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Table 6.12: Deaths from poisoning, by sex and cause, Scotland, 2013

ICD code(s), cause of death and substance(s) 1 Both Males Females

ALL DEATHS FROM POISONING 823 583 240

ACCIDENTS 510 374 136 X40 - X49 Accidental poisoning by and exposure to …

X40 - Nonopioid , antipyretics and antirheumatics 6 4 2

X41 - Antiepileptic, -, antiparkinsonism and psychotropic drugs, not elsewhere classified , 2 1 1 Amitriptyline, , , , , || 1 0 1 Amitriptyline, || 1 0 1 Amitriptyline, Methadone || , , 1 1 0 Amitriptyline, Methadone, Benzodiazepine, , || Alcohol 1 0 1 Amitriptyline, Methadone, Diazepam || 1 0 1 Amitriptyline, Methadone, Diazepam, Dihydrocodeine, Alcohol || 1 0 1 Amitriptyline, Methadone, 1 0 1 Amitriptyline, Methadone, || , Alcohol 1 1 0 Amitriptyline, , Quinine, Morphine, Alcohol || Diazepam 1 0 1 || 2 2 0 Amphetamine, || 1 1 0 Amphetamine, Diazepam, Morphine, || Gabapentin, , Alcohol 1 1 0 Amphetamine, Methadone || Nordiazepam, Caffeine 1 1 0 Carbamazepine 1 1 0 , Methadone || Mirtazapine, Diazepam 1 0 1 , Codeine 1 1 0 Diazepam, Alcohol 1 0 1 Diazepam, Alcohol || 1 1 0 Diazepam, Alcohol || 1 1 0 , Diazepam, , Morphine, Codeine || Alcohol 1 0 1 , Methadone, Diazepam, Codeine, Morphine, Amphetamine, Mirtazapine, Alcohol || Paracetamol, Cannabis 1 1 0 Fluoxetine || Alcohol 1 0 1 Flupenthixol, Alcohol 1 1 0 Gabapentin || Methadone, Diazepam, , Tramadol, Pregabalin 1 1 0 Gabapentin, , Mirtazapine, Codeine, Chlorpheniramine, MDMA, Amphetamine || Amitriptyline, , Paracetamol, Cannabis1 1 0 Gabapentin, Methadone || Diazepam, Sertraline 1 0 1 Gabapentin, Methadone || Mirtazapine, Diazepam 1 1 0 Gabapentin, Methadone, Cocaine || Phenazepam, Mirtazapine, Cannabis, Alcohol 1 1 0 , , Quetiapine, Zopiclone 1 0 1 MDMA || 1 0 1 MDMA || Cocaine, Alcohol 1 1 0 MDMA || , Lignocaine, Alcohol 1 1 0 MDMA, Amphetamine, Cocaine || Diazepam 1 1 0 MDMA, Cocaine || Alcohol 2 2 0 MDMA, PMA, BZP, Cocaine || Methadone, Codeine, Paracetamol 1 0 1 MDMA, PMA, PMMA, BZP, Cocaine || Cannabis, Alcohol 1 1 0 Mephedrone, Alcohol || 1 1 0 Mirtazapine, Alcohol 1 0 1 Mirtazapine, Alcohol || 1 0 1 Mirtazapine, Olanzapine 1 1 0 Mirtazapine, Pregabalin, 1 0 1 PMA, Amphetamine || 1 1 0 PMA, BZP, Cocaine || 1 1 0 PMA, MDMA, BZP, Amphetamine || Cannabis 1 0 1 PMA, MDMA, BZP, TFMPP || Cocaine, Paracetamol, Cannabis, Alcohol 1 1 0 PMA, MDMA, Cocaine || Phenazepam, Diazepam, Cannabis, Alcohol 1 1 0 PMMA, Cocaine || Diazepam, , , Lignocaine, Alcohol 1 1 0 Phenazepam, Dihydrocodeine || Diazepam, Mirtazapine 1 1 0 Phenazepam, Etizolam, Morphine || 1 0 1 Pregabalin 1 1 0 , Mirtazapine, Alcohol 1 0 1 1 1 0 Zopiclone, Methadone, Benzodiazepine || 1 1 0 Zopiclone, Methadone, Benzodiazepine, Mirtazapine || Cocaine 1 1 0

X42 - and psychodysleptics [hallucinogens], not elsewhere classified AMT || Alcohol 1 1 0 AMT || Cannabis 1 1 0 AMT || Cocaine 1 1 0 API || 1 1 0 API, APB, Methylone || 1 0 1 || Diazepam, , Cannabis 1 1 0

Footnote 1) Where it appears, '||' distinguishes between substances which (i) were implicated in, or potentially contributed to, the cause of death; and (ii) were present but were not considered to have had any direct contribution to the death. Further information can be found in the detailed footnote at the end of the table.

© Crown Copyright 2014 ICD code(s), cause of death and substance(s) 1 Both Males Females

