Petersberg13-18 SEPTEMBER 2014 th 30 SYMPOSIUM OF THE COLLEGIUM INTERNATIONALE ALLERGOLOGICUM WWW.CIAWEB.ORG Preliminary Program

Allergies: Current challenges and solutions

* * “Fc-epsilon binding to FcεRI (in tan) from the mast cell perspective”. The Fc-portion of IgE bends via conformational changes in order to bind, which improves mainly free entropy and confers a very slow rate of IgE dissociation from the receptor. Done with VMD1 based on the 2Y7Q coordinates done by HOLDOM et al. 1Humphrey, W., Dalke, A. and Schulten, K., “VMD - Visual Molecular Dynamics”, J. Molec. Graphics, 1996, vol. 14, pp. 33-38. CIA-0112-044 Petersberg13-18 SEPTEMBER 2014 GERMANY

th WWW.CIAWEB.ORG 30 SYMPOSIUM OF THE COLLEGIUM INTERNATIONALE ALLERGOLOGICUM

2012-2014 Dear Colleagues, COLLEGIUM COUNCIL It is our great pleasure to invite you to participate in the 30th Symposium of the Collegium President Internationale Allergologicum entitled Allergies: Current challenges and solutions from 13-18 Stephen J. Galli September 2014 in Petersberg, Germany. The purpose of this meeting, like all meetings of the Collegium, is to bring basic and translational Past President scientists, clinical immunologists, and allergists together to foster interdisciplinary approaches to Gianni Marone understand, treat, and, ultimately, cure immunological disorders. Vice President/ As in previous meetings, the majority of the scientific program will be given over to free Past Secretary General communications that will be presented either orally or as poster discussions. The Collegium’s Stephen Holgate unique organizational structure and membership guidelines ensure that the science presented at the biennial symposia of the Collegium is not only important, but includes many late-breaking and Secretary General in many cases unpublished developments. Bruce S. Bochner We believe that the venue selected by the Council of the Collegium for its 30th meeting will Council Members accommodate scientists and accompanying persons in the tradition and style that have Dean Befus characterized past meetings of the Collegium. Heidrun Behrendt Heimo Breiteneder Petersberg is a prominent hill with a height of 331 meters (1,086 ft) in the Siebengebirge Stephen Durham mountain range near , Germany. It overlooks the cities of Königswinter on the right bank Kenji Izuhara of the River, and Bonn on the opposite side. The Siebengebirge (“seven hills” in German) Hans-Uwe Simon is a German upland range to the East of the Rhine, southeast of Bonn, consisting of more than Marianne van Hage 40 hills. It is of volcanic origin and much of the territory covered by the Siebengebirge belongs Peter Weller to the Naturpark Siebengebirge, which is under environmental protection. It is a popular tourist destination for hiking, because of its natural beauty. Symposium Organizers Marcus Maurer On behalf of the Collegium Council Members, we look forward to welcoming you to Petersberg in Heidrun Behrendt 2014, and we hope that we can rely upon your support in what promises to be a combination of excellent science in a convivial atmosphere. Local Organizing Committee Thomas Bieber Yours sincerely, Johannes Ring

Stephen J. Galli Marcus Maurer Heidrun Behrendt President Symposium Organizer Symposium Organizer

Executive Secretariat 555 East Wells Street Suite 1100 Milwaukee, WI 53202-3823 USA

