Appendix III: 2005 Publications

RI MUHC Investigators affiliated with Department of Medicine

Antel, Jack Perry

Antel, Jack Perry Validation Status ** Peer-Reviewed Articles, Case Reports, Clinical Trials Antel J. Oligodendrocyte/myelin injury and repair as a function of the central nervous system environment. Clin Neurol Neurosurg 108(3):245-9, 2006 [Published electronically in 2005]. Peer-Reviewed Article PubMed: 16384636 V Arbour N, Rastikerdar E, McCrea E, Lapierre Y, Dorr J, Bar-Or A, Antel JP. Upregulation of TRAIL expression on human T lymphocytes by interferon beta and glatiramer acetate. Mult Scler 11(6):652-7, 2005. Peer-Reviewed Article PubMed: 16320724 V Biernacki K, Antel JP, Blain M, Narayanan S, Arnold DL, Prat A. Interferon beta promotes nerve growth factor secretion early in the course of multiple sclerosis. Arch Neurol 62(4):563-8, 2005. Peer-Reviewed Article PubMed: 15824253 V Jack CS, Arbour N, Manusow J, Montgrain V, Blain M, McCrea E, Shapiro A, Antel JP. TLR signaling tailors innate immune responses in human microglia and astrocytes. J Immunol 175(7):4320-30, 2005. Peer-Reviewed Article PubMed: 16177072 V Magnus T, Schreiner B, Korn T, Jack C, Guo H, Antel J, Ifergan I, Chen L, Bischof F, Bar-Or A, Wiendl H. Microglial expression of the B7 family member B7 homolog 1 confers strong immune inhibition: implications for immune responses and autoimmunity in the CNS. J Neurosci 25(10):2537-46, 2005. Peer-Reviewed Article PubMed: 15758163 V Prat A, Biernacki K, Antel JP. Th1 and Th2 lymphocyte migration across the human BBB is specifically regulated by interferon beta and copolymer-1. J Autoimmun 24(2):119-24, 2005. Peer-Reviewed Article PubMed: 15829404 V Prat A, Biernacki K, Saroli T, Orav JE, Guttmann CR, Weiner HL, Khoury SJ, Antel JP. Kinin B1 receptor expression on multiple sclerosis mononuclear cells: correlation with magnetic resonance imaging T2-weighted lesion volume and clinical disability. Arch Neurol 62(5):795-800, 2005. Peer-Reviewed Article PubMed: 15883268 V Wiendl H, Feger U, Mittelbronn M, Jack C, Schreiner B, Stadelmann C, Antel J, Brueck W, Meyermann R, Bar-Or A, Kieseier BC, Weller M. Expression of the immune-tolerogenic major histocompatibility molecule HLA-G in multiple sclerosis: implications for CNS immunity. Brain 128(Pt 11):2689-704, 2005. Peer-Reviewed Article PubMed: 16123145 V Review Articles, Invited Publications Jack C, Ruffini F, Bar-Or A, Antel JP. Microglia and multiple sclerosis. J Neurosci Res 81(3):363-73, 2005. Review Article PubMed: 15948188 V

Barkun, Alan Nicholas Validation Status ** Peer-Reviewed Articles, Case Reports, Clinical Trials Armstrong D, Veldhuyzen van Zanten SJ, Barkun AN, Chiba N, Thomson AB, Smyth S, Sinclair P, Chakraborty B, White RJ.

Heartburn-dominant, uninvestigated dyspepsia: a comparison of 'PPI-start' and 'H2-RA-start' management strategies in primary care--the CADET-HR Study. Aliment Pharmacol Ther 21(10):1189-202, 2005. Peer-Reviewed Clinical Trial Report PubMed: 15882239 V Bardou M, Toubouti Y, Benhaberou-Brun D, Rahme E, Barkun AN. Meta-analysis: proton-pump inhibition in high-risk patients with acute peptic ulcer bleeding. Aliment Pharmacol Ther 21(6):677-86, 2005. Peer-Reviewed Article PubMed: 15771753 V Chan G, Barkun J, Barkun AN, Valois E, Cohen A, Friedman G, Parent J, Love J, Enns R, Baffis V, Jabbari M, Szego P, Stein L, Abraham N. The role of ciprofloxacin in prolonging polyethylene biliary stent patency: a multicenter, double-blinded effectiveness study.

