of novel regulators of apoptosis required during Oncology, CINJ-UMDNJ, New Brunswick, NJ; 3) Department of metamorphosis. Anne Sapiro, Sarah Ives, Yunsik Kang, Arash Biochemistry, Emory University School of Medicine, Atlanta, GA. Bashirullah. Pharmaceutical Sciences & Laboratory of Genetics, UW- Madison, Madison, WI. 293B Role of JAK/STAT signaling in Hid-mediated induction of apoptosis in 283A the Drosophila ovarian polar cell lineage. Antoine Borensztejn, Asma p53 and the JNK pathway establish a feedback loop to amplify the Khammari, Elisabeth Boissoneau, Anne-Marie Pret, François apoptotic response in Drosophila. Evgeny Shlevkov, Gines Morata. Agnès. CNRS - CGM, Gif-Sur-Yvette, France. Centro de Biología Molecular CSIC-UAM, Madrid, Spain. 294C 284B Basket and Draper regulate the engulfment of nurse cells by follicle cells Mechanism of radiation-induced p53-independent apoptosis in during starvation induced mid-oogenesis cell death. Allison Timmons1, Drosophila. Tin Tin Su1, Lyle Uyetake1, Petra van Bergeijk2. 1) MCD Jon Iker Etchegaray1, Tracy Pritchett1, Elaine Welch2, Kim Biology, University of Colorado, Boulder, CO 80309-0347; 2) McCall1. 1) Biology, Boston University, Boston, MA; 2) Albany State Rijksuniversiteit Groningen, Netherlands. University, Albany, GA.

285C 295A Cell type-specific control of apoptosis and cell survival in the Necrotic cell death is transcriptionally regulated in Drosophila. Kai Liu, developing Drosophila eye. Yun Fan, Andreas Bergmann. Dept Xinping Chen, Yuhong Li, Tao Wang, Lei Liu. School of Life Biochem & Molec Biol, UT MD Anderson Cancer Ctr, Houston, TX. Sciences, Peking University, Beijing, China.

286A 296B Tumor suppressor Caliban coordinates with p53 and E2F1 to regulate Coordinated expression of cell death genes regulates neuroblast DNA damage induced apoptosis and G1/S cell cycle transition. Xiaolin apoptosis. Ying Tan1, Megumu Yamada-Mabuchi1, Richa Arya1, Bi1, Yajie Wang1, Zhe Wang1, Qing Yuan2, Pingkun Zhou3, Qin Susan St. Pierre1,2, Wei Tang1,3, Marie Tosa1, Carrie Brachmann4, Wang2, Mark Mortin4, Deboroh Hursh5. 1) CAS Key Laboratory for Kristin White1. 1) CBRC, Massachusetts General Hospital/Harvard Biological Effects of Nanomaterials and Nanosafety, Chinese Academy Medical School, Building 149, 13th Street, Charlestown Massachusetts, of Sciences, Beijing,100049, China; 2) School of Life Sciences, 02129, U.S.A; 2) FlyBase, Harvard University, 16 Divinity Ave, Lanzhou University,Lanzhou, 730000, China; 3) Department of Cambridge, MA, 02138, USA; 3) The Forsyth Institute, Harvard School Radiation Toxicology and Oncology, Beijing Institute of Radiation of Dental Medicine, Boston, MA 02115, USA; 4) Department of Medicine, Beijing, 100850, China; 4) Laboratory of Molecular Genetics, Developmental and Cell Biology, University of California, Irvine, CA NICHD, NIH, Bethesda, MD, 20892, USA; 5) Division of Cellular and 92697, USA. Gene Therapies, CBER, FDA, Bethesda, MD, 20892, USA. 297C 287B Uncovering a novel cancer prevention mechanism in Drosophila Mapping the genes that involved in cell death in cell competition. through the analysis of a Hox responsive enhancer. Zongzhao Zhai1, Abhijit T. Kale, Nicholas E. Baker. Dept Genetics, Albert Einstein Col Nati Ha1, Daniela Bezdan2, Ingrid Lohmann1. 1) CellNetworks - Medicine, Bronx, NY. Cluster of Excellence and BIOQUANT Center, University of Heidelberg, D-69120 Heidelberg, Germany; 2) Max Planck Institute for 288C Developmental Biology, D-72076 Tübingen, Germany. Autophagy induced by mild ER stress protects against apoptosis in Drosophila photoreceptor cells. Clémence Levet, Antoine Fouillet, Marion Robin, Pierre Dourlen, Bertrand Mollereau. Laboratoire de Cell Division and Growth Control Biologie Moléculaire de la Cellule, Ecole Normale Supérieure de Lyon, Lyon, France. 298A Identifying novel genes controlling cell competition. Justin A. Bosch, Yassi Hafezi, Kevin Gandhi, Iswar Hariharan. Molecular and Cell Biology, University of California - Berkeley, Berkeley, CA.

POSTER SESSIONS See page 16 for presentation schedule Poster board number is in bold above title. The first author is the presenter. Full abstracts can be found online at drosophila-conf.org

299B 309C mahjong-Induced Cell Competition in Drosophila Follicular Epithelia. Differences in Astral vs Anastral Spindle Assembly Using Genetic and Yoichiro Tamori, Wu-Min Deng. Biological Science, Florida State Proteomic Approaches. Oscar A. Cabrera1, Violaine Mottier-Pavie2, University, Tallahassee, FL. Timothy L. Megraw1. 1) Biomedical Sciences, Florida State University College of Medicine, Tallahassee, FL; 2) Pharmacology, University of 300C Texas Southwestern Medical Center, Dallas, TX. Drosophila p53-related protein kinase (Dprpk) modulates bulk endocytosis and is required for PI3K/TOR pathway-dependent growth. 310A Alvaro Glavic1, Consuelo Ibar1, Constanza Vásquez1, Patricio A novel Centrosomin partner regulates spindle orientation and cell Olguín2. 1) Center for Genomics of the Cell, Faculty of Sciences, polarity in neural stem cells. Jieyan Chen. Biomedical Sciences, Florida Universidad de Chile, Santiago, Chile; 2) Department of Developmental State University, Tallahassee, FL. and Regenerative Biology, Mt. Sinai School of Medicine, New York, EEUU. 311B Design of new Drosophila acentriolar cell lines for studying mitosis in 301A absence of centrosome. Alain Debec1, Nicolas Lecland1, Nicolas Drosophila viriato/Nol12 is a dMyc target that regulates nucleolar Malmanche2, Sara Pereira2, Helder Maiato2, Antoine Guichet1. 1) architecture and is required for dMyc-stimulated cell growth. Joana IJM, UMR 7592, Paris, France; 2) CID lab, IBMC, Porto, Portugal. Marinho1,2, Fernando Casares1,3, Paulo S. Pereira1. 1) Instituto de Biologia Molecular e Celular (IBMC), Universidade do Porto, 4150-180 312C Porto, Portugal; 2) Ph.D. Programme in Experimental Biology and dOCRL controls PI(4,5)P2 homeostasis and is necessary for cleavage Biomedicine (PDBEB), Center for Neuroscience and Cell Biology, furrow stability during cytokinesis. Khaled Ben El Kadhi, Chantal University of Coimbra, 3004-517 Coimbra, Portugal; 3) Centro Andaluz Roubinet, Sara Solinet, Grégory Emery, Sébastien Carréno. IRIC - de Biología del Desarrollo (CABD), CSIC-JA-Universidad Pablo de University of Montreal, Montreal, Canada. Olavide, Ctra. de Utrera km1, Seville 41013, Spain. 313A 302B The role of Septins during asymmetric cell divisions of sensory organ Drosophila Brf is Essential for Cell and Organismal Growth and cells. Nabila Founounou, Roland Le Borgne. CNRS UMR 6061- Functions Downstream of Insulin/TOR Signaling. Lynne Marshall, IGDR Université de Rennes 1. Elizabeth J. Rideout, Savraj S. Grewal. Clark H. Smith Brain Tumour Centre, Southern Alberta Cancer Research Institute, and Department of 314B Biochemistry and Molecular Biology, University of Calgary, HRIC, Exploring the role for FoxO in body size regulation by the integration of 3330 Hospital Drive, Calgary, Alberta, T2N 4N1, Canada. insulin and ecdysone signaling. Takashi Koyama, Christen Mirth. Instituto Gulbenkian de Ciência, Oeiras, Portugal. 303C Developmental signalling pathways controlling dmyc transcription. 315C Leonie M. Quinn1, Amanda Lee1, Nicola Cranna1, Naomi Mitchell1, Homolog Coorientation at Metaphase Arrest in Female Meiosis. David Levens2. 1) Anatomy & Cell Biol, Univ Melbourne, Melbourne, William D. Gilliland, Shane Gillies, Khateriaa Pyrtel, Wonbeom Australia; 2) National Institute of Health, Bethesda, MD. Paik, Adrian Segura, Maria Uhler, Nneka Wallace. Department of Biological Sciences, DePaul University, Chicago, IL. 304A Characterization of l(2)37Cc, the Drosophila ortholog of Prohibitin1. 316A Stephanie Toering Peters. Biology Dept, Wartburg College, Waverly, Gamma-tubulin localizes to the anastral meiosis I spindle in Drosophila IA. oocytes. Stacie E. Hughes1, J. Scott Beeler1, Brian Slaughter1, Angela Seat1, R. Scott Hawley1,2. 1) Stowers Inst Med Res, Kansas City, MO; 305B 2) Department of Physiology, University of Kansas Medical Center, Ebi alleviates excess growth stimulation through its multiple functions Kansas City, Kansas, United States of America. against E2f in Drosophila. Leo Tsuda, Young-Mi Lim. Laboratory for Drug Discovery, National Center for Geriatrics and Gerontology, Obu- 317B City, Aichi, Japan. Calcineurin regulation by Sra/RCAN and a novel role of GSK-3 in completion of Drosophila female meiosis. Satomi Takeo, Selene 306C Swanson, Kavya Nandanan, Michael Washburn, Laurence Florens, Activation of Hippo controls Dronc levels to regulate caspase-mediated R. Scott Hawley. Stowers Inst Med Res, Kansas City, MO. apoptosis in Drosophila. Shlipi Verghese1, Mackenzie Sullivan2, Nanditha Ranganathan3, Amit Singh1,3,4, Madhuri Kango-Singh1,3,4. 318C 1) Department of Biology, University of Dayton, Dayton, OH; 2) Allied A role for Deco in meiotic cohesion rejuvenation and chiasma Health And Sports Science, University of Dayton, Dayton, OH; 3) Pre maintenance. Katherine A. Weng, Charlotte A. Jeffreys, Sharon E. Med Program, University of Dayton, Dayton, OH; 4) Center for Tissue Bickel. Department of Biological Sciences, Dartmouth College, Regeneration and Engineering at Dayton, University of Dayton, 300 Hanover, NH. College Park Dayton, OH 45469. 319A 307A Meiosis-Specific Control of the Anaphase Promoting Complex by Study the mechanism of growth control by HLH proteins, Daughterless Cortex. Zachary J. Whitfield, Terry L. Orr-Weaver. Whitehead and Extramacrochaetae. Lan-Hsin Wang, Nicholas Baker. Dept. of Institute and Dept. of Biology, Massachusetts Institute of Technology, Genetics, Albert Einstein College of Medicine, Bronx, NY. Cambridge, MA.

308B 320B Centrosomal protein complexes and their roles in centrosome SOLO associates with SMC1 in vivo and is required for various aspects biogenesis. Tomer Avidor-Reiss, Jayachandran Gopalakrishnan. of Drosophila female meiosis. Rihui Yan, Bruce McKee. Dept Dept Cell Biol, Harvard Medical Sch, Boston, MA. Biochem, Cell, Molec Biol, Univ Tennessee, Knoxville, TN.

POSTER SESSIONS See page 16 for presentation schedule Poster board number is in bold above title. The first author is the presenter. Full abstracts can be found online at drosophila-conf.org

321C 331A Dynamics of Moe activation creates a pattern of differential cortical Incorporating a model of chemical signalling factors into a cell-based stability to control cell division. Sébastien Carréno1, Barbara Decelle1, model of growing epithelial tissues. Ruth E. Baker1, Aaron Smith1, Gaetan Chicanne3, Bernard Payrastre3, François Payre2, Chantal David Kay3, Philip K. Maini1,2. 1) Centre for Mathematical Biology, Roubinet1,2. 1) IRIC - University of Montréal, Montréal, Canada; 2) Mathematical Institute, University of Oxford, 24-29 St Giles', Oxford, Université de Toulouse UPS, Centre de Biologie du Développement, OX1 3LB, UK; 2) Oxford Centre for Integrative Systems Biology, Toulouse, France; 3) Université de Toulouse UPS, Centre de University of Oxford, Department of Biochemistry, South Parks Road, Physiopathologie de Toulouse , France. Oxford, OX1 3QU, UK; 3) Oxford University Computing Laboratory, University of Oxford, Wolfson Building, Parks Road, Oxford, OX1 322A 3QD, UK. Stretched lagging chromosomes during anaphase increase spindle length and cell size. Shaila R. Kotadia1, Anne Royou2, William Sullivan1. 1) 332B University of California Santa Cruz, Santa Cruz, CA; 2) Institut Jacques Morphogenesis of the Drosophila pupal dorsal thorax epithelium. Floris Monod, Paris, France. Bosveld, Isabelle Bonnet, Boris Guirao, Francois Graner, Yohanns Bellaïche. Biologie du Développement, INSTITUT CURIE, Paris, 323B France. Drosophila aPKC is required for mitotic spindle orientation in larval wing disc epithelium. Rui G. Martinho1, Leonardo Guilgur1, Pedro 333C Prudencio1, Andre Rosa2, Tania Ferreira1, Ana Pimenta-Marques1, Homeodomain-interacting protein kinase inhibits Hippo signaling to Buzz Baum2, Rui G. Martinho1. 1) Instituto Gulbenkian de Ciencia, promote growth during Drosophila development. Joanna Chen, Esther Oeiras, Portugal; 2) MRC-Laboratory of Molecular Cell Biology, UCL, Verheyen. Molecular Biology and Biochemistry, Simon Fraser London, UK. University, Burnaby, British Columbia, Canada.

324C 334A Determining the molecular mechanisms of APC2’s cytoskeletal Actin-Capping Protein and the Hippo pathway regulate F-actin functions. John Poulton, Dave Roberts, Frank Mu, Mark Peifer. accumulation and tissue growth in Drosophila. Florence Janody, Dept. of Biology, University of North Carolina, Chapel Hill, NC. Beatriz García Fernández, Perdo Gaspar, Catarina Brás-Pereira, Barbara Jezowska, Sofia Raquel Rebelo. Actin Dynamics Unit, 325A Instituto Gulbenkian de Ciência, Oeiras - Lisbon, Portugal. Characterization of the novel growth-regulating gene lig. Roland Baumgartner1,2, Carmen Rottig1, Alexander Wepf1, Matthias 335B Gstaiger1, Hugo Stocker1, Ernst Hafen1. 1) ETHZ, Institute of Molecular and phenotypic characterization of fried mutants. Molecular Systems Biology (IMSB), Zürich, Switzerland; 2) Recipient Carlisdania Mendoza1, Alison Lindsay1, Gaurav Saharia2, Lillian of a DOC-fellowship of the Austrian Academy of Sciences at the Chiu1, Jason Morris1. 1) Department of Natural Sciences, Fordham Institute of Molecular Systems Biology. University, New York, NY; 2) Cognitive Science Program, McGill University, Montreal, Quebec, Canada. 326B A genetic screen to identify genes involved in imaginal disc 336C compensatory growth. Abigail R. Gerhold, Daniel Richter, Albert Yu, A gradient of the transcription factor Cut controls survival, proliferation Iswar Hariharan. Molecular and Cell Biology, University of and differentiation of Drosophila airway progenitors. Chrysoula California, Berkeley. Pitsouli1, Norbert Perrimon1,2. 1) Dept Gen, Harvard Med Sch, Boston, MA; 2) Howard Hughes Medical Institute. 327C Jabba mediates sequestration of histones on embryonic lipid droplets. 337A Zhihuan Li, Michael A. Welte. Department of Biology, University of Systemic coordination of organ growth in response to localized tissue Rochester, Rochester, NY. damage in Drosophila larvae. Alexander Shingleton, Nathan Parker. Department of Zoology, Michigan State University, East Lansing, MI. 328A Developmental Timing and Regulation of Size. Marisa M. Oliveira, 338B Christen K. Mirth. Instituto Gulbenkian de Ciência, Oeiras, Portugal. Investigating the putative function of Merlin in the nucleus. Cameron Berry, Amanda Neisch, Richard Fehon. Department of Molecular 329B Genetics and Cell Biology, University of Chicago, Chicago, IL. An in vivo screen for novel PLC- inhibitors. Justin R. Thackeray, Eric Britton, Katherine Driscoll, Craig Jeskey. Biology Department, 339C Clark University, Worcester, MA. Synergy between dE2F1 and Yki/Sd defines a distinct transcriptional program necessary to bypass cell cycle exit. Maxim Frolov1, Brandon 330C Nicolay1, Battuya Bayarmagnai1, Abul Islam2, Nuria Lopez-Bigas2. Identification and characterization of a mutant allele of DNApol-, 1) Biochem Molec Gen, Univ Illinois Chicago, Chicago, IL; 2) Research DNApol-pl10R, gene in Drosophila melanogaster. Akanksha Verma1, Unit on Biomedical Informatics, Department of Experimental and Sonali Sengupta2, Subhash Lakhotia1. 1) Zoology, Banaras Hindu Health Science, Universitat Pompeu Fabra, Barcelona, Spain. University,Varanasi, Uttar Pradesh, India; 2) School of Biosciences and Technology, Vellore Institute of Technology, Vellore, India. 340A Tumor induction in Drosophila by DNA minor groove binding ligands. Kirill I. Kirsanov, Ekaterina A. Lesovaya, Olga Yu. Susova, Gennadiy A. Belitsky, Marianna G. Yakubovskaya. Dept of Chemical Carcinogenesis, Blokhin CRC RAMS, Moscow, Russia.

POSTER SESSIONS See page 16 for presentation schedule Poster board number is in bold above title. The first author is the presenter. Full abstracts can be found online at drosophila-conf.org

341B 351C Zw3 phosphorylation of Mad restricts mitosis in the sensory organ Pendolino (Peo), a terminin-interacting protein required for Drosophila lineage during wing development. Stuart J. Newfeld, Janine Quijano, telomere protection. Giovanni Cenci1, Laura Ciapponi2, Grazia D. Michael Stinchfield. Sch Life Sci, Arizona State Univ, Tempe, AZ. Raffa2, Romina Burla2, Isabella Saggio2, Maurizio Gatti2. 1) Biol di Base ed Applicata, Universita dell'Aquila, L'Aquila, Italy; 2) Dept. 342C Biology and Biotechnology, Sapienza, University of Rome, Rome, Italy. Loss of PTEN confers growth advantage to imginal disc cells under starvation in Drosophila. Katarzyna Nowak, Gerhard Seisenbacher, 352A Hugo Stocker, Ernst Hafen. Institite of Molecular Systems Biology, Functional antagonism between histone H3K4 demethylases in vivo. ETH Zürich, Zürich, Hoenggerberg, Switzerland. Nicholas Dyson1, Luisa Di Stefano1,2, James Walker1, Giosalba Burgio3, Davide Corona3, Anders Näär1,4. 1) Massachusetts General Hospital Cancer Center, Harvard Medical School, Charlestown, MA, Chromatin and Epigenetics USA; 2) Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA, USA; 3) Istituto Telethon Dulbecco c/o 343A Universita' degli Studi di Palermo, Palermo, ITALY; 4) Department of A multidisciplinary approach to studies of HP1a-nucleosome interation. Cell Biology, Harvard Medical School, Boston, MA, USA. Diane E. Cryderman1, Abd Elhamid Azzaz2, Andrew S. Thomas1, Michael W. Vitalini1, Jason P. Price1, Adrian H. Elcock1, Michael A. 353B Shogren-Knaak2, Lori L. Wallrath1. 1) Biochemistry, Univ Iowa, Y chromosomal determinants and transmission of position effect Iowa City, IA; 2) Biochemistry, Biophysics and Molecular Biology, variegation. Keegan J. Kelsey, Elena Kwan, Andrew G. Clark. Iowa State University. Molecular Biology and Genetics, Cornell University, Ithaca, NY.

344B 354C Assembly and function of Drosophila melanogaster centromeric HP1a regulates the recognition of double strand breaks. James M. chromatin in meiosis and development. Elaine Dunleavy, Gary Mason, Raghuvar Dronamraju. Lab Molec Gen, D3-01, NIH/NIEHS, Karpen. Department of Genome Dynamics, Life Sciences Division, Res Triangle Park, NC. Lawrence Berkeley National Laboratory and Department of Molecular Cell Biology, UC Berkeley, Berkeley, CA. 355A A paternal imprint essential for the inheritance of telomere identity in 345C Drosophila. Yikang S. Rong, Guanjun Gao, Yan Cheng, Natalia Drosophila XNP/ATRX Increases Neuronal Apoptosis via the JNK and Wesolowska. NCI/NIH, Bethesda, MD. FOXO Pathway. Yoon Ki Hong, Soojin Hwang, Min Jung Lee, Soojin Lee, Darae Kim, Seung Hwan Park, Kyoung Sang Cho. 356B Department of Biological Sciences, Konkuk University, Seoul 143-701, Global nucleosome mobility during heat shock. Sheila Teves, Jorja Republic of Korea. Henikoff, Steven Henikoff. Fred Hutchinson Cancer Research Center, Seattle, WA. 346A Involvement of heterochromatin proteins in the transcriptional regulation 357C of the Drosophila sex determination masterswitch. Janel Rodriguez1, Regulation of Heterochromatin by the Histone Demethylase KDM4A. Hui Li2, Youngdong Yoo2, RamaKrishna Badugu2, Rebecca Serafin U. Colmenares, Joel Swenson, Cameron Kennedy, Sasha Kellum2, Jamila Horabin1. 1) Biomedical Sciences, Florida State Langley, Gary H. Karpen. Genome Dynamics, Lawrence Berkeley University, Tallahassee, FL; 2) Biology Department, University of National Lab, Berkeley, CA. Kentucky, Lexington, KY. 358A 347B Examining the role of 359-bp satellite DNA in ring-Y induced lethality Characterizing of Scaffold Attachment Factor A and its Dynamic Role in Drosophila melanogaster. Dagnie C. Howard, Patrick M. Ferree. in Nuclear Organization. John Aldrich, Keith Maggert. Department of Joint Science Dept. Claremont McKenna, Scripps, and Pitzer Colleges, Biology, Texas A&M University, College Station, TX. Claremont, CA.

348C 359B Comprehensive analysis of the Drosophila melanogaster chromatin Why are certain regions of the genome more susceptible to re- landscape differentiates among chromosomes, genes, and regulatory replication? Madhura Kadaba1, David M. MacAlpine2, Brian R. elements. Artyom A. Alekseyenko. Drosophila modENCODE Calvi1. 1) Department of Biology, Indiana University, Bloomington, IN; Chromatin Group. 2) Department of Pharmacology and Biology, Duke University Medical Center, Durham, NC. 349A Functional analysis of the CHD1 chromatin remodeling and assembly 360C factor. Jennifer A. Armstrong, Lakshmi V. Bugga, Liana Engie, Testing the Role of Topoisomerase II In Ring-Y Lethality. Hannah W. Janice Cho, Eugenie S. Hong, Kelsey Schmidt. Joint Science Kornfeld, Patrick M. Ferree. Joint Science Dept, Claremont McKenna, Department, Scripps, Pitzer and Claremont McKenna Colleges, Scripps and Pitzer Colleges, Claremont, CA 91711. Claremont, CA. 361A 350B Control of stem cell self-renewal by heterochromatin formation. Willis The role of suo/Top2 in the maitenance of chromosome structure and X. Li1,2, Yalan Xing1. 1) Dept Biomedical Genetics, Univ Rochester integrity. Silvia Bonaccorsi, Valentina Mengoli, Roberto Piergentili, Medical Ctr, Rochester, NY; 2) Dept of Medicine, Univ California, San Elisabetta Bucciarelli, Ramona Lattao, Maurizio Gatti. Dept Biology Diego, CA. and Biotechnology, Univ di Roma 'La Sapienza', Rome, Italy.

POSTER SESSIONS See page 16 for presentation schedule Poster board number is in bold above title. The first author is the presenter. Full abstracts can be found online at drosophila-conf.org

362B 373A CG7172 acts as a tumor suppressor by regulating heterochromatin. Su Functional interaction between the dSet1 and dTip60 complexes in Jun Lim, Pranabananda Dutta, Willis Li. University of Rochester chromatin regulation at promoters of transcribed genes. Thomas Kusch, Medical Center, Rochester, NY. Amanda Mei, Matthieu Caron. Molecular Biology and Biochemistry, Rutgers University, Piscataway, NJ. 363C Plasticity in patterns of histone modifications and chromosomal proteins 374B in Drosophila heterochromatin. Aki Minoda1, Drosophila Histone modification as a way to identify DNA elements critical for the modENCODE Chromatin Consortium2. 1) Dept Genome Dynamics, acquisition of drug tolerance. Xiaolei Li, Harish Krishnan, Ankur Lawrence Berkeley National Lab, Berkeley, CA; 2) Drosophila Abhishek, Nigel Atkinson. Sect Neurobiology, Univ Texas at Austin, modENCODE Chromatin Consortium. Austin, TX.

364A 375C Genetic analysis of SUUR protein interactions. Olga Posukh, Dmitry Assembly of Drosophila centromeric chromatin proteins during mitosis. Koryakov, Tatyana Kolesnikova, Igor Zhimulev. Department of Barbara Mellone1, Kathryn Grive1,2, Vladimir Shteyn3,5, Isaac Molecular and Cellular Biology, Inst. of Chemical Biology and Oderberg4,5, Gary Karpen5. 1) Molecular and Cell Biology, University Fundamental Medicine, Novosibirsk, Russian Federation. of Connecticut, Storrs, CT; 2) Brown University, Providence, RI; 3) Yale University, New Haven, CT; 4) MIT, Cambridge, MA; 5) 365B Lawrence Berkeley National Laboratory, Berkeley, CA. Drosophila Mcm10: One protein implicated in multiple cellular processes. Michael Reubens, Tim W. Christensen. East Carolina 376A University, Greenville, NC. Analysis of ATXN7 function in the SAGA chromatin modifying complex. Ryan D. Mohan, Vikki M. Weake, Lauren G. Shelton, 366C Laurence Florens, Michael P. Washburn, Susan M. Abmayr, Jerry Chromatin structure analysis of D. melanogaster chromosome 4. Nicole L. Workman. Stowers Institute for Medical Research, Kansas City, C. Riddle, Youngsook L. Jung, Tingting Gu, Artyom A. MO. Alekseyenko, Peter V. Kharchenko, Aki Minoda, Yuri B. Schwartz, Michael Y. Tolstorukov, Mitzi K. Kuroda, Vincenzo Pirrotta, Sarah 377B C. R. Elgin, Gary H. Karpen. modENCODE Drosophila Chromatin A genetic screen for mutations affecting the germline function of the Group. Suppressor of Hairy-wing insulator protein. Ryan M. Baxley1, Michael W. Klein2, Ashley B. Gaeth2, Joel A. Morales-Rosado2, Amber M. 367A Hohl3, Pamela K. Geyer1,2,3. 1) Molecular and Cellular Biology Gain of essential centromere function by the young HP1 gene Umbrea. Program, University of Iowa, Iowa City, IA; 2) Biochemistry Benjamin Ross1,2, Mary Alice Hiatt1, Danielle Vermaak1, Harmit Department, University of Iowa, Iowa City, IA; 3) Genetics Program, Malik1,2. 1) Basic Sciences Division, Fred Hutchinson Cancer Research University of Iowa, Iowa City, IA. Center, Seattle, WA; 2) Dept. of Molecular and Cellular Biology, University of Washington, Seattle, WA. 378C Insulator elements mediate long-range interactions between Polycomb 368B targets and between active enhancers in Drosophila. Hua-Bing Li, Testing interactions between the hybrid lethality genes Hmr and Lhr in Katsuhito Ohno, Vincenzo Pirrotta. Molecular Biology & D. melanogaster. Rajavasireddy P. Satyaki, Cuykendall Tawny, Biochemistry, Rutgers University, Piscataway, NJ. Kwak Hojoong, Ji Shuqing, Barbash Daniel. Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY. 379A A Novel Chromatin Barrier Element Delimits the Formation of 369C Facultative Heterochromatin Without Blocking Enhancer Function. The Role of Heterochromatin in the DNA Damage Response. Joel Nianwei Lin1, Keji Zhao2, Guangyao Li1, Lei Zhou1. 1) Molecular Swenson1,2, Irene Chiolo2, Serafin Colmenares2, Cameron Kennedy2, Genetics and Microbiology, University of Florida, Gainesville, FL; 2) Gary Karpen1,2. 1) Molec & Cell Biol, Univ California-Berkeley, Laboratory of Molecular Immunology, National Heart, Lung and Blood Berkeley, CA; 2) Genome Dynamics, Lawrence Berkeley National Institute, NIH, Bethesda, MD 20892. Laboratory, Berkeley, Ca. 380B 370A Pairing between gypsy insulator facilitates chromosomal Homolog pairing and sister chromatid cohesion in heterochromatin in rearrangements. Mikhail Savitsky, Oksana Kravchuk, Artem Drosophila male meiosis I. Jui-He Tsai, Rihui Yan, Bruce McKee. Tkachuk, Maria Kim. Institute of Gene Biology RAS, Moscow, Biochem, Cellular & Molec Biol, Univ Tennessee, Knoxville, TN. Russian Federation.

371B 381C Comparing the Effects of Invader4 with 1360 on Heterochromatin The broad role of CP190 protein in Drosophila chromatin insulator Targeting. Hao Yang, Monica Sentmanat, Sarah Elgin. Biology Dept, network. Yuri B. Schwartz, Daniela Linder-Basso, Peter V. Washington University in St. Louis, St. Louis , MO. Kharchenko, Michael Y. Tolstorukov, Maria Kim, Huabing Li, Andrey A. Gorchakov, Aki Minoda, Gregory Shanower, Artyom A. 372C Alekseyenko, Nicole C. Riddle, Cameron Kennedy, Sarah C. R. Acetylation of histone H4 by Chameau is required for proper expression Elgin, Mitzi I. Kuroda, Peter J. Park, Mikhail Savitsky, Gary H. of Notch target genes. Hai Huang1,2, Hanqing Chen1,2, Changqing Li1, Karpen, Vincenzo Pirrotta. Drosophila modENCODE Chromatin Qinghua Wu1,2, Xuehong Liang1, Renjie Jiao1. 1) State Key Group. Laboratory of Brain and Cognitive Science, Institute of Biophysics, the Chinese Academy of Sciences, Beijing, China; 2) Graduate School of the Chinese Academy of Sciences, Beijing, China.

POSTER SESSIONS See page 16 for presentation schedule Poster board number is in bold above title. The first author is the presenter. Full abstracts can be found online at drosophila-conf.org

382A 393C The epigenetics of TE control by small RNA in Drosophila virilis. Mutational analysis of Su(z)2 reveals both essential and regulatory Justin P. Blumenstiel1, Kim S. Box1, Jianwen Fang2, Christine residues. Son C. Nguyen1, Stephanie Yu2, Elaine Oberlick3, Chao- Yoder1, Daniel L. Brown1, Alex E. Abdullayev1. 1) Department of ting Wu1. 1) Department of Genetics, Harvard Medical School, Boston, Ecology and Evolutionary Biology, University of Kansas, Lawrence, MA; 2) Stanford University, Palo Alto, CA; 3) Emory University, KS; 2) Applied Bioinformatics Lab, University of Kansas, Lawrence, Atlanta, GA. KS. 394A 383B The Polyhomeotic Protein Induces Hyperplastic Tissue Overgrowth DNA methylation and DNA methyltransfearase in Drosophila Through the Activation of the JAK/STAT pathway. Rocio Simon1, melanogaster. Deepti D. Deobagkar, Chitra Panikar. Zoology, Inma Gonzalez2, Ana Busturia1. 1) CENTRO DE BIOLOGIA University of Pune, Pune, India. MOLECULAR "SEVERO OCHOA" (CSIC-UAM), MADRID, SPAIN; 2) INSTITUT DE GENETIQUE HUMAINE, CNRS, MONTPELLIER, 384C FRANCE. Identification of Genes Involved in Somatic Homolog Pairing. Eric Joyce, C.-Ting Wu. Genetics, Harvard Medical School, Boston, MA. 395B Genetic Analysis of Drosophila and Human BAP1 in Polycomb 385A Repression. Kim Younglan1, Shin Na-Ra2, Lee Sang-Wang2, Um Soo- Epigenetic protection of telomeres in the male germline. Benjamin Jong2, Chung Yun Doo1. 1) Department of Life Science, University of Loppin1, Raphaëlle Dubruille1, Lætitia Delabaere1, Gabriel Marais2, Seoul, Korea; 2) Dept. of Bioscience and Biotechnology, Sejong Guillermo Orsi1. 1) CGMC, CNRS UMR5534, University of Lyon, University, Korea. France; 2) LBBE, CNRS UMR5558, University of Lyon, France. 396C 386B The role and interactions of Drosophila SAF-B in transcriptional Role of histone acetylation in tissue-specific gene regulation at nuclear activity. Kudakwashe L. Kupara, Keith Maggert. Biology, Texas A lamina. Beatrice Milon, Haibo Cheng, Dmitry Nurminsky. and M University, College Station , TX. Biochemistry and Molecular Biology, University of Maryland Baltimore, Baltimore, MD. 397A Mining functional DNA elements in the Drosophila genome. Per 387C Stenberg, Philge Philip. Molecular Biology, Computational Life Mapping the Telomere elongation mutation in Drosophila. Hemakumar Science Cluster (CLiC), Umea University, Umea, Sweden. M. Reddy, James M. Mason. Laboratory of Molecular Genetics, NIH/NIEHS, Research Triangle Park, NC. Drosophila Models of Human 388A Characterization of genes required for cell-death induced inhibition of Diseases RNAi. Weiwu Xie, James Birchler. Biological Sci Div, Univ Missouri- Columbia, Columbia, MO. 398B A Drosophila Model of Fetal Alcohol Syndrome. Rachael L. French1, 389B Kimberly McClure2, Ulrike Heberlein2. 1) Biological Sciences, San De novo establishment of Polycomb-mediated repression. Jumana Jose State University, San Jose, CA; 2) Department of Anatomy, AlHaj Abed, Siddhi Desai, Judith Benes, Richard Jones. Southern University of California, San Francisco, 94158. Methodist University, Dallas, TX. 399C 390C Low-Dose Ethanol Treatment Impairs Learning in Drosophila Larvae. Polycomb group proteins connect distant genes within the nucleus. Brooks G. Robinson1, Sukant Khurana1, Jascha Pohl1, Wenke Li1, Frédéric Bantignies, Virginie Roure, Itys Comet, Benjamin Leblanc, Martin Hatch2, Amanda Cady2, Kristina Najjar2, Amar Bhat2, Ryan Bernd Schuettengruber, Giacomo Cavalli. Institut de Génétique Godinez2, Nigel Atkinson1,2. 1) Institute for Neuroscience, University Humaine, CNRS-UPR 1142, Montpellier, France. of Texas at Austin, Austin, TX; 2) Department of Neurobiology, University of Texas at Austin, Austin, TX. 391A Searching for the the location and function of TnaA, a trithorax group 400A protein which genetically interacts with Brahma. Juan Monribot, Lucia Developmental fate dictates cancer resistance in distinct tissue Gutiérrez, Zoraya Palomera, Rafael Juárez, Mario Zurita, Martha microenvironments of Drosophila epithelium. Sumbul J. Khan, Vázquez. Departamento de Genética del Desarrollo y Fisiología Mohammad Atif Alam, Sneh Harsh, Anjali Bajpayi, Ram Prakash Molecular del Instituto de Biotecnología de la Universidad Nacional Gupta, Ravikant Pandey, Arati Mishra, Pradip Sinha. Biological Autónoma de México. Av. Universidad #2001, Col. Chamilpa C.P. Sciences & Bioengineering Department, Indian Institute of Technology 62210 Cuernavaca, Morelos Apdo. Postal 510-3, C.P.62250. Kanpur, Kanpur208016, India.

392B 401B Do Polycomb and trithorax mutations affect reporter gene expression on The tumor suppressor parafibromin is a component of the Target of the 4th chromosome of Drosophila melanogaster? Perry Morocco, Rapamycin (TOR) signaling pathway. Erica M. Seigneur, Jianhua Sarah C. R. Elgin, Nicole C. Riddle. Biology Department, Washington Zhang, Leelama Panicker, William Simonds. Metabolic Diseases University in St. Louis, St. Louis, MO. Branch, National Institute of Diabetes, Digestive and Kidney Diseases, NIH, Bethesda, MD.

402C The Role of Cytochrome P450 Reductase and Oxidative Stress in a Heart Disease Model. Takeshi Akasaka, Karen Ocorr, Rolf Bodmer. Development and Aging Program, Sanford-Burnham Medical Research Institute, La Jolla, CA. 55

POSTER SESSIONS See page 16 for presentation schedule Poster board number is in bold above title. The first author is the presenter. Full abstracts can be found online at drosophila-conf.org

403A 414C Cardiac Disease in Wild Flies: Rare Alleles in Common Disease Loci? Cloning and Characterization of CG5315, a Drosophila Homolog of the Zhi Zhang1, Karen Ocorr1, Julie Brown2, Gregory Gibson2, Rolf Adiponectin Receptor. Su-Jin Kwak, Kyu-Sun Lee, Yoon Seok Seo, Bodmer1. 1) Center for Neuroscience and Aging, Sanford/Burnham Kweon Yu. Aging Research Center, KRIBB, Daejeon. Medical Research Institute, La Jolla, CA; 2) Center for Integrative Genomics,Geogia Institute of Technology,Atlanta, GA. 415A Fat Flies: Effects of a High Fat Diet in Drosophila. Erilynn Russo 404B Heinrichsen1, Gabriel G. Haddad1,2. 1) Department of Pediatrics, A Proteomic Screen for Dube3a targets. William J. Bodeen, Lawrence University of California, San Diego, La Jolla, CA; 2) Rady Children’s T. Reiter. Department of Neurology, University of Tennessee, Hospital, San Diego, CA. Memphis, TN. 416B 405C Nanoparticles in Drosophila: Organically Modified Silica nanoparticles Dube3a differentially regulates the number and amplitude of mEPSPs in are biocompatible and can be targeted to neurons in vivo. Shermali D. neuromuscular junction of third instar larvae. Rachel A. Chassan1,4, Gunawardena. Biological Sciences, The State University of New York, Reese Scroggs2,4, Lawrence Reiter2,3,4. 1) Rhodes College, Memphis, Buffalo, Buffalo, CA. TN; 2) Department of Anatomy and Neurobiology, UTHSC, Memphis, TN; 3) Department of Neurology, UTHSC, Memphis, TN; 4) 417C Neuroscience Institute, UTHSC, Memphis, TN. Mutations and Drugs that Increase Metabolism Can Suppress Seizures in the Bang-sensitive Paralytic Mutants. Daniel R. Kuebler, Leah 406A Kaercher, Bryan Stone. Dept Biology, Franciscan Univ, Steubenville, Genes nAchR-30D and Cam as modifiers of dystrophin gene function OH. in Drosophila melanogaster. Natalia Holub, Yulia Shalovylo, Olena Holub, Yaroslava Chernyk. Departament of Genetics and 418A Biotechnology, Ivan Franko National University, Lviv, Ukraine. Understanding the molecular targets and signaling mechanisms of novel inhibitors. Stefanie Stickel, Mara Stewart, Tin Tin Su. University of 407B Colorado at Boulder MCD Biology - Room A220 Campus Box 347 Transcriptional Regulation of Mef2 Expression in the Developing Boulder, CO 80309-0347. Mesoderm of Drosophila melanogaster. Carmelita Jaramillo1, Ginny Morris2, Richard Cripps3. 1) Department of Biology/MARC Program, 419B University of New Mexico, Albuquerque, NM; 2) Department of Characterization of anti-cancer compounds targeting polyamine import Biology/IMSD Program, University of New Mexico, Albuquerque, NM; into leg imaginal discs. Minpei Wang1,2, Otto Phanstiel IV2,3, 3) Department of Biology, University of New Mexico, Albuquerque, Laurence von Kalm1,2. 1) Department of Biology, University of Central NM. Florida, Orlando, FL; 2) Biomolecular Sciences Center, University of Central Florida, Orlando, FL; 3) Department of Medical Education, 408C College of Medicine, University of Central Florida, Orlando, FL. Drosophila tripartite-motif containing family member implicated in the normal stabilization of myofibrils. Elisa LaBeau1, Kenneth Bauman2, 420C Richard Cripps1, Erika Geisbrecht2. 1) Department of Biology, Mutations in AP-1 gamma are neurodegenerative in nature. Vafa University of New Mexico, Albuquerque, NM; 2) School of Biological Bayat1,2, Ke Zhang3, Manish Jaiswal4, Adeel Jawaid4, Bo Xiong1, Sciences, University of Missouri, Kansas City, MO. Hector Sandoval4, Michael Wangler4, Shinya Yamamoto1, Wu-Lin Charng1, Claire Haueter5, Gabriela David1, Hugo Bellen1,4,5. 1) 409A Developmental Biology Program, Baylor College of Medicine, One Isolation of Zasp-interacting proteins in Drosophila muscles. Kuo-An Baylor Plaza, Houston, TX 77030; 2) Medical Scientist Training Liao, Frieder Schöck. Department of Biology, McGill University, Program, Baylor College of Medicine, One Baylor Plaza, Houston, TX Montréal, Québec, Canada. 77030; 3) Structural and Computational Biology & Molecular Biophysics Graduate Program, Baylor College of Medicine, One Baylor 410B Plaza, Houston, TX 77030; 4) Department of Molecular and Human Dynamin in disease: a fly model of human centronuclear myopathy. Jen Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX K. Nguyen, Inês Ribeiro, Amy Kiger. Department of Biology, 77030; 5) Howard Hughes Medical Institute, Baylor College of University of California San Diego, La Jolla, CA. Medicine, One Baylor Plaza, Houston, TX 77030.

411C 421A Minocycline Allieviates Neural Circuit Defects in the Drosophila Fragile Microtubule Associated Proteins, Futsch and Tau are Required for X Model via a Tissue Inhibitor of Matrix Metalloproteinase-Dependent Development and Maintenance of the Drosophila Brain. Bonnie J. Pathway. Saul S. Siller, Kendal Broadie. Departments of Biological Bolkan, Doris Kretzschmar. CROET, Oregon Hlth & Sci Univ, Sciences and Cell and Developmental Biology, Kennedy Center for Portland, OR. Research on Human Development, Vanderbilt University, Nashville, TN 37232 USA. 422B Exportin-1 modulates polyglutamine toxicity. Ho Y. E. Chan1, H. 412A Tsoi1, W. M. Chan1, C. C. Wu1, C. H. Wong2, T. C. Cheng1, H. Y. Modulation of high fat diet induced heart dysfunction in Drosophila by Li2, K. F. Lau1, N. Perrimon3, P. C. Shaw1. 1) School of Life Sciences, the insulin/TOR pathway. Ryan T. Birse, Joan Choi, Kathryn Chinese Univ HK, Shatin, Hong Kong; 2) School of Biological Reardon, Jessica Rodriguez, Suzanne Graham, Soda Diop, Karen Sciences, Nanyang Technological University, Singapore; 3) Department Ocorr, Rolf Bodmer, Sean Oldham. Sanford. of Genetics, Harvard Medical School, USA.

413B 423C Obesity Is Linked To Insulin Signaling Through spargel, a PGC-1 The role of Superoxide Dismutase 2 in a Drosophila model of Machado- homologue in Drosophila. Claudette P. Davis, Subhas Mukherjee, Joseph Disease. Natalie M. Clark, John M. Warrick. Department of Atanu Duttaroy. Biol Department, Howard Univ, Washington, DC. Biology, University of Richmond, Richmond, VA.

POSTER SESSIONS See page 16 for presentation schedule Poster board number is in bold above title. The first author is the presenter. Full abstracts can be found online at drosophila-conf.org

424A 435C The neurodegenerative loe mutant interferes with the RHO pathway. The role of calcineurin in a Drosophila model of Alzheimer's Disease. Mandy Cook, Jill Wentzell, Doris Kretzschmar. CROET, Oregon Brie Paddock, Sean Miller, Marianna Vinokur, Suruchi Utreja, Health and Science University, Portland, OR. Aleister Saunders, Daniel Marenda. Biology, Drexel University, Philadelphia, PA. 425B Integration of hypoxia and inflammatory responses in a Parkinson’s 436A disease model. Joseph G. Daigle1, Rami Ajjuri1, Arati Inamdar1,2, Discovery of novel modulators of PINK1 combining cell based RNAi Janis O'Donnell1. 1) Dept of Biological Sciences, University of screens and Drosophila models of Parkinson’s disease. Joe Pogson, Alabama, Tuscaloosa, AL; 2) Dept of Plant Biology and Pathology, Alexander Whitworth. Department of Biomedical Science, University Rutgers University, New Brunswick, NJ. of Sheffield, UK.

426C 437B The prion protein induces vacuolation of central synapses and Using Drosophila to Study Gene-Environment Interactions in mitochondrial pathology in muscle fibers. Pedro Fernandez-Funez1,2, Parkinson's Disease. Ciara A. Remillard, Hakeem O. Lawal, Logan Diego Rincon-Limas1. 1) Dept Neurology, Univ Florida, Gainesville, Roberts, David E. Krantz. Department of Psychiatry and FL; 2) Dept Neuroscience, Univ Florida, Gainesville, FL. Biobehavioral Sciences, UCLA, Los Angeles, CA.

427A 438C Role of TATA-box Binding Protein (TBP) in PolyQ Mediated Circadian Rhythm and SODs in a Drosophila Model of MJD. Steven M. Neurodegenerative Diseases: Implication of Transcription Dysfunction. Richards, John Warrick. Biology, University of Richmond, VA. Tun-Chieh Hsu, Chun-Yen Yang, Ming-Tsan Su. Department of Life Science,National Taiwan Normal University, Taipei, Taiwan. 439A The PrP-N158D substitution confers conformational stability and 428B prevents prion disease. Jonatan Sanchez-Garcia1, Kurt Jensen1, Yan Drosophila melanogaster as a model to study the mechanism of action Zhang1, Joaquin Castilla3, Pedro Fernandez-Funez1,2, Diego Rincon- of fungal volatile organic compounds. Arati A. Inamdar, Joan W. Limas1. 1) Department of Neurology, UF, Gainesville, FL; 2) Bennett. Department of Plant Biology and Pathology, Rutgers, The Department of Neuroscience, UF, Gainesville, FL; 3) CIC bioGUNE, State University of New Jersey, New Brunswick, NJ. Derio, Bizkaia.

429C 440B Mechanisms of Prion Protein Misfolding. Kurt Jensen1, Jonatan Genetic analysis of a Drosophila IBMPFD model reveals a strong Sanchez-Garcia1, Yan Zhang1, Diego Rincon-Limas1, Pedro correlation between energy consumption and disease pathogenesis. Tzu- Fernandez-Funez1,2. 1) Dept. of Neurology, University of Florida, Kang Sang, Ya-Chu Chang, Wan-Tzu Hung, Yun-Chin Chang. Gainesville, FL; 2) Dept. of Neurosciences, University of Florida, Institute of Biotechnology, National Tsing Hua University Hsinchu, Gainesville, FL. Taiwan.

430A 441C A deficiency screen to identify rescuers of the Drosophila Adar null Genetic Manipulation of CREB Binding Protein Expression and its Role neural degeneration. Xianghua Li1, Simona Paro1, Leeanne McGurk2, in the Human Brain Degenerative Disease Spinocerebellar Ataxia-3 / Liam Keegan1, Mary O'Connell1. 1) MRC Human Genetics Unit, Machado Joseph Disease in the Fly Eye. Andrew L. Simmelink, John Edinburgh, United Kingdom; 2) University of Pennsylvania, M. Warrick. Department of Biology, University of richmond, Philadelphia, PA. Richmond, VA.