Tel. +1 414 918 3018 Fax. +1 414 276 3349 [email protected] www.ciaweb.org

Preliminary Program • Allergies: Current challenges and solutions • Petersberg, Germany 1 General Information The 30th Symposium of the Collegium will be held in Petersberg, Social Events Germany. Petersberg overlooks the cities of Königswinter on the All Social Events are included in the registration fee for both right bank of the Rhine River, and Bonn on the opposite side. delegates and accompanying persons. The Siebengebirge (“seven hills” in German) is a German upland range to the East of the Rhine, southeast of Bonn, consisting of Welcome Reception more than 40 hills. It is a popular tourist destination for hiking, Saturday, 13 September 2014, 18:30 – 21:30 because of its natural beauty. The Welcome Reception will be held on the terrace of the Steigenberger Hotel overlooking the Rhine Valley with Currency refreshments and an assortment of hors d’oeuvres. The currency used in Germany is the Euro. There are ATMs, or Boat Ride Bancomats, widely available for cash withdrawal. Credit cards Tuesday, 16 September 2014, 11:00 – 19:00 are also accepted at most hotels, restaurants and shops. Following in the tradition of past Collegium meetings, a boat ride will take place on the fourth day of the meeting. Participants Electricity will enjoy a leisurely cruise with fantastic views of the Rhine. The electrical current in Germany is 220 volts. The European Plug The Boat will dock in the town of Leutesdorf and attendees will with round prongs is acceptable. enjoy a wine tasting at Winery Mohr. The Winery was founded in 1875 and has been operated by the family for four generations. Hotel Shuttle Participants will return via boat and will be dropped off at the Shuttle transportation will be provided between the hotel Informal Dinner. venues. The shuttle will pick up at the Steigenberger Hotel and the Maritim Hotel. Attendees staying at the Rheinhotel Loreley Informal Dinner will catch the shuttle at the Maritim Hotel located nearby. The Tuesday, 16 September 2014, 19:00 – 22:00 shuttle will take approximately 20 minutes one way. After the boat ride, the Informal Dinner will take place at the Rheinhotel Dreesen located along the Rhine River. The evening Language will include musical entertainment. The official language of the 30th Symposium is English. Gala Dinner Wednesday, 17 September 2014, 19:30 – 23:00 Lunches An elegant dinner will be held on the last evening of the Buffet-style lunches will be served in the Steigenberger Symposium at the Steigenberger Hotel in the Rotunde room. Live Hotel following the Oral Abstract Sessions on 14, 15, and 17 classical music will be provided at the opening of the evening. September. Lunch is included in the registration fee for both delegates and accompanying persons. A box lunch will be available for delegates before the boat ride on 16 September.

Bonn, Germany

2 30th Symposium of the Collegium Internationale Allergologicum • 13 -­ 18 September 2014 General Information Time Zone Venue Germany is on Central European Time Zone, which is two hours The scientific program of the 30th Symposium will take place ahead of Greenwich Mean Time (GMT) during the summer. at the Steigenberger Hotel on 14, 15, 17 and 18 September. The poster sessions on 14, 15 and 17 September, the Relaxing Tipping Lecture on 15 September and the Oral Abstract Session on 16 This is generally done at the table with the waiter or waitress September will take place at the Maritim Hotel. who served you. Depending on the service you received, you should tip the normal 10 percent or so. Of course, if the service Weather was poor, you don’t have to tip at all. It is wise to always check The average temperature in September is between 19°C/66°F about credit card payment before you order. For a taxi, tipping and 10°C/50°F. isn’t necessary, but most round-up the fare to the nearest Euro. Travel Arrangements and Airport Transfers You can fly directly to the /Bonn Airport from most major European cities. The Collegium will arrange transportation to/from the airport in Cologne/Bonn to the hotels in Königswinter. Transportation will also be provided between the meeting venue and the hotels. The shuttle bus is included in the registration fee. Attendees can make their own arrangements to travel directly from the Frankfurt Airport to Petersberg, but electing this option will incur additional expense and is likely to be less convenient than using the transfer service from the Cologne/Bonn Airport that will be provided as part of the registration fee. Frankfurt Airport transportation details can be found online at www. ciaweb.org/2014-symposium/general-information. It is recommended that participants wishing to attend the Welcome Reception on the evening of 13 September arrive no later than 16:00 that same day to allow for airport transfer times.