Buprenorphine, Cocaine || Diazepam, Phenazepam, Alcohol 1 1 0 Buprenorphine, Diazepam || Mirtazapine, Olanzapine, , Alcohol 1 1 0 Buprenorphine, Diazepam || Paracetamol, Codeine 1 1 0 Buprenorphine, Gabapentin, Phenazepam || Diazepam 1 1 0 Co-codamol 1 1 0 Co-codamol, Alcohol 1 1 0 Co-codamol, Propranolol 1 0 1 Cocaine, Amitriptyline, Gabapentin, Citalopram, Diazepam, Methadone, Heroin, Phenazepam || 1 0 1 Cocaine, Amphetamine || Morphine, Diazepam, Codeine, , Lignocaine 1 1 0 Cocaine, Benzoylecognine, Ecgonine methyl ester || , Fluoxetine, Paracetamol, Alcohol 1 0 1 Cocaine, Dihydrocodeine || Diazepam 1 1 0 Cocaine, Heroin || Paracetamol, Dihydrocodeine, Promethazine 1 1 0 Cocaine, Lignocaine || 1 1 0 Cocaine, Methadone || Diazepam 1 1 0 Cocaine, Methadone, Alcohol || Amitriptyline, Diazepam, Phenazepam 1 0 1 Cocaine, Morphine || Diazepam, Dihydrocodeine, Alcohol 1 1 0 Cocaine, Morphine, Codeine || Levamisole, Sildenafil 1 1 0 Codeine 3 2 1 Codeine || Paracetamol, , Alcohol 1 1 0 Codeine, Amitriptyline, Diazepam, Chlorpheniramine, Alcohol || Paracetamol, Citalopram 1 0 1 Codeine, Paracetamol 1 1 0 Codeine, Zopiclone, Alcohol || Paracetamol, Cannabis 1 1 0 Diamorphine, Alcohol || Cocaine 1 0 1 Diamorphine, Cocaine, Alcohol || 1 1 0 Dihydrocodeine || Amitriptyline, Diazepam, , Mirtazapine 1 0 1 Dihydrocodeine || Buprenorphine, Diazepam, Phenazepam, Alcohol 1 1 0 Dihydrocodeine || Chlorpromazine, Fluoxetine, Diazepam 1 1 0 Dihydrocodeine || Diazepam, Nordiazepam, Chlordiazepoxide, Phenazepam, Paracetamol, Propranolol 1 1 0 Dihydrocodeine || Diazepam, Phenazepam, Cannabis 1 1 0 Dihydrocodeine || Heroin, Methadone, Diazepam, Cannabis 1 0 1 Dihydrocodeine || Lignocaine 1 0 1 Dihydrocodeine || Phenazepam, Codeine, Sertraline, , Diazepam 1 1 0 Dihydrocodeine, Alcohol 1 1 0 Dihydrocodeine, Alcohol || Diazepam, Mirtazapine, Zopiclone 1 0 1 Dihydrocodeine, Codeine || , Paracetamol 1 1 0 Dihydrocodeine, Diazepam 1 1 0 Dihydrocodeine, Diazepam, Gabapentin, Alcohol || 1 1 0 Dihydrocodeine, Diazepam, Methadone, Gabapentin || Paracetamol, , Olanzapine 1 1 0 Dihydrocodeine, Methadone || Diazepam, Codeine, Cannabis 1 1 0 Dihydrocodeine, Methadone, Alcohol || Chlordiazepoxide, Diazepam 1 1 0 Dihydrocodeine, Methadone, Phenazepam || Diazepam, Amitriptyline, Citalopram, Alcohol 1 1 0 Dihydrocodeine, Pregabalin, Gabapentin, Citalopram 1 1 0 Dihydrocodeine, Promethazine 1 0 1 Dihydrocodeine, Tramadol, Zopiclone, Amitriptyline, Alcohol 1 1 0 Dihydrocodeine, Venlafaxine || Diazepam, Cannabis 1 1 0 , Tramadol, Amitriptyline || Alcohol 1 0 1 Heroin || Alcohol 1 1 0 Heroin || Amitriptyline, Citalopram, Diazepam 1 1 0 Heroin || Amitriptyline, Citalopram, Diazepam, Alcohol 1 1 0 Heroin || Amitriptyline, Diazepam, Phenazepam, Propranolol 1 1 0 Heroin || Amphetamine, Codeine, Etizolam, Phenazepam, Alcohol 1 0 1 Heroin || Codeine, Amitriptyline, Diazepam, Temazepam 1 1 0 Heroin || Codeine, Diazepam, Dihydrocodeine, Alcohol 1 1 0 Heroin || Codeine, Mirtazapine, Quetiapine, Phenazepam, Cannabis 1 1 0 Heroin || Diazepam 4 3 1 Heroin || Diazepam, Alcohol 2 2 0 Heroin || Diazepam, Buprenorphine 1 1 0 Heroin || Diazepam, Buprenorphine, Gabapentin 1 1 0 Heroin || Diazepam, Cannabis 1 1 0 Heroin || Diazepam, Cannabis, Alcohol 1 1 0 Heroin || Diazepam, Cannabis, Codeine 1 1 0 Heroin || Diazepam, Methadone 1 1 0 Heroin || Diazepam, Mirtazapine, Phenazepam, Alcohol 1 1 0 Heroin || Diazepam, Phenazepam, Alcohol 1 1 0 Heroin || Diazepam, Phenazepam, Codeine 1 1 0 Heroin || Diazepam, Phenazepam, Dihydrocodeine, Cannabis 1 1 0 Heroin || Diazepam, Phenazepam, , Alcohol 1 1 0 Heroin || Diazepam, Pregabalin, Tramadol 1 1 0 Heroin || Diazepam, Venlafaxine, Paracetamol, Cannabis, Alcohol 1 1 0 Heroin || Diazepam, Zopiclone, Pregabalin, Alcohol 1 1 0 Heroin || Dihydrocodeine, Cannabis 1 0 1 Heroin || Methadone, Diazepam, Cannabis, Codeine 1 1 0 Heroin || Mirtazapine, Alcohol 1 1 0

Footnote 1) Where it appears, '||' distinguishes between substances which (i) were implicated in, or potentially contributed to, the cause of death; and (ii) were present but were not considered to have had any direct contribution to the death. Further information can be found in the detailed footnote at the end of the table.

© Crown Copyright 2014 ICD code(s), cause of death and substance(s) 1 Both Males Females