431B 442A Molecular study of age-related sensorineural hearing loss using CREB Binding Protein localization in a fly model of a human Drosophila. Young-Mi Lim, Leo Tsuda. Laboratory for Drug polyglutamine disease. Brian J. Sorace, Kristen Qutub, John M. Discovery, National Center for Geriatrics and Gerontology, Obu-City, Warrick. Department of Biology, University of Richmond, Richmond, Aichi, Japan. VA.

432C 443B Mutation in E1/Uba1 dramatically reduces lifespan and results in motor In vitro detection of neuroteratogen using Drosophila Melanogaster. impairment: a candidate Drosophila model for X-linked Infantile Spinal Nicole R. Sparks. Biology Dept, CSUSB, San Bernardino, CA. Muscular Atrophy. Hsiu-Yu Liu, Cathie Pfleger. Oncological Sciences, Mount Sinai School of Medicine, New York, NY. 444C Dysfunction of TBP dependent transcription may contribute to the 433A pathogenesis of tauopathy. Hsiang-Yu Wang. life science, national Development and Validation of a Late Stage Onset Alzheimer's Disease taiwan normal university, Taipei, Taiwan, Taiwan. model in Drosophila melanogaster. Siddhita Mhatre1, Sarah Michelson1, Radha Delvadia1, Daniel R. Marenda1,2. 1) Dept. of 445A Biology, Drexel University, Philadelphia, PA; 2) Dept. of Neurobiology Defects in Peroxisomal Biogenesis Lead to Age-Dependent Locomotor and Anatomy, Drexel University College of Medicine, Philadelphia, PA. Deficits and Retinal Dysfunction in Drosophila. Michael Wangler1, Vafa Bayat2,3, Nikolaos Giagtzoglou4, Claire Haueter4, Hugo Bellen4. 434B 1) Department of Molecular and Human Genetics, Baylor College of Secreted APP and APPL ectodomains are neuroprotective in a Medicine, Houston, TX; 2) Developmental Biology Program, Baylor Drosophila model of progressive neurodegeneration. Derek Musashe1, College of Medicine; 3) Medical Scientist Training Program, Baylor Katia Carmine-Simmen1,2, Doris Kretzschmar1. 1) Center for College of Medicine; 4) Howard Hughes Medical Institute, Baylor Research on Occupational and Environmental Toxicology, Oregon College of Medicine. Health & Science University, Portland, OR; 2) Department of Biochemistry, University of Alberta, Edmonton, Canada.

POSTER SESSIONS See page 16 for presentation schedule Poster board number is in bold above title. The first author is the presenter. Full abstracts can be found online at drosophila-conf.org

446B 456C Sicily, a mitochondrial protein, is implicated in neurodegeneration. Ke ATP7 is involved in MAPK signaling pathway during Drosophilia Zhang1, Manish Jaiswal2, Zhihong Li2, Vafa Bayat3, Hector development. Oky Maeng, Dahye Lee, Young-Ha Lee, Guang-Ho Sandoval2, Bo Xiong3, Shinya Yamamoto3, Wu-lin Charng3, Claire Cha. Infection Biology, College of Medicine, Chungnam National Haueter4, Gabriela David3, Adeel Jawaid2, Hugo Bellen1,2,3,4,5. 1) University, Daejeon, Korea. SCBMB Program, BAYLOR COLLEGE OF MEDICINE, HOUSTON, TX; 2) MOLECULAR & HUMAN GENETICS, BAYLOR COLLEGE 457A OF MEDICINE, HOUSTON, TX; 3) Program in Developmental Flies and human disease: Resources at the Bloomington Drosophila Biology, BAYLOR COLLEGE OF MEDICINE, HOUSTON, TX; 4) Stock Center for human disease-related research. Annette L. Parks, HHMI; 5) Neuroscience Department, Baylor College of Medicine, Kevin R. Cook, Kathy A. Matthews. Bloomington Drosophila Stock Houston, TX. Center, Dept. of Biology, Indiana University, Bloomington, IN.

447C 458B The aneuploidogen colchicine interfere the reproductive performance in Impact of disease-causing missense mutations in the extracellular Drosophila. Muñoz-Hernández Adriana, Ramos-Morales Patricia. domain of Crumbs on photoreceptor development in Drosophila. Milena Universidad Nacional Autónoma de México, Dept. Biología Celular, Pellikka, Ulrich Tepass. Dept.of Cell & Systems Biology, University of Lab. Genética y Toxicología Ambiental. Ciudad Universitaria 3000, Col. Toronto, Toronto, ON, Canada. Copilco Universidad, México, D.F. 459C 448A The effects of dietary modulation on bang-sensitive mutants, a fly model Distinct Mechanisms Underlying Tolerance to Intermittent and Constant of epilepsy. Elaine R. Reynolds, Stephen Conway, Alissa Coffey. Hypoxia in Drosophila melanogaster: Role of Hsp70 in Constant Neuroscience Program, Lafayette Col, Easton, PA. hypoxia. Priti Azad, Gabriel Haddad. Dept Pediatrics, Univ California, San Diego, La Jolla, CA. 460A Establishing Drosophila as a model to study human lamin processing. 449B Sandra R. Schulze1, Katie Adolphsen1, Sara Kevorkian1, Emily A deficiency-based screen for dominant modifiers of slamdance bang Matson1, Brian Kennedy2. 1) Dept Biol, Western Washington Univ, sensitivity. Derek M. Dean, Brian Shepherd, Dan Nachun. Biology, Bellingham, WA; 2) Department of Biochemistry University of Williams Col, Williamstown, MA. Washington Seattle, WA.

450C 461B Drosophila model to study stress hormone-like role of extracellular The E706K IBM3 muscle myosin mutation decreases the adenosine in vivo. Tomas Dolezal, Monika Zuberova, Milena chemomechanical properties and stability of the molecular motor. Novakova, Michaela Fenckova. Dept Molecular Biology, Faculty of Jennifer A. Suggs, Anthony Cammarato, Yang Wang, Anju Sciences, University of South Bohemia, Ceske Budejovice, Czech Melkani, Girish C. Melkani, William A. Kronert, Adam Republic. Bialobrodski, Sanford I. Bernstein. Dept Biol, San Diego State Univ

451A 462C Mito-Nuclear epistasis mapping implicates mitochondrial translation as Pharmacological Suppression of Excessive Repetitive Behavior in the source of disease states in Drosophila. Marissa A. Holmbeck, Eugenia Fly Model of Fragile-X Syndrome. John Tauber, Bing Zhang. Villa-Cuesta, Colin Meiklejohn, Kristi L. Montooth, David M. Department of Zoology, University of Oklahoma, Norman, OK. Rand. Brown University, Providence, RI. 463A 452B Mechanisms of Notch Signaling That Potentiate Survival During DIOPT, the DRSC Integrative Ortholog Prediction Tool. Claire Y. Hu1, Chronic Hypoxia. DeeAnn W. Visk1, Dan Zhou2, Gabriel H. Ian Flockhart1, Stephanie Mohr1, Norbert Perrimon1,2. 1) Drosophila Haddad2,3. 1) Division of Biological Sciences, University of California, RNAi Screening Center, Genetics Dept., Harvard Medical School, San Diego, La Jolla, CA; 2) Department of Pediatrics, School of Boston, MA; 2) Howard Hughes Medical Institute. Medicine, University of California, San Diego, La Jolla, CA; 3) Rady Children's Hospital, San Diego, CA. 453C Analysis of the functional relevance of the asthma susceptibility gene 464B ormdl3 using the model organism Drosophila melanogaster. Kimberley Eye pigmentation genes affect glycerol hypersensitivity in a Drosophila Kallsen1,2, Holger Heine1, Thomas Roeder2. 1) Research Center model for glycerol kinase deficiency. Patrick J. Wightman, Katrina Borstel, Parkallee 1-40, 23845 Borstel, Germany; 2) Institute of M. Dipple. Human Genetics, UCLA, Los Angeles, CA. Zoology, Department of Zoophysiology, Christian-Albrechts- Universität, Olshausenstrae 40, 24098 Kiel, Germany. 465C Role of antimicrobial peptide genes in hyperoxia. Huiwen Zhao1, Dan 454A Zhou1, Gabriel Haddad1,2,3. 1) Pediatrics Dept, UCSD, La Jolla, CA; 2) Stress Accelerates Muscular Dystrophy: A Genetic Analysis in Neuroscience Dept, UCSD, La Jolla, CA; 3) The Rady Children’s Drosophila. Mariya Kucherenko1, April Marrone1, Valentyna Hospital, San Diego, CA. Rishko1,2, Helena de Fatima Magliarelli1, Halyna Shcherbata1. 1) Gene expression and signaling, Max Planck Institute for biophysical chemistry, Goettingen, Germany; 2) Department of genetics and Evolution and Quantitative biotechnology, Ivan Franko National University of Lviv, Ukraine. Genetics 455B Drosophila Zasp mediates integrin activation. Jenny Long, Frieder 466A Schöck. Biol, McGill, Montreal, PQ, Canada. Changing the shape of the wing by directional selection in Drosophila melanogaster at two developmental temperatures. Blanche Bitner- Mathe, Danielle Tesseroli, Bianca Menezes. Dept Genetica, Univ Federal do Rio de Janeiro, RJ, Brazil. 58

POSTER SESSIONS See page 16 for presentation schedule Poster board number is in bold above title. The first author is the presenter. Full abstracts can be found online at drosophila-conf.org

479B 467B The genetic basis of color pattern evolution in D. malerkotliana. Sarah New Genes in Drosophila Quickly Become Essential for Development. A. Signor, Rachel Curtis, Artyom Kopp. University of California, Sidi Chen, Yong Zhang, Manyuan Long. Dept Ecology & Evolution, Davis, Davis, CA. Univ Chicago, Chicago, IL. 480C 468C Identification of conserved unannotated transcribed elements in the vestigial function is not limited to wing development in Tribolium. Drosophila phylogeny. Carlo G. Artieri, John H. Malone, David M. Courtney M. Clark, Yoshinori Tomoyasu. Zoology Department, Sturgill, Nicolas R. Mattiuzzo, Brian Oliver. LCDB, NIDDK, NIH, Miami University, Oxford, OH. Bethesda, MD.

469A 481A A quantitative framework provides insights to design features and Rapid Evolutionary Rewiring of a Structurally Constrained Eye evolution of enhancers. Thyago Duque1, Xin He2, Saurabh Sinha1. 1) Enhancer. Scott E. Barolo1, David B. Schwimmer1, Christina I. University of Illinois at Urbana Champaign; 2) University of California Swanson1,2. 1) Dept. of Cell & Developmental Biology, University of at San Francisco. Michigan Medical School, Ann Arbor, MI; 2) Current Address: Dept. of Biology, UNC Chapel Hill, Chapel Hill, NC 27599. 470B Evolution of the Hox gene fushi tarazu in arthropods. Alison Heffer1, 482B Yong Lu2, Jeff Shultz3, Leslie Pick1,2,3. 1) Prog. in Molecular and Cell Evolutionary significance of gene expression divergence of the neo-sex Biology, Univ Maryland, College Park, MD; 2) Dept. Cell Biology and chromosomes in Drosophila albomicans. Ching-Ho Chang1, Su Fang2, Molecular Genetics, Univ Maryland, College Park, MD; 3) Dept Chau-Ti Ting1,3, Hwei-yu Chang2,4. 1) Insitute of Ecology & Entomology, Univ Maryland, College Park, MD. Evolutionary Biology, National Taiwan Univeristy, Taiwan; 2) Biodiversity Research Center, Academia Sinica, Taiwan; 3) Department 471C of Life Science & Institute of Zoology, National Taiwan University, Building a dictionary of genetic effects. David Houle, Eladio Márquez. Taiwan; 4) Department of Entomology, National Taiwan University, Dept Biological Science, Florida State Univ, Tallahassee, FL. Taiwan.

472A 483C Mutations in a cholesterol oxygenase gene have turned Drosophila Using next-generation sequencing to investigate patterns of regulatory pachea into an obligate specialist species. Michael Lang1, Sophie divergence in Drosophila. Joseph D. Coolon1, Kraig R. Stevenson1, C. Murat2, Geraldine Gouppil1, Luciano M. Matzkin3, Takuji Joel McManus2, Brenton R. Graveley2, Patricia J. Wittkopp1. 1) Yoshiyama4, Émilie Guittard2, Hiroshi Kataoka4, Ryusuke Niwa4, Department of Ecology and Evolutionary Biology, University of René Lafont2, Chantal Dauphin-Villemant2, Virginie Orgogozo1,2. 1) Michigan, Ann Arbor, MI; 2) Department of Genetics and CNRS UMR7592, Institut Jacques Monod, Paris, France; 2) CNRS Developmental Biology, University of Connecticut Stem Cell Institute, UMR7622, Université Pierre et Marie Curie, 75005 Paris, France; 3) University of Connecticut Health Center, Farmington, CT. University of California, Division of Biological Sciences, La Jolla, California 92093-0116, USA; 4) University of Tsukuba, Tsukuba, 484A Ibaraki 305-8572, Japan. Arginine kinase gene arrangement in the phorid fly Megaselia scalaris. Justin Davis, Kristina Maynard, Jacob Crowley, Glen Collier. 473B University of Tulsa, Tulsa, , OK. Morphological homology vs. Developmental homology - a case study using insect wing veins. Tingjia Lao, Yoshinori Tomoyasu. 485B Department of Zoology, Miami University, Oxford, OH. Functional analyses of two nuclear transport retrogenes (Dntf-2r and Ran-like) in D. melanogaster. Susana Domingues, Esther Betrán. 474C Biology Department, The University of Texas at Arlington, Arlington, Developmental Genetic Mechanisms of Sensory System Evolution in TX. Drosophila prolongata. David Luecke, Artyom Kopp. University of California, Davis, Davis, CA. 486C Using correlated rates of protein evolution to predict reproductive 475A protein interactions. Geoffrey D. Findlay, Nathaniel L. Clark, Evolution of locomotor patterns in Drosophila species. Claudia M. Mariana F. Wolfner. Department of Molecular Biology and Genetics, Mizutani, Belu Mirela, Yunyi Yang. Dept Biol, Case Western Reserve Cornell University, Ithaca, NY. Univ, Cleveland, OH. 487A 476B RNA-seq in Drosophila hybrids reveals species specific gene regulation. Rescue of Bicoid patterning functions by divergent homeodomain Rita M. Graze1, Luis L. Novelo2, Victor Amin1, George Casella2, proteins. Jacqueline Moore1, Gözde Yucel1,2, Na-Eun Christine Yoo1, Sergey V. Nuzhdin3, Lauren M. McIntyre1,2. 1) Department of Stephen Small1. 1) Department of Biology, New York University, New Molecular Genetics and Microbiology, University of Florida, York, NY; 2) Stanford University School of Medicine, Stanford, CA. Gainesville, FL; 2) Department of Statistics, University of Florida, Gainesville, FL; 3) Section of Molecular and Computational Biology, 477C Department of Biological Sciences, University of Southern California, A possible contribution of abrupt in the evolution of beetle elytra. Los Angeles, CA. Padmapriyadarshini Ravisankar, Tingjia Lao, Yoshinori Tomoyasu. Zoology Department, Miami University, Oxford, OH. 488B Gene movement between chromosomes in Drosophila miranda. 478A Tatiana A. Gurbich, Doris Bachtrog. Department of Integrative Evolution of abdominal pigmentation in the montium subgroup of Biology, University of California, Berkeley, CA. Drosophila. Thaddeus Seher, Ondrej Podlaha, Artyom Kopp. Evolution and Ecology, University of California, Davis, Davis, CA.

POSTER SESSIONS See page 16 for presentation schedule Poster board number is in bold above title. The first author is the presenter. Full abstracts can be found online at drosophila-conf.org

489C 499A Does positive selection drive transcription factor binding site turnover? Genomic evolution of Drosophila miranda's neo-sex chromosomes. Qi A test in Drosophila cis-regulatory modules. Bin He, Martin Kreitman. Zhou, Doris Bachtrog. Department of Integrative Biology, University Ecology & Evolution, Univ Chicago, Chicago, IL. of California, Berkeley, Berkeley, CA.

490A 500B Gene loss from the Drosophila miranda neoY chromosome: expression Review of reported Drosophila species (Diptera: Drosophilidae) in levels matter. Vera B. Kaiser, Qi Zhou, Doris Bachtrog. Dep. of montane habitats in Colombia. Diana Alvarez. Dept Biol, Univ Integrative Biology, UC Berkeley, 3060 VLSB, Berkeley, CA-94720. Javeriana, Bogota, Bogota DC, Colombia.

491B 501C Population Genomics of Drosophila melanogaster Coding Sequences. The fast evolving neo-Y chromosome of Drosophila albomicans. Hwei- Grace Y. C. Lee, David J. Begun, Alisha K. Holloway, Charles H. yu Chang1, Chia-hao Cheng1, Ching-Ho Chang2. 1) Dept Langley. Department of Evolution and Ecology, University of Entomology, National Taiwan Univ, Taipei, Taiwan, Taiwan; 2) California, Davis, CA. Department of Life Science, National Taiwan University, Taipei 106, Taiwan. 492C Birth and rapid evolution of a new importin pair of proteins in 502A Drosophila. Nitin Phadnis, Harmit Malik. Division of Basic Sciences, The Genetic Basis of a Behavioral Adaptation in D. sechellia. Eric J. Fred Hutchinson Cancer Research Center, Seattle, WA. Earley, Corbin D. Jones. Dept. Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC. 493A Contribution of the Y chromosome to gene expression divergence 503B between Drosophila simulans and Drosophila sechellia. Timothy B. A new perspective on sexual conflict related topics: gene duplication, Sackton, Daniel Hartl, Bernardo Lemos. Organismic & Evol Bio, sex-biased expression and the location of sexually dimorphic traits. Harvard Univ, Cambridge, MA. Miguel Gallach Caballero, Esther Betrán. University of Texas at Arlington. B05A Life Science 501 S. Nedderman Drive, Arlington, TX 494B 76019-0498. A de novo Assembly of the Lucilia sericata (Diptera: Calliphoridae) Transcriptome with Alternative Splices: Genomic Tools for a Medically, 504C Agriculturally, Forensically, and Ecologically Important Blow Fly. Gene expression responses to single-copy deletions in Drosophila. Aaron M. Tarone1,3, Sing-Hoi Sze2, Joseph P. Dunham3, Brandi-lee Renhua Li, John H. Malone, Nicolas Mattiuzzo, Brian Oliver. Carey4, Peter L. Chang3, Fang Li5, Courtney Fjeldsted3, Maxwell J. Developmental Genomics Section, LCDB, NIDDK, National Institutes Scott4,5, Sergey V. Nuzhdin3. 1) Department of Entomology, Texas of Health, Bethesda, MD 20892. A&M University, College Station, TX; 2) Department of Computer Science and Engineering, Department of Biochemistry and Biophysics, 505A Texas A&M University, College Station, TX, 77843; 3) Molecular and The evolution of foraging behaviour and social interaction in larvae of Computational Biology, University of Southern California, Los Angeles, the genus Drosophila. Christen K. Mirth1,2, Hans C. P. Kelstrup2, CA 90089; 4) Institute of Molecular BioSciences, Massey University, Lynn Riddiford2. 1) Instituto Gulbenkian de Ciência, Oeiras, Portugal; Private Bag 11222, Palmerston North, New Zealand; 5) Department of 2) Janelia Farm Reseach Campus, Howard Hughes Medical Institute, Genetics, North Carolina State University, Campus Box 7614, Raleigh Ashburn, VA, U.S.A. NC 27695-7614. 506B 495C Preliminary genomic analysis of a DNA virus of Drosophila. Robert Characterizing the sex chromosomes of Aedes aegypti. Melissa A. Unckless. Department of Biology, University of Rochester, Rochester, Toups1, David W. Severson2, William A. Cresko3, Julian M. NY. Catchen3, Susan Bassham3, Matthew W. Hahn1. 1) Biology, Indiana University, Bloomington, IN 47401; 2) Department of Biological 507C Sciences, University of Notre Dame, Notre Dame, IN 46556; 3) Center Experimental selection of hypoxia-tolerant Drosophila melanogaster: for Ecology and Evolutionary Biology, University of Oregon, Eugene, Major role for Notch activation. Dan Zhou1, Nitin Udpa2, Merril OR 97403. Gersten2, DeeAnn Visk1,3, Ali Bashir2, Jin Xue1, Kelly Frazer1,2, James Posakony2,3, Shankar Subramaniam2,4, Vineet Bafna2,5, 496A Gabriel Haddad1,6,7. 1) Dept Pediatrics, Univ California, San Diego, La Assessing dosage compensation in a female-heterogametic tephritid. Jolla, CA; 2) Bioinformatics & Systems Biology Graduate Program, Beatriz Vicoso, Doris Bachtrog. UC Berkeley, Berkeley, CA. Univ California, San Diego, La Jolla, CA; 3) Division of Biological Sciences, Section of Cell and Developmental Biology, Univ California, 497B San Diego, La Jolla, CA; 4) Department of Bioengineering, Univ Evolution of complex gene structures in the 12 Drosophila genomes. California, San Diego, La Jolla, CA; 5) Department of Computer Luyi Wo1,2, Stephen Schaeffer1,2. 1) Department of Biology, Penn State Science and Engineering, Univ California, San Diego, La Jolla, CA; 6) U, University Park, PA; 2) Intercollege Program of Genetics, Penn State Department of Neuroscience, Univ California, San Diego, La Jolla, CA; U, University Park, PA. 7) Rady Children's Hospital, San Diego, CA.

498C 508A Mechanisms of spliceosomal intron gain and loss: an investigation and Evolution of Nora Virus Sequence Between Swedish and United States review using 12 Drosophila species. Paul Yenerall1, Leming Zhou2,3, Populations of Drosophila melanogaster . Darby Carlson1, Ethan Bradlee Krupa4, Mou-Chun Wang5. 1) Department of Biological Cordes1, Benjamin Klein1,2, Camilla Stoner1, Brad Ericson1, Dawn Sciences; 2) Department of Health Information Management; 3) Simon1, Kimberly Carlson1. 1) Biology Department, University of Department of Bioengineering; 4) Department of Computer Science; 5) Nebraska at Kearney, Kearney, NE; 2) Lexington High School, School of Information Sciences, University of Pittsburgh, Pittsburgh, PA Lexington, NE 68850. 15260.

POSTER SESSIONS See page 16 for presentation schedule Poster board number is in bold above title. The first author is the presenter. Full abstracts can be found online at drosophila-conf.org

509B 520A Phylogeny of Endogenous Dipteran Retroviral-Like Transposons. Jym Phenotypic variation of blastoderm embryos in natural populations of Mohler. Oakland, CA. Drosophila melanogaster. Sarah S. Saminadin-Peter, Angela DePace, Zeba Wunderlich, Arnaud Gelas, Meghan Bragdon, Kelly 510C Eckenrode. System Biology, Harvard Medical School, Boston, MA. Genome-wide analysis of a long-term evolution experiment with Drosophila. Molly K. Burke1, Joseph P. Dunham2, Parvin 521B Shahrestani1, Kevin R. Thornton1, Michael R. Rose1, Anthony D. Genetic architecture of adaptation to a novel environment from standing Long1. 1) Department of Ecology and Evolution, University of genetic variation. Christian W. Schloetterer, Pablo Orozco, Martin California Irvine, Irvine, CA 92697-2525; 2) Molecular and Kapun, Robert Kofler, Viola Nolte. Inst f Populationsgenetik, Computational Biology, University of Southern California, Los Angeles, Vetmeduni Vienna, Wien, Austria. CA 90098. 522C 511A Intra- and interspecific variation in multiple odorant receptors in the Genetic variation and divergence within and between two Drosophila cactophilic Drosophila mojavensis and D. arizonae is associated with melanogaster populations revealed by whole genome sequencing. cactus host utilization. Joel O. Schumacher, Luciano M. Matzkin. Daniel Campo, Courtney Fjeldsted, Tade Souaiaia, Joyce Kao, Ecology, Behavior and Evolution, University of California, San Diego, Sergey Nuzhdin. University of Southern California, Los Angeles, CA. La Jolla, CA.

512B 523A Patterns of Directional Asymmetry Between and Within Species in the Comparative analysis of intraspecific mtDNA polymorphism of four Genus Drosophila. Ashley Carter. California State University Long species of Drosophila virilis group. Svetlana Y. Sorokina1, Boris V. Beach, Long Beach, CA. Andrianov2, Anna I. Chekunova1, Vladimir G. Mitrofanov1. 1) Koltsov Inst Dev Biology, Moscow, Russian Federation; 2) Vavilov Inst 513C Gen Genet, Moscow, Russian Federation. Natural variation in commensal bacteria regulation across DGRP lines. Angela Early1, Andrew Clark1,2. 1) Field of Ecology and Evolutionary 524B Biology, Cornell University, Ithaca, NY; 2) Dept of Molecular Biology P element prevalence in Central Mexico Drosophila species. Aldo A. and Genetics, Cornell University, Ithaca, NY. Téllez-García, Juan R. Riesgo Escovar. Depto. de Neurobiología del Desarrollo, Instituto de Neurobiología, UNAM, Querétaro, Querétaro, 514A México. Natural variation and sexual antagonism in Drosophila species. James J. Emerson, Qi Zho, Doris Bachtrog. Dept Integrative Biology, 525C University of California Berkeley, Berkeley, CA. Climatic stress adaptations in Drosophila melanogaster along a latitudinal transect: Analysis of genetic and plastic effects. Dau Dayal 515B Aggarwal1, Ravi Parkash1, Bhawna Kalra2. 1) Department of Polymorphisms in chromatin accessibility state within D.melanogaster. Genetics, M.D. University, Rohtak124001, India; 2) Department of Aaron Hardin1, Xiao-Yong Li2, Michael B. Eisen1,2,3. 1) Department Biology, University of Haifa- Oranim, Tivon 36006,Israel. of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA; 2) California Institute of Quantitative Biology, University 526A of California, Berkeley, Berkeley, CA; 3) Howard Hughes Medical From QTL to neuron: mapping natural variation in Drosophila fecundity Institute, University of California, Berkeley, Berkeley, CA. to an underlying mechanism. Alan O. Bergland1,2, Marc Tatar2. 1) Dept. of Biology, Stanford University, Stanford, CA; 2) Dept. of 516C Ecology and Evolutionary Biology, Brown University, Providence, RI. Y variants tip the chromatin balance. Bernardo Lemos, Alan Branco, Pan-Pan Jiang, Daniel Hartl. Dept Org & Evol Biol, Harvard Univ, 527B Cambridge, MA. Polymorphism in neurological genes contribute to variation in female sperm use patterns. Clement Y. Chow, Mariana F. Wolfner, Andrew 517A G. Clark. Dept Molec Biol & Gen, Cornell Univ, Ithaca, NY. Geographic variation of cold and desiccation tolerance in the red flour beetle, Tribolium castaneum. David M. Linz, Benjamin N. Philip, 528C Sindhu Samba, Yoshinori Tomoyasu, Richard E. Lee, Jr. Zoology A genome wide association study to characterize natural genetic Department, Miami University, Oxford, OH. variation in mated lifespan, age-specific reproduction and their plastic response to dietary restriction. Mary F. Durham, Jeff Leips. Biological 518B Sciences Dept, UMBC, Baltimore, MD. Genitalic shape variation in the Drosophila mojavensis species cluster. Maxi Polihronakis Richmond, Therese Markow. Cell and 529A Devlopmental Biology, University of California, San Diego, La Jolla, Between-species differences in aggregation behavior occurs through a CA. locus on the X chromosome. Deniz Erezyilmaz1,2, David Stern1,2. 1) Ecology & Evolutionary Biolo, Princeton Univ, Princeton, NJ; 2) 519C Howard Hughes Medical Institute. Hitchhiking in the Drosophila melanogaster genome: specific targets and genomewide signatures of Darwinian selection. John E. Pool, 530B Charles H. Langley. Evolution and Ecology, Univ California, Davis, Quantitative genetics of the metabolic regulatory network. Anthony J. Davis, CA. Greenberg1, Sean R. Hackett1, Lawrence Harshman2, Andrew G. Clark1. 1) Dept Molec Biol & Gen, Cornell Univ, Ithaca, NY; 2) School of Biological Sciences, Univ of Nebraska, Lincoln, NE.

POSTER SESSIONS See page 16 for presentation schedule Poster board number is in bold above title. The first author is the presenter. Full abstracts can be found online at drosophila-conf.org

531C 543C Estimating complete genotype data from a collection of dense semi- A Repressive Activity of the MSL Complex. Lin Sun1,2, Harvey codominant SNP markers in the Drosophila Synthetic Population Fernandez2, Ryan Donohue2, James Birchler1,2. 1) Biological Sci Div, Resource (DSPR). Elizabeth G. King1, Stuart J. Macdonald2, Univ Missouri, Columbia, Columbia, MO; 2) Genetics Area Program, Anthony D. Long1. 1) Department of Ecology & Evolutionary Biology, Univ Missouri,Columbia,MO. UC Irvine, Irvine, CA; 2) Department of Molecular Biosciences, University of Kansas, Lawrence, KS. 544A Lumen formation in tracheal terminal cells - novel role of Microsomal 532A triacylglycerol transfer protein. Magdalena M. Baer1, Maria Leptin2, Mapping Quantitative Trait Loci of Toxicity Effects Post Chemotherapy Markus Affolter1. 1) Department of Cell Biology, Biozentrum, Treatment. Galina Kislukhin, Mahtab Jafari, Anthony Long. Ecology University of Basel, Klingelbergstrasse 50/70, 4056 Basel, Switzerland; and Evolutionary Biology, University of California, Irvine, Irvine, CA. 2) Institute for Genetics, University of Cologne, Zülpicher Str 47, 50674 Cologne, Germany. 533B Mapping Loci Contributing to ADH Enzyme Expression in Drosophila 545B melanogaster. Stuart J. Macdonald, Chris M. Merkes. Dept. Mipps are involved in multiple processes of Drosophila tracheal Molecular Biosciences, University of Kansas, Lawrence, KS. development. Yim Ling Cheng, Deborah Andrew. Cell Biology, Johns Hopkins School of Medicine, Baltimore, MD. 534C Identification of QTL contributing to larval to adult viability in the 546C presence of nicotine. Tara N. Marriage, Stuart J. Macdonald. Dept Trachealess (Trh) regulates all tracheal genes. Se-Yeon Chung, Cy Molecular Biosciences, Univ Kansas, Lawrence, KS. Chaves, Deborah Andrew. Dept Cell Biol, Johns Hopkins Univ, Baltimore, MD. 535A Genome-wide Association Mapping of Loci Contributing to Variation in 547A the Shape of the Posterior Lobe of Drosophila melanogaster. Casey L. Domains and amino acids of Crumbs required for regulating Drosophila McNeil, Clint L. Bain, Sophia S. Loschky, Stuart J. Macdonald. tracheal tube-size. Renée M. Robbins1, Milena Pellikka2, Ulrich Department of Molecular Biosciences, University of Kansas, Lawrence, Tepass2, Greg Beitel1. 1) Molecular Biosciences, Northwestern KS. University, Evanston, IL, USA; 2) Department of Cell and Systems Biology, University of Toronto, Toronto, ON, Canada. 536B Quantitive Genetic Mapping of Resistance to Starvation in Drosophila 548B melanogaster. Casey L. McNeil, Clint L. Bain, Stuart J. Macdonald. ZPR1 mediated EGF signaling is required for subcellular lumen Department of Molecular Biosciences, University of Kansas, Lawrence, formation. Oscar E. Ruiz, Mark M. Metzstein. Dept Human Genetics, KS. Univ Utah, Salt Lake City, UT.

537C 549C Mito-nuclear genetic effects on sperm performance in Drosophila. Jim Multiplexin promotes heart-specific lumen formation in Drosophila. Mossman, David Rand. Ecology and Evolutionary Biology, Brown Nofar Harpaz, Talila Volk. Molecular Genetics, Weizmann Institute of University, Providence, RI. Science, Rehovot, Israel.

538A 550A Additive and Dominance Effects on Drosophila melanogaster wings in Functions of a helix-loop-helix transcription factor, Extramacrochaetae, diallel crosses using the Drosophila Genetic Reference Panel. Jessica in development of left-right asymmetry in the Drosophila embryonic Nye, David Houle. Evolution and Ecology, Florida State University, hindgut. Ryo Hatori, Kiichiro Taniguchi, Naotaka Nakazawa, Tallahassee, FL. Mitsutoshi Nakamura, Reo Maeda, Kenji Matsuno. Tokyo University of Science, Yamazaki, Noda, Chiba, Japan. 539B Transgressive Segregation Under Laboratory Condition in Drosophila. 551B Ballagere P. Harini. Drosophila Culture Laboratory, Dept of Zoology, Building a complex protein network linking the membrane to the Bangalore University, Bangalore, Karnataka, India. cytoskeleton: impact of gene dosage on protein stoichiometry within the integrin adhesion complex in vivo. Yoshiko Inoue, Nicholas H. Brown. 540C The Gurdon Institute and Dept of PDN, University of Cambridge, U.K. The Durham sex-ratio meiotic drive in Drosophila simulans. Yun Tao, Linbin Zhang, Jennifer Kovacs, Hailian Xiao. Dept Biol, Emory 552C Univ, Atlanta, GA. gon1 encodes an ADAMTS matrix metalloprotease required for proper cell migration during embryogenesis. Afshan Ismat, Alan Cheshire, 541A Deborah Andrew. Dept Cell Biol, Johns Hopkins Sch Med, Baltimore, The genome of Drosophila athabasca and its application to speciation. MD. Karen M. Wong1, Doris Bachtrog1, Michael B. Eisen2,3. 1) Department of Integrative Biology, UC Berkeley, Berkeley, CA; 2) 553A Department of Molecular and Cell Biology, UC Berkeley, Berkeley, The blade runner gene of Drosophila is required for wing structure CA; 3) Howard Hughes Medical Institute, UC Berkeley, Berkeley, CA. maturation. Balaji G. Iyengar1,2, Laura Fung1, Fong Cho1, Amber Ablack1, John Lewis1. 1) Department of Oncology, University of Western Ontario, London Regional Cancer Centre. London, Ontario, Gametogenesis and Organogenesis Canada; 2) Hamilton Health Sciences, Hamilton, Ontario, Canada.

542B Unusual regulation of the X chromosome in the Drosophila male germline. Colin D. Meiklejohn, Emily Landeen, Jodi Cook, Daven C. Presgraves. Dept Biol, Univ Rochester, Rochester, NY. 62

POSTER SESSIONS See page 16 for presentation schedule Poster board number is in bold above title. The first author is the presenter. Full abstracts can be found online at drosophila-conf.org

554B 565A MAPK-dependent posttranslational regulation of Iroquios proteins. Spalt mediates an evolutionary conserved switch to fibrillar muscle fate. Natalia Barrios, Antonio S. Tutor, Rosario Hernández, Sonsoles Cornelia Schönbauer1, Jutta Distler2, Nina Jährling3, Martin Campuzano. Centro de Biologia Molecular Severo Ochoa, CSIC-UAM, Radolf4, Hans-Ulrich Dodt3, Manfred Frasch2, Frank Schnorrer1. 1) Madrid, Spain. Max-Planck-Institute of Biochemistry, Martinsried, Germany; 2) Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, 555C Germany; 3) Technical University of Vienna, Vienna, Austria; 4) A new role for the Drosophila Serum Response Factor. Francisco Research Institute of Molecular Pathology, Vienna, Austria. Javier Carmona Aldana, Juan Rafael Riesgo Escovar. Developmental Neurobiology and Neurophysiology Department. 566B Instituto de Neurobiología, Universidad Nacional Autónoma de México, Cdc42 is required during morphogenesis of the Drosophila heart and campus Juriquilla. Juriquilla, Querétaro, Mexico. genetically interacts with the tyrosine kinase Abelson. Georg Vogler1, Timothy Iafe1, Jiandong Liu2, Rolf Bodmer1. 1) Development and 556A Aging, Sanford-Burnham Medical Research Institute, La Jolla, CA; 2) Brg-P9: A putative Kunitz domain inhibitor of serine proteases involved Dept. Biochem. & Biophys., UCSF, San Francisco, CA. in imaginal disc morphogenesis. Sienna M. Sartori1, John Emery2, Rachel Morgan1, Cynthia Bayer1, Gregory Guild2, Laurence von 567C Kalm1. 1) Biology and Biomolecular Sciences Center, University of Spire, an actin nucleation factor, regulates cell division during Central Florida, Orlando, FL; 2) Department of Biology, University of Drosophila heart development. Peng Xu, Tamara Johnson, Jessica Pennsylvania, Philadelphia, PA. Stoller-Conrad, Robert A. Schulz. Department of Biological Sciences, University of Notre Dame, Notre Dame, IN. 557B Identification of Mechanisms Regulating Muscle Cell Identity. Krista 568A C. Dobi, Mary K. Baylies. Dept Dev Biol, Sloan-Kettering Inst, New Parthenogenesis in a Drosophila Yemanuclein-alpha meiosis I defective York, NY. mutant. Ounissa Ait-Ahmed1, Regis Meyer1,2, Ahmed Algazeery1, Michèle Capri1. 1) Inst de Genetique Humaine, CNRS UPR 1142, 558C Montpellier Cdx, France; 2) current address: Cell Cycle and Cancer Cross-interaction between tailup (tup) and collier (col) in determining Biology OMRF Oklahoma, USA. DA3 and DA2 muscle identity. Boukhatmi Hadi, Frendo Jean-louis, Enriquez Jonathan, Dubois Laurence, Vincent Alain. Centre de 569B Biologie du Développement, 118 rte de Narbonne 31062 Toulouse Nutrient Restriction Affects Polarized Transport in the Drosophila cedex 09, Toulouse, France. Ovary. Katherine M. Burn, Lynn Cooley. Gen, Cooley Lab, Yale Sch Med I-359, New Haven, CT. 559A The JAK/Stat pathway promotes mesoderm subdivision and maintains 570C cardiac integrity during embryogenesis. Aaron N. Johnson, Mayssa H. Analysis of Drosophila melanogaster Tudor: logic of a dynasty. Remi- Mokalled, Thomas N. Haden, Eric N. Olson. Department of Xavier Coux1,2, Sophia Ju-Yu Wang1, Ying Huang3, Rui-Ming Xu3,4, Molecular Biology, Univ. of Texas Southwestern Medical Center at Ruth Lehmann1. 1) Developmental Genetics Program, The Skirball Dallas, Dallas, TX. Institute, Howard Hughes Medical Institute, NYU School of Medicine, New York; 2) Université Paris Diderot - Paris VII, GC2ID Doctoral 560B School, Paris , France; 3) Structural Biology Program, The Skirball Two reporters are better than one: a genetic screen for novel regulators Institute, NYU School of Medicine, New York; 4) Institute of of mesoderm development. Aaron N. Johnson, Eric N. Olson. Biophysics, Chinese Academy of Sciences, Beijing, China. Department of Molecular Biology, UT Southwestern Medical Center at Dallas, Dallas, TX. 571A Defining the maternal effect lethal phenotype of E(var)3-9. Claire E. 561C Dolan, Karen S. Weiler. Department of Biology, West Virginia Determining Pvf Contributions to Cellular Proliferation, Migration and University, Morgantown, WV. Survival. Brendon D. Parsons. University of Alberta, Edmonton, Alberta, Canada. 572B Isolation of a novel regulator of the actin cytoskeleton. Tânia C. 562A Ferreira, André Rosa, Rui Martinho. Instituto Gulbenkian de Ciencia, Transcription factor erect wing (EWG) is involved in indirect flight Oeiras, Portugal. muscle patterning, development and maintenance in Drosophila. Mamta Rai, Upendra Nongthomba. Molecular Reproduction, Development 573C and Genetics, Indian Institute of Science, Bangalore, Karnataka, India. The Identification and Characterization of Novel Genes Involved in Cell Polarity Establishment. Sarah E. Kleinsorge, Caryn Navarro. 563B Department of Medicine/Genetics Program, Boston University School of Deficiency screening to identify novel genes that function during Medicine, Boston, MA. Drosophila myogenesis. Kate M. Rochlin1,2, Karen Beckett3, Mary Baylies1. 1) Dept Dev Biol, Sloan-Kettering Inst, New York, NY; 2) 574A Weill Cornell Graduate School of Biomedical Sciences, New york, NY; Characterization of RNA targets of the nuclear RNA-binding protein 3) National Institute for Medical Research, Mill Hill, London. Lark during oogenesis. Gerard P. McNeil1,2, Kirk Haltaufderhyde1, Christopher Ferrari2. 1) Department of Biology, York College/CUNY, 564C Jamaica, NY; 2) Program in Biology at the Graduate Center, CUNY, Identification of Genes Involved in Myonuclear Positioning During NY, NY. Muscle Development. Victoria K. Schulman1,2, Thomas J. Metzger1,2, Mu Xu1,2, Mary K. Baylies2. 1) Weill Cornell Graduate School of Medical Sciences, New York, NY; 2) Sloan-Kettering Institute, Developmental Biology Program, New York, NY.

POSTER SESSIONS See page 16 for presentation schedule Poster board number is in bold above title. The first author is the presenter. Full abstracts can be found online at drosophila-conf.org

575B 587B Argonaute 1 regulates germ cell division and oocyte determination in Top tips for organ shape: the role of tip cells in renal tubule Drosophila melanogaster. Mohd Ghows Mohd Azzam, Ji-Long Liu. morphogenesis. Helen Weavers, Helen Skaer. Department of Zoology, MRC Functional Genomics Unit, Department of Physiology, Anatomy University of Cambridge, United Kingdom. and Genetics, University of Oxford, Oxford, OX1 3QX, United Kingdom. 588C Mucin-type O-glycosylation is required for digestive system formation 576C and function in Drosophila. Liping Zhang, Kelly G. Ten Hagen. Room Investigating the role of Spindle-E in germline development. Kristen 4A400, building 30, NIDCR/NIH, Bethesda, MD. Mary Ott, Tram Nguyen, Caryn Navarro. Genetics and Genomics, Boston University Medical Center, Boston, MA. 589A multi sex combs (mxc) regulates histone mRNA processing and germ 577A cell behavior in the Drosophila testis. Severine Landais, Leanne Jones. Identification of Tramtrack69 Targets During Drosophila Dorsal Laboratory of Genetics, Salk Institute, La Jolla, CA. Appendage Tubulogenesis. Nathaniel Peters, Celeste Berg. Department of Genome Sciences and the Molecular and Cellular 590B Biology Program, University of Washington, Seattle, WA. Identifying Doublesex targets with DamID-seq. Emily Clough, Brian Oliver. LCDB/NIDDK/NIH, Bethesda, MD. 578B Female sterility and compromised eggshell integrity of drop-dead 591C mutants. Tayler Diane Sheahan, Laura E. Korthauer, Edward M. The Significance of Alternative Splicing to Germline Sex Blumenthal. Biological Sciences, Marquette University, Milwaukee, Determination. Shekerah Primus, Mark Van Doren. Johns Hopkins WI. University, Baltimore, MD.

579C 592A Age-dependent requirement for Upd3 in oogenesis. Claire M.-P. The role of doublesex in development of somatic sexual identity. Cale Venard, Liqun Wang, Travis Sexton, Douglas A. Harrison. D. Whitworth, Mark Van Doren. Dept Biol, Johns Hopkins Univ, Department of Biology, University of Kentucky, Lexington, KY. Baltimore, MD.

580A 593B Mapping and Characterization of baal, a mutation in a novel gene that Hrp48 functions as a moderator of Sxl expression to allow for proper results in Drosophila Sterility marked by Germ Cell Loss. Qiao Zhang, Notch expression and signaling in monomorphic organ development. Michael Buszczak. UT Southwestwern Medical Center, 6000 Harry Offer Gerlitz1, Yaron Suissa1, Yossi Kalifa2, Tama Dinur1, Patricia Hines Blvd. Dallas, TX. Graham3, Girish Deshpande3, Paul Schedl3. 1) Developmental Biology and Cancer Research, IMRIC, The Hebrew University- 581B Hadassah Medical School, Jerusalem, Israel; 2) Department of The bwk/shark pathway: toward understanding dorsal appendage Molecular Genetics, Weizmann Institute of Science, Rehovot Israel; 3) morphogenesis. Sandra G. Zimmerman, Celeste Berg. Genome Department of Molecular Biology, Princeton University, Princeton, NJ Sciences, University of Washington, Seattle, WA. 08540, USA.

582C 594C A role for the biogenic amines tyramine and octopamine in Drosophila The role of Drosophila doublesex in the development of a sexually sperm storage. Frank W. Avila1, Margaret C. Bloch Qazi2, Mariana dimorphic gonad. Erin Jimenez, Mark Van Doren. Johns Hopkins F. Wolfner1. 1) Dept Mol Biol & Gen, Cornell Univ, Ithaca, NY; 2) University, Baltimore, MD. Dept of Biol, Gustavus Adolphus College, St. Peter, MN. 595A 583A Possible roles in spermatid mitochondrial shaping for testis-specific Differential requirements for components of the apical PAR complex in paralogs of ATP synthase subunits. Tessa Campbell, Casie Genetti, subcellular morphogenesis. Tiffani A. Jones, Mark M. Metzstein. Chris Lima, Taylor Gunnell, Caroline Shaffner, Karen G. Hales. Human Genetics, University of Utah, Salt Lake City, UT. Department of Biology, Davidson College, Davidson, NC.

584B 596B Role of Notch and its targets in regulating myogenesis. Guillaume Zombie is Involved in Restricting Spermatogonial Proliferation Pézeron, Sarah Bray. Dpt of Physiology, Development and Intrinsically. Di Chen1,2, Bangxia Suo1, Shaowei Zhao1,2, Qing Neuroscience, University of Cambridge, Cambridge, United Kingdom. Geng1,2, Zhaohui Wang1. 1) Institute of Genetics and Developmental Biology, Chinese Academy of Science, Beijing; 2) Graduate School of 585C the Chinese Academy of Science. Temporal and spatial requirements for drop-dead expression. Christine L. Sansone, Edward M. Blumenthal. Biological Sci, Marquette Univ, 597C Milwaukee, WI. Role of CG4701 in mitochondrial morphogenesis during Drosophila melanogaster spermatogenesis. Dylan Coughtrey, Leah Smith, Hunter 586A Stone, Bevin English, Karen G. Hales. Department of Biology, Secondary cells in the male accessory gland contribute to the post Davidson College, Davidson, NC. mating response in Drosophila melanogaster. Jessica Sitnik1, Dragan Gligorov2, Robert Maeda2, François Karch2, Mariana Wolfner1. 1) 598A Molecular Biology and Genetics, Cornell University, Ithaca, NY; 2) Structural heterogeneity of the 26S proteasome in Drosophila Dept of Zoology and Animal Biology, University of Geneva, Geneva, spermatogenesis. Jing Dai, Xiazhen Li, Long Qin Wang, John Belote. Switzerland. Biology Deptartment, Syracuse University, Syracuse, NY.