Cologne, Germany

Preliminary Program • Allergies: Current challenges and solutions • Petersberg, Germany 3 2014 Program-at-a-Glance

7:00 8:00 9:00 10:00 11:00 12:00 13:00 14:00

Registration Open Saturday Saturday 13 September

Registration Open at Steigenberger Hotel

Speaker Ready Room Open

Coffee Sunday Sunday Oral Abstracts Break Oral Abstracts Lunch 14 September CIA Council Lunch

Registration Open at Steigenberger Hotel

Speaker Ready Room Open Monday Monday

15 September Coffee Life in Science Oral Abstracts Break Oral Abstracts Lunch

Registration Open

Speaker Ready Room Open Tuesday Tuesday Carl Prausnitz 16 September Life in Science Oral Abstracts Lunch and Boat Ride Lecture

Registration Open at Steigenberger Hotel

Speaker Ready Room Open

Wednesday Wednesday Paul Kallos 17 September

Life in Science Oral Abstracts Oral Abstracts CIA Lunch

Break Lecture Coffee Coffee Meeting Business

Registration Open at Steigenberger Hotel

Speaker Preview Room Open Thursday Thursday

18 September CIA Council Life in Science Oral Abstracts Oral Abstract

Meeting Break Coffee Coffee

4 30th Symposium of the Collegium Internationale Allegologicum • 13 -­ 18 September 2014 2014 Program-at-a-Glance

15:00 16:00 17:00 18:00 19:00 20:00 21:00 22:00

Registration Open at Steigenberger Hotel

Welcome Reception at Steigenberger Hotel

Registration Open at Maritim Hotel

Poster Session

Registration Open at Maritim Hotel

Relaxing Lecture Poster Session

Informal Dinner

Registration Open at Maritim Hotel

Poster Sessions Gala Dinner

*Schedule subject to change.

Preliminary Program • Allergies: Current challenges and solutions • Petersberg, Germany 5 Call for Abstracts

Abstracts can be submitted in the following categories: Deadline for Abstract Category 1: Genetic and environmental factors in allergic disorders Submission • Genetics of allergic disorders 19 March 2014 • Environmental factors in immune disorders • Epidemiology: risk and protective factors in allergy Late Breaking Abstract Category 2: Dendritic cells, mast cells, monocytes, neutrophils, eosinophils and Submission Deadline basophils 20 May 2014 • Dendritic cells Submit Abstracts Online at: • Monocytes/macrophages https://cia.execinc.com/edibo/ • Mast cells and basophils Abstracts14 • Eosinophils and neutrophils Word Limit: 350 words Category 3: Lymphocytes and mediators of immunoregulation The Collegium Internationale • Cytokines Allergologicum invites members • Chemokines and non-members to submit • T-Cells and regulatory T-cells abstracts for review for poster or • NK and iNKT cells oral presentation. • Immunoregulation The following guidelines address • Adjuvants key factors that the Collegium Category 4: Food and drug allergies and gastrointestinal disorders Internationale Allergologicum Organizing Committee considers Category 5: Asthma, rhinitis and atopic dermatitis when reviewing abstracts. Category 6: Urticaria, angioedema and anaphylaxis Attention to these details will assist Category 7: Allergens and diagnosis of allergy the Committee in making their • Allergens decision. • Triggers of allergy 1. Abstracts should contain a • Biomarkers of allergy: prognosis, severity and treatment efficacy concise statement of the • Diagnostic methodologies problem under investigation; describe experimental methods Category 8: Pathophysiology of allergic disorders and inflammation used; contain specific findings • Animal models of allergy and data (promises such as • Mediators of inflammation “the results to be completed” • Immunoglobulins: roles, receptors, regulation are not appropriate); and • Pathophysiology of the allergic response contain conclusions based on • Inflammation: acute/chronic the data presented (statistical • Nerves and inflammation analyses should be used when Category 9: Treatment of immune disorders appropriate to support the • Immunomodulation: strategies for prevention and treatment conclusions). • Allergic diseases 2. Define all concepts and • Autoimmune diseases abbreviations at first use. Do not • Immunodeficiencies use abbreviations in the title of • Experimental therapeutics the abstract. Category 10: Allergen specific immunotherapy 3. Previously published abstracts • SLIT will NOT be considered. • SCIT 4. All abstract presenters will • Novel therapies be required to register for the symposium, and pay all Category 11: Networks registration and travel costs. 5. Abstract submissions can only be made by Collegium Internationale Allergologicum members, candidates or by non- members whose submission is sponsored by a member.

