CATALOG OF ANTIBODIES FOR MARKERS • Neural • Fibroblast • Organelle • Cancer

For research purposes only. Not for use in humans. Prices subject to change. FAX: 303.730.1966 • WEB: www.novusbio.com 2 Table of Contents Marker Antibodies Stem Cell Markers...... 2-5 Stem Cell Marker Antibodies Hematopoietic Stem Cell ...... 2-5 Mesenchymal Stem Cell ...... 2 Embryonic Stem Cell ...... 2-5 Neuronal Stem Cell ...... 3 Neural Markers ...... 6-12 Keratinocyte Stem Cell ...... 3 Hemangioblast Stem Cell ...... 5

Fibroblast Marker Antibodies ...... 6

Neural Cell Marker Antibodies Musashi 1 Astrocyte/Astroglia Markers ...... 6 Organelle Cell Markers ....12-16 General Glial Cell Markers...... 7 Microglia Markers ...... 7 Neuronal Markers ...... 8-10 Oligodendrocyte Markers ...... 10-11 Schwann Cell Markers...... 11 CancerCMk Markers ...... 17-22 Organelle Cell Marker Antibodies Autophagic Vesicles Markers ...... 12 Centrosome Markers ...... 12 GFAP Endosome Marker...... 13 Endoplasmic Reticulum Markers ...... 13 Application Key Golgi Complex ...... 14 ELISA - Elisa Lysosome Markers ...... 15 FACS - Fluorescent Activated Cell Sorting Mitochondrial Markers ...... 15-16 ICC - Immunocytochemistry Nuclear Markers ...... 16 IF - Immunofluorescence Cancer Marker Antibodies IHC - Immunohistochemistry Breast Cancer ...... 17-19 IHC-Fr - Immunohistochemistry Frozen Colorectal Cancer ...... 19-20 IHC-P - Immunohistochemistry Paraffin ...... 20-21 IP - Immunoprecipitation Prostate Cancer ...... 22 Beta Tubulin 3 RIA - Radioimmunoassay WB - Western Blot

Reactivity Key Am - Amphibian Ha - Hamster Av - Avian Hu - Human Bb - Baboon Ma - Mammal Bv - Bovine Mk - Monkey Ca - Canine Mu - Mouse Ch - Chicken Po - Porcine Dr - Drosophila Rb - Rabbit Eq - Equine Rt - Rat Fe - Feline Ye - Yeast Gp - Guinea Pig Xp - Xenopus

Gt - Goat UCHL1

Daily product updates! 1 TOLL FREE: 888.506.6887 • PHONE: 303.730.1950 www.novusbio.com Stem Cell Markers Functionally, stem cells are able to propagate and the most pluripotent population, having the greatest generate additional stem cells, and can differentiate developmental potential. However, for many into various progenitor cells which further maturate applications adult stem cells may be preferred due along specific lineages. Stem cell markers allow for to ethical issues involved in the derivation of ES cells. the identification and isolation of stem cells in different Stem cell research is poised to allow the development of types of tissues and cell populations. Such markers new therapies through repair, replacement, and allow identification of embryonic, hematopoietic, regeneration of damaged or diseased cells and tissues mesenchymal/stromal, and neural stem cells. making it one of the most exciting frontiers in modern Embryonic stem (ES) cells, derived from the inner cell medicine. mass of preimplantation embryos, are recognized as

CD133 Antibody CD117 Antibody CD34 Antibody Hematopoietic Stem Cell Marker Hematopoietic Stem Cell Marker Hematopoietic Stem Cell Marker NB120-16518 NB600-765 NB600-1071 CD133 is a cell-surface that CD117 is expressed on the surface Staining of murine identifies neural stem cells, which give of hematopoietic stem cells as well as hair follicles using rise to and glial cells. This other cell types. This receptor binds NB600-1071. antibody is expressed on primitive to stem cell factors. hematopoietic stem and progenitor Species: Hu, Mk cells, retinoblastoma, hemangioblasts, Applications: FACS and neural stem cells as well as on Species: Mu developing epithelia. Applications: FACS, IHC, IHC-P, IP, WB Species: Hu, Mu ABCG2 Antibody Applications: ELISA, ICC, IF, IHC, IHC-P, WB Hematopoietic Stem Cell Marker CD34 Antibody NB100-2177 Hematopoietic Stem Cell Marker CD105 Antibody NB100-1934 Mesenchymal Stem Cell Marker ABCG2 (ATP-binding cassette superfamily G member 2) is a NB600-1011 Staining of human hematopoietic stem cell marker that tonsil using This 90 kDa disulfide-linked is found in a wide variety of stem NB100-1934. homodimer is expressed by vascular cells. endothelial cells. It is suggested that CD105 functions in adhesion and embryonic angiogenesis. Species: Hu Applications: ICC, IHC-Fr, IHC-P, WB Species: Hu, Mk Species: Mu Applications: IHC, IP, WB Applications: FACS, IHC-Fr, IP, WB The highly glycosylated 75-120 kD antigen CD34 is possibly an adhesion molecule CRIPTO Antibody CRIPTO Antibody with a putative role in early hematopoiesis Embryonic Stem Cell Marker Embryonic Stem Cell Marker by mediating the attachment of stem cells NB100-1597 NB100-1598 to the bone marrow or Detection of Cripto Detection of Cripto in directly to stromal cells. It could act as a in MDA-MB21 lysate MDA-MB21 lysate scaffold for the attachment of lineage using NB100-1597 using NB100-1598. specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Staining for CD34 has been used to measure angiogenesis, which reportedly predicts Species: Hu Species: Hu tumor recurrence. Applications: WB Applications: WB The cripto is expressed both in embryonic stem cells and during the early phases of embryo development, while, in the adult, it is reactivated in a wide range of epithelial cancers.

Connexin 43 Antibody Connexin 43 Antibody NB100-722 NB300-309 Detection of Detection of Connexin 43 is a negative cell surface Connexin 43 in rat Connexin 43 in rat marker for the stem cell-containing hippocampal lysate cerebellar lysate population of human limbal epithelial (showing using NB300-309. cells. Connexin 43 forms gap-junctional specifity, lane 1) and channels and regulates the permeability lambda-phosphatase of these gap junctions to small organic incubated rat molecules. Gap junctional intercellular Species: Hu, Mu, Mk, Rt Species: Hu, Mu, hippocampal lysate communication is thought to play a key Mk, Rt (negative control, lane Applications: WB role in development and may also be Applications: WB 2) using NB100-722. involved in epilepsy.

For research purposes only. Not for use in humans. Prices subject to change. FAX: 303.730.1966 • WEB: www.novusbio.com 4 Keratin 19 Antibody Musashi-1 Antibody PSCA Antibody Pancreatic Stem Cell Marker Neuronal Stem Cell Marker Prostate Stem Cell Marker NB110-56914 NB100-1759 NB120-15168 Staining of HeLa cells Staining of Staining of human using NB110-56914. neural rosettes breast cancer using using NB100-1759. NB120-15168.

Species: Hu Species: Hu, Mu, Rt Species: Hu Applications: IHC, ICC, FACS, IP, WB Applications: ICC, IHC, IHC-P, WB Applications: IHC-P CK19 is synthesized mainly in embryonic Musashi-1 is important for cell fate and adult simple epithelia, but has also determination, with a role in maintenance been found in stratified epithelia as well. of the stem cell state, differentiation and tumorigenesis.

NANOG Antibodies NB100-58842 NB100-588 Embryonic Stem Cell Markers Staining of mouse Detection of Nanog is a molecular marker that teratoma using Nanog in mouse recognizes the undifferentiated state of NB100-58846. embryonic stem cells stem cells in mouse and human. It is a using NB100-588. divergent homeodomain protein that directs propagation of undifferentiated ES cells. Nanog-deficient embryonic Species: Mu Species: Mu stem cells lose pluripotency and Applications: IHC Applications: IP, WB differentiate into extraembryonic endo- derm lineage.

NB100-59737 NB110-40414 NB100-56450 Detection of Detection of Detection of Nanog Nanog in Nanog in human in (A) HeLa and (B) HeLa nuclear hippocampus tissue NIH/3T3 cells using lysates using lysate using NB100-56450. NB100-59737. NB110-40414.

Species: Hu Species: Hu Species: Hu, Mu, Mk, Gt Applications: ELISA, WB Applications: WB Applications: WB

p63 Antibody Nestin Antibody Nestin Antibody Keratinocyte Stem Cell Marker Neuronal Stem Cell Marker Neuronal Stem Cell Marker NB110-57175 NB300-265 NB100-1604 Detection of nestin in Staining of paraffin- Staining of human fetal temporal embedded human neural stem cells of lobe tissue lysates breast carcinoma the ventricular zone using NB300-265. using NB110-57175. of the CNS using Lane 1: 0.5 ug/ml NB100-1604. Lane 2: 2 ug/ml

Species: Hu, Mu, Rt Species: Hu Species:Speciei s: MuM Applications: FACS, IHC, WB Applications: WB Applications: ICC, IHC Nestin is a Class VI intermediate filament expressed in the developing CNS in early embryonic neuroepithelial stem cells. This protein has been widely used as a predominant p63 Antibody marker for stem/progenitor cells, glioma cells, and tumor endothelial cells. Keratinocyte Stem Cell Marker NB110-57309 Podocalyxin Antibody Podocalyxin Antibody Immunofluorescent Hematopoietic Stem Cell Marker Hematopoietic Stem Cell Marker staining of A431 cells NB110-41503 NB110-41510 using NB110-57309. Detection of Detection of podocalyxin in human podocalyxin in human lung lysate using lung lysate using NB110-41503. NB110-41510. Species: Hu Applications: ICC, IP, WB Species: Hu Species: Hu The p63 gene is highly expressed in the Applications: WB Applications: WB basal or progenitor layers of many epithelial tissues. p63 plays a fundamental Podocalyxin is a CD34 family member expressed by podocytes, vascular endothelia, role associated with development and mesothelia, and a subset of hematopoietic progenitors. Podocalyxin appears to differentiation. complement CD34 as a useful cell surface marker for hemangioblasts, the common precursors of hematopoietic and endothelial cells.

