The Journal of Phytopharmacology 2020; 9(2): 149-154 Online at: www.phytopharmajournal.com

Systematic Review Review on secondary metabolites and therapeutics ISSN 2320-480X activities of Acacia nilotica used in African phytomedicine JPHYTO 2020; 9(2): 149-154 March- April Okri Frejus Hans Ohouko, Koffi Koudouvo, Jacques Tossou Dougnon, Arnaud Sas Soha, Jacques Adouko, Received: 19-03-2020 Accepted: 31-03-2020 Amegnona Agbonon, Messanvi Gbeassor ©2020, All rights reserved doi: 10.31254/phyto.2020.9213 ABSTRACT Today, more than 80% of the West African population use traditional medicine in case of illness. However, Okri Frejus Hans Ohouko (1). Research Unit in Applied Microbiology and several research studies are carried out in order to improve animal health, especially about antimicrobial Pharmacology of Natural Substances resistance and vaccine failures observed in farms. This study aimed to review findings about second (URMAPha), Laboratory of Research in Applied Biology (LARBA), University of metabolites and therapeutics activities of Acacia nilotica used in African phytomedicine. Information has Abomey Calavi, 01 BP 2009 Cotonou been searched on databases such as Agora, Hinari, Google Scholar, various journals, books and articles. (2). Centre of Training and Research in Medicinal (CERFOPLAM), Laboratory of Information capitalized are about traditional use of A. nilotica, antiviral, antifungal, antiparasitic, Physiology and Pharmacology of Natural antibacterial, antiplasmodial, anti-inflammatory and anti-hypertensive activities of the plant. These notions Substances, Faculty of Science, University of Lome, BP 1515 Lome, Togo constituted will help for better management of disease and other research perspectives like in vivo test of Acacia nilotica extracts on viral pathologies in Animal health. Koffi Koudouvo Centre of Training and Research in Medicinal Plant (CERFOPLAM), Laboratory of Keywords: Acacia nilotica, Review, Traditional use, Pharmacological activities. Physiology and Pharmacology of Natural Substances, Faculty of Science, University of Lome, BP 1515 Lome, Togo

Jacques Tossou Dougnon INTRODUCTION Research Unit in Applied Microbiology and Pharmacology of Natural Substances Ethnomedicine and the African veterinary pharmacopoeia, as an art and science stemming from African (URMAPha), Laboratory of Research in Applied Biology (LARBA), University of practice and cultures, are practiced and transmitted within society and their content remains a heritage Abomey Calavi, 01 BP 2009 Cotonou [1] either of a family or of a particular social group in the village or region . Today, more than 80% of the Arnaud Sas Soha West African population use traditional medicine in case of illness [2]. Health care therefore depends very Research Unit in Applied Microbiology and Pharmacology of Natural Substances much on medicinal and the local knowledge associated with them [3, 4]. Currently, numerous and (URMAPha), Laboratory of Research in Applied Biology (LARBA), University of rigorous scientific work are trying to develop this ancestral art of diagnosis and treatment of livestock Abomey Calavi, 01 BP 2009 Cotonou [5] diseases . However, in the African countries, domestic animals continue to pay a heavy price for various Jacques Adouko pathologies despite the import of veterinary drugs, which are at very uncompetitive costs [6]. Each year, Research Unit in Applied Microbiology and Pharmacology of Natural Substances the flock of poultry, small and large ruminants, pig, rabbits and other animal species are threatened. (URMAPha), Laboratory of Research in Applied Biology (LARBA), University of However, several research studies are carried out in order to improve animal health, especially about Abomey Calavi, 01 BP 2009 Cotonou [7] antimicrobial resistance and vaccine failures observed in farms. The mission of Akoegninou et al. listed Amegnona Agbonon 2807 plant species used in traditional Beninese medicine, including Acacia nilotic