6 30th Symposium of the Collegium Internationale Allergologicum • 13 -­ 18 September 2014 Scientific Program CME Accreditation Poster Sessions Approval of the scientific program for continuing medical Poster Sessions will take place from 17:00 – 19:00 on 14, 15, education (CME) credits will be applied for with the European and 17 September at the Maritim Hotel. An assortment of wine, Accreditation Council for Continuing Medical Education cheese and other refreshments will be served. Poster presenters (EACCME). The EACCME is an institution of the European Union will stand next to their posters during assigned sessions and be of Medical Specialists (UEMS). EACCME credits are recognized by available for questions and discussion. the American Medical Association (AMA). More information regarding CME will be available closer to the “Life in Science” Breakfast Discussions These sessions are geared towards young scientists at the dates of the meeting. beginning of their career. Sessions will be in an informal session Oral Abstract Sessions where an eminent scientists will share with young investigators Highly scored abstracts will be placed in Oral Abstract Sessions some of what they have experienced and learned in their “Life in on 14, 15, 16, 17, and 18 September. Oral Abstract Sessions on Science.” Space is limited; sign up online during the registration 14, 15, 17 and 18 September will take place at the Steigenberger process. Hotel and oral abstracts on 16 September will take place at the Maritim Hotel.

Alain L. de Weck Travel Grants Travel Grant Application Deadline: Please send completed applications to: 19 March 2014 Kate Filipiak Award Executive Director • Grants will be awarded in order to supplement travel and hotel Collegium Internationale Allergologicum costs 555 East Wells Street, Suite 1100 Milwaukee, WI 53202 • Registration fee will be waived USA Specifications Fax: +1 414 276 3349 • Preference will be given to young scientists in the early stages Email: [email protected] of their career All applications will be reviewed by the Collegium Council. • Symposium abstract must be selected for poster or oral presentation for the upcoming symposium • Grant is only awarded once per individual Application • Candidates must provide: ––A short letter of application, which includes the reasons for applying ––State his/her age ––A copy of his/her abstract ––Letter of recommendation from a colleague who is a current member of the Collegium ––Curriculum Vitae

Preliminary Program • Allergies: Current challenges and solutions • Petersberg, Germany 7 Invited Speakers Relaxing Lecture Paul Kallos Lecture Prof. Dr. Wilhelm Barthlott Bruce Beutler, MD The secret of sacred lotus: Learning from biological surfaces Genetic analysis of immune responses Monday, 15 September 2014 Wednesday, 17 September 2014 16:00 – 17:00 12:00 – 13:00 Wilhelm Barthlott is a German botanist and Bruce Beutler is a Regental Professor and bionics expert. He studied biology at the Director of the Center for the Genetics of Host University of Heidelberg, Germany. Barthlott’s Defense at UT Southwestern Medical Center in areas of specialization are systematics and Dallas, Texas. He received his medical training biodiversity research, with the main focus at the University of Chicago, graduating in 1981. devoted to tropical ecosystems and the global As a postdoctoral fellow at The Rockefeller distribution of biodiversity. He is one of the pioneers in the field University (1983-1986), he isolated mouse tumor necrosis of biological and technical interfaces. Based on his systematic factor (TNF) and discovered its importance as a mediator of research on scanning electron microscopy of plant surfaces, he inflammation. Subsequently, at UT Southwestern, he analyzed developed self-cleaning (lotus effect) technical surfaces and, mammalian responses to bacterial lipopolysaccharide. This in recent years, surfaces which permanently retain air under work culminated in the identification of Toll-like receptors as key water. This led to a paradigm shift in particular areas of materials sensors of the innate immune system, used to detect infection. science and facilitated the development of superhydrophobic In further studies, Beutler employed a forward genetic strategy biomimetic surfaces. This technology has successfully been to elucidate many aspects of mammalian immunity. launched on the market under the trademark Lotus-Effect®. He has received numerous awards for his work including the Barthlott has been honored with various awards and prizes, e. g. Balzan Prize (2007), the Albany Medical Center Prize (2009), the German Environment Prize (Deutscher Umweltpreis). He is the Shaw Prize (2011), and election to both the US National a member of the Academy of Sciences and Literature of Mainz, Academy of Sciences and the Institute of Medicine (2008). In the North Rhine-Westphalia Academy of Sciences and Arts, 2011, he shared the Nobel Prize in Physiology or Medicine for the German Academy of Sciences Leopoldina, and is a Foreign “discoveries concerning the activation of innate immunity.” Member of the Linnean Society of London. Carl Prausnitz Lecture Stephen J. Galli, MD Contributions of mast cells and IgE to innate and acquired resistance to venoms: Is this the “good side” of allergy? Tuesday, 16 September 2014 9:30 – 10:30 Stephen J. Galli, MD, is chair of the Department of Pathology, the Mary Hewitt Loveless, MD Professor, and a professor of pathology and of microbiology and immunology at Stanford. Steve investigates the development and function of mast cells and basophils and has developed new animal models for analyzing the roles of these cells in health and disease. This work has elucidated diverse functions of mast cells in models of allergic diseases and other disorders, and also has shown that mast cells can contribute to innate and, along with IgE antibodies, adaptive immune responses that increase host resistance to animal venoms. Steve was president of the American Society for Investigative Pathology (2005-2006) and has been elected to the Pluto Club (Association of University Pathologists), the Collegium Internationale Allergologicum (serving as president from 2010- 2014), the American Society for Clinical Investigation, the Association of American Physicians, and the Institute of Medicine of the U.S. National Academies, and is a foreign member of the Accademia Nazionale dei Lincei in Rome.