Heroin || Mirtazapine, Diazepam, Buprenorphine 1 1 0 Heroin || Paracetamol, Diazepam, Alcohol 1 1 0 Heroin || Phenazepam 1 1 0 Heroin || Phenazepam, Diazepam 1 1 0 Heroin || Phenazepam, Diazepam, Cannabis, Alcohol 1 1 0 Heroin || Phenazepam, Dihydrocodeine 1 1 0 Heroin || Phenazepam, Paracetamol, Tramadol, Alcohol 1 1 0 Heroin || Sertraline, Etizolam 1 1 0 Heroin, Alcohol || 4 4 0 Heroin, Alcohol || Cannabis 1 1 0 Heroin, Alcohol || Cannabis, Mirtazapine, Phenazepam 1 0 1 Heroin, Alcohol || Cocaine, Codeine, Etizolam, Phenazepam, Diazepam, Amphetamine 1 1 0 Heroin, Alcohol || Codeine, Mirtazapine, Diazepam 1 1 0 Heroin, Alcohol || Diazepam 5 5 0 Heroin, Alcohol || Diazepam, Buprenorphine 1 1 0 Heroin, Alcohol || Diazepam, Cannabis 1 1 0 Heroin, Alcohol || Diazepam, Cannabis, Phenazepam 1 1 0 Heroin, Alcohol || Diazepam, Citalopram 1 1 0 Heroin, Alcohol || Dihydrocodeine, Fluoxetine, , Quetiapine 1 1 0 Heroin, Alcohol || , Citalopram 1 1 0 Heroin, Alcohol || Mirtazapine, Tramadol 1 1 0 Heroin, Amphetamine || Diazepam, Naproxen, Pregabalin, Cannabis, Alcohol 1 1 0 Heroin, Benzodiazepine, Alcohol || Paracetamol 1 1 0 Heroin, Buprenorphine, Alcohol || 1 1 0 Heroin, Buprenorphine, Alcohol || Lamotrigine, Paracetamol, Alcohol 1 1 0 Heroin, Buprenorphine, Methadone, Diazepam || Mirtazapine 1 1 0 Heroin, Cocaine || Diazepam 1 1 0 Heroin, Cocaine || Methadone, Amitriptyline, Diazepam 1 1 0 Heroin, Cocaine || Phenazepam 1 1 0 Heroin, Cocaine || Phenazepam, Cannabis 1 1 0 Heroin, Cocaine, Alcohol || Paroxetine, Cannabis 1 1 0 Heroin, Cocaine, Gabapentin, Diazepam || Paracetamol, Fluoxetine, Alcohol 1 1 0 Heroin, Diazepam || 2 2 0 Heroin, Diazepam || Alcohol 1 1 0 Heroin, Diazepam || Mirtazapine, Sertraline 1 1 0 Heroin, Diazepam, Alcohol || 1 1 0 Heroin, Diazepam, Amitriptyline || Mirtazapine, Phenazepam 1 1 0 Heroin, Dihydrocodeine || Buprenorphine, Promethazine, Cannabis 1 1 0 Heroin, Dihydrocodeine || Diazepam, Codeine, Paracetamol, Fluoxetine 1 1 0 Heroin, Dihydrocodeine, Alcohol || Diazepam 1 1 0 Heroin, Etizolam || Methadone, Mirtazapine, Buprenorphine 1 0 1 Heroin, Gabapentin || Citalopram 1 1 0 Heroin, Gabapentin || Diazepam, Alcohol 1 1 0 Heroin, Gabapentin, Diazepam || Lamotrigine, Paracetamol, Methadone 1 1 0 Heroin, Gabapentin, Phenazepam || Codeine, Cyclizine, Mirtazapine 1 0 1 Heroin, Methadone || Amitriptyline, Diazepam, Mirtazapine, Zopiclone, Pregabalin, Alcohol 1 0 1 Heroin, Methadone || Amitriptyline, Mirtazapine, Gabapentin 1 0 1 Heroin, Methadone || Diazepam, Cannabis, Paracetamol 1 0 1 Heroin, Methadone || Diazepam, Codeine 1 1 0 Heroin, Methadone || Diazepam, Mirtazapine, Paracetamol 1 1 0 Heroin, Methadone || Diazepam, Paracetamol, Alcohol 1 1 0 Heroin, Methadone || Diazepam, Promethazine, Paracetamol, Olanzapine 1 1 0 Heroin, Methadone || Gabapentin, Diazepam, Alcohol 1 1 0 Heroin, Methadone || Mirtazapine, Fluoxetine, Diazepam, Lorazepam, Promethazine 1 0 1 Heroin, Methadone || Phenazepam, Codeine, Alcohol 1 1 0 Heroin, Methadone, Alcohol || Diazepam 1 1 0 Heroin, Methadone, Alcohol || Propranolol, Cocaine 1 1 0 Heroin, Methadone, Cocaine || 1 1 0 Heroin, Methadone, Diazepam || Amitriptyline, Codeine 1 0 1 Heroin, Methadone, Tramadol, Diazepam, Amitriptyline || 1 1 0 Heroin, Methadone, Zopiclone || Diazepam, Alcohol 1 1 0 Heroin, Mirtazapine, Alcohol || Diazepam 1 1 0 Heroin, Morphine, 6MAM, Codeine, Zopiclone || 1 1 0 Heroin, Morphine, Alcohol || 1 1 0 Heroin, Morphine, Amitriptyline, Methadone || Diazepam, Mirtazapine, Alcohol 1 0 1 Heroin, Morphine, Codeine, Methadone, Diazepam, Cocaine, Co-dydramol, Paracetamol, Dihydrocodeine || 1 1 0 Heroin, Phenazepam || Diazepam, Buprenorphine, Alcohol 1 1 0 Heroin, Phenazepam, Methadone, Diazepam, Mirtazapine || Cannabis 1 0 1 Heroin, Tramadol, Dihydrocodeine, Amitriptyline || Gabapentin, Naproxen 1 0 1 Methadone 3 2 1 Methadone || 2 2 0 Methadone || Amphetamine, Diazepam, Phenazepam, Fluoxetine, Mirtazapine, Tramadol, Alcohol 1 0 1 Methadone || Cocaine, Diazepam, Cannabis 1 1 0

Footnote 1) Where it appears, '||' distinguishes between substances which (i) were implicated in, or potentially contributed to, the cause of death; and (ii) were present but were not considered to have had any direct contribution to the death. Further information can be found in the detailed footnote at the end of the table.

© Crown Copyright 2014 ICD code(s), cause of death and substance(s) 1 Both Males Females

Methadone || Codeine, Citalopram, Diazepam, Alcohol 1 1 0 Methadone || Codeine, Diazepam, Amitriptyline, Mirtazapine, Cannabis 1 1 0 Methadone || Diazepam 1 1 0 Methadone || Diazepam, Alcohol 2 2 0 Methadone || Diazepam, Buprenorphine 1 1 0 Methadone || Diazepam, Cannabis 2 2 0 Methadone || Diazepam, Citalopram, Mirtazapine, Gabapentin, Alcohol 1 1 0 Methadone || Diazepam, Codeine, Alcohol 1 1 0 Methadone || Diazepam, Dihydrocodeine, Gabapentin, Phenazepam, Cannabis 1 1 0 Methadone || Diazepam, Gabapentin, Alcohol 2 1 1 Methadone || Diazepam, Phenazepam 1 1 0 Methadone || Diazepam, Phenazepam, Cannabis 1 1 0 Methadone || Diazepam, Temazepam 1 1 0 Methadone || Diazepam, Trazodone, MDMA, Cannabis 1 1 0 Methadone || Etizolam 1 0 1 Methadone || Etizolam, Cannabis 1 1 0 Methadone || Etizolam, Chlorpromazine, Citalopram, Cannabis, Alcohol 1 1 0 Methadone || Fluoxetine, Diazepam, Morphine 1 1 0 Methadone || Mirtazapine, Diazepam, 1 0 1 Methadone || Morphine, Trimethoprim, Alcohol 1 1 0 Methadone || Phenazepam, Codeine 1 1 0 Methadone || Trazodone, Etizolam 1 1 0 Methadone, Alcohol || 3 2 1 Methadone, Alcohol || Cocaine, Diazepam, Mirtazapine, Chlordiazepoxide, Tramadol 1 1 0 Methadone, Alcohol || Codeine 1 1 0 Methadone, Alcohol || Diazepam 1 1 0 Methadone, Alcohol || Diazepam, Cannabis 1 1 0 Methadone, Alcohol || Olanzapine, Diazepam 1 1 0 Methadone, Alcohol || Olanzapine, Diazepam, Dihydrocodeine, Mirtazapine 1 1 0 Methadone, Amitriptyline || Diazepam, Dihydrocodeine 1 0 1 Methadone, Amphetamine, Diazepam || Zopiclone 1 1 0 Methadone, Amphetamine, Morphine || Diazepam, Gabapentin, Codeine, Dihydrocodeine 1 0 1 Methadone, Benzodiazepine || 1 1 0 Methadone, Benzodiazepine || Citalopram, Benzoylecgonine 1 1 0 Methadone, Benzodiazepine, Amitriptyline, Gabapentin || Lamotrigine, Paracetamol, Alcohol 1 0 1 Methadone, Benzodiazepine, Amitriptyline, Mirtazapine, Fluoxetine || Levamisole 1 0 1 Methadone, Benzodiazepine, Mirtazapine, Zopiclone || Gabapentin, Benzoylecognine 1 0 1 Methadone, Benzodiazepine, Pregabalin || Mirtazapine 1 0 1 Methadone, Benzodiazepine, Tramadol, Methiopropamine, MDPV, TFMPP || Mirtazapine 1 0 1 Methadone, Butane || Diazepam, Phenazepam, Trimethoprim 1 1 0 Methadone, Cocaine || 1 1 0 Methadone, Codeine || Diazepam, Fluoxetine, Paracetamol, Cannabis 1 1 0 Methadone, Cyclizine || Citalopram, Diazepam, , Alcohol 1 1 0 Methadone, Diazepam || 2 2 0 Methadone, Diazepam || Cannabis, Paroxetine 1 1 0 Methadone, Diazepam || Heroin, Morphine, 6MAM, Codeine, Gabapentin 1 1 0 Methadone, Diazepam || Paracetamol, Pregabalin 1 1 0 Methadone, Diazepam, Citalopram || Mirtazapine, Gabapentin 1 0 1 Methadone, Diazepam, Citalopram || Morphine, Alcohol 1 1 0 Methadone, Diazepam, Cocaine || 1 1 0 Methadone, Diazepam, Cocaine || Pregabalin, Cannabis 1 1 0 Methadone, Diazepam, Dihydrocodeine, Mirtazapine, Alcohol || 1 0 1 Methadone, Diazepam, Mirtazapine, Heroin, Phenazepam || Cannabis 1 1 0 Methadone, Diazepam, Pregabalin || Benzoylecognine 1 1 0 Methadone, Dihydrocodeine || Diazepam 1 1 0 Methadone, Dihydrocodeine || Diazepam, Temazepam, Codeine, Alcohol 1 1 0 Methadone, Dihydrocodeine, Diazepam || 1 0 1 Methadone, Dihydrocodeine, Diazepam, Amitriptyline, Gabapentin, || 1 0 1 Methadone, Dihydrocodeine, Diazepam, Phenazepam || Mirtazapine, Cocaine 1 1 0 Methadone, Dihydrocodeine, Mirtazapine, Phenazepam, Diazepam, Amphetamine || 1 0 1 Methadone, Etizolam, Diazepam, Dihydrocodeine || Cannabis 1 0 1 Methadone, Etizolam, Phenazepam, Amitriptyline, Codeine || Pregabalin 1 1 0 Methadone, Gabapentin || Benzoylecognine 1 1 0 Methadone, Gabapentin || Phenazepam, Diazepam, Promethazine 1 0 1 Methadone, Gabapentin, Alcohol || Diazepam 1 1 0 Methadone, Gabapentin, Alcohol || Diazepam, Paracetamol 1 1 0 Methadone, Gabapentin, Amitriptyline, Amphetamine, Diazepam || 1 1 0 Methadone, Gabapentin, Cyclizine || Mirtazapine 1 0 1 Methadone, Gabapentin, Diazepam || Phenazepam 1 1 0 Methadone, Heroin || Citalopram, Diazepam, Alcohol 1 0 1 Methadone, Heroin || Diazepam, Nortriptyline 1 1 0 Methadone, Heroin || Phenazepam, Diazepam 1 1 0 Methadone, Heroin, Diazepam, Phenazepam || Cocaine 1 1 0

