Genetic Testing Common ICD-10-CM Codes

Listed below are the ICD-10-CM codes commonly received by LabCorp for genetic testing including cytogenetics, biochemical, and molecular genetics. For a more comprehensive list of codes commonly received for all LabCorp testing, please contact your local LabCorp representative. Code descriptions were taken from the official code set, issued by the US Department of Health and Human Services, as updated effective October 1, 2019 through September 30, 2020. Depending on the nature of your practice, this list may be a useful reference tool; however, it is not a complete list. Please refer to an ICD-10-CM manual for a complete listing. Responsibility for the provision of diagnosis code(s) is with the ordering physician. The ordering physician must always determine, for the specific date of service, the appropriate diagnosis code(s) based on the patient’s signs and symptoms. ICD-10-CM codes are required by third-party payers to support the medical necessity of the test(s) and/or profile(s) ordered. Physicians are asked to submit all medically appropriate ICD-10-CM codes when ordering laboratory testing.

LabCorp’s provision of this information as a customer service does not suggest and is not meant to suggest that any of these codes should or should not be used on any given occasion. LabCorp makes no recommendation regarding the use of any particular diagnosis code(s). Diagnosis information should be reflected in the patient’s medical record.

Diagnosis Diagnosis Code Diagnosis (sign or symptom) Code Diagnosis (sign or symptom) * ♀ Z3A.10 10 weeks gestation of pregnancy (maternity age 12-55) §♀ Z36.82 Encounter for antenatal screening for nuchal translucency * ♀ Z3A.11 11 weeks gestation of pregnancy (maternity age 12-55) (maternity age 12-55) * ♀ Z3A.12 12 weeks gestation of pregnancy (maternity age 12-55) §♀ Z36.8A Encounter for antenatal screening for other genetic defects * ♀ Z3A.13 13 weeks gestation of pregnancy (maternity age 12-55) (maternity age 12-55) ♀ Z3A.14 14 weeks gestation of pregnancy (maternity age 12-55) §♀ Z36.9 Encounter for antenatal screening, unspecified (maternity * age 12-55) * ♀ Z3A.15 15 weeks gestation of pregnancy (maternity age 12-55) ♀ Z3A.16 16 weeks gestation of pregnancy (maternity age 12-55) § Z31.41 Encounter for fertility testing * ¤ ♀ Z3A.17 17 weeks gestation of pregnancy (maternity age 12-55) §♀ Z01.419 Encounter for gynecological examination (general) (routine) * without abnormal findings (primary diagnosis only) ♀ Z3A.18 18 weeks gestation of pregnancy (maternity age 12-55) * § Z13.71 Encounter for nonprocreative screening for genetic disease ♀ Z3A.08 8 weeks gestation of pregnancy (maternity age 12-55) * carrier status ♀ Z3A.09 9 weeks gestation of pregnancy (maternity age 12-55) * v§♀ Z31.438 Encounter for other genetic testing of female for procreative n§♀ O28.5 Abnormal chromosomal and genetic finding on antenatal management screening of mother (maternity age 12-55) § Z13.79 Encounter for other screening for genetic and chromosomal ‡§ R79.9 Abnormal finding of blood chemistry, unspecified anomalies ‡§ R79.0 Abnormal level of blood mineral §♀ Z36.89 Encounter for other specified antenatal screening R74.8 Abnormal levels of other serum enzymes (maternity age 12-55) § R94.5 Abnormal results of liver function studies ♀ Z32.01 Encounter for pregnancy test, result positive (maternity age n§♀ O28.3 Abnormal ultrasonic finding on antenatal screening of 12-55) mother (maternal age 12-55) § Z31.5 Encounter for procreative genetic counseling p§ I82.409 Acute embolism and thrombosis of unspecified deep veins § Z13.1 Encounter for screening for diabetes mellitus of unspecified lower extremity § Z13.0 Encounter for screening for diseases of the blood and blood- §♀ N91.2 Amenorrhea, unspecified forming organs and certain disorders involving the immune § D64.9 Anemia, unspecified mechanism § M45.9 Ankylosing spondylitis of unspecified sites in spine § Z11.4 Encounter for screening for human immunodeficiency virus F41.9 Anxiety disorder, unspecified [HIV] L40.50 Arthropathic psoriasis, unspecified § Z11.3 Encounter for screening for infections with a predominantly l§ F84.0 Autistic disorder sexual mode of transmission q§ K90.0 Celiac disease SAMPLE§ Z13.220 Encounter for screening for lipoid disorders § M54.2 Cervicalgia ∆§ Z12.4 Encounter for screening for malignant neoplasm of cervix § R53.82 Chronic fatigue, unspecified § Z13.89 Encounter for screening for other disorder § C92.11 Chronic myeloid leukemia, BCR/ABL-positive, in remission § Z11.8 Encounter for screening for other infectious and parasitic § C92.10 Chronic myeloid leukemia, BCR/ABL-positive, not having diseases achieved remission § Z13.228 Encounter for screening for other metabolic disorders § D47.1 Chronic myeloproliferative disease § Z13.29 Encounter for screening for other suspected endocrine § D68.9 Coagulation defect, unspecified disorder § Z20.2 Contact with and (suspected) exposure to infections with a § Z11.59 Encounter for screening for other viral diseases predominantly sexual mode of transmission § Z11.1 Encounter for screening for respiratory tuberculosis § §Z20.828 Contact with and (suspected) exposure to other viral § Z13.9 Encounter for screening, unspecified communicable diseases §♀ Z34.01 Encounter for supervision of normal first pregnancy, first § E53.8 Deficiency of other specified B group vitamins trimester (maternity age 12-55) (primary diagnosis only) § R19.7 Diarrhea, unspecified §♀ Z34.02 Encounter for supervision of normal first pregnancy, second § M54.9 Dorsalgia, unspecified trimester (maternity age 12-55) (primary diagnosis only) ‡§ R79.82 Elevated C-reactive protein (CRP) §♀ Z34.00 Encounter for supervision of normal first pregnancy, R70.0 Elevated erythrocyte sedimentation rate unspecified trimester (maternity age 12-55) (primary § D72.829 Elevated white blood cell count, unspecified diagnosis only) § Z34.91 Encounter for supervision of normal