8 30th Symposium of the Collegium Internationale Allergologicum • 13 -­ 18 September 2014 Registration

To register for the meeting, please complete the registration Registration Cancellation Policy form at the end of this program. Online registration is also By 20 May 2014: available at www.ciaweb.org. Payments must be made in Euros Cancellations will be reimbursed in full by wire transfer or by credit card. Between 21 May and 15 July 2014: The registration desk will be located in the lobby of the Cancellations will be charged 50% penalty Steigenberger Hotel on the evening of Saturday, 13 September After 15 July 2014: 2014 from 14:00 – 19:00, and each day of the meeting Cancellations will not be reimbursed thereafter. Registration will also be available at the Maritim Hotel during the poster sessions. Registration Fees Special package rates have been arranged to include registration fees, meals, airport transfers and social activities. Paid on or before 20 May 2014 • Delegate: €875 • Accompanying Person: €525 • Accompanying Child: €200 Paid between 21 May and 31 July 2014 • Delegate: €925 • Accompanying Person: €575 • Accompanying Child: €200 Paid on or after 1 August 2014 or onsite • Delegate: €975 • Accompanying Person: €625 • Accompanying Child: €200 The registration fee for delegates includes: • Airport Transfer on Arrival ––From Cologne/Bonn Airport to the hotels • Airport Transfer on Departure ––From the hotels to the Cologne/Bonn Airport • Oral Abstract Sessions • Poster Sessions • Coffee Breaks • Lunches • Social Events (Welcome Reception, Boat Ride, Informal Dinner, Gala Dinner) • Hotel Shuttle Transportation The registration fee for accompanying persons includes: • Airport Transfer on Arrival ––From Cologne/Bonn Airport to the hotels • Airport Transfer on Departure ––From the hotels to the Cologne/Bonn Airport • Lunches • Social Events (Welcome Reception, Boat Ride, Informal Dinner, Gala Dinner) • Hotel Shuttle Transportation

Preliminary Program • Allergies: Current challenges and solutions • Petersberg, Germany 9 Hotel Accommodations

