Anti-NFKBIZ Polyclonal Antibody Cat: K002023P Summary:

【Product name】: Anti-NFKBIZ antibody 【Source】: Rabbit

【Isotype】: IgG 【Species reactivity】: Human, Mouse, Rat

【Swiss Prot】: Q9BYH8 【 ID】: 64332

【Calculated】: MW: 78kDa 【Observed】: MW: 88kDa

【Purification】: Affinity purification

【Tested applications】: WB

【Recommended dilution】: WB 1:500-2000.

【WB Positive sample】: THP-1, Mouse kidney, Rat kidney

【Subcellular location】: Nucleus.

【Immunogen】: Recombinant of human NFKBIZ.

【Storage】: Shipped at 4°C. Upon delivery aliquot and store at -20°C Background:

Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is an organic cation transporter and plasma integral membrane protein containing eleven putative transmembrane domains as well as a nucleotide-binding site motif. Transport by this protein is at least partially ATP-dependent.This gene is a member of the -repeat family and is induced by (LPS). The C-terminal portion of the encoded product which contains the ankyrin repeats, shares high sequence similarity with the I kappa B family of . The latter are known to play a role in inflammatory responses to LPS by their interaction with NF-B proteins through ankyrin-repeat domains. Studies in mouse indicate that this gene product is one of the nuclear I kappa B proteins and an activator of IL-6 production.

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Western blot analysis with NFKBIZ antibody diluted at 1:1000

Sales:[email protected] For research purposes only. Tech:[email protected] Please visit www.solarbio.com for a more product information