3050 Spruce Street, Saint Louis, MO 63103 USA Tel: (800) 521-8956 (314) 771-5765 Fax: (800) 325-5052 (314) 771-5757 email: [email protected]

Product Information

Anti-FTH1 antibody produced in chicken, affinity isolated antibody Catalog Number GW20077F Formerly listed as GenWay Catalog Number 15-288-20077F, heavy chain Antibody. – Storage Temperature Store at 20 °C The product is a clear, colorless solution in phosphate buffered saline, pH 7.2, containing 0.02% sodium azide. Synonyms: Ferritin, heavy polypeptide 1, EC 1.16.3.1; Ferritin H subunit; Proliferation-inducing 15 protein Species Reactivity: Human Product Description Tested Applications: ELISA, WB Stores in a soluble, nontoxic, readily available form. Recommended Dilutions: Recommended starting dilution Important for iron homeostasis. Has activity. Iron for Western blot analysis is 1:500, for tissue or cell staining is taken up in the ferrous form and deposited as ferric 1:200. hydroxides after oxidation. This protein is the heavy subunit of the ferritin protein. Ferritin is the major intracellular iron Note: Optimal concentrations and conditions for each storage protein in and . It is application should be determined by the user. composed of 24 subunits of the heavy and light ferritin Precautions and Disclaimer chains. Variation in ferritin subunit composition may affect This product is for R&D use only, not for drug, household, or the rates of iron uptake and release in different tissues. A other uses. Due to the sodium azide content a material major function of ferritin is the storage of iron in a soluble safety data sheet (MSDS) for this product has been sent to and nontoxic state. Defects in ferritin proteins are associated the attention of the safety officer of your institution. Please with several neurodegenerative diseases. This protein has consult the Material Safety Data Sheet for information multiple pseudogenes. regarding hazards and safe handling practices. NCBI Accession number: NP_002023.2 Storage/Stability Swiss Prot Accession number: P02794 For continuous use, store at 2–8 °C for up to one week. For Gene Information: Human .. FTH1 (2495) extended storage, store in –20 °C freezer in working aliquots. Repeated freezing and thawing, or storage in Immunogen: Recombinant protein Ferritin, heavy polypep- “frostfree” freezers, is not recommended. If slight turbidity tide 1 occurs upon prolonged storage, clarify the solution by Immunogen Sequence: GI # 56682959, sequence 1 - 182 centrifugation before use. Working dilution samples should be discarded if not used within 12 hours. LPG,MAM12/09-1

Sigma brand products are sold through Sigma-Aldrich, Inc. Sigma-Aldrich, Inc. warrants that its products conform to the information contained in this and other Sigma-Aldrich publications. Purchaser must determine the suitability of the product(s) for their particular use. Additional terms and conditions may apply. Please see reverse side of the invoice or packing slip.