Hotel Reservation Deadline The Maritim Hotel 31 July 2014 The Maritim Hotel Koenigswinter is located right on the Rhine Promenade on the idyllic Wine City, just a few minutes on foot from the pedestrian zone and the valley station of the Drachenfels rail. The Bonn inner city, the Cologne Bonn airport and the Cologne trade fair centre are just a few minutes away via the motorway. Those who wish may also take the Rhine ferry right in front of the hotel to Bad Godesberg on the other bank. http://www.maritim.com/en/hotels/germany/hotel- koenigswinter Room Types and Pricing 12-13 September Single room €122 Double room €150 14-19 September Single room €137 The Collegium has secured room blocks at the Steigenberger Double room €165 Grandhotel Petersberg, the Maritim Hotel and the Rheinhotel All prices are per room, per night. Buffet breakfast, VAT and taxes Loreley. The Maritim and Rheinhotel Loreley are located in included. the town of Königswinter and transportation will be provided between the Steigenberger Hotel and Maritim Hotel. Rheinhotel Loreley The three-star-hotel Rheinhotel Loreley is a beautiful old Hotel reservations can be made by using the registration form at traditional hotel situated directly at the Rhine. The hotel offers the end of the program or online at www.ciaweb.org. Payments 49 comfortable and well-kept rooms with modern amenities and must be made in Euros, by credit card. a rich breakfast with various delicious choices. Standard single Accommodation Options and double rooms provide a shower/WC, cable TV, landline Steigenberger Grandhotel Petersberg telephone as well as a desk. Moreover, the hotel offers safes, The Steigenberger Grandhotel Petersberg sits on the mountain internet access and laundry services. All rooms can be accessed of the same name in the Siebengebirge. The sophisticated with an elevator. Meals can be taken in the elegant restaurant style of the building continues in the interior of the spacious offering traditional, regional and seasonal dishes. Also, the Rhine and comfortable rooms and suites. Mountain bikers and racing terrace is a perfect spot for a glass of excellent regional wine or cyclists can find varied challenges in the mountain roads and a sundowner along with a fantastic view on the river. You would on the paths along the banks of the Rhine. Hikers and strollers like to get a first impression yourself? A short hotel video can be will find any number of small tours and tours of medium length found here: http://www.hotelloreley.de/hotelvideo.html whereby the Rheinsteig hiking trail is among the most beautiful. Room Types and Pricing http://en.steigenberger.com/Koenigswinter-Bonn/Steigenberger- Single room €120 Grandhotel-Petersberg Double Room €144 Room Types and Pricing All prices are per room, per night. Buffet breakfast, VAT and taxes Economy Single €125 included. Standard Single €155 Room reservations will be based on availability after 31 July 2014. Standard Double room (one person) €175 Standard Double room (two people) €195 Accommodation Cancellation Policy Standard Double Rhine View room (one person) €195 By 30 June 2014 Standard Double Rhine View room (two people) €215 Cancellations will be reimbursed in full Deluxe Double room (one person) €205 Between 1 July and 31 July 2014 Deluxe Double room (two people) €225 Cancellations will be charged at 50% of the entire stay Deluxe Rhine View room (one person) €225 After 1 August 2014 Deluxe Rhine View room (two people) €245 Cancellations will not be reimbursed. Suite (one person) €370 No shows, early departures and postponed arrivals will not be Suite (two people) €390 reimbursed. All prices are per room, per night. Buffet breakfast, VAT and taxes included.

10 30th Symposium of the Collegium Internationale Allergologicum • 13 -­ 18 September 2014 Registration and Accommodation Form Early Registration Deadline: 20 May 2014 ~ Late Registration Deadline: 31 July 2014 Online Registration is available at:www.ciaweb.org

Prefix First Name Last Name Designation

Institution

Address

Address

City State Zip/Postal Code Country

Phone Fax Email

CIA Member Non-member (must be sponsored by a CIA Member)

Sponsored by REGISTRATION FEE Paid on or before 20 May 2014 Delegate: €875 Accompanying Person: €525 Accompanying Child: €200 Paid between 21 May and 31 July 2014 Delegate: €925 Accompanying Person: €575 Accompanying Child: €200 Paid on or after 1 August 2014 or onsite Delegate: €975 Accompanying Person: €625 Accompanying Child: €200

