The Lectures of Carl Wernicke Robert Miller
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Work-Up of Globus: Assessing the Benefits of Neck Ultrasound and Videofluorography
View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by Helsingin yliopiston digitaalinen arkisto Eur Arch Otorhinolaryngol (2017) 274:931–937 DOI 10.1007/s00405-016-4307-8 LARYNGOLOGY Work-up of globus: assessing the benefits of neck ultrasound and videofluorography 1 1 1 1 Pia Ja¨rvenpa¨a¨ • Taru Ilmarinen • Ahmed Geneid • Petra Pietarinen • 1 1 1 Teemu J. Kinnari • Heikki Rihkanen • Johanna Ruohoalho • Mari Markkanen- 1 1 2 1 Leppa¨nen • Leif Ba¨ck • Perttu Arkkila • Leena-Maija Aaltonen Received: 15 July 2016 / Accepted: 12 September 2016 / Published online: 17 September 2016 Ó Springer-Verlag Berlin Heidelberg 2016 Abstract Globus patients with normal ear, nose, and throat benefit to evaluate the globus etiology in patients whose (ENT) status are a diagnostic challenge. The symptom may ENT status was normal. Half the globus patients suffered be long lasting and cause concern about malignancy, from persistent symptoms after a 3- and 6-year follow-up, leading to possibly unnecessary further investigation. The indicating that globus may cause discomfort chronically. aim of the study was to assess whether radiological However, no patients developed malignancies during a examinations are useful in globus diagnostics, how often 3-year follow-up. patients suffer from persistent globus, and whether globus patients with normal ENT status develop a malignancy Keywords Globus Á Malignancy Á Globus diagnostics Á during a follow-up. We reviewed medical records of all 76 Follow-up globus patients referred to Helsinki University Hospital, Department of Otorhinolaryngology-Head and Neck Sur- gery in 2009. Patient history and findings in physical and Introduction radiological examinations were registered. -
Gesellschaft Und Psychiatrie in Österreich 1945 Bis Ca
1 VIRUS 2 3 VIRUS Beiträge zur Sozialgeschichte der Medizin 14 Schwerpunkt: Gesellschaft und Psychiatrie in Österreich 1945 bis ca. 1970 Herausgegeben von Eberhard Gabriel, Elisabeth Dietrich-Daum, Elisabeth Lobenwein und Carlos Watzka für den Verein für Sozialgeschichte der Medizin Leipziger Universitätsverlag 2016 4 Virus – Beiträge zur Sozialgeschichte der Medizin Die vom Verein für Sozialgeschichte der Medizin herausgegebene Zeitschrift versteht sich als Forum für wissenschaftliche Publikationen mit empirischem Gehalt auf dem Gebiet der Sozial- und Kulturgeschichte der Medizin, der Geschichte von Gesundheit und Krankheit sowie an- grenzender Gebiete, vornehmlich solcher mit räumlichem Bezug zur Republik Österreich, ihren Nachbarregionen sowie den Ländern der ehemaligen Habsburgermonarchie. Zudem informiert sie über die Vereinstätigkeit. Die Zeitschrift wurde 1999 begründet und erscheint jährlich. Der Virus ist eine peer-reviewte Zeitschrift und steht Wissenschaftlerinnen und Wissenschaftlern aus allen Disziplinen offen. Einreichungen für Beiträge im engeren Sinn müssen bis 31. Okto- ber, solche für alle anderen Rubriken (Projektvorstellungen, Veranstaltungs- und Aus stel lungs- be richte, Rezensionen) bis 31. Dezember eines Jahres als elektronische Dateien in der Redak- tion einlangen, um für die Begutachtung und gegebenenfalls Publikation im darauf fol genden Jahr berücksichtigt werden zu können. Nähere Informationen zur Abfassung von Bei trägen sowie aktuelle Informationen über die Vereinsaktivitäten finden Sie auf der Homepage des Ver eins (www.sozialgeschichte-medizin.org). Gerne können Sie Ihre Anfragen per Mail an uns richten: [email protected] Bibliografische Information der Deutschen Nationalbibliothek Die Deutsche Nationalbibliothek verzeichnet diese Publikation in der Deutschen Nationalbi - bli o grafie; detaillierte bibliografische Daten sind im Internet über http://dnb.d-nb.de abrufbar. Das Werk einschließlich aller seiner Teile ist urheberrechtlich geschützt. -
1 Language and the Brain Colin Phillips, University of Maryland