Footnote 1) Where it appears, '||' distinguishes between substances which (i) were implicated in, or potentially contributed to, the cause of death; and (ii) were present but were not considered to have had any direct contribution to the death. Further information can be found in the detailed footnote at the end of the table.

© Crown Copyright 2014 ICD code(s), cause of death and substance(s) 1 Both Males Females

Methadone, Heroin, Gabapentin, Phenazepam || 1 0 1 Methadone, Heroin, Phenazepam, Gabapentin, Dihydrocodeine, Mirtazapine, Fluoxetine, Diazepam || Cannabis 1 1 0 Methadone, Methiopropamine, Promethazine, Diazepam, Dihydrocodeine || Alcohol 1 1 0 Methadone, Morphine, Alcohol || 1 0 1 Methadone, Morphine, Alcohol || Diazepam 1 1 0 Methadone, Morphine, Alcohol || Pregabalin, Phenazepam, Diazepam 1 1 0 Methadone, Morphine, Diazepam 1 1 0 Methadone, Morphine, Diazepam || Cannabis 1 1 0 Methadone, Morphine, Heroin || 1 0 1 Methadone, Morphine, Heroin || Alcohol 1 1 0 Methadone, Morphine, Phenazepam, Cocaine || 1 1 0 Methadone, Phenazepam 1 1 0 Methadone, Phenazepam || Amphetamine, Diazepam, Amitriptyline 1 1 0 Methadone, Phenazepam || Cannabis 1 1 0 Methadone, Phenazepam || Codeine 1 1 0 Methadone, Phenazepam, Cocaine || Diazepam, Cannabis 1 1 0 Methadone, Phenazepam, Diazepam || Quetiapine, Mirtazapine, Gabapentin, 1 1 0 Methadone, Pregabalin, Zopiclone || Diazepam, Alcohol 1 1 0 Methadone, Sertraline, Diazepam || 1 0 1 Methadone, Sertraline, Olanzapine || 1 1 0 Methadone, Tramadol || Diazepam 1 1 0 Methadone, Tramadol || Mirtazapine, Diazepam, Cannabis, Ibuprofen 1 0 1 Methadone, Trazodone, Mirtazapine, Pregabalin || Zopiclone, Diazepam, Alcohol 1 0 1 Methadone, Trazodone, Phenazepam || Cannabis 1 1 0 Methadone, Venlafaxine, Quetiapine || Diazepam, Trazodone 1 1 0 Methadone, Zopiclone, Benzodiazepine, Alcohol || 1 0 1 Methadone, Zopiclone, Mirtazapine, Diazepam || Venlafaxine, , Propranolol 1 0 1 Morphine || 1 1 0 Morphine || Amitriptyline, Alcohol 1 1 0 Morphine || Cocaine, Diazepam 1 1 0 Morphine || Codeine, Diazepam 1 1 0 Morphine || Diazepam, Fluoxetine, Mirtazapine 1 1 0 Morphine || Diazepam, Phenazepam, Paracetamol, Alcohol 1 0 1 Morphine || Paracetamol, Alcohol 1 1 0 Morphine || , Diazepam, Codeine 1 0 1 Morphine, Alcohol || Amitriptyline, Citalopram, Mirtazapine, Diazepam 1 1 0 Morphine, Amphetamine, Tramadol, Gabapentin, Fluoxetine, Diazepam, Dothiepin, Alcohol || Cannabis, Zopiclone 1 0 1 Morphine, Chlorpromazine, Gabapentin 1 0 1 Morphine, Cocaine, Alcohol || Diazepam, Cannabis 1 1 0 Morphine, Codeine 1 1 0 Morphine, Codeine || Paracetamol 1 1 0 Morphine, Codeine, Alcohol || Diazepam 1 1 0 Morphine, Codeine, Diazepam || Citalopram, Alcohol 1 1 0 Morphine, Codeine, Methadone || Cannabis 1 1 0 Morphine, Diazepam || 1 1 0 Morphine, Diazepam || Sertraline 1 1 0 Morphine, Diazepam, Gabapentin || Cannabis, 1 1 0 Morphine, Dihydrocodeine || 1 1 0 Morphine, Dihydrocodeine, Amitriptyline, Gabapentin || Diazepam, Paracetamol 1 0 1 Morphine, Dihydrocodeine, Diazepam || 1 1 0 Morphine, Dihydrocodeine, Diazepam || Cannabis, , Alcohol 1 1 0 Morphine, Heroin, Diazepam || 1 1 0 Morphine, Heroin, Dihydrocodeine, Phenazepam || Codeine, Gabapentin, Lamotrigine, Olanzapine, Promethazine, 1 1 0 Morphine,Venlafaxine, Methadone Trazodone, || Alcohol Cannabis 1 1 0 Morphine, Methadone || Diazepam, Cannabis, Paracetamol 1 0 1 Morphine, Methadone, Amitriptyline, Pregabalin || Dihydrocodeine, Benzodiazepine, Chlorpromazine, Alcohol 1 0 1 Morphine, Methadone, Dihydrocodeine, Diazepam, Phenazepam || Alcohol 1 1 0 Morphine, Methadone, Gabapentin || Diazepam, Cyclizine, Alcohol 1 1 0 Morphine, Oxycodone || 1 1 0 Morphine, Pregabalin 1 1 0 Morphine, Tramadol, Methadone || Diazepam, Amitriptyline, Promethazine, Mirtazapine 1 0 1 Morphine, Tramadol, Oxycodone, Diazepam, Alcohol || Fluoxetine 1 1 0 , Amitriptyline, Benzodiazepine, Gabapentin || Cocaine, Amphetamine, Mephedrone 1 1 0 Opiate, Diazepam, Alcohol || 1 1 0 Oxycodone, Amitriptyline || Pregabalin, Opiate, Alcohol 1 0 1 Oxycodone, , Etizolam, Diphenhydramine, MDMA, Lorazepam || 1 1 0 Tramadol 6 4 2 Tramadol || Dihydrocodeine, Diazepam, Mirtazapine 1 1 0 Tramadol, Alcohol 2 0 2 Tramadol, Alcohol || Diazepam, Chlorpromazine, Propranolol, Trazodone 1 1 0 Tramadol, Alcohol || Diazepam, Morphine, Codeine 1 1 0 Tramadol, Amitriptyline, Gabapentin, Morphine || Fluoxetine, Codeine, Diphenhydramine, Paracetamol, Cannabis, Diazepam 1 0 1 Tramadol, Diazepam, Nordiazepam, , Temazepam, Cocaine || Alcohol 1 1 0

