SNAI2 Antibody Cat. No.: 27-822

SNAI2 Antibody

Antibody used in WB on Transfected 293T at 0.2-1 ug/ml. Antibody used in IHC on Human Testis.

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region IMMUNOGEN: of human SNAI2.

TESTED APPLICATIONS: ELISA, WB

SNAI2 antibody can be used for detection of SNAI2 by ELISA at 1:312500. SNAI2 antibody APPLICATIONS: can be used for detection of SNAI2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

POSITIVE CONTROL: 1) Cat. No. 1219 - MCF7 Cell Lysate

PREDICTED MOLECULAR 30 kDa WEIGHT:

September 24, 2021 1 https://www.prosci-inc.com/snai2-antibody-27-822.html Properties

PURIFICATION: Antibody is purified by peptide affinity chromatography method.

CLONALITY: Polyclonal

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% BUFFER: sucrose.

CONCENTRATION: batch dependent

For short periods of storage (days) store at 4˚C. For longer periods of storage, store SNAI2 STORAGE CONDITIONS: antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Additional Info

OFFICIAL SYMBOL: SNAI2

ALTERNATE NAMES: SNAI2, MGC10182, SLUG, SLUGH1, WS2D, SNAIL2

ACCESSION NO.: NP_003059

PROTEIN GI NO.: 11276067

GENE ID: 6591

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

SNAI2 is a member of the Snail family of C2H2-type factors. The protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial- mesenchymal transitions and has antiapoptotic activity. Mutations in this may be associated with sporatic cases of neural tube defects. This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a BACKGROUND: transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

REFERENCES: 1) Mittal, M.K., (2008) Biochem. Biophys. Res. Commun. 372 (1), 30-34.

ANTIBODIES FOR RESEARCH USE ONLY.

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