POSTER SESSIONS See page 16 for presentation schedule Poster board number is in bold above title. The first author is the presenter. Full abstracts can be found online at drosophila-conf.org

599B 608B Lasp function in regulating actin filament dynamics in Drosophila. The cholesterol trafficking protein NPC1 is required for Drosophila Isabelle I. Fernandes, Lili Zhou, Frieder Schöck. Department of spermatogenesis. Chao Wang1,2, Zhiguo Ma1,2, Xun Huang1. 1) Key Biology, McGill University, Montreal, Quebec, Canada. Laboratory of Molecular and Developmental Biology,Institute of Genetics and Developmental Biology,Chinese Academy of Sciences, 600C Beijing , China; 2) Graduate School of Chinese Academy of Characterization of a candidate gene for ms(2)1400, a gene required for Sciences,Beijing , China. the internal structure of the Nebenkern in Drosophila spermatids. Lauren E. Ivey1, Tessa Campbell1, Cricket Wood2, Anthony Mahowald2, Margaret T. Fuller2, Karen G. Hales1. 1) Department of Immunity and Pathogenesis Biology, Davidson College, Davidson, NC; 2) Department of Developmental Biology, Stanford University School of Medicine, 609C Stanford CA. A screen for modifiers of a tyrosine kinase induced blood cell phenotype identifies new players in the cellular immune response and serves as a 601A model for leukemia. Ines Anderl1,2, Jesper Kronhamn2, Anni Kleino1, A transcription factor Samuel is involved in the regulation of germ cell Dan Hultmark1,2. 1) Institute of Medical Technology, University of proliferation in spermatogenesis. Hiroyuki Kose1, Masataka Okabe2, Tampere, Tampere, Finland; 2) Department of Molecular Biology, Kozo Matsumoto3, Hiromi Yasuhi4. 1) Dept of Life Science, Umeå University, Umeå, Sweden. International Christian University, Tokyo, Japan; 2) Dept. of Anatomy, The Jikei University School of Medicine, Tokyo, Japan; 3) Dept. of 610A Animal Medical Sciences, Kyoto Sangyo University, Kyoto, Japan; 4) PKD2 and DmelCed-12 act in parallel pathways during apoptotic cell National Institute of Genetics, Mishima, Japan. clearance. Nathalie C. Franc1,2, Emeline Van Goethem2,3, Christina Bakatselou2, Hui Xiao1. 1) Present address: The Department of 602B Genetics, The Scripps Research Institute, La Jolla, CA; 2) Medical The role of the bromodomain protein tBRD-1 during spermatogenesis. Research Council Cell Biology Unit. MRC Laboratory for Molecular Katja Leser1, Bridlin Barckmann1,2, Xin Chen3, Margaret T. Fuller4, Cell Biology and Anatomy and Developmental Biology Department, Renate Renkawitz-Pohl1, Christina Rathke1. 1) Developmental University College London, London, UK; 3) Present address: Institut de Biology, Philipps-Universität Marburg, 35043 Marburg, Germany; 2) Pharmacologie et Biologie Structurale, Toulouse, France. Institute of human genetics, Montpellier F-34396, France; 3) Johns Hopkins University, Baltimore, MD 21218-2685, USA; 4) Stanford 611B University School of Medicine, Stanford,CA 94305, USA. The plasticity of hemocyte lineages in Drosophila melanogaster. Viktor Honti, Gábor Csordás, Róbert Márkus, Éva Kurucz, Ferenc 603C Jankovics, István Andó. Institute of Genetics, Biol. Res. Ctr. of the THO complex is required for nuclear integrity and meiotic entry in Hung. Acad. Sci., Szeged, Hungary. Drosophila spermatocytes. Sungjin Moon, Yundoo Chung. Lifescience, Univ Seoul, Seoul, Korea. 612C Phagocytic Ability Changes With Age In Adult Drosophila. Lucas A. 604A Horn, Jeff Leips, Michelle Starz-Gaiano. Biological Sciences, Characterizing the function of nmd in mitochondrial morphogenesis and University of Maryland Baltimore County, Baltimore, MD. in cytokinesis during spermatogenesis in Drosophila melanogaster. Sarah Catherine Pyfrom1, Leah Smith1, Samantha Lightcap1, Helen 613A White-Cooper2, Karen G. Hales1. 1) Department of Biology, Davidson Evolution of Toll-Mediated Innate Immunity in Drosophila. Scott College, Box 7118, Davidson, NC, 28035; 2) School of Biosciences, Lindsay, Steven Wasserman. Cell & Developmental Biology, Univ. Cardiff University, Cardiff, Wales, UK. California, San Diego, La Jolla, CA.

605B 614B Prenyl processing in Drosophila: a conserved enzyme plays a critical Protease targets and trafficking receptors of the Nec serpin-family role in the Drosophila male germline. Sandra R. Schulze, Katie inhibitor in the innate immune response. Veronika Mikitova, Sandra Adolphsen, Amanda Amell, Nathan Havko, Sara Kevorkian, Kyle Soukup, Arantza Sanz-Parra, David Gubb. Functional Genetics, Mears, Hayley Neher. Dept Biol, Western Washington Univ, CICbioGUNE, Derio, Bizkaia, Spain. Bellingham, WA. 615C 606C A genome-wide approach to characterize new genes involved in the Loss of Function Alleles of the p50 Subunit of Dynactin Reveal a Role maintenance of hematopoietic progenitors in the Drosophila Lymph for Cytoplasmic Dynein in the Post-Meiotic Differentiation of Gland. Justine Oyallon1, Delphine Pennetier1, Ismael Morin1, Drosophila Sperm. Stephanie Skelly1, Tatsuhiko Noguchi2, Marta Sebastien Dejean2, Alain Vincent1, Michele Crozatier1. 1) Centre de Lenartowska3, Jason Duncan1. 1) Department of Biology, Willamette Biologie du Developpement, UMR 5547 CNRS, University of Toulouse University, Salem, OR; 2) Laboratory for Morphogenetic Signaling, 3, Toulouse, France; 2) Biostatistic Platform, Genopole, Toulouse, Center for Developmental Biology, RIKEN Kobe, Japan; 3) Institute of France. General and Molecular Biology, Laboratory of Developmental Biology, Nicolaus Copernicus University, Torun, Poland.

607A Drosophila Z2-5584 line carries a mutation in a nuclear mRNA export gene (rae1) responsible for male sterility. Silvia Volpi1, Barbara T. Wakimoto2, Giorgio Prantera1. 1) Dept. Agrobiology & Agrochemistry, Univ Tuscia, Viterbo, Italy; 2) Dept. of Biology, University of Washington, Seattle, WA 98195 USA.

POSTER SESSIONS See page 16 for presentation schedule Poster board number is in bold above title. The first author is the presenter. Full abstracts can be found online at drosophila-conf.org

616A 625A Cofilin regulator 14-3-3 is an evolutionarily conserved protein required The role of low protein diets and nutrient signaling in the pathogenic for phagocytosis and microbial resistance. Leena-Maija Vanha-aho1, survival of Drosophila. Jung-Eun Lee1, Isaac Edery2, Scott Pletcher1. Johanna Ulvila1,2, Anni Kleino1,3, Mari Vähä-Mäkilä2, Milka 1) Department of Molecular and Integrative Physiolgy, University of Vuoksio1, Sinikka Eskelinen4, Dan Hultmark1,3, Christine Kocks5, Michigan, Ann Arbor, MI; 2) Department of Molecular Biology and Mikko Hallman2, Mataleena Parikka1, Mika Rämet1,6. 1) Institute of Biochemistry, Rutgers University, Piscataway, NJ. Medical Technology, 33014 University of Tampere, Finland; 2) Department of Pediatrics and Biocenter Oulu, 90014 University of Oulu, 626B Finland; 3) Department of Molecular Biology, Umeå University, S-901 JNK/FOXO signaling regulates the expression of Drosophila 87 Umeå, Sweden; 4) Department of Pathology and Biocenter Oulu, peroxiredoxin V during immune response. Kyu-Sun Lee1, Hye-Mi 90014 University of Oulu, Finland; 5) Massachusetts General Hospital Ahn1,2, Dong-Seok Lee2, Kweon Yu1. 1) Aging Res Ctr, KRIBB, and Harvard Medical School, Boston, Massachusetts 02115, USA; 6) Daejeon, Korea; 2) College of Natural Sciences, Kyungpook National Department of Pediatrics, Tampere University Hospital, Tampere, University, Daegu, Korea. Finland. 627C 617B The population genetics of Drosophila viruses in the wild. Darren J. Entomopathogenic bacterium Pseudomonas entomophila causes a global Obbard, Claire L. Webster, Ben Longdon. Institute of Evolutionary translation inhibition in Drosophila melanogaster gut triggered by the Biology and Centre for Immunity Infection and Evolution, University of host oxidative stress response. Sveta Chakrabarti, Nicolas Buchon, Edinburgh, Edinburgh, UK. Bruno Lemaitre. Global Health Institute EPFL/SV/GHI, Lausanne, Switzerland. 628A Odor-based bioenhanced transmission of pathogen by Drosophila 618C melanogaster. Kiyoshi Okado, Naoaki Shinzawa, Shinya Fukumoto, Disappearing Phenotypes: The contribution of diet to immune Hirotaka Kanuka. NRCPD, Obihiro Univ Agri & Vet Med, Obihiro, robustness. Moria C. Chambers, David Schneider. MicroBiol & Japan. Immunology, Stanford Univ, Stanford, CA. 629B 619A Dosage compensation as a target of Spiroplasma-induced male killing in Drosophila immune responses to entomopathogenic nematodes and their Drosophila melanogaster. Michelle A. Schulte, Patrick M. Ferree. symbiotic bacteria. Ioannis Eleftherianos, Julio Cesar Castillo. Joint Science Department, Claremont McKenna, Pitzer, and Scripps Department of Biological Sciences, Institute for Biomedical Sciences, Colleges, Claremont, CA 91711. The George Washington University, Washington, D.C. 630C 620B Hemolymph clotting and immunity. Ulrich Theopold1, Zhi Wang1, Pseudomonas aeruginosa RhlR is required to neutralize the cellular Pavel Dobes1,2, Pavel Hyrsl1,2. 1) Department of Molecular Biology & immune response in a Drosophila melanogaster oral infection model. Functional Genomics, University of Stockholm, 10691 Stockholm, Dominique X. Ferrandon1, Stefanie Limmer1, Samantha Haller1, Sweden; 2) Department of Animal Physiology & Immunology, Institute Janice Lee2,4, Rhonda Feinbaum3,4, Christine Kocks2,4, Frederick of Experimental Biology, Masaryk University, 611 37 Brno, Czech Ausubel3,4. 1) IBMC, CNRS UPR 9022, Strasbourg, France; 2) Republic. Department of Pediatrics, Harvard Medical School; 3) Department of Genetics, Harvard Medical School; 4) Department of Molecular 631A Biology, Massachusetts General Hospital, Simches Research Building The enemy of my enemy is my friend: Pseudomonas aeruginosa CPZN7250, 185 Cambridge St., Boston, MA 02114, USA. selected for resistance to lytic bacteriophage are less virulent to their Drosophila host. Heather Wilson1, Jason Behnke2, Aaron Moiser2, 621C Nathaniel Cady2, Ing-Nang Wang1, Kurt McKean1. 1) State The Serine Protease Inhibitor SpnI is involved in immunity to fungal University of New York at Albany, Biological Sciences; 2) State infections through the pattern-recognition signalling pathway. Susana University of New York at Albany, College of Nanoscale Science & Garcia-Sanchez, Ane Fullaondo, Arantza Sanz Parra, So Young Engineering. Lee, David Gubb. CIC Biogune, Derio, Vizcaya, Spain. 632B 622A Ecdysone Control of Innate Immune Responses. Neal Silverman1, Anthrax toxins cooperatively inhibit endocytic recycling by the Florentina Rus1, Thomas Flatt2,3, Marc Tatar2. 1) Med/Div Infectious Rab11/Sec15 exocyst. Annabel E. Guichard, Beatriz Cruz-Moreno, Dis, Univ Massachusetts Med Sch, Worcester, MA; 2) Ecology and Adrianne Kurciyan, Ethan Bier. Dept Biol, Univ California, San Evolutionary Biology Brown University, Providence RI; 3) Institute of Diego, La Jolla, CA. Population Genetics Department of Biomedical Sciences University of Veterinary Medicine Vienna. 623B The interactions of gut microbiota and the innate immune system in 633C response to pathogenic infection. Virginia M. Howick, Adam CN Imbalance Effects of fat metabolism to immune responses in Drosophila. Wong, Brian P. Lazzaro, Angela E. Douglas. Cornell University, Kyung Han Song, David Schneider. School of Medicine, Department Ithaca, NY. of Microbiology and Immunology, Stanford University, Stanford, CA.

624C 634A Expression and specificity of a candidate immune recognition protein in Ninjurin A and Drosophila Immunity. Sarah M. Broderick, Andrea Drosophila. Erin S. Keebaugh, Todd A. Schlenke. Dept Biol, Emory Page-McCaw. Cell and Developmental Biology, Vanderbilt University, Univ, Altanta, GA. Vanderbilt Medical Center, Nashville, TN.

POSTER SESSIONS See page 16 for presentation schedule Poster board number is in bold above title. The first author is the presenter. Full abstracts can be found online at drosophila-conf.org

635B 643A Differential activity of deubiquitinating enzymes regulate Imd Natural genetic variation in aggressiveness predicts social structure and ubiquitination and immune signalling. Marie-Odile Fauvarque1,2,3, male reproductive fitness in Drosophila. Julia B. Saltz1,2, Sergey Elodie Engel1,2,3, Magda Mortier1,2,3, Emmanuel Taillebourg1,2,3, Nuzhdin2. 1) Dept Population Biol, Univ California, Davis, Davis, CA; Dominique Thevenon1,2,3. 1) Inst. of life science research and 2) Molecular and Computational Biology, University of Southern technologies, CEA-Grenoble, Grenoble, France; 2) Inserm, Grenoble, California, Los Angeles CA. France; 3) UJF, Grenoble, France. 644B 636C kayak modulates circadian behavior in Drosophila melanogaster. Jinli Cactus localization during immune pathway activation. Shiva Ling1, Raphaëlle Dubruille1,2, Patrick Emery1. 1) Department of Seyedoleslami Esfahani, Åsa Holm, Tove Önfelt Tingvall, Gunnel Neurobiology, Univerisity of Massachusetts Medical School, Worcester, Björklund, Ylva Engström. Dep. of Molecular Biology and Functional MA; 2) Current: Centre de Génétique Moléculaire et Cellulaire, Genomics. Stockholm University, Stockholm, Stockholm, Sweden. Université Claude Bernard Lyon I, Mendel, Villeurbanne Cedex, France.

637A 645C Blood cell homing and self-renewal in the Drosophila larval Jim Lovell, A Neural Transcription Factor with Roles in Behavioral hematopoietic system. Kalpana Makhijani1, Brandy Alexander1, Responses and Gamete Development. Kathleen M. Beckingham, Sonia Tsubasa Tanaka1, Atsushi Miyawaki4, Katja Brückner1,2,3. 1) Bjorum, Rebecca A. Simonette, William J. Deery, Raul Alanis. Dept Department of Cell and Tissue Biology, University of California San Biochem & Cell Biol, Rice Univ, Houston, TX. Francisco, 513 Parnassus Ave, San Francisco, CA, USA; 2) Department of Anatomy, University of California San Francisco, 513 Parnassus Ave, 646A San Francisco, CA, USA; 3) Eli and Edythe Broad Center of Juvenile hormone modulates the maturation of female receptivity in Regeneration Medicine and Stem Cell Research, University of Drosophila melanogaster. Julide Bilen, Lynn Riddiford. Janelia Farm California San Francisco, 513 Parnassus Ave, San Francisco, CA, USA; Research Campus, Howard Hughes Medical Institute Ashburn, VA. 4) RIKEN Brain Science Institute , 2-1 Hirosawa, Wako, Saitama, Japan. 647B Functional Role of Flight Muscle in Male Courtship Song of Drosophila 638B melanogaster. Samya Chakravorty, Matthew Wajda, Jim Vigoreaux. Differential Gene Expression Related to Nora Virus Infection of Department of Biology, University of Vermont. Drosophila melanogaster . Ethan Cordes, Kimberly Carlson. Biology Department, University of Nebraska at Kearney, Kearney, NE. 648C A novel GPCR is required in fru neurons for male courtship behavior. 639C Brigitte Dauwalder, Yuanli Li, Valbona Hoxha, Chamala Lama. Stress-induced activation of the transcription factor dFoxO and its cross Dept Biol/Biochem, Univ Houston, Houston, TX. regulation with innate immune reactions in the respiratory epithelium of the fruit fly Drosophila melanogaster. Karin A. Uliczka1,2, Holger 649A Heine1, Thomas Roeder2. 1) Dept. of Immunology and Cell Biology, Socially-responsive genes and their role in Drosophila melanogaster Div. of Innate Immunity, Research Center Borstel, Borstel, Germany; 2) male reproductive behaviors. Lisa L. Ellis1,2, Ginger E. Carney2. 1) Dept. of Zoophysiology, Institute of Zoology, Christian-Albrechts- Entomology, Texas A&M University, College Station, TX; 2) Biology, University of Kiel, Kiel, Germany. Texas A&M University, College Station, TX.

640A 650B Wolbachia promote stem cell division and display tropism for the Chromatin regulators control the formation of neural sexual dimorphism germline stem cell niche. Eva M. Fast1, Michelle E. Toomey1,2, in Drosophila. Hiroki Ito1,2,3, Masayuki Koganezawa1, Manabu Kanchana Panaram1, Barrett Steinberg1, Horacio M. Frydman1,2. 1) Ote1,2, Ken Matsumoto2, Chihiro Hama3, Daisuke Yamamoto1,2. 1) Department Biology, Boston University, Boston, MA; 2) National Graduate School of Life Sciences, Tohoku University, Sendai, Japan; 2) Emerging Infectious Disease Laboratory, Boston University, Boston Advanced Institute for Science and Engineering, Waseda University, MA. Tokyo, Japan; 3) Center for Developmental Biology, RIKEN, Kobe, Hyogo, Japan. 641B Wolbachia determine differential stem cell niche tropism in the 651C Drosophila ovary and testes. Michelle E. Toomey1,2, Kanchana Rival-induced increased mating duration of Drosophila male is Panaram1, Eva Fast1, Catherine Beatty1, Horacio Frydman1,2. 1) dependent on the visual stimulus, circadian neural pathways, and Biology, Boston University, Boston, MA; 2) National Emerging ellipsoid body function. Woo Jae Kim, Yun Nung Jan. HHMI, Infectious Disease Laboratory (NEIDL), Boston University, Boston, Physiology, Biochemistry, and Biophysics Dept, UCSF, SF. MA. 652A Influence of the Male’s Wing Shape for their Success in Drosophila Neural Physiology and Behavior melanogaster Mating. Bianca F. Menezes1, Felipe M. Vigoder2, 2 1 Alexandre A. Peixoto , Blanche C. Bitner-Mathé . 1) Genetic Dept, 642C LGPD, UFRJ, RJ; 2) Oswaldo Cruz Institution, LBMI, FIOCRUZ, RJ. The role of tailless in the adult pars intercerebralis in Drosophila aggression. Krystle J. Nomie1, Herman Dierick1,2,3. 1) Molecular and 653B Human Genetics, Baylor College of Medicine, Houston, TX; 2) Investigation of octopamine’s role in the ovulin-dependent increase in Department of Pathology and Immunology, Baylor College of Medicine, ovulation. C. Dustin Rubinstein, Mariana F. Wolfner. Molecular Houston, TX; 3) Department of Neuroscience, Baylor College of Biology & Genetics, Cornell University, Ithaca, IL. Medicine, Houston, TX.

POSTER SESSIONS See page 16 for presentation schedule Poster board number is in bold above title. The first author is the presenter. Full abstracts can be found online at drosophila-conf.org

654C 665B An RNAi Screening for Fast Evolving Genes involved in male mate Recruitment of Dopamine Neurons into the Stress Response Circuitry. choice in Drosophila melanogaster. Rui S. Sousa-Neves1, Youngmin Kathryn J. Argue, Ariel Hofman, Wendi S. Neckameyer. Chu1, Joseph Schinaman1, Ramon N. dos Santos2, Alexandre Rosas2. Pharmacological and Physiological Sciences, Saint Louis University 1) Biol, Case Western Reserve Univ, Cleveland, OH; 2) Dept of Physics, School of Medicine, St. Louis, MO. Universidade Federal da Paraíba. 666C 655A A non-binary expression approach to generating brain-dopamine Mapping brain regions required for female acceptance. Rui Sousa- deficient Drosophila. K. Cichewicz1, M. Iché-Torres2, S. Birman2, J. Neves, Joseph Schinaman. Biology, Case Western Reserve Univ, Hirsh1. 1) Biology, University of Virginia, Charlottesville, VA; 2) Cleveland, OH. CNRS, ESPCI Paris, France.

656B 667A A Drosophila model for analyzing ion and volume homeostasis in the Relative positioning of histaminergic to serotonergic cells in the larval nervous system. William M. Leiserson1, Biff Forbush2, Haig CNS. Kelsey Crowley2, Martin Burg1,2. 1) Cell and Molecular Keshishian1. 1) MCD Biology Dept., Yale University, New Haven, CT; Biology; 2) Biomedical Sciences, Grand Valley State University, 2) Cellular and Molecular Physiology Dept., Yale University School of Allendale, MI. Medicine, New Haven, CT. 668B 657C Using a the Drosophila vesicular monoamine transporter as a sensitized Long-term Effects of Early Application of Juvenile Hormone. Kathryn genetic background to identify pathways that regulate aminergic J. Argue, Amber Yun, Wendi S. Neckameyer. Pharmacological and signaling. Hakeem O. Lawal, Logan Roberts, Jennifer Jang, Richard Physiological Sciences, Saint Louis University School of Medicine, St. S. Hadi, Varun Shahi, Dianne Pulido, Audrey Chen, David E. Louis, MO. Krantz. Psychiatry & Biobehavioral Sci, Univ California, Los Angeles, Los Angeles, CA. 658A Resilin RNAi alters form and function of wing hinge tendon in a 669C transgenic fruit fly. D. Neff1, J. Galloway2, J. Hogan1, N. Wang2, S. A glutamate transporter mutant that causes episodic ataxia and Collier1. 1) Biology Dept, Marshall U, Huntington, WV; 2) Fairland HS, hemiplegic migraine in humans disrupts glial cell morphology in Lawrence Co, OH. Drosophila. Christine N. Serway1, Hafsa Mamsa2, Christine Djapri2, Cuiwen He2, Harrison Hasanuddin2, Jasmine Fung2, Robert W. 659B Baloh2, David E. Krantz1,3, Joanna C. Jen2, Jijun Wan2. 1) Semel Eclosion Gates the Competence for Wing Expansion in Drosophila. Institute, UCLA School of Medicine, Los Angeles, CA; 2) Department Nathan Peabody, Benjamin White. Lab of Molecular Biology, of Neurology, UCLA School of Medicine, Los Angeles, CA; 3) NIMH/NIH, Bethesda, MD. Department of Psychiatry and Biobehavioral Sciences, UCLA School of Medicine, Los Angeles CA. 660C Non-genomic actions of the steroid hormone ecdysone on behavioral 670A plasticity in adult Drosophila. Hiroshi Ishimoto1, Zhe Wang2, Chun- Handedness in Drosophila locomotor behavior. Sean M. Buchanan, Fang Wu2, Toshihiro Kitamoto1,3. 1) Department of Anesthesia, Benjamin L. de Bivort. The Rowland Institute at Harvard, Cambridge, College of Medicine; 2) Department of Biology, College of Liberal Arts MA. and Sciences; 3) Interdisciplinary Programs in Genetics and Neuroscience, University of Iowa, Iowa City, IA. 671B A post-embryonic lineage of Insulin-like peptide 7 (ILP7)-expressing 661A neurons mediates egg-laying in Drosophila. Monica C. Castellanos, Dissecting the role of Drosophila Orb2 in long- term memory. Douglas W. Allan. Cellular and Physiological Sciences, University of Sebastian Kruettner, Barry J. Dickson, Krystyna Keleman. IMP - British Columbia, Vancouver, British Columbia, Canada. Research Institute of Molecular Pathology, Vienna, Austria. 672C 662B Automated biomechanical characterization of walking behavior in flies. The Therapeutic Role of Neurotrophic Factor Under Regulated Benjamin L. de Bivort1, James Kain1, Chris Stokes1, Quentin Expression in Drosophila Brain. Ekatherina Nikitina, Anna Gaudry2, XIangzhi Song1, Rachel Wilson2, James Foley1. 1) Rowland Medvedeva, Elena Savvateeva-Popova. Dept Neurogenetics, Pavlov Institute, Harvard University, Cambridge, MA; 2) Harvard Medical Inst Physiology, St Petersburg, Russian Federation. School, Boston MA.

663C 673A Developmental timing defects caused by an Imp-L2 mediated local Larval Floor Burn: An ROS-activated nociceptor mediates larval decrease of insulin signaling. Ladan Sarraf-Zadeh, Hugo Stocker, aversion to high friction locomotion. Wayne A. Johnson, Myung Jun Katja Koehler, Ernst Hafen. Institute of molecular systems biology, Kim, Joshua A. Ainsley. Dept Molec Physiol/Biophysics, Univ Iowa, ETH Zurich, Switzerland. Iowa City, IA.

664A 674B Molecular dissection of the developing Drosophila CCAP-neuron Idiosyncratic behavior in individual Drosophila revealed by an network. Lyubov Veverytsa, Douglas Allan. Department of Cellular automated phototactic screening device. James Kain, Christopher and Physiological Sciences, University of British Columbia, Vancouver, Stokes, Benjamin de Bivort. The Rowland Institute at Harvard, BC, V6T 1Z3 Canada. Cambridge, MA.

POSTER SESSIONS See page 16 for presentation schedule Poster board number is in bold above title. The first author is the presenter. Full abstracts can be found online at drosophila-conf.org

675C 686B Novel cytochrome P450, Cyp6a17, is required for temperature Variations of larval social behaviors in Drosophila wild-derived inbred preference behavior in Drosophila. Jongkyun Kang, Kwang-Wook lines. Beika Lu, Whitney Pennington, Yehuda Ben-Shahar. Biology, Choi. Department of Biological Sciences, KAIST, Daejeon, Korea. Washington University in St. Louis, St. Louis, MO.

676A 687C Recovery sleep enhances survival during bacterial infection in Dual Roles for the Gustatory Receptor 43a in taste perception and Drosophila. Tzu-Hsing Kuo, Julie Williams. Center for Sleep and nutrient sensing. Tetsuya Miyamoto, Xiangyu Song, Hubert Amrein. Respiratory Neurobiology, University of Pennsylvania School of Molecular and Cellular Medicine, Texas A&M Health Science Center, Medicine, Philadelphia, PA. College Station, TX.

677B 688A 3D Digital Atlas Guided Microsurgery of GAL4 Patterns of a Microbial manipulation of animal behavior: investigating the molecular Drosophila Brain. Hanchuan Peng. Peng Lab, HHMI, Ashburn, VA. basis of Drosophila- fungi associations. Kelly M. Schiabor1, Michael B. Eisen1,2. 1) Department of Molecular and Cell Biology, University of 678C California, Berkeley, Berkeley, CA; 2) Howard Hughes Medical Inst. A Wild-Derived Advanced Intercross Panel of Chromosome Substitution Lines for High Resolution QTL Mapping of Startle 689B Behavior in Drosophila melanogaster . Yazmin L. Serrano1,2, Akihiko A specific role for Myb in generating a precise receptor-to-neuron map H. Yamamoto1,2, Trudy F. C. Mackay2,3, Robert R. H. Anholt1,2,3. 1) in the olfactory system. Choon Kiat Sim1, Joe Lipsick1, Department of Biology, North Carolina State University, Raleigh, NC; Anandasankar Ray2. 1) Department of Pathology and Genetics, 2) W.M. Keck Center for Behavioral Biology; 3) Department of Stanford University, CA; 2) Entomology, University of California Genetics, North Carolina State University, Raleigh, NC. Riverside, CA.

679A 690C Regulation of locomotor behavior depends on isoform-specific action of Expression and Function of Drosophila sugar receptors. Jesse Slone1, CASK in the central nervous system. Justin Slawson, Elena Kuklin, Xiangyu Song1, Joseph Daniels2, Christopher Jagge1, Tetsuya Konark Mukherjee, Lilly Ostrovsky, Leslie Griffith. Biology, Miyamoto1, Hubert Amrein1. 1) Molecular and Cellular Medicine, Brandeis University, Waltham, MA. Texas A&M Health Science Center, College Station, TX, 77843; 2) Duke University Medical Center, Durham, NC, 27710. 680B Differential Roles of Drosophila CREB Isoforms in Drug Tolerance. 691A Benjamin Troutwine, Nigel Atkinson. Institute for Cellular and The larval neuromuscular junction and its presynaptic active zone: Molecular Biology, University of Texas at Austin. Bruchpilot as one organizer of structure and function. Sara Mertel1, Wernher Fouquet2, Harald Depner1, David Owald2, Carolin 681C Wichmann2, Robert Kittel3, Stefan Hallermann4, Stephan Sigrist1,2. Frequent Origins of Brain Genes in the Olfactory System Driving the 1) Institute of Biology/Genetics, Free University Berlin, 14195 Berlin, Evolution of Foraging Behavior. Sidi Chen1, Maria Spletter2, Liqun Germany; 2) Cluster of Excellence NeuroCure, Charité, 10117 Berlin, Luo2, Manyuan Long1. 1) Dept. Ecology & Evolution, Univ Chicago, Germany; 3) Institute of Physiology, University of Würzburg, 97070 Chicago, IL; 2) Dept. Biology, Stanford Univ, Stanford, CA. Würzburg, Germany; 4) Carl-Ludwig-Institute of Physiology, Medical Faculty, University of Leipzig, 04103 Leipzig, Germany. 682A Hedgehog signaling mediates nociceptive sensitization in Drosophila larvae. Michael J. Galko, Juyeon Jo, Daniel T. Babcock. Department Neurogenetics and Neural of Biochemistry and Molecular Biology, MD Anderson Cancer Center, Houston, TX, USA. Development

683B 692B touch insensitive larva B and smetana Genes Encoding Leucine-Rich Functional Diversity of Robo Receptors and the Evolution of Axon Repeat Proteins Cooperate In Ciliary Function. Julie Jacobs, Ryan Guidance. Tim Evans, Greg Bashaw. Dept of Neuroscience, University Kavlie, Daniel Eberl. University of Iowa, Dept. of Biology, Iowa City, of Pennsylvania School of Medicine, Philadelphia, PA. IA 52242 USA. 693C 684C Characterizing M9.17, a strong dominant enhancer of the trio and abl The Drosophila TRPA channel Painless is essential for sensing the mutant phenotypes. Eric C. Liebl, April R. Fields, Marcus J. Geer, naturally occurring insect repellent geraniol. Sang Hoon Kim, Young Lindsey J. Korbel, Brian T. Lynch, Katherine C. Palozola. Dept Kwon, Youngseok Lee, Craig Montell. Departments of Biological Biol, Denison Univ, Granville, OH. Chemistry and Neuroscience, Center for Sensory Biology, The Johns Hopkins University School of Medicine, Baltimore, MD. 694A Drosophila CCN is necessary for adult optic lobe transmedullary neuron 685A differentiation and outgrowth. Qin Yu1, Minh Hong2, Sarah J. Certel1. A family of putative taste receptors. Tong-Wey Koh1, Shannon 1) Center for Structural and Functional Neuroscience and Division of Stewart1, Jeeyun Chung2, John Carlson1,2. 1) Molecular Cellular & Biological Sciences, University of Montana, Missoula, MT; 2) Stem Developmental Biology, Yale University, New Haven, CT; 2) Program Cell Institute, University of Minnesota, Minneapolis, MN. in Biological and Biomedical Sciences, Yale University, New Haven, CT. 695B Temporal, positional and asymmetric cues control neural lineage topology and size by regulating the cell cycle machinery. Magnus Baumgardt, Daniel Karlsson, Erika Lundin, Ryan MacDonald, Carina Ulvklo, Caroline Bivik, Stefan Thor. Dept Clin Exper Med, Linkoping Univ Med Sch, Linkoping, Sweden. 69

POSTER SESSIONS See page 16 for presentation schedule Poster board number is in bold above title. The first author is the presenter. Full abstracts can be found online at drosophila-conf.org

696C 705C The Role of Drosophila AP180 (LAP) in Reconstitution of Synaptic Drosophila GIT interacts with Stoned B involved in endocytosis and Vesicles. Phillip Vanlandingham, Hong Bao, Lerin Chastain, synaptic vesicle recycling. Rui Tian1,3, Jasmin Podufall2, Carolin Chelsea Springer, Bing Zhang. Dept of Zoology, University of Wichmann1, Yong Qing Zhang3, Volker Haucke2, Stephan Sigrist1. Oklahoma, Norman, OK. 1) Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Da tun Road, Chao Yang District, 100101,Beijing; 2) 697A Institut für Chemie / Biochemie, Freie Universität Berlin, Takustr.6, Cut mediated transcriptional regulation of the COPII secretory pathway 14195 Berlin; 3) Charité-Universitätsmedizin Berlin, Charitéplatz directs class specific dendrite morphogenesis in Drosophila. Srividya 1,10117 Berlin. Chandramouli Iyer, Eswar P. R. Iyer, Ramakrishna Meduri, Madhu Karamsetty, Daniel N. Cox. Dept. of Molecular and 706A Microbiology, Krasnow Institute for Advanced Study, George Mason Drosophila adducin, encoded by hu-li tai shao, regulates Dlg through University, Fairfax, VA. PAR-1 and CaMKII dependent phosphorylation during neuromuscular junction development. Simon Wang1, Jing Yang2, Amy Tsai2, Charles 698B Krieger2, Nicholas Harden1. 1) Department of Molecular Biology and NMNAT protects against hypoxia-induced dendrite degeneration. Yuhui Biochemistry, Simon Fraser University, Burnaby, British Columbia, Wen, R. Grace Zhai, Michael D. Kim. Molecular and Cellular Canada; 2) Department of Biomedical Physiology and Kinesiology, Pharmacology, University of Miami, Miller School of Medicine, Miami, Simon Fraser University, Burnaby, British Columbia, Canada. FL. 707B 699C Maintenance of Neuronal Phenotype in the Adult Nervous System. Genetic control of dendrite pruning in Drosophila dendritic arborization Douglas Allan, Kevin Eade, Hailey Fancher. Cellular and neurons. Fengwei Yu1,2,3, Daniel Kirilly1, Ying Gu1,2, Edwin Lim1, Physiological Sciences, University of British Columbia, Vancouver, Zhuhao Wu4, Arash Bashirullah5, Boon Chuan Low2, Alex L. British Columbia, Canada. Kolodkin4, Hongyan Wang3,6. 1) Temasek Life Sciences Laboratory, Singapore, Singapore; 2) Department of Biological Sciences, National 708C University of Singapore, 14 Science Drive, Singapore 117543; 3) Cis-Regulatory Integration of Intrinsic Transcription Factors with Neuroscience and Behavioral Disorder Program, Duke-NUS Graduate Target-Derived Signals in Neuronal Differentiation. Anthony Berndt1, Medical School Singapore, 8 College Road, Singapore 169857; 4) Marc Ridyard1, Tianshun Lian1, Jonathan Tang2, Douglas Allan1. 1) Solomon H. Snyder Dept. of Neuroscience, Howard Hughes Medical Cellular & Physiological Sciences, University of British Columbia, Institute The Johns Hopkins School of Medicine, 725 N. Wolfe St., Vancouver, British Columbia, Canada; 2) Department of Molecular and Baltimore, MD 21205; 5) Division of Pharmaceutical Sciences, 777 Cellular Biology Harvard University 16 Divinity Ave. Cambridge, MA Highland Ave., University of Wisconsin, Madison, WI 53705; 6) 02138. Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597. 709A An RNAi-based Screen to Identify Transcription Factors Required for 700A the Development of the Wing Expansion Circuit in Drosophila. Isaac APC/CCdh1 mediated CNS neurodegeneration in Drosophila Dripps, Fengqiu Diao, Benjamin White. LMB, NIMH, NIH, melanogaster. Alexander Braun1,2, Rosa Mino1, Jermaine Lawson1, Bethesda, MD. Amandeep Kaur1, Israel Nnah1, Elena Kaplan1, Ivan J. Santiago1, Fejzije Bala1, Tadmiri Venkatesh1. 1) Department of Biology, City 710B College of New York, New York, NY 10031; 2) CUNY Graduate Subdivision of the neuroectoderm into discrete dorsal-ventral domains: Center, Biology PhD Program, New York, NY 10016. generated by a conserved mechanism? Francisco F. Esteves1, Erika Kague2, Shannon Fisher2, Ethan Bier1. 1) Dept Biological Sci, Univ 701B California, San Diego, La Jolla, CA; 2) Department of Cell and Study of Cell Lineage in Drosophila Retinal Basal Glia. Yu Fen Developmental Biology University of Pennsylvania, Philadelphia, PA Huang1,2, Y. Henry Sun1,2. 1) Institute of Molecular Biology, Academia 19104. Sinica, Taipei, Taiwan; 2) Department of Life Science and Institute of Genome Science, National Yang-Ming University, Taipei, Taiwan. 711C Epigenetic Regulation of Odorant Receptor Expression in the 702C Drosophila Olfactory System. Pelin C. Volkan1,2, Qingyun Li1. 1) Identification of new glial cell specific gene functions. Imke Schmidt, DEPARTMENT OF BIOLOGY, DUKE UNIVERSITY, DURHAM, Silke Thomas, Christian Klämbt. Institute for neurobiology, NC; 2) DUKE INSTITUTE FOR BRAIN SCIENCE, DUKE University of Münster, Münster, Nordrhein-Westfalen, Germany. UNIVERSITY, DURHAM, NC.

703A 712A Identification and Characterization of Downstream Effectors Mediating Robust specification of sensory neuron by dual function of Charlatan, a Cut Transcriptional Regulation of Class-Specific Dendrite Drosophila NRSF/REST-like repressor of extramacrochaetae and hairy. Morphogenesis via Global Functional Genomic Analyses. Eswar P. R. Yasutoyo Yamasaki, Young-Mi Lim, Leo Tsuda. National Center for Iyer, Srividya Chandramouli Iyer, Madhu Karamsetty, Daniel N. Geriatrics and Gerontology, Obu, Aichi, Japan. Cox. Dept. of Molecular and Microbiology, Krasnow Institute for Advanced Study, George Mason Univ, Fairfax, VA. 713B Pharmacogenetic regulation of acetylcholinesterase activity in 704B Drosophila reveals the regulatory mechanisms of AChE inhibitors in Drosophila acyl-CoA synthetase long-chain family member 4 regulates synaptic plasticity. Wontae Kim1,2, Daeweon Lee2, Jinkyu Choi2, axonal transport of synaptic vesicles and is required for synaptic Ayoung Kim2, Sangmi Han1, Kwanho Park1, Jiyoung Choi1, Jonggil development and transmission. Zhihua Liu, Yan Huang, Yi Zhang, Di Kim1, Youngcheol Choi1, Sihyeock Lee3, Youngho Koh2. 1) National Chen, Yong Q. Zhang. Institute of Genetics and Developmental Academy of Agricultural Science, Suwon, Korea; 2) Ilsong Institute of Biology, Chinese Academy of Sciences, Beijing, China. Life Science, Hallym University, Anyang, Korea; 3) Seoul National University, Seoul, Korea.

POSTER SESSIONS See page 16 for presentation schedule Poster board number is in bold above title. The first author is the presenter. Full abstracts can be found online at drosophila-conf.org

714C 724A Trophic actions of neuronal dopamine during the development of a Regulation of neural stem cell self-renewal and differentiation. serotonergic feeding circuit in Drosophila melanogaster. Wendi S. Hongyan Wang1,6, Kai Chen Chang2, Gisela Garcia-Alvarez1, Neckameyer, Parag Bhatt. Dept Pharmac & Physiol Sci, St Louis Univ Gregory Somers3, Rita Sousa-Nunes4, Fabrizio Rossi5, Cayetano School Med, St Louis, MO. Gonzalez5, William Chia2. 1) Duke-NUS Gradaute Medical School Singapore, Singapore, Singapore; 2) Temasek Life Sciences Laboratory, 715A 1 Research Link, Singapore 117604; 3) Department of Genetics, La Comparative analyses of the corazonin gene in dipteran insects. Kai Trobe Institute for Molecular Science (LIMS), La Trobe University, Vic Sha, Craig Conner, Dae Choi, Jae Park. University of tennessee - 3086 Australia; 4) National Institute for Medical Research, Mill Hill, Knoxville, BCMB, TN. London NW7 1AA, UK; 5) Cell Division Group, IRB-Barcelona, PCB, c/Baldiri Reixac 10-12, Barcelona, Spain; 6) Dept. of Physiology, Yong 716B Loo Lin School of Medicine, National University of Singapore, Drosophila FMRP regulates microtubule network formation and axonal Singapore 117597. transport of mitochondria. Ai Y. Yao1, Shan Jin1,2, Xin H. Li1, Zhi H. Liu1, Xue H. Ma1, Jing Tang1, Yong Q. Zhang1. 1) Institute of 725B Genetics and Developmental Biology, Chinese Academy of Sciences , Spatial fluctuation of Notch activity coordinates neuroepithelial stem Beijing, China; 2) Hubei University, Wuhan, Hubei, China. cell maintenance and differentiation. Mo Weng1,2, Jill Haenfler3, Cheng-Yu Lee1,2. 1) Cell & Dev Biol; 2) Ctr for Stem Cell Biol, Life 717C Sci Inst; 3) Cell & Mol Biol, Univ Michigan, Ann Arbor, MI. Regulation of neural stem cell fate in Drosophila cell death mutants. Richa Arya, Ying Tan, Megumu Yamada-Mabuchi, Kristin White. 726C CBRC, MGH/HARVARD, CHARLESTOWN, MA. Neuropeptide signaling regulates synaptic growth at Drosophila larval NMJ. Xu Chen, Barry Ganetzky. Laboratory of Genetics, University 718A of Wisconsin-Madison, MADISON, WI, 53706. Analysis of NOMPA domains required for connecting mechanosensory cilia to the dendritic cap. Jeongmi Lee, Yun Doo Chung. Department 727A of Life Science, University of Seoul, Seoul, Korea. Axonal transport is essential for proper synapse function and contributes to distal synaptic abnormalities seen in neurodegenerative disease. 719B Shermali D. Gunawardena1, Min J. Kang1, Monique Michiewicz1, Exploring the basis of neural enhancer sub-pattern specificity: Fine Tadeusz J. Kaczynski1, Samantha Fye1, Hong Bao2, Bing Zhang2, structure analysis of cis-regulatory sequences that control the late Shermali D. Gunawardena1. 1) Department of Biological Sciences, temporal network determinant castor. Mukta Kundu, Alexander The State University of New York at Buffalo, NY 14260; 2) Department Kuzin, Jermaine Ross, Thomas Brody, Ward F. Odenwald. Neural of Zoology, University of Oklahoma, Norman, OK 73019. Cell Fate Determinants, NINDS, Bethesda, MD. 728B 720C Mechanical force initiates the neuromuscular synapse. Tiffany Li1, Notch signaling regulates neuroepithelial stem cell maintenance and Wylie Ahmed2, Jie Sun1, Scott Siechen1, Franklin Carrero- neuroblast formation in Drosophila optic lobe development. Hong Luo, Martínez3, Taher Saif2, Akira Chiba1. 1) Biology, University of Wei Wang, Wenke Liu, Yue Wang, Liya Zhou, Xiaofang Tang. Miami, Coral Gables, FL; 2) Mechanical Science and Engineering, School of Life Sciences, Tsinghua University, Beijing, China. University of Illinois, Urbana, IL; 3) Biology, University of Puerto Rico, Mayagüez, Puerto Rico. 721A A role for Mbt in the proliferation of central brain neuroblasts. Juliane 729C Melzer, Thomas Raabe. University of Würzburg, Institut für spastin, which encodes a microtubule-severing protein, and Pak3, a Medizinische Strahlenkunde und Zellforschung, Würzburg, Germany. regulator of the actin cytoskeleton, genetically interact in synapse development. Emily F. Ozdowski, Nina T. Sherwood. Dept Biol, Duke 722B Univ, Durham, NC. Polycomb Complexes Restrict Drosophila Neuroblast Competence. Johnny Touma, Frank Weckerle, Sarah Min, Norma Cardona, Mike Cleary. Natural Sciences, University of California, Merced, Pattern Formation Merced, CA. 730A 723C Quantitative Analysis of Dorsal Ventral Patterning in Pre-blastula Control of Neural Lineage Topology by a Notch-mediated Genetic Crossveinless 2-/- Drosophila Embryos. Christina Brakken-Thal1,2, Switch in Neural Progenitor Division Mode. Carina Ulvklo, Ryan David Umulis3, Hans Othmer4, Michael O'Connor5. 1) Chemical MacDonald, Caroline Bivik, Magnus Baumgardt, Daniel Karlsson, Engineering, University of Minnesota, Minneapolis, MN; 2) MD/PhD Erika Lundin, Stefan Thor. Dept Molec Gen, Clin/Exper Med, Program, University of Minnesota, Minneapolis, MN; 3) Agricultural Linkoping Medical Sch, Linkoping, Sweden. and Biological Engineering, University of Purdue, West Lafayette, IN; 4) Department of Mathematics, University of Minnesota, Minneapolis, MN; 5) Genetics Cell Biology and Development, University of Minnesota, Minneapolis, MN.

731B A novel mutation affecting the patterning of the appendage primordia in the follicular epithelium. Mariana Fregoso Lomas. Biology, McGill University, Montreal, Canada.

POSTER SESSIONS See page 16 for presentation schedule Poster board number is in bold above title. The first author is the presenter. Full abstracts can be found online at drosophila-conf.org

732C 741C The formation of the Bicoid morphogen gradient requires protein defective proventriculus (dve), a new member of DV patterning in the movement from anteriorly localized mRNA. Shawn C. Little1, Gasper eye. Oorvashi Roy G. Puli1, Takeshi Yorimitsu3, Hideki Nakagoshi3, Tkacik2, Thomas Kneeland3, Eric F. Wieschaus1, Thomas Gregor3. Amit Singh1,2,4. 1) Department of Biology, University of Dayton,300 1) Department of Molecular Biology, Princeton UniversIty / HHMI, College Park Drive, Dayton, OH; 2) Premedical Program, University of Princeton, NJ; 2) Department of Physics and Astronomy, University of Dayton, 300 College Park Drive, Dayton,OH; 3) Graduate School of Pennsylvania, Philadelphia, PA; 3) Joseph Henry Laboratories of Natural Science and Technology, Okayama University, 3-1-1 Tsushima- Physics, Lewis-Sigler Institute for Integrative Genomics, Princeon naka, Kita-ku, Okayama 700-8530, Japan; 4) Center for Tissue University, Princeton, NJ. Regeneration and Engineering at Dayton (TREND), University of Dayton, Dayton, OH. 733A Genetic screens of mutants on the second and third chromosomes to 742A identify genes involved in the left-right asymmetric development of the Extramacrochaete Controls the Morphogenetic Furrow by Regulating embryonic gut in Drosophila. Mitsutoshi Nakamura1, Naotaka Hedgehog Signaling. Carrie M. Spratford, Justin P. Kumar. Biology, Nakazawa1, Kiichiro Taniguchi1, Reo Maeda1, Takashi Okumura1, Indiana University, Bloomington, IN. Ryo Hatori1, Akira Ishio1, Ayumi Ozaki1, Kenji Matsuno1,2. 1) Department of Biological Science and Technology, Tokyo University of 743B Science, Yamazaki, Noda, Chiba, Japan; 2) Reserch Institute for Science Genes patterning the R8 photoreceptor in the Drosophila retina. Ece and Technology, Tokyo University of Science. Terzioglu Kara, Arzu Öztürk, Arzu Celik. Department of Molecular Biyology and Genetics, Boaziçi University, Bebek, stanbul, Turkey. 734B Role of an E3 ubiquitin ligase in ventral eye development. Meghana 744C Tare1, Madhuri Kango-Singh1,2,3, Amit Singh1,2,3. 1) Department of Eya and So are Necessary for Maintaining Discrete Expression Patterns Biology, University of Dayton, 300 College Park Drive, Dayton OH; 2) of Selector Genes in the Developing Drosophila Eye. Bonnie Weasner, Premedical Program, University of Dayton, 300 College Park Drive, Justin Kumar. Dept Biol, Indiana Univ, Bloomington, IN. Dayton OH; 3) Center for Tissue Regeneration and Engineering at Dayton (TREND), University of Dayton, Dayton, OH. 745A The role of the zinc finger homeodomain-2 (zfh-2) gene in Drosophila 735C leg joint development. Ana Guarner1, Cristina Manjón2, Magali Genes in the leg patterning and planar polarity pathways regulate sex Suzanne3, Ernesto Sánchez-Herrero1. 1) Centro de Biología Molecular comb morphology and rotation. Joel Atallah, Setong Mavong, Gerard Severo Ochoa, Madrid, Madrid, Spain; 2) CMIMA building, Passeig Vurens, Seth Thompson, Alexa Mutti, Xiao Xie, Artyom Kopp. Marítim de la Barceloneta, 37-49 08003 Barcelona; 3) LBCMCP, UMR Evolution & Ecology, UC Davis, Davis, CA. 5088 CNRS - Université P. Sabatier TOULOUSE III.

