Anti-NFKBIZ Polyclonal Antibody Cat: K002023P Summary:
【Product name】: Anti-NFKBIZ antibody 【Source】: Rabbit
【Isotype】: IgG 【Species reactivity】: Human, Mouse, Rat
【Swiss Prot】: Q9BYH8 【Gene ID】: 64332
【Calculated】: MW: 78kDa 【Observed】: MW: 88kDa
【Purification】: Affinity purification
【Tested applications】: WB
【Recommended dilution】: WB 1:500-2000.
【WB Positive sample】: THP-1, Mouse kidney, Rat kidney
【Subcellular location】: Nucleus.
【Immunogen】: Recombinant protein of human NFKBIZ.
【Storage】: Shipped at 4°C. Upon delivery aliquot and store at -20°C Background:
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is an organic cation transporter and plasma integral membrane protein containing eleven putative transmembrane domains as well as a nucleotide-binding site motif. Transport by this protein is at least partially ATP-dependent.This gene is a member of the ankyrin-repeat family and is induced by lipopolysaccharide (LPS). The C-terminal portion of the encoded product which contains the ankyrin repeats, shares high sequence similarity with the I kappa B family of proteins. The latter are known to play a role in inflammatory responses to LPS by their interaction with NF-B proteins through ankyrin-repeat domains. Studies in mouse indicate that this gene product is one of the nuclear I kappa B proteins and an activator of IL-6 production.
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Western blot analysis with NFKBIZ antibody diluted at 1:1000
Sales:[email protected] For research purposes only. Tech:[email protected] Please visit www.solarbio.com for a more product information