STOXX® EUROPE 600 HEALTH CARE INDEX

Components1

Company Supersector Country Weight (%)

ROCHE HLDG P null null 15.76 NOVARTIS null null 13.62 ASTRAZENECA null null 9.03 NOVO NORDISK B null null 8.24 SANOFI null null 7.07 GLAXOSMITHKLINE null null 5.88 BAYER null null 3.65 ESSILORLUXOTTICA null null 3.13 LONZA null null 3.13 PHILIPS null null 2.77 ALCON null null 2.08 GENMAB null null 1.69 MERCK null null 1.38 FRESENIUS null null 1.31 SONOVA null null 1.16 COLOPLAST B null null 1.13 SMITH & NEPHEW null null 1.11 STRAUMANN null null 1.04 FRESENIUS MEDICAL CARE null null 0.98 ARGENX null null 0.96 NOVOZYMES null null 0.92 EUROFINS SCIENTIFIC null null 0.82 SIEMENS HEALTHINEERS null null 0.79 UCB null null 0.76 SARTORIUS PREF. null null 0.71 GN STORE NORD null null 0.66 QIAGEN null null 0.65 SARTORIUS STEDIM BIOTECH null null 0.64 CHR HANSEN HLDG null null 0.56 GRIFOLS null null 0.49 GETINGE B null null 0.47 VIFOR PHARMA null null 0.42 CARL ZEISS MEDITEC null null 0.41 ORPEA null null 0.39 DECHRA PHARMACEUTICALS null null 0.38 AMBU 'B' null null 0.38 AMPLIFON null null 0.37 EVOTEC null null 0.35 RECORDATI null null 0.34 DEMANT null null 0.34 HIKMA PHARMACEUTICALS null null 0.33 CONVATEC PLC null null 0.32 BIOMERIEUX null null 0.32 ELEKTA B null null 0.30 TECAN null null 0.30 DIASORIN null null 0.28 ORION B null null 0.28 GENUS null null 0.27 SIEGFRIED 'R' null null 0.23 IPSEN null null 0.23 UDG HEALTHCARE PUBLIC null null 0.22 SWEDISH ORPHAN BIOVITRUM null null 0.21 GALAPAGOS null null 0.19 GERRESHEIMER null null 0.18 IDORSIA LIMITED null null 0.18 MORPHOSYS null null 0.16

1 Based on the last periodic review implementation