736A 746B Drosophila histoblasts: one population many destinies. Carla Prat- Bristles as barriers to tissue elongation: the case of the rotating sex Rojo, Elena Rebollo, Enrique Martin-Blanco. IBMB-CSIC. PARC comb. Nicolas Malagon1, Joel Atallah2, Ellen Larsen1. 1) University CIENTIFIC DE BARCELONA, BARCELONA, Barcelona, Spain. of Toronto, Toronto, Canada; 2) Department of Evolution and Ecology , University of California - Davis, Davis, CA, USA. 737B Identification of Novel Enhancers Underlying Morphological Evolution 747C of the Drosophila Eggshell. Yang Gao, Igor Borodulin, Albert Erives. Identification of the gene responsible for the wings apart phenotype in Dept Biological Sciences, Dartmouth College, Hanover, NH. Drosophila melanogaster. Ginny Morriss, Carmelita Jaramillo, Richard Cripps. Biol, Univ New Mexico, Albuquerque, NM. 738C The retinal determination gene Dachshund controls the dynamics of cell 748A shape changes during the differentiation of the Drosophila eye. Developmental Stage Annotation of Drosophila Embryos. Lei Yuan1,3, Catarina Bras-Pereira1, Fernando Casares2, Florence Janody1. 1) Shuiwang Ji1,3, Jun Liu1,3, Charlotte Konikoff2,3, Timothy Karr2, Actin Dynamics Lab, Instituto Gulbenkian de Ciência, Oeiras, Portugal; Stuart Newfeld2, Sudhir Kumar2,3, Jieping Ye1,3. 1) Department of 2) Centro Andaluz de Biología del Desarrollo (CABD), UPO-CSIC-JA, Computer Science and Engineering, Arizona State University, Tempe, Sevilla, Spain. AZ; 2) School of Life Sciences, Arizona State University, Tempe, AZ; 3) Center for Evolutionary Medicine and Informatics, The Biodesign 739A Institute, Arizona State University, Tempe, AZ. Role of Centrosomin in Apical Domain Regulation during Drosophila Photoreceptor Morphogenesis. Geng Chen, Sang-Chul Nam. 749B Department of Biology, Baylor University, Waco, TX. Roles of SUMO in Hunchback and RAS function. Joseph H. Cao, Minghua Nie, Albert J. Courey. UCLA, Los Angeles, CA. 740B Role of Kinesin-heavy-chain in Crumbs localization along the 750C rhabdomere elongation in Drosophila photoreceptor. Garrett P. Identification of Ftz/Ftz-F1 Genomic Targets. Amanda Field1, Ray League, Sang-Chul Nam. Department of Biology, Baylor University, Anderson2, Leslie Pick1,2. 1) Program in Molecular & Cell Biology, Waco, TX. University of Maryland, College Park, MD; 2) Program in Cell Biology & Molecular Genetics, University of Maryland, College Park, MD.

751A Role of regulatory elements in the 3'UTR of the pair-rule gene eve in the robustness of patterning. Valerie Hilgers, Michael Levine. Department of Molecular and Cellular Biology, Division of Genetics, Genomics, and Development, University of California at Berkeley, Berkeley, California 94720, USA.

POSTER SESSIONS See page 16 for presentation schedule Poster board number is in bold above title. The first author is the presenter. Full abstracts can be found online at drosophila-conf.org

752B Gene expression noise in spatial patterning: hunchback promoter Physiology and Aging 1 structure affects noise amplitude and distribution. David M. Holloway , Francisco JP Lopes2, Alexander V. Spirov3. 1) Dept Mathematics, 761B British Col Inst Tech, Burnaby, BC, Canada; 2) Instituto de Biofisica, Analysis of miR-277 targets in Drosophila and its role for metabolism Universidade Federal do Rio de Janeiro, Brazil; 3) Computer Science and lifespan. Stephanie Esslinger, Klaus Förstemann. LMU Munich, and CEWIT, Stony Brook University, NY, USA. Gene Center , Munich, Germany.

753C 762C The Evolutionary and Developmental Dynamics of the Gap Gene The Effect of Resveratrol and Diet on Lifespan and Nutrient Storage. Network. Johannes Jaeger, Karl Wotton, Anton Crombach, Damjan Alexis A. Nagengast1,3, Charniece Knight2, Michael Polen3, Neha Cicin-Sain. EMBL/CRG Research Unit in Systems Biology, CRG - Sirohi2, Timothy Rudolph3, Hemlata Mistry2,3, Justin DiAngelo4. 1) Centre de Regulació Genòmica, Universitat Pompeu Fabra (UPF) Dr. Dept Biochemistry, Widener Univ, Chester, PA; 2) Dept of Biology, Aiguadër 88 08003 Barcelona, Spain. Widener University, Chester, PA; 3) Dept Chemistry, Widener University, Chester, PA; 4) Dept Biology, Hofstra University, 754A Hempstead, NY. New gene encoding histone chaperone-like protein interacts with spineless in the regulation of limbs morphogenesis in Drosophila 763A melanogaster. Olga Simonova1, Elena Modestova2, Julia Sir2 effects on longevity are modified by mitochondrial genotype and Vorontsova1, Olga Zatsepina3, Arsen Mikaelyan1, Mikhail diet. Chen-Tseh Zhu1, Marissa Holmbeck1, Eugenia Villa-Cuesta1, Slezinger1, Roman Cherezov1, Boris Kuzin1. 1) Koltsov Institute of Jason Wood2, Stephen Helfand2, David Rand1. 1) Department of Developmental Biology, RAS, Moscow, 119334 Russia; 2) Institute of Ecology and Evolutionary Biology, Brown University, Providence, RI; Gene Biology, RAS, Moscow, 119334 Russia; 3) Engelgardt Institute of 2) Department of Molecular, Cellular Biology Biochemistry, Brown Molecular Biology, RAS, Moscow, 119334 Russia. University, Providence, RI.

755B 764B Using variable expressivity in Drosophila segmentation to understand Drosophila Nuclear Receptor DHR4 determines timing of ecdysone the mechanisms of phenotypic stability. Alexander V. Spirov1, pulses by oscillating between nucleus and cytoplasm in a PTTH- Francisco JP Lopes2, David M. Holloway3. 1) CEWIT, State Univ dependent manner. Kirst King-Jones, Qiuxiang Ou, Adam Magico. New York, Stony Brook, NY; 2) Instituto de Biofisica, Universidade Dept Biological Sci, Univ Alberta, Edmonton, AB, Canada. Federal do Rio de Janeiro, Brazil; 3) Mathematics, British Columbia Institute of Technology, Burnaby; Biology, University of Victoria, BC, 765C Canada. Genome-wide Ecdysone Receptor binding sites through the Drosophila melanogaster lifecycle. Rebecca F. Spokony, Nicolas Negre, 756C Christopher D. Brown, Carolyn A. Morrison, Nicholas A. Bild, Jesse Analysis and modeling of segmentation gene expression in Drosophila Cohen, Jennifer Zieba, Sarah Suchy, Kevin P. White. IGSB, Univ Kruppel mutants. Svetlana Surkova1, Konstantin Kozlov1, Lena Chicago, Chicago, IL. Panok2, Maria Samsonova1, John Reinitz2. 1) Department of Computational Biology, State Polytechnical University, St Petersburg, 766A Russia; 2) Department of Statistics, University of Chicago, IL, USA. Juvenile hormone regulation of lipid and carbohydrate metabolism in adult Drosophila. Hua Bai, Rochele Yamamoto, Stephanie Vasquez, 757A Marc Tatar. Department of Ecology and Evolutionary Biology, Brown STAT is an essential activator of the zygotic genome in the early University, Providence, RI. Drosophila embryo. Amy Tsurumi1, Fan Xia2, Jinghong Li3, Kimberly Larson1, Russell LaFrance1, Willis X. Li1. 1) Biomedical 767B Genetics, Univ. Rochester Med. Center, Rochester, NY; 2) Department The nuclear receptor dHNF4 is required for the maintenance of glycogen of Molecular Biology, Massachusetts General Hospital, Boston, MA; 3) stores during metamorphosis. William E. Barry, Jason M. Tennessen, Department of Medicine, University of California at San Diego, La Carl S. Thummel. Department of Human Genetics, University of Utah Jolla, CA. School of Medicine, Salt Lake City, UT.

758B 768C Inwardly Rectifying K+ channel Irk2 contributes to wing development Adult flies lacking dAMPK exhibit minor metabolic phenotypes. in Drosophila through interactions with the Dpp pathway. Emily A. Michelle L. Bland, Morris Birnbaum. Department of Medicine, Bates1, Giri Raj Dahal1, Joel Rawson2, Brandon Gassaway1, Ben University of Pennsylvania, Philadelphia, PA. Kwok1, Abigail Gehrett1, John Morrell1, Louis Ptácek3, Emily Bates1. 1) Chemistry and Biochemistry, Brigham Young University, 769A Provo, UT; 2) University of Texas Health Science Center, San Antonio, The mitochondrial protein CG14290 is required for carbohydrate TX; 3) HHMI, University of California, San Francisco, CA. homeostasis in Drosophila melanogaster. Daniel K. Bricker1, Thomas Orsak2, Yu-Chan Chen2, Jared Rutter2, Carl S. Thummel1. 1) 759C Department of Human Genetics, University of Utah, Salt Lake City, UT; The vein organizing activities of abrupt and knirps in Drosophila wing. 2) Deptartment of Biochemistry, University of Utah, Salt Lake City, UT. Orna Cook, Ethan Bier. Dept. of Biology, UCSD, San Diego, CA. 770B 760A A frequency- and density-dependent gene that orchestrates dispersive Body-wall cell fate in the Drosophila thorax is initiated by Dpp and behavior in Drosophila is a modifier of sensory signaling pathways. propagated by a positive feedback loop involving the Egfr-ligand Vein. Maria Capovilla1, Laury Arthaud2, Selim Ben Rokia-Mille2, Hussein Amanda A. Simcox, Litty Pail, Sathiya Manivannan, Shu-Huei Raad2, Aviv Dombrovsky3, Nicolas Prevost2, Alain Robichon2. 1) Wang, Liana Bonanno, Christina Austin, Sarah Lewis. Molec Gen, Dulbecco Telethon Institute, Dept. of Biology and Evolution, University Ohio State Univ, Columbus, OH. of Ferrara, Ferrara, Italy; 2) UMR INRA/CNRS/UNSA 6243, University of Nice- Sophia Antipolis, Sophia-Antipolis, France; 3) Agricultural Research Organization, the Volcani Center, Israel. 73

POSTER SESSIONS See page 16 for presentation schedule Poster board number is in bold above title. The first author is the presenter. Full abstracts can be found online at drosophila-conf.org

771C 782B Drosophila lipophorin receptors mediate the uptake of neutral lipids in Teaching Old Brains New Tricks: Insulin Signaling, Autophagy and oocytes and imaginal disc cells by an endocytosis-independent Neural Regeneration. Kim Finley1,2, Bryan Bartlett1,2, Roxanne mechanism. Joaquim Culi, Esmeralda Parra-Peralbo. Centro Andaluz Kotzebue1,2, Heriberto Sanchez1, Katia Suarez1, Arysa Gonzalez1, de Biología del Desarrollo (CSIC-UPO), Sevilla, Spain. Aubrey Sever1, Anne Simonsen3. 1) BioScience Center, San Diego State University, San Diego, CA; 2) Department of Biology, San Diego 772A State University, San Diego, CA; 3) Department of Biochemistry, Activation of the innate immune system in the adult fat body promotes University of Oslo, 0317 Oslo, Norway. triglyceride storage. Melody Esmaeili, Michelle Bland, Morris Birnbaum. Department of Medicine, University of Pennsylvania, 783C Philadelphia, PA. A Genetic Screen to Identify the Mechanism of General Anesthetics. Paniz Heidari1,4, Seth M. Judd1,4, Adam G. Dawson1, Krista 773B Pearman2, Michael J. Murray3, Gerald B. Call2. 1) Arizona College Rapid effects of dietary restriction in Drosophila through gustatory of Osteopathic Medicine (AZCOM), Midwestern University, Glendale, perception and nitric oxide synthase. Nancy J. Linford1, Tammy P. AZ; 2) Department of Pharmacology, AZCOM, Midwestern University, Chan1,2, Scott D. Pletcher1,2. 1) Molecular and Integrative Physiology, Glendale, AZ; 3) Department of Anesthesiology, Mayo Clinic, University of Michigan, Ann Arbor, MI; 2) Developmental Biology Scottsdale, AZ; 4) Co-first authors. Program, Baylor College of Medicine, Houston, TX. 784A 774C Pheromone production and perception modulate lifespan and sexual Temporal synchronization of O-GlcNAc post-translational modification attractiveness in Drosophila through mechanisms involving insulin in Drosophila melanogaster as a function of circadian rhythm. Amanda signaling. Tsung-Han Kuo1, Joanne Yew2,3, Tatyana Fedina4, Klaus C. Zirzow, Dona C. Love, John A. Hanover. Laboratory of Cell Dreisewerd2, Herman Dierick1, Edward Kravitz3, Scott Pletcher1,4. Biochemistry and Biology, NIDDK/NIH, Bethesda, MD. 1) Molecular & Human Genetics, Baylor College Medicine, Houston, TX, USA; 2) Department of Medical Physics and Biophysics, University 775A of Muenster, Muenster, Germany; 3) Department of Neurobiology, Reliability and precision of Drosophila feeding assays. Ariadna Harvard Medical School, Boston, MA, USA; 4) Geriatrics Center, Amador, Angela Phillips, William Ja. The Scripps Research Institute, University of Michigan, Ann Arbor, MI, USA. Department of Metabolism and Aging, 30 Scripps Way 3B3, Jupiter, FL. 785B 776B The Drosophila homologue of the human multidrug resistance- Investigating the Role of Nutrition and Insulin Signaling on Autophagy associated protein 4 (dMRP4) protects animals against oxidative stress and Neuronal Aging. Roxanne Kotzebue1,2, Bryan Bartlett1,2, Arysa by modulating ROS accumulation. He Huang1, Ying Lu-Bo1, Gabriel Gonzalez1, Aubrey Sever1, Katia Suarez1, Kim Finley1,2. 1) Haddad11,2. 1) Department of Pediatrics, School of Medicine, UCSD, BioScience Center, San Diego State University, San Diego, CA; 2) La Jolla, CA; 2) the Rady Children’s Hospital of San Diego, 9500 Department of Biology, San Diego State University, San Diego, CA. Gilman Drive 0735, La Jolla, CA 92093-0735, USA.

777C 786C Food protein-carbohydrate manipulation and its effect on fruit fly A myeloperoxidase like protein in Drosophila melanogaster. Sanjay growth and development. Amber Rico1,2, Spencer T. Behmer2, Aaron Nag, Atanu Duttaroy. Dept Biol, Howard Univ, Washington, DC. Tarone2. 1) Department of Biology, Ripon College, Ripon, WI; 2) Department of Entomology, Texas A&M University, College Station, 787A TX. Neuronal synaptobrevin functions in neuronal maintenance independent of its role in neurotransmitter release. Adam S. Haberman1, Daniel 778A Epstein1, W. Ryan Williamson1, Ian A. Meinertzhagen2, P. Robin tRNA(iMet) Synthesis Promotes Growth and Development in Hiesinger1. 1) Dept. of Physiology, UT Southwestern Med Cntr, Dallas, Drosophila. Elizabeth J. Rideout, Savraj S. Grewal. Clark H. Smith TX; 2) Dept. of Psychology, Dalhousie University, Halifax, Nova Brain Tumour Centre, Dept. Biochemistry and Molecular Biology, Scotia. University of Calgary, Calgary, AB, Canada. 788B 779B Identification and characterization of genes encoding peritrophic matrix Larval diet manipulation affects transition into the adult stage in proteins. Lacey Harbour, Nona Amiri, Gae Kovalick. Biology, Univ Drosophila melanogaster. Madelyn Weeks1,2, Aaron Tarone2, Spencer Texas Permian Basin, Odessa, TX. T. Behmer2. 1) Department of Biochemistry & Genetics, Clemson University, Clemson, SC; 2) Department of Entomology, Texas A&M 789C University, College Station, TX. Immunosenescence in the Drosophila Malpighian tubule. Ana M. Hernandez. Department of Ecology and Evolutionary biology, Brown 780C University, Providence, RI. A Genetic Screen Identifies Wnt Signaling Involving Juvenile Hormone Action. Mohamed A. Abdou, Cheng Peng, Jianhua Huang, Ola 790A Zyaan, Jian Wang. Department of Entomology University of Maryland ILK/Integrin function in organismal and cardiac aging in Drosophila. at College Park College Park, MD 20742. Mayuko Nishimura, Malene Hansen, Karen Ocorr, Rolf Bodmer. Sanford-Burnham Medical Research Institute, La Jolla, CA. 781A In the fly brain vacuolization occurs progressively as a function of age 791B but is not associated with brain cell loss. Kristopher Beckwith1, Eva Intracellular recordings from cardiomyocytes reveal early Polston2, Atanu Duttaroy3. 1) Dept Human Genetics, Howard Univ, afterdepolarization events in both seizure and KCNQ channel mutants. Washington, DC; 2) Dept. of Physiology and Biophysics, Howard Yoav Nudell, John Perkowski, H.-S. Vincent Chen, Karen Ocorr. University College of Medicine, Washington, D.C; 3) Howard Development & Aging, Sanford-Burnham Medical Research Institute, University Department of Biology, Washington, D.C. La Jolla, CA.

POSTER SESSIONS See page 16 for presentation schedule Poster board number is in bold above title. The first author is the presenter. Full abstracts can be found online at drosophila-conf.org

792C 801C Changes in cuticular lipids, water loss and desiccation resistance in a Characterization of Zelda binding sites. Chung-Yi Nien1, Hsiao-Lan tropical drosophilid: Analysis of within population variation. Bhawna Liang1, Tenzin Gocha1, Sheng-Bo Fu1, Steve Butcher2, Hsiao-Yun Kalra1,, Ravi Parkash2, Dau Dayal2. 1) Department of biology, Liu1, John Manak2, Nikolai Kirov1, Chris Rushlow1. 1) New York University of Haifa, Tivon 36006 , Israel; 2) Department of genetics, University, 100 Washington Sq. East, New York, NY, 10003; 2) Dept of MD University, Rohtak 124001, India. Biology and the Roy J Carver Center for Genomics, 459 Biology Building, Univ of Iowa, Iowa City, IA 52242. 793A P-element screen to characterize the multiple dimensions of cold 802A tolerance in Drosophila melanogaster. Robert L. Kobey, Rob Gassert, Retinal determination factor Eyeless and type I bHLH Daughterless Kristi L. Montooth. Department of Biology, Indiana University, synergistically induce atonal expression and retina development. Miho Bloomington, IN. Tanaka-Matakatsu, Wei Du. Ben May Dept Cancer Res, The Univ Chicago, Chicago, IL. 794B Reduced expression of ribose-5-phosphate isomerase in neurons 803B tolerates oxidative stress, enhances lifespan, and attenuates Genetic analyses of CDK8-CycC functions in vivo. Qun Wang, Lauren polyglutamine toxicity in Drosophila. Horng-Dar Wang1,2, Ching-Tzu Bridges, Larry Jiang, Jun-Yuan Ji. Department of Molecular and Wang1, Yi-Yun Wang1, Ming-Hao Huang1, Tzu-Kang Sang1,2, Yi- Cellular Medicine, Texas A&M Health Science Center, College Station, Chun Chen1, Si-Chih Cho1, Chiou-Hwa Yuh3, Chao-Yung Wang4, TX. Theodore Brummel5. 1) Institute of Biotechnology, Natl Tsing Hua Univ, Hsinchu, Taiwan; 2) Department of Life Science, Natl Tsing Hua 804C Univ, Hsinchu, Taiwan; 3) Division of Molecular and Genomic A genome wide survey of DNA binding and dimeric partner specificities Medicine, National Health Research Institutes, Zhunan Town, Miaoli for Drosophila basic Helix-Loop-Helix Transcription Factors. Matthew County, Taiwan; 4) Second Section of Cardiology, Department of Basciotta, Jessie Brasefield, Scot Wolfe, Michael Brodsky. University Internal Medicine, Chang Gung Memorial Hospital at Linkou, Chang of Massachusetts Medical School, Worcester, MA. Gung University College of Medicine, Taoyuan, Taiwan; 5) Department of Biology, Long Island University, Brookville, NY 11548, U.S.A. 805A Characterization of the Function of cropped in Drosophila Eye Development. Yiyun Chen, Bryce Daines, Yumei Li, Rui Chen. Regulation of Gene Expression Human Genome Sequencing Center, Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, TX. 795C Evolutionary conservation of 5'-UTR mediated post-transcriptional 806B expression control in the Drosophila splicing assembly factor RNP-4F. Identification of nuclear receptor DHR96 target genes and DNA binding Jing Chen, G. Girija Lakshmi, Julie T. Yang, Gabriel P. Jones, sites in Drosophila. Niloofar Farboodi, Emma Nally, Qiuxiang Ou, Roshni Parikh, Shuxia Yi, Jack C. Vaughn. Dept Zoology, Miami Kirst King-Jones. Department of Biological Sciences, University of Univ, Oxford, OH. Alberta, Edmonton, AB, Canada.

796A 807C Psi is required for Histone H3 Acetylation and control of dmyc fliH, a novel cis-regulatory mutation in Drosophila wupA gene leads to transcription. Nicola J. Cranna1, Amanda Lee Jue Er1, Naomi indirect flight muscle hypercontraction. Hena Firdaus, Mohan J., Mitchell1, Zuquin Nie2, Hye Jung Chung2, David Levens2, Ross Arathi B.P., Upendra Nongthomba. MRDG Department, Indian Hannan3, Leonie Quinn1. 1) University of Melbourne, Parkville, VIC Institute of Science, Bangalore, India. Australia; 2) National Cancer Institute, Bethesda, Maryland, United States; 3) Peter MacCallum Cancer Centre, Melbourne, VIC, Australia. 808A Identification of cis-regulatory elements in the dmyc gene of Drosophila 797B melanogaster. Jasmine Kharazmi1, Cameron Moshfegh2. 1) Molec Genome-wide Transcription Factor Binding Varies with Gene Dosage in Biol Lab, Biotech Ctr Zurich, Zurich, Switzerland; 2) Material Sciences vivo. Matthew Davis1, Michael Eisen1,2. 1) UC Berkeley, Berkeley, Dept, ETHZ Zurich, Switzerland. CA; 2) Howard Hughes Medical Institute. 809B 798C A model for the regulation of tailless by three maternal signals in the ZLD binds to broad spectrum of zygotic genes prior to their early embryo. Yoosik Kim1, Kate M. Fitzgerald1, Gerardo Jiménez2, transcription. Xiao-Yong Li1, Milissa Harrison2, Tommy Kaplan2, Stanislav Y. Shvartsman1. 1) Department of Chemical Engineering and Michael Botchan2, Michael Eisen1,2. 1) Howard Hughes Medical Lewis-Sigler Institute for Integrative Genomics, Princeton University, Institute, University of California, Berkeley, CA; 2) Department of Princeton, NJ 08544, USA; 2) Institut de Biologia Molecular de Molecular and Cell Biology, California Institute of Quantitative Barcelona-CSIC and Institució Catalana de Recerca i Estudis Avançats, Biosciences, University of California, Berkeley, CA. Parc Científic de Barcelona, Barcelona 08028, Spain.

799A 810C Zelda coordinates gene regulatory networks in the early embryos. Importance of Pol II pausing for transcriptional precision during Hsiao-Lan Liang1, Chung-Yi Nien1, Sheng-Bo Fu1, Steve Butcher2, development. Mounia Lagha, Jacques Bothma, Emilia Esposito, Nikolai Kirov1, John Manak2, Chris Rushlow1. 1) Biology, New York Michael Perry, Vivek Chopra, Chiahao Tsui, Michael Levine. Univ, New York, NY; 2) Dept of Biology and the Roy J Carver Center Molecular and Cellular Biology, UC Berkeley, Berkeley, CA. for Genomics, 459 Biology Building, Univ of Iowa, Iowa City, IA 52242.

800B Sexually dimorphic expression of Flavin-containing Monooxygenase-2 in Drosophila melanogaster is directly regulated by Doublesex. Dion Luo. HHMI: Janelia Farm Research Campus, Ashburn, VA. 75

POSTER SESSIONS See page 16 for presentation schedule Poster board number is in bold above title. The first author is the presenter. Full abstracts can be found online at drosophila-conf.org

811A 822C Elucidating Regulatory Variation in cis, trans, and more within a Mapping cis-regulatory elements involved in the xenobiotic-induced population of D.simulans. Bradley J. Main1, Rita M. Graze2, Lauren expression of the Cyp6a8 gene of Drosophila melanogaster. Olivia Hill, M. McIntyre2, Marta L. Wayne2, Hyo-sik Jang1, Sergey V. Ganguly Ranjan. Biochem. Cellular & Mol. Biol, University of Nuzhdin1. 1) MCB, Univ Southern California, Los Angeles, CA; 2) Tennessee, Knoxville, TN. University of Florida,Gainesville,. 823A 812B Context dependent regulation of the Notch target argos. Ben Housden, Genome-wide analysis reveals that the FoxA protein Fkh plays a major Fred Bernard, Sarah Bray. Univ Cambridge, Cambridge, United role in maintaining salivary gland fate and function. Rika Maruyama, Kingdom. Elizabeth Grevengoed, Peter Stempniewicz, Deborah Andrew. Dept Cell Biol, Johns Hopkins Sch Med, Baltimore, MD. 824B Differential integration of DPax2 by abdominal and thoracic Hox 813C complexes generates cell-type specific pattern differences in gene Non-classical regulation of transcription: transvection at the Malic expression during embryogenesis. David Li-Kroeger1, Brian enzyme locus in Drosophila melanogaster. Thomas J. S. Merritt, Gebelein2. 1) Univ. of Cincinnati Mol. Dev. Biol. Graduate Program, Thomas E. C. H. Lum. Dept Chemistry & Biochem, Laurentian Univ, Cincinnati, OH; 2) Div. of Dev. Biol., Cincinnati Children's Hosp., Sudbury, ON, Canada. Cincinnati, OH.

814A 825C Regulation of gene expression in primary spermatocytes by meiotic Functional Diversification of Su(H) Binding Sites in the Regulation of arrest genes by positive and negative factors. Helen White-Cooper1, Su(H) Autoactivation During Drosophila External Sensory Organ Jianqiao Jiang1, Karen Doggett2. 1) Sch Biosci, Cardiff Univ, Cardiff, Development. Feng Liu, James Posakony. Dept Cell & Dev Biol, Univ United Kingdom; 2) Peter MacCallum Cancer Centre St. Andrews Place California, San Diego, La Jolla, CA. East Melbourne 3121. 826A 815B Functional and evolutionary implications of modularity in gene Computational discovery of cis-regulatory elements in Drosophila regulatory sequences. Tara L. Martin, Meghan Bragdon, Kelly embryogenesis. Manonmani Arunachalam1,2, Karthik Jayasurya1, Eckenrode, Angela DePace. Department of Systems Biology, Harvard Pavel Tomancak2, Uwe Ohler1. 1) Institute for Genome Sciences & Medical School, Boston, MA. Policy, Duke University, Durham, NC; 2) Max Planck Institute for Molecular Cell Biology and Genetics, Dresden, Germany. 827B Identifying the oenocyte enhancer of seven-up in Drosophila 816C melanogaster. Grace A. Mason, Kathryn M. Ryan, Richard M. Regulatory DNA of the engrailed and invected genes. Yuzhong Cheng, Cripps. Biology, University of New Mexico, Albuquerque, NM. Alayne Brown, Stefanie Kremer, Sarah Devido, Catherine Stefaniuk, Judith Kassis. Program in Genomics of Differentiation, 828C NICHD, Bethesda, MD. Functional Validation of Genome-wide Enhancer Predictions in Drosophila. Steven Miller1, Nicholas Nègre2, Chris Bristow3, Jia 817A Chen2, Rachel Sealfon3, Lijia Ma2, Manolis Kellis3, Kevin White2, Dissecting the Functionality of an Enhancer Family. Kurt M. James Posakony1. 1) Div. of Bio. Sci./CDB, UCSD, La Jolla, CA; 2) Dahlstrom, Niranjana Nataraja, Albert Erives. Dept. Biological Inst. for Genomics & Sys. Bio., Dept. of Human Genetics, The Univ. of Sciences. Dartmouth College, Hanover, NH. Chicago, Chicago, IL; 3) Comp. Sci. and A. I. Lab., Broad Institute of MIT and Harvard, Cambridge, MA. 818B From morphogens to morphogenesis: cis- regulatory logic in epithelial 829A patterning. Alisa Fuchs1, Enrica Charbonnier1,2, Giorgos Decoding the transcriptional program of epidermal differentiation. Pyrowolakis1,2. 1) Developmental Biology, University of Freiburg, Francois Payre1,5, Delphine Menoret1,5, Marc Santolini3, Isabelle Institute of Biology I, Freiburg, Germany; 2) Centre for Biological Fernandes1,5, Jennifer Zanet1,5, Yvan Latapie1,5, Piere Ferrer1,5, Signalling Studies (BIOSS), University of Freiburg, Freiburg, Germany. Herve Rouault3, Ignacio Gonzalez4, Philippe Besse4, Vincent Hakim3, Stein Aerts2, Serge Plaza1,5. 1) Centre de Biologie du 819C Developpement, University of Toulouse, UPS, Toulouse, France; 2) Transcriptional control and evolution of the patterning gene knirps in the Laboratory of Computational Biology, KU Leuven, Belgium; 3) second wing vein (L2) of Drosophila melanogaster. Valentino M. Laboratoire de Physique Statistique, ENS, Paris, France; 4) Institut de Gantz, Ethan Bier. Biological Sciences, University of California San Mathematique de Toulouse, France; 5) CNRS UMR5547, Toulouse, Diego, La Jolla, CA. France.

820A 830B Exploring Abdominal B expression in the accessory gland using BACs. Shadow enhancers provide robustness of gene expression in Drosophila Dragan Gligorov, Robert Maeda, François Karch. Zoology & patterning and development. Michael Perry1, Alistair Boettiger2, Animal Biol, Univ Geneva, Geneva, Switzerland. Jacques Bothma2, Mike Levine3. 1) Department of Integrative Biology, UC Berkeley, Berkeley, CA; 2) Biophysics Graduate Group, UC 821B Berkeley, Berkeley, CA; 3) Center for Integrative Genomics, Division of REDfly: The Regulatory Element Database for Drosophila, v3.0. Marc Genetics, Genomics, and Development, Department of Molecular and S. Halfon1,2,3, Steven M. Gallo1,2, Dave T. Gerrard4, David Miner2, Cell Biology, UC Berkeley. Michael Simich3, Benjamin Des Soye3, Casey M. Bergman4. 1) Department of Biochemistry, SUNY at Buffalo, Buffalo, NY; 2) NYS Center of Excellence in Bioinformatics & Life Sciences, Buffalo, NY; 3) Department of Biological Sciences, SUNY at Buffalo, Buffalo, NY; 4) Faculty of Life Sciences, University of Manchester, Manchester, UK.

POSTER SESSIONS See page 16 for presentation schedule Poster board number is in bold above title. The first author is the presenter. Full abstracts can be found online at drosophila-conf.org

831C 840C Comparative and functional analysis of doublesex cis-regulatory Evolution of Transcriptional Regulation in Early Embryos of the elements. Gavin Rice1, Michelle Arbeitman2. 1) Evolution and Drosophila Genus. Mathilde Paris1, Tommy Kaplan1, Xiao-Yong Li2, Ecology Dept, University of California at Davis, Davis, CA; 2) Robert K. Bradley1, Mark D. Biggin3, Michael Eisen1,2. 1) Molecular Molecular & Computational Biology Dept, University of Southern and Cellular Biology, QB3 Institute, BERKELEY, CA; 2) Howard California, Los Angeles, CA. Hughes Medical Institute, University of California Berkeley, Berkeley, CA; 3) Genomics Division, Lawrence Berkeley National Lab, Berkeley, 832A CA. Dissecting the cis-regulatory enhancers that control pdm-1 and pdm-2 neuroblast gene expression. Jermaine Ross1,2, Thomas Brody1, Mukta 841A Kundu1, Alexander Kuzin1, Ward F. Odenwald1. 1) Neural Cell-Fate Global Patterns of Gene Expression in the maleless mutant. Abhijit Determinants Section, NINDS, NIH; 2) Brown University. Sanyal, Lin Sun, Weiwu Xie, James Birchler. Division of Biological Sciences, University of Missouri, Columbia, MO. 833B Measuring the gene regulatory function of a metazoan cis-regulatory 842B module. Max V. Staller, Angela DePace. Systems Biology, Harvard Distinct mechanisms of short- and long-range repressors in the Medical School, Boston, MA. Drosophila embryo. David N. Arnosti1,2, Kurtulus Kok2, Sandhya Payankaulam1, Li M. Li3. 1) Dept Biochemistry and Molecular 834C Biology, Michigan State Univ, East Lansing, MI; 2) Program in Temporal regulation of Bicoid-dependent cis-regulatory elements by Genetics, Michigan State University; 3) Dept Microbiology and Zelda. Zhe Xu, Hongtao Chen, Jerry Huang, Steve Small. Biology, Molecular Genetics, Michigan State University. New York University, New York, NY. 843C 835A Visualizing and Quantifying Transcriptional Repression in the early Regulation of Mesodermal Gene Expression by Drosophila Cell Type- Drosophila embryo. Jacques Bothma, Joe Magliocco, Michael Levine. Specific Forkhead Transcription Factors. Xianmin Zhu1,2, Shaad M. UC Berkeley, Berkeley, CA. Ahmad1,2, Brian W. Busser1, Neal Jeffries1, Adrian Haimovich1, Alan M. Michelson1. 1) NIH / NHLBI, Bethesda, MD; 2) These authors 844A contributed equally to this work. Characterizing Functions of the Groucho Central Domains in Transcriptional Repression. Pak Kwong1, Wiam Turki-Judeh2, Albert 836B Courey1,2. 1) Department of Chemistry and Biochemistry, UCLA; 2) Global Analysis of Alternative Splicing in Drosophila. B. R. Graveley1, Molecular Biology Interdepartmental Program, UCLA. A. N. Brooks2, L. Yang1, G. May1, M. Duff1, J. Landolin3, K. Wan3, S. Dudoit2, S. Brenner2, S. Celniker3. 1) Genetics and Developmental 845B Biology, University of Connecticut Health Center, Farmington, CT; 2) miR-10 recognize target sequences of 3'UTR of Scr in D. melanogaster. University of California, Berkeley, CA; 3) Lawrence Berkeley National Jannet E. Salinas-Hernandez, J. C. Moreno, A. Esparza, S. Laboratory, Berkeley CA. Elizondo, D. Resendez. Biologia Celular y Genetica, Universidad Autonoma de Nuevo Leon, Monterrey, Nuevo Leon, Mexico. 837C Juvenile hormone modulates ecdysteroid-inducible transcription in the 846C larval salivary gland via the bHLH-PAS protein, Methoprene tolerant Cis-regulatory analysis of the snail locus demonstrate two early (MET). Vincent C. Henrich, Jenna L. Callender, Jesse Plotkin, embryonic enhancers share repressors. Angelike Stathopoulos, Leslie Joshua Beatty. CBGHR, Univ North Carolina at Greensboro, Dunipace, Anil Ozdemir. Div Biol, MC 114-96, Caltech, Pasadena, Greensboro, NC. CA.

838A 847A Quantitative Models of the Mechanisms that Control Genome-Wide Investigating mechanisms of transcriptional repression: Insights from Patterns of Transcription Factor Binding During Early Drosophila Brinker. Priyanka Upadhyai, Gerard Campbell. Biological Sciences, Development. Tommy Kaplan1, Xiao-Yong Li2, Peter Sabo3, Sean University of Pittsburgh, Pittsburgh, PA. Thomas3, John Stamatoyannopoulos3, Mark Biggin4, Michael Eisen1,2,4. 1) MCB/QB3, UC Berkeley, Berkeley, CA; 2) HHMI, UC 848B Berkeley, Berkeley, CA; 3) Genome Sciences, U of Washington, Seattle, Dynamics and Mechanisms of Yan Chromatin Association. Jemma L. WA; 4) Genomics Division, LBNL, Berkeley, CA. Webber, Jie Zhang, Ilaria Rebay. Ben May Department for Cancer Research, University of Chicago, Chicago, IL. 839B Cascading network responses to deficiencies in Drosophila melanogaster. John H. Malone1, DongYeon Cho2, Nicolas R. RNA Biology 1 1 3 2 Mattiuzzo , Renhua Li , Justen Andrews , Teresa Przytycka , Brian Oliver1. 1) Laboratory of Cellular and Developmental Biology, National 849C Institute of Diabetes, Digestive, and Kidney Diseases, National Institutes MicroRNAs Facilitate Evolutionary Canalization. Justin J. Cassidy1,2, of Health, Bethesda, Maryland, 20892 USA; 2) National Center for Richard W. Carthew1,2. 1) Department of Molecular Biosciences, Biotechnology Information, National Library of Medicine, National Northwestern University, Evanston, IL; 2) Chicago Center for Systems Institutes of Health, Computational Biology Branch, Bethesda, MD Biology. 20894; 3) Department of Biology, Indiana University, Bloomington, IN 47405. 850A Drosophila let-7-C is a direct target of the nuclear hormone receptor EcR. Geetanjali Chawla, Nicholas S. Sokol. Department of Biology, Indiana University, Bloomington, IN.

POSTER SESSIONS See page 16 for presentation schedule Poster board number is in bold above title. The first author is the presenter. Full abstracts can be found online at drosophila-conf.org

851B 861C The small RNA landscapes of 4 Drosophila cell lines. Delphine Systematic analysis of RNA-protein interactions in Drosophila. John D. Fagegaltier, Chenghai Xue, Alex Dobin, Thomas Gingeras, The Laver1, Karen Fung2, Sachdev Sidhu1, Craig Smibert1,2, Howard ModEncode Fly Transcriptome Group. Cold Spring Harbor Lipshitz1. 1) Department of Molecular Genetics, University of Toronto, Laboratory, Cold Spring Harbor, NY. Toronto, Canada; 2) Department of Biochemistry, University of Toronto, Toronto, Canada. 852C miR-275 is indispensable for blood digestion and egg development in 862A the mosquito Aedes aegypti. Alexander Raikhel, Bart Bryant, Warren RNA-mediated tissue-specific regulation of the gypsy chromatin MacDonald. Univeristy of California , Riverside, CA. insulator. Leah H. Matzat, Ryan K. Dale, Nellie Moshkovich, Elissa P. Lei. Laboratory of Cellular and Developmental Biology, National 853A Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, The microRNA miR-8 regulates adult abdominal cuticle pigmentation. 20892. Iryna Shakhmantsir, Evan J. Waldron, Jennifer A. Kennell. Biology, Vassar College, Poughkeepsie, NY. 863B Analysis of tissue-specific requirements for the nonsense mediated 854B mRNA decay pathway. Alex Chapin, Mark M. Metzstein. Human Identification and characterisation of more than 1000 non-coding Gen, Univ Utah, Salt Lake City, UT. transcripts in Drosophila. Andrew Roger Bassett, Robert Young, Charlotte Tibbit, Ji-Long Liu, Chris Ponting. MRC Functional 864C Genomics Unit, University of Oxford, Oxford, Oxfordshire, United Analysis of target features and genes necessary for nonsense mediated Kingdom. decay. Kimberly A. Frizzell, Shawn Rynearson, Mark M. Metzstein. Dept Human Genetics, Univ Utah, Salt Lake City, UT. 855C Drosophila Transcriptome RNA-Seq Data Identifies Candidate RNA 865A Editing Sites in 561 Additional Genes. Joseph W. Carlson1, Brenton Screens for novel factors and required targets of nonsense mediated R. Gravely2, Peter Cherbas3, Susan E. Celniker1, modENCODE mRNA decay. Jonathan O. Nelson, Mark M. Metzstein. Dept Human Drosophila Transcriptome Project. 1) Lawrence Berkeley National Genetics, Univ Utah, Salt Lake City, UT. Laboratory, Berkeley CA; 2) University of Connecticut Health Center, Framington CT; 3) Indiana University, Bloomington IN. 866B Identification of cell type-specific mRNA decay networks in Drosophila. 856A Maxine Umeh, Mike Cleary. School of Natural Sciences, University of Functional analysis of Drosophila eIF4E in P bodies. Paola Ferrero1,2, California, Merced, Merced, CA. Carla Layana1,2, Ezequiel Paulucci1, Rolando Rivera Pomar1,2. 1) Centro Regional de Estudios Genómicos, UNLP- Florencio Varela, 867C Buenos Aires, Argentina; 2) Departamento de Ciencias Básicas y Identification of a cup-dependent mRNA localization pathway for the Experimentales, UNNOBA, Pergamino, Buenos Aires, Argentina. early oocyte. Risa Broyer, Elena Monfort-Prieto, James Wilhelm. Section on Cell and Developmental Biology, UC San Diego, La Jolla, 857B CA. Using confirmed dicistronic gene structures from multiple Drosophilid species as a model for understanding eukaryotic translation diseases. 868A Henry C. Hunter, Christopher D. Smith. Biology Dept, San Francisco Germ plasm components exhibited directed transport during late State University, San Francisco, CA. oogenesis. Jack J. Lee, Kristina S. Sinsimer, Elizabeth R. Gavis. Department of Molecular Biology, Princeton University, Princeton, NJ. 858C The piNG-body - a novel non-membrane organelle in the nuage of 869B Drosophila male germ cells. Mikhail V. Kibanov, Ksenia S. Egorova, The effect of RNAi protein Armitage on oskar mRNA transport and Sergei S. Ryazansky, Olesia A. Sokolova, Alexei A. Kotov, Oxana M. localization in Drosophila oocyte. Linda Molla, Joseph, T. Olenkina, Anastasia D. Stolyarenko, Vladimir A. Gvozdev, Ludmila Cammarata, Irina, E. Catrina, Diana, P. Bratu. Department of V. Olenina. Laboratory of Biochemical Genetics of Animals, Biological Sciences, Hunter College CUNY, New York, NY. Department of Molecular Genetics of Cell, Institute of Molecular Genetics, RAS, Kurchatov sq., 2, 123182, Moscow, Russia. 870C Trailer hitch is a localization factor for a novel class of RNPs that 859A contain the translational repressor Hubcap. Elena Monfort-Prieto, Risa Drosophila RNase ZL is an essential gene involved in tRNA processing. Broyer, James Wilhelm. Section on Cell and Developmental Biology, Xie Xie, Veronica Dubrovskaya, Edward Dubrovsky. Biological UC San Diego, La Jolla, CA. Sciences, Fordham University, Bronx, NY. 871A 860B RNA interference: Does R2D2 witness Dicing? Tracey A. Lincoln, Drosophila Tis11 and its effects on mRNA expression. Youn-Jeong Phillip D. Zamore. Biochemistry and Molecular Pharmacology, Choi1, Wi Lai1, Robert Fedic2, James Mason2, Perry Blackshear1. 1) University of Massachusetts Medical School, Worcester, MA. Laboratory of Signal Transduction, NIEHS, Research Triangle Park, NC; 2) Laboratory of Molecular Genetics, NIEHS, Research Triangle 872B Park, NC. Wide-spread regulatory effects of endogenously expressed siRNAs on the transcriptomes of Drosophila melanogaster. Jian Lu, Andrew Clark. 227 Biotechnology Building Molec Biol & Gen, Cornell Univ, Ithaca, NY. 14850, USA.

POSTER SESSIONS See page 16 for presentation schedule Poster board number is in bold above title. The first author is the presenter. Full abstracts can be found online at drosophila-conf.org

873C 884B RNA-Seq and RNAi analyses of alternative splicing in the complex CG2264 (pentagone), a novel BMP modulator controlling male germline Drosophila dumpy gene. Amber Carmon, Ross MacIntyre. Dept stem cell maintenance. Qi Zheng1, Yiwen Wang2, Eric Vargas2, Molec Biol & Genetics, Cornell Univ, Ithaca, NY. Stephen DiNardo2. 1) Department of Biology, School of Arts and Sciences, University of Pennsylvania; 2) Department of Cell and 874A Developmental Biology, School of Medicine, University of Structure/function analysis of PPS: Does PPS contribute to Sex-lethal Pennsylvania. splicing autoregulation by regulating transcription? Ashley Kendig, Helen Salz. Dept Genetics, Case Western Reserve University, 885C Cleveland, OH. A novel role for Fizzy/Cdc20 in promoting neural stem cell survival in Drosophila. Chaoyuan Kuang, Cheng-Yu Lee. Life Sciences Institute, 875B University of Michigan, Ann Arbor, MI. A novel role for dADAR in 5'-UTR intron splicing regulation of rnp-4f pre-mRNA during Drosophila embryogenesis. G. Girija Lakshmi, 886A John A. Cook, Gabriel P. Jones, Roshni Parikh, Jack C. Vaughn. Hippo signaling regulates Drosophila intestine stem cell proliferation Zoology, Miami University, Oxford, OH. through multiple pathways. Fangfang Ren1, Bing Wang1, Tao Yue1, Eun-Young Yun2,3, Y.Tony Ip2, Jin Jiang1. 1) University of Texas 876C Southwestern Medical Center , Dallas, TX; 2) University of The Control of Lipid Metabolism by Splicing in Drosophila. Alexis A. Massachusetts Medical School Worcester, MA 01605; 3) National Nagengast1,3, Nicole Chichearo2, Thomas Carr1, Timothy Rudolph1, Academy of Agricultural Science, Rural Development Administration, Justin DiAngelo4. 1) Dept Biochemistry, Widener Univ, Chester, PA; 2) Suwon 441-100, Korea. Dept Biology, Widener Univ, Chester, PA; 3) Dept Chemistry, Widener Univ, Chester, PA; 4) Dept Biology, Hofstra Univ, Hempstead, NY. 887B Loss of Heterochromatin Protein 1a causes chaos in the germline. 877A Michael W. Vitalini, Lori L. Wallrath. Biochemistry, University of The Half-Pint protein plays a direct role in the regulation of alternative Iowa, Iowa City, IA. splicing and acts as a repressor in combination with Transformer-2. Shanzhi Wang1, Shihuang Su1, Eric Wagner2, William Mattox1. 1) 888C GENETICS, UT MD ANDERSON CANCER CENTER, HOUSTON, Orthogonal functions of BAB1 and BAB2 proteins in determining germ TX; 2) BIOCHEMISTRY AND MOLECULAR BIOLOGY, UT stem cell niches in the ovary of D. melanogaster. Mathieu Bartoletti1, HEALTH SCIENCE CENTER HOUSTON, TX. Thomas Rubin3, Fabienne Chalvet1,2,3, Nicolas Dos Santos2,3, Emilie Poisot2,3, Delphine Cumenal4, Jacqueline Leroy3, Fredrerique Peronnet4, Laurent Théodore1,2,3. 1) Centre de Génétique Moléculaire Stem Cells - UPR 2167, GIF SUR YVETTE, France; 2) Université Paris-Sud 11, 91405 Orsay France; 3) LGBC, Université Versailles St-Quentin 78035 878B Versailles, France; 4) UMR7622 - Biologie du Développement CNRS - Programmed Cell Death 4 promotes the differentiation of female UPMC Bâtiment C - 7ème étage - case 24 9, quai Saint-Bernard 75005 - germline stem cells. Amy C. Cash, Justen Andrews. Department of Paris, France. Biology, Indiana University, Bloomington, IN. 889A 879C Genetic ablation of the somatic hub cells in the drosophila testis. Phylis SEX-LETHAL downregulates nanos in the female germline to promote Hetie. Cell Biology, Johns Hopkins Univ, Baltimore, MD. differentiation. Johnnie Chau, Helen K. Salz. Dept Gen, Case Western Reserve Univ, Cleveland, OH. 890B Insulin signals control the competence of the Drosophila female 880A germline stem cell niche to respond to Notch ligands. Hwei-Jan Hsu1,2, Stat primarily regulates adhesion to the niche in male germline stem Daniela Drummond-Barbosa2. 1) Inst. of Cellular and Organismic cells, and not the undifferentiated state. Judith L. Leatherman1, Steve Biology, Taipei, Taiwan, Taiwan; 2) Department of Biocheistry and DiNardo2. 1) School of Biological Sciences, University of Northern Molecular Biology, Johns Hopkins Bloomberg School of Public Health, Colorado, Greeley, CO; 2) Department of Cell and Developmental Batimore, MD, USA. Biology, University of Pennsylvania School of Medicine, Philadelphia, PA. 891C Apontic restricts the stem cell population in the testis by inhibiting the 881B JAK/STAT signaling pathway. Michelle A. Starz-Gaiano, Archana Environmental and Genetic Control of Germline Stem Cell Divisions. Murali. Biological Sciences, University of Maryland Baltimore County, Benjamin B. Parrott, Alicia Hudson, Regina Brady, Cordula Schulz. Baltimore, MD. Dept Cell Biol, Univ Georgia, Athens, GA. 892A 882C Molecular and genetic studies on the posterior signaling center of the Comeback, a putative AAA-ATPase, and regulator of germline stem Drosophila lymph gland: factors controlling specification and cells? Yue Qian, Ye Wang, Cordula Schulz. Cellular Biology, maintenance of the hematopoietic progenitor niche. Jessica Renee University of Georgia, Athens, GA. Stoller-Conrad, Tsuyoshi Tokusumi, Yumiko Tokusumi, Robert A. Schulz. Department of Biological Sciences, University of Notre Dame, 883A Notre Dame, IN 46556, USA. Asymmetric cytokinesis and midbody inheritance during Drosophila germline stem cell division. Viktoria Salzmann, Amita Tiyaboonchai, Yukiko M. Yamashita. Life Sciences Institute, University of Michigan, Ann Arbor, MI.