Name of Accompany Person (as it will appear on his/her badge) Total Registration Fee: € (amount from above) Life in Science Breakfast (geared towards young scientists) Monday, 15 September (Donata Vercelli) Wednesday, 17 September (Mübeccel Akdis and Cezmi Akdis) Tuesday, 16 September (Bruce S. Bochner) Thursday, 18 September (Stephen J. Galli) HOTEL ACCOMMODATIONS

Arrival Date Departure Date Please select your preferred hotel. Rooms will be allocated on a first come, first serve basis. Steigenberger Grand Hotel Petersberg FRIDAY, 12 SEPTEMBER 2014 Economy Single...... €125 Deluxe Double room (two people)...... €225 Standard Single...... €155 Standard Single...... €155 Deluxe Rhine View room (one person)...... €225 Standard Double room (one person)...... €175 Standard Double room (one person)...... €175 Deluxe Rhine View room (two people)...... €245 Standard Double room (two people)...... €195 Standard Double room (two people)...... €195 Suite (one person)...... €370 Deluxe Double room (one person)...... €205 Standard Double Rhine View room Suite (two people)...... €390 Deluxe Double room (two people)...... €225 (one person)...... €195 TUESDAY, 16 SEPTEMBER 2014 Deluxe Rhine View room (one person)...... €225 Standard Double Rhine View room Economy Single...... €125 Deluxe Rhine View room (two people)...... €245 (two people)...... €215 Standard Single...... €155 SATURDAY, 13 SEPTEMBER 2014 Deluxe Double room (one person)...... €205 Standard Double room (one person)...... €175 Economy Single...... €125 Deluxe Double room (two people)...... €225 Standard Double room (two people)...... €195 Standard Single...... €155 Deluxe Rhine View room (one person)...... €225 Standard Double Rhine View room Standard Double room (one person)...... €175 Deluxe Rhine View room (two people)...... €245 (one person)...... €195 Standard Double room (two people)...... €195 Suite (one person)...... €370 Standard Double Rhine View room Standard Double Rhine View room Suite (two people)...... €390 (two people)...... €215 (one person)...... €195 MONDAY, 15 SEPTEMBER 2014 Deluxe Double room (one person)...... €205 Standard Double Rhine View room Economy Single...... €125 Deluxe Double room (two people)...... €225 (two people)...... €215 Standard Single...... €155 Deluxe Rhine View room (one person)...... €225 Deluxe Double room (one person)...... €205 Standard Double room (one person)...... €175 Deluxe Rhine View room (two people)...... €245 Deluxe Double room (two people)...... €225 Standard Double room (two people)...... €195 Suite (one person)...... €370 Deluxe Rhine View room (one person)...... €225 Standard Double Rhine View room Suite (two people)...... €390 Deluxe Rhine View room (two people)...... €245 (one person)...... €195 WEDNESDAY, 17 SEPTEMBER 2014 Suite (one person)...... €370 Standard Double Rhine View room Economy Single...... €125 Suite (two people)...... €390 (two people)...... €215 Standard Single...... €155 SUNDAY, 14 SEPTEMBER 2014 Deluxe Double room (one person)...... €205 Standard Double room (onecontinued person)...... on next€175 page Preliminary Program • Allergies: Current challenges and solutions • Petersberg, Germany 11 Steigenberger Grand Hotel Petersberg (cont.) FRIDAY, 12 SEPTEMBER 2014 Rheinhotel Lorley Standard Double room (two people)...... €195 Single room...... €122 FRIDAY, 12 SEPTEMBER 2014 Standard Double Rhine View room (one person)... Double room...... €150 Single room...... €120 €195 SATURDAY, 13 SEPTEMBER 2014 Double room...... €144 Standard Double Rhine View room (two people).. Single room...... €122 SATURDAY, 13 SEPTEMBER 2014 €215 Double room...... €150 Single room...... €120 Deluxe Double room (one person)...... €205 SUNDAY, 14 SEPTEMBER 2014 Double room...... €144 Deluxe Double room (two people)...... €225 Single room...... €137 SUNDAY, 14 SEPTEMBER 2014 Deluxe Rhine View room (one person)...... €225 Double room...... €165 Single room...... €120 Deluxe Rhine View room (two people)...... €245 MONDAY, 15 SEPTEMBER 2014 Double room...... €144 Suite (one person)...... €370 Single room...... €137 MONDAY, 15 SEPTEMBER 2014 Suite (two people)...... €390 Double room...... €165 Single room...... €120 THURSDAY, 18 SEPTEMBER 2014 TUESDAY, 16 SEPTEMBER 2014 Double room...... €144 Economy Single...... €125 Single room...... €137 TUESDAY, 16 SEPTEMBER 2014 Standard Single...... €155 Double room...... €165 Single room...... €120 Standard Double room (one person)...... €175 WEDNESDAY, 17 SEPTEMBER 2014 Double room...... €144 Standard Double room (two people)...... €195 Single room...... €137 WEDNESDAY, 17 SEPTEMBER 2014 Deluxe Double room (one person)...... €205 Double room...... €165 Single room...... €120 Deluxe Double room (two people)...... €225 THURSDAY, 18 SEPTEMBER 2014 Double room...... €144 Deluxe Rhine View room (one person)...... €225 Single room...... €137 THURSDAY, 18 SEPTEMBER 2014 Deluxe Rhine View room (two people)...... €245 Double room...... €165 Single room...... €120 FRIDAY, 19 SEPTEMBER 2014 FRIDAY, 19 SEPTEMBER 2014 Double room...... €144 Standard Single...... €155 Single room...... €137 FRIDAY, 19 SEPTEMBER 2014 Standard Double room (one person)...... €175 Double room...... €165 Single room...... €120 Standard Double room (two people)...... €195 Double room...... €144 Deluxe Double room (one person)...... €205 Deluxe Double room (two people)...... €225 All prices are per room, per night. Breakfast, taxes and service charge included. Deluxe Rhine View room (one person)...... €225 Total Accommodation Price: Deluxe Rhine View room (two people)...... €245 Maritim Hotel € (amount from above)