J Gastrointest Surg 9(4):481-8, 2005. Peer-Reviewed Clinical Trial Report PubMed: 15797227 V Varadarajulu S, Eloubeidi MA, Patel RS, Mulcahy HE, Barkun A, Jowell P, Libby E, Schutz S, Nickl NJ, Cotton PB. The yield and the predictors of esophageal pathology when upper endoscopy is used for the initial evaluation of dysphagia.

Gastrointest Endosc 61(7):804-8, 2005. Peer-Reviewed Article PubMed: 15933679 V Veldhuyzen van Zanten SJ, Chiba N, Armstrong D, Barkun A, Thomson A, Smyth S, Escobedo S, Lee J, Sinclair P. A randomized trial comparing omeprazole, ranitidine, cisapride, or placebo in helicobacter pylori negative, primary care patients with dyspepsia: the CADET-HN Study. Am J Gastroenterol 100(7):1477-88, 2005. Peer-Reviewed Clinical Trial Report PubMed: 15984968 V See: Dial, Sandra (Dial S et al).

See: Fallone, Carlo A (Bensoussan K et al).

See: Fallone, Carlo A (Degl' Innocenti A et al).

See: Fallone, Carlo A (El-Dika S et al).

Barré, Paul Eugène Validation Status ** Peer-Reviewed Articles, Case Reports, Clinical Trials Devins GM, Mendelssohn DC, Barre PE, Taub K, Binik YM. Predialysis psychoeducational intervention extends survival in CKD: a 20-year follow-up. Am J Kidney Dis 46(6):1088-98, 2005. Peer-Reviewed Article PubMed: 16310575 V Hoffer LJ, Saboohi F, Golden M, Barre PE. Cobalamin dose regimen for maximum homocysteine reduction in end-stage renal disease. Metabolism 54(6):835-40, 2005. Peer-Reviewed Clinical Trial Report PubMed: 15931623 V Levin A, Djurdjev O, Thompson C, Barrett B, Ethier J, Carlisle E, Barre P, Magner P, Muirhead N, Tobe S, Tam P, Wadgymar JA, Kappel J, Holland D, Pichette V, Shoker A, Soltys G, Verrelli M, Singer J. Canadian randomized trial of hemoglobin maintenance to prevent or delay left ventricular mass growth in patients with CKD. Am J Kidney Dis 46(5):799-811, 2005. Peer-Reviewed Clinical Trial Report PubMed: 16253719 V Lindberg JS, Culleton B, Wong G, Borah MF, Clark RV, Shapiro WB, Roger SD, Husserl FE, Klassen PS, Guo MD, Albizem MB, Coburn JW. Cinacalcet HCl, an oral calcimimetic agent for the treatment of secondary hyperparathyroidism in hemodialysis and peritoneal dialysis: a randomized, double-blind, multicenter study. J Am Soc Nephrol 16(3):800-7, 2005. Peer-Reviewed Clinical Trial Report PubMed: 15689407 NV Parfrey PS, Foley RN, Wittreich BH, Sullivan DJ, Zagari MJ, Frei D. Double-blind comparison of full and partial anemia correction in incident hemodialysis patients without symptomatic heart disease. J Am Soc Nephrol 16(7):2180-9, 2005. Peer-Reviewed Clinical Trial Report PubMed: 15901766 NV

Becklake, Margaret R Validation Status ** Peer-Reviewed Articles, Case Reports, Clinical Trials Bagatin E, Neder JA, Nery LE, Terra-Filho M, Kavakama J, Castelo A, Capelozzi V, Sette A, Kitamura S, Favero M, Moreira-Filho DC, Tavares R, Peres C, Becklake MR. Non-malignant consequences of decreasing asbestos exposure in the Brazil chrysotile mines and mills. Occup Environ Med 62(6):381-9, 2005. Peer-Reviewed Article PubMed: 15901885 V Becklake MR, Ghezzo H, Ernst P. Childhood predictors of smoking in adolescence: a follow-up study of Montreal schoolchildren. Cmaj 173(4):377-9, 2005. Peer-Reviewed Article PubMed: 16103510 V Naidoo RN, Robins TG, Seixas N, Lalloo UG, Becklake M. Differential respirable dust related lung function effects between current and former South African coal miners. Int Arch Occup Environ Health 78(4):293-302, 2005. Peer-Reviewed Article PubMed: 15785947 V