Footnote 1) Where it appears, '||' distinguishes between substances which (i) were implicated in, or potentially contributed to, the cause of death; and (ii) were present but were not considered to have had any direct contribution to the death. Further information can be found in the detailed footnote at the end of the table.

© Crown Copyright 2014 ICD code(s), cause of death and substance(s) 1 Both Males Females

Tramadol, Dihydrocodeine || Cannabis 1 1 0 Tramadol, Gabapentin, Amitriptyline, Mirtazapine, Alcohol || 1 1 0 Tramadol, Methadone || Amitriptyline, Risperidone, , Pregabalin, Alcohol 1 0 1 Tramadol, Methadone, Morphine || Amitriptyline, Citalopram, Phenazepam, Promethazine, Diazepam, Cannabis 1 0 1 Tramadol, Steroid 1 1 0 Tramadol, Trazodone, Dihydrocodeine, Diazepam, Mirtazapine || Paracetamol 1 0 1 || Diamorphine, Methadone, Diazepam, Cocaine, Levamisole 1 1 0 || Heroin, Methadone, Alcohol 1 0 1 || Methadone, Heroin, Alcohol 1 1 0

X43 - Other drugs acting on the autonomic nervous system Aripiprazole, Alcohol 1 0 1 Procyclidine, Pregabalin, Zolpidem, Diazepam, Methadone, Chlorpromazine, Amitriptyline || Alcohol 1 0 1 Propranolol 2 1 1 Propranolol, Amitriptyline 1 0 1 Propranolol, Citalopram 1 0 1

X44 - Other and unspecified drugs, medicaments and biological substances 1 1 0 Lignocaine, Cocaine || 1 1 0 Theophylline 1 0 1 Unspecified drug 2 0 2

X45 - Alcohol Alcohol 77 54 23 Alcohol || 3 1 2 Alcohol || Chlordiazepoxide, Diazepam 1 1 0 Alcohol || Citalopram 1 0 1 1 1 0 Propane, Butane, Isobutane, Alcohol || 1 1 0

X46 - Organic solvents and halogenated hydrocarbons and their vapours Lighter fuel, Propane, Butane || Amitriptyline, Phenazepam, Paracetamol, Morphine 1 0 1

X47 - Other gases and vapours Butane || 1 1 0 Butane, Isobutane, Methadone 1 1 0 Butane, Lighter fuel || Phenazepam, Cannabis 1 1 0

X49 - Other and unspecified chemicals and noxious substances Asbestos 11 10 1

INTENTIONAL SELF-HARM 116 80 36 X60 -X69 Intentional self-poisoning by and exposure to …

X60 - Nonopioid analgesics, antipyretics and antirheumatics || 1 1 0 Aspirin, Propranolol 1 1 0 Paracetamol 2 2 0 Paracetamol, Chlorpromazine, Phenazepam, Codeine, Diazepam, Alcohol || Citalopram 1 1 0 Paracetamol, Codeine 1 0 1 Paracetamol, Codeine, Paroxetine, Alcohol 1 0 1

X61 - Antiepileptic, sedative-hypnotic, antiparkinsonism and psychotropic drugs, not elsewhere classified Amisulpride 1 1 0 Amitriptyline || Fluoxetine, Alcohol 1 1 0 Amitriptyline, Alcohol 1 1 0 Amitriptyline, Chlorpheniramine 1 1 0 Amitriptyline, Cocaine, Alcohol || 1 1 0 Amitriptyline, Fluoxetine, Alcohol || 1 0 1 Amitriptyline, Zopiclone, Dihydrocodeine, Alcohol 1 1 0 Citalopram, Diazepam, Morphine, Codeine || Alcohol 1 1 0 Citalopram, Venlafaxine, Propranolol || 1 1 0 Clomipramine, Fluoxetine, Risperidone 1 1 0 Dothiepin 1 1 0 , Tramadol, Co-codamol 1 1 0 Duloxetine, Mirtazapine, Risperidone, Alcohol 1 1 0 Fluoxetine, Clomipramine, Olanzapine 1 0 1 Gamma hydroxybutyrate || Carbamazepine, Alcohol 1 1 0 Lithium || 1 1 0 Mirtazapine, Sertraline, Dihydrocodeine, Paracetamol, Diazepam || 1 0 1 Olanzapine 1 1 0

Footnote 1) Where it appears, '||' distinguishes between substances which (i) were implicated in, or potentially contributed to, the cause of death; and (ii) were present but were not considered to have had any direct contribution to the death. Further information can be found in the detailed footnote at the end of the table.