Daily product updates! 5 TOLL FREE: 888.506.6887 • PHONE: 303.730.1950 www.novusbio.com Nucleostemin Antibody Nucleostemin Antibody Nucleostemin Antibody Embryonic Stem Cell Marker Embryonic Stem Cell Marker Embryonic Stem Cell Marker NB100-1569 NB100-2896 NB100-1568 Detection of Staining of human skin Detection of human and mouse basal cells carcinoma human and mouse GNL3 in HeLa, 293T using NB100-2896. GNL3 in HeLa, 293T and 3T3 cells using and 3T3 cells using NB100-1569. NB100-1568.

Species: Hu, Mu Species: Hu, Mu Species: Hu, Mu Applications: IP, WB Applications: IHC Applications: IP, WB Nucleostemin is a protein found in the nucleoli of embryonic stem cells, adult CNS stem cells, primitive cells in the bone marrow, and cancer cells. It is not in the differentiated cells of most adult tissues. It has been suggested to play a role in controlling the cell-cycle progression in stem cells and cancer cells.

The transcription factor OCT4, OCT4 Antibody OCT4 Antibody expressed in ES cells and germ cells, Embryonic Stem Cell Marker Embryonic Stem Cell Marker is strongly implicated in the process of NB100-2379 NB100-41088 maintaining as well as regaining Detection of OCT4 Detection of OCT4 in stem-cell pluripotency and functions as in HeLa whole cell human liver lysate a key regulator of mammalian germline extract using NB using NB100-41088. development. It is expressed in 100-2379. totipotent embryonic stem and germ cells. A critical level of Oct-4 expression is required to sustain stem cell Species: Hu self-renewal and pluripotency. Species: Hu Applications: WB Applications: ELISA, WB

SSEA Antibodies Sca-2 Antibody Sox2 Antibody Embryonic Stem Cell Markers Hematopoietic Stem Cell Marker Embryonic Stem Cell Marker NB100-58797 NB110-37235 SSEA-1 is expressed on the surface Staining of Detection of SOX2 in of preimplantation-stage murine cerebellar Purkinje mouse brain lysate embryos and has been found on neurons using using NB110-37235. the surface of teratocarcinoma stem NB100-58797. cells, but not on their differentiated derivatives. SSEA-3 is synthesized during oogenesis and is present in the membranes of oocytes, zygotes Species: Hu Species: Mu and early cleavage-stage embryos. Applications: IHC-P, IP, WB Applications: IHC, WB Biological roles of these The autosomal dominant cerebellar ataxias The SOX (SRY-box containing gene) carbohydrate-associated molecules (ADCA) are a heterogeneous group of gene family encodes a group of have been suggested in controlling neurodegenerative disorders transcription factors defined by the cell surface interactions during characterized by progressive degeneration conserved high motility group (HMG) development. of the cerebellum, brain stem and spinal DNA-binding domain. They are involved in Undifferentiated primate ES cells, cord. the regulation of embryonic development human EC and ES cells express and in the determination of cell fate. SSEA-3, but not SSEA-1. Undifferentiated mouse ES cells express SSEA-1, but not SSEA-3. Telomerase Antibodies NB100-317 SSEA-1 staining has been seen in the Embryonic Stem Cell Markers Staining of normal pancreas using the oviduct epithelium, endometrium, Telomeres are nucleoprotein structures at NB100-317. epididymis, and in some areas of the ends of eukaryotic . the brain and kidney tubules in adult Telomerase is an enzyme uniquely mice. associated with immortal cell lines and is useful for identifying undifferentiated PSCs. Species: Hu SSEA1 Antibody Applications: FACS, IF, WB NB100-1831 Species: Hu, Mu NB120-32020 NB100-297 Applications: FACS, ICC, IF Staining of paraffin- Detection of hTERT embedded human in MJ90 whole lung adenocarcinoma cell lysate using SSEA3 Antibody using NB120-32020. NB100-297. NB100-1832 Species: Hu Applications: FACS, IF, IHC Species: Hu Species: Hu Applications: FACS, ICC, IHC, WB Applications: IF, WB

For research purposes only. Not for use in humans. Prices subject to change. FAX: 303.730.1966 • WEB: www.novusbio.com 6 Thrombopoietin Antibody TRA 1-60 Antibody TRA 1-81 Antibody Hematopoietic Stem Cell Marker Embryonic Stem Cell Marker Embryonic Stem Cell Marker NB110-68129 NB100-730 NB100-1833 Detection of TPO TRA-1-81 and TRA-1-60 are cell- Immunofluorescence Lane 1: 100ng mouse surface involved in cell staining of TPO (non-reduced) differentiation. Cell surface antigens methanol-fixed Lane 2: 100ng mouse are powerful tools for character- NTERA-2 cl.D1 cells TPO (reduced). izing the function and expression showing membrane of developmentally regulated cells localization using during both embryogenesis and NB100-1833. Species: Mu Species: Hu oncogenesis. Applications: ELISA, WB Applications: FACS, IF, IHC, IP, WB Thrombopoietin (TPO) has been shown to Detection of TRA1-60 in NTERA-2 cell function both as a proliferative and lysate using NB100-730. differentiative factor for megakaryocytes and as a survival and weakly proliferative Species:S Hu factor for hematopoietic stem cells. Applications:A FACS, IF, IHC, IP, WB

VEGFR2 Antibodies Hemangioblast/Stem Cell Markers Receptors for Vascular Endothelial Growth Factor (VEGF), VEGFB and PGF have a tyrosine-protein activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability.

VEGF and its high-affinity binding receptors, the tyrosine FLK1 and FLT1, are thought to be important for the development of embryonic vasculature. It has been shown that an alternately spliced form of FLT1 produces a soluble protein, termed sFLT1, which binds vascular endothelial growth factor with high affinity, playing an inhibitory role in angiogenesis.

NB100-686 NB200-208 NB600-1433 Staining of Staining of Staining of FFPE human myocardium section formalin fixed angiosarcoma using NB200-208. paraffin embedded using The arrowheads human angiosarcoma NB100-686. indicate VEGFR-2 using NB600-1433. positive endothelial cells from myocardial Species: Hu, Mu, Rt Species: Hu, Mu, Rt Species: Hu, Rt capillaries. Applications: IF, IHC-Fr, IHC-P, WB Applications: ELISA, Applications: IHC-P, WB FACS, IHC

NB100-527 NB100-627 NB100-529 Detection of Detection of VEGFR2 Detection of VEGFR-2 VEGFR2 in Chimeric in CSF-1/VEGFR2 in CSF-1 receptor/ CSF-1R/VEGFR2 transfected lysates using VEGFR2 chimera using NB100-527. NB100-627. transfected lysate Lane 1 - 1:2,000 using NB100-529. Lane 2 - 1:10,000

Species: Hu Species: Hu, Mu Species: Hu Applications: WB Applications: IP, WB Applications: WB

NB110-55547 NB100-530 NB110-55548 Detection of VEGFR2 Staining of breast Staining of in VEGFR2 induced carcinoma using breast carcinoma HUVEC lysate using NB110-55548. using NB100-530. NB110-55547.

Species: Hu Species: Hu Species: Hu Applications: IHC Applications: WB Applications: IHC

NB100-2382 NB110-57149 NB110-57644 Detection of Detection of VEGFR2 Detection of VEGFR2 VEGFR2 doublet in ECV304 cell lysate in ECV304 cell lysate in CSF-IR/VEGFR2 using NB110-57149. using NB110-57644. chimera transfected lysate using NB100-2382. Species: Hu Species: Hu Species: Hu Applications: WB Applications: WB Applications: WB

Daily product updates! 7 TOLL FREE: 888.506.6887 • PHONE: 303.730.1950 www.novusbio.com Fibroblast Markers Fibroblasts (Pan Reticular) Antibody Fibroblast (Surface Protein) Antibody Prolyl 4-Hydroxylase Antibody BM4018 SM1214P AF5110 Staining of Staining of KG1 cells Staining of frozen reticular fibroblasts with mouse anti rat skin sections and reticular fibres human fibroblast using AF5110. with BM4018 antibody (SM1214P). antibody.

Species: Hu, Mu Species:Speciei s HuH Species: Rt Applications: IHC-Fr Applications: FACS, IHC, IP Applications: ELISA, IHC, WB

Neural Cell Markers Astrocyte/Astroglia Markers Astrocytes are star-shaped glial cells that perform physical support to neurons, clean up debris within the multiple functions in the CNS. They play a significant brain, provide chemicals to help control fluid role in maintaining normal brain physiology during composition surrounding neurons, and provide development and in adulthood. Astrocytes also provide nutritional support to neurons.

alpha Smooth Muscle Actin Antibody Survivin Antibody ABCA1 Antibody NB120-18460 NB500-201 NB400-105 Staining of human Telophase with Staining of prostate leiomyosarcoma us- accumulation of epithelium using ing NB120-18460. survivin in the mid- NB400-105. bodies of two daughter cells.

