JOURNAL OF VIROLOGY Volume 59 August 1986 No. 2

ANIMAL Further Characterization of the Vesicular Stomatitis Temperature-Sensitive 045 Mutant: Intracellular Conversion of the Glycoprotein to a Soluble Form. Steve S.-L. Chen and Alice S. Huang...... 210-215 DNA Sequence of the Gene for Pseudorabies Virus gp5O, a Glycoprotein without N-Linked Glycosylation. Erik A. Petrovskis, James G. Timmins, Marty A. Armentrout, Carmine C. Marchioli, Robert J. Yancey, Jr., and Leonard E. Post ...... 216-223 Replication and Resolution of Cloned Poxvirus Telomeres In Vivo Generates Linear Minichromosomes with Intact Viral Hairpin Termini. A. M. DeLange, M. Reddy, D. Scraba, C. Upton, and G. McFadden ...... 249-259 Evolutionary Changes of Transcriptional Control Region in a Minute-Plaque Viable Deletion Mutant of BK Virus. Sumie Watanabe and Kunito Yoshiike ...... 260-266 Molecular Basis for Interference of Defective Interfering Particles of Pseudorabies Virus with Replication of Standard Virus. Carol Ann Wu, Linda Harper, and Tamar Ben-Porat ...... 308-317 cis Functions Involved in Replication and Cleavage-Encapsidation of Pseudorabies Virus. Carol Ann Wu, Linda Harper, and Tamar Ben-Porat ...... 318-327 Analysis of Retroviral pol Gene Products with Antisera Raised against Fusion Proteins Produced in Escherichia coli. Naoko Tanese, Monica J. Roth, and Stephen P. Goff ...... 328-340 In Vivo Transformation of Human Skin with Human Papillomavirus Type II from Condylomata Acuminata. John W. Kreider, Mary K. Howett, Nancy L. Lill, Gerald L. Bartlett, Richard J. Zaino, Thomas V. Sedlacek, and Rodrigue Mortel ...... 369-376 Measurement of the Mutation Rates of Animal Viruses: A. Virus and Type 1. Jeffrey D. Parvin, Anne Moscona, Wayne T. Pan, Jason M. Leider, and Peter Palese ...... 377-383 Site-Directed Mutagenesis of Polyomavirus Middle-T Antigen Sequences Encoding Tyrosine 315 and Tyrosine 250. William Markland, Ben A. Oostra, Robert Harvey, Alexander F. Markham, William H. Colledge, and Alan E. Smith 384-391 Intracellular Maturation of Virus Hemagglutinin-Neuraminidase Glyco- protein: Conformational Changes Detected with Monoclonal Antibodies. M. Neal Waxham, David C. Merz, and Jerry S. Wolinsky ...... 392-400 Molecular Characterization of Marek's Disease Herpesvirus B Antigen. R. J. Isfort, I. Sithole, H. J. Kung, and L. F. Velicer ...... 411-419 Adenovirus Type 12 ElA Protein Expressed in Escherichia coli Is Functional upon Transfer by Microinjection or Protoplast Fusion into Mammalian Cells. Bernd Krippl, Ourania Andrisani, Nicholas Jones, Heiner Westphal, Martin Rosenberg, and Blair Ferguson ...... 420-427 Monoclonal Antibody Analysis of p53 Expression in Normal and Transformed Cells. Jon W. Yewdell, Julian V. Gannon, and David P. Lane ...... 444-452 Expression of the Epstein-Barr Virus Nuclear Protein 2 in Rodent Cells. Timothy Dambaugh, Fred Wang, Kevin Hennessy, Ellen Woodland, Alan Rickinson, and Elliott Kieff...... 453-462 Continued on following page Continuedfrom preceding page

Amino-Terminal Mutation of the Vesicular Stomatitis Virus Glycoprotein Does Not Affect Its Fusion Activity. Caroline Woodgett and John K. Rose ..... 486-489 Highly Infectious Plasmids Carrying Poliovirus cDNA Are Capable of Replication in Transfected Simian Cells. Katherine M. Kean, Czeslaw Wychowski, Helena Kopecka, and Marc Girard ...... 490-493 1 Recombinants with Noninverting Genomes Frozen in Different Isomeric Arrangements Are Capable of Independent Replication. Frank J. Jenkins and Bernard Roizman ...... 494-499 Molecular and Biological Properties of BK Virus-IR, a BK Virus Variant Isolated from a Human Tumor. M. Pagnani, M. Negrini, P. Reschiglian, A. Corallini, P. G. Balboni, S. Scherneck, G. Macino, G. Milanesi, and G. Barbanti-Brodano ...... 500-505 Serological Characterization of Human Reassortant . Antoine Garbarg-Chenon, Fernand Bricout, and Jean-Claude Nicolas ...... 510-513 Sequential Detection of Different Antigens Induced by Epstein-Barr Virus and Herpes Simplex Virus in the Same Western Blot by Using Dual Antibody Probes. Jung-Chung Lin and Joseph S. Pagano ...... 522-524 Mutation in the VP-1 Gene Is Responsible for the Extended Host Range of a Monkey B-Lymphotropic Papovavirus Mutant Capable of Growing in T-Lymphoblastoid Cells. Tadahito Kanda, Akemi Furuno, and Kunito Yoshiike ...... 531-534 VIRUS-CELL INTERACTIONS The Amino-Terminal Domain of the v-fms Oncogene Product Includes a Function- al Signal Peptide That Directs Synthesis of a Transforming Glycoprotein in the Absence of Feline Leukemia Virus gag Sequences. Esther F. Wheeler, Martine F. Roussel, Annie Hampe, Mary H. Walker, Victor A. Fried, A. Thomas Look, Carl W. Rettenmier, and Charles J. Sherr ...... 224-233 Expression of Molecular Clones of v-myb in Avian and Mammalian Cells Indepen- dently of Transformation. Joseph S. Lipsick, Carlos E. Ibanez, and Marcel A. Baluda...... 267-275 Production of Acquired Syndrome-Associated Retrovirus in Human and Nonhuman Cells Transfected with an Infectious Molecular Clone. Akio Adachi, Howard E. Gendelman, Scott Koenig, Thomas Folks, Ronald Willey, Arnold Rabson, and Malcolm A. Martin ...... 284-291 Deletions in the N-Terminal Coding Region of the v-sis Gene: Determination of the Minimal Transforming Region. Monica K. Sauer, Mark Hannink, and Daniel J. Donoghue ...... 292-300