© Crown Copyright 2014 ICD code(s), cause of death and substance(s) 1 Both Males Females

Olanzapine || Alcohol 1 1 0 Pentobarbitone || Alcohol 1 0 1 Quetiapine || 1 0 1 Quetiapine || Diazepam, Fluoxetine, Alcohol 1 0 1 Sertraline 1 0 1 Sertraline, Alcohol 1 1 0 Venlafaxine 1 1 0 Venlafaxine, Quetiapine 1 0 1

X62 - Narcotics and psychodysleptics [hallucinogens], not elsewhere classified Co-proxamol, Dihydrocodeine || Mirtazapine, Benzodiazepine, Alcohol 1 0 1 Codeine, Benzodiazepine || Mirtazapine, Gabapentin, Propranolol, Paracetamol, Naproxen 1 1 0 Codeine, Citalopram 1 0 1 Codeine, Diazepam, Paracetamol || 1 1 0 Codeine, Quetiapine 1 0 1 Dihydrocodeine 2 0 2 Dihydrocodeine || Diazepam, Methadone, Codeine 1 1 0 Dihydrocodeine, Amitriptyline, Dipipanone, Cyclizine 1 1 0 Dihydrocodeine, Codeine 1 0 1 Dihydrocodeine, Dipipanone, Zopiclone, Cyclizine 1 1 0 Dihydrocodeine, Tramadol || Diazepam, Cannabis, Cocaine, Citalopram 1 1 0 Heroin, Alcohol || Diazepam 1 1 0 Heroin, Methadone, Phenazepam, Diazepam, Temazepam || Mirtazapine, Cannabis 1 1 0 Methadone || 1 0 1 Methadone || Codeine, Dihydrocodeine, Paracetamol, Diazepam, Fluoxetine 1 0 1 Methadone || Diazepam, Cannabis, 1 1 0 Methadone || Diazepam, Mirtazapine 1 1 0 Methadone || Diazepam, Mirtazapine, Quetiapine 1 1 0 Methadone, Alcohol || 1 1 0 Methadone, Alcohol || Phenazepam, Mirtazapine, Tramadol, Cannabis 1 1 0 Methadone, Amitriptyline, Diazepam, Alcohol || Gabapentin, Cannabis 1 1 0 Methadone, Diazepam || 1 1 0 Methadone, Diazepam, Amitriptyline, Dihydrocodeine || Fluoxetine, Cannabis, Alcohol 1 1 0 Methadone, Fluoxetine, Amitriptyline || Diazepam 1 0 1 Methadone, Mirtazapine || Heroin, Diazepam, Amphetamine 1 1 0 Methadone, Phenazepam || 1 1 0 Methadone, Phenazepam || Quetiapine, Diazepam 1 1 0 Morphine || Alcohol 1 1 0 Morphine || Sertraline, Mirtazapine, Cannabis, Alcohol 1 1 0 Morphine, Codeine, Amitriptyline, Chlordiazepoxide, Paracetamol, Tramadol, Zopiclone 1 1 0 Morphine, Diazepam || Paroxetine, Alcohol 1 0 1 Morphine, Gabapentin, Alcohol || Amitriptyline 1 0 1 Morphine, Gabapentin, Tramadol, Amitriptyline, Dihydrocodeine, Diazepam, Codeine || 1 0 1 Morphine, Methadone || Diazepam, Olanzapine 1 0 1 Oxycodone 2 1 1 Oxycodone || Lignocaine, Zopiclone, 1 1 0 Tramadol 2 1 1 Tramadol || 2 1 1 Tramadol, Amitriptyline 1 1 0 Tramadol, Clomipramine 1 0 1 Tramadol, Co-codamol 1 1 0 Tramadol, Co-proxamol 1 1 0 Tramadol, Imipramine, Chlorpromazine || 1 1 0 Tramadol, Pregabalin 1 1 0 Tramadol, Quetiapine 1 0 1

X63 - Other drugs acting on the autonomic nervous system Propranolol 2 1 1 Propranolol || 1 0 1 Propranolol || Cocaine, Carbamazepine, Diazepam, Citalopram, Alcohol 1 1 0 Propranolol || Gabapentin, Diazepam, Alcohol 1 1 0 Propranolol, Alcohol 1 0 1 Propranolol, Amitriptyline, Promethazine || , Alcohol 1 0 1 Propranolol, Citalopram, Sertraline, Alcohol || 1 1 0 Propranolol, Cocaine 1 1 0

X64 - Other and unspecified drugs, medicaments and biological substances Amlodipine, Chlorpromazine, Mirtazapine, Tramadol, Diazepam, Alcohol || Paracetamol 1 1 0 Chloroquine 1 1 0 Chloroquine || 1 0 1 Helium 6 5 1 , Alcohol || Mirtazapine 1 1 0 Unspecified drug 1 1 0

Footnote 1) Where it appears, '||' distinguishes between substances which (i) were implicated in, or potentially contributed to, the cause of death; and (ii) were present but were not considered to have had any direct contribution to the death. Further information can be found in the detailed footnote at the end of the table.

© Crown Copyright 2014 ICD code(s), cause of death and substance(s) 1 Both Males Females

Warfarin 1 1 0

X66 - Organic solvents and halogenated hydrocarbons and their vapours Ethylene glycol 1 1 0 Hydrocarbon || Alcohol 1 0 1

X67 - Other gases and vapours Butane, Propane 1 1 0 Carbon monoxide 4 4 0 Carbon monoxide || 1 1 0 Carbon monoxide || Alcohol 1 1 0 Carbon monoxide, Zopiclone 1 1 0 Nitrogen 1 1 0

X69 - Other and unspecified chemicals and noxious substances Cyanide, 2 1 1

EVENTS OF UNDETERMINED INTENT 134 85 49 Y10 - Y19 Poisoning by and exposure to …

Y10 - Nonopioid analgesics, antipyretics and antirheumatics Paracetamol 7 3 4 Paracetamol || 1 1 0 Paracetamol || Unspecified drug 1 1 0 Paracetamol, Unspecified drug 1 0 1

Y11 - Antiepileptic, sedative-hypnotic, antiparkinsonism and psychotropic drugs, not elsewhere classified Amitriptyline || 1 1 0 Amitriptyline, Alcohol || Co-codamol 1 1 0 Amitriptyline, Cocaine, Gabapentin, Alcohol || 1 1 0 Amitriptyline, Morphine || 1 0 1 Amphetamine, BZP, Tramadol || Mirtazapine, Citalopram 1 1 0 , 1 1 0 Caffeine || Amitriptyline, Paracetamol, Cannabis, Alcohol 1 0 1 Citalopram 1 0 1 Citalopram, , Alcohol 1 1 0 Clomipramine, Methadone, Olanzapine, Gabapentin || Amitriptyline, Diazepam, Cannabis 1 0 1 1 1 0 Clozapine || Procyclidine, Fluoxetine, Amisulpride, Alcohol 1 0 1 Clozapine, Alcohol || 1 1 0 Dothiepin 1 0 1 Dothiepin, Gabapentin, Tramadol, Phenazepam, Fentanyl 1 0 1 Gabapentin, Amitriptyline, Tramadol 1 0 1 Gabapentin, Heroin, Tramadol, Dihydrocodeine || Diazepam, Alcohol 1 1 0 Gabapentin, Tramadol 1 1 0 Gabapentin, Tramadol, Amitriptyline, Buprenorphine || Zopiclone, Diazepam, Alcohol 1 1 0 Lithium 1 0 1 MDMA, Diazepam, Gabapentin 1 1 0 Olanzapine 1 1 0 PMA, PMMA, MDMA, BZP || Alcohol 1 1 0 Promethazine, Tramadol, Dihydrocodeine, Amitriptyline 1 0 1 Temazepam 1 1 0