Species: Bv, Ch, Hu, Ma, Mu, Rt, Bb Species: Hu, Mu, Ca, Rt, Fe Species:Speciei s Ha,HaH Hu,HuH Mu,Mu Rt Applications: IF, IHC-Fr, IHC-P, WB Applications: IF, WB, IHC-P, IP, ICC. Applications: FACS, ICC, IF, IHC-P, IP, WB Smooth muscle vessels alpha actin has Survivin is also abundantly expressed in In the brain, ABCA1 is expressed in been found in distinct populations of brain tissues (astrocytes and some neurons) neurons, astrocytes, and microglia and astrocytes in the adult mouse brain, in of adult rats following traumatic brain is induced by liver X receptor (LXR) and particular in the corpus callosum and the injury. Survivin has been found retinoid X receptor (RXR) agonists. fornix. However, in the corpus callosum, it co-expressed with NeuN (mature neuronal is seen only in parasagittal planes. Thus, marker) and PCNA (a protein). alpha smooth muscle actin represents a Survivin might affect regulation of neural new marker for subsets of astrocytes. cell proliferative responses after brain injury.

GLAST Antibody GFAP Antibody GFAP Antibody NB100-1869 NB300-141 NB300-142 GLAST expression begins in the Staining of typical Rat cortical newborn and persists throughout astrocytic cells using neurons and in life. This consistency and the fact that NB 300-141 in mixed tissue culture GLAST expression is linked to a func- neurons and glia of stained with Chicken tional role of astrocytes in glutamate rat forebrain. polyclonal to MAP2 - homeostasis makes it a good marker NB300-213 (green) at for astrocyte identification. 1/30000 and Mouse Species: Bv, Hu, Mu, Po, Rt, Fe Species: Hu, Ma Species: Rt monoclonal to GFAP Applications: ICC, IF, IHC, IHC-Fr, Applications: IF, WB Applications: FACS, ICC, IHC, WB - NB300-142 (red) at IHC-P, WB 1/100. Glial fibrillary acidic protein (GFAP) is a member of the class III intermediate filament protein family. It is heavily and specifically expressed in astrocytes and certain other astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in non-myelinating Schwann cells in peripheral nerves. In addition neural stem cells frequently strongly express GFAP. Antibodies to GFAP are therefore very useful as markers of astrocytic cells. In addition many types of brain tumors, presumably derived from astrocytic cells, heavily express GFAP.

For research purposes only. Not for use in humans. Prices subject to change. FAX: 303.730.1966 • WEB: www.novusbio.com 8 General Glial Cell Markers Glial cells are non-neuronal cells that include microglia often referred to as the glue of the CNS, function to and macroglia cells. The latter includes astrocytes, support and protect neurons, maintain homeostasis, oligodendrocytes, ependymal cells, radial glia, form myelin, and partake in signaling in the central Schwann cells and satellite cells. Glial cells, which are nervous system (CNS).

Sox2 Antibody Sox2 Antibody The SOX (SRY-box containing gene) NB110-37235 NB110-37235 gene family encodes a group of Staining of human transcription factors defined by the uterus using Detection of SOX2 in conserved high motility group (HMG) NB110-37235. mouse brain lysate DNA-binding domain. They are using NB110-37235 . involved in the regulation of embryonic development and in the determination of cell fate, and are expressed in the Bergmann glia, a Species: Mu Species: Mu population of radial glia present in Applications: IHC, WB Applications: IHC, WB the Purkinje cell layer.

Vimentin Antibody Vimentin (phospho Ser38) Antibody Vimentin (Phospho Ser72) Antibody NB110-57645 NB110-57646 NB110-57647 Staining of paraffin- Detection of Vimentin Detection of Vimentin embedded human in 1) untreated and in 1) untreated and melanoma using 2) Calyculin A treated 2) Calyculin A treated NB110-57645. HeLa cell lysate using HeLa cell lysate using NB110-57646. NB110-57647.

Species: Hu, Mu, Rt Species: Hu, Mu, Rt Species: Hu, Mu, Rt Applications: IHC, IP, WB Applications: WB Applications: IP, WB

Vimentin (Phospho Ser82) Antibody Vimentin Antibody Vimentin Antibody NB110-57648 NB200-622 NB300-223 Detection of Vimentin Staining of Rat glial cells in mixed in 1) AP treated and formalin-fixed, cerebral cortex cultures 2) untreated HeLa + paraffin-embedded stained with anti- Calyculin A cell lysate human osteosarcoma vimentin (NB 300-223) using NB110-57648. using NB200-622. [green] and counter- stained with anti-GFAP (NB300-142) [red]. Species: Hu, Mu, Rt Species:S i Hu,HM Mu, RtR Species: All Hoechst dye reveals Applications: WB Applications: IHC-P, IP, WB Applications: IF nuclear DNA [blue].

Vimentin is the 10nm or intermediate filament protein subunit found in many kinds of mesenchymal and epithelia cells, in many kinds of cells in tissue culture, and in developing neuronal and astrocytic precursor cells in the central nervous system. Vimentin frequently forms co-polymers with other intermediate filament proteins, such as GFAP (in astrocytes), with desmin (in muscle cells) and proteins (in developing neurons). Antibodies to vimentin are useful in studies of stem cells and are generally used to reveal the filamentous cytoskeleton.

Microglia Markers

Microglia are the smallest glial cells that function CD11 b/c Antibody Ferritin Antibody similarly to macrophages in the blood system. They NB110-40766 NB600-920 Staining of bone are the first immune defense in the CNS that seek and Detection of marrow, Ferritin in destroy damaged neurons, plaques, and infectious myeloid HT1080 agents. When infections cross the blood-brain barrier, precursors using cells using NB110-40766. NB600-920 microglia cells act to increase inflammation in order to using IP.

destroy the infectious agents before they cause damage Species: Hu, Mu Species: Hu to the brain and/or spinal cord. Due to their plasticity, Applications: IHC, IHC-P, WB Applications: ELISA, IHC, IP, WB microglia cells are present in various forms depending on their location in the body, such as ameboid, CD11b is expressed on 8% spleen Ferritin is a a marker for microglia, cells, 44% bone marrow cells and especially for reactive microglia and ramified, phagocytic, juxtavascular, and gitter cells. less than 1% of thymocytes and macrophages. is commonly used as a microglial marker in nervous tissue.

Daily product updates! 9 TOLL FREE: 888.506.6887 • PHONE: 303.730.1950 www.novusbio.com Neuronal Markers Neurons, the functional unit of the nervous system, are tree, and axon, their size, shape, and function varies electrically excitable cells that transmit signals through- greatly. out the body. Generally composed of a soma, dendritic

Acetylcholinesterase Antibody Bag 1 Antibody Beta Tubulin 3 Antibody Early Neuronal Development Neuronal Differentiation Dendrite Marker NB100-1519 NB110-55489 NB100-1612 Detection of ACHE in Staining of paraffin- Dissociated cell culture A431 lysate using embedded colon of a neonatal mouse NB100-1519. carcinoma using brain showing beta NB110-55489. Tubulin 3 (green staining) of neurons.

Species: Hu, Mu Species: Hu, Rt Species: Mu Applications: ELISA, WB Applications: ICC, IHC Applications: ICC, IHC

Acetylcholinesterase, or AChE, Bag1 is a multifunctional protein that Beta III tubulin is abundant in the central hydrolyzes the neurotransmitter, blocks apoptosis and interacts with several and peripheral nervous systems (CNS and acetylcholine at neuromuscular junctions types of proteins, including the Bcl 2 PNS) where it is prominently expressed and brain cholinergic synapses, and thus family proteins. during fetal and postnatal development. terminates signal transmission

c-Fos Antibody Bcl-2 Antibody Bcl-2 Antibody Neuronal Activation Neuronal Apoptosis Inhibitor Neuronal Apoptosis Inhibitor NB600-904 NB200-572 NB100-2087 Staining of rat Staining of Detection of Bcl-2 spinal cord uisng human tonsil using in human lung cell NB600-904. NB200-572. Note extract using absence of staining NB100-2087. of reactive cells in the germinal center. Species: Hu, Mk Species: Hu Species: Hu, Mu, Rt Applications: IHC-P, WB Applications: IHC Applications: IHC-P, IP, WB

c-Fos Antibody Bcl-2 Antibody Bcl-2 Antibody NB120-14285 Neuronal Apoptosis Inhibitor Neuronal Apoptosis Inhibitor Detection of c-Fos in NB300-900 NB110-55551 western blot. Detection of Bcl-2 Staining of paraffin- in human lymph embedded human node lysate using breast carcinoma NB300-900. using NB110-55551.

Species: Bv, Hu, Mu, Rt Applications: WB Species: Hu, Mu, Rt Species: Hu, Mu Applications: ELISA, WB Applications: FACS, ICC, IHC, IP, WB The Fos proteins have been implicated as regulators of cell proliferation, This gene encodes an integral outer mitochondrial membrane protein that blocks the differentiation, and transformation. Fos apoptotic death of some cells. The broad range of protective effects of BCL-2 protein was the first transcription factor identified suggests that BCL-2 may interact with a central step in neural cell death. with a critical function in regulating the development of skeletal cells.

Calretinin Antibody Calretinin Antibody Calretinin Antibody NB110-55651 NB300-707 NB200-618 Staining of paraffin- Detection of Staining of human embedded Human Calretinin rat brain using mesothelioma using homogenates using NB200-618. Note NB110-55651. NB300-707. cytoplasmic and nuclear staining of tumor cells.

Species: Hu, Mu, Rt Species: Hu, Mu, Rt Species: Hu, Mu, Rt, Am Applications: IHC Applications: IP, WB Applications: IHC-P Mesothelial Cell Marker: Calretinin (CAB29, 2) is a calcium binding protein that belongs to calbindin family. It is mainly found in neuronal tissue and is highly expressed in auditory neurons. It has been implicated in a calcium buffer, calcium sensor, and as a regulator of apoptosis. Calretinin is considered a specific marker of mesothelial cells; it is the only marker that has the utility in distinguishing between sarcomatoid and sarcomatoid renal cell carcinomas. It is widely used in the panel of makers for distinguishing mesothlioma from adenocarcinoma.