Language and the Brain Colin Phillips, University of Maryland & Kuniyoshi L. Sakai, University of Tokyo Many species have evolved sophisticated communication systems, but human language stands out as special in at least two respects, both of which contribute to the vast expressive power of human language. First, humans are able to memorize many thousands of words, each of which encodes a piece of meaning using an arbitrary sound or gesture. By some estimates, during the preschool and primary school years a child learns an average of 5-10 new words per day, on the way to attaining a vocabulary of 20,000-50,000 words by adulthood. Second, humans are able to combine words to form sentences and discourses, making it possible to communicate infinitely many different messages, and providing the basis of human linguistic creativity. Furthermore, speakers are able to generate and understand novel messages quickly and effortlessly, on the scale of hundreds of milliseconds. Linguists and cognitive neuroscientists are interested in understanding what special properties of the human brain make such feats possible. Efforts to answer this question go back at least 150 years. A great deal of attention has been given to the issue of which regions of the human brain are most important for language, first using findings from brain-damaged patients, and in recent years adding a wealth of new information from modern non-invasive brain recording techniques such as positron emission tomography (PET) and functional magnetic resonance imaging (fMRI). However, it is important to bear in mind that knowing where language is supported in the human brain is just one step on the path to finding what are the special properties of those brain regions that make language possible. -
2 Türk Psikiyatri Dergisi 2 Turkish Journal of Psychiatry
2 Türk Psikiyatri Dergisi 2 Turkish Journal of Psychiatry CİLT | Volume 27 GÜZ | Autumn 2016 EK | Supplement 2: 52. ULUSAL PSİKİYATRİ KONGRESİ TÜRKİYE SİNİR VE ABSTRACTS RUH SAĞLIĞI ISSN 1300 – 2163 DERNEĞİ 2 Türk Psikiyatri Dergisi 2 Mart, Haziran, Eylül ve Aralık aylarında olmak üzere yılda 4 sayı çıkar Turkish Journal of Psychiatry Four issues annually: March, June, September, December CİLT | Volume 27 GÜZ | Autumn 2016 Türkiye Sinir ve Ruh Sağlığı Derneği EK | Supplement 2 tarafından yayınlanmaktadır. ISSN 1300 – 2163 www.turkpsikiyatri.com Türk Psikiyatri Dergisi Bu Sayının Yayın Yönetmeni /Editor in Chief of this Issue Doç. Dr. Semra Ulusoy Kaymak Türkiye Sinir ve Ruh Sağlığı Derneği adına Sahibi ve Sorumlu Müdürü Kongre Başkanları Published by Turkish Association of Nervous and Mental Health Prof. Dr. M. Orhan Öztürk E. Timuçin Oral - Ekrem Cüneyt Evren Düzenleme Kurulu Yayın Yönetmeni/ Editor in Chief Ekrem Cüneyt Evren (Başkan) Prof. Dr. Aygün Ertuğrul Ercan Dalbudak Selim Tümkaya Yazışma Adresi / Corresponding Address Semra Ulusoy Kaymak PK 401, Yenişehir 06442 Ankara Sinan Aydın (Genç Üye) Yönetim Yeri / Editorial Office Bu Sayının Yayın Yönetmen Yardımcıları Kenedi Cad. 98/4, Kavaklıdere, Ankara / Assoc. Editors in Chief of this Issue Telefon: (0-312) 427 78 22 Faks: (0-312) 427 78 02 Sinan Aydın Esra Kabadayı Yayın Türü / Publication Category Selim Tümkaya Yaygın, Süreli, Bilimsel Yayın Yayın Hizmetleri / Publishing Services BAYT Bilimsel Araştırmalar Reklam / Advertisements Basın Yayın ve Tanıtım Ltd. Şti. Reklam koşulları ve diğer ayrıntılar için yayın yönetmeniyle Tel (0-312) 431 30 62, Faks: (0-312) 431 36 02 ilişkiye geçilmesi gerekmektedir. E-posta: [email protected] (Dergide yer alan yazılarda belirtilen görüşlerden yazarlar sorumludur. -
Globus Hystericus Management and Treatment Concerns, and Utility of Antidepressants
INTERNATIONAL JOURNAL OF SCIENTIFIC PROGRESS AND RESEARCH (IJSPR) ISSN: 2349-4689 Issue 150, Volume 50, Number 01, August 2018 Globus Hystericus Management and Treatment Concerns, and Utility of Antidepressants Raja Salman Khurshid1,Seema Batool Shah2, Mohammad Maqbool Dar3 1Consultant ENT, Department of health, 2Postgraduate scholar, Department of Psychiatry,3Professor and Head, Department of Psychiatry 1J&K Health services, 1,2Government Medical College, Srinagar Abstract: Objective/Hypothesis: To study the treatment response oesophageal sphincter (UOS), and local anatomic of Globus pharyngeus to ppi/prokinetic combination, and the abnormalities.1,3,4Several reports have indicated that there role of antidepressants in non-responders. The purpose of this is a close relationship between esophageal acid reflux and study is to devise a guideline for managing Globus pharyngeus globus sensation. It has been reported that there is a high which otherwise is a poorly understood and managed prevalence of esophageal motor abnormalities, including condition. Study design: It is a prospective non-randomised 4,5 study where OPD visiting patients have been followed over a upper esophageal sphincter (UES) dysfunction , in course of 3 to 15 months. Methods: 54 patients of Globus patients who complain of globus sensation resistant to PPI pharyngeus diagnosed, with any organic condition ruled out, therapy without any organic diseases, although the were put on esomeprazole-domperidone/levosulpride evidence obtained has been inconsistent. It has been combination. Patients were followed over 3 weeks and 6 weeks reported that several psychological problems or social period. The non-reponders were put on antidepressant stress have often been considered to cause or trigger fluoxetine in addition. -