POSTER SESSIONS See page 16 for presentation schedule Poster board number is in bold above title. The first author is the presenter. Full abstracts can be found online at drosophila-conf.org

893B 902B A novel side-by-side fused egg chamber phenotype in pak mutant The role chinmo in cyst stem cell (CySC) self-renewal in the Drosophila ovarioles indicates a role for Pak in cyst encapsulation. Stephanie testis. Marc Amoyel, Maria Sol Flaherty, Erika Bach. Pharmacology, Vlachos1, Ryan Conder2, Todd Nystul3, Nicholas Harden1. 1) New York University School of Medicine, New York, NY. Department of Molecular Biology & Biochemistry, Simon Fraser University, 8888 University Drive, Burnaby, BC, V5A 1S6 Canada; 2) 903C Institute of Molecular Biotechnology of the Austrian Academy of Fragile X protein controls neural stem cell proliferation. Matthew A. Sciences (IMBA), Dr. Bohr Gasse 3, A-1030 Vienna, Austria; 3) Callan1, Clemens Cabernard2, Jennifer Heck1, Chris Q. Doe2, University of California, San Francisco, 513 Parnassus Ave, San Daniela C. Zarnescu1,3,4. 1) Molecular & Cellular Biology, University Francisco, CA 94143. of Arizona, Tucson, AZ; 2) Institute of Molecular Biology, Howard Hughes Medical Institute, University of Oregon, Eugene, OR; 3) 894C Department of Neuroscience, University of Arizona, Tucson, AZ; 4) Live imaging cell migration within the Drosophila gonad. Lindsey Graduate Program in Genetics, University of Arizona, Tucson, AZ. Wingert1, Stephen DiNardo2. 1) Cell and Molecular Biology, University of Pennsylvania, Philadelphia, PA; 2) Cell and 904A Developmental Biology, University of Pennsylvania, Philadelphia, PA. Redox regulation by Keap1 and Nrf2 controls intestinal stem cell proliferation in Drosophila. Christine E. Hochmuth1, Benoît Biteau1, 895A Dirk Bohmann2, Heinrich Jasper1. 1) Department of Biology, Characterization of Midgut Stem Cell- and Enteroblast-Specific Gal4 University of Rochester, River Campus Box 270211, Rochester, NY, Lines in Drosophila. Xiankun Zeng, Chhavi Chauhan, Steven Hou. 14627, USA; 2) Department of Biomedical Genetics, University of Mouse Cancer Gen Program, NCI Frederick, Frederick, MD. Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY, 14620. 896B High-threshold Notch signaling promotes commitment of stem cell 905B daughters in the adult midgut. Allison J. Bardin1, Carolina Perdigoto2, A role for Caprin during oogenesis. John C. Reich, Ophelia Papoulas. François Schweisguth2. 1) Department of Developmental Biology and Molec Cell & Dev Biol, Univ Texas, Austin, TX. Cancer, Institut Curie, Paris, France CNRS URA3215 Inserm U934; 2) Department of Developmental Biology, Institut Pasteur, Paris, France 906C CNRS URA2578. Examining the Role of Robo/Slit Signaling in the Drosophila Testis Stem Cell Niche. Rachel R. Stine, Erika L. Matunis. Johns Hopkins 897C Sch Med, Baltimore, MD. An in vivo RNAi screen for Wnt signaling factors required for stem cell homeostasis in the Drosophila intestine. Anna-Lisa Boettcher, Nadine 907A Wennemuth, Jun Zhou, Nicola Berns, Veit Riechmann, Michael Zfrp8 and Hematopoiesis. William Tan, Svetlana Minakhina, Ruth Boutros. German Cancer Research Center (DKFZ), Div. Singnaling and Steward. Waksman Institute, 190 Frelinghuysen Rd, Rutgers Functional Genomics and University of Heidelberg, Department of Cell University, Piscataway, NJ 08854. and Molecular Biology, Faculty of Medicine Mannheim, Heidelberg.

898A Techniques and Functional The role of the JAK/STAT pathway in ovarian follicle stem cell self- renewal. Natania Field1, Cynthia Vied2, Daniel Kalderon1. 1) Genomics Department of Biological Sciences, Columbia University, New York, NY; 2) Department of Biomedical Sciences, Florida State University, 908B Tallahassee, FL. Microarray and CAGE analysis of gene expression from larval RNA. Eric Bremer1, Mitchell Dushay2. 1) Precision Biomarker Resources, 899B Inc, Evanston, IL 60201; 2) Biology, Illinois Institute of Technology, Regulation of intestinal regeneration by Insulin/Notch signaling Chicago, IL 60616. interactions. Subir Kapuria, Jason Karpac, Heinrich Jasper. Biology Department, University of Rochester, Rochester, NY. 909C Erroneous attribution of relevant transcription factor binding sites 900C despite successful prediction of cis-regulatory modules. Elizabeth R. The Hippo pathway regulates intestinal stem cell proliferation during Brennan1,2, Marc S. Halfon1,2. 1) Department of Biochemistry, SUNY Drosophila adult midgut regeneration. Rachael L. Shaw1, Alexander at Buffalo, Buffalo, NY; 2) NYS Center of Excellence in Bioinformatics Kohlmaier2, Cédric Polesello1,3, Cornelia Veelken2, Bruce Edgar2,4, & Life Sciences. Nicolas Tapon1. 1) Apoptosis and Proliferation Control Laboratory, London Research Institute, London, United Kingdom; 2) ZMBH-DKFZ 910A Alliance, Im Neuenheimer Feld 282, D-69120 Heidelberg, Germany; 3) Tools for Enhancer Discovery and Analysis. Thomas Brody1, Amar Centre de Biologie du Développement, UMR5547, CNRS/Université Yavatkar2, Mukta Kundu1, Jermaine Ross1, Alexander Kuzin1, Paul Sabatier Toulouse III, 118 route de Narbonne, 31062 Toulouse, Ward F. Odenwald1. 1) Neural Cell-Fate Determinants, NINDS/NIH, France; 4) Division of Basic Sciences, Fred Hutchinson Cancer Bethesda, MD; 2) Division of Intramural Research Information Research Center, 1100 Fairview Ave. N., Seattle, WA 98109, USA. Technology Program.

901A 911B Identification of Gastric Stem Cells in Adult Drosophila. Shree R. Cross-Species Expression Profiling Identifies Functional Genes in Singh, Xiankun Zeng, Zhiyu Zheng, Steven Hou. Mouse Cancer Gen Drosophila Eye Development. Bryce Daines1, Yumei Li1, Hui Wang2, Prog, NCI/NIH, Frederick, MD. Xiaobo Zhou3, Graeme Mardon1, Rui Chen1,2. 1) Molec & Human Gen, Baylor College Med, Houston, TX; 2) Human Genome Sequencing Center, Baylor College Med, Houston, TX; 3) Bioengineering and Bioinformatics Program, The Methodist Hospital Research Institute, Houston, TX.

POSTER SESSIONS See page 16 for presentation schedule Poster board number is in bold above title. The first author is the presenter. Full abstracts can be found online at drosophila-conf.org

912C 922A SigWiki: A collaborative genomic resource for machine-readable The use of next-generation sequencing to functionally dissect the descriptions of regulatory DNA signatures. Albert J. Erives1, Victoria functions of the Drosophila larval midgut. Philip Batterham, Stephen Boggiano1, Alexandra Arnold1, Curtis J. Hansen1, Alexander R. Pearce, Phillip Daborn. Genetics Dept, Melbourne University, Lloyd1, Grace A. Nauman1, Kerrie K. Nguyen1, Katie Ann Paden1, Parkville, Victoria, Australia. Dov A. Pechenick2, Shirine Sajjadi1, Arvis Sulovari1, Anna L. Tyler2. 1) Dept Biological Sci, Dartmouth Col, Hanover, NH; 2) Dept Genetics, 923B Dartmouth Medical School, Hanover, NH. Morphogen gradients quantified by sub-single embryo RNA-seq. Peter A. Combs1, Susan E. Lott2, Michael B. Eisen2,3. 1) Biophysics Grad 913A Group, Univ California, Berkeley, CA; 2) Department of Molecular and Gene annotation of 90 kb genomic DNA sequence of Drosophila Cell Biology, Univ California, Berkeley, CA; 3) Howard Hughes mojavensis dot chromosome. Amber L. Harlan, Joshua F. Machone, Medical Institute, Univ California, Berkeley, CA. James E. J. Bedard. Department of Biology and Earth Sciences, Adams State College, Alamosa, CO. 924C Detecting Novel Transposable Element Insertions with High- 914B Throughput Paired-End Sequencing. Julie M. Cridland, Kevin Robust estimates for the range of morphogen gradients. Jitendra Thornton. Ecology and Evolutionary Biology, University of California Kanodia1, Yoosik Kim1, Kwanghun Chung2, Hang Lu2, Stanislav - Irvine, Irvine, CA. Shvartsman1. 1) Chemical & Biological Engineering, Princeton University, Princeton, NJ; 2) School of Chemical & Biomolecular 925A Engineering and Parker H. Petit Institute for Bioengineering & Next generation sequencing to identify novel X-linked EMS induced Bioscience, Georgia Institute of Technology, Atlanta, GA. mutations. Ana Clara Fernandes1,2, Gert-Jan Hulselmans1, Jan Slabbaert1,2, Sabine Keunen1,2, Valerie Uytterhoeven1,2, Jaroslaw 915C Kasprowicz1,2, Stein Aerts1, Patrik Verstreken1,2. 1) K.U.Leuven, FlyExpress: A Platform for Discovering Co-expressed Genes via Center for Human Genetics; 2) VIB, Department of Molecular and Comparative Image Analysis of Spatial Patterns in Drosophila Developmental Genetics. Embryogenesis. Sudhir Kumar1,2, Michael McCutchan2, FlyExpress Consortium2. 1) School of Life Sciences, Arizona State Univ, Tempe, 926B AZ; 2) Center for Evolutionary Medicine and Bioinformatics, Arizona Evaluating performance for RNA-seq with external RNA controls. State Univ, Tempe, AZ. Lichun Jiang1, Carlo Artieri1, Yu Zhang1, Nicolas Mattiuzzo1, David Sturgill1, Renhua Li1, John Malone1, Marc Salit2, Brian Oliver1. 1) 916A Developmental Genomics Section, LCDB, NIDDK, National Institutes Introduction of a genomic tag in roX1 through gene conversion. Manasi of Health, Bethesda, MD 20892; 2) Biochemical Science Division, Apte1, Victoria Moran1, Richard Kelley2, Victoria Meller1. 1) Dept. National Institute of Standards and Technology, 100 Bureau Drive, Mail of Biological Sciences, Wayne State University, Detroit, MI; 2) Dept. of Stop 8313, Gaithersburg, MD 20899, USA. Molecular and Human Genetics, Baylor college of Medicine, Houston, TX. 927C RNASeq Reveals Novel Regulatory Network Genes in Drosophila Eye 917B Development. Landry E. Nfonsam1, Joann Mudge2, Faye Schilkey2, Donor design limits using Zinc Finger Nucleases. Kelly J. Beumer, Jon Ryan Kim2, Jennifer Curtiss1. 1) Biology, New Mexico State Trautman, Dana Carroll. Dept Biochem, Univ Utah, Salt Lake City, University, Las Cruces, NM; 2) National Center for Genome Resources UT. (NCGR), Santa Fe, NM.

918C 928A A novel method to generate gene deletions by induction of DSB in the Genome sequencing for the Drosophila ModEncode project: Progress on transgene. Maria V. Kim, Artem Tkachuk, Anna Aristarkhova, the Genome Sequencing of D. biarmipes, D. bipectinata, D. elegans, D. Mikhail Savitsky. Institute of Gene Biology, RAS, Moscow, Russian eugracilis, D. ficusphila, D. kikkawai, D. rhopaloa, D. takahashii, and Federation. the Oregon R strain of D.melanogaster. Steven Scherer1, Stephen Richards1, Shalini Jhangiani1, Yuan-Qing Wu1, Kim Worley1, 919A Artyom Kopp2, Michael Eisen3, Peter Cherbas4, Richard Gibbs1. 1) Defining off-target cleavage in a pair of zinc finger nucleases. Human Genome Sequencing Center, Baylor College of Medicine, Kusumika Mukherjee, Dana Carroll. Biochemistry, University of Houston, TX; 2) Department of Evolution and Ecology, University of Utah, Salt Lake City, UT. California at Davis, Davis, CA; 3) Howard Hughes Medical Institute and Department of Cell and Molecular Biology, University of California at 920B Berkeley, Berkeley, CA; 4) Department of Biology and Center for Brain transcriptional regulatory network predicts behaviorally-related Genomics and Bioinformatics, Indiana University, Bloomington IN. functions for conserved transcription factors. Seth A. Ament1,2,3, Sriram Chandrasekaran1, James A. Eddy1, Sandra Rodriguez-Zas1, 929B Bruce R. Schatz1, Nathan D. Price1, Kristin Scott2,3, Gene E. PoPoolation: a toolbox for population genetic analysis of 2nd generation Robinson1. 1) Institute for Genomic Biology, University of Illinois, sequencing data from pooled individuals. Christian W. Schloetterer1, Urbana, IL; 2) Howard Hughes Medical Institute; 3) Department of Robert Kofler1, Pablo Orozco-ter Wengel1, Nicola De Maio1, Ram Molecular and Cellular Biology, University of California, Berkeley, CA. Vinay Pandey1, Viola Nolte1, Andreas Futschik2, Carolin Kosiol1. 1) Inst f Populationsgenetik, Vetmeduni Vienna, Wien, Austria; 2) 921C Department of Statistics, University of Vienna, Vienna, Austria. Creating open source microscope automation for high-throughput imaging of the BDGP insitu hybridizations. Erwin Frise, Bill Fisher, Ann Hammonds, Richard Weiszmann, Susan Celniker. BDGP/Genome Dynamics, Lawrence Berkeley National Labs, Berkeley, CA.

POSTER SESSIONS See page 16 for presentation schedule Poster board number is in bold above title. The first author is the presenter. Full abstracts can be found online at drosophila-conf.org

930C 938B Tracking and Automated Behavior Recognition of Drosophila with a The isPIN Project. James D. Baker1, John Bixby2, Willie Buchser2, Multi-Resolution Camera System. Reza Ardekani1, Anurag Biyani1, Maria Blulina1, Xiaodong Cai3, Sophie Deng1, Vineet Gupta4, Neil Ravi Prakash1, Sergey Nuzhdin1, Simon Tavaré1,2. 1) Department of Johnson5, Tatsuo Kagesawa1, Daichi Kamiyama1, Michael Kim6, Biological Sciences, University of Southern California, Los Angeles, Vance Lemmon2, Tiffany Li1, Mitsunori Ogihara7, Hasitha CA; 2) Department of Applied Mathematics and Theoretical Physics, Samarajeewa1, Nima Sharifai1, Robin Smith2, Gavril Tsechpenakis8, University of Cambridge, Cambridge CB3 0WA, UK. Grace Zhai6, Akira Chiba1. 1) Dept Biol, Cox Sci Ctr, Univ Miami, Coral Gables, FL; 2) The Miami Project to Cure Paralysis University of 931A Miami, School of Medicine Miami, Fl; 3) University of Miami, College The Bloomington Deletion and Duplication Projects. Kevin Cook, of Engineering, Coral Gables, FL; 4) Miami Institute of Renal Medicine, Russell Garton, C. Adam Brown, Thomas Kaufman, Kimberley School of Medicine, University of Miami, Miami, FL; 5) Physics Cook. Dept Biol, Indiana Univ, Bloomington, IN. Department, University of Miami, Coral Gables, Fl; 6) Molecular and Cellular Pharmacology Miller School of Medicine Rosenstiel Medical 932B Sciences Building, Miami, FL; 7) Department of Computer Science, Expanding the Utilities Of G-MARET In Drosophila; Taking It A Step University of Miami,Coral Gables, FL; 8) Computer & Information Ahead. Indrani Gupta, Ryohei Yagi, Konrad Basler. Institute of Science Dept., Indiana University-Purdue University Indianapolis Molecular Life Sciences, University of Zurich, Zurich, Switzerland. Indianapolis, IN.

933C 939C High-throughput analysis of morphogen gradients using a microfludic Transgene Design of isPIN. Maria Bulina1, James Baker1, Kenneth device. Yoosik Kim1, Kwanghun Chung2, Jitendra S. Kanodia1, Wan2, Charles Yu2, Susan Celniker2, Akira Chiba1. 1) Biology, Emily Gong2, Stanislav Y. Shvartsman1, Hang Lu2. 1) School of University of Miami, Coral Gables, FL; 2) Lawrence Berkeley National Chemical and Biological Engineering and Lewis-Sigler Institute for Laboratory, Berkeley, CA 94720. Integrative Genomics, Princeton University, Princeton, NJ 08544 USA; 2) School of Chemical and Biomolecular Engineering and Parker H. 940A Petit Institute for Bioengineering and Bioscience, Georgia Institute of Informatics of isPIN. Sophie T. Deng1, Vance Lemmon2, Willie Technology, Atlanta, GA 30332, USA. Buchser2, Robin Smith2, Mitsunori Ogihara3, Hasitha Samarajeewa1, Akira Chiba1. 1) Biology, University of Miami, Coral 934A Gables, FL; 2) Neurosurgery, University of Miami, Miami, FL; 3) Production and Purification of Nora Virus ORF 3 Protein. Andrew Computer Science, University of Miami, Coral Gables, FL. Prososki, Darby Carlson, Ethan Cordes, Brad Ericson, Kimberly Carlson. Biology Department, University of Nebraska at Kearney, 941B Kearney, NE. In vivo Imaging of isPIN. Tatsuo Kagesawa1, Maria Bulina1, Sophie Deng1, Michael Kim2, James Baker1, Akira Chiba1. 1) Biology, 935B University of Miami, Coral Gables, FL; 2) Pharmacology, University of A genetic mosaic screen for enhancer-trap FLP-induced intersectional Miami, Miami, FL. GAL80/GAL4 expression in Drosophila imaginal discs. Brittany N. Smith1, Rudolph A. Bohm1,2, William P. Welch1, Lindsey K. 942C Goodnight1, Bing Zhang1, John P. Masly1. 1) University of Oklahoma, isPIN: in vivo Imaging. Tatsuo Kagesawa, Maria Bulina, Sophie Department of Zoology, Norman, OK; 2) Brandeis University, Deng, Michael Kim, James Baker, Akira Chiba. University of Miami, Department of Biology, Waltham, MA. Coral Gables, FL., USA.

936C 943A Monitoring DNA Accessibility and Epigenetic Status in Live Animals Quantification of isPIN. Daichi Kamiyama1, Chittanon Buranachai2, with Fluorescent Reporters. Can Zhang1, Michael Novo1, Nianwei Robert Clegg2, Akira Chiba1. 1) Biology, University of Miami, Coral Lin1, Yiyong Tan2, Huabei Jiang2, Lei Zhou1. 1) Molecular Genetics Gables, FL; 2) Physics, University of Illinois, Urbana, IL. and Microbiology Dept, University of Florida, Gainesville, FL; 2) Biomedical Engineering Dept, University of Florida, Gainesville, FL. 944B A Sample Analysis of isPIN. Nima Sharifai, Maria Bulina, Daichi 937A Kamiyama, Akira Chiba. Biology, University of Miami, Coral Gables, pTubHA4C: a new vector for constitutive expression in Drosophila. Yan FL. Zhang1, Stephanie Arcia1,2, Pedro Fernandez-Funez1,3, Diego Rincon-Limas1. 1) Neurology, University of Florida, Gainesville, FL; 945C 2) Science for Life Undergraduate Program; 3) Neuroscience, University Model Neurons of isPIN. Gavriil Tsechpenakis1, Hasitha of Florida, Gainesville, FL. Samarajeewa2, Miahcel Kim3, Akira Chiba2. 1) Computer Science, ndiana University-Purdue University, Indianapolis, IN; 2) Biology, University of Miami, Coral Gables, FL; 3) Pharmacology, University of Miami, Miami, FL.

946A The BDGP Universal Proteomics Resources. Kenneth H. Wan1, Charles Yu1, James Baker3, Maria Boulina3, Ben Booth1, Joe Carlson1, Akira Chiba3, Ann Hammonds1, Guruharsha Kuthethur2, Julian Mintseris2, Robert Obar2, Soo Park1, Jean-François Rual2, Richard Weiszmann1, Bo Zhai2, Susan Celniker1. 1) Dept Genome Biol, Lawrence Berkeley Natl Lab, Berkeley, CA; 2) Dept of Cell Biology, Harvard Medical School, Boston, MA;; 3) Univ. of Miami, Coral Gables, FL.

POSTER SESSIONS See page 16 for presentation schedule Poster board number is in bold above title. The first author is the presenter. Full abstracts can be found online at drosophila-conf.org

947B A New Technique for Incorporating Small Mutations In Large Genes: Educational Initiatives Mutagenesis via Serial Small Mismatch Recombineering (MSSMR). Julie Jacobs, Xiaojing Hong, Daniel Eberl. Department of Biology, 953B University of Iowa, Iowa City, IA 52242, USA. Identifying gene mutations in Drosophila melanogaster with inverse PCR: A thematic academic laboratory experience. Dawn M. Hemmerle, 948C Gerald B. Call. Department of Pharmacology, Arizona College of Manipulating Gene Expression Using Recombineering. Hitesh Osteopathic Medicine, Midwestern University, Glendale, AZ. Kathuria, Parul Khurana. School of Natural Science and Mathematics, Indiana University East, Richmond, IN-47374. 954C [email protected]. FIRST: Fellowships in Research and Science Teaching - A Postdoctoral Training Opportunity Blending Bench Research and Undergraduate 949A Teaching at Minority Serving Institutes. Jacob Daniel Kagey1, Seth M. A novel method for mosaic gene expression with Cre/loxP system in Kelly1, Arri Eisen2, J. K. Haynes3, Douglas C. Eaton4. 1) Department Drosophila embryos. Naotaka Nakazawa1, Kiichiro Taniguchi1, of Cell Biology, Emory University, Atlanta, GA; 2) Department of Takashi Okumura1, Reo Maeda1, Kenji Matsuno1,2. 1) Department of Biology, Emory University, Atlanta, GA; 3) Department of Biology, Biological Science and Technology; Tokyo University of Science; Noda, Morehouse College, Atlanta, GA; 4) Department of Physiology, Emory Chiba, Japan; 2) Research institute for science and technology; Tokyo University, Atlanta, GA. University of Science; Noda, Chiba, Japan. 955A 950B Complementary pairing: An integrative semester-long Genetics lab Mapping of signaling networks through synthetic genetic interaction project that reinforces lecture material. Jennifer A. Kennell. Biology, analysis by RNAi. Thomas Horn1, Thomas Sandmann1, Bernd Vassar College, Poughkeepsie, NY. Fischer2, Wolfgang Huber2, Michael Boutros2. 1) Signaling & Functional Gen, German Cancer Res Ctr, Heidelberg, Germany; 2) 956B Genome Biology Unit, EMBL, Heidelberg, Germany. Putting Mendel to Work; The Matrix. Eric C. Liebl. Dept Biol, Denison Univ, Granville, OH. 951C The TRiP: The Transgenic RNAi Project at Harvard Medical School. 957C Donghui Yang-Zhou1, Laura Holderbaum1, Jianquan Ni1, Luping Exploring genome organization and chromatin structure in Drosophila, a Liu1, Norbert Perrimon1,2, Lizabeth Perkins1,3. 1) Harvard Medical distributed undergraduate research project. Christopher Shaffer1, School, Dept. of Genetics, Boston, MA 02115; 2) Howard Hughes Wilson Leung1, James Bedard2, Satish Bhalla3, Martin Burg4, Vidya Medical Institute; 3) Pediatric Surgical Research Labs, Mass. General Chandrasekaran5, Catherine Coyle-Thompson6, Justin DiAngelo7, Hospital, Boston, MA 02114. Christopher Jones8, Lisa Kadlec9, Gerard McNeil10, Alexis Nagengast11, Don Paetkau12, Ken Saville13, Joyce Stamm14, Matthew 952A Wawersik15, Leming Zhou16, Sarah C. R. Elgin1. 1) Washington U, St A genome-scale shRNA resource for transgenic RNAi in Drosophila. Louis, MO; 2) Adams State, Alamosa CO; 3) Johnson C Smith U, Rui Zhou1,6, Jian-Quan Ni1,5,6, Benjamin Czech2,6, Lu-Ping Liu1,5, Charlotte, NC; 4) Grand Valley State U, Allendale, MI; 5) Saint Mary’s Laura Holderbaum1, Donghui Yang-Zhou1, Hye-Seok Shim1, of CA, Moraga, CA; 6) Cal State- Northridge, Northridge, CA; 7) Dominik Handler3, Philip Karpowicz1, Richard Binari1, Matthew Hofstra, Hempstead, N.Y; 8) Moravian, Bethlehem, PA; 9) Wilkes U, Booker1, Julius Brennecke3, Lizabeth A. Perkins4, Gregory Wilkes-Barre, PA; 10) York College-CUNY, NY; 11) Widner, Chester, Hannon2, Norbert Perrimon1. 1) Department of Genetics, Harvard PA; 12) Saint Mary's, Notre Dame, IN; 13) Albion, Albion, MI; 14) U of Medical School, HHMI, Boston, MA; 2) Cold Spring Harbor Evansville, Evansville, IN; 15) William & Mary, Williamsburg, VA; 16) Laboratory, HHMI, Cold Spring Harbor, NY; 3) IMBA-Institute of Univ of Pittsburgh, Pittsburgh, PA. Molecular Biotechnology, Vienna, Austria; 4) Pediatric Surgical Research Labs, MGH, Harvard Medical School, Boston, MA; 5) Gene 958A Regulation Laboratory & Tsinghua Fly Center, Tsinghua University, Mapping and cloning 100-year-old mutations in an undergraduate Beijing, China; 6) Equal contribution. course. Eric P. Spana, Daniel C. Chun, Yi Dong, David Jung, Jason Klein, Si Won Oak, Zachary B. Powell, David B. Rothchild, Brandon Ruderman, Arun Sharma, Alvin H. Shi, Bo Sun, Andrea Stewart. Biology Dept, Duke Univ, Durham, NC.

Speaker and Author Index

This index includes names of speakers for the Opening General Session and for Plenary Sessions I and II, and names of all authors of programmed abstracts. The number following an author’s name refers to the abstract program number. A, B, or C following a number indicates a poster presentation. The presenting author of an abstract is noted with an asterisk. Please note that the complete abstract is available at drosophila-conf.org.

A Aoyama, Naoki, ...... 156, 223A* Apte, Manasi, ...... 916A* Aquadro, Charles, ...... 28 Abdelwahid, Eltyeb, ...... 65* Aquadro, Charles F., ...... 35 Abdou, Mohamed A., ...... 780C* Arama, Eli, ...... 274A*, 289A, 291C Abdullayev, Alex E., ...... 382A Aranjuez, George, ...... 218B Abhishek, Ankur, ...... 374B Araujo, Sofia J., ...... 216C* Ablack, Amber, ...... 553A Arbeitman, Michelle, ...... Plenary Session I, 831C Abmayr, Susan, ...... 83 Arbeitman, Michelle N., ...... 32 Abmayr, Susan M., ...... 115, 376A Arcia, Stephanie, ...... 937A Abreu-Blanco, Maria Teresa, ...... 187A Arcineiga, Estela, ...... 54 Abruzzi, Katharine, ...... 71 Ardekani, Reza, ...... 930C* Adler, Paul, ...... 167B Argue, Kathryn J., ...... 657C*, 665B* Adolphsen, Katie, ...... 460A, 605B Aristarkhova, Anna, ...... 918C Adriana, Muñoz-Hernández, ...... 447C* Armstrong, J. Douglas, ...... 135 Aebersold, Ruedi, ...... 242B Armstrong, Jennifer A., ...... 349A* Aerts, Stein, ...... 829A, 925A Armstrong, Morag, ...... 150 Affolter, Markus, ...... 59, 544A Arnold, Alexandra, ...... 912C Aggarwal, Dau Dayal, ...... 525C* Arnosti, David N., ...... 842B* Agnès, François, ...... 293B Arora, Gurpreet K., ...... 201C* Ahmad, Kami, ...... Plenary Session II, 80 Artavanis-Tsakonas, Spyros, ...... 136*, 228C Ahmad, Shaad M., ...... 100*, 835A Arthaud, Laury,...... 770B Ahmed, Wylie, ...... 728B Artieri, Carlo, ...... 926B Ahn, Hye-Mi, ...... 626B Artieri, Carlo G., ...... 480C* Ainsley, Joshua A., ...... 673A Arunachalam, Manonmani, ...... 815B* Ait-Ahmed, Ounissa, ...... 568A* Arya, Richa, ...... 296B, 717C* Ajjuri, Rami, ...... 425B Ashburner, Michael, ...... 135 Akasaka, Takeshi, ...... 402C* Ashton-Beaucage, Dariel, ...... 232A* Alain, Vincent, ...... 558C Aso, Yoshinori, ...... 69 Alain Labbé, Alain, ...... 199A Assaker, Gloria, ...... 220A Alam, Mohammad Atif, ...... 400A Asztalos, Zoltan, ...... 41 Alanis, Raul, ...... 645C Atallah, Joel, ...... 735C*, 746B Alayari, Nikki, ...... 12 Atkinson, Nigel, ...... 374B, 399C, 680B Aldrich, John, ...... 347B* Audibert, Agnès, ...... 270C Alekseyenko, Artyom A., ...... 348C*, 366C, 381C Austin, Christina, ...... 760A Alenius, Mattias, ...... 118* Austin, Christina L., ...... 244A* Alexander, Brandy, ...... 637A Ausubel, Frederick, ...... 620B Algazeery, Ahmed, ...... 568A Avidor-Reiss, Tomer, ...... 308B* AlHaj Abed, Jumana, ...... 389B* Avila, Frank W., ...... 582C* Alkhori, Liza, ...... 118 Axelrod, Jeff, ...... 170B Allan, Douglas, ...... 664A, 707B*, 708C Axelrod, Jeffrey D., ...... 51 Allan, Douglas W., ...... 671B Ayroles, Julien, ...... 25 Allen, Jessica, ...... 157A* Ayukawa, Tomonori, ...... 156, 223A Alvarez, Diana, ...... 500B* Azad, Priti, ...... 448A* Amador, Ariadna, ...... 775A* Azzaz, Abd Elhamid, ...... 343A Amell, Amanda,...... 605B Ament, Seth A., ...... 920B* Amin, Victor, ...... 487A B Amiri, Nona, ...... 788B Amoyel, Marc, ...... 902B* Babcock, Daniel T., ...... 682A Amrein, Hubert, ...... 687C, 690C Babenko, Vladimir N.,...... Plenary Session I (continued) Anderl, Ines, ...... 119, 609C* Bach, Erika, ...... 902B Anderson, Michael A., ...... 93 Bachtrog, Doris, ...... 488B, 490A, 496A, 499A, 514A, 541A Anderson, Ray, ...... 750C Badgett, Matthew, ...... 142 Anderssen, Endre, ...... 110 Badugu, RamaKrishna, ...... 346A Andó, István, ...... 611B Baer, Magdalena M., ...... 544A* Ando, Tadashi, ...... 168C Bafna, Vineet, ...... 507C Andreas, Bergmann, ...... 277A Bai, Hua, .. 766A* Andrew, Deborah, ...... 545B, 546C, 552C, 812B Bailey, Christopher, ...... 248B Andrews, Justen, ...... 839B, 878B Bailin, Samuel S., ...... 29 Andrianov, Boris V., ...... 523A Bain, Clint L., ...... 535A, 536B Anholt, Robert R. H., ...... 678C Bajpayi, Anjali, ...... 400A Antonio, Baonza, ...... 269B Bakatselou, Christina, ...... 610A Antonio, Christian W., ...... 277A* 84

Speaker and Author Index

Baker, Bruce, ...... 70 Belitsky, Gennadiy A., ...... 340A Baker, David, ...... 21 Bellaïche, Yohanns, ...... 332B Baker, James, ...... 939C, 941B, 942C, 946A Bellamkonda, Kishan, ...... 104 Baker, James D., ...... 938B* Bellen, Hugo, ...... 23, 140, 224B, 226A, 227B, 420C, 445A, 446B Baker, Nicholas, ...... 238A, 307A Bellen, Hugo J., ...... 67 Baker, Nicholas E., ...... 287B Belote, John, ...... 598A Baker, Ruth E., ...... 331A* Belyaeva, Elena S., ...... Plenary Session I (continued) Bakker, Hans, ...... 230B Ben El Kadhi, Khaled, ...... 312C* Bala, Fejzije, ...... 700A Benes, Judith, ...... 389B Balasov, Maxim, ...... 266B Benhra, Najate, ...... 206B Balasundaram, Sujatha, ...... 65 Bennett, Joan W., ...... 428B Balmer, Sophie M., ...... 158B* Beno, Milan, ...... 252C Baloh, Robert W., ...... 669C Ben-Shahar, Yehuda, ...... 686B Bantignies, Frédéric, ...... 390C* Berg, Celeste, ...... 577A, 581B Bao, Hong, ...... 137, 696C, 727A Berger, M., ...... 109 Barbash, Daniel, ...... 30 Berger, Susanne, ...... 173B Barbash, Daniel A., ...... 10, 35 Bergland, Alan O., ...... 526A* Barbee, Scott A., ...... 16 Bergman, Casey M., ...... 821B Barber, Diane, ...... 45 Bergmann, Andreas, ...... 198C*, 285C, 290B Barbosa, Vitor, ...... 262A Bergmann, Sven, ...... 59 Barbosa, Vitor J., ...... 97* Bergstralh, Dan, ...... 169A Barckmann, Bridlin, ...... 602B Berhane, Hebist, ...... 163A Bardin, Allison, ...... Opening General Session Bernard, Fred, ...... 823A Bardin, Allison J., ...... 896B* Bernards, Andre, ...... 110 Baril, Caroline, ...... 232A Berndt, Anthony, ...... 708C* Barolo, Scott E., ...... 481A* Berns, Nicola, ...... 897C Barrios, Natalia, ...... 554B* Bernstein, Sanford I., ...... 50, 172A*, 461B Barry, William E., ...... 767B* Berry, Cameron, ...... 338B* Barshow, Suzanne, ...... 18 Besse, Philippe, ...... 829A Barth, Julia M. I., ...... 273C* Betrán, Esther, ...... 485B, 503B Bartlett, Bryan, ...... 776B, 782B Beumer, Kelly J., ...... 917B* Bartoletti, Mathieu, ...... 888C* Bezdan, Daniela, ...... 297C Basciotta, Matthew, ...... 804C* Bhalla, Satish, ...... 957C Bashaw, Greg, ...... 692B Bhat, Amar, ...... 399C Bashir, Ali, ...... 507C Bhatt, Parag, ...... 714C Bashirullah, Arash, ...... 111, 280A, 282C, 699C Bi, Xiaolin, ...... 286A* Basler, Konrad, ...... 932B Bialobrodski, Adam, ...... 461B Bassett, Andrew Roger, ...... 854B* Bianco, Ambra, ...... 192C* Bassham, Susan, ...... 495C Bickel, Sharon E., ...... 318C Bassuk, Alex, ...... 51 Biehs, Brian, ...... 58 Bateman, Jack R., ...... 79* Bier, Ethan, ...... 622A, 710B, 759C, 819C Bates, Emily, ...... 758B Biggin, Mark, ...... 838A Bates, Emily A., ...... 758B* Biggin, Mark D.,...... 840C Batterham, Philip, ...... 922A* Bilak, Amber E., ...... 278B* Baum, Buzz, ...... 185B, 323B Bild, Nicholas A., ...... 765C Bauman, Kenneth, ...... 408C Bilder, David, ...... 95 Baumgardt, Magnus, ...... 695B*, 723C Bilen, Julide, ...... 646A* Baumgartner, Roland, ...... 144, 325A* Biliske, Jennifer A., ...... 125 Baxley, Ryan M., ...... 78, 377B* Binari, Richard, ...... 952A Bayarmagnai, Battuya, ...... 339C Birchler, James, ...... 388A, 543C, 841A Bayat, Vafa, ...... 224B, 420C*, 445A, 446B Birman, S., ...... 666C Bayer, Cynthia, ...... 556A Birnbaum, Morris, ...... 768C, 772A Baylies, Mary, ...... 563B Birse, Ryan T., ...... 412A* Baylies, Mary K., ...... 557B, 564C Biteau, Benoît, ...... 904A Beatty, Catherine, ...... 641B Bitner-Mathe, Blanche, ...... 466A* Beatty, Joshua, ...... 837C Bitner-Mathé, Blanche C., ...... 652A Beckerle, Mary C., ...... 177C Bivik, Caroline, ...... 695B, 723C Beckett, Karen, ...... 563B Bixby, John, ...... 938B Beckingham, Kathleen M., ...... 645C* Biyani, Anurag, ...... 930C Beckwith, Kristopher, ...... 781A* Björklund, Gunnel, ...... 636C Becnel, Jaime, ...... 72 Bjorum, Sonia, ...... 645C Bedard, James, ...... 957C Blackshear, Perry,...... 860B Bedard, James E. J., ...... 913A Blair, Seth, ...... 239B Beekman, Chapman, ...... 136 Bland, Michelle, ...... 772A Beeler, J. Scott, ...... 316A Bland, Michelle L., ...... 768C* Begun, David J., ...... 491B Bloch Qazi, Margaret C., ...... 582C Behmer, Spencer T., ...... 777C, 779B Blulina, Maria, ...... 938B Behnke, Jason, ...... 631A Blumenstiel, Justin P., ...... 382A* Beitel, Greg, ...... 547A Blumenthal, Edward M., ...... 578B, 585C Beitel, Greg J., ...... 40*, 89 Bodeen, William J., ...... 404B* Bejsovec, Amy, ...... 253A Bodmer, Rolf, ...... 12, 50, 131, 402C, 403A, 412A, 566B, 790A 85

Speaker and Author Index

Boekel, Christian, ...... 148* Brummel, Theodore, ...... 794B Boettcher, Anna-Lisa, ...... 897C* Bryant, Bart, ...... 852C Boettiger, Alistair, ...... 830B Bucciarelli, Elisabetta, ...... 350B Boettiger, Alistair N., ...... 138* Buceta, Javier,...... 6 Boggiano, Julian, ...... 7 Buchanan, Sean M., ...... 670A* Boggiano, Victoria, ...... 912C Buchon, Nicolas, ...... 120*, 617B Bohm, Rudolf, ...... 137 Buchser, Willie, ...... 938B, 940A Bohm, Rudolph A., ...... 935B Budnik, Vivian, ...... Plenary Session II, 19 Bohmann, Dirk, ...... 904A Bugga, Lakshmi V., ...... 349A Boissoneau, Elisabeth, ...... 293B Bulina, Maria, ...... 939C*, 941B, 942C, 944B Bokov, Alex, ...... 74 Bulyk, M. L., ...... 109 Bolkan, Bonnie J., ...... 268A, 421A* Buranachai, Chittanon, ...... 943A Bonaccorsi, Silvia, ...... 350B* Burch, Brandon, ...... 272B Bonanno, Liana,...... 760A Burg, Martin, ...... 667A, 957C Bonn, Bettina, ...... 182B Burgess, Jason, ...... 250A* Bonneaud, Nathalie, ...... 237C Burgio, Giosalba, ...... 352A Bonnet, Isabelle, ...... 332B Burke, Molly K., ...... 510C* Booker, Matthew, ...... 133, 952A Burla, Romina, ...... 351C Booth, Ben, ...... 946A Burn, Katherine M., ...... 569B* Borensztejn, Antoine, ...... 293B* Busser, Brian W., ...... 835A Borodulin, Igor, ...... 737B Busser, B. W., ...... 109* Bosch, Justin A., ...... 298A* Busturia, Ana, ...... 394A Bosco, Giovanni, ..... Opening General Session, Plenary Session II Buszczak, Michael, ...... 134, 580A Bosveld, Floris, ...... 332B* Butcher, Steve, ...... 799A, 801C Botchan, Michael, ...... 798C Buttgereit, Detlev, ...... 182B, 203B Bothma, Jacques, ...... 810C, 830B, 843C* Boulina, Maria, ...... 946A Boutros, Michael, ...... 163A, 251B, 897C, 950B C Box, Kim S., ...... 382A Boyle, Sean M., ...... 73* Cabernard, Clemens, ...... 903C B.P., Arathi, ...... 807C Cabrera, Oscar A., ...... 309C* Brachmann, Carrie, ...... 296B Cady, Amanda, ...... 399C Bradley, Robert K., ...... 840C Cady, Nathaniel, ...... 631A Brady, Regina, ...... 881B Cai, Xiaodong, ...... 938B Bragdon, Meghan, ...... 106, 520A, 826A Call, Gerald B., ...... 783C, 953B Brakken-Thal, Christina, ...... 730A* Callan, Matthew A., ...... 903C* Branco, Alan, ...... 516C Callender, Jenna L., ...... 837C Brasefield, Jessie, ...... 804C Calvi, Brian R., ...... 267C, 292A, 359B Bras-Pereira, Catarina, ...... 738C* Cammarata, Joseph, T., ...... 869B Brás-Pereira, Catarina, ...... 334A Cammarato, Anthony, ...... 461B Bratu, Diana, P., ...... 869B Camp, Darius, ...... 199A* Braun, Alexander, ...... 700A* Campbell, Gerard, ...... 847A Bray, Sarah, ...... 584B, 823A Campbell, Tessa, ...... 595A*, 600C Bremer, Eric, ...... 908B* Campo, Daniel, ...... 511A* Brennan, Elizabeth R., ...... 909C* Campuzano, Sonsoles, ...... 165C, 554B Brennan, Lesley J., ...... 125 Candeias, Rogerio, ...... 136 Brennecke, Julius, ...... 952A Cannon, Rachel, ...... 65 Brenner, S., ...... 836B Cao, Joseph H., ...... 749B* Bricker, Daniel K., ...... 769A* Capovilla, Maria, ...... 770B* Bridges, Lauren, ...... 803B Capri, Michèle, ...... 568A Brill, Julie, 250A Carbone, Mary Anna, ...... 25 Brill, Julie A., ...... 104 Cardona, Norma, ...... 722B Bristow, Chris, ...... 828C Carey, Brandi-lee, ...... 494B Britton, Eric, ...... 329B Carlson, Darby, ...... 508A*, 934A Broadie, Kendal, ...... 411C Carlson, Joe, ...... 946A Brock, Amanda R., ...... 173B* Carlson, John, ...... 685A Broderick, Nichole, ...... 120 Carlson, Joseph, ...... 140 Broderick, Sarah M., ...... 634A* Carlson, Joseph W., ...... 855C* Brodland, G. Wayne, ...... 1 Carlson, Kimberly, ...... 508A, 638B, 934A Brodsky, Michael, ...... 43, 804C Carmine-Simmen, Katia, ...... 434B Brody, Thomas, ...... 719B, 832A, 910A* Carmon, Amber, ...... 873C* Brooks, A. N., ...... 836B Carmona Aldana, Francisco Javier, ...... 555C* Brown, Alayne, ...... 816C Carney, Ginger E., ...... 649A Brown, C. Adam, ...... 931A Caron, Matthieu, ...... 373A Brown, Christopher D., ...... 765C Carr, Thomas, ...... 876C Brown, Daniel L., ...... 382A Carréno, Sébastien, ...... 312C, 321C* Brown, Julie, ...... 403A Carrero-Martínez, Franklin, ...... 728B Brown, Nicholas H., ...... 551B Carroll, Dana, ...... 917B, 919A Brown, Stephen, ...... 46, 212B Carter, Ashley, ...... 512B* Broyer, Risa, ...... 14, 867C*, 870C Carter, Krista, ...... 255C Brückner, Katja,...... 637A 86

Speaker and Author Index

Carthew, Richard W., ...... 849C Chen, Hongtao, ...... 55*, 834C Cartry, Jerome, ...... 12* Chen, H.-S. Vincent, ...... 791B Cartwright, Heather, ...... 83 Chen, Jia, . 828C Cartwright, Heather N., ...... 1 Chen, Jia-Yu, ...... 139 Casanova, Jordi, ...... 216C Chen, Jieyan, ...... 310A* Casares, Fernando, ...... 301A, 738C Chen, Jing, ...... 795C* Casella, George, ...... 487A Chen, Jiong, ...... 174C, 207C, 222C Cash, Amy C., ...... 878B* Chen, Joanna, ...... 152, 333C* Cassidy, Justin J., ...... 849C* Chen, Liang, ...... 32 Casso, David J., ...... 58* Chen, Qian, ...... 211A* Castellanos, Monica C., ...... 671B* Chen, Rebecca, ...... 279C Castilla, Joaquin, ...... 439A Chen, Rui, ...... 805A, 911B Castillo, Ashley, ...... 54 Chen, Sidi, ...... 467B*, 681C* Castillo, Julio Cesar, ...... 619A Chen, Xi, ...... 188B* Catchen, Julian M., ...... 495C Chen, Xiao, ...... 136 Catrina, Irina, E., ...... 869B Chen, Xin, ...... 602B Cavalli, Giacomo, ...... 133, 390C Chen, Xinping, ...... 295A Cavenee, Webster K., ...... 44 Chen, Xu, ...... 726C* Ceballos, Luz, ...... 279C Chen, Yi-Chun, ...... 794B Celik, Arzu, ...... 743B Chen, Yiyun, ...... 805A* Celniker, S., ...... 836B Chen, Yongbin, ...... 200B* Celniker, Susan, ...... 136, 921C, 939C, 946A Chen, Yu-Chan, ...... 769A Celniker, Susan E., ...... 855C Cheng, Chia-hao, ...... 501C Cenci, Giovanni, ...... 351C* Cheng, Haibo, ...... 386B Certel, Sarah J., ...... 694A Cheng, T. C., ...... 422B Cetera, Maureen P., ...... 217A* Cheng, Yan, ...... 355A Cha, Guang-Ho, ...... 456C Cheng, Yim Ling, ...... 545B* Chakrabarti, Sveta, ...... 617B* Cheng, Yuzhong, ...... 816C* Chakravorty, Samya, ...... 647B* Cherbas, Peter, ...... 855C, 928A Chalasani, Uma, ...... 43 Cherezov, Roman, ...... 754A Chalvet, Fabienne, ...... 888C Chernyk, Yaroslava, ...... 406A Chambers, Moria C., ...... 618C* Cherry, Smita, ...... 134 Chan, Chih-Chiang, ...... 134* Cheshire, Alan, ...... 552C Chan, Gina, ...... 277A Chesnokov, Igor N., ...... 266B* Chan, Ho Y. E., ...... 422B* Cheung Chang, Lily S., ...... 107* Chan, Sze Ham, ...... 43 Chia, William, ...... 724A Chan, Tammy P., ...... 773B Chiba, Akira, ...... 728B, 938B, 939C, Chan, W. M., ...... 422B ...... 940A, 941B, 942C, 943A, 944B, 945C, 946A Chandrasekaran, Sriram, ...... 920B Chicanne, Gaetan,...... 321C Chandrasekaran, Vidya, ...... 957C Chichearo, Nicole, ...... 876C Chanet, Soline, ...... 86* Chiolo, Irene, ...... 76*, 369C Chang, Ching-Ho, ...... 482B*, 501C Chiu, Lillian, ...... 335B Chang, Elaine, ...... Plenary Session I Chmielewski, Jeffrey P., ...... 259A* Chang, Henry, ...... 250A Cho, DongYeon, ...... 839B Chang, Hwei-yu, ...... 482B, 501C* Cho, Fong, ...... 553A Chang, Kai Chen, ...... 724A Cho, Janice, ...... 349A Chang, Leo, ...... 74 Cho, Kyoung Sang, ...... 345C Chang, Leo Y., ...... 84* Cho, Si-Chih, ...... 794B Chang, Peter L., ...... 494B Choi, Dae, ...... 715A Chang, Ya-Chu, ...... 440B Choi, Jinkyu, ...... 713B Chang, Yun-Chin, ...... 440B Choi, Jiyoung, ...... 713B Chanut, Helene, ...... 90 Choi, Joan, ...... 412A Chao, Anna, ...... 253A Choi, Kwang-Wook, ...... 675C Chapin, Alex, ...... 863B* Choi, Youngcheol, ...... 713B Charbonnier, Enrica, ...... 818B Choi, Youn-Jeong, ...... 860B* Charng, Wu-lin, ...... 446B Chopra, Vivek, ...... 810C Charng, Wu-Lin, ...... 224B*, 420C Chopra, Vivek S., ...... 112* Charron, Frédéric, ...... 199A Chow, Clement Y., ...... 527B* Chassan, Rachel A., ...... 405C* Christensen, Tim W., ...... 259A, 268A, 365B Chastain, Lerin, ...... 696C Christiansen, Audrey, ...... 198C Chau, Johnnie, ...... 879C* Chromatin Consortium, Drosophila modENCODE, ...... 363C Chaudhary, Varun, ...... 251B* Chu, Dandan, ...... 174C* Chauhan, Chhavi, ...... 895A Chu, Youngmin, ...... 654C Chaves, Cy,...... 546C Chun, Daniel C., ...... 958A Chawla, Geetanjali, ...... 850A* Chung, Hye Jung, ...... 796A Cheatle, Alys, ...... 255C Chung, Jeeyun, ...... 685A Chekunova, Anna I., ...... 523A Chung, Kwanghun, ...... 914B, 933C Chen, Audrey, ...... 668B Chung, Se-Yeon, ...... 546C* Chen, Di, ...... 596B*, 704B Chung, Yundoo, ...... 603C Chen, Geng, ...... 739A* Chung, Yun Doo,...... 718A Chen, Hanqing, ...... 235A, 372C Ciapponi, Laura, ...... 351C 87