For research purposes only. Not for use in humans. Prices subject to change. FAX: 303.730.1966 • WEB: www.novusbio.com 10 ChAT Antibody ChAT Antibody Cholinergic Marker Cholinergic Neuron Marker NB100-40794 R-043-100 Detection of ChAT in Staining of rat facial ChAT serves as a specific marker mouse brain lysate nucleus using for cholinergic neurons in both using NB100-40794. Rabbit antibody to ChAT peripheral and central nervous (R-043-100) at 1:2000 systems. It is also present at dilution. parasympathetic postganglionic fibres. Species:S i Rt,RRt MuM Species: Hu, Rt, Rb, Gp Applications: ELISA, WB Applications: ELISA, IHC, WB

ELF Antibody ELF Antibody ELF Antibody Neuronal Precursor Cell Marker Neuronal Precursor Cell Marker Neuronal Precursor Cell Marker NB100-68253 NB100-40828 NB100-55272 Detection of Human Detection of SPTBN1 Staining of human ELF1 in HeLa whole in HeLa and 293T cells prostate cell lysates using using NB100-40828. adenocarcinoma NB100-68253. using NB100-55272.

Species: Hu Species: Hu, Mu Species: Hu Applications: WB Applications: WB, IP Applications: IHC-P Spectrins play a pivotal role in axonal transport, neurite extension, the organization of synaptic vesicles, as well as for protein sorting in the Golgi apparatus and .

HSV-1 Antibody MAP2 Antibody Neuronal Latency Marker Neuronal Dendrite Marker NB110-57251 Following primary NB300-213 10-well HSV-1 infection in humans, Rat neurons stained slides, 10-well HSV-2 herpes simplex virus type with anti-MAP2 slides, anti-Mouse- 1 (HSV-1) establishes (NB300-213) [green] FITC F(ab)2 with latent infections in and anti-GFAP counterstain. sensory neurons. (NB300-142) [red].

Species: All Species: Bv, Hu, Mu, Rt Applications: ELISA, IF, WB Applications: IF, WB

Microtubules are associated with a NQO1 Antibody Nestin Antibody family of proteins called microtubule Neuronal Injury Marker Neuronal Stem Cell Marker associated proteins (MAPs), which NB200-209 NB300-266 includes the protein (tau) and a group Detection of NQO1 Visualization of nestin of proteins referred to as MAP1, MAP2, in A549 lysates using in PC-3 cells using MAP3, MAP4 and MAP5. Antibodies to NB200-209. Lane 1: NB300-266. MAP2 are excellent markers on 0.5 ug/ml. Lane 2: 2 Courtesy of Dolnick neuronal cells, their perikarya and ug/ml. Lab, Roswell Park neuronal dendrites. Cancer Institute. Species: Ca, Hu, Mk, Rt Species: Hu Applications: IF, IHC, IP, WB Applications: ICC, IHC, IF, WB Neuronal damage is associated with an Nestin is a Class VI intermediate filament expressed in the developing central nervous increased activity of NQO1. system (CNS) in early embryonic neuroepithelial stem cells.

Neurofilament Light Antibody Neurofilament Medium Antibody Neurofilament Heavy Antibody NB300-133 NB300-134 NB300-135 Detection of NF-L in Culture of adult Section of rat spinal whole rat cerebellum neural cells. Mature cord stained with homogenate using neurons can be NB300-135 (green) NB300-133. identified by and NB110-58869 morphology and (red). staining.

Species: Bv, Hu, Ma, Mu, Po, Rt, Fe, Av Species: Hu, Ma, Mu, Av Species: Hu, Ma, Mu, Mk Applications: ICC, IF, IHC-Fr, IHC-P, WB Applications: IHC, WB Applications: IHC-Fr, IHC-P, WB

Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. NF-L runs on SDS-PAGE gels at about 68kDa; NF-M at 145-170 kDa; NF-H at 180-220 kDa. Antibodies to the are useful for identifying neuronal cells and their processes in tissue sections, and can also be useful in the diagnostics of neurofilament accumulations seen in many neurological diseases, such as Lou Gehrig’s disease or Alzheimer’s disease.

Daily product updates! 11 TOLL FREE: 888.506.6887 • PHONE: 303.730.1950 www.novusbio.com PGP9.5/UCHL1 Antibodies Peripheral Nerve Fiber Markers PGP9.5 Antibody PGP9.5 Antibody UCLH1 Antibody NB300-675 NB600-1160 NB110-58872 Staining of Staining of rat Shows rat mixed human brain abdominal tissue neuron/glial cultures using NB300-675. using NB600-1160. stained with chicken UCHL1 (green) and rabbit antibody to glial fibrillary acidic protein (GFAP-red), Species: Mu, Hu Species: Hu, Rt Species: Hu, Rt NB300-141. Blue is Applications: IHC, WB Applications: ELISA, IHC-P, WB Applications: IF, WB a DNA stain.

PGP9.5 Antibody NB110-58874 Ubiquitin C-terminal hydrolase 1 (UCHL1) was originally identified as a major ShowsS rat mixed component of the neuronal cytoplasm from 2-dimensional gel analysis of brain tissues, neuron/glialn cultures and was given the name PGP9.5. The protein is extremely abundant representing 1-2% staineds with Rabbit of total brain protein. It was later found that a ubiquitin C-terminal hydrolase enzyme UCHL1U (green). Blue activity was associated with the PGP9.5 protein, resulting in the renaming of PGP9.5 to isi a DNA stain. ubiquitin C-terminal hydrolase 1. Since UCHL1 is heavily expressed in neurons, antibodies to UCHL1 can be used to Species:Speciei s: Hu,HHu Rt identify neurons in histological sections and in tissue culture. The great abundance of Applications: IF, WB this protein in neurons means that it is released from neurons in large amounts following injury or degeneration, so the detection of UCHL1 in CSF and other bodily fluids can be used as a biomarker. UCHL1 was also discovered as a gene mutated in some rare famial forms of Parkinson’s disease. Interestingly, a common allelic variant of UCHL1, the S18Y polymorphism is actually protective against Parkinson’s disease.

Synapsin 1 Antibody Synapsin 1 Antibody NB300-312 NB300-104 Detection of Detection of Synapsin I plays a key role in synaptic plasticity in the synapsin 1 synapsin 1 brain. This effect is due in large part to the ability of in rat in rat the synapsins to regulate the availability of synaptic hippocampal hippocampal vesicles for release. In addition to its role in plasticity, lysate using lysate using the expression of synapsin I is a precise indicator of NB300-312. NB300-104. synapse formation. Thus Synapsin I immunocytochemistry provides a valuable tool for Species: Hu, Mu, Rt Species: Hu, Mu, Rt the study of synaptogenesis. The role of synapsin in Applications: WB Applications: IF, IHC, IP, WB synaptic plasticity and in synaptogensis is regulated by phosphorylation.

Oligodendrocyte Markers

Oligodendrocytes provide support to axons and sheaths are degenerated oligodendrocytes attempt to produce insulating myelin sheaths. The CNS depends replace them, however, in multiple sclerosis patients on this insulation to reduce ion leakage in order to oligodendrocytes themselves are destroyed thus increase overall nerve conduction speed. When myelin compromising their ability to perform repairs.

Amphoterin Antibody CNPase Antibody CNPase Antibody NB100-2322 NB110-79874 NB100-1935 Detection of HMGB1 in Detection of Adult mouse brain whole cell HeLa lysate CNPase in normal showing CNPase using NB 100-2322. brain tissue lysate (brown staining) using NB110-79874. in white matter tracts and the granule cell layer of the Species: Hu, Mu Species:Speciei s: HuH Species: Mu cerebellum. Applications: WB Applications: WB Applications: ICC, IHC

The onset of amphoterin expression, prior 2’,3’-cyclic nucleotide 3’-phosphodiesterase (CNPase) is associated with brain tubulin to the expression of myelin-specific anti- and acts as a microtubule-associated protein in promoting microtubule assembly and gens, makes amphoterin a useful marker distribution. CNPase is used as a marker of cell differentiation in the CNS as it is ex- for studying oligodendrocyte development. pressed primarily in committed oligodendroglial progenitors and terminally-differentiated oligodendrocytes.

For research purposes only. Not for use in humans. Prices subject to change. FAX: 303.730.1966 • WEB: www.novusbio.com 12 MAP-4 Antibody MOG Antibody Olig2 Antibody NB100-74615 NB300-948 NB110-41440 DetectionD of Detection of MOG in Detection of Olig 2 humanh MAP4 in HeLa human brain lysate in Jurkat whole cellc lysate using NB300-948. cell lysates using usingu NB100-74615. NB110-41440.

Species:Speciei s: HuH Species: Hu, Mu, Rt Species: Hu, Mu Applications: IP, WB Applications: ELISA, WB Applications: WB Microtubule-associated protein 4 is a Myelin-Oligodendrocyte Glycoprotein The oligodendroglial lineage marker, major non-neuronal microtubule- (MOG) is a surface marker of Olig2, is expressed in neural progenitors associated protein and is a marker for oligodendrocyte maturation. and oligodendroglia and is essential for astroglia and oligodendroglia cells. oligodendrocyte development.

Nestin Antibody Nestin Antibody Nestin is a marker of oligodendrocyte NB600-876 NB100-1604 lineage cells. Nestin is a Class VI Detection of Nestin A tissue section of intermediate filament expressed in the in MEF whole cell mouse brain showing developing central nervous system lysates using Nestin (green (CNS) in early embryonic NB600-876. staining) in neural neuroepithelial stem cells. This protein stem cells of the has been widely used as a predominant ventricular zone of marker for stem / progenitor cells, the CNS. glioma cells, and tumor endothelial Species: Mu Species: Mu cells. Furthermore, it is a superior Applications: WB Applications: ICC, IHC angiogenic marker to evaluate neovascularity of endothelial cells in tumors.