AIRPORT TRANSFERS from the Cologne/Bonn Airport (included in the registration rate) Number of People:

Flight Arrival Date Flight Arrival Time Airline and Flight Number

Flight Departure Date Flight Departure Time Airline and Flight Number If you have not yet booked your flight to the Cologne/Bonn Airport, please send your information to Kate Filipiak ([email protected]) by 15 August 2014 in order to arrange your transfer.

OTHER REQUIRMENTS Please indicate if you have a disability for which you will require special accommodations, or inform of any dietary requirements if applicable. (For example: vegetarian, no fish, no meat, gluten free, no pork, etc.)

TOTAL REGISTRATION AND HOTEL FEES: € PAYMENT Credit Card Type: VISA MasterCard

Credit Card Number Expiration Date

Signature

DISCLAIMER All prices are listed in Euros. CIA processes all payments in USD, ACCOMMODATION CANCELLATION POLICY By 30 June 2014: Cancellations therefore, credit card statements may not show the exact amount, depending will be reimbursed in full. Between 1 July and 31 July 2014: Cancellations will on the exchange rate. be charged at 50% of the entire stay. After 1 August 2014: Cancellations will not be reimbursed. REGISTRATION CANCELLATION POLICY By 20 May 2014: Cancellations will be reimbursed in full. Between 21 May and 15 July 2014: Cancellations will be charged 50% penalty. After 15 July 2014: Cancellations will not be reimbursed. No shows, early departures and postponed arrivals will not be reimbursed.

12 30th Symposium of the Collegium Internationale Allegologicum • 13 -­ 18 September 2014 Gold Supporter

Silver Supporter

Bronze Supporters

Alain L. de Weck Travel Grant Supporter

Collegium Internationale Allergologicum 555 East Wells Street, Suite 1100 • Milwaukee, WI 53202 USA Phone: +1 414 918 3018 • Fax: +1 414 276 3349 Email: [email protected] • www.ciaweb.org Collegium Internationale Allergologicum 555 East Wells Street, Suite 1100 Milwaukee, WI 53202 USA