PSMB1 Antibody Cat. No.: 13-643
PSMB1 Antibody
Immunohistochemistry of paraffin-embedded rat brain Immunohistochemistry of paraffin-embedded human using PSMB1 antibody (13-643) at dilution of 1:100 (40x prostate cancer using PSMB1 antibody (13-643) at dilution lens). of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse Immunofluorescence analysis of MCF-7 cells using PSMB1 brain using PSMB1 antibody (13-643) at dilution of 1:100 antibody (13-643). Blue: DAPI for nuclear staining. (40x lens).
Specifications
HOST SPECIES: Rabbit
September 30, 2021 1 https://www.prosci-inc.com/psmb1-antibody-13-643.html SPECIES REACTIVITY: Human, Mouse, Rat
Recombinant fusion protein containing a sequence corresponding to amino acids 29-241 IMMUNOGEN: of human PSMB1 (NP_002784.1).
TESTED APPLICATIONS: IF, IHC, WB
WB: ,1:500 - 1:2000
APPLICATIONS: IHC: ,1:50 - 1:200
IF: ,1:50 - 1:200
POSITIVE CONTROL: 1) PC-3
2) Mouse brain
3) Rat spleen
PREDICTED MOLECULAR Observed: 25kDa WEIGHT:
Properties
PURIFICATION: Affinity purification
CLONALITY: Polyclonal
ISOTYPE: IgG
CONJUGATE: Unconjugated
PHYSICAL STATE: Liquid
BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles.
Additional Info
OFFICIAL SYMBOL: PSMB1
Proteasome subunit beta type-1, Macropain subunit C5, Multicatalytic endopeptidase ALTERNATE NAMES: complex subunit C5, Proteasome component C5, Proteasome gamma chain, PSMB1, PSC5
GENE ID: 5689
USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background and References
September 30, 2021 2 https://www.prosci-inc.com/psmb1-antibody-13-643.html The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An BACKGROUND: essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is tightly linked to the TBP (TATA-binding protein) gene in human and in mouse, and is transcribed in the opposite orientation in both species.
ANTIBODIES FOR RESEARCH USE ONLY.
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September 30, 2021 3 https://www.prosci-inc.com/psmb1-antibody-13-643.html