PSMB1 Antibody Cat. No.: 13-643

PSMB1 Antibody

Immunohistochemistry of paraffin-embedded rat brain Immunohistochemistry of paraffin-embedded human using PSMB1 antibody (13-643) at dilution of 1:100 (40x prostate using PSMB1 antibody (13-643) at dilution lens). of 1:100 (40x lens).

Immunohistochemistry of paraffin-embedded mouse Immunofluorescence analysis of MCF-7 cells using PSMB1 brain using PSMB1 antibody (13-643) at dilution of 1:100 antibody (13-643). Blue: DAPI for nuclear staining. (40x lens).

Specifications

HOST SPECIES: Rabbit

September 30, 2021 1 https://www.prosci-inc.com/psmb1-antibody-13-643.html SPECIES REACTIVITY: Human, Mouse, Rat

Recombinant fusion containing a sequence corresponding to amino acids 29-241 IMMUNOGEN: of human PSMB1 (NP_002784.1).

TESTED APPLICATIONS: IF, IHC, WB

WB: ,1:500 - 1:2000

APPLICATIONS: IHC: ,1:50 - 1:200

IF: ,1:50 - 1:200

POSITIVE CONTROL: 1) PC-3

2) Mouse brain

3) Rat spleen

PREDICTED MOLECULAR Observed: 25kDa WEIGHT:

Properties

PURIFICATION: Affinity purification

CLONALITY: Polyclonal

ISOTYPE: IgG

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles.

Additional Info

OFFICIAL SYMBOL: PSMB1

Proteasome subunit beta type-1, Macropain subunit C5, Multicatalytic endopeptidase ALTERNATE NAMES: complex subunit C5, component C5, Proteasome gamma chain, PSMB1, PSC5

GENE ID: 5689

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

September 30, 2021 2 https://www.prosci-inc.com/psmb1-antibody-13-643.html The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/-dependent process in a non-lysosomal pathway. An BACKGROUND: essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is tightly linked to the TBP (TATA-binding protein) gene in human and in mouse, and is transcribed in the opposite orientation in both species.

ANTIBODIES FOR RESEARCH USE ONLY.

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