A Novel Retroviruslike Family in Mouse DNA. Ahuva Itin and Eli Keshet ..... 301-307 Structure and Transforming Function of Transduced Mutant Alleles of the Chicken c-myc Gene. Tilo Patschinsky, Hans W. Jansen, Helmut Blocker, Ronald Frank, and Klaus Bister ...... 341-353 Characterization of Rous Sarcoma Virus-Related Sequences in the Japanese Quail. Judith A. Chambers, Anita Cywinski, Pei-Jer Chen, and John M. Taylor ...... 354-362 Synthesis and Processing of Bovine Herpesvirus 1 Glycoproteins. Sylvia van Drunen Littel-van den Hurk and Lorne A. Babiuk ...... 401-410 Differential Expression of Endogenous Mouse Mammary Tumor Virus Genes during Development of the BALB/c Mammary Gland. Janice E. Knepper, Daniel Medina, and Janet S. Butel...... 518-521

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Mutagenesis of the Avian Erythroblastosis Virus erbB Coding Region: An Intact Extracellular Domain Is Not Required for Oncogenic Transformation. Mansour Bassiri and Martin L. Privalsky ...... 525-530 BACTERIAL VIRUSES Interruption-Deficient Mutants of Bacteriophage T5: Analysis of Single-Site Mutants. Marc Rhoades ...... 203-209 PLANT VIRUSES Regulation of Expression of the Wound Tumor Virus Genome in Persistently Infected Vector Cells Is Related to Change in Translational Activity of Viral Transcripts. Andrew J. Peterson and Donald L. Nuss ...... 195-202 VIRAL PATHOGENESIS AND IMMUNITY Characterization of a Progressive Neurodegenerative Disease Induced by a Temperature-Sensitive Moloney Murine Leukemia Virus . John A. Bilello, Olin M. Pitts, and Paul M. Hoffman ...... 234-241 Eradication of Herpes Simplex Virus Persistence in Rat Trigeminal Ganglia by Retrograde Axoplasmic Transport. Yuzo Iwasaki, Teiji Yamamoto, Hidehiko Konno, Hideaki lizuka, and Hiroko Kudo ...... 242-248 A Mouse c-myc Retrovirus Transforms Established Fibroblast Lines In Vitro and Induces Monocyte-Macrophage Tumors In Vivo. William R. Baumbach, Elizabeth J. Keath, and Michael D. Cole ...... 276-283 Genetic Reassortants of Lymphocytic Choriomeningitis Virus: Unexpected Disease and Mechanism of Pathogenesis. Yves Riviere and Michael B. A. Oldstone 363-368 Mechanisms of Lymphocytic Choriomeningitis Virus-Induced Hemopoietic Dysfunction. A. Randrup Thomsen, P. Pisa, K. Bro-J0rgensen, and R. Kiessling ...... 428-433 Transformation of T-Lymphoid Cells by Abelson Murine Leukemia Virus. Martin L. Scott, Mark M. Davis, and Mark B. Feinberg ...... 434-443 Site-Specific Alteration of Murine Hepatitis Virus Type 4 Peplomer Glycoprotein E2 Results in Reduced Neurovirulence. R. G. Dalziel, P. W. Lampert, P. J. Talbot, and M. J. Buchmeier ...... 463-471 Expression of Defective Measles Virus Genes in Brain Tissues of Patients with Subacute Sclerosing Panencephalitis. Knut Baczko, Uwe G. Liebert, Martin Billeter, Roberto Cattaneo, Herbert Budka, and Volker ter Meulen 472-478 Relationship between Poliovirus Neutralization and Aggregation. Adri A. M. Thomas, Raf Vrijsen, and Albert Boeye...... 479-485 Herpes Simplex Virus (HSV)-Specific Human T-Cell Clones Recognize HSV Glycoprotein D Expressed by a Recombinant Vaccinia Virus. Joyce M.

Zarling, Patricia A. Moran, Laurence A. Lasky, and Bernard Moss ...... 506-509 Interferon Response in Normal and Aleutian Disease Virus-Infected Mink. Danny L. Wiedbrauk, William J. Hadlow, Larry C. Ewalt, and Donald L. Lodmell ...... 514-517

Date of Issue: 18 July 1986