Behr, Marcel A Validation Status ** Peer-Reviewed Articles, Case Reports, Clinical Trials Charlet D, Mostowy S, Alexander D, Sit L, Wiker HG, Behr MA. Reduced expression of antigenic proteins MPB70 and MPB83 in Mycobacterium bovis BCG strains due to a start codon mutation in sigK. Mol Microbiol 56(5):1302-13, 2005. Peer-Reviewed Article PubMed: 15882422 V Mostowy S, Inwald J, Gordon S, Martin C, Warren R, Kremer K, Cousins D, Behr MA. Revisiting the evolution of Mycobacterium bovis. J Bacteriol 187(18):6386-95, 2005. Peer-Reviewed Article PubMed: 16159772 V Scott AN, Menzies D, Tannenbaum TN, Thibert L, Kozak R, Joseph L, Schwartzman K, Behr MA. Sensitivities and specificities of spoligotyping and mycobacterial interspersed repetitive unit-variable-number tandem repeat typing methods for studying molecular epidemiology of tuberculosis. J Clin Microbiol 43(1):89-94, 2005. Peer-Reviewed Article PubMed: 15634955 V Semret M, Alexander DC, Turenne CY, de Haas P, Overduin P, van Soolingen D, Cousins D, Behr MA. Genomic polymorphisms for Mycobacterium avium subsp. paratuberculosis diagnostics. J Clin Microbiol 43(8):3704-12, 2005. Peer-Reviewed Article PubMed: 16081899 V Somerville W, Thibert L, Schwartzman K, Behr MA. Extraction of Mycobacterium tuberculosis DNA: a question of containment. J Clin Microbiol 43(6):2996-7, 2005. Peer-Reviewed Article PubMed: 15956443 V Spreadbury CL, Pallen MJ, Overton T, Behr MA, Mostowy S, Spiro S, Busby SJ, Cole JA. Point mutations in the DNA- and cNMP-binding domains of the homologue of the cAMP receptor protein (CRP) in Mycobacterium bovis BCG: implications for the inactivation of a global regulator and strain attenuation. Microbiology 151(Pt 2):547-56, 2005. Peer-Reviewed Article PubMed: 15699203 V Verver S, Warren RM, Beyers N, Richardson M, van der Spuy GD, Borgdorff MW, Enarson DA, Behr MA, van Helden PD.

Rate of reinfection tuberculosis after successful treatment is higher than rate of new tuberculosis. Am J Respir Crit Care Med 171(12):1430-5, 2005. Peer-Reviewed Article PubMed: 15831840 V Review Articles, Invited Publications Mostowy S, Behr MA. The origin and evolution of Mycobacterium tuberculosis. Clin Chest Med 26(2):207-16, v-vi, 2005. Review Article PubMed: 15837106 V

Bennett, Hugh Patrick Joseph Validation Status ** Peer-Reviewed Articles, Case Reports, Clinical Trials Cadieux B, Chitramuthu BP, Baranowski D, Bennett HP. The zebrafish progranulin gene family and antisense transcripts. BMC Genomics 6:156, 2005 [Electronic publication]. Peer-Reviewed Article PubMed: 16277664 V

