Rabbit Anti-Human PDPN monoclonal antibody, clone KN42-32 (DCABH-2116) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Target Podoplanin

Immunogen Recombinant

Isotype IgG

Source/Host Rabbit

Species Reactivity Human

Clone KN42-32

Purification Protein A purified.

Conjugate Unconjugated

Applications WB, IHC

Cellular Localization Membrane.

Positive Control Human lung cells lysates, human lung tissue, human colon cancer tissue.

Format Liquid

Size 100 μl

Buffer 1×TBS (pH7.4), 1% BSA, 40% Glycerol.

Preservative 0.05% Sodium Azide

Storage Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Warnings For research use only

BACKGROUND

Introduction Puromycin aminonucleoside nephrosis (PAN) is a rat model for human minimal change nephropathy. During PAN, severe proteinuria is induced that is paralleled by a reduced expression of a rat podocyte protein, named podoplanin. Podoplanin, also known as glycoprotein

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Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved 38 (gp38) is a type I membrane protein. Podoplanin localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes.

Keywords Aggrus;Glycoprotein 36 KD;Glycoprotein 36;gp 36;GP 38;GP 40;gp36;GP38;GP40;HT1A 1;HT1A1;hT1alpha 1;hT1alpha 2;hT1alpha1;hT1alpha2;Lung type I cell membrane associated glycoprotein;Lung type I cell membrane associated glycoprotein isoform a;Lung type I cell membrane associated glycoprotein T1A 2;OTS 8;OTS8;OTTHUMP00000009640;OTTHUMP00000044504;PA2.26;PA2.26 antigen;Pdpn;PDPN_HUMAN;Podoplanin;PSEC0003;PSEC0025;T1 alpha;T1 ALPHA ;T1- alpha;T1A 2;T1A;TI1A;TIA 2;TIA2 antibody

GENE INFORMATION

Entrez Gene ID 10630

UniProt ID Q86YL7

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Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved