Chemically Active Rheological Modifiers for the Improved Clinical Use of Cyanoacrylates
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Dispensing Solutions for Cyanoacrylate Adhesives White
Dispensing Solutions for Cyanoacrylate Adhesives Contents How Cyanoacrylates Work .......................................................................3 Advantages of CAs ...................................................................................4 CA Dispensing Challenges .......................................................................4 Best Practices for Dispensing CAs .....................................................5-12 Best Systems for Dispensing CAs ....................................................13-14 Useful Resources ...................................................................................15 Introduction Cyanoacrylate adhesives, also known as CAs or cyanos, are highly effective at bonding many types of materials together in assembly processes. Often referred to as super glues, they exhibit high bond strength and fast cure times that help manufacturers speed production processes for higher throughput yields. This makes them an ideal choice for assembling products in a variety of industries, including automotive, electronics, life sciences, defense, and consumer goods. Though beneficial, these moisture-cure adhesives can be a challenge, especially when your assembly process requires precise, repeatable dispensing. This paper outlines proper handling methods and dispensing solutions for successful CA dispensing. Find out how to minimize material waste by more than 60% while also minimizing operator exposure to the adhesive. Speed your production processes while producing higher quality parts with -
N-Butyl Cyanoacrylate Synthesis. a New Quality Step Using Microwaves
Molecules 2014, 19, 6220-6227; doi:10.3390/molecules19056220 OPEN ACCESS molecules ISSN 1420-3049 www.mdpi.com/journal/molecules Article n-Butyl Cyanoacrylate Synthesis. A New Quality Step Using Microwaves Yaquelin Ramos Carriles 1,*, Rubén Álvarez Brito 1, Ricardo Martínez Sánchez 2, Elayma Sánchez Acevedo 1, Paola Rodríguez Domínguez 1 and Wolf-Dieter Mueller 3 1 Chemistry-Physics Department, Faculty of Chemistry, University of Havana, Zapata and G, Vedado, Havana 10400, Cuba; E-Mails: [email protected] (R.Á.B.); [email protected] (E.S.A.); [email protected] (P.R.D.) 2 Polymers Laboratory, IMRE, University of Havana, Zapata and G, Vedado, Havana 10400, Cuba; E-Mail: [email protected] 3 Charité-Universitaetsmedizin Berlin, Assmannshauser Str.4-6, Berlin 14197, Germany; E-Mail: [email protected] * Author to whom correspondence should be addressed; E-Mail: [email protected]; Tel.: +537-878-0684; Fax: +537-837-5774. Received: 4 April 2014; in revised form: 5 May 2014 / Accepted: 13 May 2014 / Published: 15 May 2014 Abstract: Alkyl cyanoacrylates are interesting products for use in industry because of their properties enabling them to stick together a wide range of substrates. n-Butyl cyanoacrylate is one of the most successfully used tissue adhesives in the field of medicine because it exhibits bacteriostatic and haemostatic characteristics, in addition to its adhesive properties. At present, its synthesis is performed with good yields via Knoevenagel condensation using conventional sources of heating, but this requires a long processing time. The aim of this work was to look for a new way of synthesising n-butyl cyanoacrylate using microwave irradiation as the source of heating. -
Enhanced Friction and Adhesion with Biologically Inspired Fiber Arrays
Enhanced Friction and Adhesion with Biologically Inspired Fiber Arrays Carmel Majidi Electrical Engineering and Computer Sciences University of California at Berkeley Technical Report No. UCB/EECS-2007-55 http://www.eecs.berkeley.edu/Pubs/TechRpts/2007/EECS-2007-55.html May 15, 2007 Copyright © 2007, by the author(s). All rights reserved. Permission to make digital or hard copies of all or part of this work for personal or classroom use is granted without fee provided that copies are not made or distributed for profit or commercial advantage and that copies bear this notice and the full citation on the first page. To copy otherwise, to republish, to post on servers or to redistribute to lists, requires prior specific permission. Enhanced Friction and Adhesion with Biologically Inspired Fiber Arrays by Carmel Shamim Majidi B.S. (Cornell University) 2001 M.S. (University of California, Berkeley) 2004 A thesis submitted in partial satisfaction of the requirements for the degree of Doctor of Philosophy in Engineering - Electrical Engineering and Computer Science in the GRADUATE DIVISION of the UNIVERSITY OF CALIFORNIA, BERKELEY Committee in charge: Professor Ronald S. Fearing, Chair Professor Kyriakos Komvopoulos Professor Ali Javey Spring 2007 The thesis of Carmel Shamim Majidi is approved. Chair Date Date Date University of California, Berkeley Spring 2007 Enhanced Friction and Adhesion with Biologically Inspired Fiber Arrays Copyright c 2007 by Carmel Shamim Majidi Abstract Enhanced Friction and Adhesion with Biologically Inspired Fiber Arrays by Carmel Shamim Majidi Doctor of Philosophy in Engineering - Electrical Engineering and Computer Science University of California, Berkeley Professor Ronald S. Fearing, Chair Controlling surface forces through nano/microstructure represents an important advance- ment in tribology. -
Gluture Topical Tissue Adhesive Other Means of Identification Synonyms Gluture® * Topical Vet Adhesive Recommended Use Veterinary Adhesive
SAFETY DATA SHEET 1. Identification Product identifier GLUture Topical Tissue Adhesive Other means of identification Synonyms GLUture® * Topical Vet Adhesive Recommended use Veterinary Adhesive. Recommended restrictions Not for human use Manufacturer/Importer/Supplier/Distributor information Company Name (US) Zoetis Inc. 10 Sylvan Way Parsippany, New Jersey 07054 (USA) Rocky Mountain Poison 1-866-531-8896 and Drug Center Product Support/Technical 1-800-366-5288 Services Emergency telephone CHEMTREC (24 hours): 1-800-424-9300 numbers International CHEMTREC (24 hours): +1-703-527-3887 Company Name (EU) Zoetis Belgium S.A. Mercuriusstraat 20 1930 Zaventem Belgium Emergency telephone International CHEMTREC (24 hours): +1-703-527-3887 number Contact E-Mail [email protected] 2. Hazard(s) identification Physical hazards Flammable liquids Category 4 Health hazards Skin corrosion/irritation Category 2 Serious eye damage/eye irritation Category 2A Sensitization, skin Category 1 Environmental hazards Not classified. OSHA defined hazards Not classified. Label elements Signal word Warning Hazard statement Combustible liquid. Causes skin irritation. May cause an allergic skin reaction. Causes serious eye irritation. Precautionary statement Prevention Keep away from flames and hot surfaces-No smoking. Avoid breathing mist or vapor. Wash thoroughly after handling. Contaminated work clothing must not be allowed out of the workplace. Wear protective gloves/eye protection/face protection. Response If on skin: Wash with plenty of water. If skin irritation or rash occurs: Get medical advice/attention. If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice/attention. Take off contaminated clothing and wash before reuse. -
Nano-Hairs: Dry Adhesives
Geckos: From climbing up walls, trees to being upside-down. The gecko has mastered the skill of climbing and sticking to any surface at any angle. The ability to scurry up and down surfaces at blistering pace is what has allowed the gecko to escape predators and catch its own prey. The most crucial ability to the survival of this species. But how are these animals able to defy gravity? The answer; Nanohairs. Nano-Hairs: These hairs on the pads of their toes are called setae, and they pos- ses about two million of them.(lerch) But how do microscopic sized hairs allow a gecko to not only stick but climb up walls? These hairs are spread out when pushed against a surface. This drastically in- creases the surface area a gecko has on a surface. A gecko can simply relax the force it has against the surface causing less hairs to be spread out leading to a smaller surface area and van der waals forces, allowing it to lift its foot off. Dry Adhesives: Comparing a gecko to our adhesive technologies, there is clear superiorities that the gecko’s feet posses. Suc- tions adhesives are expensive and costly, while ones that rely on chemical bonds are sticky and permanent. Using inspiration from geckos nanohairs though, these flaws have been eliminated. Creating synthetic setae with nanotechnology, adhesives have been able to be made that have incredible adhesive capacities, howev- er like the gecko are not sticky nor are permanent. . -
Safety, Efficacy, and Outcomes of N-Butyl Cyanoacrylate Glue Injection Through the Endoscopic Or Radiologic Route for Variceal G
Journal of Clinical Medicine Review Safety, Efficacy, and Outcomes of N-Butyl Cyanoacrylate Glue Injection through the Endoscopic or Radiologic Route for Variceal Gastrointestinal Bleeding: A Systematic Review and Meta-Analysis Olivier Chevallier 1 ,Kévin Guillen 1 , Pierre-Olivier Comby 2, Thomas Mouillot 3 , Nicolas Falvo 1, Marc Bardou 3, Marco Midulla 1, Ludwig-Serge Aho-Glélé 4 and Romaric Loffroy 1,* 1 Department of Vascular and Interventional Radiology, Image-Guided Therapy Center, ImViA Laboratory-EA 7535, François-Mitterrand University Hospital, 14 Rue Paul Gaffarel, BP 77908, 21079 Dijon, France; [email protected] (O.C.); [email protected] (K.G.); [email protected] (N.F.); [email protected] (M.M.) 2 Department of Neuroradiology and Emergency Radiology, François-Mitterrand University Hospital, 14 Rue Paul Gaffarel, BP 77908, 21079 Dijon, France; [email protected] 3 Department of Gastroenterology and Hepatology, François-Mitterrand University Hospital, 14 Rue Paul Gaffarel, BP 77908, 21079 Dijon, France; [email protected] (T.M.); [email protected] (M.B.) 4 Department of Biostatistics and Epidemiology, François-Mitterrand University Hospital, 14 Rue Paul, Citation: Chevallier, O.; Guillen, K.; Gaffarel, BP 77908, 21079 Dijon, France; [email protected] Comby, P.-O.; Mouillot, T.; Falvo, N.; * Correspondence: [email protected]; Tel.: +33-380-293-358 Bardou, M.; Midulla, M.; Aho-Glélé, L.-S.; Loffroy, R. Safety, Efficacy, and Abstract: We performed a systematic review and meta-analysis of published studies to assess the Outcomes of N-Butyl Cyanoacrylate efficacy, safety, and outcomes of N-butyl cyanoacrylate (NBCA) injection for the treatment of variceal Glue Injection through the gastrointestinal bleeding (GIB). -
Modeling Fabrication and Testing of Artificial Gecko Adhesion Using Multi Layer Fbrillar Structure
International Journal of Latest Technology in Engineering, Management & Applied Science (IJLTEMAS) Volume VI, Issue VIIIS, August 2017 | ISSN 2278-2540 Modeling Fabrication and Testing of Artificial Gecko Adhesion using Multi Layer Fbrillar Structure Ameya P. Nijasure, Priam V. Pillai Department of Mechanical Engineering, Pillai Collage of Engineering, New Panvel, Raigad, India. Abstract- The idea of designing a micro level artificial gecko deform independently, which makes sure that each fiber adhesive structure is inspired from ability of geckos to climb any reaches deeper in case of rough surface to achieve clean surface. Gecko can climb any rough or smooth surface because contact [8]. The key parameter that plays important role in of its hierarchical structure present on feet which functions as a gecko adhesion are pattern periodicity of a synthetic setae, smart adhesive [1]. The key parameter that affects gecko hierarchical structure, length, diameter, angle, size, stiffness of adhesion are pattern periodicity of a synthetic setae, hierarchical end tips and flexibility of a base. structure, length, diameter, angle, size, stiffness of end tips and flexibility of a base [2]. The design and fabrication of number of Each five-toed foot of the gecko has about 500,000 foot- single and multi-level hierarchical pattern were performed. CO2 hairs called setae a uniformly distributed array each about LASER cutting machine having power of 60 W is used to 110µm in length and 4.2µm diameter. Further it is divided in manufacture moulds. The mould is fabricated from methyl to spatulae a thin stalk with triangular shape tiny end of 0.2µm methacrylate sheets of different thickness 3 mm to 10 mm. -
Hummel Polymer Library