Oropharyngeal Dysphagia As a Geriatric Syndrome Open Access to Scientific and Medical Research DOI
Journal name: Clinical Interventions in Aging Article Designation: Review Year: 2016 Volume: 11 Clinical Interventions in Aging Dovepress Running head verso: Baijens et al Running head recto: Oropharyngeal dysphagia as a geriatric syndrome open access to scientific and medical research DOI: http://dx.doi.org/10.2147/CIA.S107750 Open Access Full Text Article REVIEW European Society for Swallowing Disorders – European Union Geriatric Medicine Society white paper: oropharyngeal dysphagia as a geriatric syndrome Laura WJ Baijens,1 Pere Clavé,2,3 Abstract: This position document has been developed by the Dysphagia Working Group, Patrick Cras,4 Olle Ekberg,5 a committee of members from the European Society for Swallowing Disorders and the European Alexandre Forster,6 Gerald F Union Geriatric Medicine Society, and invited experts. It consists of 12 sections that cover all 7 8 Kolb, Jean-Claude Leners, aspects of clinical management of oropharyngeal dysphagia (OD) related to geriatric medicine 9 Stefano Masiero, Jesús Mateos- and discusses prevalence, quality of life, and legal and ethical issues, as well as health economics Nozal,10 Omar Ortega,2,3 David and social burden. OD constitutes impaired or uncomfortable transit of food or liquids from the G Smithard,11 Renée Speyer,12 oral cavity to the esophagus, and it is included in the World Health Organization’s classification Margaret Walshe13 For personal use only. of diseases. It can cause severe complications such as malnutrition, dehydration, respiratory 1Department of Otorhinolaryngology – Head infections, aspiration pneumonia, and increased readmissions, institutionalization, and mor- and Neck Surgery, Maastricht University Medical Center, Maastricht, the Netherlands; bimortality. OD is a prevalent and serious problem among all phenotypes of older patients as 2Gastrointestinal Physiology Laboratory, oropharyngeal swallow response is impaired in older people and can cause aspiration. -
Paul Ferdinand Schilders Bedeutendste Neurowissenschaftliche Und Neurologische Arbeiten
Paul Ferdinand Schilders bedeutendste neurowissenschaftliche und neurologische Arbeiten Dissertation zur Erlangung des akademischen Grades Dr. med. an der Medizinischen Fakultät der Universität Leipzig eingereicht von: Martin Jahn geboren am 11.08.1982 in Tübingen angefertigt in der: Forschungsstelle für die Geschichte der Psychiatrie Klinik und Poliklinik für Psychiatrie und Psychotherapie Universität Leipzig Betreuer: Herr Professor Dr. rer. medic. Holger Steinberg Beschluss über die Verleihung des Doktorgrades vom: 1 Inhaltsverzeichnis 1. Bibliografische Beschreibung…………………………………………………....…3 2. Einführung……………………………………………………………………………...4 2.1 Motivation und historischer Kontext…………………………….……………..…4 2.2 Schilders Biografie und Werk………………………………………….……........7 2.3 Methodik……………………………………………………………………..….....14 2.4 Bedeutung der Arbeit……………………………………………….….………....17 3. Publikationen………………………………………………………………..……..….19 3.1 Jahn M, Steinberg H (2019) Die Erstbeschreibung der Schilder-Krankheit. Paul Ferdinand Schilder und sein Ringen um die Abgrenzung einer neuen Entität. Nervenarzt 90:415-422 3.2 Jahn M, Steinberg H (2020) Die Schmerzasymbolie – um 1930 von Paul F. Schilder entdeckt und heute fast vergessen? Schmerz, Online First Article vom 25.02.2020 unter https://doi.org/10.1007/s00482-020-00447-z 4. Zusammenfassung der Arbeit……………………………………………..……...37 5. Literaturverzeichnis…………………………………………………………………42 6. Spezifizierung des eigenen wissenschaftlichen Beitrags……………………48 7. Erklärung über die eigenständige Abfassung der Arbeit…………………….49 8. -
Neurolinguistics