Y12 - Narcotics and psychodysleptics [hallucinogens], not elsewhere classified Buprenorphine, Diazepam, Cocaine, Alcohol || 1 1 0 Co-codamol || Fluoxetine, Paracetamol 1 0 1 Co-codamol, Alcohol 1 0 1 Co-codamol, Alcohol || Amitriptyline 1 1 0 Co-codamol, Citalopram, Alcohol 1 0 1 Co-codamol, Codeine, Paracetamol || 1 1 0 Cocaine || Diazepam, Quetiapine, Alcohol 1 1 0 Cocaine, Alcohol || 1 1 0 Cocaine, Morphine, Diazepam || Alcohol 1 1 0 Dihydrocodeine 2 2 0 Dihydrocodeine || Diazepam, Fluoxetine 1 1 0 Dihydrocodeine, Alcohol || 1 1 0 Dihydrocodeine, Alcohol || Paracetamol 1 0 1 Dihydrocodeine, Diazepam 1 1 0 Dihydrocodeine, Diazepam, Amitriptyline || Morphine, Cannabis 1 1 0 Dihydrocodeine, Heroin, Alcohol || Diazepam 1 1 0 Dihydrocodeine, Methadone || Gabapentin, Mirtazapine, Metoclopramide, Diazepam, Cannabis, Alcohol 1 1 0 Dihydrocodeine, Methadone, Gabapentin, Diazepam || 1 0 1

Footnote 1) Where it appears, '||' distinguishes between substances which (i) were implicated in, or potentially contributed to, the cause of death; and (ii) were present but were not considered to have had any direct contribution to the death. Further information can be found in the detailed footnote at the end of the table.

© Crown Copyright 2014 ICD code(s), cause of death and substance(s) 1 Both Males Females

Fentanyl || 1 0 1 Heroin || Amphetamine, MDMA 1 1 0 Heroin, Alcohol || 1 0 1 Heroin, Alcohol || Diazepam, Paracetamol 1 1 0 Heroin, Alcohol || Tramadol, Paracetamol 1 1 0 Heroin, Alcohol || Valproic acid, Mirtazapine 1 1 0 Heroin, Benzodiazepine || Methadone, Alcohol 1 1 0 Heroin, Diazepam, Gabapentin, Alcohol || 1 1 0 Heroin, Dihydrocodeine, Phenazepam || Codeine, Diazepam, Alcohol 1 1 0 Heroin, Methadone || Diazepam 1 1 0 Heroin, Methadone, Alcohol || 1 1 0 Heroin, Methadone, Diazepam, Chlordiazepoxide, Alcohol || 1 1 0 Heroin, Mirtazapine || Amlodipine, Diazepam, Temazepam 1 0 1 Heroin, Phenazepam, Diazepam || 1 1 0 Heroin, Tramadol, Alcohol || Amitriptyline, Chlordiazepoxide 1 0 1 Methadone || Carbamazepine, Diazepam, Venlafaxine 1 1 0 Methadone || Diazepam, Citalopram, Zopiclone, Lithium, Quetiapine, Alcohol 1 1 0 Methadone || Diazepam, Fluoxetine 1 0 1 Methadone || Diazepam, Gabapentin 1 1 0 Methadone || Diazepam, Gabapentin, Amitriptyline 1 0 1 Methadone || Diazepam, Mirtazapine 2 1 1 Methadone || Diazepam, Procyclidine, Cannabis 1 1 0 Methadone, Amitriptyline, Diazepam, Alcohol || 1 1 0 Methadone, Amphetamine, Alcohol || Diazepam, Tramadol 1 1 0 Methadone, Amphetamine, Amitriptyline, Diazepam, Alcohol || Paracetamol 1 1 0 Methadone, Benzodiazepine, Alcohol 1 0 1 Methadone, Diazepam, Dihydrocodeine || Citalopram, Olanzapine, Cannabis 1 1 0 Methadone, Diazepam, Heroin || EDDP 1 1 0 Methadone, Dihydrocodeine || Diazepam 1 1 0 Methadone, Dihydrocodeine || Diazepam, Gabapentin, Diphenhydramine, Ibuprofen, Paracetamol 1 0 1 Methadone, Dihydrocodeine || Diazepam, Mirtazapine, Amitriptyline, Zopiclone, Fentanyl, Phenazepam 1 0 1 Methadone, Dihydrocodeine, Diazepam, Amitriptyline, Methylethcathinone, Gabapentin || 1 1 0 Methadone, Heroin, Gabapentin || Diazepam, Mirtazapine, Olanzapine, Alcohol 1 1 0 Methadone, Morphine || 1 1 0 Methadone, Morphine, Codeine, Diazepam, Dihydrocodeine || Olanzapine, Mirtazapine, Cannabis 1 1 0 Methadone, Morphine, Diazepam || Codeine, Lamotrigine, , Trazodone 1 1 0 Methadone, Morphine, Diazepam, MDMA || Alcohol 1 1 0 Methadone, Morphine, Etizolam, Gabapentin || 1 1 0 Methadone, Morphine, Sertraline || Pregabalin, Diazepam 1 0 1 Methadone, Tramadol, Alcohol || Phenytoin, Diazepam, Chlordiazepoxide 1 1 0 Methadone, Tramadol, Venlafaxine || Diazepam 1 0 1 Morphine || Citalopram, Amitriptyline 1 1 0 Morphine || Venlafaxine, Diazepam, Dihydrocodeine, Buprenorphine, Non-steroidal anti-inflammatory drugs 1 0 1 Morphine, Alcohol || Diazepam, Dihydrocodeine, Caffeine, Noscapine, Papaverine 1 1 0 Morphine, Amitriptyline || Alcohol 1 0 1 Morphine, Diazepam || Cannabis, Dihydrocodeine 1 1 0 Morphine, Diazepam || Zopiclone 1 1 0 Morphine, Diazepam, Alcohol || 1 1 0 Morphine, Dihydrocodeine, Amitriptyline, Gabapentin || 1 0 1 Opiate 1 0 1 Oxycodone 1 0 1 Oxycodone, Alcohol 1 1 0 Tramadol || Alcohol 1 1 0 Tramadol || Citalopram, Paracetamol, Codeine 1 1 0 Tramadol || Clonazepam 1 1 0 Tramadol || Gabapentin, Mirtazapine, Olanzapine, 1 1 0 Tramadol || Phenazepam, Quetiapine, Mirtazapine 1 0 1 Tramadol || Quetiapine, Morphine, Ibuprofen, Lamotrigine 1 1 0 Tramadol, Alcohol 1 0 1 Tramadol, Diazepam || 1 1 0 Tramadol, MDMA, Morphine || 1 1 0

Y13 - Other drugs acting on the autonomic nervous system , Alcohol 1 0 1 Propranolol 2 1 1

Y14 - Other and unspecified drugs, medicaments and biological substances Chloroquine || Nitrazepam, Promethazine, Paracetamol 1 1 0 Helium 1 0 1 Unspecified drug 6 2 4 Zopiclone, Diazepam, Codeine, Olanzapine, Dihydrocodeine || 1 0 1

Footnote 1) Where it appears, '||' distinguishes between substances which (i) were implicated in, or potentially contributed to, the cause of death; and (ii) were present but were not considered to have had any direct contribution to the death. Further information can be found in the detailed footnote at the end of the table.