Hummel Polymer Library Index Number Compound Name Index Number Compound Name 1 Pinewood pyrolyzate 27 Pine resin, fresh 2 Urea-formaldehyde resin 28 Poly(1,4-butylene pyrolyzate terephthalate) 3 Pinewood pyrolyzate 29 Polyester, terephthalic 4 Poly(acrylonitrile) acid 5 Poly(acrylonitrile:butadien 30 Polyester, terephthalic e:styrene) acid 6 Poly(fumaronitrile:styrene) 31 Poly(acrylonitrile:vinyliden 7 Polyamide-6 e chloride),3:1 8 Poly(ester urethane), MBI 32 Poly(1,4-butylene 9 Poly(ester urethane), MBI terephthalate) 10 Alkyd, sunflower oil acids, 33 Poly(acrylonitrile:methyl PAnh,MAnh,pentaerythrito methacrylate) l 34 Epoxy resin, Bisphenol A 11 Phenol resol + epichlorohydrin 12 Poly(isobutene) + ester 35 Methacrylate oligomer 13 Phenol resol, cured 36 Carboxymethylcellulose, 14 Poly(2,6-dimethyl-1,4- Na salt phenylene 37 Poly(vinylidene fluoride) ether)+polystyrene 38 Poly(vinyl chloride) 15 Polyester, tere- & 39 Alkyd, 26% linseed oil + isophthalic acids PAnh 16 Polyester, tere- & 40 Alkyd, 49% linseed oil + isophthalic acids PAnh 17 Polyester, tere- & 41 Alkyd, 26% linseed isophthalic acids oil+PAnh + melamine 18 Polyester, terephthalic resin acid 42 Alkyd, 49% linseed 19 Polyester, terephthalic oil+PAnh + melamine acid resin 20 Polyester, tere- & 43 Alkyd, 40% castor oil + isophthalic acids PAnh 21 Polyurethane, linear, 44 Alkyd, 68% castor oil + aliphatic PAnh 22 Polyester, tere- & 45 Alkyd, 68%castor isophthalic acids oil+PAnh + melamine 23 Polyester, tere- & resin isophthalic acids 46 Epoxy resin, Bisphenol A 24 Polyester, tere- & + epichlorohydrin isophthalic acids 47 Epoxy + melamine resins 25 Polyester, tere- & 1:1 isophthalic acids 48 Poly(vinyl butyral) 26 Polyester, tere- & 49 Epoxy resin + poly(vinyl isophthalic acids butyral) Hummel Polymer Library, page 1 of 29 Index Number Compound Name Index Number Compound Name 50 Melamine resin, etherified methacrylate:acrylonitrile) 51 Alkyd, aliphatic 92 Poly(methyl 52 Melamine-formaldehyde methacrylate:acrylonitrile) cond. -
Properties, Principles, and Parameters of the Gecko Adhesive System
Preprint: Autumn, K. 2006. Properties, principles, and parameters of the gecko adhesive system. In Smith, A. and J. Callow, Biological Adhesives. SpringerKellar Verlag. Autumn The Gecko Adhesive System 1 of 39 Do not copy or distribute without permission of the author ([email protected]). Copyright (c) 2005 Kellar Autumn. Properties, Principles, and Parameters of the Gecko Adhesive System Kellar Autumn Department of Biology Lewis & Clark College Portland, OR 97219-7899 [email protected] 10156 words + 130 references. 6 figures, 2 tables. “The designers of the future will have smarter adhesives that do considerably more than just stick” –Fakley 2001 1. Summary Gecko toe pads are sticky because they feature an extraordinary hierarchy of structure that functions as a smart adhesive. Gecko toe pads (Russell 1975) operate under perhaps the most severe conditions of any adhesives application. Geckos are capable of attaching and detaching their adhesive toes in milliseconds (Autumn et al. 2005 (in press)) while running with seeming reckless abandon on vertical and inverted surfaces, a challenge no conventional adhesive is capable of meeting. Structurally, the adhesive on gecko toes differs dramatically from that of conventional adhesives. Conventional pressure sensitive adhesives (PSAs) such as those used in adhesive tapes are fabricated from materials that are sufficiently soft and sticky to flow and make intimate and continuous surface contact (Pocius 2002). Because they are soft and sticky, PSAs also tend to degrade, foul, self- adhere, and attach accidentally to inappropriate surfaces. Gecko toes typically bear a series of scansors covered with uniform microarrays of hair-like setae formed from !- keratin (Russell 1986; Wainwright et al. -
New Type Cyanoacrylate Medical Adhesive And
(19) *EP003335738B1* (11) EP 3 335 738 B1 (12) EUROPEAN PATENT SPECIFICATION (45) Date of publication and mention (51) Int Cl.: of the grant of the patent: A61L 24/06 (2006.01) A61L 24/04 (2006.01) (2006.01) (2006.01) 06.11.2019 Bulletin 2019/45 A61L 15/24 C09J 133/14 A61L 24/00 (2006.01) (21) Application number: 15900803.6 (86) International application number: (22) Date of filing: 19.08.2015 PCT/CN2015/087551 (87) International publication number: WO 2017/024606 (16.02.2017 Gazette 2017/07) (54) NEW TYPE CYANOACRYLATE MEDICAL ADHESIVE AND PREPARATION METHOD AND USE THEREOF NEUARTIGER MEDIZINISCHER CYANACRYLATKLEBSTOFF UND HERSTELLUNGSVERFAHREN UND VERWENDUNG DAVON ADHÉSIF MÉDICAL DE CYANOACRYLATE DE NOUVEAU TYPE, ET PROCÉDÉ DE PRÉPARATION ET UTILISATION DE CE DERNIER (84) Designated Contracting States: • YU, Shufang AL AT BE BG CH CY CZ DE DK EE ES FI FR GB Beijing 100176 (CN) GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO • WANG, Pengfei PL PT RO RS SE SI SK SM TR