pregnancy, unspecified, §♀ Z36.0 Encounter for antenatal screening for chromosomal ♀ anomalies (maternity age 12-55) first trimester (maternity age 12-55) (primary diagnosis only) Diagnosis Diagnosis Code Diagnosis (sign or symptom) Code Diagnosis (sign or symptom) §♀ Z34.92 Encounter for supervision of normal pregnancy, unspecified, § R71.8 Other abnormality of red blood cells second trimester (maternity age 12-55) (primary diagnosis only) u§ G89.29 Other chronic pain §♀ Z34.90 Encounter for supervision of normal pregnancy, unspecified, § R53.83 Other fatigue unspecified trimester (maternity age 12-55) (primary ²± Z79.899 Other long term (current) drug therapy diagnosis only) § R53.81 Other malaise §♀ Z34.81 Encounter for supervision of other normal pregnancy, first § D68.59 Other primary thrombophilia trimester (maternity age 12-55) (primary diagnosis only) I26.99 Other pulmonary embolism without acute cor pulmonale §♀ Z34.82 Encounter for supervision of other normal pregnancy, second ‡§ R79.89 Other specified abnormal findings of blood chemistry trimester (maternity age 12-55) (primary diagnosis only) R76.8 Other specified abnormal immunological findings in serum §♀ Z34.83 Encounter for supervision of other normal pregnancy, third § D89.89 Other specified disorders involving the immune mechanism, trimester (maternity age 12-55) (primary diagnosis only) not elsewhere classified §♀ Z34.80 Encounter for supervision of other normal pregnancy, M25.50 Pain in unspecified joint unspecified trimester (maternity age 12-55) (primary ²G Z86.718 Personal history of other venous thrombosis and embolism diagnosis only) Z76.89 Persons encountering health services in other specified C§ Z51.81 Encounter for therapeutic drug level monitoring circumstances v§♀ Z31.430 Encounter of female for testing for genetic disease carrier § M13.0 Polyarthritis, unspecified status for procreative management § D45 Polycythemia vera §♂ Z31.440 Encounter of male for testing for genetic disease carrier §♀ Z33.1 Pregnant state, incidental (maternity age 12-55) (secondary status for procreative management only diagnosis) § E34.9 Endocrine disorder, unspecified § E78.00 Pure hypercholesterolemia, unspecified § D47.3 Essential (hemorrhagic) thrombocytopenia § R76.0 Raised antibody titer t§ I10 Essential (primary) hypertension §♀ N96 Recurrent pregnancy loss ² Z84.81 Family history of carrier of genetic disease M06.9 Rheumatoid arthritis, unspecified ² Z83.2 Family history of diseases of the blood and blood-forming §♀ N91.1 Secondary amenorrhea organs and certain disorders involving the immune § D75.1 Secondary polycythemia mechanism n§♀ O09.521 Supervision of elderly multigravida, first trimester (maternity ² Z82.49 Family history of ischemic heart disease and other diseases age 12-55) of the circulatory system n§♀ O09.522 Supervision of elderly multigravida, second trimester ² Z80.3 Family history of malignant neoplasm of breast (maternity age 12-55) ² Z82.79 Family history of other congenital malformations, n§♀ O09.529 Supervision of elderly multigravida, unspecified trimester deformations and chromosomal abnormalities (maternity age 12-55) ² Z83.49 Family history of other endocrine, nutritional and metabolic n§♀ O09.511 Supervision of elderly primigravida, first trimester (maternity diseases age 12-55) § M79.7 Fibromyalgia n§♀ O09.512 Supervision of elderly primigravida, second trimester § K21.9 Gastro-esophageal reflux disease without esophagitis (maternity age 12-55) § R51 Headache n§♀ O09.519 Supervision of elderly primigravida, unspecified trimester § E83.119 Hemochromatosis, unspecified (maternity age 12-55) ì¸§ B20 Human immunodeficiency virus [HIV] disease n§♀ O09.91 Supervision of high risk pregnancy, unspecified, first § E78.5 Hyperlipidemia, unspecified trimester (maternity age 12-55) § E03.9 Hypothyroidism, unspecified n§♀ O09.92 Supervision of high risk pregnancy, unspecified, second § M06.4 Inflammatory polyarthropathy trimester (maternity age 12-55) D50.9 Iron deficiency anemia, unspecified n§♀ O09.90 Supervision of high risk pregnancy, unspecified, unspecified §♀ N92.6 Irregular menstruation, unspecifiedSAMPLEtrimester (maternity age 12-55) * ♀ Z3A.01 Less than 8 weeks gestation of pregnancy (maternity age n§♀ O09.891 Supervision of other high risk pregnancies, first trimester 12-55) (maternity age 12-55) § M54.5 Low back pain n§♀ O09.892 Supervision of other high risk pregnancies, second trimester nÀ§♀ O35.1XX0 Maternal care for (suspected) chromosomal abnormality in (maternity age 12-55) fetus, not applicable or unspecified (maternity age 12-55) n§♀ O09.32 Supervision of pregnancy with insufficient antenatal care, nÀ§♀ O35.2XX0 Maternal care for (suspected) hereditary disease in fetus, not second trimester (maternity age 12-55) applicable or unspecified (maternity age 12-55) § D69.6 Thrombocytopenia, unspecified nÀ§♀ O35.8XX0 Maternal care for other (suspected) fetal abnormality and t§ E11.9 Type 2 diabetes mellitus without complications damage, not applicable or unspecified (maternity age 12-55) § R10.9 Unspecified abdominal pain § E72.12 Methylenetetrahydrofolate reductase deficiency § R62.50 Unspecified lack of expected normal physiological § E78.2 Mixed hyperlipidemia development in childhood § M79.10 Myalgia, unspecified site § M19.90 Unspecified osteoarthritis, unspecified site R74.0 Nonspecific elevation of levels of transaminase and lactic q§ N39.0 Urinary tract infection, site not specified acid dehydrogenase [LDH] § D51.9 Vitamin B12 deficiency anemia, unspecified ¦§ E66.9 Obesity, unspecified § §E55.9 Vitamin D deficiency, unspecified § R89.8 Other abnormal findings in specimens from other organs, * ♀ Z3A.00 Weeks of gestation of pregnancy not specified (maternity systems and tissues age 12-55) Legend for Symbols * Code first complications of pregnancy, childbirth and the puerperium (O09-O09A) ♀ Female diagnosis only n Use additional code from category Z3A, Weeks of gestation, to identify the specific week of the pregnancy, if known