Bernard, Nicole Flore Validation Status ** Peer-Reviewed Articles, Case Reports, Clinical Trials Cox JH, Ferrari G, Kalams SA, Lopaczynski W, Oden N, D'Souza M P [and Elispot Collaborative Study Group]. Results of an ELISPOT proficiency panel conducted in 11 laboratories participating in international human immunodeficiency virus type 1 vaccine trials. AIDS Res Hum Retroviruses 21(1):68-81, 2005. Peer-Reviewed Article PubMed: 15665646 V Makedonas G, Bruneau J, Alary M, Tsoukas CM, Lowndes CM, Lamothe F, Bernard NF. Comparison of HIV-specific CD8 T-cell responses among uninfected individuals exposed to HIV parenterally and mucosally. Aids 19(3):251-9, 2005. Peer-Reviewed Article PubMed: 15718835 V Peretz Y, Alter G, Boisvert MP, Hatzakis G, Tsoukas CM, Bernard NF. Human immunodeficiency virus (HIV)-specific gamma interferon secretion directed against all expressed HIV genes: relationship to rate of CD4 decline. J Virol 79(8):4908-17, 2005. Peer-Reviewed Article PubMed: 15795276 V See: Routy, Jean-Pierre (Bukczynski J et al).

See: Routy, Jean-Pierre (Serghides L et al).

See: Routy, Jean-Pierre (Troesch M et al).

Bernatsky, Sasha R Validation Status ** Peer-Reviewed Articles, Case Reports, Clinical Trials Bernatsky S, Boivin JF, Joseph L, Manzi S, Ginzler E, Urowitz M, Gladman D, Fortin P, Gordon C, Barr S, Edworthy S, Bae SC, Petri M, Sibley J, Isenberg D, Rahman A, Steinsson K, Aranow C, Dooley MA, Alarcon GS et al. Race/ethnicity and cancer occurrence in systemic lupus erythematosus. Arthritis Rheum 53(5):781-4, 2005. Peer-Reviewed Article PubMed: 16208671 V Bernatsky S, Boivin JF, Joseph L, Rajan R, Zoma A, Manzi S, Ginzler E, Urowitz M, Gladman D, Fortin PR, Petri M, Edworthy S, Barr S, Gordon C, Bae SC, Sibley J, Isenberg D, Rahman A, Aranow C, Dooley MA et al. An international cohort study of cancer in systemic lupus erythematosus. Arthritis Rheum 52(5):1481-90, 2005. Peer-Reviewed Article PubMed: 15880596 V

* Note: Publications for investigators with an asterisk are based on PubMed search only and have not been validated with the 15-Sep-06 Document produced by the Grant Management and Research Statistics Department of the Research Institute of ** V: Validated ; PV: Partially Validated ; NV : Not Validated (see Page 5 of 90 Bernatsky, Sasha R Bernatsky S, Clarke A, Abrahamowicz M, Neville C, Karp I, Pineau CA. A comparison of prospective and retrospective evaluations of the Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index for systemic lupus erythematosus. J Rheumatol 32(5):820-3, 2005. Peer-Reviewed Article PubMed: 15868615 V Bernatsky S, Dobkin PL, De Civita M, Penrod JR. Co-morbidity and physician use in fibromyalgia. Swiss Med Wkly 135(5-6):76-81, 2005. Peer-Reviewed Article PubMed: 15729611 V Bernatsky S, Hudson M, Suissa S. Anti-rheumatic drug use and risk of hospitalization for congestive heart failure in rheumatoid arthritis. Rheumatology (Oxford) 44(5):677-80, 2005. Peer-Reviewed Article PubMed: 15784627 V Bernatsky S, Joseph L, Belisle P, Boivin JF, Rajan R, Moore A, Clarke A. Bayesian modelling of imperfect ascertainment methods in cancer studies. Stat Med 24(15):2365-79, 2005. Peer-Reviewed Article PubMed: 15977290 V Bernatsky S, Ramsey-Goldman R, Rajan R, Boivin JF, Joseph L, Lachance S, Cournoyer D, Zoma A, Manzi S, Ginzler E, Urowitz M, Gladman D, Fortin PR, Edworthy S, Barr S, Gordon C, Bae SC, Sibley J, Steinsson K, Nived O, Sturfelt G, St Pierre Y, Clarke A. Non-Hodgkin's lymphoma in systemic lupus erythematosus. Ann Rheum Dis 64(10):1507-9, 2005. Peer-Reviewed Article PubMed: 16162903 V See: Clarke, Ann Elaine (Clarke AE et al).

See: Da Costa, Deborah M (Da Costa D et al).

See: Pineau, Christian A (Costa DD et al).