Speaker and Author Index

Cichewicz, K., ...... 666C* D Cicin-Sain, Damjan, ...... 753C Clark, Andrew, ...... 28, 34, 513C, 872B Clark, Andrew G., ...... 353B, 527B, 530B Daborn, Phillip, ...... 922A Clark, Courtney M., ...... 468C* Dahal, Giri Raj, ...... 758B Clark, Natalie M., ...... 423C* Dahlstrom, Kurt M., ...... 817A* Clark, Nathaniel L., ...... 486C Dai, Jing, ...... 598A* Cleary, Mike, ...... 722B, 866B Daigle, Joseph G., ...... 425B* Clegg, Robert, ...... 943A Daines, Bryce,...... 805A, 911B* Clough, Emily,...... 590B* Dale, Ryan K., ...... 862A Coffey, Alissa, ...... 459C Dalton, Justin E., ...... 32 Cohen, Jesse, ...... 765C Damm, Vanessa T., ...... 143 Collier, Glen, ...... 484A Daniel, Barbash, ...... 368B Collier, S., ...... 658A Daniels, Joseph, ...... 690C Collier, Simon,...... 159C*, 197B Danis, Peter, ...... 252C Colmenares, Serafin, ...... 369C DasGupta, Ramanuj, ...... 256A Colmenares, Serafin U., ...... 76, 357C* Dauphin-Villemant, Chantal, ...... 472A Combs, Peter A., ...... 923B* Dauwalder, Brigitte, ...... 648C* Comeron, Josep M., ...... 29* David, Gabriela, ...... 224B, 420C, 446B Comet, Itys, ...... 390C Davis, Charles, ...... 159C Concha-Moore, Kirsten, ...... 2 Davis, Claudette P., ...... 413B* Conder, Ryan, ...... 893B Davis, Justin, ...... 484A* Conner, Craig, ...... 715A Davis, Matthew, ...... 797B* Consortium, FlyExpress, ...... 915C Davison, Holly, ...... 74 Conway, Stephen, ...... 459C Dawson, Adam G., ...... 783C Cook, Jodi, ...... 542B Dayal, Dau, ...... 792C Cook, John A., ...... 875B Dean, Derek M., ...... 449B* Cook, Kevin, ...... 931A* Debec, Alain, ...... 311B* Cook, Kevin R., ...... 457A de Bivort, Benjamin, ...... 674B Cook, Kimberley, ...... 931A de Bivort, Benjamin L., ...... 670A, 672C* Cook, Mandy, ...... 424A* Decal, Richard, ...... 255C Cook, Orna, ...... 759C* Decelle, Barbara, ...... 321C Cooley, Lynn, ...... 569B DeDecker, Brian, ...... 80 Coolon, Joseph D., ...... Plenary Session I (continued), 483C* Deery, William J., ...... 645C Cordes, Ethan, ...... 508A, 638B*, 934A Dejean, Sebastien, ...... 615C Core, Leighton J., ...... 112 de Jong, Eiko K., ...... 41 Corona, Davide, ...... 352A Delabaere, Lætitia, ...... 385A Costes, Silvain V., ...... 76 Delvadia, Radha, ...... 433A Cotton, Mathieu, ...... 206B De Maio, Nicola, ...... 929B Cotton, Sean L., ...... 209B Demakov, Sergey A.,...... Plenary Session I (continued) Coughtrey, Dylan, ...... 597C* Demir, Kubilay, ...... 163A Courey, Albert, ...... 844A Denef, Natalie, ...... 87 Courey, Albert J., ...... 749B Deng, Sophie, ...... 938B, 941B, 942C Courtney, Bone, ...... 161B Deng, Sophie T., ...... 940A* Coux, Remi-Xavier, ...... 570C* Deng, Wu-Min, ...... 229A, 299B Cox, Daniel N., ...... 697A, 703A Deobagkar, Deepti D., ...... 383B* Cox, Rachel T., ...... 143* DePace, Angela, ...... 106, 520A, 826A, 833B Cox, Sarah, ...... 204C Depner, Harald,...... 691A Coyle-Thompson, Catherine, ...... 957C De Renzis, Stefano, ...... 195C Cranna, Nicola, ...... 303C Desai, Ridhdhi, ...... 233B* Cranna, Nicola J., ...... 796A* Desai, Siddhi, ...... 389B Cresko, William A., ...... 495C Deshpande, Girish, ...... 593B Crest, Justin M., ...... 2* Des Soye, Benjamin, ...... 821B Cridland, Julie M., ...... 924C* Devido, Sarah, ...... 816C Cripps, Richard, ...... 257B, 407B, 408C, 747C Dhatt, Ravjot, ...... 16 Cripps, Richard M., ...... 827B DiAngelo, Justin, ...... 762C, 876C, 957C Crombach, Anton, ...... 753C Diao, Fengqiu, ...... 709A Crowley, Jacob, ...... 484A Dias, Brian, ...... 70 Crowley, Kelsey, ...... 667A* Di Cara, Francesca, ...... 234C* Crozatier, Michele, ...... 615C Dickson, Barry J., ...... 68, 661A Cruz-Moreno, Beatriz, ...... 622A Dierick, Herman, ...... 642C, 784A Cryderman, Diane E., ...... 343A* DiNardo, Stephen, ...... 884B, 894C Csordás, Gábor, ...... 611B DiNardo, Steve, ...... 880A Culi, Joaquim, ...... 771C* Ding, Tian, ...... 198C Cumenal, Delphine, ...... 888C Dinur, Tama, ...... 593B Currie, Ko, ...... 199A Diop, Soda, ...... 131*, 412A Curtis, Rachel, ...... 479B Dipple, Katrina M., ...... 464B Curtiss, Jennifer, ...... 927C Di Stefano, Luisa, ...... 352A Czech, Benjamin, ...... 952A Distler, Jutta, ...... 565A Djapri, Christine, ...... 669C Dobes, Pavel, ...... 630C 88

Speaker and Author Index

Dobi, Krista C., ...... 557B* Eisen, Michael, ...... 797B, 798C, 838A, 840C, 928A Dobin, Alex, ...... 851B Eisen, Michael B., ...... 108, 114, 515B, 541A, 688A, 923B Dodt, Hans-Ulrich, ...... 565A Ekström, Jens-Ola, ...... 119 Doe, Chris Q., ...... 903C Elcock, Adrian H., ...... 343A Doggett, Karen, ...... 814A Eleftherianos, Ioannis, ...... 619A* Dolan, Claire E., ...... 571A* Elgin, Sarah, ...... 371B Dolezal, Tomas, ...... 450C* Elgin, Sarah C. R., ...... 366C, 381C, 392B, 957C Dombrovsky, Aviv, ...... 770B Elizondo, S., ...... 845B Domingues, Susana, ...... 485B* Ellis, Lisa L., ...... 649A* Dominski, Zbigniew, ...... 272B Ellis, Stephanie J., ...... 175A* Dong, Yi, ...... 958A Emerson, James J., ...... 514A* Donohue, Ryan, ...... 543C Emery, Gregory, ...... 194B, 220A Dopie, Joseph, ...... 133 Emery, Grégory, ...... 312C Dorn, Jonas, ...... 194B Emery, John, ...... 556A Dornhaus, Anna, ...... Plenary Session II Emery, Patrick, ...... 644B Dorus, Steve, ...... 36 Engel, Elodie, ...... 635B Dosey, Timothy, ...... 271A Engie, Liana, ...... 349A Dos Santos, Nicolas, ...... 888C English, Bevin, ...... 597C Dottermusch, Christine, ...... 202A Engström, Ylva, ...... 636C Douglas, Angela E., ...... 623B Enomoto, Masato,...... 5 Dourlen, Pierre, ...... 288C Epstein, Daniel, ...... 787A Dreisewerd, Klaus, ...... 784A Erezyilmaz, Deniz, ...... 529A* Dripps, Isaac, ...... 709A* Erezyilmaz, Deniz F., ...... 31 Driscoll, Katherine, ...... 329B Ericson, Brad, ...... 508A, 934A Dronamraju, Raghuvar, ...... 354C Erives, Albert, ...... 737B, 817A Drummond-Barbosa, Daniela, ...... 890B Erives, Albert J., ...... 912C* Du, Wei, .. 243C, ...... 802A Eskelinen, Sinikka, ...... 616A Dubois, Laurence, ...... 90 Esmaeili, Melody,...... 772A* Dubrovskaya, Veronica, ...... 859A Esparza, A., ...... 845B Dubrovsky, Edward, ...... 859A Esposito, Emilia,...... 810C Dubruille, Raphaëlle, ...... 385A, 644B Esslinger, Stephanie, ...... 761B* Duca, Edward, ...... 77 Esteves, Francisco F., ...... 710B* Duchaine, Jean, ...... 232A Etchegaray, Jon Iker, ...... 294C Duchi, Serena, ...... 193A* Evans, Tim, ...... 692B* Dudoit, S., ...... 836B Evans-Holm, Martha, ...... 140 Duff, M., ...... 836B Duncan, Jason, ...... 606C Dunham, Joseph P., ...... 494B, 510C F Dunipace, Leslie, ...... 846C Dunleavy, Elaine, ...... 344B* Fabian, Lacramioara, ...... 104* Duque, Thyago, ...... 469A* Fabrowski, Piotr, ...... 195C Durham, Mary F., ...... 528C* Fagan, Tiffany, ...... 98 Duronio, Robert, ...... 272B Fagegaltier, Delphine, ...... 851B* Duronio, Robert J., ...... 264C Fairchild, Michael J., ...... 175A Durrin, Sarah, ...... 279C Fan, Yun, ...... 198C, 285C*, 290B Dushay, Mitchell, ...... 908B Fancher, Hailey, ...... 707B Dutta, Pranabananda, ...... 362B Fang, Jianwen, ...... 382A Duttaroy, Atanu, ...... 413B, 781A, 786C Fang, Su, ...... 482B Dyer, Jamie O., ...... 115* Farboodi, Niloofar, ...... 806B* Dyson, Nicholas, ...... 352A* Farkas, Robert, ...... 252C* Dyson, Nicholas J., ...... 110 Fast, Eva, ...... 641B Fast, Eva M., ...... 640A* E Faure, Mathias, ...... 153 Fauvarque, Marie-Odile, ...... 153, 635B* Fedic, Robert, ...... 860B Eade, Kevin, ...... 707B Fedina, Tatyana, ...... 784A Earley, Eric J., ...... 502A* Fedorova, Marina, ...... 185B Early, Angela, ...... 513C* Fehon, Richard, ...... 7, 184A, 338B Eaton, Benjamin, ...... 74 Fehon, Richard G., ...... 249C Eaton, Benjamin A., ...... 84 Feinbaum, Rhonda, ...... 620B Eaton, Douglas C.,...... 954C Feinstein-Rotkopf, Yael, ...... 274A Eberl, Daniel, ...... 683B, 947B Fenckova, Michaela, ...... 450C Eckenrode, Kelly, ...... 106, 520A, 826A Fenton, Tim, ...... 44 Eddy, James A., ...... 920B Fernandes, Ana Clara, ...... 925A* Edery, Isaac, ...... 625A Fernandes, Isabelle, ...... 829A Edgar, Bruce, ...... 900C Fernandes, Isabelle I., ...... 599B* Edgar, Bruce A., ...... 263B Fernandez, Harvey,...... 543C Egorova, Ksenia S., ...... 858C Fernandez-Funez, Pedro, ...... 426C*, 429C, 439A, 937A Ehaideb, Salleh, ...... 51 Fernandez-Valdivia, Rodrigo, ...... 154 Eisen, Arri, ...... 954C Ferrandon, Dominique X., ...... 620B* 89

Speaker and Author Index

Ferrari, Christopher, ...... 574A G Ferree, Patrick M., ...... 358A, 360C, 629B Ferreira, Tania, ...... 323B Ferreira, Tânia C., ...... 572B* Gaeth, Ashley B., ...... 377B Ferrer, Piere, ...... 829A Galko, Michael J., ...... 173B, 682A* Ferrero, Paola, ...... 856A* Gallach Caballero, Miguel, ...... 503B* Field, Amanda, ...... 750C* Gallo, Jacquelyn, ...... 245B Field, Natania, ...... 898A* Gallo, Steven M., ...... 821B Fields, April R., ...... 693C Galloway, J., ...... 658A Findlay, Geoffrey D., ...... 486C* Gammill, Michelle, ...... 279C* Finley, Kim, ...... 776B, 782B* Gandhi, Kevin, ...... 298A Firdaus, Hena, ...... 807C* Ganetzky, Barry, ...... 726C Fischer, Bernd, ...... 950B Gantz, Valentino M., ...... 819C* Fischer, Janice, ...... 231C Gao, Guanjun, ...... 355A Fischer, Wolfgan, ...... 129 Gao, Yang, ...... 737B* Fisher, Bill, ...... 921C Garcia-Alvarez, Gisela, ...... 724A Fisher, Katherine H., ...... 46, 212B* García Fernández, Beatriz, ...... 334A Fisher, Shannon, ...... 710B Garcia-Sanchez, Susana, ...... 621C* Fitzgerald, Kate M., ...... 809B Garrity, Paul A., ...... Plenary Session I Fjeldsted, Courtney, ...... 494B, 511A Garton, Russell, ...... 931A Flaherty, Maria Sol, ...... 902B Gasdaska, Pamela, ...... 272B Flatt, Thomas, ...... 632B Gaspar, Perdo,...... 334A Fleming, Robert J., ...... 225C* Gassaway, Brandon, ...... 758B Flockhart, Ian, ...... 133, 452B Gassert, Rob, ...... 793A Florens, Laurence, ...... 115, 317B, 376A Gates, Julie, ...... 180C Flores, Heather A., ...... 35* Gates, Khalilah L., ...... 40 Foley, Edan, ...... 234C Gatti, Maurizio,...... 350B, 351C Foley, James, ...... 672C Gaudry, Quentin, ...... 672C Forbush, Biff, ...... 656B Gavis, Elizabeth R., ...... 15, 868A Fore, Talor, ...... 137* Gebelein, Brian, ...... 824B Förstemann, Klaus, ...... 761B Geer, Marcus J., ...... 693C Fouillet, Antoine, ...... 288C Gehrett, Abigail, ...... 758B Founounou, Nabila, ...... 313A* Geisbrecht, Erika, ...... 408C Fouquet, Wernher, ...... 691A Gelas, Arnaud, ...... 520A Fowlkes, Charless, ...... 106 Gelfond, Jonathan, ...... 74 Fox, Samuel, ...... 248B Gendron, Patrick, ...... 232A Franc, Nathalie C., ...... 610A* Genetti, Casie,...... 595A Frankel, Nicolas, ...... 31* Geng, Qing, ...... 596B Frasch, Manfred, ...... 565A Gerhold, Abigail R., ...... 326B* Frazer, Kelly, ...... 507C Gerlitz, Offer, ...... 593B* Freel, Christopher, ...... 65 Gerrard, Dave T., ...... 821B Freeman, Marc, ...... 19 Gersten, Merril,...... 507C Fregoso Lomas, Mariana, ...... 731B* Geyer, Pamela K., ...... 78, 377B French, Rachael L., ...... 398B* Gho, Michel, ...... 270C Frise, Erwin, ...... 921C* Giagtzoglou, Nikolaos, ...... 445A Frizzell, Kimberly A., ...... 864C* Giagtzoglou, Nikos, ...... 23*, 226A*, 227B* Frolov, Maxim, ...... 339C* Gibbs, Richard, ...... 25, 928A Fry, Jake,...... 142 Gibbs-Bar, Liron, ...... 274A Frydman, Horacio, ...... 641B Gibson, Greg, ...... 37 Frydman, Horacio M., ...... 640A Gibson, Gregory, ...... 403A Fu, Sheng-Bo, ...... 799A, 801C Gibson, Matthew C., ...... 1 Fuchs, Alisa, ...... 107, 818B* Gibson, William T., ...... 1* Fuentes-Medel, Yuly, ...... 19 Gilbert, Melissa, ...... 8* Fukumoto, Shinya, ...... 628A Gillies, Shane, ...... 315C Fullaondo, Ane, ...... 621C Gilliland, William D., ...... 315C* Fuller, Amy, ...... 254B Gilly, Quentin, ...... 133 Fuller, Margaret T., ...... 600C, 602B Gingeras, Thomas, ...... 851B Fung, Jasmine, ...... 669C Gisselbrecht, S. S., ...... 109 Fung, Karen, ...... 861C Gisselbrecht, Stephen S., ...... 100 Fung, Laura, ...... 553A Gladden, Andrew, ...... 110 Furnari, Frank B., ...... 44 Glatter, Timo, ...... 242B Futschik, Andreas, ...... 929B Glavic, Alvaro, ...... 300C* Fye, Samantha, ...... 727A Gligorov, Dragan, ...... 586A, 820A* Gocha, Tenzin, ...... 801C Godinez, Ryan, ...... 399C Goepfert, Martin, ...... 42 Goldstein, Ann Y. N., ...... 88* Goldstein, Lawrence S. B., ...... Plenary Session I (continued) Gong, Emily, ...... 933C Gonzalez, Arysa, ...... 776B, 782B Gonzalez, Cayetano, ...... 724A 90

Speaker and Author Index

Gonzalez, Ignacio, ...... 829A Haddad, Gabriel, ...... 448A, 465C, 507C Gonzalez, Ines, ...... 90 Haddad1, Gabriel,...... 785B Gonzalez, Inma, ...... 394A Haddad, Gabriel G., ...... 415A Goodall, Ellen, ...... 80 Haddad, Gabriel H., ...... 463A Goodnight, Lindsey, ...... 137 Haden, Thomas N., ...... 559A Goodnight, Lindsey K., ...... 935B Hadi, Boukhatmi, ...... 558C* Gopalakrishnan, Jayachandran, ...... 308B Hadi, Richard S., ...... 668B Gorchakov, Andrey A., ...... 381C Haelterman, Nele, ...... 140 Gouppil, Geraldine, ...... 472A Haenfler, Jill, ...... 160A*, 725B Graham, Patricia, ...... 593B Hafen, Ernst, ...... 144, 242B, 273C, 325A, 342C, 663C Graham, Suzanne, ...... 412A Hafezi, Yassi, ...... 298A Graner, Francois, ...... 332B Hahn, Matthew W., ...... 26, 495C Gravelely, Brenton, ...... Plenary Session I (continued) Haigo, Saori L., ...... 95* Graveley, B. R., ...... 836B* Haimovich, Adrian, ...... 835A Graveley, Brenton R., ...... 483C Hainline, Sarah G., ...... 258C* Gravely, Brenton R., ...... 855C Hakim, Vincent, ...... 829A Graze, Rita M., ...... 487A*, 811A Halaszova, Erika, ...... 252C Greenberg, Anthony J., ...... 530B* Hales, Karen G., ...... 595A, 597C, 600C, 604A Greer, Elisabeth, ...... 253A* Halfon, Marc S., ...... 139*, 247A, 821B*, 909C Gregoire, Isabel, ...... 153 Hall, Sonia, ...... 161B* Gregor, Dawn, ...... 245B Haller, Samantha, ...... 620B Gregor, Thomas, ...... 732C Hallermann, Stefan, ...... 691A Grevengoed, Elizabeth, ...... 812B Hallman, Mikko,...... 616A Grewal, Savraj, ...... 3 Haltaufderhyde, Kirk, ...... 574A Grewal, Savraj S., ...... 132, 302B, 778A Haltiwanger, Robert S., ...... 154 Gribskov, Michael, ...... 113 Hama, Chihiro, ...... 650B Griemert, Barbara, ...... 203B Hamaratoglu, Fisun, ...... 59* Griffith, Leslie,Opening General Session, Plenary Session I, 679A Hamdy, Freddie, ...... 47 Grillo-Hill, Bree, ...... 45* Hammonds, Ann, ...... 921C, 946A Grimm, Oliver, ...... 208A Han, Sangmi, ...... 713B Grive, Kathryn, ...... 375C Han, Yi, ...... 25 Grönholm, Juha, ...... 150 Handler, Dominik, ...... 952A Gross, Julia, ...... 251B Hannan, Ross, ...... 796A Grosshans, Jörg, ...... 62 Hannon, Gregory, ...... 952A Groth, Verena, ...... 202A* Hanover, John A., ...... 774C Groves, Hillary, ...... 226A Hansen, Curtis J., ...... 912C Gstaiger, Matthias, ...... 242B, 325A Hansen, Malene, ...... 790A Gu, Tingting, ...... 366C Haralalka, Shruti, ...... 83 Gu, Ying, ...... 699C Harbour, Lacey, ...... 788B* Guan, Xue Li, ...... 240C Harden, Nicholas, ...... 188B, 706A, 893B Guarner, Ana, ...... 745A* Hardin, Aaron, ...... 515B* Gubb, David, ...... 614B, 621C Hariharan, Iswar, ...... 298A, 326B Guenier, Anne-Sophie, ...... 232A Harini, Ballagere P., ...... 539B* Guerrero, Paola A., ...... 75* Harlan, Amber L.,...... 913A* Guichard, Annabel E., ...... 622A* Harpaz, Nofar, ...... 549C* Guichet, Antoine, ...... 311B Harris, Harriet L., ...... 125* Guild, Gregory, ...... 556A Harris, Nathan J., ...... 162C* Guilgur, Leonardo, ...... 323B Harrison, Douglas, ...... 211A, 215B Guirao, Boris, ...... 332B Harrison, Douglas A., ...... 214A, 579C Guittard, Émilie, ...... 472A Harrison, Milissa, ...... 798C Gunawardena, Shermali D., ...... 416B*, 727A*, 727A Harsh, Sneh, ...... 400A Gunnell, Taylor, ...... 595A Harshman, Lawrence, ...... 530B Guntermann, Silvia, ...... 124* Hartl, Daniel, ...... 493A, 516C Gupta, Indrani, ...... 932B* Harvey, Kieran F., ...... 4* Gupta, Ram Prakash, ...... 400A Hasanuddin, Harrison, ...... 669C Gupta, Vineet, ...... 938B Hassel, Christiane A., ...... 267C* Gurbich, Tatiana A., ...... 488B* Hatch, Martin, ...... 399C Gururaja Rao, Shubha, ...... 77 Hatori, Ryo, ...... 57, 168C, 550A*, 733A Gutiérrez, Lucia, ...... 391A Haucke, Volker, ...... 705C Gvozdev, Vladimir A., ...... 858C Haueter, Claire, ...... 23, 67, 420C, 445A, 446B Gygi, Steven, ...... 136 Havko, Nathan, ...... 605B Hawley, R. Scott, ...... Opening General Session, 316A, 317B Haynes, J. K., ...... 954C H He, Bin, ...... 489C* He, Bing, ...... Plenary Session II, 78 He, Cuiwen, ...... 669C Ha, Nati,297C He, Li, ...... 91* Ha, Tal Soo, ...... 24 He, Xin, ...... 469A Haberman, Adam, ...... 52 He, Yuchun, ...... 140 Haberman, Adam S., ...... 787A* Healy, Lindsey, ...... 130 Hackett, Sean R., ...... 530B Heberlein, Ulrike, ...... 398B 91

Speaker and Author Index

Heck, Jennifer, ...... 903C Hu, Claire, ...... 133 Heck, Margarete M. S., ...... 77*, 110 Hu, Claire Y., ...... 452B* Heffer, Alison, ...... 470B* Huang, Hai, ...... 235A, 372C* Heidari, Paniz, ...... 783C* Huang, He, ...... 785B* Heine, Holger, ...... 453C, 639C Huang, Jerry, ...... 55, 834C Helander, Lynda, ...... 257B Huang, Jianhua, ...... 780C Helenius, I. Taneli, ...... 40 Huang, Juan, ...... 171C Helfand, Stephen, ...... 763A Huang, Ming-Hao, ...... 794B Hemmerle, Dawn M., ...... 953B* Huang, Xun, ...... 281B, 608B Henderson, Laura, ...... 259A Huang, Yaling, ...... 18 Hendren, Jill, ...... 257B Huang, Yan, ...... 704B Hendrix, David A., ...... 112 Huang, Yi-Chun, ...... 229A Hengenius, James, ...... 113 Huang, Ying, ...... 570C Henikoff, Jorja, ...... 356B Huang, Yu Fen, ...... 701B* Henikoff, Steven, ...... 356B Huber, Wolfgang, ...... 950B Henrich, Vincent C., ...... 837C* Hudson, Alicia, ...... 881B Hercegova, Alena, ...... 252C Hughes, Stacie E., ...... 316A* Hernáiz-Hernándeza, Yainna, ...... 56 Hulselmans, Gert-Jan, ...... 925A Hernandez, Ana M., ...... 789C* Hultmark, Dan, ...... 119, 609C, 616A Hernández, Rosario, ...... 165C, 554B Humphreys, Gregory B., ...... 189C*, 190A Hetie, Phylis, ...... 889A* Hung, Wan-Tzu, ...... 440B Hiatt, Mary Alice, ...... 367A Hunter, Chad M., ...... 268A* Hiesinger, P. Robin, ...... 134, 210C, 787A Hunter, Henry C., ...... 857B* Hilgers, Valerie,...... 751A* Hursh, Deborah, ...... 275B Hill, Olivia, ...... 822C* Hursh, Deboroh, ...... 286A Hipfner, David R., ...... 176B* Hwang, Helen J., ...... 17* Hirsh, J., ...... 666C Hwang, Soojin, ...... 345C Ho, Xuyen M., ...... 88 Hyrsl, Pavel, ...... 630C Hochmuth, Christine E., ...... 904A* Hoekstra, Luke A., ...... 38* Hofman, Ariel, ...... 665B I Hogan, J., ...... 658A Hogan, Justin, ...... 159C Iafe, Timothy, ...... 12, 566B Hohl, Amber M., ...... 377B Ibar, Consuelo, ...... 300C Hojoong, Kwak,...... 368B Iché-Torres, M., ...... 666C Holderbaum, Laura, ...... 951C, 952A Igaki, Tatsushi, ...... 5 Holloway, Alisha K., ...... 491B Ihry, Robert, ...... 111* Holloway, David M., ...... 752B*, 755B Iketani, Ashley M., ...... 248B* Holm, Åsa, ...... 636C Ikura, Mitsuhiko, ...... 233B Holmbeck, Marissa, ...... 27, 763A Inamdar, Arati, ...... 425B Holmbeck, Marissa A., ...... 451A* Inamdar, Arati A., ...... 428B* Holub, Natalia, ...... 406A* Inoue, Yoshiko,...... 551B* Holub, Olena, ...... 406A Ip, Y.Tony, ...... 886A Hong, Eugenie S., ...... 349A Isabel, Guillaume, ...... 69 Hong, Minh, ...... 694A Ishimoto, Hiroshi, ...... 660C* Hong, Wanjin, ...... 4 Ishio, Akira, ...... 57, 156*, 223A, 733A Hong, Xiaojing, ...... 947B Ishiyama, Noboru, ...... 233B Hong, Yang, ...... 171C Islam, Abul, ...... 339C Hong, Yoon Ki, ...... 345C* Ismat, Afshan, ...... 552C* Honti, Viktor, ...... 611B* Ito, Hiroki, ...... 650B* Hoover, Heather, ...... 129 Ito, Kei, ...... 69 Horabin, Jamila,...... 346A Ives, Sarah, ...... 282C Hori, Kazuya, ...... 228C* Ivey, Lauren E., ...... 600C* Horn, Lucas A., ...... 612C* Iyengar, Balaji G., ...... 553A* Horn, Sarah, ...... 65 Iyer, Eswar P. R., ...... 697A, 703A* Horn, Thomas, ...... 950B* Iyer, Srividya Chandramouli, ...... 697A*, 703A Hornbruch, Christina, ...... 203B* Horne-Badovinac, Sally, ...... 96, 217A Horu, Katzuya, ...... 225C J Hoskins, Roger, ...... 140 Hou, Lin .. , ...... 64 Hou, Steven, ...... 895A, 901A J., Mohan, ...... 807C Houle, David, ...... 471C*, 538A Ja, William, ...... 775A Hourmozdi, Jonathan N., ...... 26 Jacobs, Julie, ...... 683B*, 947B* Housden, Ben, ...... 823A* Jaeger, Johannes, ...... 753C* Houwing, Saskia, ...... 105* Jaeger, S. A., ...... 109 Howard, Dagnie C., ...... 358A* Jafari, Mahtab, ...... 532A Howick, Virginia M., ...... 623B* Jafar-Nejad, Hamed, ...... 154, 230B Hoxha, Valbona, ...... 648C Jaffari, Shadi, ...... 118 Hsu, Hwei-Jan, ...... 890B* Jagge, Christopher, ...... 690C Hsu, Tun-Chieh, ...... 427A* Jährling, Nina,...... 565A 92

Speaker and Author Index

Jain, Roshan A., ...... 15 K Jaiswal, Manish, ...... 224B, 420C, 446B Jan, Lily, ...... 18 Jan, Yuh Nung, ...... 18 Kaczynski, Tadeusz J., ...... 727A Jan, Yun Nung, ...... 651C Kadaba, Madhura, ...... 359B* Jang, Hyo-sik, ...... 811A Kadandale, Pavan, ...... 149 Jang, Jennifer, ...... 668B Kadlec, Lisa, ...... 957C Janiszewski, Michal M., ...... 77 Kadlec, Lisa A., ...... 245B* Jankovics, Ferenc, ...... 611B Kadrmas, Julie L.,...... 177C* Janody, Florence, ...... 334A*, 738C Kaercher, Leah, ...... 417C Jaramillo, Carmelita, ...... 407B*, 747C Kagesawa, Tatsuo, ...... 938B, 941B*, 942C* Jasper, Heinrich, ...... 899B, 904A Kagey, Jacob Daniel, ...... 954C* Jauregui, Milu, ...... 250A Kague, Erika, ...... 710B Jawaid, Adeel, ...... 224B, 420C, 446B Kahn, Tatyana G.,...... 81 Jayanandanan, Nair, ...... 186C Kain, James, ...... 672C, 674B* Jayasurya, Karthik, ...... 815B Kaiser, Vera B., ...... 490A* Jean, Steve, ...... 204C* Kalderon, Daniel, ...... 898A Jean-louis, Frendo, ...... 558C Kale, Abhijit T., ...... 287B* Jeffreys, Charlotte A., ...... 318C Kalifa, Yossi, ...... 274A, 593B Jeffries, Neal, ...... 100, 835A Kallio, Jenni, ...... 150 Jen, Joanna C., ...... 669C Kallsen, Kimberley, ...... 453C* Jenkins, Victoria, ...... 279C Kalra, Bhawna, ...... 525C, 792C* Jennens, Joanna M., ...... 130* Kamiyama, Daichi, ...... 938B, 943A*, 944B Jenny, Andreas, ...... 163A* Kang, Jongkyun, ...... 675C* Jensen, Kurt, ...... 429C*, 439A Kang, Kyeongjin, ...... Plenary Session I Jeskey, Craig, ...... 329B Kang, Min J., ...... 727A Jezowska, Barbara, ...... 334A Kang, Min-Ji, ...... 66* Jhai, Bo, ...... 136 Kang, Yunsik, ...... 280A*, 282C Jhangiani, Shalini, ...... 928A Kango-Singh, Madhuri, ...... 306C, 734B Ji, Jun-Yuan, ...... 803B Kanodia, Jitendra, ...... 914B* Ji, Shuiwang, ...... 748A Kanodia, Jitendra S., ...... 933C Jia, Dongyu, ...... 229A* Kanuka, Hirotaka,...... 628A Jia, Jianhang, ...... 200B Kao, Joyce, ...... 511A Jiang, Huabei, ...... 936C Kaplan, Elena, ...... 700A Jiang, Jianqiao, ...... 814A Kaplan, Tommy, ...... 798C, 838A*, 840C Jiang, Jin, ...... 200B, 886A Kaplan, Yosef, ...... 274A Jiang, Larry, ...... 803B Kapun, Martin, ...... 521B Jiang, Lichun, ...... 926B* Kapur, Megha, ...... 255C Jiang, Pan-Pan, ...... 516C Kapuria, Subir, ...... 899B* Jiao, Renjie, ...... 235A*, 372C Karamsetty, Madhu, ...... 697A, 703A Jimenez, Erin, ...... 594C* Karch, François, ...... 586A, 820A Jiménez, Gerardo, ...... 809B Karlsson, Daniel, ...... 695B, 723C Jimenez-Vidal, Maite, ...... 45 Karpac, Jason, ...... 899B Jin, Shan, ...... 716B Karpen, Gary, ...... 344B, 369C, 375C Jo, Juyeon, ...... 682A Karpen, Gary H., ...... 76, 357C, 366C, 381C Johnson, Aaron N., ...... 559A*, 560B* Karpowicz, Philip, ...... 952A Johnson, Justine E., ...... 79 Karr, Timothy, ...... 36*, 748A Johnson, Neil, ...... 938B Kaschube, Matthias, ...... Plenary Session II, 89 Johnson, Oralee, ...... 72 Kasprowicz, Jaroslaw, ...... 925A Johnson, Tamara, ...... 567C Kassis, Judith, ...... 816C Johnson, Wayne A., ...... 673A* Kataoka, Hiroshi, ...... 472A Joliot, Alain, ...... 237C Kathuria, Hitesh,...... 948C* Jonathan, Enriquez, ...... 558C Kaufman, Thomas, ...... 931A Jones, Christopher, ...... 957C Kaur, Amandeep, ...... 700A Jones, Corbin D., ...... 502A Kavlie, Ryan, ...... 683B Jones, Gabriel P., ...... 795C, 875B Kawakatsu, Yasuhiro, ...... 57 Jones, Leanne, ...... 128, 589A Kay, David, ...... 331A Jones, Richard, ...... 389B Kazemian, Majid, ...... 139 Jones, Tiffani A., ...... 583A* Keebaugh, Erin S., ...... 624C* Jones-Hackathorne, Amber, ...... 155 Keegan, Liam, ...... 430A Jourjine, Nicolas, ...... 27 Keleman, Krystyna, ...... 41, 661A Joyce, Eric, ...... 384C* Keleman, Krystyna M., ...... 68* Juárez, Rafael, ...... 391A Kelleher, Erin S., ...... 10* Jud, Molly C., ...... 190A* Keller, Lena M., ...... 268A Judd, Seth M., ...... 783C Kelley, Richard, ...... 82, 916A Jung, David, ...... 958A Kellis, Manolis, ...... 136, 828C Jung, Youngsook L., ...... 366C Kellum, Rebecca, ...... 346A Kelly, Seth M., ...... 954C Kelsey, Keegan J., ...... 353B* Kelstrup, Hans C. P., ...... 505A Kendig, Ashley, ...... 874A* 93

Speaker and Author Index

Kennedy, Alvin,...... 219C Konikoff, Charlotte, ...... 748A Kennedy, Brian, ...... 460A Kopp, Artyom, ...... 474C, 478A, 479B, 735C, 928A Kennedy, Cameron, ...... 357C, 369C, 381C Korbel, Lindsey J., ...... 693C Kennell, Jennifer A., ...... 853A, 955A* Kornberg, Thomas, ...... 58 Kerr, Kimberly S., ...... 19* Kornbluth, Sally, ...... 65, 276C Keshishian, Haig, ...... 656B Kornfeld, Hannah W., ...... 360C* Keshishyan, Tatevik, ...... 279C Korthauer, Laura E., ...... 578B Keunen, Sabine, ...... 925A Koryakov, Dmitry, ...... 364A Kevorkian, Sara, ...... 460A, 605B Korzelius, Jerome P., ...... 263B* Khammari, Asma, ...... 293B Kose, Hiroyuki,...... 601A* Khan, Sumbul J., ...... 400A* Kosiol, Carolin, ...... 929B Khan, Zia, ...... 89 Kotadia, Shaila R., ...... 322A* Khanna, Mansi R., ...... 178A* Kotov, Alexei A., ...... 858C Kharazmi, Jasmine, ...... 808A* Kotzebue, Roxanne, ...... 776B*, 782B Kharchenko, Peter V., ...... 366C, 381C Kovacs, Jennifer, ...... 540C Khurana, Jaspreet S., ...... 11* Kovalick, Gae, ...... 788B Khurana, Parul, ...... 948C Koyama, Takashi, ...... 314B* Khurana, Sukant, ...... 399C Kozlov, Konstantin, ...... 756C Kibanov, Mikhail V., ...... 858C* Krahn, Michael P., ...... 164B*, 205A* Kiger, Amy, ...... 149, 185B, 196A, 204C, 410B Kramer, Daniela, ...... 41 Killip, Lauren E., ...... 3* Kramer, Helmut, ...... 52 Kim, Ayoung, ...... 713B Krämer, Helmut, ...... 250A Kim, Darae, ...... 345C Kramer, Jamie M., ...... 41* Kim, Jane, ...... 63 Krantz, David E., ...... 437B, 668B, 669C Kim, Jonggil, ...... 713B Kravarik, Kellie, ...... 254B* Kim, Maria, ...... 380B, 381C Kravchuk, Oksana, ...... 380B Kim, Maria V., ...... 918C* Kravitz, Edward, ...... 784A Kim, Miahcel, ...... 945C Kreitman, Martin, ...... 489C Kim, Michael, ...... 938B, 941B, 942C Kreko, Tabita, ...... 74 Kim, Michael D., ...... 698B Kremer, Stefanie, ...... 816C Kim, Myung Jun, ...... 673A Kretzschmar, Doris, ...... 421A, 424A, 434B Kim, Ryan, ...... 927C Krieger, Charles, ...... 706A Kim, Sang Hoon, ...... 684C* Krieser, Ronald, ...... 65 Kim, Wontae, ...... 713B* Krishnan, Harish, ...... 374B Kim, Woo Jae, ...... 651C* Krishnan, Kadalmani, ...... 136 Kim, Yoosik, ...... 208A, 246C, 809B*, 914B, 933C* Kronen, Maria R., ...... 145 King, Elizabeth G., ...... 531C* Kronert, William A., ...... 172A, 461B King-Jones, Kirst, ...... 234C, 764B*, 806B Kronhamn, AnnaKarin, ...... 119 Kirchhausen, Tom, ...... 228C Kronhamn, Jesper, ...... 119*, 609C Kirilly, Daniel, ...... 699C Kruettner, Sebastian, ...... 68, 661A* Kirov, Nikolai, ...... 799A, 801C Krupa, Bradlee, ...... 498C Kirsanov, Kirill I., ...... 340A* Krupinski, Thomas, ...... 40 Kiselev, Alexander V., ...... 236B* Ku, Hsueh-Yen, ...... 9 Kislukhin, Galina, ...... 532A* Kuang, Chaoyuan, ...... 885C* Kitamoto, Toshihiro, ...... 660C Kucherenko, Mariya, ...... 454A* Kittel, Robert, ...... 691A Kucherenko, Mariya M., ...... 42 Klämbt, Christian, ...... 702C Kuebler, Daniel R., ...... 417C* Klein, Benjamin, ...... 508A Kuhl, Zachery, ...... 159C Klein, Hayley, ...... 226A Kuklin, Elena, ...... 679A Klein, Jason, ...... 958A Kumar, Justin, ...... 744C Klein, Michael W., ...... 377B Kumar, Justin P., ...... 742A Kleino, Anni, ...... 609C, 616A Kumar, Sudhir, ...... 748A, 915C* Kleinsorge, Sarah E., ...... 573C* Kundu, Mukta, ...... 719B*, 832A, 910A Klepzig, Annekatrin, ...... 146* Kunttas Tatli, Ezgi, ...... 255C* Kneeland, Thomas, ...... 732C Kuo, Tsung-Han, ...... 784A* Knight, Charniece, ...... 762C Kuo, Tzu-Hsing, ...... 676A* Kobey, Robert L., ...... 793A* Kupara, Kudakwashe L., ...... 396C* Kochinke, Korinna, ...... 41 Kupinski, Adam, ...... 148 Kocks, Christine, ...... 616A, 620B Kurciyan, Adrianne, ...... 622A Koehler, Katja, ...... 663C Kuroda, Junpei, ...... 57* Kofler, Robert, ...... 521B, 929B Kuroda, Mitzi I., ...... 381C Koganezawa, Masayuki, ...... 650B Kuroda, Mitzi K., ...... 366C Koh, Tong-Wey, ...... 685A* Kurtz, Irina, ...... 271A Koh, Youngho, ...... 713B Kurucz, Éva, ...... 611B Köhler, Katja, ...... 273C Kusch, Thomas, ...... 373A* Kohlmaier, Alexander, ...... 900C Kuthethur, Guruharsha, ...... 136, 946A Kok, Kurtulus, ...... 842B Kuzin, Alexander, ...... 719B, 832A, 910A Kolesnikova, Tatyana, ...... 364A Kuzin, Boris, ...... 754A Kolodkin, Alex L., ...... 699C Kwak, Su-Jin, ...... 414C* Komori, Hideyuki, ...... 141 Kwan, Elena, ...... 353B Kondo, Shu, ...... 260B* Kwok, Ben, ...... 758B 94

Speaker and Author Index

Kwon, Young, ...... 684C Lee, So Young, ...... 621C Kwong, Pak, ...... 844A* Lee, Tom,...... 230B* Lee, Tzumin, ...... 18 Lee, Wendy, ...... 152 L Lee, Young-Ha, ...... 456C Lee, Youngseok, ...... 684C Lee Jue Er, Amanda, ...... 796A LaBeau, Elisa, ...... 408C* Lefrançois, Martin, ...... 232A LaFlamme, Brooke A., ...... 103* Legard, Jillian, ...... 271A Laflamme, Carl, ...... 194B* Lehmann, Ruth, ...... 97, 105, 570C Lafont, René, ...... 472A Lei, Elissa P., ...... 862A LaFrance, Russell, ...... 757A Lei, Zhou, ...... 277A Lagha, Mounia, ...... 810C* Leiblich, Aaron, ...... 47 Lai, Eric, ...... 256A Leips, Jeff, ...... 528C, 612C Lai, Eric C., ...... Plenary Session II Leiserson, William M., ...... 656B* Lai, Wi, ...... 860B Lemaitre, Bruno, ...... 120, 617B Laimer, Hannah, ...... 245B Lemieux, Sébastien, ...... 232A Lakhotia, Subhash, ...... 330C Lemmon, Vance, ...... 938B, 940A Lakshmi, G. Girija, ...... 795C, 875B* Lemos, Bernardo, ...... 493A, 516C* Lallet, Sylvie, ...... 250A Lenartowska, Marta, ...... 606C Lama, Chamala, ...... 648C Leonard, Caron, ...... 181A Lamarre, Daniel, ...... 232A Leonardi, Jessica, ...... 154*, 230B Landais, Severine, ...... 589A* Leptin, Maria, ...... 186C, 544A Landeen, Emily, ...... 542B Leroy, Jacqueline,...... 888C Landolin, J., ...... 836B Leser, Katja, ...... 602B* Lang, Michael, ...... 472A* Lesovaya, Ekaterina A., ...... 340A Langley, Charles H., ...... 491B, 519C Letsou, Anthea, ...... 189C, 190A Langley, Sasha, ...... 357C Leung, Aileen, ...... 279C Lao, Tingjia, ...... 473B*, 477C Leung, Wilson, ...... 957C Laplante, Caroline, ...... 179B Levens, David, ...... 303C, 796A Larsen, Ellen, ...... 746B Levet, Clémence, ...... 288C* Larson, Kimberly, ...... 757A Levine, Michael, ...... 112, 138, 751A, 810C, 843C Latapie, Yvan, ...... 90, 829A Levine, Mike, ...... 830B Lattao, Ramona, ...... 350B Levis, Bob,...... 140 Lau, K. F., ...... 422B Lewellyn, Lindsay K., ...... 96* Laurence, Dubois, ...... 558C Lewenza, Shawn, ...... 121 Laver, John D., ...... 861C* Lewis, John, ...... 553A Lavoie, Hugo, ...... 232A Lewis, Sarah, ...... 760A Lawal, Hakeem O., ...... 437B, 668B* Li, Changqing, ...... 235A, 372C Lawson, Jermaine, ...... 700A Li, Fang, ...... 494B Layalle, Sophie, ...... 237C* Li, Guangyao, ...... 379A Layana, Carla, ...... 856A Li, Huabing, ...... 381C Layne, Jessica, ...... 159C Li, Hua-Bing, ...... 378C* Lazzaro, Brian P., ...... Plenary Session I, 122, 623B Li, Hui, ...... 346A Le, Stephanie, ...... 27 Li, H. Y., ...... 422B League, Garrett P.,...... 740B* Li, Jinghong, ...... 757A Learte, Anabel R., ...... 165C* Li, Li M., ...... 842B Leatherman, Judith L., ...... 880A* Li, Qingyun, ...... 24*, 711C Leblanc, Benjamin, ...... 390C Li, Renhua, ...... 504C*, 839B, 926B Le Borgne, Roland, ...... 206B*, 250A, 313A Li, Sharon, ...... 63 Lecland, Nicolas, ...... 311B Li, Shuang,...... 200B Lee, Amanda, ...... 303C Li, Tiffany,...... 728B*, 938B Lee, Byeo Ri, ...... 183C Li, Tongchao, ...... 227B Lee, Chang Hyun,...... 238A* Li, Wenke, ...... 399C Lee, Cheng-Yu, ...... 141*, 160A, 725B, 885C Li, Willis, ...... 362B Lee, Daeweon, ...... 713B Li, Willis X., ...... 361A*, 757A Lee, Dahye,...... 456C Li, Xianghua, ...... 430A* Lee, Dong-Seok, ...... 626B Li, Xiaolei, ...... 374B* Lee, Grace Y. C., ...... 491B* Li, Xiao-Yong, ...... 515B, 798C*, 838A, 840C Lee, Jack J., ...... 15, 868A* Li, Xiazhen, ...... 598A Lee, Janice, ...... 620B Li, Xin H., ...... 716B Lee, Jeongmi, ...... 718A* Li, Yi-Dong, ...... 154 Lee, Jung-Eun, ...... 625A* Li, Yuanli, ...... 648C Lee, Kyu-Sun, ...... 414C, 626B* Li, Yuhong, ...... 295A Lee, Laura A., ...... 60, 93, 258C Li, Yumei, ...... 805A, 911B Lee, Min Jung, ...... 345C Li, Zhihong, ...... 446B Lee, Richard E., Jr., ...... 517A Li, Zhihuan, ...... 327C* Lee, Seung-Kyu, ...... 178A Lian, Tianshun, ...... 708C Lee, Seung-kyu, ...... 166A* Liang, Hsiao-Lan, ...... 799A*, 801C Lee, Sihyeock, ...... 713B Liang, Xuehong, ...... 235A, 372C Lee, Soojin,...... 345C Liao, Kuo-An, ...... 409A* 95