§ Excludes1 (mutually exclusive diagnosis code) notation applies (please refer to the ICD-10-CM manual) ‡ Use additional code to identify any retained foreign body, if applicable (Z18.-) p Code first venous embolism and thrombosis complicating: abortion, ectopic or molar pregnancy (O00-O07, O08.7) pregnancy, childbirth and the puerperium (O22.-, O87.-) l Use additional code to identify any associated medical condition and intellectual disabilities q Use additional code for associated disorders including: dermatitis herpetiformis (L13.0) gluten ataxia (G32.81) Code also exocrine pancreatic insufficiency (K86.81)

¤ Use additional code: for screening for human papillomavirus, if applicable (Z11.51) for screening vaginal pap smear, if applicable (Z12.72) to identify acquired absence of uterus, if applicable (Z9Ø.71-) v Use additional code for recurrent pregnancy loss, if applicable (N96, O26.2-) ∆ Use additional code to identify any family history of malignant neoplasm (Z80.-) Code also condition requiring care C Code also any long-term (current) drug therapy (Z79.-) ♂ Male diagnosis only t Use additional code to identify: exposure to environmental tobacco smoke (Z77.22) history of tobacco dependence (Z87.891) occupational exposure to environmental tobacco smoke (Z57.31) tobacco dependence (F17.-) tobacco use (Z72.0) ² Code also any follow-up examination (Z08-Z09) ì Use additional code to identify resistance to antimicrobial drugs (Z16.-)

¸ Code first Human immunodeficiency virus [HIV] disease complicating pregnancy, childbirth and the puerperium, if applicable (O98.7-) SAMPLE Use additional code(s) to identify all manifestations of HIV infection À Code also any associated maternal condition

¦ Code first obesity complicating pregnancy, childbirth and the puerperium, if applicable (O99.21-) Use additional code to identify body mass index (BNI), if known (Z68.-) u Code also related psychological factors associated with pain (F45.42) ± Code also any therapeutic drug level monitoring (Z51.81)

G Code first any follow-up examination after treatment (ZØ9) t Use additional code to identify control using: insulin Z79.4 oral antidiabetic drugs (Z79.84) oral hypoglycemic drugs (Z79.84) q Use additional code (B95-B97) to identify infectious agent