Review Articles, Invited Publications Bernatsky S, Ramsey-Goldman R, Clarke A. Exploring the links between systemic lupus erythematosus and cancer. Rheum Dis Clin North Am 31(2):387-402, viii-ix, 2005. Review Article PubMed: 15922152 V

Bitton, Alain Validation Status ** Peer-Reviewed Articles, Case Reports, Clinical Trials Daly MJ, Pearce AV, Farwell L, Fisher SA, Latiano A, Prescott NJ, Forbes A, Mansfield J, Sanderson J, Langelier D, Cohen A, Bitton A, Wild G, Lewis CM, Annese V, Mathew CG, Rioux JD. Association of DLG5 R30Q variant with inflammatory bowel disease. Eur J Hum Genet 13(7):835-9, 2005. Peer-Reviewed Article PubMed: 15841097 V See: Wild, Gary Edward (Waschke KA et al).

Blostein, Rhoda * Validation Status ** Peer-Reviewed Articles, Case Reports, Clinical Trials Segall L, Mezzetti A, Scanzano R, Gargus JJ, Purisima E, Blostein R. Alterations in the alpha2 isoform of Na,K-ATPase associated with familial hemiplegic migraine type 2. Proc Natl Acad Sci U S A 102(31):11106-11, 2005. Peer-Reviewed Article PubMed: 16037212 NV Zouzoulas A, Dunham PB, Blostein R. The effect of the gamma modulator on Na/K pump activity of intact mammalian cells. J Membr Biol 204(1):49-56, 2005. Peer-Reviewed Article PubMed: 16007503 NV

Bourbeau, Jean Validation Status ** Peer-Reviewed Articles, Case Reports, Clinical Trials Gadoury MA, Schwartzman K, Rouleau M, Maltais F, Julien M, Beaupre A, Renzi P, Begin R, Nault D, Bourbeau J. Self-management reduces both short- and long-term hospitalisation in COPD. Eur Respir J 26(5):853-7, 2005. Peer-Reviewed Clinical Trial Report PubMed: 16264046 V Hamelin ME, Cote S, Laforge J, Lampron N, Bourbeau J, Weiss K, Gilca R, DeSerres G, Boivin G. Human metapneumovirus infection in adults with community-acquired pneumonia and exacerbation of chronic obstructive pulmonary disease. Clin Infect Dis 41(4):498-502, 2005. Peer-Reviewed Article PubMed: 16028158 V Maltais F, Bourbeau J, Lacasse Y, Shapiro S, Perrault H, Penrod JR, Baltzan M, Rouleau M, Julien M, Paradis B, Audet R, Hernandez P, Levy RD, Camp P, Lecours R, Picard D, Bernard S. A Canadian, multicentre, randomized clinical trial of home-based pulmonary rehabilitation in chronic obstructive pulmonary disease: rationale and methods. Can Respir J 12(4):193-8, 2005. Peer-Reviewed Clinical Trial Report PubMed: 16003455 V Schlecht NF, Schwartzman K, Bourbeau J. Dyspnea as clinical indicator in patients with chronic obstructive pulmonary disease. Chron Respir Dis 2(4):183-91, 2005. Peer-Reviewed Article PubMed: 16541601 V Wang Q, Bourbeau J. Outcomes and health-related quality of life following hospitalization for an acute exacerbation of COPD. Respirology 10(3):334-40, 2005. Peer-Reviewed Article PubMed: 15955146 V See: Menzies, Dick (McKnight J et al).

Chapters, Books, Conference Proceedings Bourbeau J, Perrault H. Physiologic basis for pulmonary rehabilitation of chronic obstructive pulmonary disease. In: Physiologic Basis of Respiratory Disease, pp 733-44, Hamid Q, Shannon J, Martin J (eds), B.C. Decker, Inc., Hamilton, Ontario, 2005. V Chapter ISBN: 1550092367 Bourbeau J, Soicher J. The challenge of self-management. In: Pulmonary Rehabilitation, pp 353-61, Donner CF, Ambrosio N, Goldstein RS (eds), London, Hodder Education, 2005. Chapter ISBN: 9780340810170 V

Bourque, Cha