Speaker and Author Index

Liebl, Eric C., ...... 693C*, 956B* Lundin, Erika, ...... 695B, 723C Lightcap, Samantha, ...... 604A Luo, Dion, ...... 800B* Li-Kroeger, David, ...... 824B* Luo, Hong, ...... 720C* Lim, Chiat Koo, ...... 82* Luo, Jun, ...... 207C* Lim, Edwin, ...... 699C Luo, Liqun, ...... 681C Lim, Su Jun, ...... 362B* Lusk, Richard W., ...... 108* Lim, Young-Mi,...... 305B, 431B*, 712A Lynch, Brian T., ...... 693C Lima, Chris, ...... 595A Limmer, Stefanie, ...... 620B Lin, Haifan, ...... 9, 94 M Lin, Nianwei, ...... 379A*, 936C Lin, Ran, ...... 127* Ma, Jun, ...... 235A Lin, Yong Qi, ...... 23, 67 Ma, Lijia, ...... 828C Lincoln, Tracey A., ...... 871A* Ma, Xue H., ...... 716B Linder-Basso, Daniela, ...... 381C Ma, Zhiguo, ...... 281B, 608B Lindsay, Alison,...... 335B MacAlpine, David, ...... 63 Lindsay, Scott, ...... 613A* MacAlpine, David M., ...... 359B Linford, Nancy J., ...... 773B* MacDonald, Ryan, ...... 695B, 723C Ling, Jinli, ...... 644B* Macdonald, Stuart J., ...... 531C, 533B*, 534C, 535A, 536B Linz, David M., ...... 517A* MacDonald, Warren, ...... 852C Lipshitz, Howard, ...... 861C MacElvany, Benjamin, ...... 133 Lipsick, Joe, ...... 689B Machone, Joshua F., ...... 913A Lis, John T., ...... 112 MacIntyre, Ross, ...... 873C Little, Shawn C., ...... 732C* Mackay, Trudy,...... 25 Liu, Feng, ...... 825C* Mackay, Trudy F. C.,...... 678C Liu, Hsiao-Yun, ...... 801C Macleod, Gregory, ...... 74 Liu, Hsiu-Yu, ...... 432C* Maddox, Paul, ...... 194B Liu, Jiandong, ...... 566B Maeda, Reo, ...... 57, 168C*, 550A, 733A, 949A Liu, Ji-Long, ...... 575B, 854B Maeda, Robert, ...... 586A, 820A Liu, Jun, ...... 748A Maeng, Oky, ...... 456C* Liu, Kai, ...... 295A* Maggert, Keith, ...... 75, 347B, 396C Liu, Lei, ...... 64, 295A Magico, Adam, ...... 764B Liu, Li, ...... 94* Magliarelli, Helena de Fatima, ...... 454A Liu, Lu-Ping, ...... 952A Magliocco, Joe, ...... 843C Liu, Luping, ...... 951C Maheshwari, Shamoni, ...... 30* Liu, Na, ...... 9 Mahoney, Rebekah, ...... 74 Liu, Raymond, ...... 187A Mahowald, Anthony, ...... 600C Liu, Shixuan, ...... 266B Maiato, Helder, ...... 311B Liu, Tao, ...... 185B Main, Bradley J., ...... 811A* Liu, Wenke, ...... 720C Maini, Philip K., ...... 331A Liu, Yajuan, ...... 200B Majumder, Pralay, ...... 218B* Liu, Yingfang, ...... 266B Makhijani, Kalpana, ...... 637A* Liu, Zhi H., ...... 716B Mäkinen, Leena, ...... 150 Liu, Zhihua, ...... 704B* Malagon, Nicolas, ...... 746B* Liu, Zhonghua, ...... 281B* Malik, Harmit, ...... 367A, 492C Lloyd, Alexander R., ...... 912C Malmanche, Nicolas, ...... 261C, 311B Lohmann, Ingrid, ...... 297C Malone, John, ...... 34, 926B Long, Anthony, ...... 532A Malone, John H., ...... 480C, 504C, 839B* Long, Anthony D., ...... 510C, 531C Mamsa, Hafsa, ...... 669C Long, Jenny, ...... 183C, 455B* Manak, John, ...... 799A, 801C Long, Manyuan,...... 33, 467B, 681C Manak, J. Robert, ...... 51* Longdon, Ben, ...... 627C Manivannan, Sathiya, ...... 760A Longworth, Michelle S., ...... 110* Manjón, Cristina, ...... 745A Lopes, Francisco JP, ...... 752B, 755B Manning, Alyssa J., ...... 85* Lopez-Bigas, Nuria, ...... 339C Manning, Lathiena, ...... 219C* Loppin, Benjamin, ...... 385A* Marais, Gabriel, ...... 385A Loschky, Sophia S., ...... 535A Mardon, Graeme, ...... 911B Lott, Susan E., ...... 114*, 923B Marenda, Daniel, ...... 435C Lovato, Candice, ...... 257B Marenda, Daniel R., ...... 20*, 433A Love, Dona C., ...... 774C Marinho, Joana, ...... 301A* Low, Boon Chuan, ...... 699C Markow, Therese, ...... 518B Loyer, Nicolas, ...... 206B Markow, Therese A., ...... Plenary Session II Lu, Beika, ...... 686B* Marks, Hendrik, ...... 41 Lu, Hang, ...... 914B, 933C Márkus, Róbert, ...... 611B Lu, Hsiang-Chih, ...... 224B Marmion, Rob, ...... 191B* Lu, Jian, ...... 872B* Márquez, Eladio, ...... 471C Lu, Qiuheng, ...... 167B* Marquez, Jhomar E., ...... 292A Lu, Yong, ...... 470B Marr, David, ...... 245B Lu-Bo, Ying, ...... 785B Marriage, Tara N., ...... 534C* Luecke, David, ...... 474C* Marrone, April, ...... 454A Lum, Thomas E. C. H.,...... 813C 96

Speaker and Author Index

Marrone, April K., ...... 42* Mendoza, Carlisdania, ...... 335B* Marsden, Luke, ...... 47 Menezes, Bianca, ...... 466A Marshall, Lynne, ...... 132, 302B* Menezes, Bianca F., ...... 652A* Martin, Adam C., ...... Plenary Session II Menezes-Cabral, Sofia, ...... 6* Martin, Tara, ...... 106 Mengoli, Valentina, ...... 350B Martin, Tara L., ...... 826A* Menoret, Delphine, ...... 829A Martin-Blanco, Enrique, ...... 736A Mentelova, Lucia, ...... 252C Martín-Blanco, Enrique, ...... 6 Merkes, Chris M., ...... 533B Martinho, Rui, ...... 572B Merkle, Julie A., ...... 60* Martinho, Rui G., ...... 323B*, 323B Merritt, Thomas, ...... 276C Maruyama, Rika, ...... 812B* Merritt, Thomas J. S., ...... 813C* Marzluff, William,...... 272B Mertel, Sara, ...... 691A* Maschat, Florence, ...... 237C Metzger, Thomas J., ...... 564C Masly, John P., ...... 32*, 935B Metzstein, Mark M., ...... 548B, 583A, 863B, 864C, 865A Mason, Grace A., ...... 827B* Meyer, Regis, ...... 568A Mason, James, ...... 860B Mhatre, Siddhita, ...... 433A* Mason, James M., ...... 354C*, 387C Michel, Marcus, ...... 148 Matakatsu, Hitoshi, ...... 239B* Michelson, Alan M., ...... 100, 835A Mateos-Langerak, Julio, ...... 133 Michelson, A. M., ...... 109 Matson, Emily, ...... 460A Michelson, Sarah, ...... 433A Matsumoto, Ken, ...... 650B Michiewicz, Monique, ...... 727A Matsumoto, Kenjiroo, ...... 223A Mikaelyan, Arsen, ...... 754A Matsumoto, Kozo, ...... 601A Mikitova, Veronika, ...... 614B* Matsuno, Kenji, ...... 57, 156, 168C, 223A, 550A, 733A, 949A Miller, Sean, ...... 435C Matthews, Kathy A., ...... 457A Miller, Steven, ...... 828C* Mattiuzzo, Nicolas, ...... 504C, 926B Milon, Beatrice, ...... 386B* Mattiuzzo, Nicolas R., ...... 480C, 839B Milton, Claire C., ...... 4 Mattox, William, ...... 877A Milyaev, Nestor, ...... 135 Matunis, Erika, ...... 142 Min, Sarah, ...... 722B Matunis, Erika L., ...... 906C Minakhina, Svetlana, ...... 907A Matzat, Leah H., ...... 862A* Miner, David, ...... 821B Matzkin, Luciano M., ...... 472A, 522C Mino, Rosa, ...... 700A Mavong, Setong, ...... 735C Minoda, Aki, ...... 76, 363C*, 366C, 381C May, G., ... 836B Mintseris, Julian, ...... 136, 946A Mayau, Véronique, ...... 86 Mirela, Belu, ...... 475A Maynard, Kristina,...... 484A Mirouse, Vincent, ...... 169A* McCall, Kim, ...... 279C, 294C Mirth, Christen, ...... 314B McCartney, Brooke, ...... 254B, 255C Mirth, Christen K., ...... 328A, 505A* McClatchey, Andrea, ...... 110 Mishra, Arati, ...... 400A McClure, Kimberly, ...... 398B Mistry, Hemlata, ...... 762C McCutchan, Michael, ...... 915C Mitchell, Naomi,...... 303C, 796A McDonald, Jocelyn, ...... 218B Mitrofanov, Vladimir G., ...... 523A McGregor, Alistair P., ...... 31 Miyamoto, Tetsuya, ...... 687C*, 690C McGurk, Leeanne, ...... 430A Miyawaki, Atsushi, ...... 637A McInally, Shane, ...... 73 Mizutani, Claudia M., ...... 475A* McIntyre, Lauren M., ...... 487A, 811A Mlodzik, Marek, ...... 158B, 163A McKean, Kurt, ...... 631A Moberg, Kenneth H., ...... 8 McKee, Bruce, ...... 320B, 370A modENCODE Drosophila Transcriptome Project, ...... 855C McLeod, Catherine, ...... 128 ModEncode Fly Transcriptome Group, ...... 851B McManus, C. Joel,...... Plenary Session I (continued), 483C Modestova, Elena, ...... 754A McNeil, Casey L., ...... 535A*, 536B* Mohan, Ryan D., ...... 376A* McNeil, Gerard, ...... 957C Mohd Azzam, Mohd Ghows, ...... 575B* McNeil, Gerard P., ...... 574A* Mohler, Jym, ...... 509B* McVey, Mitch, ...... 43, 265A Mohr, Stephanie, ...... 452B Mears, Kyle, ...... 605B Mohr, Stephanie E., ...... 133* Mechler, Bernard, ...... 252C Moiser, Aaron, ...... 631A Meduri, Ramakrishna, ...... 697A Mokalled, Mayssa H., ...... 559A Medvedeva, Anna,...... 662B Moline, Christopher, ...... 181A Megraw, Timothy L., ...... 309C Molla, Linda, ...... 869B* Mehrotra, Sonam, ...... 292A Mollereau, Bertrand, ...... 288C Mei, Amanda, ...... 373A Monahan, Amanda J., ...... 213C* Meiklejohn, Colin,...... 27, 451A Monfort-Prieto, Elena, ...... 867C, 870C* Meiklejohn, Colin D., ...... 542B* Monribot, Juan, ...... 391A* Meinertzhagen, Ian A., ...... 787A Monroe, Kate, ...... 189C Meisel, Richard, ...... 34* Montell, Craig, ...... 684C Melicharek, David J., ...... 20 Montell, Denise, ...... 91 Melkani, Anju, ...... 172A, 461B Montell, Denise J., ...... 13 Melkani, Girish C., ...... 50*, 172A, 461B Montminy, Marc, ...... 129 Meller, Victoria, ...... 916A Montooth, Kristi, ...... 27 Mellone, Barbara, ...... 375C* Montooth, Kristi L., ...... 38, 451A, 793A Melzer, Juliane, ...... 721A* Moon, Nam-Sung, ...... 110 97

Speaker and Author Index

Moon, Sungjin, ...... 603C* Neisch, Amanda, ...... 338B Moore, Jacqueline, ...... 476B* Neisch, Amanda L., ...... 249C* Morais da Silva, Sara, ...... 261C* Nelson, Jonathan O., ...... 865A* Morales-Rosado, Joel A., ...... 377B Nelson, Kevin S., ...... 89* Moran, Victoria, ...... 916A Neubueser, Dagmar D. A., ...... 176B Morata, Gines, ...... 283A Neumuller, Ralph, ...... 133 Moreno, J. C., ...... 845B Newbold, Samuel P., ...... 105 Morgan, Rachel, ...... 556A Newfeld, Stuart, ...... 748A Morin, Ismael, ...... 615C Newfeld, Stuart J., ...... 54*, 341B* Morley, Samantha, ...... 130 Nfonsam, Landry E., ...... 927C* Morocco, Perry, ...... 392B* Nguyen, Jen K., ...... 410B* Morrell, John, ...... 758B Nguyen, Jeremy, ...... 279C Morris, Ginny, ...... 407B Nguyen, Kerrie K., ...... 912C Morris, Jason, ...... 335B Nguyen, Son C., ...... 393C* Morrison, Carolyn A., ...... 765C Nguyen, Tram, ...... 576C Morriss, Ginny, ...... 747C* Ni, Jian-Quan, ...... 952A Mortier, Magda, ...... 635B Ni, Jianquan, ...... 951C Mortin, Mark, ...... 286A Ni, Lina, ...... Plenary Session I Morton de Lachapelle, Aitana, ...... 59 Ni, Xiaochun, ...... 116* Moshfegh, Cameron, ...... 808A Nichols, Charles D., ...... 72* Moshkovich, Nellie, ...... 862A Nicolay, Brandon, ...... 339C Mossman, Jim, ...... 537C* Nie, Minghua, ...... 749B Motsinger-Reif, Alison, ...... 37 Nie, Zuquin, ...... 796A Mottier-Pavie, Violaine, ...... 309C Nien, Chung-Yi, ...... 799A, 801C* Moya, Noel, ...... 129 Niepielko, Matthew G., ...... 56* Mu, Frank, ...... 324C Niessen, Sherry, ...... 129 Mudge, Joann, ...... 927C Nikitina, Ekatherina, ...... 662B* Mugat, Bruno, ...... 237C Nilson, Kyle A., ...... 78 Mukherjee, Konark, ...... 679A Nilson, Laura, ...... 179B Mukherjee, Kusumika, ...... 919A* Nishimura, Mayuko, ...... 790A* Mukherjee, Subhas, ...... 413B Niwa, Ryusuke,...... 472A Mulcahy, Heidi, ...... 121* Nnah, Israel, ...... 700A Murali, Archana, ...... 891C Noçka, Arsida, ...... 179B* Murat, Sophie, ...... 472A Noguchi, Tatsuhiko, ...... 606C Murray, Michael J., ...... 783C Nolte, Viola, ...... 521B, 929B Murray, Sheryl M., ...... 101* Nomie, Krystle J., ...... 642C* Musashe, Derek, ...... 434B* Nonaka, Shigenori, ...... 57 Mutti, Alexa, ...... 735C Nongthomba, Upendra, ...... 562A, 807C Myllymäki, Henna, ...... 150* Nordman, Jared T., ...... 63* Novakova, Milena, ...... 450C Novelo, Luis L., ...... 487A N Novo, Michael, ...... 936C Nowak, Katarzyna, ...... 342C* Nowosielska, Anetta, ...... 11 Näär, Anders, ...... 352A Nowotarski, Stephanie, ...... 180C* Nachun, Dan, ...... 449B Nudell, Yoav, ...... 791B* Nag, Sanjay, ...... 786C* Nurminsky, Dmitry, ...... 386B Nagao, Aya, ...... 5 Nuzhdin, Sergey, ...... 511A, 643A, 930C Nagengast, Alexis, ...... 957C Nuzhdin, Sergey V., ...... 487A, 494B, 811A Nagengast, Alexis A., ...... 762C*, 876C* Nye, Jessica, ...... 538A* Nagpal, Radhika, ...... 1 Nystul, Todd, ...... 893B Najjar, Kristina, ...... 399C Nystul, Todd G., ...... 145* Nakagoshi, Hideki, ...... 741C Nakamura, Mai, ...... 5 Nakamura, Mitsutoshi, ...... 57, 168C, 550A, 733A* O Nakazawa, Naotaka, ...... 57, 168C, 550A, 733A, 949A* Nally, Emma, ...... 806B Nam, Sang-Chul, ...... 739A, 740B Oak, Si Won, ...... 958A Namdar, Yuval, ...... 291C Obar, Robert, ...... 136, 946A Nandanan, Kavya, ...... 317B Obbard, Darren J., ...... 627C* Na-Ra, Shin, ...... 395B Oberlick, Elaine, ...... 393C Nataraja, Niranjana, ...... 817A Obniski, Rebecca, ...... 142 Nauman, Grace A., ...... 912C Ocana, Michelle, ...... 133 Navarro, Caryn, ...... 573C, 576C O'Connell, Mary, ...... 430A N. dos Santos, Ramon, ...... 654C O'Connor, Michael, ...... 730A Necakov, Aleksandar S., ...... 195C* Ocorr, Karen, ...... 12, 49*, 50, 402C, 403A, 412A, 790A, 791B Neckameyer, Wendi S., ...... 657C, 665B, 714C* Odenwald, Ward F., ...... 719B, 832A, 910A Neff, D., ...... 658A* Oderberg, Isaac, ...... 375C Nègre, Nicholas, ...... 828C O'Donnell, Janis, ...... 425B Negre, Nicolas, ...... 765C Ogihara, Mitsunori, ...... 938B, 940A Neher, Hayley, ...... 605B Ohler, Uwe, ...... 815B 98

Speaker and Author Index

Ohno, Katsuhito, ...... 378C Parker, Nathan, ...... 337A Ohsawa, Shizue, ...... 5* Parkhurst, Susan, ...... 187A Oikemus, Sarah R., ...... 43* Parkhurst, Susan M., ...... 221B Ojwang, Audrey, ...... 137 Parks, Annette L., ...... 457A* Okabe, Masataka, ...... 601A Parmentier, Marie-Laure, ...... 237C Okado, Kiyoshi, ...... 628A* Paro, Simona, ...... 430A Okajima, Tetsuya, ...... 156, 223A Parra-Peralbo, Esmeralda, ...... 771C Okumura, Takashi, ...... 168C, 733A, 949A Parrott, Benjamin B., ...... 881B* Oldham, Sean, ...... 131, 412A Parsons, Brendon, ...... 234C Olenina, Ludmila V., ...... 858C Parsons, Brendon D., ...... 561C* Olenkina, Oxana M., ...... 858C Partridge, Linda, ...... Plenary Session I Olguín, Patricio, ...... 300C Pastor-Pareja, Jose C., ...... 102* Oliveira, Marisa M., ...... 328A* Patricia, Ramos-Morales, ...... 447C Oliver, Brian, ...... 34, 480C, 504C, 590B, 839B, 926B Paulucci, Ezequiel, ...... 856A Olson, Eric N., ...... 559A, 560B Payankaulam, Sandhya,...... 842B Önel, Susanne-Filiz, ...... 202A Payrastre, Bernard, ...... 321C Önfelt Tingvall, Tove, ...... 636C Payre, François, ...... 31, 321C Oortveld, Merel A. W., ...... 41 Payre, Francois, ...... 90*, 829A* Orgogozo, Virginie, ...... 472A Peabody, Nathan, ...... 659B* Orozco, Pablo, ...... 521B Pearce, Stephen, ...... 922A Orozco-ter Wengel, Pablo, ...... 929B Pearl, Sivanne, ...... 106 Orr-Weaver, Terry L., ...... 63, 319A Pearman, Krista, ...... 783C Orsak, Thomas, ...... 769A Pechenick, Dov A., ...... 912C Orsi, Guillermo, ...... 385A Pei, Shanshan, ...... 211A Ostrovsky, Lilly, ...... 679A Peifer, Mark, ...... 155, 162C, 180C, 324C Osumi-Sutherland, David J., ...... 135* Peixoto, Alexandre A., ...... 652A Ote, Manabu, ...... 650B Pellikka, Milena,...... 233B, 458B*, 547A Othmer, Hans, ...... 730A Peng, Cheng, ...... 780C O'Tousa, Joseph E., ...... 236B Peng, Felix, ...... 256A Ott, Kristen Mary, ...... 576C* Peng, Hanchuan, ...... 677B* Ou, Qiuxiang, ...... 764B, 806B Peng, Xinyun, ...... 137 Owald, David, ...... 691A Peng, Ying, ...... 170B* Oyallon, Justine, ...... 615C* Pennetier, Delphine, ...... 615C Ozaki, Ayumi, ...... 57, 733A Pennington, Whitney, ...... 686B Ozdemir, Anil, ...... 846C Perdigoto, Carolina, ...... 896B Ozdowski, Emily F., ...... 729C* Pereira, Paulo S., ...... 301A Öztürk, Arzu, ...... 743B Pereira, Sara, ...... 311B Perez Palencia, Raquel, ...... 148 Perez San Juan, Beatriz, ...... 269B* P Perkins, Lizabeth, ...... 951C Perkins, Lizabeth A., ...... 952A Perkowski, John,...... 791B Paddock, Brie, ...... 435C* Peronnet, Fredrerique, ...... 888C Paden, Katie Ann,...... 912C Perrimon, N., ...... 422B Paetkau, Don, ...... 957C Perrimon, Norbert, ...... 1, 133, 185B, 260B, 336C, Page-McCaw, Andrea, ...... 634A ...... 452B, 951C, 952A Paik, Wonbeom, ...... 315C Perry, Dustin W., ...... 214A* Pail, Litty, ...... 760A Perry, Michael, ...... 138, 810C, 830B* Palomera, Zoraya, ...... 391A Peters, Kim, ...... 85 Palozola, Katherine C., ...... 693C Peters, Nathaniel, ...... 577A* Pan, Hongling, ...... 140 Petersen, Camille, ...... 265A Pan, Yufeng, ...... 70* Peterson, Jeanne, ...... 279C Panaram, Kanchana, ...... 640A, 641B Pézeron, Guillaume, ...... 584B* Pancratov, Raluca, ...... 256A* Pfleger, Cathie, ...... 432C Pandey, Ravikant, ...... 400A Pfleger, Cathie M., ...... 48 Panicker, Leelama, ...... 401B Phadnis, Nitin, ...... 492C* Panikar, Chitra, ...... 383B Phanstiel IV, Otto, ...... 419B Panok, Lena, ...... 756C Philip, Benjamin N., ...... 517A Panzano, Vincent, ...... Plenary Session I Philip, Philge, ...... 397A Papoulas, Ophelia, ...... 61*, 905B Phillips, Angela, ...... 775A Parikh, Roshni, ...... 795C, 875B Piazza, Nicole, ...... 130 Parikka, Mataleena, ...... 616A Pick, Leslie, ...... 470B, 750C Paris, Mathilde, ...... 840C* Piergentili, Roberto, ...... 350B Park, Jae, ...... 715A Pimenta-Marques, Ana, ...... 323B Park, Kwanho, ...... 713B Pines, Mary, ...... 175A Park, Maiyon, ...... 197B Pirrotta, Vincenzo, ...... 81, 366C, 378C, 381C Park, Peter J., ...... 381C Pitsouli, Chrysoula, ...... 336C* Park, Seung Hwan, ...... 345C Plaçais, Pierre-Yves, ...... 69 Park, Soo, ...... 946A Plaza, Serge, ...... 90, 829A Park, Sung-Yeon, ...... 275B* Pletcher, Scott, ...... 625A, 784A Parkash, Ravi, ...... 525C, 792C Pletcher, Scott D., ...... 773B 99

Speaker and Author Index

Plotkin, Jesse, ...... 837C Ramel, Damien, ...... 220A* Podlaha, Ondrej, ...... 478A Rämet, Mika, ...... 150, 616A Podufall, Jasmin, ...... 705C Ramirez, Laura C., ...... 20 Poernbacher, Ingrid, ...... 144* Rana, Nadia A.,...... 154 Pogson, Joe, ...... 436A* Rand, David, ...... 537C, 763A Pohl, Jascha, ...... 399C Rand, David M., ...... 27*, 451A Poisot, Emilie, ...... 888C Ranganathan, Nanditha, ...... 306C Polen, Michael, ...... 762C Ranjan, Ganguly, ...... 822C Polesello, Cédric, ...... 900C Ranum, Ruth, ...... 279C Polihronakis Richmond, Maxi,...... 518B* Raska, Ivan, ...... 252C Polston, Eva, ...... 781A Ratcliffe, Melissa, ...... 190A Polyzos, Aris, ...... 76 Rathke, Christina, ...... 602B Pontier, Stephanie M., ...... 240C* Ratnappan, Ramesh, ...... 29 Ponting, Chris, ...... 854B Ravid, Liat, ...... 289A* Pool, John E., ...... 519C* Ravisankar, Padmapriyadarshini, ...... 477C* Poon, Carole L. C., ...... 4 Rawson, Joel, ...... 74*, 758B Posakony, James, ...... 507C, 825C, 828C Ray, Anandasankar, ...... 73, 689B Posukh, Olga, ...... 364A* Read, Renee D., ...... 44* Pouille, Philippe-Alexandre, ...... 6 Reardon, Kathryn, ...... 412A Poulton, John, ...... 324C* Rebay, Ilaria, ...... 848B Powell, Zachary B., ...... 958A Rebelo, Sofia Raquel, ...... 334A Pradhan, Sarala J., ...... 16* Rebollo, Elena, ...... 736A Prakash, Ravi, ...... 930C Reddy, Hemakumar M., ...... 387C* Prantera, Giorgio, ...... 607A Reed, Laura K., ...... 37* Prat-Rojo, Carla, ...... 6, 736A* Reeve, Simon R., ...... 135 Preat, Thomas, ...... 69 Reeves, Gregory T., ...... 53* Presgraves, Daven C., ...... 542B Reich, John C., ...... 905B* Pret, Anne-Marie, ...... 293B Reif, David, ...... 37 Prevost, Nicolas, ...... 770B Reimels, Theresa, ...... 48* Price, Jason P., ...... 343A Reinitz, John, ...... 756C Price, Nathan D., ...... 920B Reiss, Kristina, ...... 181A* Primus, Shekerah, ...... 591C* Reiter, Lawrence, ...... 405C Pritchett, Tracy, ...... 294C Reiter, Lawrence T., ...... 404B Prochiantz, Alain, ...... 237C Remillard, Ciara A., ...... 437B* Pronovost, Stephen M., ...... 177C Ren, Fangfang, ...... 886A* Prososki, Andrew, ...... 934A* Renkawitz-Pohl, Renate, ...... 173B, 182B, 202A, 203B, 602B Prudencio, Pedro, ...... 323B Resendez, D., ...... 845B Przytycka, Teresa, ...... 839B Reubens, Michael, ...... 365B* Ptácek, Louis, ...... 758B Reynolds, Elaine R., ...... 459C* Puli, Oorvashi Roy G., ...... 741C* Rhee, David, ...... 136 Pulido, Dianne, ...... 668B Ribeiro, Ines, ...... 196A* Pulver, Stefan, ...... Plenary Session I Ribeiro, Inês, ...... 410B Pyfrom, Sarah Catherine, ...... 604A* Rice, Gavin, ...... 831C* Pyrowolakis, Georgios, ...... 59 Richards, Stephen, ...... 25*, 928A Pyrowolakis, Giorgos, ...... 107, 818B Richards, Steven M., ...... 438C* Pyrtel, Khateriaa, ...... 315C Richter, Daniel, ...... 326B Rico, Amber, ...... 777C* Riddiford, Lynn, ...... 505A, 646A Q Riddle, Nicole C., ...... 366C*, 381C, 392B Rideout, Elizabeth J., ...... 132*, 302B, 778A* Ridyard, Marc, ...... 708C Qi, Hongying, ...... 9*, 94 Riechmann, Veit, ...... 897C Qian, Yue, ...... 882C* Riesgo Escovar, Juan R., ...... 524B Quijano, Janine, ...... 341B Riesgo Escovar, Juan Rafael, ...... 555C Quinn, Leonie, ...... 796A Riesgo-Escovar, Juan Rafael, ...... 241A Quinn, Leonie M., ...... 303C* Rimesso, Gerard, ...... 238A Qutub, Kristen, ...... 442A Rincon-Limas, Diego, ...... 426C, 429C, 439A, 937A Rinner, Oliver, ...... 242B R Ríos-Barrera, Luis Daniel, ...... 241A* Rishko, Valentyna, ...... 454A Rivera Pomar, Rolando, ...... 856A Raabe, Isabel, ...... 148 Rizzo, Nicholas P., ...... 201C Raabe, Thomas, ...... 721A Robbins, Renée M., ...... 547A* Raad, Hussein, ...... 770B Roberts, Dave, ...... 324C Radolf, Martin, ...... 565A Roberts, David, ...... 155 Raffa, Grazia D., ...... 351C Roberts, Logan,...... 437B, 668B Rahman, Mokhlasur, ...... 52* Robichon, Alain, ...... 770B Rai, Mamta, ...... 562A* Robin, Marion, ...... 288C Raikhel, Alexander, ...... 852C* Robinett, Carmen, ...... 70 Ramaswami, Mani, ...... 16 Robinson, Brooks G., ...... 399C* Ramaswamy, Sridhar,...... 110 Robinson, Gene E., ...... 920B 100

Speaker and Author Index

Rochlin, Kate M., ...... 563B* Sanchez, Victoria M., ...... 208A* Rodriguez, Janel, ...... 346A* Sanchez-Garcia, Jonatan, ...... 429C, 439A* Rodriguez, Jessica, ...... 412A Sánchez-Herrero, Ernesto, ...... 745A Rodriguez-Mesa, Evelyn, ...... 221B* Sandmann, Thomas, ...... 950B Rodriguez-Zas, Sandra, ...... 920B Sandoval, Hector, ...... 224B, 420C, 446B Roeder, Thomas, ...... 453C, 639C Sang, Tzu-Kang, ...... 440B*, 794B Roegiers, Fabrice, ...... 226A Sang-Wang, Lee, ...... 395B Rogers, Stephen L., ...... 85 Sansone, Christine L., ...... 585C* Rohn, Jennifer, ...... 185B Santiago, Ivan J., ...... 700A Rokia-Mille, Selim Ben, ...... 770B Santolini, Marc, ...... 829A Rollins, Janet, ...... 250A Santos, Raquel, ...... 97 Rong, Yikang S., ...... 355A* Santos, Raquel A. M., ...... 262A* Rosa, André, ...... 572B Sanyal, Abhijit, ...... 841A* Rosa, Andre, ...... 323B Sanz-Parra, Arantza, ...... 614B Rosas, Alexandre, ...... 654C Sanz Parra, Arantza, ...... 621C Rosbash, Michael, ...... Opening General Session, 71 Sapiro, Anne, ...... 280A, 282C* Rose, Michael R., ...... 510C Sarpal, Ritu, ...... 233B Ross, Benjamin, ...... 367A* Sarraf-Zadeh, Ladan, ...... 663C* Ross, Jermaine, ...... 719B, 832A*, 910A Sartori, Sienna M., ...... 556A* Rossi, Fabrizio, ...... 724A Sasamura, Takeshi, ...... 223A Roth, Bryan L., ...... 72 Sato, Brian, ...... 14 Rothchild, David B., ...... 958A Sato, Yoshitaka, ...... 5 Rottig, Carmen, ...... 325A Satyaki, Rajavasireddy P., ...... 368B* Rouault, Herve, ...... 829A Saunders, Aleister, ...... 435C Roubinet, Chantal, ...... 312C, 321C Saville, Ken, ...... 957C Roure, Virginie, ...... 390C Savitsky, Mikhail,...... 380B*, 381C, 918C Royou, Anne, ...... 322A Savvateeva-Popova, Elena, ...... 662B Rozeboom, Leslie M., ...... 16 Schaaf, Allison, ...... 80* Rual, Jean-François, ...... 136, 946A Schaeffer, Stephen, ...... 497B Rubin, Thomas, ...... 888C Schatz, Bruce R., ...... 920B Rubinstein, Boris Y., ...... 1 Schedl, Paul, ...... 593B Rubinstein, C. Dustin, ...... 653B* Schenck, Annette, ...... 41 Ruderman, Brandon, ...... 958A Scherer, Steven, ...... 928A* Rudolf, Anja, ...... 182B* Schiabor, Kelly M., ...... 688A* Rudolph, Timothy, ...... 762C, 876C Schilkey, Faye, ...... 927C Ruiz, Oscar E., ...... 548B* Schinaman, Joseph, ...... 654C, 655A Rulifson, Eric, ...... 17 Schittenhelm, Ralf B., ...... 242B* Rundell, Ann, ...... 113 Schleiffer, Alexander, ...... 118 Ruohola-Baker, Hannele, ...... 271A Schlenke, Todd A., ...... 624C Rus, Florentina, ...... 632B Schloetterer, Christian W., ...... 521B*, 929B* Rushlow, Chris, ...... 799A, 801C Schmidt, Imke, ...... 702C* Russo Heinrichsen, Erilynn, ...... 415A* Schmidt, Kelsey,...... 349A Rutter, Jared, ...... 769A Schneider, David, ...... 123, 618C, 633C Ryan, Kathryn M., ...... 827B Schnorrer, Frank, ...... 565A Ryazansky, Sergei S., ...... 858C Schöck, Frieder, ...... 409A, 455B, 599B Rynearson, Shawn, ...... 864C Schoeck, Frieder, ...... 185B Ryoo, Hyung Don, ...... 66 Schoeck, Frieder B., ...... 183C* Schoenfelder, Kevin E., ...... 145 Schönbauer, Cornelia, ...... 565A* S Schrider, Daniel R., ...... 26* Schuettengruber, Bernd, ...... 390C Schulman, Victoria K., ...... 564C* Sabo, Peter, ...... 838A Schulte, Michelle A., ...... 629B* Sackton, Timothy B., ...... 493A* Schulz, Cordula, ...... 881B, 882C Saggio, Isabella, ...... 351C Schulz, Robert A., ...... 567C, 892A Saharia, Gaurav, ...... 335B Schulze, Karen, ...... 140, 226A Saif, Taher, ...... 728B Schulze, Sandra R., ...... 460A*, 605B* Sajjadi, Shirine, ...... 912C Schumacher, Joel O., ...... 522C* Salinas-Hernandez, Jannet E., ...... 845B* Schupbach, Trudi,...... 87 Salit, Marc, ...... 926B Schwartz, Yuri B., ...... 81*, 366C, 381C* Sallé, Jérémy, ...... 270C* Schwarz, Thomas L., ...... 88 Saltz, Julia B., ...... 643A* Schweisguth, François, ...... 86, 240C, 896B Salz, Helen,...... 874A Schwimmer, David B., ...... 481A Salz, Helen K., ...... 879C Scoggin, Shane, ...... 134 Salzmann, Viktoria, ...... 883A* Scott, Kristin, ...... 920B Samarajeewa, Hasitha, ...... 938B, 940A, 945C Scott, Maxwell J., ...... 494B Samba, Sindhu, ...... 517A Scroggs, Reese, ...... 405C Saminadin-Peter, Sarah S., ...... 520A* Sealfon, Rachel, ...... 828C Samsonova, Anastasia, ...... 133 Seat, Angela, ...... 316A Samsonova, Maria, ...... 756C Segura, Adrian, ...... 315C Sanchez, Heriberto, ...... 782B Seher, Thaddeus, ...... 478A* 101

Speaker and Author Index

Seigneur, Erica M., ...... 401B* Simonds, William, ...... 401B Seisenbacher, Gerhard, ...... 342C Simonette, Rebecca A., ...... 645C Séjourné, Julien, ...... 69* Simonova, Olga, ...... 754A* Sen, Aditya, ...... 143 Simonsen, Anne, ...... 782B Sen, Anindya, ...... 225C, 228C Sims, David, ...... 185B* Sengupta, Sonali, ...... 330C Sinden, Daniel, ...... 142 Sentmanat, Monica, ...... 371B Singh, Amit, ...... 306C, 734B, 741C Seo, Yoon Seok, ...... 414C Singh, Mona, ...... 89 Serrano, Yazmin L., ...... 678C* Singh, Nadia, ...... 28* Serway, Christine N., ...... 669C* Singh, Shree R., ...... 901A* Serysheva, Ekatherina, ...... 163A Singh, Sukhdeep, ...... 20 Sethi, Maya, ...... 230B Singhania, A., ...... 109 Sever, Aubrey, ...... 776B, 782B Sinha, Pradip, ...... 400A Severson, David W., ...... 495C Sinha, Saurabh, ...... 139, 469A Sexton, Travis, ...... 579C Sinsimer, Kristina S., ...... 15*, 868A Sexton, Travis R., ...... 214A Sirohi, Neha, ...... 762C Seyedoleslami Esfahani, Shiva, ...... 636C* Sitaram, Poojitha, ...... 93* Sha, Kai, ...... 715A* Sitnik, Jessica,...... 586A* Shaffer, Christopher, ...... 957C* Sivachenko, Anna, ...... 71* Shaffner, Caroline, ...... 595A Siwanowicz, Igor, ...... 69 Shahi, Varun, ...... 668B Skaer, Helen, ...... 587B Shahrestani, Parvin, ...... 510C Skelly, Stephanie, ...... 606C* Shakhmantsir, Iryna, ...... 853A* Slabbaert, Jan, ...... 925A Shalovylo, Yulia, ...... 406A Slaughter, Brian, ...... 316A Shanower, Gregory, ...... 381C Slawson, Justin, ...... 679A* Sharifai, Nima, ...... 938B, 944B* Slezinger, Mikhail, ...... 754A Sharma, Arun, ...... 958A Slone, Jesse, ...... 690C* Shaw, P. C., ...... 422B Slusarski, Diane, ...... 51 Shaw, Rachael L., ...... 900C* Small, Stephen, ...... 55, 476B Shcherbata, Halyna, ...... 146, 454A Small, Steve, ...... 834C Shcherbata, Halyna R., ...... 42 Smallwood, Tangi, ...... 248B Sheahan, Tayler Diane, ...... 578B* Smibert, Craig, ...... 861C Shelton, Lauren G., ...... 376A Smith, Aaron, ...... 331A Shelton IV, Claude, ...... 83* Smith, Brittany N., ...... 935B* Shen, Weiping, ...... 188B Smith, Christopher D., ...... 857B Sheng, Xuteng, ...... 142 Smith, Dean P., ...... 24 Shepherd, Brian, ...... 449B Smith, Leah, ...... 597C, 604A Sher, Noa, ...... 63 Smith, Robin, ...... 938B, 940A Sherrard, Kristin, ...... 184A* Sokol, Nicholas S., ...... 850A Sherwood, Nina T., ...... 729C Sokolova, Olesia A., ...... 858C Shi, Alvin H., ...... 958A Sokolowski, Marla B., ...... 41 Shim, Hye-Seok, ...... 952A Solinet, Sara, ...... 312C Shingleton, Alexander, ...... 337A* Somers, Gregory, ...... 724A Shinzawa, Naoaki, ...... 628A Song, Kyung Han, ...... 633C* Shlevkov, Evgeny, ...... 283A* Song, Xiangyu, ...... 687C, 690C Shogren-Knaak, Michael A., ...... 343A Song, XIangzhi, ...... 672C Shokri, L., ...... 109 Soo-Jong, Um, ...... 395B Short, Sarah M., ...... 122* Sorace, Brian J., ...... 442A* Shteyn, Vladimir, ...... 375C Sorokina, Svetlana Y., ...... 523A* Shultz, Jeff, ...... 470B Soshnev, Alexey A., ...... 78* Shuqing, Ji, ...... 368B Sotillos, Sol, ...... 165C Shvartsman, Stanislav, ...... 914B Souaiaia, Tade, ...... 511A Shvartsman, Stanislav Y., ...... 107, 208A, 246C, 809B, 933C Soukup, Sandra, ...... 614B Sibley, Christopher D., ...... 121 Sousa-Neves, Rui, ...... 655A* Sidhu, Sachdev, ...... 861C Sousa-Neves, Rui S., ...... 654C* Sieber, Matt, ...... 126* Sousa-Nunes, Rita, ...... 724A Siechen, Scott, ...... 728B Spana, Eric P.,...... 958A* Signor, Sarah A., ...... 479B* Sparks, Nicole R., ...... 443B* Sigrist, Stephan, ...... 691A, 705C Spirov, Alexander V., ...... 752B, 755B* Siller, Saul S., ...... 411C* Spletter, Maria, ...... 681C Silva, Patricia, ...... 97, 262A Spokony, Rebecca F., ...... 765C* Silvennoinen, Olli, ...... 150 Sporn, Peter H. S., ...... 40 Silverman, Neal, ...... 632B* Spracklen, Andrew, ...... 98 Sim, Choon Kiat, ...... 689B* Spradling, Allan, ...... 92, 140 Simcox, Amanda, ...... 154, 244A Spradling, Allan C., ...... 145 Simcox, Amanda A., ...... 760A* Spratford, Carrie M., ...... 742A* Simich, Michael, ...... 821B Springer, Chelsea, ...... 137, 696C Simmelink, Andrew L., ...... 441C* Srivastava, Sudeep, ...... 32 Simmons, Amanda, ...... 142 Staller, Max V.,...... 833B* Simon, Dawn, ...... 508A Stamatoyannopoulos, John, ...... 838A Simon, Rocio, ...... 394A* Stamm, Joyce, ...... 957C 102

Speaker and Author Index

Stapleton, Mark, ...... 136 Swarup, Sharan, ...... 152* Starz-Gaiano, Michelle, ...... 213C, 219C, 612C Swenson, Joel, ...... 357C, 369C* Starz-Gaiano, Michelle A.,...... 891C* Szabad, Janos, ...... 273C Stathopoulos, Angelike, ...... 53, 846C* Sze, Sing-Hoi, ...... 494B Stec, Wojciech, ...... 212B Sznajder, Jacob I.,...... 40 Steele, Latishya J., ...... 243C Stefaniuk, Catherine, ...... 816C Steinberg, Barrett, ...... 640A T Stempniewicz, Peter, ...... 812B Stenberg, Per, ...... 81, 397A* Taillebourg, Emmanuel, ...... 153*, 635B Stern, David, ...... 529A Taipan, Jemma, ...... 279C Stern, David L., ...... 31 Takaesu, Norma, ...... 54 Stevens, Traci L., ...... 181A Takeo, Satomi, ...... 317B* Stevenson, Kraig, ...... Plenary Session I (continued) Tamori, Yoichiro, ...... 299B* Stevenson, Kraig R., ...... 483C Tan, Julie, 250A Steward, Ruth, ...... 907A Tan, Kai, ...... 78 Stewart, Andrea, ...... 22*, 958A Tan, William, ...... 907A* Stewart, Mara, ...... 418A Tan, Ying, 296B*, 717C Stewart, Mara N., ...... 39* Tan, Yiyong, ...... 936C Stewart, Shannon, ...... 685A Tanaka, Tsubasa, ...... 637A Stickel, Stefanie, ...... 418A* Tanaka-Matakatsu, Miho, ...... 802A* Stinchfield, Michael, ...... 54, 341B Tanentzapf, Guy, ...... 175A Stine, Rachel R., ...... 906C* Tang, Ho Lam, ...... 91 St. Johnston, Daniel, ...... 169A Tang, Jing, 716B Stocker, Hugo, ...... 144, 242B, 325A, 342C, 663C Tang, Jonathan, ...... 708C Stokes, Chris, ...... 672C Tang, Lingfeng, ...... 215B* Stokes, Christopher, ...... 674B Tang, Wei, 296B Stoller-Conrad, Jessica, ...... 567C Tang, Xiaofang, ...... 720C Stoller-Conrad, Jessica Renee, ...... 892A* Tang Sherwood, Nina, ...... 22 Stolyarenko, Anastasia D., ...... 858C Taniguchi, Kiichiro, ...... 168C, 550A, 733A, 949A Stone, Bryan, ...... 417C Tanimoto, Hiromu, ...... 69 Stone, Eric, ...... 25, 28 Tanner, Elizabeth,...... 279C Stone, Hunter, ...... 597C Tansey, Terese, ...... 100 Stoner, Camilla, ...... 508A Tao, Hirotaka, ...... 51 Stowers, Levi, ...... 51 Tao, Yun, . 540C* St. Pierre, Susan, ...... 296B Tapon, Nicolas, ...... 900C Strutt, David, ...... 157A Tare, Meghana, ...... 734B* Strutt, David I., ...... 99 Tarone, Aaron, ...... 777C, 779B Stultz, Brian, ...... 275B Tarone, Aaron M., ...... 494B* Stunnenberg, Hendrik G.,...... 41 Tatar, Marc, ...... 526A, 632B, 766A Sturgill, David, ...... 926B Tauber, John, ...... 462C* Sturgill, David M.,...... 480C Tavaré, Simon, ...... 930C Su, Ming-Tsan, ...... 427A Tawny, Cuykendall, ...... 368B Su, Shihuang, ...... 877A Taylor, Amy, ...... 46, 212B Su, Tin Tin, ...... 39, 278B, 284B*, 418A Tchénio, Paul, ...... 69 Suarez, Katia, ...... 776B, 782B Tedjakumala, Stevanus R., ...... 69 Subramaniam, Shankar, ...... 507C Téllez-García, Aldo A., ...... 524B* Suchy, Sarah, ...... 765C Ten Hagen, Kelly G., ...... 588C Suggs, Jennifer A., ...... 461B* Tennessen, Jason M., ...... 767B Suissa, Yaron, ...... 593B Tepass, Ulrich, ...... 171C, 233B, 458B, 547A Sujkowski, Alyson, ...... 130 Terman, Jonathan R., ...... 210C Sukhanova, Madina Z., ...... 243C* ter Stal, David, ...... 171C* Sullivan, Mackenzie, ...... 306C Terzioglu Kara, Ece, ...... 743B* Sullivan, William, ...... 2, 322A Terzo, Esteban, ...... 272B* Sulovari, Arvis, ...... 912C Tesseroli, Danielle, ...... 466A Sun, Bo, ...... 958A Teves, Sheila, ...... 356B* Sun, Jianjun, ...... 92* Thackeray, Justin R., ...... 329B* Sun, Jie, ...... 728B Tharadra, Sana, ...... 73 Sun, Lin, .. 543C*, ...... 841A Theobald, Douglas, ...... Plenary Session I Sun, Y. Henry, ...... 701B Théodore, Laurent, ...... 888C Sun, Yi, .... 87* Theopold, Ulrich, ...... 630C* Sung, Hung-wei, ...... 62* Therrien, Marc, ...... 232A Sunkel, Claudio, ...... 261C Theurkauf, William, ...... 11 Suo, Bangxia, ...... 596B Thevenon, Dominique, ...... 153, 635B Surette, Michael G., ...... 121 Thomas, Andrew S., ...... 343A Surkova, Svetlana, ...... 756C* Thomas, Graham, ...... 166A Susova, Olga Yu., ...... 340A Thomas, Graham H., ...... 178A Suzanne, Magali, ...... 745A Thomas, John, ...... 129 Suzuki, Takuya, ...... 223A Thomas, John B., ...... 44 Swanson, Christina I., ...... 264C*, 481A Thomas, Sean, ...... 838A Swanson, Selene, ...... 317B 103