Beijing 100176 (CN) • SHAO, Jie (30) Priority: 11.08.2015 CN 201510489872 Beijing 100176 (CN) (43) Date of publication of application: (74) Representative: LLR 20.06.2018 Bulletin 2018/25 11, boulevard de Sébastopol 75001 Paris (FR) (73) Proprietor: Shen, Wei Beijing 100176 (CN) (56) References cited: WO-A1-02/09785 WO-A1-2015/059644 (72) Inventors: CN-A- 101 495 377 CN-A- 103 083 718 • SHEN, Wei CN-A- 104 710 953 US-A1- 2002 037 310 Beijing 100176 (CN) US-A1- 2002 037 310 US-A1- 2003 082 116 • XU, Jinghai Beijing 100176 (CN) Note: Within nine months of the publication of the mention of the grant of the European patent in the European Patent Bulletin, any person may give notice to the European Patent Office of opposition to that patent, in accordance with the Implementing Regulations. -
Nanoapplications – from Geckos to Human Health Correspondence To
Nanoapplications – From geckos to human health Correspondence to: Simone Lerch Simone Lerch nspm ltd, Luzernerstr. 36 nspm ltd, Meggen, Switzerland 6045 Meggen Switzerland [email protected] Abstract Nanotechnology, the manipulation of matter on a bundles as synthetic setae (see Figure 1C and D), molecular scale, is all around us in our everyday and possesses adhesive capacities nearly four lives. Chocolate, non-dairy creamer, and sunscreen times higher than that of gecko feet. It even sticks are examples of consumer products with a high to Teflon. content of nanoparticles. Nanotechnology holds great potential for environmental applications like What is nanotechnology? wastewater treatment and nanobionic engineering Nanotechnology is generally defined as the manipu- of plants. Due to their unique and adaptable lation of matter on a molecular scale, typically in the properties for targeted therapeutic payload delivery, − range of nanometres (1 nm = 10 9 m). Nanomatter nanoparticles are also emerging as promising is typically smaller than a cell, but bigger than a tools for innovative pharmaceutical treatment. small molecule (see Figure 2). The European Union Nevertheless, licensing regulations specifically for (EU) defines nanomaterials as ‘natural, incidental nanomaterials are lacking, and the long-term or manufactured material containing particles, in effects of nanoparticles on both the environment an unbound state or as an aggregate or as an and human health need to be further clarified. agglomerate and where, for 50% or more of -
Gecko-Inspired Carbon Nanotube-Based Self-Cleaning
NANO LETTERS 2008 Gecko-Inspired Carbon Nanotube-Based Vol. 8, No. 3 Self-Cleaning Adhesives 822-825 Sunny Sethi,† Liehui Ge,† Lijie Ci,‡ P. M. Ajayan,‡ and Ali Dhinojwala*,† Department of Polymer Science, The UniVersity of Akron, Akron, Ohio 44325, Department of Materials Science and Engineering, Rensselaer Polytechnic Institute, Troy, New York 12180-3590 Received October 26, 2007 ABSTRACT The design of reversible adhesives requires both stickiness and the ability to remain clean from dust and other contaminants. Inspired by gecko feet, we demonstrate the self-cleaning ability of carbon nanotube-based flexible gecko tapes. A gecko has the unique ability to reversibly stick and unstick to a variety of smooth and rough surfaces. The gecko’s wall climbing ability, without the use of vis- coelastic glue, has attracted significant attention.1–11 Although the gecko does not groom its feet, its stickiness remains for months between molts.12 The gecko’s dirty feet can recover its ability to climb vertical walls only after a few steps.12 Our daily experience with sticky tapes has been the opposite. The stickier the adhesive, the more difficult it is to keep it clean from dust and other contaminants. Synthetic self-cleaning adhesives, inspired by the gecko’s feet, could be used for many applications including wall climbing robots and microelectronics. The secret of the gecko’s adhesive properties lies in the Figure 1. Natural and synthetic structures showing self-cleaning 1,13–15 microstructure of gecko feet. Microscopy shows that abilities. (A) SEM image of natural gecko setae. (B) Surface of a gecko feet are covered with millions of small hairs called lotus leaf with hierarchical roughness.16 (C) Hairy structure of lady’s setae, which further divide into hundreds of smaller spatulas mantle leaf.17 (D-E) SEM images of synthetic setae made of (Figure 1A).