Neurolinguistics 1 What is neurolinguistics? Neurolinguistics studies the relation of language and communication to different aspects of brain function, i.e. it tries to explore how the brain understands and produces language and communication. This involves attempting to combine theory from neurology/neurophysiology (how the brain is structured and how it functions) with linguistic theory (how language is structured and how it functions). • "human language or communication (speech, hearing, reading, writing, or non-verbal modalities) related to any aspect of the brain or brain function" (Brain and Language: "Description") • The common problem area of relating aspects of language or communication to brain function in this dynamic formulation, is stated as a common question by Luria in "Basic problems in neurolinguistics": • "what are the real processes of formation of verbal communication and its comprehension, and what are the components of these processes and the conditions under which they take place" • (Luria, 1976, p.3) Interdisciplinary enterprise • linguistics,neuroanatomy, neurology, neurophysiology, philosophy, psychology, psychiatry, speech pathology and computer science, neurobiology, anthropology, chemistry, cognitive science and artificial intelligence. • Thus, the humanities, as well as medical, natural and social sciences, as well as technology are represented. Different views on the relation between brain and language • Localism tries to find locations or centers in the brain for different language functions. Associationism places language functions in the connections between different areas of the brain, making it possible to associate, for example, perceptions of different senses with words and/or “concepts”. • Dynamic localization of function assumes that functional systems of localized sub-functions perform language functions. Such systems are dynamic, so that they can be reorganized during language development or after a brain damage. -
Consensus Recommendations for Speech and Language Therapy Janet Baker,1,2 Caroline Barnett,3 Lesley Cavalli,4,5 Maria Dietrich,6 Lorna Dixon,7 Joseph R
BMJ Publishing Group Limited (BMJ) disclaims all liability and responsibility arising from any reliance Supplemental material placed on this supplemental material which has been supplied by the author(s) J Neurol Neurosurg Psychiatry BMJ Publishing Group Limited (BMJ) disclaims all liability and responsibility arising from any reliance Supplemental material placed on this supplemental material which has been supplied by the author(s) J Neurol Neurosurg Psychiatry General neurology REVIEW Management of Functional Communication, Swallowing, Cough, and Related Disorders: Consensus Recommendations for Speech and Language Therapy Janet Baker,1,2 Caroline Barnett,3 Lesley Cavalli,4,5 Maria Dietrich,6 Lorna Dixon,7 Joseph R. Duffy,8 Annie Elias,9 Diane E Fraser,10 Jennifer L. Freeburn,11 Catherine Gregory,2 Kirsty McKenzie,12 Nick Miller,13 Jo Patterson,14 Carole Roth,15 Nelson Roy,16,17 Jennifer Short,18 Rene L. Utianski,19,20 Miriam Van Mersbergen,21 Anne Vertigan,22,23 Alan Carson,24 Jon Stone,24 Laura McWhirter24 For numbered affiliations see ABSTRACT childhood development, in association with struc- end of article. Background Communication problems (e.g. dysphonia, tural anomalies, and as the result of neurological dysfluency, and language and articulation disorders), disease or injury. In contrast, there have been compar- Correspondence to swallowing disorders (dysphagia and globus), cough atively few intervention and outcome studies for indi- Dr Laura McWhirter, Centre for clinical brain sciences, and upper airway symptoms, resulting from Functional viduals with functional communication, swallowing, The University of Edinburgh, Neurological Disorder (FND), are commonly encountered by and cough disorders; while there is some evidence for Edinburgh, UK; speech and language professionals. -
Introduction
1 INTRODUCTION Dissociative disorder (conversion disorder), is symptoms and signs affecting voluntary motor or sensory function that cannot be explained by a neurological or general medical condition1.The reported prevalence in the neurology clinics of unexplained symptoms among new patients is very high (between 30 and 60%) and affects between 0.011% and 0.5% of the general population2. Previous prevalence studies found incidence rates of 22 and 11 newly diagnosed cases per 100,000 person-years, in Iceland and US respectively3(Gelder et al 2001). In Western societies the rate of Dissociative disorder (conversion disorder), is 1%to 3% in outpatient psychiatry clinics, whereas in non- Western societies it is about 10%4(Carson et al 2000). Dissociative disorder (conversion disorder), may develop at any time between early childhood and late old age, it is reported to be most common between 15 and 35 years of age. Dissociative disorder (conversion disorder), is more prevalent among females compared to males, with a ratio between 2:1 and 10:15(Nimnuan et al 2001). Dissociative