Speaker and Author Index

Thomas, Silke, ...... 702C Uyetake, Lyle,...... 284B Thomenius, Michael, ...... 65 Uytterhoeven, Valerie,...... 925A Thompson, Rhea, ...... 20 Thompson, Seth, ...... 735C Thor, Stefan, ...... 695B, 723C V Thornton, Kevin, ...... 924C Thornton, Kevin R., ...... 510C Vaccari, Thomas, ...... 192C, 193A Thummel, Carl, ...... 126 Vachias, Caroline, ...... 169A Thummel, Carl S., ...... 767B, 769A Vähä-Mäkilä, Mari, ...... 616A Thuparani, Manisha, ...... 271A Valentine, Meagan, ...... 159C, 197B* Tian, Rui, ...... 705C* van Bergeijk, Petra, ...... 284B Tibbit, Charlotte, ...... 854B van Bokhoven, Hans, ...... 41 Timmons, Allison, ...... 294C* Vanderzalm, Pam J., ...... 7* Ting, Chau-Ti, ...... 482B Van Doren, Mark, ...... 101, 591C, 592A, 594C Tipping, Marla, ...... 8, 246C Van Goethem, Emeline, ...... 610A Tiyaboonchai, Amita, ...... 883A Vanha-aho, Leena-Maija, ...... 150, 616A* Tjota, Monika, ...... 178A Vanlandingham, Phillip, ...... 696C* Tkachuk, Artem, ...... 380B, 918C van Meyel, Donald, ...... 199A Tkacik, Gasper, ...... 732C Vargas, Eric, ...... 884B Toering Peters, Stephanie, ...... 304A* Vartiainen, Maria, ...... 133, 185B Tokusumi, Tsuyoshi, ...... 892A Vásquez, Constanza, ...... 300C Tokusumi, Yumiko, ...... 892A Vasquez, Stephanie, ...... 766A Tolstorukov, Michael Y., ...... 366C, 381C Vatolina, Tatyana Yu.,...... Plenary Session I (continued) Tolwinski, Nicholas S., ...... 151* Vaughn, Jack C., ...... 795C, 875B Tomancak, Pavel, ...... 117*, 815B Vázquez, Martha, ...... 391A Tomoyasu, Yoshinori, ...... 468C, 473B, 477C, 517A Veelken, Cornelia, ...... 900C Tong, Chao, ...... 200B Veldhuis, James H., ...... 1 Tonkin, Leath A., ...... 114 Velichkova, Michaella M., ...... 149* Toomey, Michelle E., ...... 640A, 641B* Venard, Claire M.-P., ...... 579C* Tootle, Tina L., ...... 98* Venkatesh, Tadmiri, ...... 700A Tosa, Marie, ...... 296B Venken, Koen, ...... 140* Touma, Johnny, ...... 722B* Veraksa, Alexey, ...... 8, 246C* Toups, Melissa A., ...... 495C* Verboon, Jeffrey M., ...... 187A* Tracey, Dan, ...... 22 Verghese, Shlipi, ...... 306C* Tracy, Charles, ...... 52 Verheyen, Esther, ...... 152, 333C Tran, Susan L., ...... 201C Verma, Akanksha, ...... 330C* Trautman, Jon, ...... 917B Vermaak, Danielle, ...... 367A Traynis, Ilana, ...... 265A Verstreken, Patrik, ...... 925A Trejo, Humberto, ...... 40 Veverytsa, Lyubov, ...... 664A* Troutwine, Benjamin, ...... 680B* Vibranovski, Maria, ...... 33* Trujillo, Gloriana, ...... 257B* Vicoso, Beatriz, ...... 496A* Tsai, Amy, ...... 706A Vied, Cynthia, ...... 898A Tsai, Jui-He, ...... 370A* Vigoder, Felipe M., ...... 652A Tsechpenakis, Gavriil, ...... 945C* Vigoreaux, Jim,...... 647B Tsechpenakis, Gavril, ...... 938B VijayRaghavan, K., ...... 136 Tsoi, H., ...... 422B Villa-Cuesta, Eugenia, ...... 451A, 763A Tsuda, Leo, ...... 305B*, 431B, 712A Villalta, Jacqueline E., ...... 114 Tsui, Chiahao, ...... 112, 810C Vinay Pandey, Ram, ...... 929B Tsurumi, Amy, ...... 757A* Vincent, Alain, ...... 615C Turki-Judeh, Wiam, ...... 844A Vinokur, Marianna, ...... 435C Tutor, Antonio S., ...... 554B Visk, DeeAnn, ...... 507C Tyler, Anna L., ...... 912C Visk, DeeAnn W., ...... 463A* Vitalini, Michael W., ...... 343A, 887B* U Vlachos, Stephanie, ...... 893B* Vlcek, Daniel, ...... 252C Vogler, Georg, ...... 566B* Udel, Christian, ...... 232A Volk, Talila, ...... 549C Udpa, Nitin, ...... 507C Volkan, Pelin C., ...... 24, 711C* Ueno, Naoto, ...... 51 Volovitch, Michel, ...... 237C Uhler, Maria, ...... 315C Volpi, Silvia, ...... 607A* Ukken, Fiona P., ...... 186C* von Kalm, Laurence, ...... 248B, 419B, 556A Uliczka, Karin A., ...... 639C* Vorontsova, Julia, ...... 754A Ulvila, Johanna, ...... 616A Vrontou, Eleftheria, ...... 68 Ulvklo, Carina, ...... 695B, 723C* Vuoksio, Milka, ...... 616A Umeh, Maxine, ...... 866B* Vurens, Gerard,...... 735C Umulis, David, ...... 730A Umulis, David M., ...... 113* Unckless, Robert, ...... 506B* Upadhyai, Priyanka, ...... 847A* Utreja, Suruchi, ...... 435C 104

Speaker and Author Index

W Wasserman, Steven, ...... 613A Watanabe, Toshiaki, ...... 9 Wawersik, Matthew, ...... 142*, 957C Wagner, Eric, ...... 877A Wayne, Marta L., ...... 811A Wajda, Matthew, ...... 647B Weake, Vikki M., ...... 115, 376A Wakimoto, Barbara T., ...... 607A Weasner, Bonnie, ...... 744C* Waldron, Evan J., ...... 853A Weavers, Helen, ...... 587B* Walker, James, ...... 352A Webber, Jemma L.,...... 848B* Walker, Jim, ...... 110 Weber, Ursula, ...... 158B Wallace, Douglas C., ...... 127 Webster, Claire L., ...... 627C Wallace, Nneka, ...... 315C Webster, Kyle, ...... 80 Wallrath, Lori L., ...... 343A, 887B Weckerle, Frank, ...... 722B Wan, Jijun, ...... 669C Weeks, Madelyn, ...... 779B* Wan, K., ...... 836B Wehrli, Marcel, ...... 155* Wan, Kenneth, ...... 136, 939C Wei, Ho-Chun, ...... 104 Wan, Kenneth H., ...... 946A* Weiler, Karen S., ...... 571A Wan, Ping, ...... 174C, 222C* Weiss, Miriam, ...... 146 Wang, Biao, ...... 129* Weiszmann, Richard, ...... 921C, 946A Wang, Bing, ...... 200B, 886A Welch, Elaine, ...... 294C Wang, Chao, ...... 608B* Welch, William, ...... 137 Wang, Chao-Yung, ...... 794B Welch, William P., ...... 935B Wang, Ching-Tzu, ...... 794B Weld, Holli A., ...... 108 Wang, Dong, ...... 134 Wells, Richard E.,...... 99* Wang, Hao, ...... 226A Welte, Michael A., ...... 201C, 209B*, 327C Wang, Hongfei, ...... 266B Wemg, Zhiping, ...... 11 Wang, Hongyan, ...... 699C, 724A* Wen, Yuhui, ...... 698B* Wang, Horng-Dar, ...... 794B* Weng, Katherine A., ...... 318C* Wang, Hsiang-Yu, ...... 444C* Weng, Mo, ...... 725B* Wang, Hui, ...... 911B Wennemuth, Nadine, ...... 897C Wang, Ing-Nang, ...... 631A Wentzell, Jill, ...... 424A Wang, Jian, ...... 780C Wepf, Alexander, ...... 325A Wang, Jianquan, ...... 94 Wesolowska, Natalia, ...... 355A Wang, Jie, ...... 11 Wessells, Robert, ...... 130 Wang, Jun, ...... 33 Westwood, J. Timothy, ...... 41 Wang, Lan-Hsin, ...... 307A* White, Anne, ...... 272B Wang, Lei , ...... 128* White, Benjamin, ...... 659B, 709A Wang, Liqun, ...... 579C White, Kevin, ...... 116, 828C Wang, Long Qin, ...... 598A White, Kevin P., ...... 765C Wang, Minpei, ...... 419B* White, Kristin, ...... 65, 296B, 717C Wang, Mou-Chun, ...... 498C White-Cooper, Helen, ...... 604A, 814A* Wang, N., ...... 658A Whitfield, Zachary J., ...... 319A* Wang, Qin, ...... 286A Whitworth, Alexander, ...... 436A Wang, Qun,...... 803B* Whitworth, Cale D., ...... 592A* Wang, Shanzhi, ...... 877A* Wichmann, Carolin, ...... 691A, 705C Wang, Shiuan, ...... 290B* Wiek, Robert, ...... 42 Wang, Shu, ...... 31 Wieschaus, Eric F., ...... Plenary Session II, 208A, 732C Wang, Shu-Huei, ...... 760A Wightman, Patrick J., ...... 464B* Wang, Simon, ...... 706A* Wildonger, Jill, ...... 18 Wang, Sophia Ju-Yu, ...... 570C Wilhelm, James, ...... 867C, 870C Wang, Tao, ...... 295A Wilhelm, James E., ...... 14* Wang, Wei, ...... 720C Williams, Janice A., ...... 178A Wang, Xiaobo, ...... 91 Williams, Julie, ...... 676A Wang, Yajie, ...... 286A Williams, Michael, ...... 119 Wang, Yan, ...... 173B Williamson, W. Ryan, ...... 210C*, 787A Wang, Yang, ...... 461B Wilson, Clive, ...... 47* Wang, Ye, ...... 882C Wilson, Heather, ...... 631A* Wang, Yiwen, ...... 884B Wilson, Rachel, ...... 672C Wang, Yi-Yun, ...... 794B Wingert, Lindsey, ...... 894C* Wang, Yue, ...... 720C Witsell, Alice, ...... 265A* Wang, Zhaohui, ...... 596B Wittkopp, Patricia J., ...... Plenary Session I (continued), 483C Wang, Zhe, ...... 286A, 660C Wo, Luyi, ...... 497B* Wang, Zhi, ...... 630C Wodarz, Andreas, ...... 164B, 205A Wangler, Michael, ...... 420C, 445A* Wolfe, Scot, ...... 804C Ward, Robert, ...... 161B Wolfner, Mariana, ...... 586A Warner, Margaret, ...... 137 Wolfner, Mariana F., ...... 103, 122, 486C, 527B, 582C, 653B Warrick, John, ...... 438C Wong, Adam CN, ...... 623B Warrick, John M., ...... 423C, 441C, 442A Wong, C. H., ...... 422B Warrington, Samantha, ...... 157A Wong, Christina,...... 136 Wasbrough, Elizabeth, ...... 36 Wong, Karen M., ...... 541A* Washburn, Michael, ...... 317B Wood, Cricket, ...... 600C Washburn, Michael P., ...... 115, 376A Wood, Jason, ...... 763A 105

Speaker and Author Index

Workman, Jerry L., ...... 115, 376A Yang-Zhou, Donghui, ...... 951C*, 952A Worley, Kim, ...... 928A Yao, Ai Y., ...... 716B* Wotton, Karl, ...... 753C Yao, Chi-Kuang, ...... 67* Wu, C. C., ...... 422B Yasuhi, Hiromi, ...... 601A Wu, Chao-ting, ...... 393C Yates III, John,...... 129 Wu, Chun-Fang, ...... 660C Yatsenko, Andriy, ...... 146 Wu, C.-Ting, ...... 384C Yavatkar, Amar, ...... 910A Wu, Juan, ...... 178A Ye, Jieping, ...... 748A Wu, Lijie, ...... 266B Yenerall, Paul, ...... 498C* Wu, Qinghua, ...... 372C Yew, Joanne, ...... 784A Wu, Wei, ...... 21* Yi, Shuxia, ...... 795C Wu, Yimin, ...... 84 Yoder, Christine, ...... 382A Wu, Yuan-Qing, ...... 928A Yoo, Na-Eun Christine, ...... 476B Wu, Yujane, ...... 173B Yoo, Youngdong, ...... 346A Wu, Zhuhao, ...... 699C Yoon, Petros, ...... 39 Wunderlich, Zeba, ...... 106*, 520A Yoon, Wan H., ...... 13* Yorimitsu, Takeshi, ...... 741C Yoshiyama, Takuji, ...... 472A X Young, Robert, ...... 854B Younger, Susan, ...... 18 Younglan, Kim, ...... 395B* Xia, Fan, ...... 757A Yu, Albert, ...... 326B Xiao, Hailian, ...... 540C Yu, Amy Marie, ...... 43 Xiao, Hui, 610A Yu, Bangning, ...... 72 Xie, Tiao, . 133 Yu, Charles, ...... 136, 939C, 946A Xie, Weiwu, ...... 388A*, 841A Yu, Fengwei, ...... 699C* Xie, Xiao, . 735C Yu, Jai Y., ...... 68 Xie, Xie, ...... 859A* Yu, Kweon, ...... 414C, 626B Xie, Xuanhua, ...... 231C* Yu, Qin, ...... 694A* Xing, Yalan, ...... 271A*, 361A Yu, Stephanie,...... 393C Xiong, Bo, 224B, 420C, 446B Yu, Yanxun V., ...... 209B Xu, Jia, ...... 11 Yuan, Lei, ...... 748A* Xu, Mu, ...... 564C Yuan, Qing, ...... 286A Xu, Peng, . 567C* Yuan, Rong, ...... 277A Xu, Rui-Ming, ...... 570C Yucel, Gözde, ...... 476B Xu, Tian, .. 102 Yue, Tao, ...... 886A Xu, Zhe, ... 55, 834C* Yuh, Chiou-Hwa, ...... 794B Xue, Chenghai, ...... 851B Yun, Amber, ...... 657C Xue, Jin, ...... 507C Yun, Eun-Young, ...... 886A Xue, Lei, ...... 235A Yun Doo, Chung, ...... 395B

Y Z

Yacobi-Sharon, Keren, ...... 291C* Zamore, Phillip D., ...... 871A Yadlapalli, Swathi, ...... 147* Zanet, Jennifer, ...... 829A Yagi, Ryohei, ...... 932B Zarnescu, Daniela C., ...... 903C Yakoby, Nir, ...... 56, 191B Zatsepina, Olga, ...... 754A Yakubovskaya, Marianna G., ...... 340A Zeidler, Martin P., ...... 46*, 99, 212B Yamada-Mabuchi, Megumu, ...... 296B, 717C Zeng, Xiankun, ...... 895A*, 901A Yamamoto, Akihiko H., ...... 678C Zhai, Bo, ...... 946A Yamamoto, Daisuke, ...... 650B Zhai, Grace, ...... 938B Yamamoto, Rochele, ...... 766A Zhai, R. Grace, ...... 698B Yamamoto, Shinya, ...... 224B, 226A, 420C, 446B Zhai, Zongzhao, ...... 297C* Yamasaki, Yasutoyo, ...... 712A* Zhang, Bing, ...... 137, 462C, 696C, 727A, 935B Yamashita, Yukiko, ...... 147 Zhang, Bingqing, ...... 292A* Yamashita, Yukiko M., ...... 883A Zhang, Can, ...... 936C* Yan, Rihui, ...... 320B*, 370A Zhang, Jianhua, ...... 401B Yan, Yan, ...... 87 Zhang, Jie, ...... 848B Yang, Chih-Sheng, ...... 276C* Zhang, Ke, ...... 224B, 420C, 446B* Yang, Chun-Yen, ...... 427A Zhang, Linbin, ...... 540C Yang, Hao, ...... 371B* Zhang, Liping, ...... 588C* Yang, Jing, ...... 706A Zhang, Qiao, ...... 580A* Yang, Jr-Shiuan, ...... 256A Zhang, Xiaomeng, ...... 4 Yang, Julie T., ...... 795C Zhang, Yan, ...... 429C, 439A, 937A* Yang, L., ...... 836B Zhang, Yanping, ...... 277A Yang, Meng, ...... 64 Zhang, Yi, 704B Yang, Taehong, ...... 210C Zhang, Ying, ...... 115 Yang, Xiao-cui, ...... 272B Zhang, Yong, ...... 116, 467B Yang, Yong, ...... 64* Zhang, Yong Q., ...... 704B, 716B Yang, Yunyi, ...... 475A 106

Speaker and Author Index

Zhang, Yong Qing, ...... 705C Zhang, Yu, ...... 926B Zhang, Zhi, ...... 403A* Zhao, Huiwen, ...... 465C* Zhao, Keji, ...... 379A Zhao, Shaowei, ...... 596B Zhao, Yun, ...... 200B Zheng, Li, ...... 130 Zheng, Qi, ...... 884B* Zheng, Zhiyu, ...... 901A Zhimulev, Igor, ...... 364A Zhimulev, Igor F., ...... Plenary Session I (continued) Zho, Qi, ...... 514A Zhong, Mei, ...... 9 Zhou, B., ...... 109 Zhou, Dan, ...... 463A, 465C, 507C* Zhou, Huiqing, ...... 41 Zhou, Jun, ...... 897C Zhou, Lei, ...... 379A, 936C Zhou, Leming, ...... 498C, 957C Zhou, Lili, ...... 599B Zhou, Liya, ...... 720C Zhou, Mengning, ...... 255C Zhou, Pingkun, ...... 286A Zhou, Qi, ...... 490A, 499A* Zhou, Rui, ...... 952A* Zhou, Xiaobo, ...... 911B Zhou, Yiyun, ...... 247A* Zhouzheng, Sophie, ...... 255C Zhu, Chen-Tseh, ...... 763A* Zhu, Dianhui, ...... 25 Zhu, Sijun, 1 ...... 8* Zhu, Xianmin, ...... 835A* Zhuo, Ran, ...... 234C Ziauddin, Junaid, ...... 123* Zieba, Jennifer, ...... 765C Zimmerman, Sandra, ...... 254B Zimmerman, Sandra G., ...... 581B* Zipursky, Larry, ...... 21 Zirzow, Amanda C., ...... 774C* Zitserman, Diana, ...... 226A Zuberova, Monika, ...... 450C Zurita, Mario, ...... 391A Zyaan, Ola, ...... 780C

107

Keyword Index

The following index is composed of keywords selected by presenting authors from a list in the Conference Call for Abstracts. Abstract program numbers follow each keyword.

Cell biology & signal transduction receptor tyrosine kinase/phosphatase 244A 245B 246C 247A autophagy rho gtpases 149 248B 249C

cell adhesion rhodopsin phosphorylation 233B 236B

cell competition secretion 238A 250A 251B 252C

cell polarity selective autophagy 86 157A 158B 159C 160A 161B 162C 163A 164B 165C 166A 167B 153 168C 169A 170B 171C

wingless cytoskeleton 151 152 155 253A 254B 255C 256A 257B 83 85 87 172A 173B 174C 175A 176B 177C 178A 179B 180C 181A

182B 183C 184A 185B 186C 187A Cell cycle and checkpoints detoxification 234C activators/coactivators 272B dorsal closure 241A APC 258C dpp 188B 189C 190A 191B checkpoint 60 259A 260B 261C 262A endocytosis 192C 193A 194B 195C 196A 197B developmental modulation 61 62 263B 264C extracellular homeoprotein 237C DNA repair 265A glycosphingolipids 240C DNA replication 63 266B 267C 268A hedgehog 198C 199A 200B kinase/phosphatase/cyclin 269B 270C 271A hippo pathway 239B Cell death intracellular transport apoptosis 84 90 201C 202A 203B 204C 205A 206B 207C 208A 209B 210C 286A

JAK/STAT apoptosis, endocycle 150 211A 212B 213C 214A 215B 292A

JNK apoptosis, ER stress, autophagy, neurons 235A 288C

migration autophagy 216C 217A 218B 219C 220A 221B 222C 273C

networks caspases 242B 274A 275B 276C

notch cell death in cell competition 154 156 223A 224B 225C 226A 227B 228C 229A 230B 231C 287B

RAS/MAPK signaling compensatory proliferation 232A 290B

RBF death mutants/genes 243C 277A 278B 279C 280A 281B 282C 283A 284B 108

Keyword Index

inhibitors of apoptosis (iaps) chromosome dynamics 64 285C 384C mitochondria DNA methylation 65 289A 383B non apoptotic cell death heterochromatin 291C 76 357C 358A 359B 360C 361A 362B 363C 364A 365B 366C 367A 368B 369C 370A 371B physiological apoptosis 66 293B 294C histone variants and modifications 77 80 115 372C 373A 374B 375C 376A transcriptional regulation 295A 296B 297C insulators/boundary elements 78 377B 378C 379A 380B 381C Cell division and growth control lamina 386B cell competition 298A 299B noncoding RNA 82 cell growth 3 300C 301A 302B 303C 304A 305B 306C 307A polycomb/trithorax complexes 81 389B 390C 391A 392B 393C 394A 395B centrosome 308B 309C 310A 311B regulation of RNAi 388A compensatory proliferation 326B remodeling complexes 396C 397A cytokinesis 2 312C 313A RNA silencing 382A DNA polymerase 330C telomere 385A 387C embryonic development 327C transvection 79 growth 328A Drosophila models of human diseases insulin addiction 314B 398B 399C

meiosis asthma 315C 316A 317B 318C 319A 320B 453C

mitosis cancer 1 321C 322A 323B 324C 44 45 46 47 48 400A 401B

phospholipid signaling cardiovascular 329B 49 50 402C 403A

tissue growth cell polarity, retinitis pigmentosa 4 5 6 331A 332B 333C 334A 335B 336C 337A 458B

translational control developmental disorders 325A 51 52 404B 405C 406A 407B 408C 409A 410B 411C

tumor suppressors and oncogenes diabetes and obesity 7 8 338B 339C 340A 341B 342C 412A 413B 414C 415A

Chromatin and epigenetics disorder of metabolism 464B chromatin assembly 343A 344B 345C 346A drug discovery 39 40 416B 417C 418A 419B chromatin structure 75 347B 348C 349A 350B 351C 352A 353B 354C 355A 356B 109

Keyword Index

epilepsy evolution and development 459C 31 32 34 35 36 466A 467B 468C 469A 470B 471C 472A 473B 474C 475A 476B 477C 478A 479B fragile-x, grooming, climbing, monoamine 462C evolution of behavior 505A homeostasis 456C gene expression 504C hyperoxia 465C genome adaptation 507C hypoxia 448A 463A genome evolution 10 26 28 33 38 116 480C 481A 482B 483C 484A 485B 486C 487A intellectual disability 488B 489C 490A 491B 492C 493A 494B 495C 496A 497B 498C 499A 41 intralocus sexual antagonis, gene duplication lamins 503B 460A neo-sex chromosome metabolism 501C 451A phylogenetics muscle 508A 509B 455B population variation muscular dystrophy 25 29 510C 511A 512B 513C 514A 515B 516C 517A 518B 519C 520A 454A 521B 522C 523A 524B myopathy quantitative traits 461B 27 37 525C 526A 527B 528C 529A 530B 531C 532A 533B 534C 535A 536B 537C 538A neural degeneration 420C 421A 422B 423C 424A 425B 426C 427A 428B 429C 430A 431B speciation 432C 433A 434B 435C 436A 437B 438C 439A 440B 441C 442A 443B 30 539B 540C 541A 444C 445A 446B taxonomy neuromuscular disorders 500B 42 trade-off ortholog 122 452B virus reprotoxic effect 506B 447C Gametogenesis and organogenesis research resource

457A accessory gland proteins 586A seizure disorders 449B cell polarity and morphogenesis 583A stress response 450C dosage compensation 114 542B 543C telomere 43 ectodermal derivatives 89 99 544A 545B 546C 547A 548B Educational Initiatives extracellular matrix/cell adhesion 96 549C 550A 551B 552C 553A college/university curriculum

953B 954C 955A 956B 957C 958A glycosylation

588C Evolution and quantitative genetics imaginal disc morphogenesis adaptation 102 554B 555C 556A 502A

110

Keyword Index

mesodermal derivatives Neural physiology and behavior 100 557B 558C 559A 560B 561C 562A 563B 564C 565A 566B 567C

addiction metamorphosis 680B 585C

aggression

642C 643A morphogenesis circadian rhythms 587B 71 644B

myogenesis courtship and mating 584B 70 645C 646A 647B 648C 649A 650B 651C 652A 653B 654C 655A

oogenesis egg-laying 91 94 95 97 98 568A 569B 570C 571A 572B 573C 574A 575B 576C 671B 577A 578B 579C 580A 581B

ethology pre-gametogenic germ cell development 672C 589A

homeostasis sex determination 656B 101 590B 591C 592A

hormones sex-specific traits and molecules 657C 658A 659B 92 103 593B 594C

learning/memory sperm storage 68 69 660C 661A 662B 582C

locomotion spermatogenesis 670A 678C 93 104 595A 596B 597C 598A 599B 600C 601A 602B 603C 604A

605B 606C 607A 608B locomotor

679A Immunity and pathogenesis microsurgery cell death 677B 634A neuropeptides cellular immunity 663C 664A 609C 610A 611B 612C 613A 614B 615C 616A neurotransmitters host/pathogen interaction 665B 666C 667A 668B 669C 119 120 121 617B 618C 619A 620B 621C 622A 623B 624C 625A 626B 627C 628A 629B 630C 631A new method for conditional behavioral modification 72 humoral immunity 124 632B 633C nociception 673A priming 123 phototaxis 674B stem cells 637A sensory 73 681C 682A 683B 684C 685A 686B 687C 688A 689B 690C toll pathway 636C sleep 676A transcriptional regulation 638B 639C synapse 67 74 691A ubiquitin 635B temperature preference behavior 675C Wolbachia 125 640A 641B Neurogenetics and neural development

axon guidance 20 692B 693C 694A

111

Keyword Index

CNS wing disc 695B 696C 59 758B 759C 760A corazonin, neuropeptide, evolution Physiology and aging 715A

aging cytoskeleton 781A 716B dendrites autophagy 21 22 88 697A 698B 699C 782B glia dietary restriction 19 700A 701B 702C 761B 762C 763A neuronal morphogenesis drug response 16 703A 704B 705C 706A 783C neuronal specification endocrine function 17 118 707B 708C 709A 710B 711C 712A 764B 765C programmed cell death juvenile hormone 717C 780C sensory metabolism 24 718A 126 127 129 130 131 766A 767B 768C 769A 770B 771C 772A stem cells nutrient sensing 18 719B 720C 721A 722B 723C 724A 725B 132 773B 774C synaptic plasticity nutrition 713B 775A 776B 777C 778A 779B synaptogenesis oxidative damage 23 726C 727A 728B 729C 785B 786C trophic factors pheromone 714C 784A

Pattern Formation physiology of adult organs 128 787A 788B 789C 790A 791B axis specification 53 54 57 730A 731B 732C 733A 734B stress response 792C 793A 794B cell migration and motility 735C 736A RNA biology

compartments and boundaries miRNA 55 58 737B 12 13 849C 850A 851B 852C 853A development stage annotation mRNA translation 748A 857B eye disc non-coding transcripts 738C 739A 740B 741C 742A 743B 744C 854B intercalation p-bodies 746B 856A leg disc piRNAs 745A 858C muscle specification RNA binding proteins 747C 14 860B 861C 862A oogenesis RNA editing 56 855C segmentation RNA elongation and stability 113 749B 750C 751A 752B 753C 754A 755B 756C 757A 863B 864C 865A 866B

112

Keyword Index

RNA localization somatic stem cell 15 867C 868A 869B 870C 141 142 143 144 902B 903C 904A 905B 906C 907A

RNAi (RNA interference) Techniques and functional genomics 871A

antibody production small RNAs 934A 9 11 872B cell-specific gene expression splicing and its regulation 935B 873C 874A 875B 876C 877A computational analyses transfer RNA 135 139 908B 909C 910A 911B 912C 913A 914B 915C 859A epigenetics Regulation of gene expression 936C activators/coactivators expression vector 110 111 795C 796A 797B 798C 799A 800B 801C 802A 803B 937A alternative splicing FRT/FLP, GAL4/UAS, GAL4 restriction, GAL80 836B 137 computational models of transcription regulation gene disruption and targeting 838A 134 140 916A 917B 918C 919A core promoters and general transcription factors genetic manipulation technique 105 804C 805A 806B 807C 808A 809B 810C 811A 812B 813C 814A 932B dosage compensation microarrays 841A 920B ecdysone microfluidics 837C 933C enhancers microscopy 106 107 108 109 815B 816C 817A 818B 819C 820A 821B 822C 823A 117 138 921C 824B 825C 826A 827B 828C 829A 830B 831C 832A 833B 834C 835A next-generation sequencing evolution of transcription regulation 922A 923B 924C 925A 926B 927C 928A 929B 840C proteomics expression networks 136 938B 939C 940A 941B 942C 943A 944B 945C 946A 839B real-time 3D tracking, multi camera system repressors/corepressors 930C 112 842B 843C 844A 845B 846C 847A 848B recombination systems Stem cells 947B 948C 949A

germline stem cell research resources 146 147 878B 879C 880A 881B 882C 883A 884B 931A intestinal stem cell; enteroblast; gal4 lines RNAi 895A 133 950B 951C 952A maintenance 145 885C 886A 887B niche 148 888C 889A 890B 891C 892A 893B 894C

signaling 896B 897C 898A 899B 900C 901A

113

FlyBase Genetic Index to Abstracts

This is an index of genes mentioned in the abstracts. The current FlyBase-approved gene symbol is given in each case; non- current symbol synonyms or full names used in the abstracts are not indexed.

The index was prepared computationally based solely on the FBgn & gene symbol information provided by authors during abstract submission. FlyBase has performed a cross-check between the FBgn and gene symbol provided to ensure the intended gene is indexed. FlyBase is not responsible for any omissions from the index where authors did not provide information, nor for any incorrect indexing where genes stated to feature in an abstract do not actually appear.

Indexed terms are in bold. Numbers following each term refer to abstract program numbers.: 1--156 are platform presentations and 157--958 are poster presentations.

-Adaptin ...... 195C bab2 ...... 888C CG5642 ...... 365B -Cat ...... 155, 233B bam ...... 35, 879C, 907A CG5871 ...... 774C ggt-II ...... 224B baz ...... 162C, 583A, 739A CG5932 ...... 126 Tub60D ...... 702C bcd ...... 732C, 809B CG6509 ...... 207C Tub37C ...... 316A bchs ...... 782B CG6789 ...... 598A 14-3-3 ...... 616A bi ...... 59, 473B CG7172 ...... 362B ab ...... 473B, 477C, 759C blot ...... 222C CG7995 ...... 464B abd-A ...... 824B bnl ...... 216C CG9139 ...... 48 Abd-B ...... 297C boi ...... 199A CG9996 ...... 230B Abi ...... 616A bon ...... 54, 650B Chc ...... 250A Abl ...... 566B, 693C br ...... 107, 252C, 556A, 632B, 818B, 837C Chd1 ...... 349A ac...... 712A brat ...... 141 CHES-1-like...... 100, 835A Ace ...... 713B brk ...... 59, 817A, 818B chic ...... 173B achi ...... 814A brm ...... 391A chico ...... 776B, 782B Acp26Aa ...... 103, 653B brn ...... 240C chinmo ...... 902B Acp36DE ...... 103 brp ...... 691A Chmp1 ...... 197B Acp70A ...... 103 Bruce ...... 274A chn ...... 712A Acsl ...... 704B bs ...... 555C, 737B Chro ...... 363C Act5C ...... 91 bsk ...... 119, 124, 190A, 241A, ci ...... 199A Adar ...... 430A ...... 283A, 294C, 299B cic ...... 809B Adgf-A ...... 450C bss ...... 459C Cka ...... 950B AGO1 ...... 575B Bub3 ...... 261C Clc ...... 195C AGO2 ...... 627C burs ...... 658A, 659B, 709A cnn ...... 309C, 739A AGO3 ...... 10 bwk ...... 581B comr ...... 814A Akt1 ...... 772A c ...... 958A Corp ...... 277A ald ...... 315C cac ...... 691A cort ...... 319A Aldh-III ...... 770B cact ...... 636C cos ...... 198C aly ...... 814A CaMKII ...... 276C, 706A Cp190 ...... 862A Antp ...... 824B can ...... 814A cpa ...... 334A, 616A aop ...... 725B Cap-D3 ...... 110 cpb ...... 334A ap ...... 557B, 707B, 708C Capr ...... 61, 905B crb ...... 171C, 458B, 547A, 739A, 740B AP-1 ...... 250A, 420C cas ...... 719B, 832A, 910A CrebA ...... 680B, 697A AP-47 ...... 250A CASK ...... 679A CrebB-17A ...... 680B Apc ...... 254B caup ...... 473B, 557B cry ...... 651C Apc2 ...... 141, 155, 254B, 255C, 324C cav ...... 355A, 385A ct ...... 88, 297C, 379A, 697A, 703A aPKC ...... 160A, 162C, 323B, 583A Ccap ...... 709A cta ...... 85 Appl ...... 434B Cdc42 ...... 566B, 944B Cul-3 ...... 274A, 902B apt ...... 13, 213C, 891C Cdk5 ...... 66 cv ...... 473B ara ...... 473B Cdk8 ...... 803B cv-2 ...... 730A Arc1 ...... 865A Ced-12 ...... 610A CycC ...... 803B Argk ...... 484A CG10673 ...... 300C Cyp12d1-d ...... 577A argos ...... 823A CG10990 ...... 878B Cyt-c-d...... 289A Ark ...... 282C CG11699 ...... 770B da ...... 802A arm ...... 155, 255C CG11864 ...... 103 DAAM ...... 89 armi ...... 9, 869B CG12442 ...... 814A dac ...... 707B Arr1 ...... 236B CG14225 ...... 150 Dap160 ...... 67 Arr2 ...... 236B CG14508 ...... 289A Dat ...... 958A asun ...... 93 CG14709 ...... 785B dati ...... 655A Atg1 ...... 273C CG15609 ...... 23, 226A, 227B, 616A dco ...... 651C Atg13 ...... 273C CG16778 ...... 645C Dcr-1 ...... 575B Atg8a ...... 776B, 782B CG17184 ...... 84 Dcr-2 ...... 627C, 871A ato ...... 802A CG1950 ...... 598A Dg ...... 169A, 454A Atp ...... 404B CG2765 ...... 616A Dhc64C ...... 209B ATP7 ...... 456C CG2789 ...... 127 dimm ...... 707B aub ...... 10, 570C CG30115 ...... 248B dl ...... 53, 246C, 809B, 817A, 914B, 933C Axn ...... 155 CG32418 ...... 301A Dl ...... 224B, 230B, 622A, 725B, 737B bab1 ...... 888C CG4701 ...... 597C dlg1 ...... 706A 114

FlyBase Genetic Index to Abstracts

Dmn ...... 606C fray ...... 656B Kdm4A ...... 357C DNApol-180 ...... 268A fried ...... 335B kek1 ...... 737B DNApol- ...... 268A fru ...... 70, 650B ken ...... 13 DNApol- ...... 330C fs(1)Yb ...... 9 key ...... 620B DNApol- ...... 60 ft ...... 239B Khc ...... 209B, 702C, 740B Doa ...... 396C ftz ...... 470B, 750C kirre ...... 247A dome ...... 212B ftz-f1 ...... 750C kis ...... 20 dor ...... 420C futsch ...... 421A klar ...... 209B dp ...... 873C fwd ...... 158B klhl10 ...... 274A Dp ...... 263B fz ...... 159C, 163A kn ...... 88, 473B, 558C, 707B dpn ...... 18 fzy ...... 885C kni ...... 473B, 759C, 809B, 842B dpp ...... 54, 59, 148, 190A, 730A, gbb ...... 708C Kr ...... 557B ...... 737B, 758B, 760A, 818B, 927C gce ...... 837C Krn ...... 244A Dpt ...... 40 Git ...... 705C krz ...... 246C Dr ...... 109, 557B Gl ...... 74 kst ...... 166A Drak ...... 176B Gmd ...... 896B l(1)G0144 ...... 224B drd ...... 578B, 585C Gprk1 ...... 236B l(2)37Cc ...... 304A Dredd ...... 124 Gr21a ...... 689B l(2)gl ...... 145, 160A, 252C, Dref ...... 3 Gr61a ...... 690C ...... 299B, 400A, 907A Drip ...... 526A Gr63a ...... 689B lap ...... 67 drpr ...... 294C Gr64a ...... 690C lark ...... 574A ds ...... 239B Gr64b ...... 690C lea ...... 692B Dscam ...... 948C Gr64c ...... 690C Lhr ...... 30, 368B dsh ...... 163A Gr64d ...... 690C lig ...... 325A Dsor1 ...... 232A Gr64e ...... 690C lig3 ...... 265A dsx ...... 70, 590B, 592A, 831C Gr64f ...... 690C Lis-1 ...... 93 dtr ...... 683B Gr66a ...... 773B lkb1 ...... 169A dup ...... 359B grh ...... 910A lmd ...... 247A Dys ...... 454A grim ...... 296B lok ...... 60, 259A E(tc) ...... 387C grk ...... 244A lola ...... 709A E(var)3-9 ...... 571A gt ...... 389B lolal ...... 888C E(z) ...... 363C, 389B Gyk ...... 464B LpR1 ...... 771C E2f ...... 263B, 305B, 803B h ...... 712A, 842B LpR2 ...... 771C E2f2 ...... 263B halo ...... 201C lwr ...... 391A Eaat1 ...... 669C hb ...... 106, 389B lz ...... 92, 481A eag ...... 656B Hdc ...... 667A Mad ...... 341B, 708C, 933C eas ...... 459C hh ...... 58, 198C, 199A, 682A, 892A, 927C mago ...... 232A ebi ...... 243C, 305B, 431B HipHop ...... 355A, 385A magu ...... 59 EcR ...... 47, 252C, 314B, 765C hipk ...... 152, 333C mahj ...... 299B Egfr ...... 170B, 244A, 548B, 737B, 760A hkb...... 809B mamo ...... 709A egg ...... 366C Hmr ...... 368B mbc ...... 83 egh ...... 240C, 649A Hop ...... 46 mbt ...... 721A egr ...... 682A HP6 ...... 367A Mcm10 ...... 268A, 365B eIF-4E ...... 856A hpo ...... 7, 334A, 886A Mcm2 ...... 268A eIF4AIII ...... 232A Hr39 ...... 92 Mcm5 ...... 268A Eip74EF ...... 252C, 837C Hr4 ...... 764B Mcr ...... 161B Eip75B ...... 709A Hr46 ...... 709A Med ...... 54 Eip78C ...... 632B Hr96 ...... 126 Mef2 ...... 115 Eip93F ...... 632B hth ...... 824B Mekk1 ...... 66 emb ...... 422B hts ...... 706A meso18E ...... 115 emc ...... 712A ial ...... 2 Met ...... 837C en ...... 237C, 816C ihog ...... 199A Mhc ...... 172A ena ...... 217A Ilp2 ...... 398B, 663C, 776B mib2 ...... 247A endoA ...... 67 Ilp6 ...... 398B mip40 ...... 814A eve ...... 826A, 833B imd...... 124, 620B Mipp1 ...... 545B ewg ...... 562A ImpL2 ...... 663C Mipp2 ...... 545B exd ...... 824B Incenp ...... 2 mir-279 ...... 13 ey ...... 802A, 927C InR...... 398B, 765C, 776B mir-7 ...... 849C eya ...... 707B inv ...... 816C mir-8 ...... 853A faf ...... 54 Ipk1 ...... 545B mir-9a ...... 849C feo ...... 2 Ipk2 ...... 545B mirr ...... 827B fkh ...... 812B Ir ...... 758B Mlc2 ...... 647B fln ...... 647B Irk2 ...... 758B Mlf ...... 115 flower ...... 67 Irk3 ...... 758B mmy ...... 189C flr ...... 174C Jhe ...... 649A mod(mdg4) ...... 862A flw ...... 177C JhI-1 ...... 859A Moe ...... 574A Fmr1.... 61, 325A, 411C, 716B, 903C, 905B Jra ...... 190A, 431B ms(3)K81...... 355A, 385A Fmrf ...... 707B, 708C jumu ...... 100, 835A msn ...... 96 fog ...... 85 kat-60L1...... 22 Mtk ...... 40 for ...... 770B kay ...... 644B Mtp ...... 544A foxo ...... 314B KCNQ ...... 49, 791B mu2 ...... 354C 115

FlyBase Genetic Index to Abstracts

mus209 ...... 268A Prx5 ...... 626B Sh ...... 656B mute ...... 559A Psc ...... 393C shark ...... 581B mxc ...... 589A Psf1 ...... 268A shg ...... 168C, 233B, 622A Myb ...... 689B Psf2 ...... 259A, 268A shi ...... 67, 195C Myd88 ...... 620B Psf3 ...... 268A skl ...... 296B Myo31DF ...... 168C psq ...... 888C sl ...... 329B mys ...... 95, 559A ptc ...... 198C, 199A Sld5 ...... 268A N ...... 58, 154, 160A, 224B, Pten ...... 342C slo ...... 680B ...... 225C, 230B, 481A, 507C, Ptth ...... 764B slou ...... 109, 557B ...... 601A, 725B, 737B, 823A, 927C puc ...... 294C slow ...... 553A n-syb ...... 787A Pvf2 ...... 561C Smc5 ...... 76 nab ...... 910A Pvf3 ...... 561C smet ...... 683B nau ...... 558C Pvr ...... 561C Smg1 ...... 864C, 865A Nc ...... 276C, 282C Pxd ...... 658A Smg5 ...... 865A Ncc69 ...... 656B Pxt ...... 98 Smg6 ...... 864C, 865A Ndg ...... 835A R...... 162C smo ...... 199A, 682A nej ...... 828C r2d2 ...... 871A sna ...... 810C, 843C, 846C Nhe2 ...... 45 Rab11 ...... 194B, 622A snf ...... 874A ninaE ...... 236B, 651C Rab5 ...... 195C SNF1A ...... 169A, 768C nmd ...... 597C, 604A Rab8 ...... 195C Socs36E ...... 213C Nmnat ...... 698B Rac1 ...... 83, 166A soti ...... 274A nompA ...... 718A Ras85D ...... 48, 232A, 432C, 764B sp ...... 958A nompC ...... 718A raw ...... 190A Spargel ...... 131 nopo ...... 60 Rbf ...... 110, 243C, 263B, 305B spas ...... 716B, 729C Nos ...... 773B Rbf2 ...... 263B spdo ...... 224B nos ...... 15, 868A, 879C rdgC ...... 236B spi ...... 170B, 244A Np ...... 556A ref(2)P ...... 776B, 782B spir ...... 567C Nplp1 ...... 707B Rel ...... 124 spn-A ...... 76 nub ...... 719B, 832A Rep ...... 224B spn-E ...... 576C numb ...... 160A repo ...... 19 Spn1 ...... 621C Or83b ...... 628A resilin ...... 658A sprd ...... 958A orb2 ...... 661A rhea ...... 91, 175A sqh ...... 91, 169A, 176B, 217A os ...... 46, 902B rho ...... 243C, 817A Src42A ...... 89 osk ...... 15, 209B, 868A, 869B Rho1 ...... 91, 162C srp ...... 892A otk ...... 151 RhoGEF2 ...... 2 Stat92E ...... 13, 46, 101, 119, 213C, p38b ...... 119 rin ...... 325A ...... 293B, 559A, 880A, 891C, 902B p53 ...... 283A rk ...... 658A stau ...... 209B, 869B pain ...... 682A rl...... 232A, 246C, 764B, 809B, 933C stck ...... 177C Pak ...... 166A, 893B rno ...... 243C stnB ...... 705C Pak3 ...... 729C robo ...... 692B Strn-Mlck ...... 958A par-1 ...... 706A robo3 ...... 692B Su(H) ...... 481A, 737B, 817A, 892A par-6 ...... 583A rok ...... 176B su(Hw) ...... 78, 377B, 862A Patr-1 ...... 16 roX1 ...... 82, 916A Su(var)205 ...... 30, 76, 354C, 357C, 363C, pav ...... 2 Rpd3 ...... 650B ...... 366C, 385A, 650B, 887B Pax ...... 91 Rpn12R ...... 598A Su(var)3-9 ...... 363C, 366C pbl ...... 2 rpr ...... 282C, 296B, 297C, 379A Su(z)2...... 393C pburs ...... 658A Rpt3R ...... 598A suo ...... 350B Pc ...... 363C, 389B, 390C Rpt4R ...... 598A SuUR ...... 63 pdm2 ...... 719B, 832A Rpt6R ...... 598A sv ...... 481A, 824B pds5 ...... 262A rumi ...... 154, 230B svp ...... 827B peb ...... 92 rump ...... 15 sxc ...... 774C per ...... 651C, 774C Saf-B ...... 396C Sxl ...... 346A, 874A, 879C pex16 ...... 445A salm ...... 592A, 827B synj ...... 67 pex2 ...... 445A Samuel ...... 601A Tao-1 ...... 7 PGRP-LC ...... 632B Sas-4 ...... 311B tau ...... 421A pho ...... 389B sav ...... 7 Tbh ...... 582C Pi3K68D ...... 149 sax ...... 708C Tbp ...... 427A pie ...... 271A Sb ...... 556A Tdc2 ...... 582C Pink1 ...... 436A sc ...... 849C Tel ...... 387C piwi ...... 9, 10 sca ...... 224B th ...... 198C, 282C pk ...... 51, 159C scny ...... 153, 635B thoc5 ...... 603C Pka-C1 ...... 198C scrib ...... 400A tilB ...... 683B Pkd2 ...... 610A sda ...... 449B tim ...... 651C ple ...... 666C sec15 ...... 622A Tis11 ...... 860B pnt ..... 141, 247A, 481A, 725B, 737B, 760A sec31 ...... 697A tko ...... 459C Pof ...... 366C sec6 ...... 148 tkv ...... 148, 704B, 707B, 708C, 758B polo ...... 2, 100 sec8 ...... 148 Tl ...... 246C, 613A, 620B, 772A Poxn ...... 474C sei ...... 49, 791B tlk ...... 616A ppk ...... 673A seq ...... 216C, 693C tll ...... 809B pps ...... 874A Ser ...... 225C, 737B tna ...... 391A Pros6T...... 598A sgg ...... 155, 341B tomb ...... 814A 116

FlyBase Genetic Index to Abstracts

Top2 ...... 350B twi ...... 557B, 810C, 817A, 933C W ...... 252C, 282C topi ...... 814A Uba1 ...... 432C wg ...... 19, 151, 155, 163A, 341B, 760A tor ...... 246C, 764B Ube3a ...... 404B, 405C wit ...... 191B, 707B, 708C Tor ...... 3, 169A, 772A unc-104 ...... 88 Wnk ...... 163A tra ...... 101 Upf1 ...... 864C, 865A Wnt4 ...... 151 Tre ...... 690C, 773B Upf2 ...... 863B, 864C, 865A wts ...... 7 trh ...... 546C Upf3 ...... 865A wupA ...... 807C trio ...... 166A, 693C ush ...... 892A Xrp1 ...... 863B Trl ...... 888C usp ...... 314B yki ...... 7, 239B, 886A trol ...... 169A vas ...... 209B, 868A yrt ...... 171C TrpA1 ...... 682A vg ...... 468C Zasp52 ...... 183C tsr ...... 174C Vha100-1 ...... 787A zfh1 ...... 902B tsu ...... 232A vis...... 814A Zfrp8 ...... 907A tt ...... 958A vkg ...... 95 zip ...... 217A, 252C ttk ...... 577A vn ...... 244A, 760A, 817A Zpr1 ...... 548B tud ...... 570C vnd ...... 817A Zw ...... 276C tum ...... 2, 166A Vps16A ...... 420C tup ...... 558C vvl ...... 910A

117

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