Schwann Cell Markers

Schwann cells are a type of glial cell that function as peripheral axons in order to increase signal conduction. support cells for the PNS, similar to oligodendrocytes Schwann cells also aid in clearing debris and guide of the CNS. They mainly provide myelin insulation to axon regrowth in the PNS.

Laminin Antibody AN2 Antibody AN2 Antibody NB300-144 NB300-750 NB100-61654 Staining of rat spinal Detection of AN2 in Detection of PAX6 in cord and dorsal mouse eye lysate using rat whole eye extract root tissue using NB NB100-61654. using NB 300-750. 300-144. Pepsin antigen retrieval was performed.

Species: Hu, Mu, Rt Species: Mu, Hu, Ch, Xp, Rt, Sh Species:Speciei s: MuM Applications: IHC-Fr, IHC-P, WB Applications: WB Applications: ELISA, WB AN2 is expressed by immature Schwann cells in vitro and in vivo and downregulated as Laminin Antibody the cells upregulate myelin . NB300-144 Detection of laminin in EHS (1) Ran-1 Antibody SCIP Antibody and heart (2) lysates NB100-1384 NB100-1359 using NB300-144. DetectionD of Ran-1 Detection of SCIP ini 3T3 cell lysate us- in human brain ingi NB100-1384. lysate using NB100-1359. Species: Hu, Mu, Rt Applications: IHC-Fr, IHC-P, WB

Laminin is a marker for human Species:Speciei s: Hu,HHu MuM Species: Hu Schwann cells in vitro. Laminin Applications: ELISA, WB Applications: WB antibodies are widely used to label blood vessels and basement Ran-1 is a marker for normal SCIP, also known as Tst-1 or Oct-6, is membranes. Schwann cells and is associated with expressed in proliferating Schwann adult non-myelin-forming Schwann cells in the PNS and O2A progenitor cells. cells in the developing CNS.

Daily product updates! 13 TOLL FREE: 888.506.6887 • PHONE: 303.730.1950 www.novusbio.com Organelle Markers Autophagic Vesicle Markers Autophagy is an evolutionarily conserved process (autophagosomes) and delivered to lysosomes/vacuoles responsible for the bulk degradation of intracellular for degradation. material. In autophagy, cytoplasmic components are Recent reports indicate that autophagy plays a crucial engulfed by double-membrane-bound structures role in many different pathologies.

APG8a Antibody APG8b Antibody APG8c Antibody R-146-100 R-155-100 R-140-100 Confocal Detection of APG8b Confocal microscopy on in Olfactory cell line microscopy on immunofluorescently (Odora) lysate using immunofluorescently detected MAP1LC3 A R-155-100. detected MAP1LC3 C in cytospin-isolated in cytospin-isolated human white blood human white blood cells. cells. Species: Hu, Rt Species: Hu, Rt Species: Hu Applications: IF, IHC, WB Applications: IF, IHC, WB Applications: IF, IHC, WB

LC3 Antibody LC3 Antibody LC3B Antibody NB100-2220 NB100-2331 NB600-1384 Staining of brain, Staining of brain, Staining of treated cerebral cerebral cortex, cell U373-MG (human cortex, neurons processes in gray glioblastoma) cells using NB100-2220. matter using using NB600-1384. NB100-2331

Species: Hu, Mu, Rt Species: Hu, Mu Species: Hu, Mu Applications: IHC, IHC-P, IP, WB Applications: IHC, IHC-P, IP, WB Applications: ICC, IF, IHC, WB

LC3 is the only known mammalian protein identified that stably associates with the autophagosome membranes. LC3-I is cytosolic and LC3-II is membrane bound and enriched in the autophagic vacuole fraction. The detection of LC3-I to LC3-II conversion is a useful and sensitive marker for distinguishing autophagy in mammalian cells.

Centrosome Markers The centrosome is the main microtubule organizing (PCM). The PCM contains proteins responsible for center (MTOC) of the cell and acts as a regulator of microtubule nucleation and anchoring. Each centriole is cell-cycle progression. Centrosomes are present in composed of nine triplet microtubule blades in a higher eukaryotic cells, but not plant cells. The pinwheel structure. Cancer cells often have an centrosome is composed of two centrioles surrounded abnormal number of centrosomes, which may be of by an amorphous mass of pericentriolar material biological significance. gamma Tubulin Antibody Pericentrin/Kendrin Antibody Pericentrin/Kendrin Antibody NB100-1628 NB100-61071 NB100-61072 Detection of gamma Detection of Detection of Tubulin in chicken Human Pericentrin/ Human Pericentrin/ fibroblasts using Kendrin in HeLa Kendrin in HeLa NB100-1628. cell extracts using cell extracts using NB100-61071. NB100-61072.

Species: Hu Species: Hu Species: Bv, Ca, Ch, Ha, Hu, Mu, Rt, Xp Applications: IP Applications: IP, WB Applications: ELISA, IHC, WB Pericentrin/Kendrin Antibody Gamma tubulin is responsible for Pericentrin binds to and is NB100-68277 binding microtubule minus ends and expressed in the centrosome. It is an integral mediating the link between component of the pericentriolar material Staining of microtubles and the centrosome. (PCM). The protein contains a series of HeLa coiled-coil domains and a highly conserved cells using PCM targeting motif called the PACT domain NB100-68277. near its C-terminus. The protein interacts with gamma-tubulin and is likely important to normal functioning of the centrosomes, Species: Hu cytoskeleton, and cell-cycle progression. Applications: ICC

For research purposes only. Not for use in humans. Prices subject to change. FAX: 303.730.1966 • WEB: www.novusbio.com 14 Endosome Marker EEA1 Antibody NB300-502 Endosomes are membrane-bound vesicles that are Staining of HeLa cells formed by endocytosis. Endocytosis involves using NB300-502. invagination of the plasma membrane to encircle a substance and budding to release the vesicle. Endosomes function to either transport their contents to a lysosome for degradation or to transport substances Species: Ca, Ha, Hu, Mu, Rt, Xp Applications: IF, IP, WB between different portions of the external cell Early endosomal antigen 1 (EEA1) is a 162 membrane, the latter of which is essential for epithelial kDa membrane bound protein component cells whose polarity differs on each side of the specific to the early endosome and is essential for fusion between early endocytic membrane. vesicles.

Endoplasmic Reticulum Markers

The endoplasmic reticulum is an organelle of transport of proteins to the cell membrane, secretion of interconnected tubules, vesicles, and cisternae. Its cellular proteins, sequestration of calcium, and specific functions involve protein translation and folding, production and storage of macromolecules.

WFS1 Antibody PDI Antibody ERp29 Antibody NB100-1918 NB100-1921 NB300-523 Immunoprecipitation Protein disulfide isomerase (PDI) is Staining of of WFS1 using NB an acidic 55 kDa thyroid rat thyrocytes using 100-1918. -binding protein that NB 300-523. Precipitated lysate appears to be identical to the glial- is INS-1. p55 protein. It has been suggested to be involved in disulfide-bond formation and isomerization, as well Species: Bv, Ca, Gp, Ha, Hu, Mu, Mk, Rt Species: Hu, Mu,M Rt as the reduction of disulfide bonds in Applications: IF, IP, WB Applications: IF, IHC-Fr, IP, WB proteins. WFS1 plays an important role in Species: Rt ERp29 resides in the lumen of the maintaining homeostasis of the Applications: ICC, IP, WB ER and is thought to play a role in endoplasmic reticulum (ER) in the pancreas. the processing of secretory proteins within the ER.

ERp57 Antibody Antibody Calreticulin Antibody NB100-1143 NB600-103 NB600-101 Immunofluorescence Detection of ERp57 Detection of staining of in HepG2 lysate using calreticulin in Calreticulin in HCT15 NB100-1143. human kidney lysate colon cancer cells using NB 600-103. using NB 600-101.

Species: Hu Species: Hu Species: Bv, Ha, Hu, Mu, Rt Applications: ELISA, WB Applications: WB Applications: ICC, IF, IHC, IP, WB ERp57 functions together with Calreticulin is a multifunctional, highly conserved Ca2+ -binding protein that is localized to and calreticulin as a the endoplasmic reticulum. molecular of glycoprotein biosynthesis within the ER.

Heme oxygenase-1 Antibody GRP78/BiP Antibody GRP94 Antibody NB110-57028 NB300-520 NB100-41095 Immunofluorescent Detection of GRP78 Detection of GRP94 staining of HeLa in liver, J77, CHQ in 3T3 lysate using cells using and Akt-29 cells NB100-41095. NB110-57028. using NB300-520.

Species: Hu, Mu Species: Ha, Rt, Mu Species:S i MuM Applications: ICC, IHC, IP, WB Applications: IF, IP, WB Applications: ELISA, WB HO-1 catalyzes the NADPH, O2 and Within the ER, misfolded proteins are Glucose-regulated protein 94, also cytochrome P450 reductase dependent detected by Bip(GPR78). known as Grp94 or gp96, is an oxidation of heme to carbon monoxide, abundant resident endoplasmic iron and biliverdin that is immediately reticulum (ER) lumenal stress protein. reduced to bilirubin.

Daily product updates! 15 TOLL FREE: 888.506.6887 • PHONE: 303.730.1950 www.novusbio.com Golgi Complex Markers The Golgi apparatus is a membrane-bound stack of proteins synthesized in the ER and also for cleaving cisternae that processes proteins and lipids synthesized some proteins into smaller fragments. The Golgi in the ER and packages them for transport elsewhere in packages these products in vesicles for transport, either the cell. The Golgi is responsible for glycosylating to destinations inside of the cell or outside of it.

Golgi Marker 58K Antibody GlcNAc transferase Antibody Glucose-6-Phosphate Antibody NB600-412 NB100-57845 NB100-236 Staining of HeLa Detection of GlcNAc Detection of G6PD cells using in rat pancreas lysate in HUVEC cells NB600-412. using NB100-57845. using NB100-236..

Species: Ca, Ha, Hu, Rt Species: Rt, Mu Species: Hu, Mu Applications: ICC, IF, IHC, WB Applications: ELISA, WB Applications: IP, WB

58K protein antibodies are GlcNAc transferase is present as an Glucose-6-Phosphate is an excellent for use as markers for the integral Golgi membrane protein indigenous component of Golgi Golgi complex. and at least the catalytic center of membranes. the transferase is on the lumenal side of the vesicles.

P58 Antibody Syntaxin-6 Antibody TGN38 Antibody NB110-57306 NB100-2920 NB110-40768 Detection of p58 Detection of Immuno- in HeLa cell lysate Syntaxin-6 in human fluorescence using NB110-57306. lymph node lysate staining of TGN38 using NB100-2920. in 3% paraformalde- hyde-fixed Species:S i HuH Species: Hu NRK cells. Species: Mu, Rt Applications: WB Applications: ELISA, WB Applications: IF, WB P58 is a marker of pre-Golgi intermediate Syntaxin-6 is primarily on the trans-Golgi compartment (IC) and a putative marker network (TGN), where it partially for peripheral punctate pre-Golgi interme- colocalizes with the TGN adapter protein TGN38 Antibody diates and the cis-Golgi network. AP-1 on clathrin-coated membranes. NB110-60519 Immuno VPS45 Antibody VPS45 Antibody fluorescence NB100-2431 NB100-41372 staining of TGN38 in 3% Detection of VPS45 in Detection of VPS45 paraformaldehyde- human placenta lysate in human fixed NRK cells. using NB100-2431. peripheral blood mononucleocyte Species: Mu, Rt lysate using Applications: IF, IHC-P, WB NB100-41372. Species: Hu Species: Hu Applications: ELISA, WB Applications: WB TGN38 is a a 38 kDa protein which VPS45 is a member of the sec1 family implicated in Golgi to prevacuolar has been shown to be predominantly compartment trafficking in yeast. Mammalian VPS45 is found in multiple tissues, is localized to the trans Golgi network. partially membrane associated, and is enriched in the Golgi region.

TGN46 Antibody TGN46 Antibody TGN46 Antibody NB110-62093 NB110-40769 NB110-60520 Immunofluorescence Detection of TGN46 Immunofluorescence staining of in HeLa cell lysate staining of human human TGN46 in 3% using NB110-40769. TGN46 in 3% paraformaldehyde- paraformaldehyde- fixed HeLa cells. fixed HeLa cells.

Species: Hu, Mk Species: Hu, Mk Species: Hu, Mk Applications: IF, WB Applications: IF, WB Applications: IF, IHC-P, WB

TGN46 is localized primarily in the Trans-Golgi network. TGN46 has been reported as being the best available marker for human trans-Golgi network.

For research purposes only. Not for use in humans. Prices subject to change. FAX: 303.730.1966 • WEB: www.novusbio.com 16 Lysosome Markers Lysosomes are membrane-bound vacuoles which play acid hydrolases, act as sites for digestion of foreign a critical role in cellular metabolism. These organelles materials and for specialized autolytic cellular participate in endocytosis, the synthesis and assembly of processes.

LAMP1 Antibody LAMP2 Antibody LIMPII/lgp85 Antibody NB120-19294 NB110-11470 NB400-129 Immunofluorescence Staining of mouse Staining of LIMP II in staining of Lamp1 astrocytes rat infarctzone tissue (red) in HeLa cells using NB110-11470. using NB 400-129 using N120-19294. with a DAB detection system.

Species: Hu Species: Ha, Hu, Mu, Mk, Rt, Rb Species: Ca, Hu, Mu, Rt Applications: IF Applications: ICC, IF, IHC, IHC-P, IP, WB Applications: ICC, IHC, IP, WB Lamp1, also known as lysosome Lysosome-associated membrane LIMP II is ubiquitously expressed associated membrane protein 1, is protein 2 (LAMP 2), also known as in most higher organisms and is a a heavily glycosylated membrane lgp2 or lgp110, is a type 1 integral major lysosomal and endosomal protein of the lysosome. membrane protein that is transport- membrane marker. ed from the trans-Golgi network to endosomes and then lysosomes.

Rap1 Antibody Rap1 Antibody Rap1 Antibody NB100-292 NB110-57453 NB110-57454 Localization of RAP1 Staining of paraffin- Staining of paraffin- to Telomeres with embedded human embedded human TRF2 by stomach carcinoma breast cancer tissue Immunofluorescence, using NB110-57453. using NB110-57454. using NB 100-292. Sample: HeLa cells. Species: Hu Species: Hu, Mu, Rt Species: Hu, Mu, Rt Applications: IF, IP, WB Applications: FACS, ICC, IHC, IP, WB Applications: FACS, ICC, IHC, IP, WB Rap1A and Rap1B proteins were localized to late endocytic compartments (late endosomes/lysosomes) in fibroblasts.

Mitochondrial Markers

The mitochondrion is a compartmentalized, dual- their own DNA and ribosomes. The primary function of membraned organelle that is responsible for most mitochondria is to convert energy from glucose into ATP energy production in the cell. Mitochondria contain via oxidative phosphorylation via the Krebs Cycle.

Cytochrome c Antibody Cytochrome c Antibody NB100-56503 NB300-1068 Detection of Staining of heart Cytochrome c is released from Cytochrome C in tissue using mitochondria after tissue injury. It is an HeLa cell lysate using NB300-1068. electron transporting protein that NB100-56503. resides within the intermembrane space of the mitochondria, where it plays a critical role in the process of oxidative phosphorylation and production of cellular Species: Dr, Ha, Eq, Hu, Mu, Rt Species: Hu ATP. Applications: ICC, IF, WB Applications: ELISA, IHC-P, WB

GFP Antibody GFP Antibody GFP Antibody NB600-303 NB600-597 NB100-1770 Recombinant GFP Western blot of GFP GFP recombinant detected using recombinant protein protein detected NB600-303. detected with with NB 100-1770 NB600-597. polyclonal anti-GFP antibody.

Species: All Species: All Species: All Applications: ICC, IHC-P, IP, WB Applications: ELISA, IHC, WB Applications: ELISA, WB

GFP, green fluorescent protein, is a marker for subcellular localization and as a label for plant mitochondria in vivo.

Daily product updates! 17 TOLL FREE: 888.506.6887 • PHONE: 303.730.1950 www.novusbio.com Glutamate dehydrogenase Antibody HSP60 Antibody HSP70 Mitochondrial Antibody NB600-853 NB110-57063 NB300-527 Detection of Staining of paraffin- Staining of Glutamate embedded human human dehydrogenase human breast peripheral blood in bovine liver carcinoma using mononucleocyte preparations using NB110-57063. lysate using NB600-853. NB300-527. Species: Bv Species: Hu, Mu, Rt Species: Hu, Mu Applications: ELISA, WB Applications: IHC, WB Applications: ICC, IP, WB

Glutamate dehydrogenase has long been HSP60 is a transiently expressed HSP70 is known to have been acquired used as a marker for mitochondria in brain mitochondrial protein. from the proto-mitochondrial and other tissues. endosymbiont.

GRK2 Antibody GRK2 Antibody GRK2 is found in many cell types and NB100-2831 NB300-156 may also have a role in the regulation of the microtubular cytoskeleton. The levels Detection of GRK2 in NB300-156 (green) of GRK2 enzymatic activity, protein and Daudi cell lysate versus NF-M (red, NB mRNA are all elevated in a variety of using NB100-2831. 300-134), in rat human heart disease states, and the effect cortex, showing of this may contribute to the reduced mostly large effectiveness of the beta-adrenergic pyramidal neurons. system in these disease states. GRK2 is Species: Hu Species: Hu, Bv, Rt also overexpressed in Alzheimer disease Applications: ELISA, WB Applications: IHC, WB and is an early marker of brain mitochon- drial lesions.

Mitofilin Antibody Mitochondrial Marker Antibody VDAC1 Antibody NB100-1919 NB120-17857 NB100-695 Staining of HeLa cells Staining of human Detection of VDAC1 using NB100-1919. liver using in rat heart lysate . NB120-17857. using NB100-695.

Species: Ca, Hu, Mu, Rt, Fe Species: Hu Species: Hu, Rt Applications: IF, IP, WB Applications: IHC-P Applications: ELISA, WB Analysis of the human heart mitochondrial NB120-17857 recognizes a 60kDa VDAC1 is an outer membrane proteome shows that mitofilin is one of the non-glycosylated protein component of mitochondrial protein. VDACs are highly most abundant mitochondrial proteins. mitochondria found in human cells. It can expressed in heart, liver and skeletal be used to stain the mitochondria in human muscle, where concentrations of samples as a mitochondrial-marker in mitochondria are at their highest. subcellular fractions. Nuclear Markers

The nucleus is the central organelle of the cell, direction of protein synthesis within the cell. The containing a cell’s DNA and coordinating the actions of nucleolous, a membraneless organelle lying within the the cell and the other organelles within the cell. nucleus, manufactures ribosomes for protein synthesis Surrounded by the nuclear envelope, the nucleus is in the cell. responsible for the control of cell division and the

NUP214 Antibody Histone H1 Antibody Fibrillarin Antibody NB110-40634 NB300-373 NB300-269 Staining of Detection of Histone Human SH-SY5Y human ovarian H1 in calf thumus us- cells stained with carcinoma using ing NB300-373. NB300-269, showing NB110-40634. prominent specular nucleolar stainingNB.