© Crown Copyright 2014 ICD code(s), cause of death and substance(s) 1 Both Males Females

Y16 - Organic solvents and halogenated hydrocarbons and their vapours Mineral oil, Carbon tetrachloride 1 0 1 Unspecified solvent 1 1 0

Y17 - Other gases and vapours Butane, Lighter fuel, Isobutane, Propane || Diazepam 1 1 0 Butane, Methadone || 1 1 0 Carbon monoxide 1 1 0

Y19 - Other and unspecified chemicals and noxious substances Detergent 1 0 1

MENTAL DISORDERS 42 35 7 F11 - F19 Mental and behavioural disorders due to psychoactive substance use

F11 - || Buprenorphine 1 1 0

F12 - || Cannabis, Alcohol 1 1 0

F15 - Other stimulants, including caffeine || Amphetamine 1 1 0

F19 - Multiple drug use and use of other psychoactive substances Fentanyl, Etizolam, Diazepam, MDPV || 1 1 0 Methadone, Diazepam, Morphine, Buprenorphine, Phenazepam || 1 1 0 Methadone, Morphine, Diazepam, Phenazepam || Codeine, Paracetamol, Mirtazapine, Cannabis 1 1 0 Steroid 1 1 0 Unspecified drug 8 7 1 Unspecified drug || 3 3 0 Unspecified drug || Methadone 1 1 0 || Clomipramine, Diazepam, Mpa, , Alcohol 1 1 0 || Diazepam, Cannabis, Methadone, Morphine 1 0 1 || Diazepam, Fentanyl, Alcohol 1 1 0 || Diazepam, Methadone 1 0 1 || Diazepam, Methadone, Alcohol 1 1 0 || Diazepam, Methadone, EDDP, Cannabis, Alcohol 1 1 0 || Diazepam, Morphine 1 1 0 || Diphenhydramine, Mirtazapine, Methadone, Pregabalin 1 0 1 || Gabapentin, Methadone, Citalopram, Alcohol 1 1 0 || Lignocaine, Methadone, Diazepam, Cannabis, Alcohol 1 1 0 || Methadone, Diazepam, Mirtazapine, Cannabis, Alcohol 1 0 1 || Methadone, Diazepam, Quetiapine, Gabapentin, Cannabis, Alcohol 1 1 0 || Methadone, EDDP, Mirtazapine, Phenazepam, Benzoylecognine, Amphetamine, Alcohol 1 1 0 || Methadone, Mirtazapine, Gabapentin, Diazepam, Alcohol 1 1 0 || Methadone, Morphine, Heroin, Amitriptyline, Cannabis 1 1 0 || Methadone, Nitrazepam, Diazepam 1 1 0 || Methadone, Phenazepam, Venlafaxine, Olanzapine 1 1 0 || Methadone, Sertraline, Lignocaine, Diazepam 1 0 1 || Mirtazapine, Diazepam 1 1 0 || Phenazepam, Morphine, Diazepam, Paracetamol 1 1 0 || Propranolol, Olanzapine, Fluoxetine, Pregabalin, Diazepam, Alcohol 1 1 0 || Tramadol, Diazepam, Pregabalin, Alcohol 1 0 1 || Tramadol, Venlafaxine, Buprenorphine, Alcohol 1 1 0

COMPLICATIONS OF MEDICAL AND SURGICAL CARE 21 9 12 Y40 - Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use

Y40 - Systemic antibiotics Flucloxacillin 1 1 0

Y41 - Other systemic anti-infectives and antiparasites Metronidazole 1 1 0

Y42 - Hormones and their synthetic substitutes and antagonists, not elsewhere classified Steroid 2 0 2

Y44 - Agents primarily affecting blood constituents 3 1 2

Footnote 1) Where it appears, '||' distinguishes between substances which (i) were implicated in, or potentially contributed to, the cause of death; and (ii) were present but were not considered to have had any direct contribution to the death. Further information can be found in the detailed footnote at the end of the table.

© Crown Copyright 2014 ICD code(s), cause of death and substance(s) 1 Both Males Females

Heparin 2 0 2 Warfarin 2 2 0

Y45 - Analgesics, antipyretics and anti-inflammatory drugs Co-codamol 1 1 0 Ibuprofen 1 0 1 Non-steroidal anti-inflammatory drugs 2 0 2

Y48 - Anaesthetics and therapeutic gases Anaesthetic 1 0 1

Y49 - Psychotropic drugs, not elsewhere classified Lithium 1 1 0

Y52 - Agents primarily affecting the cardiovascular system Statin 1 1 0

Y57 - Other and unspecified drugs and medicaments Unspecified drug 3 1 2

Footnote 1) Where it appears, '||' distinguishes between substances which (i) were implicated in, or potentially contributed to, the cause of death; and (ii) were present but were not considered to have had any direct contribution to the death. Further information can be found in the detailed footnote at the end of the table. In most cases of deaths involving or resulting from the abuse of controlled substances, pathologists supply National Records of Scotland (NRS) with further information, using form ME4, including details of the drugs or solvents which were found in the body. Pathologists are asked to distinguish between the drugs or solvents: (i) which, the pathologists believe, were implicated in, or which potentially contributed to, the cause of death; and (ii) which were present, but which were not considered to have had any direct contribution to this death. In this table, the symbol '||' is used to distinguish between the substances which were mentioned under (i) and (ii): - anything listed before '||' was, a pathologist believed, implicated in, or potentially contributed to, the cause of death; - anything listed after '||' was present but not considered to have had any direct contribution to the death. The '||' appears at the start of the list of substances in cases where the pathologist indicated that all the substances were present but not considered to have had any direct contribution to the death. The '||' appears at the end of the list of substances in cases where the pathologist believed that all the substances were implicated in, or potentially contributed, to the cause of death. There is no '||' if NRS did not receive an 'ME4' form for example deaths not involving, or resulting from the abuse of, controlled substances). Further information about the 'ME4' form can be found in 'Drug-related Deaths in Scotland', which is available on the NRS website. Please note that NRS may edit slightly a list of substance names, if it contains any 'duplicates'. For example: (a) 'Opiate' should be removed if specific (e.g. Morphine) were also reported; (b) 'Benzodiazepine' should be removed if specific (e.g. Diazepam) were also reported (c) 'Ecstasy' should be removed if specific ecstasy-type drugs (e.g. MDMA) were also reported. Where '||' appears, NRS edits the parts of the list before and after '||' separately, so the list as a whole could contain 'duplicates'.

© Crown Copyright 2014