disorder (conversion disorder), is also more prevalent in rural areas, in developing countries, among people of low socioeconomic classes, among undereducated people ,and among those with relatively low medical knowledge6(snijders et al 2004). In our study, we study about socio-demographic profile of the Dissociative disorder (conversion disorder) in our tertiary care centre. As far as presentation of dissociative disorders (conversion disorder) is concerned, previous studies reported that almost any physical symptom can be produced but most 2 common manifestations are those of similar to motor manifestations of neurological disease, for example: paraparesis, pseudoseizures and aphonia2. -
The Diagnosis and Management of Globus Pharyngeus: Our Perspective from the United Kingdom Petros D
CE: Alpana; MOO/264; Total nos of Pages: 4; MOO 264 The diagnosis and management of globus pharyngeus: our perspective from the United Kingdom Petros D. Karkosa and Janet A. Wilsonb aDepartment of Otolaryngology, Liverpool University Purpose of review Hospitals, Liverpool and bDepartment of Otolaryngology, The Freeman Hospital, To review recent literature on diagnostic and treatment options for globus pharyngeus. Newcastle University, Newcastle upon Tyne, UK Recent findings Correspondence to Mr Petros Karkos, MPhil, AFRCS, There are no controlled studies looking at the use of proton pump inhibitors specifically Specialist Registrar in Otolaryngology, 36 Hopkinsons for globus. The small volume of level I evidence has failed to demonstrate superiority Court, Walls Avenue, Chester, CH1 4LN, UK Tel: +44 1244340098; e-mail: [email protected] of proton pump inhibitors over placebo for treatment of laryngopharyngeal reflux symptoms (including globus). A recent pilot nonplacebo controlled study has shown Current Opinion in Otolaryngology & Head and Neck Surgery 2008, 16:1–4 promising results for treating laryngopharyngeal reflux symptoms with liquid alginate suspension. The role of cognitive behaviuoral therapy may hold hope for patients with refractory symptoms. A small randomized trial showed promising results for treating globus with speech therapy, but larger trials are required. There is no evidence for the use of antidepressants or anxiolytics. Summary After many decades of interest, the most popular organic theory that ‘A lump in the throat’ is reflux related is still challenged by lack of strong evidence for empiric antacid treatment of this symptom. Globus pharyngeus is a clinical diagnosis and not a diagnosis of exclusion and over investigating these patients is unnecessary. -
A Symptom-Based Approach to Treatment of Psychosis in Autism Spectrum Disorder* Victoria Bell†, Henry Dunne†, Tharun Zacharia, Katrina Brooker and Sukhi Shergill
BJPsych Open (2018) 4, 1–4. doi: 10.1192/bjo.2017.2 Short report A symptom-based approach to treatment of psychosis in autism spectrum disorder* Victoria Bell†, Henry Dunne†, Tharun Zacharia, Katrina Brooker and Sukhi Shergill Summary The optimal management of autism with psychosis remains Copyright and usage unclear. This report describes a 22-year-old man with autism and © The Royal College of Psychiatrists 2018. This is an Open Access psychosis who was referred to a tertiary-level specialist psych- article, distributed under the terms of the Creative Commons osis service, following a 6-year history of deterioration in mental Attribution-NonCommerical-NoDerivatives licence (http://crea- health starting around the time of sitting GCSE examinations and tivecommons.org/licenses/by-nc-nd/4.0/), which permits non- an episode of bullying at school. We describe the individualised commercial re-use, distribution, and reproduction in any symptom-based approach that was effective in his treatment. medium, provided the original work is unaltered and is properly cited. The written permission of Cambridge University Press Declaration of interest must be obtained for commercial re-use or in order to create a The authors declare no conflict of interest. derivative work. Knowledge of both autism spectrum disorder (ASD) and psychosis and investigate the co-occurrence of symptoms.9 The focus on clari- has developed within spectrum constructs. Despite the long history fying the diagnosis may be based on clinician preference or a way of of association between these disorders, there is often little clinician managing complexity, yet this may prove to be an obstacle in the awareness of how to assess and treat psychosis when it coexists with advancement of the formulation and treatment of the difficult ASD.