Species: Hu Species: Bv, Ch, Hu, Mu, Rb, Rt Species: Hu Applications: ICC, IHC, IHC-P Applications: IHC, WB Applications: WB

Nucleoporin 214 (NUP214) is required for Somatic H1 may act as a marker of nuclear Fibrillarin is an snRNP protein involved in CRM1-mediated nuclear protein export as reprogramming. pre-ribosomal RNA processing. well as cell cycle progression.

For research purposes only. Not for use in humans. Prices subject to change. FAX: 303.730.1966 • WEB: www.novusbio.com 18 Cancer Markers Breast Cancer Breast cancer is the most common cancer in women the United States alone, with an additional 2,000 cases and is second to lung cancer as the most common diagnosed in men. There will be an estimated 40,000 non-skin cancer overall. Approximately 200,000 cases women and 450 men who die in 2008 from breast of breast cancer are diagnosed in women every year in cancer in the United States.

Androgen Receptor Antibody Androgen Receptor Antibody Bcl-2 Antibody NB120-9474 NB300-615 NB200-572 Staining of formalin Staining of Staining of formalin- fixed paraffin embed- primate brain using fixed, paraffin- ded human prostate NB300-615. embedded using NB120-9474. human tonsil using NB200-572.

Species: Hu Species: Hu, Mu, Mk, Rt Species: Hu, Mk Applications: IHC, WB Applications: ICC, IHC, IP, WB Applications: IHC-P, WB

Beta-Catenin Antibody CAIX Antibody CaR Antibody NB110-56924 NB100-417 NB300-601 Immunofluorescent Staining of human Staining of staining of A431 cells RCC tumor Rat-1 using NB110-56924. cryosections using cells using NB100-417. NB300-601.

Species: Hu, Mu Species: Ca, Hu Species: Hu, Rt Applications: ICC, IHC, IP, WB Applications: IF, IHC-P, WB Applications: ICC, IHC, IP, WB

CD24 Antibody Cyclin A Antibody Cyclin A Antibody NB110-500 NB110-56899 NB110-14736 Staining of formalin- Staining of paraffin- Staining of fixed, paraffin- embedded skin formalin fixed embedded human carcinoma using paraffin liver using NB110-56899. embedded NB110-500. human tonsil using NB110-14736.

Species: Hu Species: Hu Species: Hu Applications: IHC Applications: ICC, IHC, IP, WB Applications: IHC, WB

Cyclin A Antibody Cyclin E Antibody Cyclin E Antibody NB110-56898 NB110-56904 NB110-56905 Immunofluorescent Immunofluorescent Staining of paraffin- staining of HeLa cells staining of HeLa cells embedded human using NB110-56898. using NB110-56904. breast carcinoma using NB110-56905.

Species: Hu Species: Hu Species: Hu Applications: ICC, IP, WB Applications: FACS, ICC, IP, WB Applications: ICC, IHC, IP, WB

DAP-kinase Antibody DAP-kinase Antibody ErbB2 Antibody NB110-56925 NB110-56926 NB100-1739 Staining of Immunohistochemical Staining of HeLa cells using staining of paraffin- human breast NB110-56925. embedded human liver adenocarcinoma using carcinoma using NB100-1739. NB110-56926.

Species: Hu Species: Hu, Mu, Rt Species: Hu Applications: ICC, IHC, IP, WB Applications: FACS, IHC, WB Applications: IHC

Daily product updates! 19 TOLL FREE: 888.506.6887 • PHONE: 303.730.1950 www.novusbio.com ErbB-2 Antibody ErbB-2 Antibody ErbB-2 Antibody NB110-57022 NB110-55529 NB110-57021 Immunohistochemical Staining of breast Immunohistochemical analysis of paraffin- carcinoma using staining of paraffin- embedded human NB110-55529. embedded Human breast carcinoma using breast carcinoma NB110-57022. using NB110-57021.

Species: Hu Species: Hu Species: Hu Applications: FACS, IHC, IP, WB Applications: IHC Applications: IHC

ErbB-2 Antibody EZH2 Antibody GATA3 Antibody NB110-57023 NB110-56975 NB600-1184 Immunohistochemical Immunofluorescent IHC staining of staining of paraffin- staining of HeLa cells paraffin embedded embedded human using NB110-56975. human tonsil using breast ductal NB600-1184. carcinoma in situ using NB110-57023. Species: Hu Species: Hu, Mu, Rt Species: Hu Applications: FACS, ICC, IHC, IP Applications: FACS, ICC, IF, IP, WB Applications: IHC, WB

GCDFP-15 Antibody Glut-1 Antibody HIF-1 alpha Antibody NB110-66658 NB120-15310 NB100-479 Staining of human Staining of Immunohistochemical esophagous using placenta, villi using staining of paraffin- NB120-15310. embedded human NB100-479. breast carcinoma using NB110-66658.

Species: Hu Species: Hu, Rt Species: Hu, Mu, Mk, Rt Applications: FACS, ICC, IHC, WB Applications: IHC-P Applications: IHC, WB

HSP70 Antibody Ki67 Antibody KPNA2 Antibody NB110-57064 NB500-170 NB100-1371 Immunohistochemical Staining of FFPE Staining of green staining of paraffin- human tonsil using formaldahyde-fixed embedded human NB500-170. HeLa with prostate carcinoma endogenously using NB110-57064. expressed Histone H2B-GFP fusion as DNA marker. Species: Hu Species: Hu, Mu, Po, Rt Species: Hu Applications: FACS, IHC, IP, WB Applications: ICC, IF, IHC-Fr, IHC-P Applications: ELISA, ICC, IHC, WB

Laminin Antibody Antibody MMP-1 Antibody NB300-144 NB100-62269 NB110-57211 Staining of rat spinal Staining of MDM2- Immunohistochemical cord and dorsal root human breast staining of paraffin- paraformaldehyde/ carcinoma using embedded human paraffin-embedded NB100-62269. cervical carcinoma tissue using using NB100-57211. NB300-144. Species: Hu, Mu, Rt Species: Hu Species: Hu Applications: IHC-Fr, IHC-P, WB Applications: IHC-Fr, IHC-P, IP, RIA, WB Applications: FACS, ICC, IHC, IP, WB

MMP-13 Antibody MMP-2 Antibody Antibody NB110-60992 NB200-193 NB100-1746 Staining of Detection of MMP2 in Staining of human formalin fixed and a paraffin-embedded skin squamous Paraffin embedded human neurofibroma cell carcinoma using human placenta tissue using NB200-193. NB100-1746. using NB110-60992.

Species: Hu Species: Ch, Hu, Mu, Rt Species: Hu Applications: IHC, WB Applications: ELISA, IHC-Fr, IHC-P, WB Applications: IHC

For research purposes only. Not for use in humans. Prices subject to change. FAX: 303.730.1966 • WEB: www.novusbio.com 20 p63 Antibody PKC alpha Antibody PSA Antibody NB100-691 NB110-57353 NB600-835 Staining of formalin Staining of human Staining of fixed paraffin thyroid gland formalin-fixed, embedded human carcinoma using paraffin-embedded skin using NB100-691. NB110-57353. human prostate carcinoma using NB600-835.

Species: Hu, Mu, Rt Species: Hu, Mu, Rt Species:Speciei ss: HuH Applications: IF, IHC-P, IP, WB Applications: FACS, ICC, IHC, IP, WB Applications: IHC-P, WB

SNCG Antibody Survivin Antibody Survivin Antibody NB110-60497 NB500-238 NB500-201 Immunohistochemical Staining of ovary Telophase with staining of carcinoma using accumulation of paraffin-embedded NB500-238. survivin in the mid- human ovary bodies of two carcinoma using daughter cells. NB110-60497. Species: Hu Species: Hu, Mu, Rt Species: Hu, Mu, Ca, Rt, Fe Applications: ELISA, IHC-Fr, IHC-P, WB Applications: ICC, IF, IHC, IHC-P, WB Applications: IF, WB, IHC-P, IP, ICC.

Colorectal Cancer Although only a quarter of diagnosed colorectal tumors malignant colorectal tumors are adenocarcinomas, are malignant, this portion still accounts for 150,000 although lymphomas, leiomyosarcomas, and carcinoids cases of colorectal cancer in the United states each can also occur in the colorectal region. year, resulting in nearly 50,000 deaths. Nearly all

Bcl-2 Antibody Caspase 7 Antibody CDX-2 Antibody NB200-572 NB110-55664 NB110-40734 Staining of FFPE Formalin-fixed, Immunofluorescent human ovarian paraffin-embedded staining of HeLa cells carcinoma human tonsil stained using NB110-55664. using NB110-40734. using NB 200-572.

Species: Hu, Mk Species: Hu Species: Hu Applications: IHC-P, WB Applications: ICC, IHC, IP, WB Applications: IHC

CDX-2 Antibody Cyclooxygenase-2 Antibody Galectin-3 Antibody NB100-699 NB100-689 NB300-538 Immunohistochemical Staining of formalin Staining of rat staining using fixed paraffin olfactory bulb using NB100-699. embedded human NB300-538. colon carcinoma using NB100-689.

Species: Hu Species: Hu, Mu, Rt Species:S i Hu,H Mu,M RtRt Applications: IHC Applications: IHC-Fr, IHC-P, IP, WB Applications: ELISA, FACS, IF, IHC, IP, WB

Ki67 Antibody Ki67 Antibody MMP-9 Antibody NB500-170 NB600-1209 NB110-57222 Staining of FFPE Staining of human Immunohistochemical human tonsil lymph node using staining of paraffin- using NB500-170. NB600-1209. embedded human lymphoma using NB110-57222.

