International Journal of Environmental Research and Public Health Review Once Resin Composites and Dental Sealants Release Bisphenol-A, How Might This Affect Our Clinical Management?—A Systematic Review Anabela Baptista Paula 1,* , Debbie Toste 2, Alfredo Marinho 2, Inês Amaro 2, Carlos-Miguel Marto 1 , Ana Coelho 1 , Manuel Marques-Ferreira 3 and Eunice Carrilho 1 1 Institute of Integrated Clinical Practice, Institute for Clinical and Biomedical Research (iCBR), area of Environment Genetics and Oncobiology (CIMAGO), CNC.IBILI, Faculty of Medicine, University of Coimbra, 3000-075 Coimbra, Portugal;
[email protected] (C.-M.M.); anasofi
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[email protected] (I.A.) 3 Institute of Endodontics, Institute for Clinical and Biomedical Research (iCBR), area of Environment Genetics and Oncobiology (CIMAGO), CNC.IBILI, Faculty of Medicine, University of Coimbra, 3000-075 Coimbra, Portugal;
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[email protected]; Tel.: +351-934-262-687 Received: 26 March 2019; Accepted: 3 May 2019; Published: 9 May 2019 Abstract: (1) Background: Bisphenol A (BPA) based dental resins are commonly used in preventive and reparative dentistry. Since some monomers may remain unpolymerized in the application of dental resin, they dissolve in the saliva. (2) Methods: The literature search was carried out in Pubmed, Cochrane and Embase databases. Randomized controlled trials, cohort studies and case-control studies that evaluated BPA levels in human urine, saliva and/or blood were included.