Species: Hu, Mu, Po, Rt Species: Hu Species: Hu Applications: ICC, IF, IHC-Fr, IHC-P Applications: IHC, IHC-Fr, WB Applications: FACS, ICC, IHC, WB

Daily product updates! 21 TOLL FREE: 888.506.6887 • PHONE: 303.730.1950 www.novusbio.com MMP-9 Antibody MMP-9 Antibody MUC1 Antibody NB110-57223 NB100-59029 NB120-15481 Immunohistochemical Staining of skin Staining of staining of paraffin- granulation breast carcinoma embedded human tissue using using breast carcinoma using NB100-59029. NB120-15481. NB110-57223.

Species: Hu Species: Hu Species: Hu, Mu Applications: FACS, IHC, WB Applications: IHC-P Applications: IHC-P, WB

Osteopontin Antibody p63 Antibody PGP9.5 Antibody NB600-1043 NB110-57309 NB600-1160 Staining of human Immunofluorescent Staining of rat breast tumor cells staining of A431 cells abdominal tissue using NB600-1043. using NB110-57309. using NB600-1160.

Species: Ca, Hu, Po Species: Hu Species: Hu, Rt Applications: IHC, WB Applications: ICC, IP, WB Applications: ELISA, IHC-P, WB

SMAD4 Antibody STAT3 Antibody Telomerase Antibody NB110-57582 NB110-57596 NB600-476 Immunohistochemical Immunofluorescence Immunohistochemical staining of paraffin- microscopy of Saos-2 staining of paraffin- embedded lung cells transduced with embedded human squamous carcinoma a retroviral vector lung carcinoma using using NB110-57596. NB110-57582. expressing hTERT and GFP rom an internal ribosomal entry site. Species: Hu, Mu, Rt Species:S i HuH Species: Hu Applications: FACS, ICC, IHC, IP, WB Applications: ICC, IHC, IP, WB Applications: IF, IHC, IP, WB

Telomerase Antibody TEM-8 Antibody VEGF-D Antibody NB100-317 NB110-17405 NB110-60973 Staining of normal Immunohistochemi- Formalin fixed and pancreas using cal staining of human Paraffin embedded NB100-317. brain tissue using human placenta tissue NB110-17405. using NB110-60973.

Species: Hu Species: Hu, Mu, Rt Species: Hu Applications: FACS, IF, WB Applications: IHC, WB Applications: IHC, WB

Lung Cancer Lung cancer is the most common non-skin cancer, with deaths. While most cases of lung cancer are related to an estimated 215,000 new cases diagnosed in 2008 smoking, there are other risk factors including genetics, in the United States. Additionally, more than 160,000 family history of lung cancer and exposure to chemi- people will die in the United States from lung cancer in cals and pollution. 2008, making lung cancer the leading cause of cancer

MUC16 Antibody Antibody CEA Antibody NB200-562 NB110-55646 NB120-15987 Staining of Immunohistochemical Staining of formalin human lung tissue staining of paraffin- fixed paraffin (alveolocytes embedded human embedded type II) using thyroid using human colon NB200-562. NB110-55646. carcinoma using NB120-15987.

Species: Hu Species: Hu, Mu, Rt Species: Hu Applications: ELISA, IHC-P, WB Applications: IHC Applications: ELISA, IHC-P

For research purposes only. Not for use in humans. Prices subject to change. FAX: 303.730.1966 • WEB: www.novusbio.com COX-2 Antibody CEA Antibody hTERT Antibody NB100-689 NB120-15287 NB100-317 Staining of formalin Staining of Staining of pancreatic fixed paraffin embed- formalin fixed carcinoma using ded human paraffin embedded NB100-317. colon carcinoma using human breast using NB100-689. NB120-15287.

Species: Hu, Mu, Rt Species:S i HuH Species: Hu Applications: IHC-Fr, IHC-P, IP, WB Applications: IHC Applications: FACS, IHC-P, IF, WB

Ki67 Antibody Ki67 Antibody MAP-2 Antibody NB110-57147 NB600-1252 NB110-58369 Immunohistochemical Staining of formalin- MAP-2-positive staining of paraffin- fixed, paraffin- cultured neurons embedded Human embedded human (green) from an e13.5 tonsil using tonsil using mouse brain. Nuclei NB110-57147. NB600-1252. are blue.

Species: Hu, Mu, Rt Species: Hu, Rt Species: Mu Applications: IHC Applications:IHC-Fr, IHC-P Applications: ICC, IHC, IHC-P, WB

MAP-2 Antibody NSE Antibody NSE Antibody NB300-213 NB110-58870 NB100-1606 Rat neurons stained Staining of Dissociated cell with anti-MAP2 (NB HEL293 cells using cultures of neonatal 300-213) [green] NB110-58870. mouse brains, showing and anti-GFAP (NB NSE-2 (green staining) 300-142) [red]. in neurons.

Species: Bv, Hu, Mu, Rt Species: Hu, Rt Species: Mu Applications: IF, WB Applications: IF, WB Applications: ICC, IHC

Osteopontin Antibody Osteopontin Antibody p63 Antibody NB600-1043 NB100-1883 NB100-691 Staining of human Staining of Staining of formalin breast tumor paraffin embedded fixed paraffin using NB600-1043. human tonsil using embedded NB100-1883. human skin using NB100-691.

Species: Ca, Hu, Po Species: Hu Species: Hu, Mu, Rt Applications: IHC, WB Applications: ELISA, IHC, IHC-P, WB Applications: IF, IHC-P, IP, WB p63 Antibody PGP9.5 Antibody Smac Antibody NB110-57309 NB300-675 NB110-56936 Staining of A431 cells Staining of Immunohistochemical using NB110-57309. human staining of paraffin- brain using embedded human NB300-675. skin cancer tissue using NB110-56936.

Species: Hu Species: Mu Species: Hu, Rt Applications: ICC, IP, WB Applications: IHC, WB Applications: FACS, ICC, IHC, IP, WB

Survivin Antibody Telomerase Antibody UCHL1 Antibody NB500-237 NB600-476 NB300-676 Staining of lung Immunofluorescence Staining of carcinoma using staining of Saos-2 human NB500-237. cells transduced with brain using a retroviral vector NB300-676. expressing hTERT using NB600-476.

Species: Hu Species:S i HuH Species: Mu Applications: IF, IHC, WB Applications: IF, IHC, IP, WB Applications: IHC, WB

Daily product updates! TOLL FREE: 888.506.6887 • PHONE: 303.730.1950 www.novusbio.com Prostate Cancer For men in the United States, prostate cancer is the cancer diagnoses and deaths have declined in recent most common non-skin cancer and is the second most years after rising in the 1980s because of new detection deadly cancer. With over $8 billion spent annually in techniques. Nearly 1 in 6 men will be diagnosed with the United States on prostate cancer research, prostate prostate cancer at some point in their lives.

Bcl-2 Antibody Caveolin-1 Antibody Caveolin-1 Antibody NB110-55551 NB100-615 NB110-39015 Immunohistochemical Staining of EaHy926 Staining of staining of paraffin- endothelial cell line respiratory epithelium embedded human using NB100-615. and alveole using breast carcinoma using NB110-39015. NB110-55551.

Species: Hu, Mu Species: Hu, Mu, Rt Species: Hu Applications: FACS, ICC, IHC, IP, WB Applications: IF, IP, WB Applications: IHC

Caveolin-1 Antibody DPP4 Antibody DPP4 Antibody NB110-39016 NB100-58756 NB100-59021 Staining of respiratory Staining of placenta Staining of placenta epithelium, bronchial using NB100-58756. using NB100-59021. smooth muscle, and alveoli using NB110- 39016.

Species: Hu Species: Hu Species: Hu Applications: IHC Applications: IHC-P Applications: IHC-P

E- Antibody HGF Antibody Ki67 Antibody NB110-56937 NB110-57200 NB600-1209 Immunohistochemical Immunohistochemical Staining of human staining of paraffin- staining of paraffin- lymph node using embedded human embedded human NB600-1209. hepatocellular carci- breast carcinoma noma using NB110- using NB110-57200. 56937.

Species: Hu, Mu Species: Hu Species: Hu Applications: ICC, IHC, IP, WB Applications: ICC, IHC, WB Applications: IHC, IHC-Fr, WB

LDH Antibody MCM7 Antibody PCNA Antibody NB110-57161 NB110-57188 NB500-106 Immunohistochemical Immunohistochemical Immunohistochemical staining of paraffin- staining of paraffin- staining of paraffin- embedded human embedded human embedded human testis carcinoma using lung tissue using colon carcinoma, NB110-57161. NB110-57188. using NB500-106.

Species: Hu Species: Hu, Mu, Rt Species: Ch, Dr, Hu, Mu, Rt, Ye Applications: FACS, IHC, WB Applications: FACS, ICC, IHC, IP, WB Applications: IHC, IP, WB

PSA Antibody PSA Antibody S100A6 Antibody NB110-59960 NB600-835 NB100-1765 Immmunohistochemical Staining of formalin- Immunohistochemical staining of paraffin- fixed, paraffin- staining of paraffin-em- embedded human embedded human bedded brain glioma prostate carcinoma prostate carcinoma tissue using NB100- using NB110-59960. using NB600-835. 1765.

Species: Hu Species: Hu Species: Hu Applications: IHC-P, WB Applications: IHC-P, WB Applications: ELISA, IHC, WB

For research purposes only. Not for use in humans. Prices subject to change. FAX: 303.730.1966 • WEB: www.novusbio.com 22 U.S. ORDERING Phone: 303.730.1950 888.506.6887 Fax: 303.730.1966 Email: [email protected] Internet: www.novusbio.com

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